Palindromic rheumatism following COVID-19 infection evolved to rheumatoid arthritis after COVID-19 reinfection
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1410-1412. Epub 2021 Nov 25.ABSTRACTA 33-year-old woman developed palindromic rheumatism (PLR) several weeks following an infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Three months later, she developed full blown seropositive rheumatoid arthritis (RA) following COVID-19 reinfection. Although the occurrence of the joint diseases and the COVID-19 infections maybe fortuitous, knowing the enormous effects of COVID-19 infection on the human immune system, it is difficult to ignore the temporal relationship between the appearance of PLR after the first COVID-1...
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Eli Ben-Chetrit Eldad Ben-Chetrit Source Type: research

One year in review 2021: axial spondyloarthritis
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1272-1281. Epub 2021 Nov 25.ABSTRACTAxial spondyloarthritides (axSpA) are a group of systemic inflammatory rheumatic diseases with a broad spectrum of clinical manifestations and typical imaging features, rarely accompanied by laboratory abnormalities. They can be classified into a so-called non-radiographic form (nr-axSpA), unlike the radiographic one, because magnetic resonance imaging may show specific inflammatory lesions when conventional radiology is not able to highlight them. Inflammatory involvement of the axial skeleton tends to associate typically with new bone formation an...
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Chiara Cardelli Sara Monti Riccardo Terenzi Linda Carli Source Type: research

Mixed cryoglobulinaemia and hepatitis C virus: a paradigm of a virus-related autoimmune and lymphoproliferative disorder
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1265-1268. Epub 2021 Nov 25.NO ABSTRACTPMID:34842134 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Clodoveo Ferri Stefano Bombardieri Source Type: research

Palindromic rheumatism following COVID-19 infection evolved to rheumatoid arthritis after COVID-19 reinfection
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1410-1412. Epub 2021 Nov 25.ABSTRACTA 33-year-old woman developed palindromic rheumatism (PLR) several weeks following an infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Three months later, she developed full blown seropositive rheumatoid arthritis (RA) following COVID-19 reinfection. Although the occurrence of the joint diseases and the COVID-19 infections maybe fortuitous, knowing the enormous effects of COVID-19 infection on the human immune system, it is difficult to ignore the temporal relationship between the appearance of PLR after the first COVID-1...
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Eli Ben-Chetrit Eldad Ben-Chetrit Source Type: research

One year in review 2021: axial spondyloarthritis
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1272-1281. Epub 2021 Nov 25.ABSTRACTAxial spondyloarthritides (axSpA) are a group of systemic inflammatory rheumatic diseases with a broad spectrum of clinical manifestations and typical imaging features, rarely accompanied by laboratory abnormalities. They can be classified into a so-called non-radiographic form (nr-axSpA), unlike the radiographic one, because magnetic resonance imaging may show specific inflammatory lesions when conventional radiology is not able to highlight them. Inflammatory involvement of the axial skeleton tends to associate typically with new bone formation an...
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Chiara Cardelli Sara Monti Riccardo Terenzi Linda Carli Source Type: research

Mixed cryoglobulinaemia and hepatitis C virus: a paradigm of a virus-related autoimmune and lymphoproliferative disorder
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1265-1268. Epub 2021 Nov 25.NO ABSTRACTPMID:34842134 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Clodoveo Ferri Stefano Bombardieri Source Type: research

Palindromic rheumatism following COVID-19 infection evolved to rheumatoid arthritis after COVID-19 reinfection
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1410-1412. Epub 2021 Nov 25.ABSTRACTA 33-year-old woman developed palindromic rheumatism (PLR) several weeks following an infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Three months later, she developed full blown seropositive rheumatoid arthritis (RA) following COVID-19 reinfection. Although the occurrence of the joint diseases and the COVID-19 infections maybe fortuitous, knowing the enormous effects of COVID-19 infection on the human immune system, it is difficult to ignore the temporal relationship between the appearance of PLR after the first COVID-1...
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Eli Ben-Chetrit Eldad Ben-Chetrit Source Type: research

