' Remarkable' Results for Targeted Therapy of Rare CNS Tumors'Remarkable' Results for Targeted Therapy of Rare CNS Tumors
The results come from three small studies of targeted therapy for papillary craniopharyngiomas (PCPs), gliomas and neuroblastomas.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 16, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Yale Cancer Center study reveals new pathway for brain tumor therapy
(Yale University) In a new study led by Yale Cancer Center, researchers show the nucleoside transporter ENT2 may offer an unexpected path to circumventing the blood-brain barrier (BBB) and enabling targeted treatment of brain tumors with a cell-penetrating anti-DNA autoantibody. The study was published today online in the Journal of Clinical Investigation Insight. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 15, 2021 Category: Cancer & Oncology Source Type: news

Novel radiopharmaceutical tracks 'master switch' protein responsible for cancer growth
This study was presented at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 14, 2021 Category: Cancer & Oncology Source Type: news

Japanese researcher developed a drug that uses a virus to attack brain tumor cells, say it could be applied to many other types of...
A Japanese researcher who developed a drug that uses a virus to attack brain tumor cells says it could be applied to many other types of cancer. (Source: Reuters: Health)
Source: Reuters: Health - June 13, 2021 Category: Consumer Health News Source Type: news

Her Sister Died of a Brain Tumor. Now She Was Having Similar Symptoms.
Humanity has planted flags on the moon, yet a moonshot for brain cancer has yet to be realized. (Source: NYT Health)
Source: NYT Health - June 11, 2021 Category: Consumer Health News Authors: Abdul-Kareem Ahmed, M.D. Tags: Brain Cancer Surgery and Surgeons Tumors Doctors Source Type: news

7T MRI visualizes sickle cell disease's effect on the brain
In a new study, 7-tesla MRI shows the often severe effects that sickle cel...Read more on AuntMinnie.comRelated Reading: Using fMRI to plan brain tumor resection boosts patient outcomes Cardiac MRI boosts myocarditis detection in college athletes 7-fold Bad hair day? Powdered hair products may pose problem for MRI Is mpMRI equally available to all men at risk of prostate cancer? AI enables noninvasive tumor pathology mapping on brain MRI (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 4, 2021 Category: Radiology Source Type: news

Using fMRI to plan brain tumor resection boosts patient outcomes
The use of preoperative functional MRI (fMRI) to plan brain tumor resectio...Read more on AuntMinnie.comRelated Reading: fMRI shows white-matter damage leads to worse cognitive outcomes fMRI gets to the bottom of smell, taste dysfunction from COVID-19 fMRI reveals info about visual conditions in stroke patients fMRI reveals why big games create lasting memories fMRI rates drop due to decrease in Medicare reimbursement (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 3, 2021 Category: Radiology Source Type: news

Recent research sheds light on link between meningiomas and seizures
Patients with the most common type of brain tumor and presenting with pre-operative seizures may benefit from more aggressive treatment, a Yale study finds. (Source: Yale Science and Health News)
Source: Yale Science and Health News - June 2, 2021 Category: Universities & Medical Training Source Type: news

Brain tumors caused by normal neuron activity in mice predisposed to such tumors
(Washington University School of Medicine) Researchers at Washington University School of Medicine in St. Louis and Stanford University School of Medicine have found that normal exposure to light can drive the formation and growth of optic nerve tumors in mice -- and maybe people -- with a genetic predisposition. Such tumors can lead to vision loss. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 26, 2021 Category: Cancer & Oncology Source Type: news

Engineered Immune Cells Eliminate Brain Cancer in Mice
Researchers developed a new CAR T-cell therapy that targets specific growth factor receptors in glioblastoma to eliminate brain tumors. (Source: The Scientist)
Source: The Scientist - May 25, 2021 Category: Science Tags: The Marketplace Source Type: news

How " paralyzed " immune cells can be reactivated against brain tumors
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor. These results confirm that therapeutic vaccines or immunotherapies are more effective against brain tumors if active substances are simultaneously used to promote the suppressed immune system. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 24, 2021 Category: Cancer & Oncology Source Type: news

