Researchers identify novel potential combination therapy for childhood brain tumors
(Write Science Right) Brazilian researchers working in collaboration with Canadian scientists demonstrated that all medulloblastoma tumor subtypes express two stem cell markers: BMI1 and CD133. When they induced DNA chromatin relaxation, tumor cell viability was reduced with down-regulation of BMI1 and CD133. These anti-tumor effects could be potentiated by concurrent inhibition of MAPK/ERK signaling. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 20, 2020 Category: Cancer & Oncology Source Type: news

British Woman Plays Violin While Doctors Remove Brain Tumor
Dagmar Turner, whose performance was caught on video, said the thought of losing her ability to play was "heart-breaking.” (Source: Science - The Huffington Post)
Source: Science - The Huffington Post - February 19, 2020 Category: Science Source Type: news

Violinist plays Mahler and Gershwin as surgeons remove brain tumour
A patient at a British hospital played Mahler and Gershwin on the violin while a tumour was removed from her brain so that surgeons could preserve her ability to play music and honour her 40-year passion for the instrument. (Source: CBC | Health)
Source: CBC | Health - February 19, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

Violinist plays Mahler and Gershwin to save her music as surgeons remove brain tumour
A patient at a British hospital played Mahler and Gershwin on the violin while a tumour was removed from her brain so that surgeons could preserve her ability to play music and her 40-year passion for the instrument. (Source: Reuters: Health)
Source: Reuters: Health - February 19, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

ZAP Surgical to Bring World-Class Brain Tumor Treatments to Rural German Hospital
Bonifatius Hospital in Lingen to Be Among the First in Europe to Offer the Latest Advances in Stereotactic Radiosurgery SAN CARLOS, Calif., Feb. 19, 2020 -- (Healthcare Sales & Marketing Network) -- ZAP Surgical Systems, Inc. today announced an agreeme... Devices, Oncology, Neurosurgery ZAP Surgical Systems, ZAP-X, stereotactic, radiosurgery, radiotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 19, 2020 Category: Pharmaceuticals Source Type: news

Patient plays violin during her brain surgery
Professional musician Dagmar Turner was diagnosed with a large brain tumour in 2013. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - February 19, 2020 Category: Consumer Health News Source Type: news

U.K. Patient Plays Violin During Unusual Brain Tumor Surgery
(LONDON) — Surgeons at King’s College Hospital in London removed a brain tumor from a woman who played the violin during the procedure. Doctors for violinist Dagmar Turner, 53, mapped her brain before the surgery to identify areas that were active when she played the instrument and those responsible for controlling language and movement. Doctors then woke her in mid-procedure so she could play to “ensure the surgeons did not damage any crucial areas of the brain that controlled Dagmar’s delicate hand movements,” the hospital said in a statement. “We knew how important the violin is to Da...
Source: TIME: Health - February 19, 2020 Category: Consumer Health News Authors: Associated Press Tags: Uncategorized health onetime United Kingdom Source Type: news

Combination drug therapy for childhood brain tumors shows promise in laboratory models
(Johns Hopkins Medicine) In experiments with human cells and mice, researchers at the Johns Hopkins Kimmel Cancer Center report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called trametinib may be more effective than either drug alone in decreasing the growth of pediatric low-grade gliomas. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 17, 2020 Category: International Medicine & Public Health Source Type: news

Scientists find ally in fight against brain tumors: Ebola
One of the world ’s deadliest viruses may be useful in treating one of the deadliest of brain cancers, finds a new Yale study. (Source: Yale Science and Health News)
Source: Yale Science and Health News - February 12, 2020 Category: Universities & Medical Training Source Type: news