One year in review 2021: axial spondyloarthritis
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1272-1281. Epub 2021 Nov 25.ABSTRACTAxial spondyloarthritides (axSpA) are a group of systemic inflammatory rheumatic diseases with a broad spectrum of clinical manifestations and typical imaging features, rarely accompanied by laboratory abnormalities. They can be classified into a so-called non-radiographic form (nr-axSpA), unlike the radiographic one, because magnetic resonance imaging may show specific inflammatory lesions when conventional radiology is not able to highlight them. Inflammatory involvement of the axial skeleton tends to associate typically with new bone formation an...
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Chiara Cardelli Sara Monti Riccardo Terenzi Linda Carli Source Type: research

Mixed cryoglobulinaemia and hepatitis C virus: a paradigm of a virus-related autoimmune and lymphoproliferative disorder
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1265-1268. Epub 2021 Nov 25.NO ABSTRACTPMID:34842134 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 29, 2021 Category: Rheumatology Authors: Clodoveo Ferri Stefano Bombardieri Source Type: research

Primary Sj ögren's syndrome with minimal change disease: case series and literature review
Clin Exp Rheumatol. 2021 Nov 11. Online ahead of print.NO ABSTRACTPMID:34796835 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Jiaxin Lang Xiaoxiao Shi Yixin Ma Linfeng Zou Yunyun Fei Limeng Chen Source Type: research

Identifying mindfulness and acceptance as mediators between negative affect, functional disability and emotional distress in patients with fibromyalgia
Clin Exp Rheumatol. 2021 Nov 18. Online ahead of print.ABSTRACTOBJECTIVES: Fibromyalgia (FM) is a prevalent disabling condition characterised by chronic widespread pain. It is considered a complex illness in which the prognosis is conditioned by affective and cognitive mediators still largely unknown in FM. To investigate the correlation between psychological variables (acceptance, negative affect, and mindfulness) and functional disability or physical impact, anxiety/depression symptoms and emotional distress, and also to evaluate the mediating role of acceptance and mindfulness between negative affect, physical impact, a...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Sara Maurel Naia S áez-Francàs Natalia Calvo Jos é Alegre-Martín Jes ús Castro-Marrero Source Type: research

Blood chemokine levels are markers of disease activity but not predictors of remission in early rheumatoid arthritis
CONCLUSIONS: In patients with untreated eRA, plasma levels of several chemokines correlate with disease activity at baseline but cannot predict remission after 24 weeks of treatment with methotrexate combined with prednisolone, anti‑TNF, CTLA‑4Ig or anti‑IL6R.PMID:34796837 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Jonathan Aldridge Anna-Carin Lundell Kerstin Andersson Linda Mark Merete Lund Hetland Mikkel Østergaard Till Uhlig Marte Schrumpf Heiberg Espen A Haavardsholm Michael Nurmohamed Jon Lampa Dan Nordstr öm Kim H ørslev-Petersen Bjorn Gudbjornsson Gerdur G Source Type: research

Idiopathic retroperitoneal fibrosis: clinical features, treatment modalities, relapse rate in Greek patients and a review of the literature
CONCLUSIONS: Relapse occurred in one-fifth of patients independently of the initial clinical/radiographic presentation or treatment used. iRPF patients with baseline elevated serum IgG4 levels have a higher relapse rate.PMID:34796838 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Evangelia Zampeli Aliki I Venetsanopoulou Sophia Christaki Ourania D Argyropoulou Kyriaki A Boki Menelaos N Manoussakis Foteini N Skopouli Athanasios G Tzioufas Haralampos M Moutsopoulos Source Type: research

