Novel Mesothelioma Treatment Closer to FDA Approval
Standard-of-care treatment for patients with pleural mesothelioma may soon include Tumor Treating Fields (TTF), a novel therapy involving electric currents that disrupt cancer cell division and inhibit tumor growth. In the wake of recently released results from Novocure’s STELLAR phase II clinical trial, the U.S. Food and Drug Administration (FDA) is expected to approve the treatment within the next six months, giving mesothelioma patients another much-needed option. “At this point, it should be a relatively rapid approval process,” Dr. Eilon Kirson, chief science officer at Novocure, the oncology company...
Source: Asbestos and Mesothelioma News - September 17, 2018 Category: Environmental Health Authors: Matt Mauney Source Type: news

Adult Survivors of Childhood Brain Tumors May Struggle to Live Independently Adult Survivors of Childhood Brain Tumors May Struggle to Live Independently
Adults who had brain cancer as children may have a harder time living independently and having rich professional and personal lives than people who didn't have these tumors in childhood, a U.S. study suggests.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Adult survivors of childhood brain tumors may struggle to live independently
(Reuters Health) - Adults who had brain cancer as children may have a harder time living independently and having rich professional and personal lives than people who didn't have these tumors in childhood, a U.S. study suggests. (Source: Reuters: Health)
Source: Reuters: Health - September 13, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

High-resolution genomic map gives scientists unprecedented view of brain development
(St. Jude Children's Research Hospital) The research will not only aid basic understanding of brain development, but also provide a foundation for understanding the cellular origins of brain disorders caused by errors in development. These anatomical defects include Joubert syndrome, Dandy-Walker malformation and pontocerebellar hypoplasia. The database will enable future studies tracing the cellular origins of childhood brain tumors such as medulloblastoma, astrocytoma and ependymoma.Researchers worldwide can interact with the data via an interface St. Jude has created called Cell Seek. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 13, 2018 Category: Biology Source Type: news

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma
A major limitation of targeted cancer therapy is the rapid emergence of drug resistance, which often arises through mutations at or downstream of the drug target or through intrinsic resistance of subpopulations of tumor cells. Medulloblastoma (MB), the most common pediatric brain tumor, is no exception, and MBs that are driven by sonic hedgehog (SHH) signaling are particularly aggressive and drug-resistant. To find new drug targets and therapeutics for MB that may be less susceptible to common resistance mechanisms, we used a developmental phosphoproteomics approach in murine granule neuron precursors (GNPs), the developm...
Source: Signal Transduction Knowledge Environment - September 11, 2018 Category: Science Authors: Purzner, T., Purzner, J., Buckstaff, T., Cozza, G., Gholamin, S., Rusert, J. M., Hartl, T. A., Sanders, J., Conley, N., Ge, X., Langan, M., Ramaswamy, V., Ellis, L., Litzenburger, U., Bolin, S., Theruvath, J., Nitta, R., Qi, L., Li, X.-N., Li, G., Taylor, Tags: STKE Research Articles Source Type: news

Barrow receives major grant to find cure for deadliest brain cancer
Thanks to a $50 million grant, Barrow Neurological Institute will create a new center to focus on finding a cure and improving outcomes for the deadliest form of brain cancer. The funding comes from the Ben and Catherine Ivy Foundation and will seed the Ivy Brain Tumor Center, which will accelerate drug discovery and clinical testing for glioblastoma. That is the form of brain cancer that killed Arizona Sen. John McCain. "This grant will fast track discovery and offer support and hope to those… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 10, 2018 Category: Pharmaceuticals Authors: Tim Gallen Source Type: news

Barrow receives largest grant in history to seek cure for deadly brain cancer
(St. Joseph's Hospital and Medical Center) Barrow Neurological Institute has initiated a $50 million effort, supported by the single largest research grant in the history of brain tumor research, to seek a cure for the deadliest form of brain cancer. Funding from The Ben and Catherine Ivy Foundation will be used to dramatically accelerate drug discovery and clinical testing for glioblastoma in the newly-formed Ivy Brain Tumor Center at the Barrow Neurological Institute. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 10, 2018 Category: International Medicine & Public Health Source Type: news

The boy whose clumsiness turned out to be cancer
Atticus Feduchin-Pate, from Whitchurch in Hampshire, has been diagnosed with a terminal high-grade cancer called diffuse intrinsic potine glioma which cannot be operated on. (Source: the Mail online | Health)
Source: the Mail online | Health - September 6, 2018 Category: Consumer Health News Source Type: news

