Transcutaneous electrical nerve stimulation, acupuncture, and spinal cord stimulation on neuropathic, inflammatory and, non-inflammatory pain in rat models.
Authors: Sato KL, Sanada LS, Silva MDD, Okubo R, Sluka KA Abstract Background: Transcutaneous electrical nerve stimulation (TENS), manual acupuncture (MA), and spinal cord stimulation (SCS) are used to treat a variety of pain conditions. These non-pharmacological treatments are often thought to work through similar mechanisms, and thus should have similar effects for different types of pain. However, it is unclear if each of these treatments work equally well on each type of pain condition. The purpose of this study was to compared the effects of TENS, MA, and SCS on neuropathic, inflammatory, and non-inflammatory ...
Source: Korean Journal of Pain - April 4, 2020 Category: Anesthesiology Tags: Korean J Pain Source Type: research

Spinal cord stimulation in chronic pain: technical advances.
Authors: Isagulyan E, Slavin K, Konovalov N, Dorochov E, Tomsky A, Dekopov A, Makashova E, Isagulyan D, Genov P Abstract Chronic severe pain results in a detrimental effect on the patient's quality of life. Such patients have to take a large number of medications, including opioids, often without satisfactory effect, sometimes leading to medication abuse and the pain worsening. Spinal cord stimulation (SCS) is one of the most effective technologies that, unlike other interventional pain treatment methods, achieves long-term results in patients suffering from chronic neuropathic pain. The first described mode of SCS...
Source: Korean Journal of Pain - April 4, 2020 Category: Anesthesiology Tags: Korean J Pain Source Type: research

Comparative efficacy of medical treatment versus surgical sphincterotomy in the treatment of chronic anal fissure
Conclusion: LIS is still the gold standard for the treatment of chronic anal fissure when the physicians would like to avoid recurrence and obtain the best pain relief. (Source: Nigerian Journal of Clinical Practice)
Source: Nigerian Journal of Clinical Practice - April 4, 2020 Category: Rural Health Authors: T Acar N Acar F G & #252;ng & #246;r E Kamer H Gen & #231; K Atahan ON Dilek M Hac & #305;yanl & #305; Source Type: research

Bilateral calcaneal insufficiency fractures due to chronic carbamazepine use for trigeminal neuralgia: A case report
We report here a 41-year-old lady suffering from bilateral heel pain without trauma history. Her complaining did not respond to analgesics and stretching exercises of plantar fascia. In her past medical history she reported ongoing carbamazepine (CBZ) use over 8 years for trigeminal neuralgia. She had had low bone mineral density; defined as osteopenia. Both calcaneus MRI revealed bilateral stress fractures of calcaneum. She had been advised immobilization for 6 weeks, vitamin D and calcium supplements. CBZ has been stopped by neurology specialist and she had undergone microvascular decompression surgery for intractable pa...
Source: Nigerian Journal of Clinical Practice - April 4, 2020 Category: Rural Health Authors: O Kaya C Hurel G Gumussuyu O Kose Source Type: research

Lack of Data-driven Treatment Guidelines and Wide Variation in Management of Chronic Pelvic Pain in Adolescents and Young Adults
Current literature lacks data-driven guidelines for surgical treatments of adolescents and young adults (AYAs) with chronic pelvic pain. We hypothesized that there is a significant variation in treatment of these patients, which may be an indicator of over or under treatment by some providers. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 4, 2020 Category: OBGYN Authors: Ya-Ching Hung, Maggie L. Westfal, David C. Chang, Cassandra M. Kelleher Source Type: research

A review of discogenic pain management by interventional techniques
Reddy RavikanthJournal of Craniovertebral Junction and Spine 2020 11(1):4-8 This review article describes the various image guided interventional techniques used for treating chronic backache attributed to disc related pathologies. With the aim of minimum invasion and maximum relief, these procedures comprise predominantly of annuloplasty and disc decompression via different mechanisms. Newer therapies are discussed in this review article with the objective of restoring disc height and its biomechanical function by substitution of biochemical constituents, regeneration of cartilaginous end plate and finally artificial dis...
Source: Journal of Craniovertebral Junction and Spine - April 4, 2020 Category: Orthopaedics Authors: Reddy Ravikanth Source Type: research

