Announcement
(Source: European Spine Journal)
Source: European Spine Journal - April 22, 2019 Category: Orthopaedics Source Type: research

Effects of decompressive operation on cardiac autonomic regulation in patients with cervical spondylotic myelopathy: analysis of blood pressure, heart rate, and heart rate variability
ConclusionsCervical decompression operation could improve both somatic neurological function and cardiac autonomic regulation in CSM patients, and achieved JOA score was significantly positively correlated with improvement in HRV and cardiac parasympathetic activity.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 22, 2019 Category: Orthopaedics Source Type: research

Indirect foraminal decompression and improvement in the lumbar alignment after percutaneous cement discoplasty
The objective of this study was to evaluate the effects of PCD on spinopelvic radiological parameters and their associations with the clinical outcome.MethodsRetrospective analysis of prospectively collected dataset of 28 patients (112 lumbar segments) who underwent single- or multilevel PCD was performed. Spinopelvic, intrasegmental and intersegmental parameters were measured on lumbar X-rays pre-, postoperatively and 6  months after the surgery. Correlations between radiological parameters and clinical outcome data were determined.ResultsSacral slope significantly increased (p  
Source: European Spine Journal - April 20, 2019 Category: Orthopaedics Source Type: research

Pedicle screw insertion with patient-specific 3D-printed guides based on low-dose CT scan is more accurate than free-hand technique in spine deformity patients: a prospective, randomized clinical trial
AbstractBackgroundScrew misplacement incidence can be as high as 15 –30% in spine deformity surgery, with possible devastating consequences. Some technical solutions to prevent misplacement require expensive devices. MySpineTM comprises a low-dose CT scan of the patient ’s spine to build a virtual model of the spine to plan the screw trajectories and a 3D-printed patient-specific guide system to prepare the screw trajectories and to implant the screws in the vertebrae in order to increase reproducibility and safety of the implants. The aim of this open-label, sin gle-center, prospective randomized clinical tria...
Source: European Spine Journal - April 20, 2019 Category: Orthopaedics Source Type: research

Development of a standard set of outcome measures for non-specific low back pain in Dutch primary care physiotherapy practices: a Delphi study
ConclusionThis study presents a standard set of outcome measures for patients with NSLBP in primary care physiotherapy accepted for relevance and feasibility by stakeholders. The standard set is currently used in daily practice and tested on validity and reliability in a pilot study.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 19, 2019 Category: Orthopaedics Source Type: research

Restoration of normal pelvic balance from surgical reduction in high-grade spondylolisthesis
AbstractPurposeTo investigate the effectiveness of surgical reduction in high-grade spondylolisthesis in maintaining or restoring a normal pelvic balance, as related to the QoL.MethodsIt is a retrospective analysis of prospectively collected data of 60 patients (17 males, 43 females) aged 15  ± 3.1 years who underwent surgery for high-grade spondylolisthesis and were followed for a minimum of 2 years after surgery. Patients with a residual high-grade slip following surgery were referred to the postoperative high-grade (PHG) group, while patients with a residual low-grade slip wer e referred t...
Source: European Spine Journal - April 15, 2019 Category: Orthopaedics Source Type: research

Modic I changes size increase from supine to standing MRI correlates with increase in pain intensity in standing position: uncovering the “biomechanical stress” and “active discopathy” theories in low back pain
ConclusionsOur results showed the modifications of Modic I changes under loading, with MRI evidence of increased MC area extent in the upright position and correlation between Modic changes extension increase and increase in pain in the standing position. Weight-bearing MRI scans represent a valuable complement to standard sequences since they provide the radiologist with additional diagnostic information about low back pain.Graphical abstract These slides can be retrieved from Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 15, 2019 Category: Orthopaedics Source Type: research

Grammer european spine journal award for basic science and applied research 2017/2018
(Source: European Spine Journal)
Source: European Spine Journal - April 15, 2019 Category: Orthopaedics Source Type: research

European spine journal max aebi award for clinical sciences 2017/2018
(Source: European Spine Journal)
Source: European Spine Journal - April 15, 2019 Category: Orthopaedics Source Type: research

L3 translation predicts when L3 is not distal enough for an “ideal” result in Lenke 5 curves
ConclusionWhile multiple variables are important in achieving an “ideal” outcome in Lenke 5 curves, this study found preoperative L3 translation was the most important predictor of success with an L3 translation
Source: European Spine Journal - April 12, 2019 Category: Orthopaedics Source Type: research

