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New weakness found in most common childhood malignant brain tumor
(Queen Mary University of London) A new weakness found in medulloblastoma, the most common form of childhood brain tumor, could lead to more personalized medicine and improved treatment for some patients, according to an early study by Queen Mary University of London. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 5, 2017 Category: Cancer & Oncology Source Type: news

Insightec wins FDA nod for Exablate Neuro glioblastoma trial
Insightec said today it won FDA approval to launch a safety and feasibility trial of its Exablate Neuro, testing its ability to disrupt the blood brain barrier in patients with glioblastoma. The Exablate Neuro device, which won FDA approval last July for treating essential tremor, uses high-intensity, focused ultrasound to thermally ablate targeted tissue, guided by continuous magnetic resonance imaging; the procedure can be performed non-invasively through an intact skull. In the trial, a research team will inject commonly used a sonographic microbubble solution into the bloodstream of a patient with a malignant...
Source: Mass Device - November 28, 2017 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Food & Drug Administration (FDA) Neurological INSIGHTEC Source Type: news

London girl who had brain tumour now doing cartwheels
Indigo McGregor, from London, deteriorated as the growth pressed against her brain stem and was forced to use a wheelchair. But she made an amazing recovery after live-saving surgery. (Source: the Mail online | Health)
Source: the Mail online | Health - November 28, 2017 Category: Consumer Health News Source Type: news

Girl who had brain tumour now doing cartwheels
Indigo McGregor, from London, deteriorated as the growth pressed against her brain stem and was forced to use a wheelchair. But she made an amazing recovery after live-saving surgery. (Source: the Mail online | Health)
Source: the Mail online | Health - November 28, 2017 Category: Consumer Health News Source Type: news

Cancer drug starts clinical trials in human brain-cancer patients
(University of Illinois at Urbana-Champaign) A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of human patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the brain. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 27, 2017 Category: Cancer & Oncology Source Type: news

Promising target for treating brain tumors in children
(Ann& Robert H. Lurie Children's Hospital of Chicago) Findings published in Oncotarget offer new hope for children with highly aggressive brain tumors like atypical teratoid/rhabdoid tumor (AT/RT) and medulloblastoma. Previously, the authors of the study have shown that an experimental drug that inhibits polo-like kinase 4 (PLK4) stopped pediatric brain tumor growth in vitro. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 27, 2017 Category: International Medicine & Public Health Source Type: news

Henry Marsh: 'Ukraine is like a Trabant that wants to be a Ferrari'
Henry Marsh is a celebrated neurosurgeon who travels the world teaching his exacting craft. Robert McCrum joins him in Ukraine as he tries to save the life of 11-year-old ViktoriaWe joined the green-gowned brain surgery team soon after daybreak. The chill of the operating theatre was filled with the inevitable frisson of nerves before a big op. Inside the Orlika Street children ’s hospital in the suburbs ofLviv, on the western edge of Ukraine, the patient was waiting for us, under halogen lights, anaesthetised upon the table.She was corpse-like in unconsciousness. Her chilled cerise fingernails offered a poignant rem...
Source: Guardian Unlimited Science - November 26, 2017 Category: Science Authors: Robert McCrum Tags: Neuroscience Ukraine Medicine Education Source Type: news

WATCH: 4-year-old girl receives hundreds of books for Lena's Library while battling brain cancer
Lena Tietjen has received hundreds of packages filled with books for her own reading library while she begins to receive treatment and care for an inoperable malignant brain tumor. (Source: ABC News: Health)
Source: ABC News: Health - November 22, 2017 Category: Consumer Health News Tags: Lifestyle Source Type: news

That Time A Researcher Wished His Brain Tumor Had A Share Button
Why one researcher and data evangelist wishes he could more easily share the data that was collected in during his own brain surgery. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - November 21, 2017 Category: Pharmaceuticals Authors: Matthew Herper, Forbes Staff Source Type: news

Ziopharm says its brain cancer drug helped trial patients live more than a year
A Boston biotech with a unique approach to treating an aggressive brain tumor, Ziopharm Oncology reported this weekend that its combination of experimental drugs has helped 15 patients survive about twice as long as they would have otherwise in an early-stage trial. Ziopharm (Nasdaq: ZIOP) reported the updated trial data in patients with recurrent glioblastoma at the Society for Neuro-Oncology this weekend. The 15 patients are all being treated with Ziopharm’s gene therapy, called Ad-RTS-hIL-12,… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 20, 2017 Category: Biotechnology Authors: Don Seiffert Source Type: news