High ankle sprain: sonographic demonstration of a posterior inferior tibiofibular ligament avulsion
AbstractSyndesmotic injuries, also referred as high ankle sprains, may cause significant ankle instability and chronic pain. Ultrasound (US) is a well-proven imaging modality to evaluate the ligaments of the ankle, due to its high spatial resolution and the possibility to perform dynamic examinations. However, considering the syndesmosis complex, the sonographic appearance of the posterior inferior tibiofibular ligament (PITFL) is not well described in the pertinent literature and, to the best of our knowledge, we found no report of PITFL avulsion demonstrated at US, as in the case presented. (Source: Journal of Ultrasound)
Source: Journal of Ultrasound - April 4, 2020 Category: Radiology Source Type: research

[Giant left ventricular false aneurysme revealing a silent myocardial infarction].
We report a case of a 56-year-old man with a medical history of chronic cigarette smoking, dyslipidemia, and obesity. The patient had no myocardial infarction before. He was admitted for evaluation of important shortness of breath at effort without chest pain for 5 months. Physical exam find an enlarged left ventricular. The electrocardiogram revealed Q waves and ST segment elevation in leads V1 to V6. Transthoracic echocardiogram showed a large thrombosed apical left ventricular false aneurysm, severe left ventricular dysfunction, which were confirmed by cardiac magnetic resonance imaging, this exam also showed no viabili...
Source: Annales de Cardiologie et d'Angeiologie - April 4, 2020 Category: Cardiology Authors: Kadiri R, Fellat N, Doghmi N, Fellat R Tags: Ann Cardiol Angeiol (Paris) Source Type: research

Primary Renal Carcinoid Tumor: Report of Two Cases.
This report describes 2 cases of primary renal carcinoid tumor with unique presentations and management in our regional health care system. Because primary renal carcinoid tumors are quite uncommon, there are no clear established guidelines on preoperative imaging or posttreatment surveillance in patients with these tumors. There remains a large amount of variability in the diagnosis, workup, immunohistochemical analysis, treatment, and surveillance of patients with primary renal carcinoid tumors. As we learn more about this disease, we hope to optimize patient outcomes and standardize pretreatment workup and posttreatment...
Source: The Permanente journal - April 3, 2020 Category: General Medicine Tags: Perm J Source Type: research

Impact of antihypertensive treatment on resiliency to clinical pain
Conclusion: Uncontrollable reduction of high BP in some patients with hypertension could increase the risk for chronic pain incidence and its severity. Practical recommendations in BP control should be reconsidered to take into account patients’ chronic pain. Further research is needed of moderation effects of different antihypertensive manipulations on pain to improve pain management in these patients. (Source: Journal of Hypertension)
Source: Journal of Hypertension - April 3, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Cross-Cultural Adaptation, Reliability and Validity of the Turkish Version of Patient-Specific Functional Scale in Patients with Chronic Neck Pain.
Authors: Yalçinkaya G, Kara B, Arda MN Abstract BACKGROUND/AIM: Current clinical guidelines recommend to use both clinical and self-reported measurements for evaluation of chronic neck pain. Among the self-reported outcomes, Neck Disability Index and Patient Specific Functional Scale are the most widely used and recommended instruments. The purpose of our study was to determine the test-retest reliability and validity of Patient Specific Functional Scale which was not validated in Turkish language previously. MATERIALS AND METHODS: Translation and adaptation process had conducted according to the Beaton ...
Source: Turkish Journal of Medical Sciences - April 3, 2020 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Neck Muscle Stiffness Measured With Shear Wave Elastography in Women With Chronic Nonspecific Neck Pain
Journal of Orthopaedic&Sports Physical Therapy,Volume 50, Issue 4, Page 179-188, April 2020. (Source: The Journal of Orthopaedic and Sports Physical Therapy)
Source: The Journal of Orthopaedic and Sports Physical Therapy - April 3, 2020 Category: Physiotherapy Authors: Angela V. Dieterich Utku Şükrü Yavuz Frank Petzke Antoine Nordez Deborah Falla Source Type: research

Enhanced recovery after spine surgery —a multinational survey assessing surgeons’ perspectives
AbstractBackgroundEnhanced Recovery After Surgery (ERAS) is the object of numerous publications in various surgical fields. Still, its value in spine surgery is not as recognized as it is in other surgical domains. Our aim was to report neurosurgeons ’ opinions about ERAS in spine surgery.MethodsFrom December 2019 to January 2020, members of the European Association of Neurosurgical Societies were asked to complete an online questionnaire regarding ERAS in spine surgery.ResultsN = 234 participants responded to the survey (60% spine neurosurgeons; 22.6% working in private practice). Thirty-two percent re...
Source: Acta Neurochirurgica - April 3, 2020 Category: Neurosurgery Source Type: research