Prediction of the intolerance or non-responder to Janus kinase inhibitors in patients with rheumatoid arthritis: a preliminary retrospective study with integrative cluster analysis
CONCLUSIONS: A subpopulation of RA patients with a combination of the following three components, seronegativity, advanced joint destruction and absence of RA-ILD, was identified as being prone to JAKis-IR.PMID:34796839 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Masanari Sugawara Yuichiro Fujieda Atsushi Noguchi Shun Tanimura Yuka Shimizu Ikuma Nakagawa Masaru Yoshimura Nobuya Abe Michihito Kono Masaru Kato Kenji Oku Olga Amengual Isao Yokota Hiroki Takahashi Tatsuya Atsumi Source Type: research

Outcomes after lung transplantation among Chinese patients with connective tissue disease-associated interstitial lung disease and pulmonary hypertension: a retrospective cohort study
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.ABSTRACTOBJECTIVES: The present study aimed to compare the post-lung transplant survival and complications of connective tissue disease (CTD)-related interstitial lung disease (ILD) and/or pulmonary arterial hypertension with idiopathic pulmonary fibrosis (IPF).METHODS: The clinical data of patients with CTD-ILD or IPF who received lung transplantation between 2015 and 2020 were retrospectively reviewed. Cumulative survival rates after transplantation were estimated using the Kaplan-Meier method.RESULTS: The study included 31 patients with confirmed CTD-ILD and 98 with ...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Chunrong Ju Qiaoyan Lian Ao Chen Xin Xu Jianheng Zhang Qun Luo Danxia Huang Rongchang Chen Jianxing He Source Type: research

Flexion contracture is associated with knee joint degeneration on magnetic resonance imaging: data from the Osteoarthritis Initiative
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.ABSTRACTOBJECTIVES: Knee osteoarthritis (OA) is often accompanied by a flexion contracture (FC), resulting in worse clinical outcomes. Our objective was to determine associations between knee FC and specific regional and/or structural alterations on magnetic resonance imaging (MRI) using the Osteoarthritis Initiative (OAI).METHODS: 600 knees from the Foundation for the National Institutes of Health sub-study of the OAI were included. Knee extension was measured with a goniometer and FC was defined as inability to extend the knee to 0°. Structural alterations within ...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Mark T Campbell Guy Trudel Philip G Conaghan Katherine Reilly Robert J Feibel Dennis McGonagle Source Type: research

Incidence and risk factors of COVID-19 in patients with vasculitis in the first year of the pandemic: a Danish nationwide cohort study
Clin Exp Rheumatol. 2021 Oct 28. Online ahead of print.NO ABSTRACTPMID:34796842 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Salome Kristensen Ren é Cordtz Kirsten Duch Jesper Lindhardsen Christian Torp-Pedersen Lene Dreyer Source Type: research

Intra-articular osteoid osteoma mimicking juvenile psoriatic dactylitis
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796843 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Luciana Breda Giulia Sassano Saverio La Bella Cristina Gentile Lorenzo Sansone Francesco Chiarelli Source Type: research

Clinical implications of fever at diagnosis in polymyalgia rheumatica: an age- and sex-matched case control study of 120 patients. Reply to Milchert et al. and Manzo et al
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796844 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Albrecht Betrains Lennert Boeckxstaens Koen Van Laere Steven Vanderschueren Daniel Blockmans Source Type: research

Work productivity and activity impairment in patients with primary Sj ögren's syndrome
CONCLUSIONS: We found a compromise in all WPAI domains. Arthritis, xerostomia and depression were associated significantly and independently with ADL impairment. Deterioration in ADL was greater in patients treated in public centres. Considering these aspects will allow a better understanding of patients who suffer from this disease.PMID:34796845 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Marisel Vanesa Bejarano Felix Romanini Antonio Catal án Pellet Marta N Mamani Silvia Papasidero Julia Demarchi Cecilia A Asnal C E Crow Alejandro Nitsche L Encinas F Caeiro Carla A Gobbi Eduardo Albiero Andrea G ómez R Águila Maldonado Mercedes Garc í Source Type: research

Fever at diagnosis as a confounding factor in patients with polymyalgia rheumatica. Messages from primary care. Comments on Betrains et al
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796846 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Ciro Manzo Maria Natale Source Type: research