The First dog of Finland has passed away
Sauli Niinistö and Jenni Haukio’s dog, a Boston terrier known as Lennu, has died of a brain tumour. (Source: Reuters: Health)
Source: Reuters: Health - May 22, 2021 Category: Consumer Health News Source Type: news

AI enables noninvasive tumor pathology mapping on brain MRI
Machine-learning models trained using autopsy tissue samples are revealing ne...Read more on AuntMinnie.comRelated Reading: Bedside point-of-care MRI appears convenient and accurate AI proves effective for triaging abnormal brain MRI results MRI profiles genomic characteristics of glioblastoma MRI at RSNA: COVID-19 and beyond Dual-phase technique improves PET/CT brain tumor imaging (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - May 20, 2021 Category: Radiology Source Type: news

Fitness-to-drive for glioblastoma patients: guidance from the Swiss Neuro-Oncology Society (SwissNOS) and the Swiss Society for Legal Medicine (SGRM) - Hofer S, Keller K, Imbach L, Roelcke U, Hutter G, Thomas H, Hertler C, Le Rhun E, Vasella F, Cordier D, Neidert M, Hottinger A, Migliorini D, Pflugshaupt T, Eggenberger N, Baumert B, L äubli H, Gramatzki D, Reinert M, Pesce G, Schucht P, Frank I, Lehnick D, Weiss T, Hans-Georg W, Wolpert F, Roth P, Weller M.
OBJECTIVE: The management of brain tumour patients who would like to resume driving is complex, and needs multidisciplinary input and a consensus among treating physicians. The Swiss Neuro-Oncology Society (SwissNOS) and the Swiss Society for Legal Medicin... (Source: SafetyLit)
Source: SafetyLit - May 20, 2021 Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news

Targeting abnormal cell metabolism shows promise for treating pediatric brain tumors
(Johns Hopkins Medicine) Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer. The findings were reported by Johns Hopkins Kimmel Cancer Center researchers in two published studies. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 20, 2021 Category: Cancer & Oncology Source Type: news

Advancing care for brain cancer: There ’s more work to be done
The odds of getting a malignant brain tumor are less than 1%. Yet if you or a family member happen to be among that small minority, the impact is powerful and devastating. Dr. Richard Curry, neuro-oncologist and director of neurology for the TriHealth Neuroscience Institute, takes pride in a brain tumor program atTriHealth’s Good Samaritan Hospital that was recently designated the first hospital in the Midwest to receive The Joint Commission’s Gold Seal of Appro val for Brain Tumor Certification.… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - May 18, 2021 Category: Health Management Authors: TriHealth Source Type: news

Advancing care for brain cancer: There ’s more work to be done
The odds of getting a malignant brain tumor are less than 1%. Yet if you or a family member happen to be among that small minority, the impact is powerful and devastating. Dr. Richard Curry, neuro-oncologist and director of neurology for the TriHealth Neuroscience Institute, takes pride in a brain tumor program atTriHealth’s Good Samaritan Hospital that was recently designated the first hospital in the Midwest to receive The Joint Commission’s Gold Seal of Appro val for Brain Tumor Certification.… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - May 18, 2021 Category: Biotechnology Authors: TriHealth Source Type: news

< a href= " /news-events/nih-research-matters/delivering-rna-therapies-brain-tumors " > Delivering RNA therapies to brain tumors < /a >
A combination of nanoparticle packaging and focused ultrasound allowed an RNA therapy to be delivered across the blood-brain barrier in mice. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - May 18, 2021 Category: Consumer Health News Source Type: news

Cancer symptoms: Five key signs a headache may be a sign of a brain tumour
CANCER cells multiplying in the brain amasses into a tumour. Taking up space inside of the skull, a headache is a "common symptom" of the disease, said Cancer Research UK. (Source: Daily Express - Health)
Source: Daily Express - Health - May 16, 2021 Category: Consumer Health News Source Type: news