Delayed stabilisation of dynamically unstable syndesmotic injuries results in worse functional outcomes
This study aimed to assess clinical outcomes in patients who required syndesmosis fixation in the presence of arthroscopically proven instability, the hypothesis being that a delay to treatment would be associated with worse function.MethodA retrospective cohort study was performed of patients with dynamic instability requiring fixation between the years of 2010 –2016. The procedures were performed by two foot and ankle fellowship trained orthopaedic surgeons, over three hospital sites. Patients were classified into three groups based on the time since injury to surgery, acute syndesmotic injury (  6 mont...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - April 3, 2020 Category: Orthopaedics Source Type: research

How do the attitudes, confidence, knowledge and understanding differ in pre-registration healthcare students towards treating people with chronic pain: an observational, cross-sectional study
. (Source: European Journal of Physiotherapy)
Source: European Journal of Physiotherapy - April 3, 2020 Category: Rehabilitation Authors: Sean Paul Carroll Nathan Augeard Jacob Tennant Christopher Seenan Source Type: research

The projections from the anterior cingulate cortex to the nucleus accumbens and ventral tegmental area contribute to neuropathic pain-evoked aversion in rats.
Abstract Although the anterior cingulate cortex (ACC) plays a vital role in neuropathic pain-related aversion, the underlying mechanisms haven't been fully studied. The mesolimbic dopamine system encodes reward and aversion, and participates in the exacerbation of chronic pain. Therefore, we investigated whether the ACC modulates aversion to neuropathic pain via control of the mesolimbic dopamine system, in a rat model of chronic constriction injury (CCI) to the sciatic nerve. Using anterograde and retrograde tracings, we confirmed that a subgroup of ACC neurons projected to the nucleus accumbens (NAc) and ventral...
Source: Neurobiology of Disease - April 3, 2020 Category: Neurology Authors: Gao SH, Shen LL, Wen HZ, Zhao YD, Chen PH, Ruan HZ Tags: Neurobiol Dis Source Type: research

Repetitive transcranial magnetic stimulation in traumatic brain injury: evidence from animal and human studies.
Abstract We provide here the first systematic review on the studies dealing with repetitive transcranial magnetic stimulation (rTMS) for traumatic brain injury (TBI) in animals and humans. Several experimental studies in animal models have explored with promising results the use of rTMS to enhance neuroprotection and recovery after TBI. However, there are surprisingly few studies that have obtained substantial evidence regarding effects of rTMS in humans with TBI, many of them are case reports investigating the heterogeneous conditions linked to TBI. The most studies have investigated the effects of rTMS in subjec...
Source: Brain Research Bulletin - April 3, 2020 Category: Neurology Authors: Nardone R, Sebastianelli L, Versace V, Brigo F, Golaszewski S, Manganotti P, Saltuari L, Trinka E Tags: Brain Res Bull Source Type: research

Bilateral fibular head prominence: A case report of bilateral chronic knee pain
Publication date: Available online 10 March 2020Source: Current Medicine Research and PracticeAuthor(s): Deepak Kumar Singhal, Brajesh Nandan, Siddharth Agrawal (Source: Current Medicine Research and Practice)
Source: Current Medicine Research and Practice - April 2, 2020 Category: General Medicine Source Type: research

Concomitant ankle instability has a negative impact on the quality of life in patients with osteochondral lesions of the talus: data from the German Cartilage Registry (KnorpelRegister DGOU)
ConclusionPatients with OCLT with concomitant CAI differ from those without concomitant CAI according to demographic and lesion-related factors. The additional presence of CAI worsens the quality of life of patients with OCLT. Patients with OCLT should be examined for concomitant CAI, so that if CAI is present, it can be integrated into the treatment concept.Level of evidenceIV. (Source: Knee Surgery, Sports Traumatology, Arthroscopy)
Source: Knee Surgery, Sports Traumatology, Arthroscopy - April 2, 2020 Category: Orthopaedics Source Type: research