Clinical heterogeneities and prognoses of patients with myositis specific antibody negative dermatomyositis: a retrospective study in China
CONCLUSIONS: Through cluster analysis, different clinical phenotypes of MSA negative DM patients were determined. The prognoses of the two subgroups were different in terms of survival rate and cause of death.PMID:34796847 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Shanshan Li Suhao Gao Qingning Chen Junfeng Han Ling Zhang Yongpeng Ge Yu Zuo Jianghui Duan Xin Lu Guochun Wang Source Type: research

Is there a potential for therapeutic drug monitoring of subcutaneously administered tocilizumab in patients with rheumatoid arthritis in daily practice?
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796848 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Zohra Layegh Femke Hooijberg Carla Bastida Alwin D R Huitema Theo Rispens Gertjan Wolbink Source Type: research

Implications of fever on erythrocyte sedimentation rate but not on C-reactive protein concentrations at the time of diagnosis of polymyalgia rheumatica. Comments on Betrains et al
Clin Exp Rheumatol. 2021 Nov 11. Online ahead of print.NO ABSTRACTPMID:34796849 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Marcin Milchert Alberto Castagna Ciro Manzo Marek Brzosko Source Type: research

Dipeptidyl peptidase 4/CD26 expression in human idiopathic inflammatory myopathies reveals skeletal muscle injury and vascular inflammation
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.ABSTRACTOBJECTIVES: We performed a retrospective and prospective observational study to investigate whether the T lymphocyte activation antigen dipeptidyl peptidase 4 (DPP4)/CD26 is expressed in the skeletal muscle of patients with idiopathic inflammatory myopathies (IIM) and whether its expression offers clues to understand the events taking place in the tissue.METHODS: CD26 expression in the muscle, evaluated by immunofluorescence, was assessed in 32 patients with IIM and 5 healthy controls and compared among patients with dermatomyositis (DM), immune-mediated necroti...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Rebecca De Lorenzo Antonella Monno Clara Sciorati Isabella Lorenzetti Silvia Cavalli Francesco Bonomi Stefano Carlo Previtali Patrizia Rovere-Querini Source Type: research

Development and performance of the Clinical Trials ESSDAI (ClinTrialsESSDAI), consisting of frequently active clinical domains, in two randomised controlled trials in primary Sj ögren's syndrome
CONCLUSIONS: The ClinTrialsESSDAI, consisting of six frequently active clinical domains of the ESSDAI, shows closely similar responsiveness and discrimination between treatment groups compared to the ClinESSDAI and ESSDAI. Therefore, this ClinTrialsESSDAI is not preferable to ClinESSDAI and ESSDAI for use as primary endpoint. A composite endpoint combining response at multiple clinically relevant items seems more suitable as primary study endpoint in pSS.PMID:34796851 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Liseth de Wolff Suzanne Arends Elena Pontarini Michele Bombardieri Simon J Bowman Hendrika Bootsma Source Type: research

Treatment of refractory hypocomplementaemic urticarial vasculitis syndrome progressing to systemic lupus erythematosus with belimumab
Clin Exp Rheumatol. 2021 Nov 17. Online ahead of print.NO ABSTRACTPMID:34796852 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Larissa Valor-M éndez Georg Schett Bernhard Manger Source Type: research

The negative impact of undiagnosed depression in axial spondyloarthropathy
Clin Exp Rheumatol. 2021 Oct 21. Online ahead of print.NO ABSTRACTPMID:34796853 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Sinead Maguire Phil Gallagher Finbar O'Shea Source Type: research

Sonoelastography of salivary glands for diagnosis and clinical evaluation in primary Sj ögren's syndrome
CONCLUSIONS: Sonoelastography, performed simultaneously with ultrasonography, is an additional tool for the assessment of the salivary glands in patients with pSS. The elasticity is closely associated with disease duration.PMID:34796854 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Xia Zhang Shanshan Zhang Ruiling Feng Haihong Yao Sumei Tang Jing He Source Type: research

