One year in review 2021: systemic lupus erythematosus
Clin Exp Rheumatol. 2021 Mar-Apr;39(2):231-241. Epub 2021 Apr 9.ABSTRACTIn 2020 many contributions have been produced on SLE. Our critical digest of the recent literature will be focused on genetic factors that contribute to the development of the disease, novel potential therapeutic targets (including IL-23, IL-17, interferons and JAKs), diagnostic and prognostic biomarkers, classification criteria, clinical manifestations and comorbidities. We will then present new treatment options (with a special focus on belimumab, anifrolumab, tacrolimus, voclosporin and EULAR/ERA-EDTA recommendations for the management of LN) and tr...
Source: Clinical and Experimental Rheumatology - April 12, 2021 Category: Rheumatology Authors: Francesca Trentin Dina Zucchi Viola Signorini Elena Elefante Alessandra Bortoluzzi Chiara Tani Source Type: research

High incidence of giant cell arteritis during the COVID-19 pandemic: no causal relationship but possible involvement of stress
Clin Exp Rheumatol. 2021 Apr 1. Online ahead of print.NO ABSTRACTPMID:33822699 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Simon Parreau Eric Liozon Kim-Heang Ly Anne-Laure Fauchais S ébastien Hantz Source Type: research

Consumer perspective on healthcare services for juvenile idiopathic arthritis: results of a multicentre JIA inception cohort study
CONCLUSIONS: According to parents' experience and satisfaction with their child's care, performance at the system level can be further improved by diagnosing JIA earlier, providing additional information at disease onset, and ensuring that the child's social environment is taken into account.PMID:33822700 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Michaela Heinrich-Rohr Kirsten M önkemöller Martina Niewerth Claudia Sengler Ina Liedmann Tilmann Kallinich Gerd Horneff Daniel Windschall Johannes-Peter Haas Frank Dressler Ivan Foeldvari Frank Weller-Heinemann Toni Hospach Jasmin Kuemmerle-Deschner Di Source Type: research

The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features
CONCLUSIONS: Pirfenidone (600-1,800 mg/day) might help improve FVC, with an acceptable safety and tolerability profile in IPAF patients.PMID:33822701 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Tao Chen Qiu-Hong Li Yuan Zhang Cheng-Sheng Yin Dong Weng Ying Zhou Yang Hu Jing-Yun Shi Ya-Nan Chen Shuang Ye Xiao-Dong Wang Chun-Yan Wu Yan Huang Ai-Hong Zhang Hui-Ping Li Source Type: research

Unilateral generalised morphea successfully treated with rituximab and mycophenolate mofetil
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822702 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Lavinia Quintarelli Roberto Maglie Alberto Corr à Margherita Vannucchi Francesca Li Gobbi Marzia Caproni Source Type: research

Seasonal onset of polymyalgia rheumatica: correlations with the pattern of clinical presentation, disease severity and outcome in 383 patients from a single centre
CONCLUSIONS: PMR showed no seasonality of onset, except for the subset associated with TA. A risk factor with seasonal variation is suggested for the pathogenesis of this form of PMR.PMID:33822703 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Alessia Sobrero Sabrina Paolino Elvis Hysa Dario Camellino Veronica Tomatis Maurizio Cutolo Marco Amedeo Cimmino Source Type: research

Relative increase of Th17 phenotype in senescent CD4+CD28null T cells from peripheral blood of patients with rheumatoid arthritis
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822704 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Mariana Patl án Araceli P áez Felipe Mass ó Luis M Amezcua-Guerra Source Type: research

Predictors of renal flares and long-term renal outcome in patients with lupus nephritis: results from daily clinical practice
CONCLUSIONS: Almost one-third of LN patients experience at least one renal relapse during long-term follow up, but only 3% need chronic renal replacement therapy. Our data suggests that early serological remission is associated with a low risk of renal relapse. Decreased renal function at onset and the first year after diagnosis is predictive for decreased renal function at a later stage.PMID:33822705 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Gijs Ligtenberg Suzanne Arends Coen A Stegeman Karina de Leeuw Source Type: research