IJERPH, Vol. 17, Pages 2417: The Implementation Process of Nurse Prescribing in Poland —A Descriptive Study
IJERPH, Vol. 17, Pages 2417: The Implementation Process of Nurse Prescribing in Poland—A Descriptive Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17072417 Authors: Zimmermann Cieplikiewicz Wąż Gaworska-Krzemińska Olczyk The study aimed to investigate the situation of nurse prescribing, introduced in Poland in 2016, by analyzing the opinions of nurses, expected to be influential on nurses’ actual practices, in response to legislative change to enable nurses to prescribe and comparing this with actual nurse prescribing behaviours during...
Source: International Journal of Environmental Research and Public Health - April 2, 2020 Category: Environmental Health Authors: Zimmermann Cieplikiewicz W ąż Gaworska-Krzemi ńska Olczyk Tags: Article Source Type: research

Treatment of Psoriasis with Secukinumab in Challenging Patient Scenarios: A Review of the Available Evidence
AbstractPsoriasis (PsO) is a common, systemic, chronic, inflammatory disease characterized by key clinical symptoms, including itching, pain, and scaling. PsO is associated with a high prevalence of comorbidities, including other autoimmune diseases and malignancies. Furthermore, special populations, such as pregnant, pediatric, and elderly patients, and those with erythrodermic PsO, are challenging to treat and require tightly monitored disease and treatment management. Because certain populations have demographic or clinical characteristics that can affect the presentation of PsO and complicate treatment responses, these...
Source: Dermatology and Therapy - April 2, 2020 Category: Dermatology Source Type: research

Identification of intrinsic and reflexive contributions to trunk stabilization in patients with low back pain: a case –control study
ConclusionTrunk stabilization differs between LBP patients and controls, with the same perturbations causing less trunk movement in patients, due to stronger reflexes. We interpret these changes as reflecting protective behavior.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 2, 2020 Category: Orthopaedics Source Type: research

Acetylcholinesterase inhibitor exposures as an initiating factor in the development of Gulf War Illness, a chronic neuroimmune disorder in deployed veterans.
Abstract Gulf War Illness (GWI) is a chronic multi-symptom disorder, characterized by symptoms such as fatigue, pain, cognitive and memory impairment, respiratory, skin and gastrointestinal problems, that is experienced by approximately one-third of 1991 Gulf War veterans. Over the nearly three decades since the end of the war, investigators have worked to elucidate the initiating factors and underlying causes of GWI. A significant portion of this research has indicated a strong correlation between GWI and exposure to a number of different acetycholinesterase inhibitors (AChEIs) in theater, such as sarin and cyclo...
Source: Neuropharmacology - April 2, 2020 Category: Drugs & Pharmacology Authors: Michalovicz LT, Kelly KA, Sullivan K, O'Callaghan JP Tags: Neuropharmacology Source Type: research

The Association of Preoperative Characteristics with Reintervention Risk in Patients Undergoing Revascularization for Chronic Limb-Threatening Ischemia (Iida. Reintervention Risk in CLTI).
CONCLUSIONS: The current study identified preoperative characteristics associated with an increased risk of reintervention. No preoperative characteristics had any significant interactions with EVT or surgical reconstruction. PMID: 32224557 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 1, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Peripheral Neuropathy Associated with Hypereosinophilic Syndrome: A Clinical Therapeutic Success with Capsaicin 8% Patch.
Authors: Ruivo EFM, Gestosa SVS, Mulenas NME, Lares AMG Abstract Neuropathic pain is defined as a direct consequence of an injury or disease that affects the somatosensory system, which may affect 7 to 10% of the world population. Regardless of its origin, it is often described as disabling, chronic, difficult to treat and with a noticeable impact on patients' quality of life. This case report describes a patient with peripheral polyneuropathy associated with hypereosinophilic syndrome, a medical condition scarcely described in literature. Capsaicin 8% patches therapy, never mentioned before in the literature in su...
Source: Journal of Pain and Palliative Care Pharmacotherapy - April 1, 2020 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