Body's own 'bomb squad' can help protect against brain tumors
(eLife) Researchers have discovered how a molecule can help prevent certain types of brain tumors by recognizing and 'disarming' harmful proteins that cause them. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 4, 2018 Category: International Medicine & Public Health Source Type: news

Radiotherapy for Some Brain Tumors May Hamper New Memories in Kids Radiotherapy for Some Brain Tumors May Hamper New Memories in Kids
Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 31, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

UC neurosurgery chief building department with new hires
Dr. Joseph Cheng, who leads all neurosurgery activities at UC Health, has hired a half-dozen neurosurgeons in recent months to build the affiliated Department of Neurosurgery at the University of Cincinnati College of Medicine. And more faculty could be added soon. The neurosurgeons recruited by Cheng include experts in the areas of brain tumor, cerebrovascular, spinal and functional neurosurgery. They round out Cheng’s specialty in all aspects of spinal surgery, including treating degenerative… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 31, 2018 Category: Pharmaceuticals Authors: Barrett J. Brunsman Source Type: news

Cancer symptoms: Eight warning signs you could have a life-threatening brain tumour
BRAIN tumour symptoms can depend on the type of brain tumour - benign or malignant - and also what part of the brain has been affected. But there are six general signs to look out for from headaches to changes in personality. (Source: Daily Express - Health)
Source: Daily Express - Health - August 30, 2018 Category: Consumer Health News Source Type: news

Brain tumour symptoms: Eight warning signs of a life-threatening growth to watch for
BRAIN tumour symptoms can depend on the type of brain tumour - benign or malignant - and also what part of the brain has been affected. But there are six general signs to look out for from headaches to changes in personality. (Source: Daily Express - Health)
Source: Daily Express - Health - August 30, 2018 Category: Consumer Health News Source Type: news

Researchers to test individualized drug cocktails for kids' brain tumors
Using genomic technology, researchers are planning a clinical trial of individualized drug cocktails to treat children with a form of malignant brain tumor. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 30, 2018 Category: Consumer Health News Source Type: news

Brain tumour symptoms: Eight signs you could have a life-threatening growth
BRAIN tumour symptoms can depend on the type of brain tumour - benign or malignant - and also what part of the brain has been affected. But there are six general signs to look out for from headaches to changes in personality. (Source: Daily Express - Health)
Source: Daily Express - Health - August 30, 2018 Category: Consumer Health News Source Type: news

10 Questions for Maria Menounos
Maria Menounos talk about her career, health advice, and her experience with a brain tumor. (Source: WebMD Health)
Source: WebMD Health - August 28, 2018 Category: Consumer Health News Source Type: news

John McCain Hated the Affordable Care Act. He Also Saved It
This article originally appeared on Kaiser Health News (KHN), a nonprofit news service covering health issues. It is an editorially independent program of the Kaiser Family Foundation that is not affiliated with Kaiser Permanente. (Source: TIME: Health)
Source: TIME: Health - August 27, 2018 Category: Consumer Health News Authors: Emmarie Huetteman / Kaiser Health News Tags: Uncategorized Healthcare healthytime Source Type: news

Senator John McCain Dies From Brain Tumor
Title: Senator John McCain Dies From Brain TumorCategory: Health NewsCreated: 8/26/2018 12:00:00 AMLast Editorial Review: 8/27/2018 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - August 27, 2018 Category: Cancer & Oncology Source Type: news

Epigenetic analysis of aggressive brain tumors
(CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) Glioblastoma is a brain cancer with devastating prognosis. It is caused by numerous genetic defects, which make it difficult to treat. A new study by scientists from CeMM, MedUni Vienna and the Austrian Brain Tumor Registry network demonstrates how epigenetic analysis of tumor samples collected in routine clinical practice could be used to better classify and treat the disease. The results were published in Nature Medicine. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 27, 2018 Category: Cancer & Oncology Source Type: news

Study defines mechanisms behind focused-ultrasound-assisted treatment of brain tumors
(Massachusetts General Hospital) A study led by a team of Massachusetts General Hospital investigators has analyzed, for the first time, the mechanisms underlying the use of focused ultrasound to improve the delivery of anti-cancer drugs across the blood brain barrier into brain tumors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 27, 2018 Category: Cancer & Oncology Source Type: news