Spontaneous spinal epidural haematomas in children
ConclusionsSSEHs affect all paediatric age groups and typically present with neurological dysfunction and/or back pain. The initial diagnosis is incorrect in up to 28% of cases, but cross-sectional spinal imaging is diagnostic. Most SSEHs are located in the cervico-thoracic region and affect multiple spinal levels. The treatment depends on whether the patient has a bleeding disorder and their neurological status.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 10, 2019 Category: Orthopaedics Source Type: research

En bloc spondylectomy in patients older than 60  years: indications, results and complications in a series of 37 patients
ConclusionsPrimary malignant or locally aggressive bone tumors of the spine should be treated with wide surgery also in the older age, although the complications rate and the risk of patient survival can be considered high.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 10, 2019 Category: Orthopaedics Source Type: research

Are postoperative standing radiographs relevant before hospital discharge in adolescent idiopathic scoliosis?
ConclusionThere is no need for additional immediate postoperative radiographs in AIS, if an intraoperative radiograph has already been taken. This finding could help reducing radiation exposure in immature patients and should be further studied in other etiologies.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 10, 2019 Category: Orthopaedics Source Type: research

Risk factors for postoperative pulmonary complications in the treatment of non-degenerative scoliosis by posterior instrumentation and fusion
AbstractPurposeThe aim of this study was to evaluate the prevalence and risk factors for postoperative pulmonary complications (PPC) after posterior instrumentation and fusion (PIF) in patients with non-degenerative scoliosis.MethodsWe retrospectively evaluated 703 patients (224 males, 479 females) diagnosed with non-degenerative scoliosis who underwent PIF in our center from January 2010 to January 2018. Preoperative, perioperative, demographic data, surgical methods and radiographic parameters were extracted and analyzed to identify risk factors for PPC.ResultsThe mean age of the patients was 20.8  ±&thinsp...
Source: European Spine Journal - April 8, 2019 Category: Orthopaedics Source Type: research

Implementation of augmented reality support in spine surgery
ConclusionsA microscope-based AR environment was successfully implemented for spinal surgery. The application of iCT for registration imaging ensures high navigational accuracy. AR greatly supports the surgeon in understanding the 3-D anatomy thereby facilitating surgery.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 5, 2019 Category: Orthopaedics Source Type: research

Postoperative shoulder imbalance in adolescent idiopathic scoliosis: risk factors and predictive index
ConclusionsTo prevent PSI, we recommend sufficient correction of AVT of PTC and prevention of adding-on.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 4, 2019 Category: Orthopaedics Source Type: research

Predicting discharge placement after elective surgery for lumbar spinal stenosis using machine learning methods
ConclusionsA machine learning algorithm is able to predict discharge placement after surgery for lumbar spinal stenosis with both good discrimination and calibration. Implementing this type of algorithm in clinical practice could avert risks associated with delayed discharge and lower costs.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - April 2, 2019 Category: Orthopaedics Source Type: research

Expert ’s Comment concerning Grand Rounds Case entitled “The natural history of thoracolumbar kyphosis in achondroplasia” by Ahmed M, El-Makhy M, Grevitt M (Eur Spine J; 2016: https://doi.org/10.1007/s00586-016-4861-1)
(Source: European Spine Journal)
Source: European Spine Journal - April 2, 2019 Category: Orthopaedics Source Type: research

Announcements
(Source: European Spine Journal)
Source: European Spine Journal - April 1, 2019 Category: Orthopaedics Source Type: research

Correction to: Efficacy of the Game Ready ® cooling device on postoperative analgesia after scoliosis surgery in children
Unfortunately, one co-author name was incorrectly published in the original publication. The complete correct name of the co-author is given below. (Source: European Spine Journal)
Source: European Spine Journal - March 30, 2019 Category: Orthopaedics Source Type: research

Development of a machine learning algorithm predicting discharge placement after surgery for spondylolisthesis
ConclusionThis study has shown that it is possible to create a predictive machine learning algorithm with both good accuracy and calibration to predict discharge placement. Using our methodology, this type of model can be developed for many other conditions and (elective) treatments.Graphical abstract These slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 27, 2019 Category: Orthopaedics Source Type: research

Criteria for surgical reduction in high-grade lumbosacral spondylolisthesis based on quality of life measures
ConclusionsWhen performing surgery in young patients with high-grade lumbosacral spondylolisthesis, achieving normal pelvic balance is the key because it is associated with improved quality of life. Reduction to a low-grade slip is predictive of improved mental health, but reduction in lumbosacral angle is not associated with postoperative quality of life. There was a tendency for obtaining normal postoperative balance in patients with postoperative L5 incidence 60 ° or smaller.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 26, 2019 Category: Orthopaedics Source Type: research