The efficacy and safety of cooled-radiofrequency neurotomy in the treatment of chronic thoracic facet (zygapophyseal) joint pain: A retrospective study
Anatomic course of medial branches in the thoracic spine is significantly different. Cooled RFA (CRFA) is a newer technique that can create a larger spherical lesion with a potential to compensate for the anatomic variability of the medial branches in the thoracic spine. Our retrospective study aimed to investigate the efficacy and the adverse effects of the CRFA in the treatment of thoracic facet-related pain. For this retrospective study, we evaluated 40 CRFA performed on 23 patients. The patients with diagnosis of thoracic facet joint-related pain underwent CRFA. Pain scores in numeric rating scale (NRS) were recorded ...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Effect of auriculotherapy on chronic low back pain: A protocol for systematic review and meta-analysis
Conclusion: This study will provide new evidence to evaluate the effectiveness and side effects of AT on CLBP. Because the data is not personalized, no formal ethical approval is required. PROSPERO registration number: CRD42020151584. (Source: Medicine)
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Co-occurrence of PML-RARA gene fusion, chromosome 8 trisomy, and FLT3 ITD mutation in a young female patient with de novo acute myeloid leukemia and early death: A CARE case report
We present the case of a young female (20 years old) patient, who presented at the emergency department 5 months after giving birth to her first child, complaining of asthenia, fatigue, general musculoskeletal pain, and fever (38°C), symptoms having been present for the previous 6 days. The patient denied any chronic diseases in her medical and family history. Diagnosis: Laboratory analysis revealed severe pancytopenia. Cytogenetic and molecular analyzes revealed chromosomal abnormalities (trisomy 8), PML-RARA gene fusion, and fms-like tyrosine kinase 3 (FLT3) gene mutation. The immunophenotypic analysis was also su...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Chronic Pain After Gastric Bypass: Another Argument to Support Mesenteric Windows Closure
Chronic pain is frequent after Roux-en-Y gastric bypass (RYGB). Recurrent internal hernias (IHs) may be responsible for chronic abdominal pain. Physical examination and computed tomography are often inconclusive. This observational retrospective study describes 11 patients who underwent elective laparoscopy for post-RYGB chronic abdominal pain of undetermined etiology after noninvasive investigations and failure of conservative treatment. Open intermesenteric and/or Peterson spaces were found in all cases; IH was present in 6 cases. Nine patients were totally relieved from symptoms after mesenteric windows closure; substan...
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - April 1, 2020 Category: Surgery Tags: Original Articles Source Type: research

Attention-Deficit/Hyperactivity Disorder and Chronic Pain
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2020 Category: Psychiatry & Psychology Tags: LETTERS TO THE EDITOR Source Type: research

Erythema Ab Igne in an Adolescent With Chronic Pain: An Alarming Cutaneous Eruption From Heat Exposure
Erythema ab igne (EAI) is a cutaneous finding caused by prolonged heat exposure and is characterized by a reticular, brownish-pigmented, often telangiectatic dermatosis. The eruption is reminiscent of livedo reticularis, which is typically seen in the setting of a number of rheumatologic conditions, most prominently vasculitis. Identification of key features distinguishing EAI from livedo reticularis can aid in the diagnosis of EAI and correct elucidation of the underlying etiology. Our patient presented with heating pad–induced EAI in the setting of chronic pain. Only 6 other pediatric cases of EAI associated with h...
Source: Pediatric Emergency Care - April 1, 2020 Category: Emergency Medicine Tags: Illustrative Cases Source Type: research

Lumbopelvic motor control function between patients with chronic low back pain and healthy controls: a useful distinguishing tool: The STROBE study
Although lumbopelvic stability exercise improves lumbopelvic motor control function in patients with chronic low back pain (CLBP), the difference in lumbopelvic motor control function between the patients with CLBP and the healthy controls is unclear. The purpose of this study was to compare lumbopelvic motor control function between patients with CLBP and healthy controls and to determine the prevalence of CLBP according to core stability function. For this study, 278 participants were recruited, including patients with CLBP (n = 137) and healthy controls (n = 141). The participants performed a core stability fun...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Case report of an unusual presentation of Staphylococcus aureus induced toxic shock syndrome/hyperimmunoglobulinemia E syndrome
Rationale: Toxic shock syndrome (TSS) typically is an acute onset multi-organ infection caused by TSS toxin-1 producing Staphylococcus aureus. Herein we describe a highly unusual case report. Patient concerns: A male patient self-referred to the University of Minnesota Hospital with a chronic history of S aureus infection with accompanying fever, hypotension, and nonhealing, football-sized lesion on his leg. Diagnosis: An unusual case presentation of TSS/hyperimmunoglobulin E syndrome is described. The patient had a leg wound from which TSS toxin-1 S aureus was isolated. The patient exhibited characteristic skewing...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

