Implementation Science to Achieve Equity in Heart Failure Care: A Scientific Statement From the American Heart Association
Circulation. 2024 Apr 3. doi: 10.1161/CIR.0000000000001231. Online ahead of print.ABSTRACTGuideline-directed medical therapies and guideline-directed nonpharmacological therapies improve quality of life and survival in patients with heart failure (HF), but eligible patients, particularly women and individuals from underrepresented racial and ethnic groups, are often not treated with these therapies. Implementation science uses evidence-based theories and frameworks to identify strategies that facilitate uptake of evidence to improve health. In this scientific statement, we provide an overview of implementation trials in HF...
Source: Circulation - April 3, 2024 Category: Cardiology Authors: Khadijah Breathett Sabra Lewsey Nicholas K Brownell Kendra Enright Lorraine S Evangelista Nasrien E Ibrahim Jose Iturrizaga Daniel D Matlock Modele O Ogunniyi Madeline R Sterling Harriette G C Van Spall American Heart Association Heart Failure and Transpl Source Type: research

Implementation Science to Achieve Equity in Heart Failure Care: A Scientific Statement From the American Heart Association
Circulation. 2024 Apr 3. doi: 10.1161/CIR.0000000000001231. Online ahead of print.ABSTRACTGuideline-directed medical therapies and guideline-directed nonpharmacological therapies improve quality of life and survival in patients with heart failure (HF), but eligible patients, particularly women and individuals from underrepresented racial and ethnic groups, are often not treated with these therapies. Implementation science uses evidence-based theories and frameworks to identify strategies that facilitate uptake of evidence to improve health. In this scientific statement, we provide an overview of implementation trials in HF...
Source: Circulation - April 3, 2024 Category: Cardiology Authors: Khadijah Breathett Sabra Lewsey Nicholas K Brownell Kendra Enright Lorraine S Evangelista Nasrien E Ibrahim Jose Iturrizaga Daniel D Matlock Modele O Ogunniyi Madeline R Sterling Harriette G C Van Spall American Heart Association Heart Failure and Transpl Source Type: research

Implementation Science to Achieve Equity in Heart Failure Care: A Scientific Statement From the American Heart Association
Circulation. 2024 Apr 3. doi: 10.1161/CIR.0000000000001231. Online ahead of print.ABSTRACTGuideline-directed medical therapies and guideline-directed nonpharmacological therapies improve quality of life and survival in patients with heart failure (HF), but eligible patients, particularly women and individuals from underrepresented racial and ethnic groups, are often not treated with these therapies. Implementation science uses evidence-based theories and frameworks to identify strategies that facilitate uptake of evidence to improve health. In this scientific statement, we provide an overview of implementation trials in HF...
Source: Circulation - April 3, 2024 Category: Cardiology Authors: Khadijah Breathett Sabra Lewsey Nicholas K Brownell Kendra Enright Lorraine S Evangelista Nasrien E Ibrahim Jose Iturrizaga Daniel D Matlock Modele O Ogunniyi Madeline R Sterling Harriette G C Van Spall American Heart Association Heart Failure and Transpl Source Type: research

Association Between Chest Compression Pause Duration and Survival After Pediatric In-Hospital Cardiac Arrest
CONCLUSIONS: Each 5-second increment in longest CC pause duration during pediatric in-hospital cardiac arrest was associated with lower chance of survival with favorable neurological outcome, survival to hospital discharge, and return of spontaneous circulation. Any CC pause >10 seconds or >20 seconds and number of pauses >10 seconds and >20 seconds were significantly associated with lower adjusted probability of return of spontaneous circulation, but not survival or neurological outcomes.PMID:38563137 | DOI:10.1161/CIRCULATIONAHA.123.066882 (Source: Circulation)
Source: Circulation - April 2, 2024 Category: Cardiology Authors: Kasper G Lauridsen Ryan W Morgan Robert A Berg Dana E Niles Monica E Kleinman Xuemei Zhang Heather Griffis Jimena Del Castillo Sophie Skellett Javier J Lasa Tia T Raymond Robert M Sutton Vinay M Nadkarni pediRES-Q Investigators Source Type: research

Association Between Chest Compression Pause Duration and Survival After Pediatric In-Hospital Cardiac Arrest
CONCLUSIONS: Each 5-second increment in longest CC pause duration during pediatric in-hospital cardiac arrest was associated with lower chance of survival with favorable neurological outcome, survival to hospital discharge, and return of spontaneous circulation. Any CC pause >10 seconds or >20 seconds and number of pauses >10 seconds and >20 seconds were significantly associated with lower adjusted probability of return of spontaneous circulation, but not survival or neurological outcomes.PMID:38563137 | DOI:10.1161/CIRCULATIONAHA.123.066882 (Source: Circulation)
Source: Circulation - April 2, 2024 Category: Cardiology Authors: Kasper G Lauridsen Ryan W Morgan Robert A Berg Dana E Niles Monica E Kleinman Xuemei Zhang Heather Griffis Jimena Del Castillo Sophie Skellett Javier J Lasa Tia T Raymond Robert M Sutton Vinay M Nadkarni pediRES-Q Investigators Source Type: research