Differences in presentation between paediatric- and adult-onset primary Sj ögren's syndrome patients
Clin Exp Rheumatol. 2021 Nov 10. Online ahead of print.ABSTRACTOBJECTIVES: Primary Sjögren's syndrome (pSS) is a rare disease in paediatric patients. Presenting symptoms differ from those in adult patients. The aim of this study was to evaluate presenting symptoms, classification criteria and clinical assessments, including salivary gland ultrasonography (SGUS), at disease onset in paediatric and adult patients with pSS.METHODS: Data of 23 paediatric- and 33 adult-onset patients with pSS were obtained from our standardised multidisciplinary REpSULT and RESULT cohorts, respectively. Clinical, patient-reported, serologi...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Geertje E Legger Margit B Erdtsieck Liseth de Wolff Alja J Stel Leonoor I Los Gwenny M Verstappen Fred K L Spijkervet Arjan Vissink Bert van der Vegt Frans G M Kroese Wineke Armbrust Suzanne Arends Hendrika Bootsma Source Type: research

Hypergammaglobulinaemia predicts glandular and extra-glandular damage in primary Sj ögren's syndrome: results from the KISS cohort study
CONCLUSIONS: Persistent hypergammaglobulinaemia was associated with salivary gland and solid organ damage. Decreased IgG may attenuate progression to solid organ dysfunction.PMID:34796856 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Jung Hee Koh Youngjae Park Jennifer Lee Sung-Hwan Park Seung-Ki Kwok Source Type: research

Primary Sj ögren's syndrome with minimal change disease: case series and literature review
Clin Exp Rheumatol. 2021 Nov 11. Online ahead of print.NO ABSTRACTPMID:34796835 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Jiaxin Lang Xiaoxiao Shi Yixin Ma Linfeng Zou Yunyun Fei Limeng Chen Source Type: research

Identifying mindfulness and acceptance as mediators between negative affect, functional disability and emotional distress in patients with fibromyalgia
Clin Exp Rheumatol. 2021 Nov 18. Online ahead of print.ABSTRACTOBJECTIVES: Fibromyalgia (FM) is a prevalent disabling condition characterised by chronic widespread pain. It is considered a complex illness in which the prognosis is conditioned by affective and cognitive mediators still largely unknown in FM. To investigate the correlation between psychological variables (acceptance, negative affect, and mindfulness) and functional disability or physical impact, anxiety/depression symptoms and emotional distress, and also to evaluate the mediating role of acceptance and mindfulness between negative affect, physical impact, a...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Sara Maurel Naia S áez-Francàs Natalia Calvo Jos é Alegre-Martín Jes ús Castro-Marrero Source Type: research

Blood chemokine levels are markers of disease activity but not predictors of remission in early rheumatoid arthritis
CONCLUSIONS: In patients with untreated eRA, plasma levels of several chemokines correlate with disease activity at baseline but cannot predict remission after 24 weeks of treatment with methotrexate combined with prednisolone, anti‑TNF, CTLA‑4Ig or anti‑IL6R.PMID:34796837 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Jonathan Aldridge Anna-Carin Lundell Kerstin Andersson Linda Mark Merete Lund Hetland Mikkel Østergaard Till Uhlig Marte Schrumpf Heiberg Espen A Haavardsholm Michael Nurmohamed Jon Lampa Dan Nordstr öm Kim H ørslev-Petersen Bjorn Gudbjornsson Gerdur G Source Type: research

Idiopathic retroperitoneal fibrosis: clinical features, treatment modalities, relapse rate in Greek patients and a review of the literature
CONCLUSIONS: Relapse occurred in one-fifth of patients independently of the initial clinical/radiographic presentation or treatment used. iRPF patients with baseline elevated serum IgG4 levels have a higher relapse rate.PMID:34796838 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Evangelia Zampeli Aliki I Venetsanopoulou Sophia Christaki Ourania D Argyropoulou Kyriaki A Boki Menelaos N Manoussakis Foteini N Skopouli Athanasios G Tzioufas Haralampos M Moutsopoulos Source Type: research