The efficacy of extracorporeal shock wave for chronic musculoskeletal pain conditions: A protocol of systematic review and meta-analysis of randomized controlled trials
Conclusion: It can provide the updated evidence which is of great importance for patients, clinical practice and health related policy maker in ESWT treating CMPC. (Source: Medicine)
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Colchicine therapy for deep vein thrombosis in a patient with vascular-type Behçet disease: A case report
Rationale: Behçet Disease (BD) is a chronic inflammatory vasculitis with thrombogenicity and multisystem involvement. Deep vein thrombosis (DVT) in the lower extremities is the most frequent manifestation of vascular involvement in BD. The causes of thrombosis vary widely and include congenital predisposition and acquired factors, but of all the thrombosis, the cause is rarely BD. Furthermore, there are few reports of treatment for thrombosis in BD. Patient concerns: We herein describe the case of an Asian male patient aged 40 years, admitted to our hospital for left leg pain, edema, and swelling. Diagnoses: ...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Severe vaso-occlusive lupus retinopathy in the early stage of a pediatric patient with systemic lupus erythematosus: a case report
Conclusions: An early diagnosis and the prompt therapeutic measures are necessary to prevent sight-threatening consequences, especially in pediatric patients with SLE. (Source: Medicine)
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Immediate Effects of Exercise and Behavioral Interventions for Pelvic Floor Dysfunction and Lumbopelvic Pain
Source: Journal of Womens Health Physical Therapy - April 1, 2020 Category: Physiotherapy Tags: Research Reports Source Type: research

“I Just Beared Through It”: Southern US Christian Women's Experiences of Chronic Dyspareunia
Source: Journal of Womens Health Physical Therapy - April 1, 2020 Category: Physiotherapy Tags: Research Report Source Type: research

Retroperitoneal fibromatosis presenting as a mesenteric mass: A case report
Rationale: Fibromatoses or desmoid tumors are relatively rare tumors derived from the musculoaponeurotic system. This tumor has no specific clinical symptoms and it is sometimes misdiagnosed as other diseases such as gastrointestinal stromal tumors (GISTs). Patient concerns: A 28-year-old man visited Peking Union Medical College for a tangible abdominal mass without abdominal pain or distention. Diagnoses: Considering the imaging characteristics and clinical manifestation, this mass was primarily diagnosed as GIST before surgery. During the surgery, the occupancy was found under the ileocecal mesentery, with grayis...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Pain acceptance levels of patients with chronic pain
This study was conducted with the aim of determining pain acceptance levels in patients with chronic pain attending an algology outpatients’ department. The research was conducted as a descriptive and cross-sectional study. The population of the study consisted of 97 patients with chronic pain who attended the Algology Outpatients’ Department of the Health Implementation and Research Center of Bursa Uludağ University. A Patient Description Form and a Chronic Pain Acceptance Questionnaire (CPAQ) were used to collect research data. The participants’ mean sub-score for accomplishing activities by patients...
Source: Medicine - April 1, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Management of Quebec Platelet Disorder for Cervical Facet Injections in the Outpatient Setting: A Case Report
We report a patient with QPD and extensive history of postprocedural bleeding complications (PPBCs) who presented with chronic cervical facet pain. After consulting a hematologist and administering antifibrinolytic agent with platelet transfusions, the patient underwent medial branch nerve blocks (MBNBs) followed by radiofrequency ablation (RFA) without experiencing PPBCs. A comprehensive team approach is critical to maximize patient safety when performing an ISP in such a population. (Source: A&A Case Reports)
Source: A&A Case Reports - April 1, 2020 Category: Anesthesiology Tags: Case Report Source Type: research

Spinal Cord Stimulation for Neurogenic Thoracic Outlet Syndrome: A Case Report
Despite conservative and surgical treatments, patients with neurogenic thoracic outlet syndrome can develop debilitating chronic pain of the shoulder and arm. Here we report a case of a patient who failed medical treatment, surgical resection of the first rib, and subsequent resection of rib regrowth with partial excision of a hypertrophied middle scalene muscle. Ultimately, this patient was successfully treated with spinal cord stimulation with dramatic pain relief and remarkable functional improvement for more than 3 years. This first report provides hope for those who suffer from this debilitating syndrome. (Source: A&A Case Reports)
Source: A&A Case Reports - April 1, 2020 Category: Anesthesiology Tags: Case Report Source Type: research