Do patients with rheumatoid arthritis show a different course of COVID-19 compared to patients with spondyloarthritis?
CONCLUSIONS: The study revealed that the hospitalisation rate during COVID-19 infection, but not the mortality, was significantly higher in RA as compared to SpA patients. This could be explained either by different treatment strategies or by different susceptibilities of the two diseases.PMID:33822706 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Rebecca Hasseli Alexander Pfeil Bimba F Hoyer Andreas Krause Hanns-Martin Lorenz Jutta G Richter Tim Schmeiser Reinhard E Voll Hendrik Schulze-Koops Christof Specker Ulf M üller-Ladner Source Type: research

Counselling patients for return to work on immunosuppression: practices of Canadian specialists during the COVID-19 pandemic
CONCLUSIONS: Almost all rheumatologists, dermatologists and gastroenterologists have been asked to counsel patients on returning to work during the COVID-19 pandemic. Most do not feel informed enough to do so. Medical notes for accommodations are only provided a minority of the time, unless specific factors (e.g. glucocorticoids) are present. Guidance is needed to inform these decisions.PMID:33822707 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Karim Ladak Kevin Winthrop John K Marshall Joel Gelfand Janet Pope Source Type: research

Autologous lipotransfer can improve the outcomes of localised scleroderma
Clin Exp Rheumatol. 2021 Mar 26. Online ahead of print.NO ABSTRACTPMID:33822708 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Benjamin Langridge Faith H K Jeon Aurora Almadori Michelle F Griffin Christopher P Denton Peter E M Butler Source Type: research

Rheumatoid arthritis autoantibodies and their association with age and sex
CONCLUSIONS: Anti-CCP associate with low, and IgA RF with high age at RA onset. RFs and anti-CCP2 display opposing association with sex. These results underscore that studies on RA phenotypes in relation to autoantibodies should accommodate age and sex.PMID:33822709 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Eleftheria Pertsinidou Vivek Anand Manivel Helga Westerlind Lars Klareskog Lars Alfredsson Linda Mathsson-Alm Monika Hansson Saedis Saevarsdottir Johan Askling Johan R önnelid Source Type: research

Factors associated with delayed diagnosis of Sj ögren's syndrome among members of the Japanese Sjögren's Association for Patients
Clin Exp Rheumatol. 2021 Mar 29. Online ahead of print.ABSTRACTOBJECTIVES: The heterogeneous nature of the signs and symptoms of Sjögren's syndrome (SS) often causes delays in diagnosis. The reasons for these delays have not been investigated in Japan and need to be determined.METHODS: We conducted a questionnaire survey of members of the Japanese Sjögren's Association for Patients (JSAP). Questionnaire items were demographic (sex, age at diagnosis and current age) and factors associated with delayed diagnosis (age at first visit to hospital or clinic, medical department first attended, and initial symptoms). Pat...
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Kaori Komori Masahiro Komori Taro Horino Susumu Nishiyama Masami Takei Narufumi Suganuma Source Type: research

Clinical and FDG-PET/CT correlates in patients with polymyalgia rheumatica
CONCLUSIONS: Patients with PMR show a typical joint pattern at FDG-PET. There are no clinical or laboratory predictors of LVV. Imaging appears to be the only tool to assess LVV in these patients.PMID:33822711 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Dario Camellino Francesco Paparo Silvia D Morbelli Giampaola Pesce Matteo Bauckneht Marcello Bagnasco Maurizio Cutolo Gianmario Sambuceti Marco Amedeo Cimmino Source Type: research

High incidence of giant cell arteritis during the COVID-19 pandemic: no causal relationship but possible involvement of stress
Clin Exp Rheumatol. 2021 Apr 1. Online ahead of print.NO ABSTRACTPMID:33822699 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Simon Parreau Eric Liozon Kim-Heang Ly Anne-Laure Fauchais S ébastien Hantz Source Type: research

