How Juul Hooked Kids and Ignited a Public Health Crisis

In the Scheetz household, back-to-school anxiety reached new heights this fall. Jami Scheetz’s 15-year-old son Devon, who has severe asthma, kicked a brutal vaping habit over the summer, with help from a nicotine patch. But as soon as school started and he was once again around kids vaping, his habit returned. On Sept. 12, Devon vaped at school and immediately began sweating and vomiting. Though Scheetz, who lives in Sellersville, Pa., says her son is now fine, she can’t shake thoughts of kids who have been hospitalized or died after using e-cigarettes. “Vaping scares me more [than smoking], because they don’t know what’s really in it,” she says. To a remarkable degree, a single company is front and center in one of the biggest public-health crises facing the country: the sharp rise in vaping among teenagers and young adults. In 2018, 30% of the nation’s 12th-graders reported vaping nicotine at least once in the past year, according to a January 2019 study sponsored by the National Institute on Drug Abuse. The study said the increase in vaping last year was “the largest ever recorded for any substance in the 44 years” that it has tracked adolescent drug use. Photograph by Jamie Chung for TIME Though Juul is not the only e-cigarette for sale in the U.S., it is largely blamed for the vaping explosion and controls about 50% of the market, putting a sharp focus on the company. On Sept. 9, the Food and Drug Administration sen...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized vaping Source Type: news

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ConclusionsIn this study, we showed TEW-7197 and ramucirumab considerably decreased invasiveness, thus EMTness in a panel of diffuse-type GC cell lines including GC PDCs. Taken together, we confirmed that combination of TEW-7197 and ramucirumab reduced tumor spheroid and GC PDC-induced blood vessel formation concomitantly in the spheroid-on-a-chip model.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: RESEARCH ARTICLE Source Type: research
AbstractBehavioral traits like aggression, anxiety, and trainability differ significantly across dog breeds and are highly heritable. However, the neural bases of these differences are unknown. Here we analyzed structural MRI scans of 62 dogs in relation to breed-average scores for the 14 major dimensions in the Canine Behavioral Assessment and Research Questionnaire, a well-validated measure of canine temperament. Several behavior categories showed significant relationships with morphologically covarying gray matter networks and regional volume changes. Networks involved in social processing and the flight-or-fight respon...
Source: Anatomy and Embryology - Category: Anatomy Source Type: research
The objective of the study was to explore the effect of the PARK16 rs11240572 variant on brain structure in PD patients. A total of 51 PD patients were enrolled in the study and genotyped for the rs11240572 variant. Clinical assessments and MRI scans were conducted across all participants. Voxel-based morphometry (VBM) was used to investigate gray matter volume (GMV) of the whole brain between these two groups. Correlation analysis was performed to identify the relationships between GMV and clinical features. There were 17 rs11240572-A variant carriers and 34 non-carriers, with no significant demographic differences betwee...
Source: Anatomy and Embryology - Category: Anatomy Source Type: research
In conclusion, the study showed that the novel RDI metric is sensitive to density of small and large axons in adults and children, with both single- and multi-shell acquis ition DWI data. Its effectiveness and availability to be used on standard as well as advanced DWI acquisitions makes it a promising method in clinical settings.
Source: Anatomy and Embryology - Category: Anatomy Source Type: research
Systematically mapping the mechanical properties of skin and tissue is useful for biomechanics research and disease diagnostics. For example, later stage breast cancer and lymphoma manifest themselves as hard nodes under the skin. Currently, mechanical measurements are done manually, with a sense of touch or a handheld tool. Manual measurements do not provide quantitative information and vary depending on the skill of the practitioner. Research shows that tactile sensors could be more sensitive than a hand. We propose a method that uses our previously developed skin-crawling robots to noninvasively test the mechanical prop...
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Conclusion: The differential characteristics of EDA contributed highly to the accuracy of pain stimulation level detection of the classifiers. The external validity dataset was not considered in the study. Significance: Our approach has the potential for accurate pain quantification using EDA.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
David J. BierThe Biden administrationis planning to roll out a  new policy in November that denies the right to travel or immigrate to the United States to anyone in the world who is unvaccinated. It will replace various nonsensical travel bans on Europeans, Chinese, Iranians, Brazilians, South Africans, and Indians, but a majority of the world (57 percent) has not received even a  single shot of any of the vaccines, andonly 1.9 percent of people in low ‐​income countries have received at least one dose. This includes pretty much the entire continent of Africa.Currently, everyone —vaccinated or not...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
New J. Chem., 2021, Accepted Manuscript DOI: 10.1039/D1NJ03533A, PaperLucie Melounkov á, Miriam Syková, Robert Jirásko, Roman Jambor, Radim Havelek, Eva Peterova, Jan Honzicek, Jaromír Vinklárek Two series of heterobimetallic compounds were prepared from the starting complex [cis-L2PtCl2] containing aminophosphine ligand (L = 2,6-iPr2-C6H3-NHPPh2). They cover neutral Pt-Sn complexes [cis-L2PtX(SnCl3)] (X = Cl, SnCl3) and ionic... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Analyst, 2021, Advance Article DOI: 10.1039/D1AN00938A, PaperWei Zhang, Ioannis Karagiannidis, Eliane De Santana Van Vliet, Ruoxin Yao, Ellen J. Beswick, Anhong Zhou Raman spectra acquired from a single living cell were analyzed by a machine learning based algorithm and transformed into aggressiveness score, and further paired with gene expression data for correlation analysis. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
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