Intermediate Cervical Plexus Block: A Novel Intervention in the Management of Refractory Chronic Neck and Upper Back Pain Following Whiplash Injury: A Case Report
Chronic neck and upper back pain occurs in 40%–60% of patients that suffer whiplash injury. Increasing evidence points to a dysfunction of the cervical and thoracic muscles as the predominant cause of persistent pain in this cohort. Response to standard management including physiotherapy, psychotherapy, medications, and acupuncture are often inadequate. As a result, there is significant functional impairment leading to excessive health care costs. The authors present a novel treatment, intermediate cervical plexus block with depot steroids, in 3 patients presenting with refractory chronic neck and upper back pain fro...
Source: A&A Case Reports - April 1, 2020 Category: Anesthesiology Tags: Case Report Source Type: research

Breast Implant Illness: A Biofilm Hypothesis
Source: Plastic and Reconstructive Surgery Global Open - April 1, 2020 Category: Cosmetic Surgery Tags: Original Article Source Type: research

Targeted Muscle Reinnervation following Breast Surgery: A Novel Technique
Source: Plastic and Reconstructive Surgery Global Open - April 1, 2020 Category: Cosmetic Surgery Tags: Ideas and Innovations Source Type: research

Hip Muscle Strengthening for Knee Osteoarthritis: A Systematic Review of Literature
Conclusion: The current review identified strong, high-quality evidence to recommend hip muscle strengthening in the conservative management of persons with knee OA. Further research is needed to establish the underlying mechanisms for the clinical benefits. (Source: Journal of Geriatric Physical Therapy)
Source: Journal of Geriatric Physical Therapy - April 1, 2020 Category: Physiotherapy Tags: Systematic Reviews Source Type: research

Chronic Pain One to Five Years after Heart Transplantation
We know that pain has far-reaching detrimental effects across various life-domains and also affects health related quality of life after solid organ transplantation. However, the extent to which heart recipients experience chronic bodily pain in the years after heart transplantation is a neglected field. Pain is reported to be a major problem after other types of solid organ transplantation. Neither the prevalence nor consequences of chronic pain after heart transplantation have been fully explored or understood. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2020 Category: Transplant Surgery Authors: M. Dalvindt, S. Nozhoor, A. Kisch, A. Forsberg Tags: (1281) Source Type: research

Intraoperative Methadone: New Use for an Old Drug
Inadequately managed postsurgical pain impacts morbidity, mortality, and health care costs. More than 75% of surgical patients in the United States experience moderate, severe, or extreme postoperative pain.1,2 Despite efforts to control pain during and immediately after surgery with agents such as local anesthetics, opiates, gabapentinoids, acetaminophen, and nonsteroidal anti-inflammatory agents, pain often persists. The risk of developing chronic postoperative pain has been correlated to the intensity of acute postoperative pain. (Source: Journal of PeriAnesthesia Nursing)
Source: Journal of PeriAnesthesia Nursing - April 1, 2020 Category: Nursing Authors: Rachel C. Wolfe Tags: Pharmacology Facts Source Type: research

The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis
AbstractPurposeCannabis has been used for thousands of years in many cultures for the treatment of several ailments including pain. The benefits of cannabis are mediated largely by cannabinoids, the most prominent of which are tetrahydrocannabinol (THC) and cannabidiol (CBD). As such, THC and/or CBD have been investigated in clinical studies for the treatment of many conditions including neuropathic pain and acute or chronic inflammation. While a plethora of studies have examined the biochemical effects of purified THC and/or CBD, only a few have focused on the effects of full-spectrum cannabis plant extract. Accordingly, ...
Source: Inflammation Research - April 1, 2020 Category: Research Source Type: research

“So, I try not to go…” Acute-on-chronic breathlessness and presentation to the emergency department: in-depth interviews with patients, carers and clinicians
People with acute-on-chronic breathlessness due to cardiorespiratory conditions frequently present to the emergency department (ED) causing burden for the person concerned, their carers and emergency services. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 1, 2020 Category: Palliative Care Authors: Ann Hutchinson, Kathleen Galvin, Miriam J. Johnson Tags: Original Article Source Type: research