Consumer perspective on healthcare services for juvenile idiopathic arthritis: results of a multicentre JIA inception cohort study
CONCLUSIONS: According to parents' experience and satisfaction with their child's care, performance at the system level can be further improved by diagnosing JIA earlier, providing additional information at disease onset, and ensuring that the child's social environment is taken into account.PMID:33822700 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Michaela Heinrich-Rohr Kirsten M önkemöller Martina Niewerth Claudia Sengler Ina Liedmann Tilmann Kallinich Gerd Horneff Daniel Windschall Johannes-Peter Haas Frank Dressler Ivan Foeldvari Frank Weller-Heinemann Toni Hospach Jasmin Kuemmerle-Deschner Di Source Type: research

The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features
CONCLUSIONS: Pirfenidone (600-1,800 mg/day) might help improve FVC, with an acceptable safety and tolerability profile in IPAF patients.PMID:33822701 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Tao Chen Qiu-Hong Li Yuan Zhang Cheng-Sheng Yin Dong Weng Ying Zhou Yang Hu Jing-Yun Shi Ya-Nan Chen Shuang Ye Xiao-Dong Wang Chun-Yan Wu Yan Huang Ai-Hong Zhang Hui-Ping Li Source Type: research

Unilateral generalised morphea successfully treated with rituximab and mycophenolate mofetil
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822702 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Lavinia Quintarelli Roberto Maglie Alberto Corr à Margherita Vannucchi Francesca Li Gobbi Marzia Caproni Source Type: research

Seasonal onset of polymyalgia rheumatica: correlations with the pattern of clinical presentation, disease severity and outcome in 383 patients from a single centre
CONCLUSIONS: PMR showed no seasonality of onset, except for the subset associated with TA. A risk factor with seasonal variation is suggested for the pathogenesis of this form of PMR.PMID:33822703 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Alessia Sobrero Sabrina Paolino Elvis Hysa Dario Camellino Veronica Tomatis Maurizio Cutolo Marco Amedeo Cimmino Source Type: research

Relative increase of Th17 phenotype in senescent CD4+CD28null T cells from peripheral blood of patients with rheumatoid arthritis
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822704 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Mariana Patl án Araceli P áez Felipe Mass ó Luis M Amezcua-Guerra Source Type: research

Predictors of renal flares and long-term renal outcome in patients with lupus nephritis: results from daily clinical practice
CONCLUSIONS: Almost one-third of LN patients experience at least one renal relapse during long-term follow up, but only 3% need chronic renal replacement therapy. Our data suggests that early serological remission is associated with a low risk of renal relapse. Decreased renal function at onset and the first year after diagnosis is predictive for decreased renal function at a later stage.PMID:33822705 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Gijs Ligtenberg Suzanne Arends Coen A Stegeman Karina de Leeuw Source Type: research

Do patients with rheumatoid arthritis show a different course of COVID-19 compared to patients with spondyloarthritis?
CONCLUSIONS: The study revealed that the hospitalisation rate during COVID-19 infection, but not the mortality, was significantly higher in RA as compared to SpA patients. This could be explained either by different treatment strategies or by different susceptibilities of the two diseases.PMID:33822706 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Rebecca Hasseli Alexander Pfeil Bimba F Hoyer Andreas Krause Hanns-Martin Lorenz Jutta G Richter Tim Schmeiser Reinhard E Voll Hendrik Schulze-Koops Christof Specker Ulf M üller-Ladner Source Type: research

Counselling patients for return to work on immunosuppression: practices of Canadian specialists during the COVID-19 pandemic
CONCLUSIONS: Almost all rheumatologists, dermatologists and gastroenterologists have been asked to counsel patients on returning to work during the COVID-19 pandemic. Most do not feel informed enough to do so. Medical notes for accommodations are only provided a minority of the time, unless specific factors (e.g. glucocorticoids) are present. Guidance is needed to inform these decisions.PMID:33822707 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Karim Ladak Kevin Winthrop John K Marshall Joel Gelfand Janet Pope Source Type: research

Autologous lipotransfer can improve the outcomes of localised scleroderma
Clin Exp Rheumatol. 2021 Mar 26. Online ahead of print.NO ABSTRACTPMID:33822708 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Benjamin Langridge Faith H K Jeon Aurora Almadori Michelle F Griffin Christopher P Denton Peter E M Butler Source Type: research