An evaluation of contrast dispersal pattern on preganglionic epidural injection through trans-lateral recess approach in patients with lumbosacral radiculopathy
ConclusionsWhen delivered using the TLR approach, epidural injections result in excellent drug spread within the preganglionic area (i.e., ventral epidural contrast filling and periradicular infiltration of exiting and transversing nerve roots). As noted previously that higher rates of pre-ganglionic epidural infiltration might be led to improvements in clinical pain and disability, epidural injections delivered using the TLR approach are expected to complement existing epidural modalities.Graphical abstract These slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 25, 2019 Category: Orthopaedics Source Type: research

Early versus delayed decompression for traumatic cervical spinal cord injury: application of the AOSpine subaxial cervical spinal injury classification system to guide surgical timing
AbstractPurposeApplication of AOSpine subaxial cervical spine injury classification system to explore the optimal surgical decompression timing for different types of traumatic cervical spinal cord injury (CSCI).MethodsA single-center prospective cohort study was conducted that included patients with traumatic CSCIs (C3 –C7) between February 2015 and October 2016. After enrollment, patients underwent either early (
Source: European Spine Journal - March 22, 2019 Category: Orthopaedics Source Type: research

Predictive formula of ideal lumbar lordosis and lower lumbar lordosis determined by individual pelvic incidence in asymptomatic elderly population
This study aimed to obtain reference values of lumbar lordosis (LL) and lower LL (LLL) from normal asymptomatic groups, determine the relationship between them and pelvic incidence (PI), and establish the predictive formula for ideal LLL in the elderly Korean population.MethodsStanding plain lateral radiographs of the whole spine, including the pelvis, were analyzed in asymptomatic adult male volunteers without back pain or prior surgery involving the spine or lower extremity. Volunteers with scoliosis, spondylolisthesis, segmental disk space narrowing, and/or compression fractures in the radiographs were excluded. The fol...
Source: European Spine Journal - March 22, 2019 Category: Orthopaedics Source Type: research

Abnormal change of paravertebral muscle in adult degenerative scoliosis and its association with bony structural parameters
AbstractPurposeWhile many studies have explored the association between paravertebral muscle (PVM) change and low back pain/lumbar spinal stenosis, little is known about PVM change in adult degenerative scoliosis (ADS). The present study explored the PVM change in ADS and investigated its association with bony structural parameters.MethodsWe evaluated 78 patients in ADS without radiculopathy (ADS group) and 65 healthy persons without degenerative lumbar diseases (control group). Percentage of fat infiltration area (%FIA) of multifidus muscle at L1 to S1 disk level was measured by MRI, using ImageJ software. Lumbar scoliosi...
Source: European Spine Journal - March 21, 2019 Category: Orthopaedics Source Type: research

Hybrid stabilization of unstable osteoporotic thoracolumbar vertebral body fractures: clinical and radiological outcome after a mean of 4  years
ConclusionsThe majority of patients had low or moderate limitations and low to moderate reduction loss. Thereby, high loss of reduction correlated directly with inferior outcomes.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 21, 2019 Category: Orthopaedics Source Type: research

Primary vascular bone tumors in the spine: a challenge for pathologists and spine oncology surgeons
ConclusionsSurgeons must be aware of the evolution of terminology to decide the most appropriate treatment options.Graphical abstractThese slides can be retrieved from Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 21, 2019 Category: Orthopaedics Source Type: research

Biplanar stereoradiography predicts pulmonary function tests in adolescent idiopathic scoliosis: a cross-sectional study
AbstractPurposeVarious spinal and rib cage parameters measured from complex examinations were found to be correlated with preoperative pulmonary function tests (PFT). The aim was to investigate the relationship between preoperative rib cage parameters and PFT using biplanar stereoradiography in patients with severe adolescent idiopathic scoliosis.MethodsFifty-four patients, 45 girls and nine boys, aged 13.8  ± 1.2 years, with Lenke 1 or 2 thoracic scoliosis (>  50°) requiring surgical correction were prospectively included. All patients underwent preoperative PFT and low-dose biplana...
Source: European Spine Journal - March 20, 2019 Category: Orthopaedics Source Type: research

Spinal injuries in airborne accidents: a demographic overview of 148 patients in a level-1 trauma center
ConclusionDue to the increasing popularity of airborne sports, age of patients and severity of injuries (ISS) increased compared with the literature. The thoracolumbal spine is at especially high risk. To prevent further complications, the treatment procedure has to be sought carefully and algorithm should be introduced in clinics to avoid delay in diagnostics and surgery.Level of evidenceIII, retrospective comparative study.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 18, 2019 Category: Orthopaedics Source Type: research