Childhood Brain Tumor Atypical Teratoid Rhabdoid
Childhood Brain Tumor: Atypical Teratoid/Rhabdoid (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 17, 2017 Category: General Medicine Source Type: news

Brain cancer treatment previously featured on 60 Minutes now available to children
(Solving Kids' Cancer) A Phase 1 clinical trial leveraging the re-engineered polio virus is now open for enrollment to children 12 years and older at the Preston Robert Tisch Brain Tumor Center, Duke University Medical Center. After years of following the progress of this promising therapy against adult glioblastoma and working with the research team on behalf of children, Solving Kids' Cancer teamed up with The Andrew McDonough B+ Foundation to help move this forward in a trial for pediatric brain tumor patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 16, 2017 Category: Cancer & Oncology Source Type: news

Tools to help you with brain tumour fatigue
The Brainstrust has launched a resource to help allied health professionals support people living with a brain tumour who are suffering from fatigue. (Source: NHS Networks)
Source: NHS Networks - November 14, 2017 Category: UK Health Source Type: news

SPM in Real Life: Fall ‘17
NEW MEMBERS: Fall ‘17 Brief bios/plugs for new members (extracted from the Introduce Yourself Connect Community) After returning to school to become an OR surgical tech, Mary Mack’s heart health declined, and she quickly learned to become a strong advocate for herself. Feeling that no one was into her participatory style, Mary believes a radical change in medical student education is necessary to change the culture of medicine. She is passionate about helping to make that change happen. Her other interests include playing the guitar and speaking Mandarin Chinese. Jim Skinner created the Smart Patient Academy a...
Source: Society for Participatory Medicine - November 13, 2017 Category: General Medicine Authors: Nanette Mattox Tags: Newsletter Source Type: news

Medical News Today: Deadly brain tumors halted by blocking telomere protein
By blocking TRF1, a protein involved in the protection of telomeres, researchers were able to halt the growth of glioblastoma tumors in mice. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 13, 2017 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

The first effective therapy against glioblastoma by attacking telomeres
(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) Researchers at the Spanish National Cancer Research Centre (CNIO) have shown that it is possible to block the growth of human and murine glioblastoma in mouse models by blocking the TRF1 protein; an essential component of the telomere-protective complex. The study, published in Cancer Cell, describes a new and promising way to combat this type of brain tumor by attacking its ability to regenerate and divide immortally. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 13, 2017 Category: Cancer & Oncology Source Type: news

25% of high-grade glioma patients alive 3 years post trial
Patients with recurrent high-grade glioma were treated by the University of Minnesota Medical School. Median survival was 14.4 months, compared with the typical 8 months. (Source: the Mail online | Health)
Source: the Mail online | Health - November 7, 2017 Category: Consumer Health News Source Type: news

Mysterious cluster of a rare, deadly childhood brain tumor that has cropped up in one Mississippi town could be tied to Hurricane Katrina
(Natural News) A very rare form of a fatal childhood brain tumor has mysteriously cropped up in a small Mississippi community, afflicting at least three kids since 2009 and puzzling medical investigators who only now think they may have a link. As reported by the U.K.’s Daily Mail, Sophia Myers, 7, was the latest child diagnosed... (Source: NaturalNews.com)
Source: NaturalNews.com - November 6, 2017 Category: Consumer Health News Source Type: news

Science Saturday: Brain tumors hijack growth proteins
What makes some brain cancers so hard to treat? Researchers in the laboratory of Alfredo Qui?ones-Hinojosa, M.D., Chair of Neurologic Surgery on Mayo Clinic?s campus in Florida, looked at devastating brain tumors known as chordomas to understand why those tumors are capable of growing so aggressively. In a study published in Cell Reports, they found [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 4, 2017 Category: Databases & Libraries Source Type: news

Florida boy diagnosed with brain tumor after concussion
Logan Silva, seven, was diagnosed with medulloblastoma, a fast-growing brain tumor. After getting a concussion, the boy from Florida suffered extreme headaches which turned out to be a tumor. (Source: the Mail online | Health)
Source: the Mail online | Health - November 2, 2017 Category: Consumer Health News Source Type: news