Scientists find ally in fight against brain tumors: Ebola
Glioblastomas are relentless, hard-to-treat, and often lethal brain tumors. Yale scientists have enlisted a most unlikely ally in efforts to treat this form of cancer - elements of the Ebola virus. "The irony is that one of the world's deadliest viruses may be useful in treating one of the deadliest of brain cancers," said Yale's Anthony van den Pol, professor of neurosurgery, who describes the Yale efforts Feb. 12 in the Journal of Virology. (Source: World Pharma News)
Source: World Pharma News - February 12, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Scientists find ally in fight against brain tumors: Ebola
(Yale University) Glioblastomas are relentless, hard-to-treat, and often lethal brain tumors. Yale scientists have enlisted a most unlikely ally in efforts to treat this form of cancer -- elements of the Ebola virus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 12, 2020 Category: International Medicine & Public Health Source Type: news

Glioma Trials Should Track Living Well, Not Just Longer Glioma Trials Should Track Living Well, Not Just Longer
Neuro-oncology working group backs focus on how patients feel, function.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 11, 2020 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Removing Tissue Surrounding Brain Tumor May Double Survival in Patients with Glioblastoma
The results presented in this study indicated that neurosurgeons may need to change how they approach tumor removal and, when safe, include non-contrast-enhancing tumor during resection achieve maximal resection. (Source: CancerNetwork)
Source: CancerNetwork - February 11, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Finding a cure for Fido's brain cancer may help us find a cure for ourselves
(Jackson Laboratory) For cancers such as glioma, preclinical research models have failed to provide sufficient insight for medical progress. A team led by Jackson Laboratory's Roel Verhaak thoroughly analyzed sporadic canine gliomas and found that their molecular characteristics, including gene mutations and duplications, resemble those of humans. The results indicate that dogs provide an effective model for human gliomas, and learning how to more effectively treat our pets will likely inform better prognoses for human patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 10, 2020 Category: Cancer & Oncology Source Type: news

More Aggressive Surgery Can Extend Survival From Brain Cancer: Study
FRIDAY, Feb. 7, 2020 -- Adults with glioblastoma -- the most common and deadly type of brain tumor -- could survive more than twice as long if surgeons removed surrounding tissue as well as the tumor, a new study finds. That involves cutting out... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 7, 2020 Category: General Medicine Source Type: news

More aggressive surgery may improve brain cancer survival
A new, more aggressive surgical approach may double survival rates in adults with brain tumors, a study published Thursday in the Journal JAMA Oncology has revealed. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 6, 2020 Category: Consumer Health News Source Type: news

Brain tumor surgery that pushes boundaries boosts patients survival
(University of California - San Francisco) Survival may more than double for adults with glioblastoma, the most common and deadly type of brain tumor, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 6, 2020 Category: Cancer & Oncology Source Type: news

New way to study pituitary tumors holds potential for better diagnoses and treatments
(Houston Methodist) Houston Methodist neurosurgeons are looking at a new way to classify pituitary tumors that could lead to more precise and accurate diagnosing for patients in the future. These tests also could have potential for better diagnoses in other brain tumors. The findings, published Jan. 28 in Scientific Reports, describe a new way to study the blood of pituitary adenoma patients to determine tumor type and whether they might respond to medical treatment rather than surgery. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 3, 2020 Category: International Medicine & Public Health Source Type: news

Nurse celebrates surviving brain cancer 10 YEARS after being told it was terminal 
Gemma Wensley, 37, of Exeter, Devon, even began planning her own funeral when she was told she had a inoperable brain tumour a decade ago. She said doctors don't know how she was so lucky. (Source: the Mail online | Health)
Source: the Mail online | Health - January 30, 2020 Category: Consumer Health News Source Type: news

Poliovirus therapy shows potential as cancer vaccine in lab studies
A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine. In preclinical studies using mice and human cancer cells, an injection of the modified poliovirus vector instigated an immune response that homed in on mutated cancer cells that predominate in diffuse midline glioma (DMG) tumors. The cancer strikes children and is universally deadly. (Source: World Pharma News)
Source: World Pharma News - January 30, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Poliovirus therapy shows potential as cancer vaccine in lab studies
(Duke University Medical Center) A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 30, 2020 Category: Biology Source Type: news