U.S. Sen. John McCain Dies Of Brain Cancer
In July 2017, doctors removed a blood clot above his left eye at the Mayo Clinic Hospital in Phoenix, AZ. During that procedure, they found a brain tumor known as glioblastoma associated with the clot. (Source: WebMD Health)
Source: WebMD Health - August 26, 2018 Category: Consumer Health News Source Type: news

What is glioblastoma?
Sen. John McCain died Saturday, more than a year after he was diagnosed with glioblastoma, an aggressive brain tumor. (Source: CNN.com - Health)
Source: CNN.com - Health - August 26, 2018 Category: Consumer Health News Source Type: news

Senator John McCain Dies From Brain Tumor
(Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - August 26, 2018 Category: Cancer & Oncology Source Type: news

McCain Stops Treatment for Brain Cancer
The family of Sen. John McCain announced Friday that that 81-year-old Republican would stop receiving treatment for a brain tumor. McCain was diagnosed with an aggressive form of cancer, a gliobloastoma, in July 2017. (Source: WebMD Health)
Source: WebMD Health - August 24, 2018 Category: Consumer Health News Source Type: news

John McCain No Longer Receiving Treatment for Terminal Brain Tumor
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - August 24, 2018 Category: Cancer & Oncology Tags: Nursing, Oncology, News, Source Type: news

How glioblastoma is treated
Glioblastoma, an aggressive type of cancer that can occur in the brain or spinal cord, quickly became a household term after Sen. John McCain was diagnosed with the brain tumor in July 2017. Thirteen months later, in August, he decided to discontinue treatment for the brain cancer. (Source: CNN.com - Health)
Source: CNN.com - Health - August 24, 2018 Category: Consumer Health News Source Type: news

John McCain No Longer Receiving Treatment for Terminal Brain Tumor
FRIDAY, Aug. 24, 2018 -- Senator John McCain's long battle with brain cancer may be nearing an end, with his family announcing Friday that he will no longer receive treatment for the condition. The 81-year-old Republican Arizona senator and hero of... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 24, 2018 Category: General Medicine Source Type: news

Teacher tells jokes and sings opera during nine-hour operation to remove her brain tumour
Sarah-May Philo, from Glasgow, lightened the mood in the operating room during her own brain surgery by singing opera classic Ave Maria and making up funny songs about people around her. (Source: the Mail online | Health)
Source: the Mail online | Health - August 24, 2018 Category: Consumer Health News Source Type: news

John McCain No Longer Receiving Treatment for Terminal Brain Tumor
(Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - August 24, 2018 Category: Cancer & Oncology Source Type: news

Non-Hispanic White Patients Have Higher Glioma Incidence Non-Hispanic White Patients Have Higher Glioma Incidence
Dr Laurie Barclay comments on a study that aimed to quantify the differences in incidence and survival in adults with glioma by race or ethnicity.Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 23, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news

Hormone deficiency in patients exposed to radiation therapy
The level of radiation exposure used to treat brain tumours is associated with hormone deficiency in young patients, according to a study published in theJournal of Clinical Oncology.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 23, 2018 Category: Endocrinology Source Type: news

I sang opera while surgeons removed my brain tumour
Comedian Sarah-May Philo sang and told jokes while a surgeon removed her life-threatening brain tumour (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 22, 2018 Category: Consumer Health News Source Type: news

Childhood Brain Tumor Radiation Can Hinder Memory
Radiation treatment for medulloblastoma, the most common type of childhood brain tumor, can leave young survivors struggling to remember recent events, a small study has found. But survivors' ability to recall things that happened before radiation wasn't affected. (Source: WebMD Health)
Source: WebMD Health - August 21, 2018 Category: Consumer Health News Source Type: news

Radiation for Childhood Brain Tumor Can Hinder Memory
(Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - August 21, 2018 Category: Psychiatry Tags: Family Medicine, Neurology, Oncology, Pediatrics, Psychiatry, News, Source Type: news

Radiation for Childhood Brain Tumor Can Hinder Memory
TUESDAY, Aug. 21, 2018 -- Radiation therapy for the most common childhood brain tumor can cause memory problems, new research suggests. Specifically, it can leave young survivors struggling to create memories of recent personal events, the small... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 21, 2018 Category: General Medicine Source Type: news

Radiation for Childhood Brain Tumor Can Hinder Memory
Title: Radiation for Childhood Brain Tumor Can Hinder MemoryCategory: Health NewsCreated: 8/21/2018 12:00:00 AMLast Editorial Review: 8/21/2018 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - August 21, 2018 Category: Cancer & Oncology Source Type: news