Onalespib could be an effective treatment for glioblastoma, preclinical studies show
This study showed that the targeted drug onalespib reduced the expression of cell-survival proteins such as AKT and endothelial growth factor receptor in glioma cell lines and glioma stem cells from patient tumors. This, in turn, reduced the survival, proliferation, invasion and migration of the cells. In animal models of glioblastoma the agent crossed the blood-brain barrier and showed effectiveness as a single agent and greater effectiveness in combination with temozolomide. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 2, 2017 Category: International Medicine & Public Health Source Type: news

25% of high-grade glioma patients live 3 years after trail
Patients with recurrent high-grade glioma were treated by the University of Minnesota Medical School. Median survival was 14.4 months, compared with the typical 8 months. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2017 Category: Consumer Health News Source Type: news

Brain tumour's 'addiction' to common amino acid could be its weakness
(Queen Mary University of London) Starving a childhood brain tumour of the amino acid glutamine could improve the effect of chemotherapy, according to an early study led by Queen Mary University of London (QMUL) and funded by Children with Cancer UK and the Medical Research Council. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 1, 2017 Category: Cancer & Oncology Source Type: news

Gene Therapy May Fight Brain Cancer's Return
FRIDAY, Oct. 27, 2017 -- A new form of gene therapy shows promise in battling recurrent brain cancer. The phase 1 clinical trial included 56 patients with recurrent high-grade glioma brain cancer. Three years after the gene therapy treatment, more... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 27, 2017 Category: General Medicine Source Type: news

An experimental model might shed new light on the development of brain cancer in children
(DZNE - German Center for Neurodegenerative Diseases) Researchers of the German Center for Neurodegenerative Diseases (DZNE) present in the journal Cancer Cell a novel laboratory model that replicates key hallmarks of pediatric high-grade glioma. Results might pave the way for a better understanding of processes, relevant for both cancer and neurodegeneration. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 27, 2017 Category: International Medicine & Public Health Source Type: news

Cancer trial led by University of Minnesota Medical School's Dr. Clark Chen shows promise
(University of Minnesota Medical School) New data from a Phase I clinical trial led by Clark Chen, M.D., Ph.D., Lyle French Chair in Neurosurgery and Head of the University of Minnesota Medical School Department of Neurosurgery shows more than a quarter of patients with recurrent high-grade glioma, a form of brain cancer, were alive more than three years after treatment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 27, 2017 Category: Cancer & Oncology Source Type: news

Boston Start-Up Hopes To Revolutionize Online Check-Ups
BOSTON (CBS) – We’ve all done it — felt an ache or pain and jumped online to diagnosis ourselves.  Those internet answers can be scary and flat-out wrong. A Boston start-up now wants to change the way we give ourselves these online check-ups. “You’ll hear people say all the time ‘I put in cough and I got lung cancer. I put in headache and I had a brain tumor,’ ” said Andrew Le, describing the possible results someone might get when googling their own symptoms. Le is CEO of Boston-based BuoyHealth.com, a new website that wants to be your first online stop when you&rs...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 26, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Dr. Mallika Marshall Source Type: news

Woman's leaking nipples were caused by a brain tumour  
When her symptoms worsened even after she came off the pill, Kirsty Lane, 26, from Weeting, Suffolk, insisted on a blood test, which revealed she was suffering from a brain tumour. (Source: the Mail online | Health)
Source: the Mail online | Health - October 25, 2017 Category: Consumer Health News Source Type: news

Brain tumors share common tricks to survive
(Cancer Research UK) Different types of brain tumors may use strikingly similar approaches to generate and use energy to survive in the brain. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 25, 2017 Category: Cancer & Oncology Source Type: news

Massachusetts boy dies of cancer 9 months after diagnosis
Devin Suau was a healthy six-year-old from Massachusetts when he fell off his snowboard in early February. A brain scan to check for concussion revealed an inoperable brain tumor. (Source: the Mail online | Health)
Source: the Mail online | Health - October 21, 2017 Category: Consumer Health News Source Type: news