Prediction of the intolerance or non-responder to Janus kinase inhibitors in patients with rheumatoid arthritis: a preliminary retrospective study with integrative cluster analysis
CONCLUSIONS: A subpopulation of RA patients with a combination of the following three components, seronegativity, advanced joint destruction and absence of RA-ILD, was identified as being prone to JAKis-IR.PMID:34796839 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Masanari Sugawara Yuichiro Fujieda Atsushi Noguchi Shun Tanimura Yuka Shimizu Ikuma Nakagawa Masaru Yoshimura Nobuya Abe Michihito Kono Masaru Kato Kenji Oku Olga Amengual Isao Yokota Hiroki Takahashi Tatsuya Atsumi Source Type: research

Outcomes after lung transplantation among Chinese patients with connective tissue disease-associated interstitial lung disease and pulmonary hypertension: a retrospective cohort study
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.ABSTRACTOBJECTIVES: The present study aimed to compare the post-lung transplant survival and complications of connective tissue disease (CTD)-related interstitial lung disease (ILD) and/or pulmonary arterial hypertension with idiopathic pulmonary fibrosis (IPF).METHODS: The clinical data of patients with CTD-ILD or IPF who received lung transplantation between 2015 and 2020 were retrospectively reviewed. Cumulative survival rates after transplantation were estimated using the Kaplan-Meier method.RESULTS: The study included 31 patients with confirmed CTD-ILD and 98 with ...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Chunrong Ju Qiaoyan Lian Ao Chen Xin Xu Jianheng Zhang Qun Luo Danxia Huang Rongchang Chen Jianxing He Source Type: research

Flexion contracture is associated with knee joint degeneration on magnetic resonance imaging: data from the Osteoarthritis Initiative
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.ABSTRACTOBJECTIVES: Knee osteoarthritis (OA) is often accompanied by a flexion contracture (FC), resulting in worse clinical outcomes. Our objective was to determine associations between knee FC and specific regional and/or structural alterations on magnetic resonance imaging (MRI) using the Osteoarthritis Initiative (OAI).METHODS: 600 knees from the Foundation for the National Institutes of Health sub-study of the OAI were included. Knee extension was measured with a goniometer and FC was defined as inability to extend the knee to 0°. Structural alterations within ...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Mark T Campbell Guy Trudel Philip G Conaghan Katherine Reilly Robert J Feibel Dennis McGonagle Source Type: research

Incidence and risk factors of COVID-19 in patients with vasculitis in the first year of the pandemic: a Danish nationwide cohort study
Clin Exp Rheumatol. 2021 Oct 28. Online ahead of print.NO ABSTRACTPMID:34796842 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Salome Kristensen Ren é Cordtz Kirsten Duch Jesper Lindhardsen Christian Torp-Pedersen Lene Dreyer Source Type: research

Intra-articular osteoid osteoma mimicking juvenile psoriatic dactylitis
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796843 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Luciana Breda Giulia Sassano Saverio La Bella Cristina Gentile Lorenzo Sansone Francesco Chiarelli Source Type: research

Clinical implications of fever at diagnosis in polymyalgia rheumatica: an age- and sex-matched case control study of 120 patients. Reply to Milchert et al. and Manzo et al
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796844 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Albrecht Betrains Lennert Boeckxstaens Koen Van Laere Steven Vanderschueren Daniel Blockmans Source Type: research

Work productivity and activity impairment in patients with primary Sj ögren's syndrome
CONCLUSIONS: We found a compromise in all WPAI domains. Arthritis, xerostomia and depression were associated significantly and independently with ADL impairment. Deterioration in ADL was greater in patients treated in public centres. Considering these aspects will allow a better understanding of patients who suffer from this disease.PMID:34796845 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Marisel Vanesa Bejarano Felix Romanini Antonio Catal án Pellet Marta N Mamani Silvia Papasidero Julia Demarchi Cecilia A Asnal C E Crow Alejandro Nitsche L Encinas F Caeiro Carla A Gobbi Eduardo Albiero Andrea G ómez R Águila Maldonado Mercedes Garc í Source Type: research