Organoids (in vitro brains) to study pediatric brain tumors
(Università di Trento) Hundreds of miniature brains were grown in the laboratories of the University of Trento to study the genetic mechanisms responsible for the most common brain cancer affecting children. The results of a collaborative research effort, coordinated by the University of Trento and carried out with Sapienza University and Ospedale pediatrico Bambino Ges ù in Rome and Irccs Neuromed, were published today in Nature Communications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 29, 2020 Category: International Medicine & Public Health Source Type: news

Brain tumors remodel neuronal synapses to promote growth
(Baylor College of Medicine) Scientists discovered that glioma, a lethal form of brain cancer, alters the activity of neighboring neurons, accelerating a vicious cycle that drives tumor-associated epilepsy and tumor progression. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: news

Image of the Day: Tumor Vasculature
Researchers use a cutting-edge technique to map the blood vessels of brain tumors as patients are awake during surgery with the hope of reducing damage to adjacent tissues. (Source: The Scientist)
Source: The Scientist - January 24, 2020 Category: Science Tags: Image of the Day Source Type: news

Immune system cells contribute to the invading capacity of brain tumours
(Universitat Autonoma de Barcelona) An article published in Brain Communications, coordinated by Carlos Barcia, researcher at Institut de Neuroci è ncies de la UAB, describes how the immune system facilitates the expansion of tumour cells in the brain. The study was performed on human samples of glioblastoma, the most aggressive brain tumour, and on cell culture models. These findings will help to develop treatments for this type of tumour, for which there is not an effective therapy at the moment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 23, 2020 Category: Cancer & Oncology Source Type: news

Immune system cells contribute to the invading capacity of brain tumors
(Universitat Autonoma de Barcelona) An article published in Brain Communications, coordinated by Carlos Barcia, researcher at Institut de Neuroci è ncies de la UAB, describes how the immune system facilitates the expansion of tumor cells in the brain. The study was performed on human samples of glioblastoma, the most aggressive brain tumor, and on cell culture models. These findings will help to develop treatments for this type of tumor, for which there is not an effective therapy at the moment. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 23, 2020 Category: Biology Source Type: news

Study uncovers unexpected connection between gliomas, neurodegenerative diseases
(Michigan Medicine - University of Michigan) New basic science and clinical research identifies TAU, the same protein studied in the development of Alzheimer's, as a biomarker for glioma development. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 22, 2020 Category: Cancer & Oncology Source Type: news

Taylor Swift's Mother Has Brain Tumor
While Taylor Swift's mother was undergoing treatment for breast cancer, doctors discovered that she also had a brain tumor (Source: WebMD Health)
Source: WebMD Health - January 21, 2020 Category: Consumer Health News Source Type: news

Woman, 22, suffering from psychosis was misdiagnosed as bi-polar before doctors found brain tumour
Laura Skerritt, from Templecombe, Somerset, was prescribed anti-depressants when she first visited doctors in 2017. But the drugs had no effect and brain scans revealed she had a giant tumour. (Source: the Mail online | Health)
Source: the Mail online | Health - January 20, 2020 Category: Consumer Health News Source Type: news

Improved brain chip for precision medicine
(University of Houston) The Akay Lab biomedical research team at the University of Houston is reporting an improvement on a microfluidic brain cancer chip previously developed in their lab. The new chip allows quick assessment of the effectiveness of cancer drugs on brain tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 16, 2020 Category: International Medicine & Public Health Source Type: news

Surgery May Add Years for Patients With Deadly Brain Cancer: Study
WEDNESDAY, Jan. 20, 2020 -- Surgical removal of the entire tumor may extend the lives of patients with a rare and deadly type of brain cancer called brainstem high-grade gliomas, a new study suggests. Researchers analyzed data from 103 patients in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 15, 2020 Category: General Medicine Source Type: news