Radiation for Childhood Brain Tumor Can Hinder Memory
(Source: Cancercompass News: Other Cancer)
Source: Cancercompass News: Other Cancer - August 21, 2018 Category: Cancer & Oncology Source Type: news

Labourer has 18 months to live due to a rare cancer in his brain
Jordan Payne, 23, from Ripley in Derbyshire, is battling a golf ball-sized brain tumour that is made of germ cells - created as a foetus grows in the womb. They eventually become sperm or eggs. (Source: the Mail online | Health)
Source: the Mail online | Health - August 20, 2018 Category: Consumer Health News Source Type: news

Labourer, 23, has 18 months to live due to a rare tumour in his brain
Jordan Payne, 23, from Ripley in Derbyshire, is battling a golf ball-sized brain tumour that is made of germ cells - created as a foetus grows in the womb. They eventually become sperm or eggs. (Source: the Mail online | Health)
Source: the Mail online | Health - August 20, 2018 Category: Consumer Health News Source Type: news

Brain cancer potentially resists immunotherapies by trapping T cells in bone marrow
(Osaka University) Researchers in collaboration with Osaka University found that brain tumors in mice and humans cause immune T-cells to become trapped in bone marrow. This occurs prior to cancer treatment and explains the low circulating levels of T-cells seen in some tumor patients. The effects that brain tumors have on the cell surface S1P1 protein appear to mediate the process. These findings open the door for possible adjuvant cancer treatments. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 20, 2018 Category: Cancer & Oncology Source Type: news

Study details effect of radiation exposure on hormone deficiencies
(University of Cincinnati Academic Health Center) In a new study, University of Cincinnati (UC) researchers, in collaboration with Massachusetts General Hospital, have detailed the effect of radiation exposure on the development of hormone deficiency in pediatric and young adult patients treated for brain tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Children with brain tumors who undergo radiation less likely to recall recent events
(Baylor University) Children with certain types of brain tumors who undergo radiation treatment are less likely to recall the specifics of events they experienced after radiation than to remember pre-treatment happenings, according to a Baylor University study comparing them to children with healthy brains. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Childhood brain tumor treatment impairs new memory formation
(Society for Neuroscience) Young people who received radiation therapy for the most common pediatric brain tumor struggle to create new memories about specific events, according to a study of children and adolescents published in JNeurosci. Their ability to recall events prior to treatment, however, remains intact. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Chemical shows promise at killing glioblastoma cells in mouse studies
Researchers have identified a synthetic chemical, named KHS101, which causes the death of aggressive brain tumour cells from patients in laboratory tests. The researchers found that the synthetic chemical cut the energy source of glioblastoma tumour cells. (Source: Medical Research Council General News)
Source: Medical Research Council General News - August 16, 2018 Category: Research Source Type: news

Georgetown releases cache of brain cancer data
Georgetown Lombardi Comprehensive Cancer Center has released a set of brain...Read more on AuntMinnie.comRelated Reading: FLT-PET points toward survival for glioblastoma patients SNMMI: FET-PET could have answers for brainstem glioma PET/CT helps assess pediatric brain tumor therapy Brain MRI surprises with incidental findings SNMMI: FDOPA-PET/MRI monitors pediatric brain tumors (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 15, 2018 Category: Radiology Source Type: news

Scientists discover chemical which can kill glioblastoma cells
(University of Leeds) Aggressive brain tumour cells taken from patients self-destructed after being exposed to a chemical in laboratory tests, researchers have shown. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 15, 2018 Category: Cancer & Oncology Source Type: news

Girl, 14, dies of brain tumor after year-long court battle for chemo despite her parent's wishes
After months hospital compromises and months of legal battles, a court finally ordered that a 14-year-old Cleveland, Ohio girl needed chemo despite her parents wishes - but she died before getting it. (Source: the Mail online | Health)
Source: the Mail online | Health - August 13, 2018 Category: Consumer Health News Source Type: news

Duke team finds missing immune cells that could fight lethal brain tumors
(Duke University Medical Center) Researchers at Duke Cancer Institute have tracked the missing T-cells in glioblastoma patients. They found them in abundance in the bone marrow, locked away and unable to function because of a process the brain stimulates in response to glioblastoma, to other tumors that metastasize in the brain and even to injury. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 13, 2018 Category: Biology Source Type: news