Living With Cancer: Treating brain tumors
Brain tumors: Diagnosis and treatment? Brain tumors can begin in your brain (primary brain tumors), or cancer can begin in other parts of your body and spread to your brain (secondary, or metastatic, brain tumors). Treatment options depend on the type, size and location of the tumor, as well as your overall health and preferences. [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 20, 2017 Category: Databases & Libraries Source Type: news

Glioblastoma, brain tumour that took Gord Downie's life, tough to treat, doctors say
The passing of singer-songwriter Gord Downie also puts a spotlight on the need for more funding for research into the form of brain cancer that about 1,000 Canadians are diagnosed with every year. (Source: CBC | Health)
Source: CBC | Health - October 19, 2017 Category: Consumer Health News Tags: News/Health Source Type: news

Cancer: TOXIC arsenic treatment could triple life expectancy of brain tumour patients
TOXIC arsenic could be used as cheap treatment for a rare brain cancer, in a bid to triple life expectancy after diagnosis. (Source: Daily Express - Health)
Source: Daily Express - Health - October 18, 2017 Category: Consumer Health News Source Type: news

Therapeutic form of arsenic is a potential treatment for deadly type of brain cancer
(The Translational Genomics Research Institute) In a study led by Northwestern University Feinberg School of Medicine and the Translational Genomics Research Institute (TGen), this anti-cancer agent is being considered for use against glioblastoma multiforme (GBM), the most common and aggressive type of deadly brain tumors. The study was published today in Molecular Cancer Research, a journal of the American Association for Cancer Research (AACR). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 17, 2017 Category: Cancer & Oncology Source Type: news

Research to explore the development of deadly brain tumors
(University of Plymouth) A team led by Dr Claudia Barros from the Plymouth University Peninsula Schools of Medicine and Dentistry has secured £ 163,066 funding from the Brain Research Trust to explore the formation and development of cancer stem cells in glioblastoma -- the most common of malign brain tumours in adults and for which there is no cure. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 16, 2017 Category: Biology Source Type: news

Biology of childhood brain tumor subtypes offers clues to precision treatments
(Children's Hospital of Philadelphia) Researchers investigating pediatric low-grade gliomas (PLGG), the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer. By shedding light on subtle distinctions in tumor biology, these findings offer clues to designing more effective anticancer treatments to precisely target tumors in individual patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 16, 2017 Category: Cancer & Oncology Source Type: news

New York teen finds panic attacks caused by brain tumor
Chasin Mizrahi thought he was having panic attacks for six years before he was diagnosed with a brain tumor. The 19-year-old from Buffalo, New York is now free of the tumor, attacks, and therapy. (Source: the Mail online | Health)
Source: the Mail online | Health - October 13, 2017 Category: Consumer Health News Source Type: news

'My brain tumour was the size of an orange': Brain tumour survivor recounts her close-call
A ROUTINE test to check out her blurred vision revealed Michelle Crawford had a condition that could have killed her within months (Source: Daily Express - Health)
Source: Daily Express - Health - October 10, 2017 Category: Consumer Health News Source Type: news

Combination treatment targeting glucose in advanced brain cancer shows promising results in preclinical study
UCLA HealthPositron emission tomography images show glioblastoma tumor glucose uptake before, left, and after treatment in mice.FINDINGSUCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by David Nathanson, a member of UCLA ’s Jonsson Comprehensive Cancer Center, found that the drug combination tested in mice disrupts and exploits glucose intake, essentially cutting off the tumor’s nutrients and energy supply. This treatment then stimulates cell death pathways — which control the cancer cells’ fat...
Source: UCLA Newsroom: Health Sciences - October 9, 2017 Category: Universities & Medical Training Source Type: news

Areas of glioblastoma tumors correlate with separate subtypes of glioma stem cells
(University Hospitals Cleveland Medical Center) Study demonstrates, for the first time, that glioblastoma (GBM) is driven by two distinct subsets of cancer stem cells. Moreover, each subtype of glioma stem cells is driven by distinct transcriptional programs for growth and treatment resistance. The subsets also responded better to combination treatment in the mouse model. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 9, 2017 Category: Cancer & Oncology Source Type: news