Scientists breach brain barriers to attack tumors
(Yale University) The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. But protection comes at a cost: These barriers interfere with the immune system when faced with dire threats such glioblastoma, a deadly brain tumor for which there are few effective treatments. Yale researchers have found a novel way to circumvent the brain's natural defenses when they're counterproductive by slipping immune system rescuers through the fortresses' drainage system. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2020 Category: Cancer & Oncology Source Type: news

Meningeal lymphatic network: A new avenue in the treatment of brain tumors
(INSERM (Institut national de la sant é et de la recherche m é dicale)) Glioblastomas are the most common type of brain tumor, and their prognosis is often highly unfavorable. A collaborative study by Jean-L é on Thomas, Inserm researcher at the Brain& Spine Institute (Inserm/CNRS/Sorbonne Universit é ) and Piti é -Salp ê tri è re Hospital AP-HP, and Akiko Iwasaki (Department of Immunology, Yale University School of Medicine, USA), has revealed the beneficial role played by the meningeal lymphatic vascular network in treating these tumors -- in the short and longer term. ...
Source: EurekAlert! - Cancer - January 15, 2020 Category: Cancer & Oncology Source Type: news

AI Metrics joins forces with Imaging Biometrics
Artificial intelligence (AI) technology developer AI Metrics has signed advanced...Read more on AuntMinnie.comRelated Reading: Imaging Biometrics nets NIH grant Imaging Biometrics points to brain tumor study Imaging Biometrics teams with CorTechs Labs Imaging Biometrics debuts IB Server software Imaging Biometrics touts research paper on DSC MRI (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 14, 2020 Category: Radiology Source Type: news

CNS Pharmaceuticals Licenses DNA-Binding Agent from MD Anderson, Doubling its Drug Pipeline
HOUSTON, Jan. 13, 2020 -- (Healthcare Sales & Marketing Network) -- CNS Pharmaceuticals, Inc. (NASDAQ: CNSP) (“CNS” or the “Company”), a biotechnology company specializing in the development of novel treatments for brain tumors, today announced it has ent... Biopharmaceuticals, Oncology, Licensing CNS Pharmaceuticals, WP1244, blood-brain barrier (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 13, 2020 Category: Pharmaceuticals Source Type: news

Girl, 14, is diagnosed with killer brain tumour after doctors blamed puberty for crippling headaches
Lily Wythe, 14, from Southend-on-Sea, Essex, was told her debilitating migraines were a normal part of puberty. But an MRI revealed she had a DIPG tumour - which kills most patients within a year. (Source: the Mail online | Health)
Source: the Mail online | Health - January 9, 2020 Category: Consumer Health News Source Type: news

Peering into the genome of brain tumor
(Osaka University) Scientists at Osaka University have created a machine learning method for classifying the mutations of glioma brain tumors based on MR images alone. Thus far, classification has only been possible by tissue sampling during surgery. The new method is noninvasive, may remove the need for a tissue sample and help accelerate delivery of treatment for patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 9, 2020 Category: Cancer & Oncology Source Type: news

Nanoparticles deliver 'suicide gene' therapy to pediatric brain tumors growing in mice
(Johns Hopkins Medicine) Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a " suicide gene " to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test animals' survival. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 8, 2020 Category: International Medicine & Public Health Source Type: news

Brazilian scientists unveil chemotherapy resistance mechanism related to p53 mutation
(Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB)) Brazilian study uncovered an anticancer chemotherapy resistance mechanism related to amyloid aggregation of mutant p53. The research was conducted in cells derived from glioblastoma, a super aggressive brain tumor, and in living cells. The results open up new opportunities for the development of more effective therapies against cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 8, 2020 Category: Cancer & Oncology Source Type: news

