Clinical and Experimental Rheumatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Association between treatment type and therapeutic response according to clinical form of SAPHO syndrome in adults from a multicentre retrospective cohort study
Clin Exp Rheumatol. 2024 Mar 19. doi: 10.55563/clinexprheumatol/n837l6. Online ahead of print.NO ABSTRACTPMID:38525997 | DOI:10.55563/clinexprheumatol/n837l6 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Pauline Brevet Paul Michelin Christian Marcelli Didier Alcaix Thierry Lequerre Olivier Vittecoq Source Type: research

Elevated DAS28-ESR in patients with rheumatoid arthritis who have comorbid fibromyalgia is associated more with tender joint counts than with patient global assessment or swollen joint counts: implications for assessment of inflammatory activity
CONCLUSIONS: DAS28-ESR is elevated significantly in FM+ vs. FM- RA patients; pooled effect sizes were highest for TJC, followed by PATGL, SJC and ESR. The findings appear relevant to response and remission criteria, treat-to-target, and general management of RA.PMID:38525998 | DOI:10.55563/clinexprheumatol/vfvso2 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Sandhya Kannayiram Juan Schmukler Tengfei Li Nicola Goodson Aarthi Sridhar Theodore Pincus Source Type: research

Polyacrylamide gel versus hyaluronic acid for the treatment of knee osteoarthritis: a randomised controlled study
CONCLUSIONS: iPAAG was found to be as effective and safe as HA for treatment of knee OA symptoms for at least 1 year after a single injection.PMID:38525999 | DOI:10.55563/clinexprheumatol/i3fqee (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Henning Bliddal Jannie Beier Andreas Hartkopp Philip G Conaghan Marius Henriksen Source Type: research

Rilonacept use in lupus pericarditis
CONCLUSIONS: Rilonacept successfully treated lupus pericarditis in this case series. Rilonacept should be considered for the treatment of lupus pericarditis.PMID:38526001 | DOI:10.55563/clinexprheumatol/pb3hzb (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Andrea Fava Michael Cammarata Luigi Adamo Source Type: research

A large cohort comparison of very late-onset systemic lupus erythematosus with younger-onset patients
CONCLUSIONS: Compared with younger patients, in vlSLE, female predominance is less pronounced. Arthritis, anti-dsDNA antibodies and low C3 levels are less frequent. SS and RA are more common. Despite lower disease activity, vlSLE patients have the lowest survival rate. While uncommon, SLE should not be excluded as a possible diagnosis in the elderly.PMID:38526004 | DOI:10.55563/clinexprheumatol/jgsyos (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Luisa Viveiros Ana Neves Teresa Gouveia David A Isenberg Source Type: research

The functional disabilities of the dominant and opposite hands in patients with systemic sclerosis
CONCLUSIONS: The dominant hand exhibited significantly more skin sclerosis and mean flexion deterioration, a lower Kapandji score, and a tendency toward reduced mean extension, compared with the other hand. No vascular pathology was noted in either hand. Larger studies are needed to confirm these results and to draw therapeutic conclusions.PMID:38526006 | DOI:10.55563/clinexprheumatol/db7upl (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Salom é Fourmond Simon Parreau St éphanie Dumonteil Charlotte Verdie-Kessler Kim-Heang Ly Philippe Lacroix Anne-Laure Fauchais Philippe Bernard Sylvain Palat Source Type: research

Giant cell arteritis in patients with systemic sclerosis: a case series
CONCLUSIONS: Herein we present the largest single-institution series of patients with a history of GCA and SSc, an uncommon combination. Glucocorticoid treatment for GCA did not precipitate SRC, even in those with prior history of SRC. Further investigation regarding the benefit of tocilizumab in patients with SSc and GCA is required.PMID:38526007 | DOI:10.55563/clinexprheumatol/pn1o3u (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Max Guarda Alexandria Roy Michelle Burke Kenneth J Warrington Matthew J Koster Source Type: research

Key considerations for modelling the long-term costs and benefits of treatments for ANCA-associated vasculitis
CONCLUSIONS: Economic evaluation of new treatments for AAV needs to capture all relevant downstream effects. ESRD is a key driver of cost-effectiveness but is associated with major uncertainty. Future observational studies need to offer sufficient detail to allow for differentiation in event rates across treatment options.PMID:38526008 | DOI:10.55563/clinexprheumatol/eektem (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Vladislav Berdunov Antonio Ramirez de Arellano Tara Li Helene Vintderdag Garth Baxter Source Type: research

First-year cumulative myeloperoxidase-ANCA titres are associated with all-cause mortality in patients with microscopic polyangiitis
CONCLUSIONS: This is the first study to demonstrate the association between first-year cumulative MPO-ANCA titres and all-cause mortality during follow-up in patients with MPA.PMID:38526013 | DOI:10.55563/clinexprheumatol/jui6xj (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 25, 2024 Category: Rheumatology Authors: Woongchan Rah Jason Jungsik Song Yong-Beom Park Sang-Won Lee Source Type: research