Researchers recommend organic food and vitamins for pregnant women to reduce the risk of cancer and autism
(Natural News) Researchers of a new gestational analysis said that exposure to pesticides during pregnancy raises the baby’s risk of developing brain tumors. To reach this conclusion, the researchers conducted phone interviews with about 3,500 children below 15 years from two previous tests. Four hundred and thirty seven of the study subjects had brain cancer. “Our... (Source: NaturalNews.com)
Source: NaturalNews.com - October 7, 2017 Category: Consumer Health News Source Type: news

Weekly Postings
See something of interest? Please share our postings with colleagues in your institutions! Spotlight The University of Pittsburgh Health Sciences Library System (HSLS) invites applications for the newly created position of All of Us Community Engagement Coordinator for the Middle Atlantic Region of the National Network of Libraries of Medicine (NNLM MAR). View the full posting for more information about the position. Renew your membership today! If you have not yet verified that your organization’s record is up-to-date, see our recent blog post about the benefits of renewal and NNLM Membership. Are you having trouble...
Source: NN/LM Middle Atlantic Region Blog - October 6, 2017 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Weekly Postings Source Type: news

Eat organic during pregnancy to prevent brain tumours
Researchers from the French Institute of Health and Medical Research found exposure to chemicals commonly sprayed on to crops raises the risk of childhood brain cancers by 1.4 times. (Source: the Mail online | Health)
Source: the Mail online | Health - October 5, 2017 Category: Consumer Health News Source Type: news

Scientists enlist supercomputers, machine learning to automatically identify brain tumors
(University of Texas at Austin, Texas Advanced Computing Center) Researchers from The University of Texas at Austin developed a brain tumor identification method that combines biophysical models of tumor growth with machine learning algorithms. The researchers scored in the top 25% of participants in the Multimodal Brain Tumor Segmentation Challenge 2017 (BRaTS'17) and used supercomputers at the Texas Advanced Computing Center to accelerate the training and analysis process. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 5, 2017 Category: International Medicine & Public Health Source Type: news

Brain tumours: Pregnant mothers around THIS could be increasing kids’ risk of growths
PESTICIDES could encourage brain tumours to grow in children, a report claims. (Source: Daily Express - Health)
Source: Daily Express - Health - October 4, 2017 Category: Consumer Health News Source Type: news

UNF student creates interactive tumors in virtual reality
Jason Smith extended his hand and took hold of nothing. He twisted the empty air, positioning it just so. A thick pair of black goggles strapped to Smith's head revealed what lookers-on could not see: A malignant tumor nearly the size of his palm. The goggles, dubbed VRvisu, are a virtual reality headset designed and created by Smith, a senior at the University of North Florida. Using the headset, me dical professionals can see 3-D renderings of 16 brain tumors. The virtual tumors were recreated… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - October 4, 2017 Category: Health Management Authors: Will Robinson Source Type: news

UNF student creates interactive tumors in virtual reality
Jason Smith extended his hand and took hold of nothing. He twisted the empty air, positioning it just so. A thick pair of black goggles strapped to Smith's head revealed what lookers-on could not see: A malignant tumor nearly the size of his palm. The goggles, dubbed VRvisu, are a virtual reality headset designed and created by Smith, a senior at the University of North Florida. Using the headset, me dical professionals can see 3-D renderings of 16 brain tumors. The virtual tumors were recreated… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 4, 2017 Category: Biotechnology Authors: Will Robinson Source Type: news

Questions asked after three Mississippi kids get rare DIPG
Sophia Myers, 7, was diagnosed with DIPG, an incurable brain tumor, in February. She is the third child in eight years to be diagnosed with the rare cancer in Ocean Springs, Mississippi. (Source: the Mail online | Health)
Source: the Mail online | Health - October 3, 2017 Category: Consumer Health News Source Type: news

Cancer DIPG incurable child brain tumor Mississippi
Sophia Myers, 7, was diagnosed with DIPG, an incurable brain tumor, in February. She is the third child in eight years to be diagnosed with the rare cancer in Ocean Springs, Mississippi. (Source: the Mail online | Health)
Source: the Mail online | Health - October 3, 2017 Category: Consumer Health News Source Type: news

Pesticide use during pregnancy linked to increased risk of childhood brain tumors
(Wiley) Previous epidemiological studies have suggested that exposure to pesticides during pregnancy may have a possible role in the development of childhood brain tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 3, 2017 Category: International Medicine & Public Health Source Type: news