Clinical and Experimental Rheumatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Collaborative research in myositis-related disorders: MIHRA, a global shared community model
Clin Exp Rheumatol. 2024 Mar 4. doi: 10.55563/clinexprheumatol/hc1lsf. Online ahead of print.ABSTRACTMyositis International Health and Research Collaborative Alliance (MIHRA) is a newly formed purpose-built non-profit charitable research organization dedicated to accelerating international clinical trial readiness, global professional and lay education, career development and rare disease advocacy in IIM-related disorders. In its long form, the name expresses the community's scope of engagement and intent. In its abbreviation, MIHRA, conveys linguistic roots across many languages, that reflects the IIM community's spirit w...
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Lesley Ann Saketkoo Julie J Paik Helene Alexanderson Mazen M Dimachkie Floranne C Ernste Elie Naddaf Barbara Shafranski Latika Gupta Christopher A Mecoli Didem Saygin Jemima Albayda Pari Basharat Jessica A Day Antonia Valenzuela Rachel Bromley Ingrid de G Source Type: research

Treatment with lysophosphatidic acid improves glomerulonephritis through the suppression of macrophage activation in a murine model of systemic lupus erythematosus
CONCLUSIONS: These results suggest that LPA may improve glomerulonephritis by suppressing macrophage activation in MRL/lpr mice.PMID:38436267 | DOI:10.55563/clinexprheumatol/ov6027 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Wataru Nagata Eiji Takayama Keiichi Nakagawa Akiho Koizumi Yukiko Ohsawa Hiroyasu Goto Aoi Yamashiro Yuki Ishinoda Keiko Tanoue Hiroo Kumagai Naoki Oshima Toshiaki Ishizuka Source Type: research

Prediction of the activity of early ankylosing spondylitis using radiomics texture analysis on STIR
CONCLUSIONS: Radiomics analysis based on STIR texture analysis has a good prediction for the evaluation of bone marrow oedema activity of sacroiliac joints in AS. It can be a new non-invasive and objective evaluation method for AS activity.PMID:38436270 | DOI:10.55563/clinexprheumatol/99pc16 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Zhaojuan Shi Zhe Yang Datian Su Juan Cheng Zhaoxia Shi Mei Wang Hui Zheng Jiankui Han Changqin Li Jian Qin Source Type: research

Performance of the 2017 EULAR/ACR Classification Criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups: a scoping review
Clin Exp Rheumatol. 2024 Feb 28. doi: 10.55563/clinexprheumatol/vuc5py. Online ahead of print.ABSTRACTThe 2017 EULAR/ACR classification criteria for adult/juvenile idiopathic inflammatory myopathies (IIM) were established using a data-driven approach by an international group of myositis experts to allow classification of IIM and its major subtypes. Since their publication, the performance of the criteria has been tested in multiple cohorts worldwide and significant limitations have been identified. Moreover, the understanding and classification of IIM have evolved since 2017. This scoping review was undertaken as part of ...
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Didem Saygin Stefanie Glaubitz Rachel Zeng Matteo Bottai Marianne de Visser Mazen M Dimachkie David Fiorentino Ingrid Gerhardson Masataka Kuwana Frederick W Miller Merrilee Needham Lisa G Rider Yasser Salem Silke Schl üter Samuel K Shinjo Guochun Wang Vi Source Type: research

Increased expression of omentin-1 is associated with synovitis and bone destruction in rheumatoid arthritis
CONCLUSIONS: Our results suggested that omentin-1 was up-regulated in RA and can exacerbate synovitis and joint destruction which may provide new insight into the pathogenesis of RA.PMID:38436296 | DOI:10.55563/clinexprheumatol/7pcgv7 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Yali Wu Xin Li Jing Ke Baoyu Zhang Dong Zhao Source Type: research

IL-17-producing cells in ankylosing spondylitis patients show gender-based differences in gene expression
CONCLUSIONS: Transcriptomic analysis revealed that male AS patients exhibit distinct expression patterns of IL-17 pro-inflammatory genes, which may contribute to the phenotypic differences observed between genders in AS.PMID:38436300 | DOI:10.55563/clinexprheumatol/do7osn (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Chan Mi Lee Ernest Ricky Chan Darerian Schueller Maya Breitman Maricela Haghiac Marina Magrey Source Type: research

Exercise recommendations for patients with myositis: a narrative review of safety and efficacy
Clin Exp Rheumatol. 2024 Feb 20. doi: 10.55563/clinexprheumatol/m8fbs1. Online ahead of print.ABSTRACTIdiopathic inflammatory myopathies (IIM) are marked by progressive muscle weakness and lasting disability. Therapies targeting patient well-being include the use of prescription drugs as well as exercise. Maintaining or increasing muscular strength and endurance as well as cardiorespiratory fitness (CRF) improves quality of life (QoL) as well as functional status in IIM patients. This narrative review highlights exercise interventions in patients of different IIM subtypes with the intent to provide a summary table with exe...
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Nicole Varone Jose Hinojosa Dhruv Nandakumar Naysa Modi Abhiram R Bhashyam Salman F Bhai Source Type: research

Phenotypic spectrum of inclusion body myositis
Clin Exp Rheumatol. 2024 Feb 28. doi: 10.55563/clinexprheumatol/fhrx3q. Online ahead of print.ABSTRACTInclusion body myositis (IBM) is a progressive, debilitating muscle disease commonly encountered in patients over the age of 50. IBM typically presents with asymmetric, painless, progressive weakness and atrophy of deep finger flexors and/or quadriceps muscle. Many patients with IBM develop dysphagia. However, atypical presentations of IBM with isolated dysphagia, asymptomatic hyper-CKemia, foot drop, proximal weakness, axial weakness, and facial diplegia have been reported. Other acquired and some inherited disorders may ...
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Bhaskar Roy Mazen M Dimachkie Elie Naddaf Source Type: research

Two-year treatment persistence with subcutaneous abatacept in rheumatoid arthritis: results from the French cohort of the ASCORE study
CONCLUSIONS: In current practice in France, the rate of subcutaneous abatacept persistence at 2 years was comparable with that of the intravenous form. Treatment persistence was higher when abatacept was used as first-line versus later-line biologic therapy.PMID:38436358 | DOI:10.55563/clinexprheumatol/ddx0fz (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Ren é-Marc Flipo Arnaud Constantin Philippe Goupille M élanie Chartier Ana ël Ohayon Xavier Mariette Source Type: research