Tumor-promoting immune cells retrained to fight most aggressive type of brain cancer
(Massachusetts General Hospital) Using a targeted antibody calledαGITR, tumor-promoting immune cells called regulatory T cells (Tregs) can be reprogrammed into cancer-killing immune cells in glioblastomas. Combining theαGITR antibody with immune-checkpoint-blocking drugs may benefit patients with glioblastomas, the most aggressive and uniformly fatal type of brain tumor. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 11, 2021 Category: International Medicine & Public Health Source Type: news

Breaching the blood-brain barrier to deliver precious payloads
(Georgia Institute of Technology) RNA-based drugs may change the standard of care for many diseases, making personalized medicine a reality. So far these cost-effective, easy-to-manufacture drugs haven't been very useful in treating brain tumors and other brain disease. But a team of researchers at Georgia Tech and Emory University has shown that a combination of ultrasound and RNA-loaded nanoparticles can temporarily open the protective blood-brain barrier, allowing the delivery of potent medicine to brain tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 7, 2021 Category: International Medicine & Public Health Source Type: news

Mayo Clinic Q & amp;A podcast: Brain Tumor Awareness Month
Primary brain tumors originate in the brain or tissues close to the brain, such as in brain-covering membranes, cranial nerves, or the pituitary or pineal glands. There are many types of primary brain tumors, and over 84,000 people will receive a primary brain tumor diagnosis in 2021, according to the National Brain Tumor Society. The median age [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 3, 2021 Category: Databases & Libraries Source Type: news

POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner
(Baylor College of Medicine) Researchers have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 19, 2021 Category: International Medicine & Public Health Source Type: news

Living near pesticide-treated farms raises risk of childhood brain tumors
(Natural News) Pregnant women living within 2.5 miles of agricultural lands treated with pesticides have a greater risk of their children developing central nervous system (CNS) tumors, according to a recent study. Published on Wednesday, March 31, in the Environmental Research journal, the study also revealed that the pregnant women did not have to be working in agriculture... (Source: NaturalNews.com)
Source: NaturalNews.com - April 17, 2021 Category: Consumer Health News Source Type: news

An ion pump to deliver chemotherapy agents to the brain
(Link ö ping University) Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumours. Researchers at Link ö ping University, Sweden, and the Medical University of Graz, Austria, have shown in cells in culture that an ion pump can deliver drugs more accurately, which gives less severe adverse effects in chemotherapy. The results have been published in Advanced Materials Technologies. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 15, 2021 Category: Biology Source Type: news

Woman with brain tumour fell pregnant before drugs would have made it impossible
Carly Beasley, 33, from Chippenham, Wiltshire, delayed her chemotherapy after her slow-growing, incurable brain tumour was removed so she could travel the world with her husband Kris, 34. (Source: the Mail online | Health)
Source: the Mail online | Health - April 14, 2021 Category: Consumer Health News Source Type: news

Australian researchers find new way to target deadly childhood cancer
(Children's Cancer Institute Australia) Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 14, 2021 Category: Cancer & Oncology Source Type: news

UAB makes progress on pediatric brain tumor study
UAB trial makes progress on brain tumor study. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - April 13, 2021 Category: Pharmaceuticals Authors: Tyler Patchen Source Type: news

UAB makes progress on pediatric brain tumor study
UAB trial makes progress on brain tumor study. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - April 13, 2021 Category: Biotechnology Authors: Tyler Patchen Source Type: news

Unusual treatment shows promise for kids with brain tumors
Scientists are reporting progress against a deadly type of childhood cancer with an unusual treatment (Source: ABC News: Health)
Source: ABC News: Health - April 12, 2021 Category: Consumer Health News Tags: Health Source Type: news