Brain tumour research could help future precision medicine
New research on brain tumours could improve patient diagnosis and treatment options as part of a precision medicine approach. Brain tumours are the leading cause of cancer deaths in children and adults under the age of 40, with 16,000* people in the UK diagnosed with a brain tumour each year. (Source: University of Bristol news)
Source: University of Bristol news - January 7, 2020 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Translational Health Sciences; Press Release Source Type: news

A.I. Comes to the Operating Room
Images made by lasers and read by computers can help speed up the diagnosis of brain tumors during surgery. (Source: NYT)
Source: NYT - January 7, 2020 Category: American Health Authors: Denise Grady Tags: Brain Cancer Surgery and Surgeons Artificial Intelligence Tissue (Human) Tumors Nature Medicine (Journal) Laser (Light Amplification by Stimulated Emission of Radiation) Orringer, Daniel A your-feed-healthcare Source Type: news

Brain tumour research could help future precision medicine
(University of Bristol) New research on brain tumours could improve patient diagnosis and treatment options as part of a precision medicine approach. Brain tumours are the leading cause of cancer deaths in children and adults under the age of 40, with 16,000* people in the UK diagnosed with a brain tumour each year. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 7, 2020 Category: Cancer & Oncology Source Type: news

Brain tumor research could help future precision medicine
(University of Bristol) New research on brain tumors could improve patient diagnosis and treatment options as part of a precision medicine approach. Brain tumors are the leading cause of cancer deaths in children and adults under the age of 40, with 16,000 people in the UK diagnosed with a brain tumor each year. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 7, 2020 Category: Cancer & Oncology Source Type: news

Laser - Based Imaging + AI May Diagnose Brain Tumors in OR
Accurate diagnosis in (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 7, 2020 Category: Cancer & Oncology Tags: Neurology, Oncology, Pathology, Surgery, Journal, Source Type: news

Connecticut boy, seven, with fatal brain tumor spends last Christmas home
Trenton O'Brien, seven, of East Haven, Connecticut, was diagnosed with a brain tumor called Diffuse Intrinsic Pontine Glioma in June 2019. He's been home, in hospice care, since Christmas Eve. (Source: the Mail online | Health)
Source: the Mail online | Health - January 6, 2020 Category: Consumer Health News Source Type: news

Laser-Based Imaging & #43; AI May Diagnose Brain Tumors in OR
MONDAY, Jan. 6, 2020 -- A novel workflow that combines advanced optical imaging with an artificial intelligence algorithm may accurately diagnose brain tumors in real time in the operating room, according to a study published online Jan. 6 in Nature... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 6, 2020 Category: Pharmaceuticals Source Type: news

New imaging technique may speed diagnosis of brain tumors
Researchers are using artificial intelligence -- combined with advanced optical imaging -- to rapidly diagnose brain tumors. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 6, 2020 Category: Consumer Health News Source Type: news

AI can diagnose brain tumors better, faster and earlier than doctors can
A new study from NYU Langone Health has found that artificial intelligence can correctly diagnose brain tumors with 94.6% accuracy compared to 93.9% accuracy by doctors. (Source: the Mail online | Health)
Source: the Mail online | Health - January 6, 2020 Category: Consumer Health News Source Type: news

A.I. Comes to the Operating Room
Images made by lasers and read by computers can help speed up the diagnosis of brain tumors during surgery. (Source: NYT Health)
Source: NYT Health - January 6, 2020 Category: Consumer Health News Authors: Denise Grady Tags: Brain Cancer Surgery and Surgeons Artificial Intelligence Tissue (Human) Tumors Nature Medicine (Journal) Daniel A. Orringer Laser (Light Amplification by Stimulated Emission of Radiation) your-feed-healthcare Source Type: news

New imaging system and artificial intelligence algorithm accurately identify brain tumors
(NYU Langone Health / NYU School of Medicine) Study finds novel method of optical imaging combined with artificial intelligence accurately diagnoses brain tumors in real time. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 6, 2020 Category: International Medicine & Public Health Source Type: news