Rheumatoid arthritis autoantibodies and their association with age and sex
CONCLUSIONS: Anti-CCP associate with low, and IgA RF with high age at RA onset. RFs and anti-CCP2 display opposing association with sex. These results underscore that studies on RA phenotypes in relation to autoantibodies should accommodate age and sex.PMID:33822709 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Eleftheria Pertsinidou Vivek Anand Manivel Helga Westerlind Lars Klareskog Lars Alfredsson Linda Mathsson-Alm Monika Hansson Saedis Saevarsdottir Johan Askling Johan R önnelid Source Type: research

Factors associated with delayed diagnosis of Sj ögren's syndrome among members of the Japanese Sjögren's Association for Patients
Clin Exp Rheumatol. 2021 Mar 29. Online ahead of print.ABSTRACTOBJECTIVES: The heterogeneous nature of the signs and symptoms of Sjögren's syndrome (SS) often causes delays in diagnosis. The reasons for these delays have not been investigated in Japan and need to be determined.METHODS: We conducted a questionnaire survey of members of the Japanese Sjögren's Association for Patients (JSAP). Questionnaire items were demographic (sex, age at diagnosis and current age) and factors associated with delayed diagnosis (age at first visit to hospital or clinic, medical department first attended, and initial symptoms). Pat...
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Kaori Komori Masahiro Komori Taro Horino Susumu Nishiyama Masami Takei Narufumi Suganuma Source Type: research

Clinical and FDG-PET/CT correlates in patients with polymyalgia rheumatica
CONCLUSIONS: Patients with PMR show a typical joint pattern at FDG-PET. There are no clinical or laboratory predictors of LVV. Imaging appears to be the only tool to assess LVV in these patients.PMID:33822711 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Dario Camellino Francesco Paparo Silvia D Morbelli Giampaola Pesce Matteo Bauckneht Marcello Bagnasco Maurizio Cutolo Gianmario Sambuceti Marco Amedeo Cimmino Source Type: research

High incidence of giant cell arteritis during the COVID-19 pandemic: no causal relationship but possible involvement of stress
Clin Exp Rheumatol. 2021 Apr 1. Online ahead of print.NO ABSTRACTPMID:33822699 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Simon Parreau Eric Liozon Kim-Heang Ly Anne-Laure Fauchais S ébastien Hantz Source Type: research

Consumer perspective on healthcare services for juvenile idiopathic arthritis: results of a multicentre JIA inception cohort study
CONCLUSIONS: According to parents' experience and satisfaction with their child's care, performance at the system level can be further improved by diagnosing JIA earlier, providing additional information at disease onset, and ensuring that the child's social environment is taken into account.PMID:33822700 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Michaela Heinrich-Rohr Kirsten M önkemöller Martina Niewerth Claudia Sengler Ina Liedmann Tilmann Kallinich Gerd Horneff Daniel Windschall Johannes-Peter Haas Frank Dressler Ivan Foeldvari Frank Weller-Heinemann Toni Hospach Jasmin Kuemmerle-Deschner Di Source Type: research

The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features
CONCLUSIONS: Pirfenidone (600-1,800 mg/day) might help improve FVC, with an acceptable safety and tolerability profile in IPAF patients.PMID:33822701 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Tao Chen Qiu-Hong Li Yuan Zhang Cheng-Sheng Yin Dong Weng Ying Zhou Yang Hu Jing-Yun Shi Ya-Nan Chen Shuang Ye Xiao-Dong Wang Chun-Yan Wu Yan Huang Ai-Hong Zhang Hui-Ping Li Source Type: research

Unilateral generalised morphea successfully treated with rituximab and mycophenolate mofetil
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822702 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Lavinia Quintarelli Roberto Maglie Alberto Corr à Margherita Vannucchi Francesca Li Gobbi Marzia Caproni Source Type: research

Seasonal onset of polymyalgia rheumatica: correlations with the pattern of clinical presentation, disease severity and outcome in 383 patients from a single centre
CONCLUSIONS: PMR showed no seasonality of onset, except for the subset associated with TA. A risk factor with seasonal variation is suggested for the pathogenesis of this form of PMR.PMID:33822703 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Alessia Sobrero Sabrina Paolino Elvis Hysa Dario Camellino Veronica Tomatis Maurizio Cutolo Marco Amedeo Cimmino Source Type: research