Deadly Brain Tumor: Survival Extended by Oncolytic Virus Product Deadly Brain Tumor: Survival Extended by Oncolytic Virus Product
Improved survival was seen in a small trial in which a genetically engineered version of herpes simplex virus was infused directly into high-grade gliomas.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Researchers discover new way to starve brain tumours
(Queen Mary University of London) Scientists from Queen Mary University of London, funded by the charity Brain Tumour Research, have found a new way to starve cancerous brain tumour cells of energy in order to prevent further growth. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 12, 2021 Category: Cancer & Oncology Source Type: news

CNIO scientists discovers a combination therapy for aggressive brain tumors
(Centro Nacional de Investigaciones Oncol ó gicas (CNIO)) * The researchers conducted an in-depth study of resistance to temozolomide, the first-line treatment for glioblastoma, to which many patients cease to respond over time* The combination of temozolomide and dianhydrogalactitol acts synergistically, overcomes this resistance and increases survival in mice with brain tumours* Treatments for glioblastoma have not improved in the last 20 years. The authors argue for the need to translate these results into clinical trials to study whether this combination therapy is also effective in patients with this disease (S...
Source: EurekAlert! - Cancer - April 12, 2021 Category: Cancer & Oncology Source Type: news

MD Anderson researchers highlight advances in clinical studies at the AACR Annual Meeting 2021
(University of Texas M. D. Anderson Cancer Center) Researchers at The University of Texas MD Anderson Cancer Center conducted early phase clinical trials that showed promising results for patients with RET fusion-positive cancers, high-grade and low-grade glioma and ovarian cancer. The results for these studies will be presented at the AACR Annual Meeting 2021. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 11, 2021 Category: Cancer & Oncology Source Type: news

Light shed on the coordination of neural stem cell activation
(Institut Pasteur) Scientists at the Institut Pasteur, CNRS, and Tel Aviv University working in collaboration with the É cole Polytechnique and INRAE have successfully performed 3D visualization and spatial and temporal distribution analysis of neural stem cell activation in the adult brain of a zebrafish vertebrate model.Their findings demonstrate for the first time that activation events for these cells are coordinated in time and space. In particular, these results may help improve our understanding of regulation processes triggered during brain tumor formation. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 8, 2021 Category: Biology Source Type: news

Paul Ritter, actor in 'Harry Potter' and 'Chernobyl,' dead at 54 after suffering brain tumor
Paul Ritter, known for the "Harry Potter" franchise and "Chernobyl" died at age 54. (Source: Reuters: Health)
Source: Reuters: Health - April 6, 2021 Category: Consumer Health News Source Type: news

'Harry Potter' Actor Paul Ritter Dies of Brain Tumor at 54
'Harry Potter" actor Paul Ritter dead at 54. (Source: Reuters: Health)
Source: Reuters: Health - April 6, 2021 Category: Consumer Health News Source Type: news

Vysioneer secures FDA clearance for brain tumor contouring software
The U.S. Food and Drug Administration (FDA) has cleared artificial intelligenc...Read more on AuntMinnie.comRelated Reading: Akesis radiation therapy system cleared Radformation releases rad therapy contouring software European Commission gives OK to big Siemens/Varian deal Hypofractionated radiotherapy helped England survive COVID-19 ViewRay posts mixed financial results for Q4, year (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 6, 2021 Category: Radiology Source Type: news

Christ Hospital, Mayfield Brain & Spine announce new partnership
Two of the region ’s most recognized health care providers are partnering to enhance care for patients with brain tumors and other brain diseases. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - April 5, 2021 Category: Biotechnology Authors: Liz Engel Source Type: news

She Suffered Balance Issues for Years. Was It a Brain Tumor?
A visit to the dentist unexpectedly led to a resolution. (Source: NYT Health)
Source: NYT Health - March 31, 2021 Category: Consumer Health News Authors: Lisa Sanders, M.D. Tags: Ears and Hearing Vertigo Brain Tumors Source Type: news