Age- and sex-related changes in facet orientation and tropism in lower lumbar spine: an MRI study of 600 patients
AbstractPurposeWe aimed to determine the age- and sex-related changes in facet orientation and facet tropism in lower lumbar spine.MethodsBetween June 2015 and December 2017, magnetic resonance imaging scans of the consecutive 600 patients performed in the outpatient department for low back pain were analyzed. The data were divided according to age into four groups: group A (  60 years). The orientation of the facet angles at L3–4, L4–5 and L5–S1 was measured using the method described by Noren et al. Sagittal angles and tropism were determined at each level.ResultsAverage facet angle is noted...
Source: European Spine Journal - March 18, 2019 Category: Orthopaedics Source Type: research

The association between sacroiliac joint-related pain following lumbar spine surgery and spinopelvic parameters: a prospective multicenter study
ConclusionsThe incidence of postoperative SIJP after lumbar spine surgery was 3.0%. Higher PI values were associated with a higher risk of postoperative SIJP.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 18, 2019 Category: Orthopaedics Source Type: research

Reliability and validity of self-reported questionnaires to measure pain and disability in adults with neck pain and its associated disorders: part 3 —a systematic review from the CADRE Collaboration
ConclusionThe evidence supporting the validity and reliability of instruments used to measure pain and disability is preliminary. Further validity studies are needed to confirm the clinical utility of self-reported questionnaires to assess pain and disability in patients with NAD.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 16, 2019 Category: Orthopaedics Source Type: research

Surgical treatment of type II odontoid fractures in elderly patients: a comparison of anterior odontoid screw fixation and posterior atlantoaxial fusion using the Magerl –Gallie technique
ConclusionsOdontoid screw fixation is a less invasive surgery for type II B odontoid fractures in elderly patients. However, posterior atlantoaxial fusion provides a superior surgical outcome regarding fracture healing and the need for surgical revisions.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 16, 2019 Category: Orthopaedics Source Type: research

Prediction of brace effect in scoliotic patients: blinded evaluation of a novel brace simulator —an observational cross-sectional study
ConclusionsIncorporating high-fidelity copy of the entire 3D shape of the patient ’s trunk and multiple 3D-reconstructed bony images into an anatomical reference avatar resulted in moderate-to-good prediction of brace effect in three quarters of patients.Graphical abstract These slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 16, 2019 Category: Orthopaedics Source Type: research

Back pain and sagittal spine alignment in obese patients eligible for bariatric surgery
ConclusionsObese patients demonstrated lower functional performance compared with their non-obese counterparts, while cervical lordosis was diminished and the cSVA was increased in obese patients.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 15, 2019 Category: Orthopaedics Source Type: research

Minimum clinically important difference in outcome scores among patients undergoing cervical laminoplasty
ConclusionThe MCIDs of four outcome measures were determined for patients undergoing cervical laminoplasty.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 14, 2019 Category: Orthopaedics Source Type: research

Fully automated radiological analysis of spinal disorders and deformities: a deep learning approach
ConclusionsThe proposed method is able to automatically determine the spine shape in biplanar radiographs and calculate anatomical and posture parameters in a wide scenario of clinical conditions with a very good visual performance, despite limitations highlighted by the statistical analysis of the results.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 12, 2019 Category: Orthopaedics Source Type: research

Effect of needle diameter, type and volume of contrast agent on intervertebral disc degeneration in rats with discography
AbstractPurposeDiscography can increase disc degeneration, but the influence of different discography variables on the degeneration of discs has not been reported. The aim of this study was to investigate the effects of discography variables of needle diameter, type of contrast agent and volume of contrast agent on disc degeneration.MethodsThree separate experiments examined needle diameter, and type and volume of contrast agent. Coccygeal discs (Co7-10) adult male rats were used. X-rays were used to detect the disc height degeneration index at 1, 2 and 4  weeks after the procedure. MRI was used to study the changes i...
Source: European Spine Journal - March 12, 2019 Category: Orthopaedics Source Type: research

Letter to the Editor concerning “The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders” by Toyoda H, et al. (Eur Spine J; https://doi.org/10.1007/s00586-018-5858-8)
(Source: European Spine Journal)
Source: European Spine Journal - March 12, 2019 Category: Orthopaedics Source Type: research

Impact of pelvic incidence on change in lumbo-pelvic sagittal alignment between sitting and standing positions
ConclusionsChange in lumbo-pelvic parameters between the sitting and standing positions correlated with PI.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 11, 2019 Category: Orthopaedics Source Type: research