Relative increase of Th17 phenotype in senescent CD4+CD28null T cells from peripheral blood of patients with rheumatoid arthritis
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822704 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Mariana Patl án Araceli P áez Felipe Mass ó Luis M Amezcua-Guerra Source Type: research

Predictors of renal flares and long-term renal outcome in patients with lupus nephritis: results from daily clinical practice
CONCLUSIONS: Almost one-third of LN patients experience at least one renal relapse during long-term follow up, but only 3% need chronic renal replacement therapy. Our data suggests that early serological remission is associated with a low risk of renal relapse. Decreased renal function at onset and the first year after diagnosis is predictive for decreased renal function at a later stage.PMID:33822705 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Gijs Ligtenberg Suzanne Arends Coen A Stegeman Karina de Leeuw Source Type: research

Do patients with rheumatoid arthritis show a different course of COVID-19 compared to patients with spondyloarthritis?
CONCLUSIONS: The study revealed that the hospitalisation rate during COVID-19 infection, but not the mortality, was significantly higher in RA as compared to SpA patients. This could be explained either by different treatment strategies or by different susceptibilities of the two diseases.PMID:33822706 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Rebecca Hasseli Alexander Pfeil Bimba F Hoyer Andreas Krause Hanns-Martin Lorenz Jutta G Richter Tim Schmeiser Reinhard E Voll Hendrik Schulze-Koops Christof Specker Ulf M üller-Ladner Source Type: research

Counselling patients for return to work on immunosuppression: practices of Canadian specialists during the COVID-19 pandemic
CONCLUSIONS: Almost all rheumatologists, dermatologists and gastroenterologists have been asked to counsel patients on returning to work during the COVID-19 pandemic. Most do not feel informed enough to do so. Medical notes for accommodations are only provided a minority of the time, unless specific factors (e.g. glucocorticoids) are present. Guidance is needed to inform these decisions.PMID:33822707 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Karim Ladak Kevin Winthrop John K Marshall Joel Gelfand Janet Pope Source Type: research

Autologous lipotransfer can improve the outcomes of localised scleroderma
Clin Exp Rheumatol. 2021 Mar 26. Online ahead of print.NO ABSTRACTPMID:33822708 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Benjamin Langridge Faith H K Jeon Aurora Almadori Michelle F Griffin Christopher P Denton Peter E M Butler Source Type: research

Rheumatoid arthritis autoantibodies and their association with age and sex
CONCLUSIONS: Anti-CCP associate with low, and IgA RF with high age at RA onset. RFs and anti-CCP2 display opposing association with sex. These results underscore that studies on RA phenotypes in relation to autoantibodies should accommodate age and sex.PMID:33822709 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Eleftheria Pertsinidou Vivek Anand Manivel Helga Westerlind Lars Klareskog Lars Alfredsson Linda Mathsson-Alm Monika Hansson Saedis Saevarsdottir Johan Askling Johan R önnelid Source Type: research

Factors associated with delayed diagnosis of Sj ögren's syndrome among members of the Japanese Sjögren's Association for Patients
Clin Exp Rheumatol. 2021 Mar 29. Online ahead of print.ABSTRACTOBJECTIVES: The heterogeneous nature of the signs and symptoms of Sjögren's syndrome (SS) often causes delays in diagnosis. The reasons for these delays have not been investigated in Japan and need to be determined.METHODS: We conducted a questionnaire survey of members of the Japanese Sjögren's Association for Patients (JSAP). Questionnaire items were demographic (sex, age at diagnosis and current age) and factors associated with delayed diagnosis (age at first visit to hospital or clinic, medical department first attended, and initial symptoms). Pat...
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Kaori Komori Masahiro Komori Taro Horino Susumu Nishiyama Masami Takei Narufumi Suganuma Source Type: research

Clinical and FDG-PET/CT correlates in patients with polymyalgia rheumatica
CONCLUSIONS: Patients with PMR show a typical joint pattern at FDG-PET. There are no clinical or laboratory predictors of LVV. Imaging appears to be the only tool to assess LVV in these patients.PMID:33822711 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Dario Camellino Francesco Paparo Silvia D Morbelli Giampaola Pesce Matteo Bauckneht Marcello Bagnasco Maurizio Cutolo Gianmario Sambuceti Marco Amedeo Cimmino Source Type: research

