Hacking The Nervous System

(Photo: © Job Boot) One nerve connects your vital organs, sensing and shaping your health. If we learn to control it, the future of medicine will be electric.When Maria Vrind, a former gymnast from Volendam in the Netherlands, found that the only way she could put her socks on in the morning was to lie on her back with her feet in the air, she had to accept that things had reached a crisis point. “I had become so stiff I couldn’t stand up,” she says. “It was a great shock because I’m such an active person.”It was 1993. Vrind was in her late 40s and working two jobs, athletics coach and a carer for disabled people, but her condition now began taking over her life. “I had to stop my jobs and look for another one as I became increasingly disabled myself.” By the time she was diagnosed, seven years later, she was in severe pain and couldn’t walk any more. Her knees, ankles, wrists, elbows and shoulder joints were hot and inflamed. It was rheumatoid arthritis, a common but incurable autoimmune disorder in which the body attacks its own cells, in this case the lining of the joints, producing chronic inflammation and bone deformity.Waiting rooms outside rheumatoid arthritis clinics used to be full of people in wheelchairs. That doesn’t happen as much now because of a new wave of drugs called biopharmaceuticals – such as highly targeted, genetically engineered proteins – which can really help. Not everyon...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

Related Links:

CONCLUSIONS: Based on these results, 8.1% of Mexican general population without a history of liver disease is at high risk of having advanced liver fibrosis and complications and death derived from cardiovascular disease and cirrhosis. Most of them showed normal ALT serum levels. PMID: 32063504 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Authors: Meunier L, Larrey D Abstract Some drugs may induce hepatotoxic lesions, such as steatosis or steatohepatitis found in Non-Alcoholic Fatty Liver Disease (NAFLD). Among these drugs there are some anti-tumoral molecules, such as methotrexate, 5-fluorouracil, irinotecan, tamoxifen and l-asparaginase. The hepatotoxic phenotype developed from treatment with such drugs is known as "CASH" for "Chemotherapy-induced Acute Steatohepatitis". The mechanism of toxicity is essentially based on mitochondrial toxicity. These lesions are chronic and often reversible when the treatment is stopped. Contrib...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Conclusions: LLH of the rectum with persistent symptoms or the endoscopic appearance of the nodular or SMT-like type may lead to clinically significant disease. Risk stratification according to endoscopic findings and careful surveillance are required for these lesions. PMID: 32062874 [PubMed - as supplied by publisher]
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
ConclusionLET is a rare cutaneous lupus-specific lesion that may be associated with SLE. AITD, hypothyroidism in particular, could be an initial presentation of SLE. Increased awareness and early diagnosis of such clinical presentations may improve patient outcomes.
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
The objective of this research article was to assess the trend of hospitalization, epidemiological characteristics and economic burden in the young adult, aged 18–45 years, presenting with atrial fibrillation.MethodsHospitalization data from the National Inpatient Sample between 2005 and 2015 were used to analyze prevalence of risk factors and financial burden in young adults with atrial fibrillation.ResultsFrom 2005 to 2015, a total of 260,080 admissions were included in the study. From 2005 to 2015, there was a decreasing trend of total admissions with atrial fibrillation among the age group of 18–45 years co...
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
The publisher regrets that the author information was incorrect in the footnote. This has been corrected for the online version. The correct information is “Worapol Ngamcherdtrakul, PhD, is a scientist at PDX Pharmaceuticals. Dr. Ngamcherdtrakul's research is focused on developing nanoparticles for cancer-targeted co-delivery of drug and siRNA and developing topical formulations of a nanotechnology for skin diseases. He also leads the cancer immunoth erapy program at PDX Pharmaceuticals”.
Source: Translational Research - Category: Research Authors: Tags: Erratum Source Type: research
CONCLUSIONS: Despite its limitations, the present meta-analysis found no clear differences in patient morbidity between the different flap designs. PMID: 32062667 [PubMed - as supplied by publisher]
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research
Treatment of unresectable hepatocellular carcinoma (HCC) is complex, and there is limited consensus on the optimal nonsurgical management strategy. This is further complicated by new technologies and locoregional therapies (LRTs) that continue to evolve over time. Several medical specialists are involved in HCC diagnosis and treatment, and treatment strategies are often dictated by consulting physicians ’ specialties, rather than by evidence-based consensus. The most recent National Comprehensive Cancer Network Clinical Practice Guidelines recommend ablation approaches for tumors 5 cm in size (1).
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Commentary Source Type: research
We read with interest the article by Manchec and colleagues (1), which correlated outcomes following catheter-directed thrombolysis of acute submassive pulmonary embolus with the anesthetic agents used for procedural sedation. It is commendable to see a review of cases in this emerging and still high-risk area of hospital practice. Any information that can contribute to successful rescue from pulmonary embolus will be welcomed by clinicians.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
Gena Cook learned to swim three months before competing in her first triathlon. She was 40. Not only did she not drown, she finished in the top five in her age group. “It is an example of the challenges I have sought to stretch me, that helped me take the biggest risk of all in starting Navigating Cancer,” she said. “I left behind all the comforts of a secure, well-paying job for the simple reason that I wanted to improve patient care for cancer patients. ” Navigating Cancer, which Cook…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
More News: Advertising | Anesthesia | Anesthesiology | Arthritis | Asthma | Autoimmune Disease | Babies | Babies Heart Conditions | Back Pain | Brain | Brain Cancers | Brain Tumor | Burns | Cancer | Cancer & Oncology | Cardiology | Cardiovascular | Cardiovascular & Thoracic Surgery | Chemotherapy | Chronic Fatigue Syndrome | Chronic Pain | Clinical Trials | Depression | Diabetes | Disability | Eating Disorders & Weight Management | Electrocardiogram | Endocrinology | Epilepsy | Gastric (Stomach) Cancer | Genetics | Girls | Health | Heart | Heart Attack | Hospital Management | Hospitals | Inflammatory Bowel Disease | International Medicine & Public Health | Jobs | Learning | Liver | Men | Methotrexate | Mitochondria | Neurology | Neuroscience | Neurosurgery | Obesity | Pain | Psychology | Rheumatoid Arthritis | Rheumatology | Science | Sports Medicine | Stroke | Study | Teaching | Toxic Shock Syndrome | Toxicology | Training | Universities & Medical Training | Urology & Nephrology | Websites