Clinical, histologic and prognostic features of clinically amyopathic dermatomyositis
CONCLUSIONS: CADM patients differ in disease onset, autoantibody profiles, joint and lung involvement. While laboratory and instrumental tests have not shown muscle involvement in CADM, many muscle biopsies have shown MHC-I overexpression.PMID:38488091 | DOI:10.55563/clinexprheumatol/kgpnbq (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Marco Fornaro Francesco Girolamo Margherita Giannini Laura Coladonato Adriana Capuano Marco Capodiferro Dario D'Abbicco Maddalena Ruggieri Mariangela Mastrapasqua Florenzo Iannone Source Type: research

Nailfold capillaroscopy findings of a multicentric multi-ethnic cohort of patients with idiopathic inflammatory myopathies
CONCLUSIONS: NVC abnormalities are related to the diagnosis, clinical features, disease activity, and autoantibodies of patients with IIM.PMID:38488092 | DOI:10.55563/clinexprheumatol/l9gudh (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Jiram Torres-Ruiz Iago Pinal-Fernandez Albert Selva-O'Callaghan Bianca Campbell Sandra Mu ñoz-Braceras Nancy R Mej ía-Domínguez Carlos N úñez-Álvarez Jos é Milisenda Maria Casal-Dom ínguez Katherine Pak Alfredo Guill én-Del-Castillo Ernesto Trall Source Type: research

Mental health in paediatric and adult myositis-related diseases: current state of research, interventions, and future steps from the MIHRA Psychological Impact Scientific Working Group
Clin Exp Rheumatol. 2024 Feb;42(2):413-424. doi: 10.55563/clinexprheumatol/cngdfn. Epub 2024 Mar 14.ABSTRACTPsychological and emotional well-being are critical aspects of overall health for individuals with chronic rheumatologic conditions. Mental health-related literature, however, predominantly focuses on systemic lupus erythematosus or rheumatoid arthritis, with limited emphasis on idiopathic inflammatory myopathies (IIMs). High proportions of those with juvenile myositis report psychological distress at levels warranting mental health referral. Adults with dermatomyositis diagnosed with depression or anxiety do not rec...
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Aviya Lanis Helene Alexanderson Kaveh Ardalan Suzanne Edison Christopher D Graham Ingrid de Groot Latika Gupta Susan Kim Andrea M Knight Linda Kobert Polly Livermore Christian Lood Clarissa Pilkington Malin Regardt Tamar B Rubinstein Susan Shenoi Luke Tur Source Type: research

Agreement between local and central anti-synthetase antibodies detection: results from the Classification Criteria of Anti-Synthetase Syndrome project biobank
CONCLUSIONS: Our study evaluates the performance of real-world identification of anti-synthetase antibodies in a large cohort of multi-national patients with ASSD and controls. Our analysis reinforces the reliability of real-world anti-Jo1 detection methods. In contrast, challenges persist for anti-non-Jo1 identification, particularly anti-PL7 and rarer antibodies such as anti-OJ/KS. Clinicians should exercise caution when interpreting anti-synthetase antibodies, especially when commercial immunoassays test positive for non-anti-Jo1 antibodies.PMID:38488094 | DOI:10.55563/clinexprheumatol/s14zq8 (Source: Clinical and Exper...
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Aravinthan Loganathan Giovanni Zanframundo Akira Yoshida Sara Faghihi-Kashani Iazsmin Bauer Ventura Eduardo Dourado Francisca Bozan Gianluca Sambataro Yasuhiko Yamano Sharon Sangmee Bae Darosa Lim Angela Ceribelli Natasa Isailovic Carlo Selmi Noreen Ferti Source Type: research

Polymyositis is a rare and favourable outcome subtype of idiopathic inflammatory myopathy in Chinese patients
CONCLUSIONS: Strictly defined typical PM is a rare clinical subtype in Chinese IIM patients. Typical PM patients with classical pathology were MSA-negative and responded well to treatment and had a favourable prognosis. It is crucial for clinicians to combine clinical, serological, and pathological features to properly distinguish PM from other IIM subtypes.PMID:38488095 | DOI:10.55563/clinexprheumatol/7v9d2x (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Chao Sun Xiaolan Tian Hongxia Yang Hanbo Yang Shanshan Li Wei Jiang Qinglin Peng Guochun Wang Xin Lu Source Type: research

Subclinical myocardial involvement in a cohort of patients with antisynthetase syndrome
CONCLUSIONS: Subclinical myocardial involvement in ASSD is not rare (32%) although its clinical significance is uncertain. Myocardial oedema (T2) was the most frequent finding, followed by increased T1 and/or ECV values likely signalling interstitial fibrosis. Of note, patients in the acute phase showed elevated T2 values.PMID:38488096 | DOI:10.55563/clinexprheumatol/tgcrtf (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 15, 2024 Category: Rheumatology Authors: Albert Gil-Vila Gemma Burcet-Rodriguez Ernesto Trallero-Aragu ás Hug Cuellar-Calabria Albert Selva-O'Callaghan Source Type: research