High incidence of giant cell arteritis during the COVID-19 pandemic: no causal relationship but possible involvement of stress
Clin Exp Rheumatol. 2021 Apr 1. Online ahead of print.NO ABSTRACTPMID:33822699 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Simon Parreau Eric Liozon Kim-Heang Ly Anne-Laure Fauchais S ébastien Hantz Source Type: research

Consumer perspective on healthcare services for juvenile idiopathic arthritis: results of a multicentre JIA inception cohort study
CONCLUSIONS: According to parents' experience and satisfaction with their child's care, performance at the system level can be further improved by diagnosing JIA earlier, providing additional information at disease onset, and ensuring that the child's social environment is taken into account.PMID:33822700 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Michaela Heinrich-Rohr Kirsten M önkemöller Martina Niewerth Claudia Sengler Ina Liedmann Tilmann Kallinich Gerd Horneff Daniel Windschall Johannes-Peter Haas Frank Dressler Ivan Foeldvari Frank Weller-Heinemann Toni Hospach Jasmin Kuemmerle-Deschner Di Source Type: research

The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features
CONCLUSIONS: Pirfenidone (600-1,800 mg/day) might help improve FVC, with an acceptable safety and tolerability profile in IPAF patients.PMID:33822701 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Tao Chen Qiu-Hong Li Yuan Zhang Cheng-Sheng Yin Dong Weng Ying Zhou Yang Hu Jing-Yun Shi Ya-Nan Chen Shuang Ye Xiao-Dong Wang Chun-Yan Wu Yan Huang Ai-Hong Zhang Hui-Ping Li Source Type: research

Unilateral generalised morphea successfully treated with rituximab and mycophenolate mofetil
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822702 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Lavinia Quintarelli Roberto Maglie Alberto Corr à Margherita Vannucchi Francesca Li Gobbi Marzia Caproni Source Type: research

Seasonal onset of polymyalgia rheumatica: correlations with the pattern of clinical presentation, disease severity and outcome in 383 patients from a single centre
CONCLUSIONS: PMR showed no seasonality of onset, except for the subset associated with TA. A risk factor with seasonal variation is suggested for the pathogenesis of this form of PMR.PMID:33822703 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Alessia Sobrero Sabrina Paolino Elvis Hysa Dario Camellino Veronica Tomatis Maurizio Cutolo Marco Amedeo Cimmino Source Type: research

Relative increase of Th17 phenotype in senescent CD4+CD28null T cells from peripheral blood of patients with rheumatoid arthritis
Clin Exp Rheumatol. 2021 Mar 30. Online ahead of print.NO ABSTRACTPMID:33822704 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Mariana Patl án Araceli P áez Felipe Mass ó Luis M Amezcua-Guerra Source Type: research

Predictors of renal flares and long-term renal outcome in patients with lupus nephritis: results from daily clinical practice
CONCLUSIONS: Almost one-third of LN patients experience at least one renal relapse during long-term follow up, but only 3% need chronic renal replacement therapy. Our data suggests that early serological remission is associated with a low risk of renal relapse. Decreased renal function at onset and the first year after diagnosis is predictive for decreased renal function at a later stage.PMID:33822705 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Gijs Ligtenberg Suzanne Arends Coen A Stegeman Karina de Leeuw Source Type: research

Do patients with rheumatoid arthritis show a different course of COVID-19 compared to patients with spondyloarthritis?
CONCLUSIONS: The study revealed that the hospitalisation rate during COVID-19 infection, but not the mortality, was significantly higher in RA as compared to SpA patients. This could be explained either by different treatment strategies or by different susceptibilities of the two diseases.PMID:33822706 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - April 6, 2021 Category: Rheumatology Authors: Rebecca Hasseli Alexander Pfeil Bimba F Hoyer Andreas Krause Hanns-Martin Lorenz Jutta G Richter Tim Schmeiser Reinhard E Voll Hendrik Schulze-Koops Christof Specker Ulf M üller-Ladner Source Type: research