Fever at diagnosis as a confounding factor in patients with polymyalgia rheumatica. Messages from primary care. Comments on Betrains et al
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796846 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Ciro Manzo Maria Natale Source Type: research

Clinical heterogeneities and prognoses of patients with myositis specific antibody negative dermatomyositis: a retrospective study in China
CONCLUSIONS: Through cluster analysis, different clinical phenotypes of MSA negative DM patients were determined. The prognoses of the two subgroups were different in terms of survival rate and cause of death.PMID:34796847 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Shanshan Li Suhao Gao Qingning Chen Junfeng Han Ling Zhang Yongpeng Ge Yu Zuo Jianghui Duan Xin Lu Guochun Wang Source Type: research

Is there a potential for therapeutic drug monitoring of subcutaneously administered tocilizumab in patients with rheumatoid arthritis in daily practice?
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.NO ABSTRACTPMID:34796848 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Zohra Layegh Femke Hooijberg Carla Bastida Alwin D R Huitema Theo Rispens Gertjan Wolbink Source Type: research

Implications of fever on erythrocyte sedimentation rate but not on C-reactive protein concentrations at the time of diagnosis of polymyalgia rheumatica. Comments on Betrains et al
Clin Exp Rheumatol. 2021 Nov 11. Online ahead of print.NO ABSTRACTPMID:34796849 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Marcin Milchert Alberto Castagna Ciro Manzo Marek Brzosko Source Type: research

Dipeptidyl peptidase 4/CD26 expression in human idiopathic inflammatory myopathies reveals skeletal muscle injury and vascular inflammation
Clin Exp Rheumatol. 2021 Nov 3. Online ahead of print.ABSTRACTOBJECTIVES: We performed a retrospective and prospective observational study to investigate whether the T lymphocyte activation antigen dipeptidyl peptidase 4 (DPP4)/CD26 is expressed in the skeletal muscle of patients with idiopathic inflammatory myopathies (IIM) and whether its expression offers clues to understand the events taking place in the tissue.METHODS: CD26 expression in the muscle, evaluated by immunofluorescence, was assessed in 32 patients with IIM and 5 healthy controls and compared among patients with dermatomyositis (DM), immune-mediated necroti...
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Rebecca De Lorenzo Antonella Monno Clara Sciorati Isabella Lorenzetti Silvia Cavalli Francesco Bonomi Stefano Carlo Previtali Patrizia Rovere-Querini Source Type: research

Development and performance of the Clinical Trials ESSDAI (ClinTrialsESSDAI), consisting of frequently active clinical domains, in two randomised controlled trials in primary Sj ögren's syndrome
CONCLUSIONS: The ClinTrialsESSDAI, consisting of six frequently active clinical domains of the ESSDAI, shows closely similar responsiveness and discrimination between treatment groups compared to the ClinESSDAI and ESSDAI. Therefore, this ClinTrialsESSDAI is not preferable to ClinESSDAI and ESSDAI for use as primary endpoint. A composite endpoint combining response at multiple clinically relevant items seems more suitable as primary study endpoint in pSS.PMID:34796851 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Liseth de Wolff Suzanne Arends Elena Pontarini Michele Bombardieri Simon J Bowman Hendrika Bootsma Source Type: research

Treatment of refractory hypocomplementaemic urticarial vasculitis syndrome progressing to systemic lupus erythematosus with belimumab
Clin Exp Rheumatol. 2021 Nov 17. Online ahead of print.NO ABSTRACTPMID:34796852 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Larissa Valor-M éndez Georg Schett Bernhard Manger Source Type: research

The negative impact of undiagnosed depression in axial spondyloarthropathy
Clin Exp Rheumatol. 2021 Oct 21. Online ahead of print.NO ABSTRACTPMID:34796853 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - November 19, 2021 Category: Rheumatology Authors: Sinead Maguire Phil Gallagher Finbar O'Shea Source Type: research