Mother, 53, claims four years of IVF left her with a life-threatening brain tumour
Serena Jardine, from Worthing in Sussex, became dizzy and forgetful in 2014, six years after she first had IVF, and was soon diagnosed with a non-cancerous meningioma brain tumour. (Source: the Mail online | Health)
Source: the Mail online | Health - March 29, 2021 Category: Consumer Health News Source Type: news

Metformin trial dramatically reduces seizures in tuberous sclerosis
(University College London) A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin - a drug commonly used to treat Type 2 diabetes - can successfully reduce symptoms associated with tuberous sclerosis complex (TSC), including reduction in the frequency of seizures and the size of brain tumours. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2021 Category: International Medicine & Public Health Source Type: news

Upstate Cancer Center introduces multidisciplinary team for brain tumor patients
Program incorporates radiation oncology, neurosurgery and medical oncology. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - March 26, 2021 Category: Universities & Medical Training Tags: News Source Type: news

Vaccination against mutated protein tested in brain tumor patients for the first time
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) Tumor vaccines can help the body fight cancer. Mutations in the tumor genome often lead to protein changes that are typical of cancer. A vaccine can alert the patients' immune system to these mutated proteins. For the first time, physicians and cancer researchers from Heidelberg and Mannheim have now carried out a clinical trial to test a mutation-specific vaccine against malignant brain tumors. The vaccine proved to be safe and triggered the desired immune response in the tumor tissue. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 24, 2021 Category: Cancer & Oncology Source Type: news

New anti-cancer therapy: Converting glioma cells into neurons
(Guangdong-Hongkong-Macau Institute of CNS Regeneration,Jinan University) Glioma is a fatal neurological disorder that has limited interventional treatment, despite extensive research over the past several decades. A research team led by Dr. Gong Chen,has developed a novel gene therapy to reprogram glioma cells into functional neurons, shedding new light on glioma treatment. The work has been published in Cancer Biology& Medicine on March 22, 2021 (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 23, 2021 Category: Cancer & Oncology Source Type: news

ATRT molecular groups: looking at the biology from the clinic
(St. Jude Children's Research Hospital) Scientists at St. Jude Children's Research Hospital are learning more about what the molecular groups of a rare pediatric brain tumor mean for clinical care. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 18, 2021 Category: Cancer & Oncology Source Type: news

Simple blood test could replace surgery for some brain tumour patients
(University of Plymouth) Researchers at the Brain Tumour Research Centre of Excellence at the University of Plymouth have discovered a biomarker which helps to distinguish whether meningioma - the most common form of adult primary brain tumour - is grade I or grade II. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 17, 2021 Category: Cancer & Oncology Source Type: news

Special Collection: Brain tumour diagnosis and management
Cochrane Library Special Collections provide a round-up of up-to-date Cochrane evidence on a specific topic.This Special Collection provides evidence in several key clinical priority areas for brain tumour research.  The reviews in this Collectionprovide evidence towards clinical priority areas for research, and their funding, and therefore, are important for consumers, clinicians, healthcare providers and funders.Topics include:Diagnosing brain tumours quickly, safely, and accuratelyRisk-sharing in decision making for brain tumoursBest treatment when decisions are difficult When asked about the new Special Colle...
Source: Cochrane News and Events - March 12, 2021 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Weight Gain Common in Childhood Brain Tumor Survivors Weight Gain Common in Childhood Brain Tumor Survivors
Children treated for brain tumors experienced significant weight gain and had a high rate of hypothalamic-pituitary dysfunction.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 12, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Five University of Colorado Cancer Center researchers receive grants to study brain tumors
(University of Colorado Anschutz Medical Campus) Three projects from University of Colorado Cancer Center researchers have received grants from the Denver-based Michele Plachy-Rubin Fund for Pilot Grants in Brain Cancer Research. Receiving $40,000 each to fund their work around brain cancer are Sujatha Venkataraman, PhD; and the teams of Philip Reigan, PhD, and Michael Graner, PhD; and Natalie Serkova, PhD, and Nicholas Foreman, MD, MBChB. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 10, 2021 Category: Cancer & Oncology Source Type: news