BRCC3 Regulation of ALK2 in Vascular Smooth Muscle Cells: Implication in Pulmonary Hypertension
CONCLUSIONS: These results suggest a pivotal role of BRCC3 in sustaining pulmonary vascular homeostasis by maintaining the integrity of the BMP signaling (ie, the ALK2-Smad1/5-PPARγ axis) while suppressing TGF-β signaling in PASMCs. Such rebalance of BMP/TGF-β pathways is translationally important for PAH alleviation.PMID:38557054 | DOI:10.1161/CIRCULATIONAHA.123.066430 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Hui Shen Ya Gao Dedong Ge Meng Tan Qing Yin Tong-You Wade Wei Fangzhou He Tzong-Yi Lee Zhongyan Li Yuqin Chen Qifeng Yang Zhangyu Liu Xinxin Li Zixuan Chen Yi Yang Zhengang Zhang Patricia A Thistlethwaite Jian Wang Atul Malhotra Jason X-J Yuan John Y-J Sh Source Type: research

LXR α Promotes Abdominal Aortic Aneurysm Formation Through UHRF1 Epigenetic Modification of miR-26b-3p
CONCLUSIONS: Our study reveals a pivotal role of the LXRα/UHRF1/miR-26b-3p axis in AAA and provides potential biomarkers and therapeutic targets for AAA.PMID:38557060 | DOI:10.1161/CIRCULATIONAHA.123.065202 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Xiao Guo Jianmei Zhong Yichao Zhao Yanan Fu Ling-Yue Sun Ancai Yuan Junling Liu Alex F Chen Jun Pu Source Type: research

Modernizing Cardiovascular Medicine Board Certification: Leveraging Innovation and Strengthening Continuous Competency and Professional Growth
Circulation. 2024 Apr 1. doi: 10.1161/CIRCULATIONAHA.124.069553. Online ahead of print.NO ABSTRACTPMID:38557064 | DOI:10.1161/CIRCULATIONAHA.124.069553 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Joseph C Wu B Hadley Wilson James C Fang Jodie L Hurwitz George D Dangas Source Type: research

Highlights From the < em > Circulation < /em > Family of Journals
Circulation. 2024 Apr 2;149(14):1139-1144. doi: 10.1161/CIRCULATIONAHA.124.069400. Epub 2024 Apr 1.NO ABSTRACTPMID:38557122 | DOI:10.1161/CIRCULATIONAHA.124.069400 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Source Type: research

Preemptive Versus Urgent Heart Failure Hospitalization as a Surrogate for Mortality Risk in Heart Failure
Circulation. 2024 Apr 2;149(14):1062-1064. doi: 10.1161/CIRCULATIONAHA.123.068066. Epub 2024 Apr 1.NO ABSTRACTPMID:38557123 | DOI:10.1161/CIRCULATIONAHA.123.068066 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Chris J Kapelios Lars H Lund Source Type: research

Prevention of Sudden Cardiac Death: Beyond Automated External Defibrillators and Implantable Cardioverter Defibrillators
Circulation. 2024 Apr 2;149(14):1059-1061. doi: 10.1161/CIRCULATIONAHA.123.066984. Epub 2024 Apr 1.NO ABSTRACTPMID:38557124 | DOI:10.1161/CIRCULATIONAHA.123.066984 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Sumeet S Chugh Source Type: research

Distinct Plasma Extracellular Vesicle Transcriptomes in Acute Decompensated Heart Failure Subtypes: A Liquid Biopsy Approach
Circulation. 2024 Apr 2;149(14):1147-1149. doi: 10.1161/CIRCULATIONAHA.123.065513. Epub 2024 Apr 1.NO ABSTRACTPMID:38557125 | DOI:10.1161/CIRCULATIONAHA.123.065513 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Priyanka Gokulnath Michail Spanos H Immo Lehmann Quanhu Sheng Rodosthenis Rodosthenous Mark Chaffin Dimitrios Varrias Emeli Chatterjee Elizabeth Hutchins Guoping Li George Daaboul Farhan Rana Ashley Mingyi Wang Kendall Van Keuren-Jensen Patrick T Ellinor Source Type: research

Correction to: INO80-Dependent Remodeling of Transcriptional Regulatory Network Underlies the Progression of Heart Failure
Circulation. 2024 Apr 2;149(14):e1066. doi: 10.1161/CIR.0000000000001235. Epub 2024 Apr 1.NO ABSTRACTPMID:38557126 | DOI:10.1161/CIR.0000000000001235 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Source Type: research

Intravascular Imaging for Guiding Percutaneous Coronary Intervention: What Does the Totality of Data Suggest, and Where Should We Go?
Circulation. 2024 Apr 2;149(14):1087-1089. doi: 10.1161/CIRCULATIONAHA.123.067916. Epub 2024 Apr 1.NO ABSTRACTPMID:38557127 | DOI:10.1161/CIRCULATIONAHA.123.067916 (Source: Circulation)
Source: Circulation - April 1, 2024 Category: Cardiology Authors: Akiko Maehara Yoichiro Sugizaki Source Type: research

Advancing Wearable Biosensors for Congenital Heart Disease: Patient and Clinician Perspectives: A Science Advisory From the American Heart Association
Circulation. 2024 Mar 28. doi: 10.1161/CIR.0000000000001225. Online ahead of print.ABSTRACTWearable biosensors (wearables) enable continual, noninvasive physiologic and behavioral monitoring at home for those with pediatric or congenital heart disease. Wearables allow patients to access their personal data and monitor their health. Despite substantial technologic advances in recent years, issues with hardware design, data analysis, and integration into the clinical workflow prevent wearables from reaching their potential in high-risk congenital heart disease populations. This science advisory reviews the use of wearables i...
Source: Circulation - March 28, 2024 Category: Cardiology Authors: Animesh Tandon Jennifer N Avari Silva Ami B Bhatt Colin K Drummond Allison C Hill Amanda E Paluch Sheradon Waits Jenny E Zablah Kevin C Harris Council on Lifelong Congenital Heart Disease and Heart Health in the Young (Young Hearts); Council on Lifestyle Source Type: research