A validated preoperative score for predicting 30-day readmission after 1 –2 level elective posterior lumbar fusion
AbstractPurposeTo develop a model to predict 30-day readmission rates in elective 1 –2 level posterior lumbar spine fusion (PSF) patients.MethodsIn this retrospective case control study, patients were identified in the State Inpatient Database using ICD-9 codes. Data were queried for 30-day readmission, as well as demographic and surgical data. Patients were randomly assigned to either the derivation or the validation cohort. Stepwise multivariate analysis was conducted on the derivation cohort to predict 30-day readmission. Readmission after posterior spinal fusion (RAPSF) score was created by including variables wi...
Source: European Spine Journal - March 9, 2019 Category: Orthopaedics Source Type: research

Prevalence of and factors associated with dysfunctional low back pain in patients with rheumatoid arthritis
AbstractPurposeTo investigate the prevalence of and factors associated with dysfunctional low back pain (LBP) in patients with rheumatoid arthritis (RA).MethodsThis cross-sectional study included 1276 RA outpatients from two hospitals. The Roland –Morris Disability Questionnaire was used to address the functional–dysfunctional state criterion. Clinical variables, such as medical status, disease activity, bone mineral density, and spinopelvic alignment parameters, were compared between patients with and without dysfunctional LBP.ResultsMean age and disease duration were 64.6 and 13.4  years, respectively; t...
Source: European Spine Journal - March 8, 2019 Category: Orthopaedics Source Type: research

Predicting lowest hemoglobin level and risk of blood transfusion in spinal fusion surgery for adolescent idiopathic scoliosis
ConclusionsWe identified clear patient-specific perioperative parameters that affect risk of perioperative blood transfusion, including Cobb angle, PABD and preoperative Hb. Hb measurement beyond postoperative Day 3 is considered unnecessary unless clinically indicated.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 8, 2019 Category: Orthopaedics Source Type: research

Surgical growth guidance with non-fused anchoring segments in early-onset scoliosis
AbstractPurposeSurgical treatment of early-onset scoliosis (EOS) requires a balance between maintained curve correction and the capacity for spinal and thoracic growth. Spinal fusion creates irreversible conditions that prevent the implementation of further treatment methods. Our hypothesis was that non-fused anchors in growth guidance show a comparable outcome as the technique described in the literature, which involves spondylodesis of the anchoring segments.MethodsThis retrospective study analysed 148 surgeries in 22 EOS patients (11 female, 11 male) over a 15-year period. Patients underwent surgery with non-fused ancho...
Source: European Spine Journal - March 8, 2019 Category: Orthopaedics Source Type: research

Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study
ConclusionDisc AF cells exhibit distinct responses to serum and nutrient deprivation. Cellular responses include cell death and quiescence in addition to reduced proliferation and metabolic activity, as well as activation of autophagy under conditions of nutritional stress.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 7, 2019 Category: Orthopaedics Source Type: research

Adult spinal deformity surgical decision-making score
AbstractPurposeWe aimed to develop and internally validate a simple scoring system: the adult spinal deformity (ASD) surgical decision-making (ASD-SDM) score, which is specific to the decision-making process for ASD patients aged below 40  years.MethodsA multicentre prospective ASD database was retrospectively reviewed. The scoring system was developed using data from a derivation cohort and was internally validated in a validation cohort. The accuracy of the ASD-SDM score was assessed using the area under the receiver operating characteristic curve (AUC).ResultsA total of 316 patients were randomly divided into deriv...
Source: European Spine Journal - March 7, 2019 Category: Orthopaedics Source Type: research

Announcement
(Source: European Spine Journal)
Source: European Spine Journal - March 7, 2019 Category: Orthopaedics Source Type: research

Answer to the Letter to the Editor concerning “The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders” by Toyoda H, et al. (Eur Spine J; doi.org/10.1007/s00586-018-5858-8)
(Source: European Spine Journal)
Source: European Spine Journal - March 6, 2019 Category: Orthopaedics Source Type: research

Evaluation of an increased strut porosity silicate-substituted calcium phosphate, SiCaP  EP, as a synthetic bone graft substitute in spinal fusion surgery: a prospective, open-label study
ConclusionsEnhanced strut porosity SiCaP EP provided high (month 12: 86.3%) spinal fusion success rates in PLF surgery. Fusion success was associated with improved clinical outcomes in patients within 12  months, relative to baseline.ClinicalTrials.gov identifierNCT01452022Graphical abstractThese slides can be retrieved under Electronic Supplementary Material. (Source: European Spine Journal)
Source: European Spine Journal - March 5, 2019 Category: Orthopaedics Source Type: research