Is CEM or breast MRI better for breast cancer diagnosis?
Which modality is better for breast cancer diagnosis, contrast-enhanced mammography or dynamic contrast-enhanced breast MRI? It depends on a variety of factors, according to a review published May 20 in Radiology Clinics. Ritse Mann, MD, PhD, of Radboud University Medical Center, Nijmegen, the Netherlands, and colleague Valentina Longo, MD, of Fondazione Policlinico Universitario in Rome, Italy, noted that, although CEM's performance is slightly less than MRI for diagnostic imaging of breast cancer, in "many situations [it is] a viable alternative." Mammography is the traditional modality for both screening for breast ca...
Source: AuntMinnie.com Headlines - May 22, 2024 Category: Radiology Authors: Kate Madden Yee Tags: MRI Breast Imaging Source Type: news

Regulator asks state bodies to limit scope of key cancer drug
India's drug regulatory authority has instructed state-level counterparts to mandate manufacturers of Olaparib tablets in 100 mg and 150 mg strengths to cease marketing the cancer medication for patients with advanced ovarian cancer and "gBRCA mutation" (genes associated with tumor suppression), who have undergone three or more rounds of prior chemotherapy treatment. (Source: The Economic Times)
Source: The Economic Times - May 21, 2024 Category: Consumer Health News Source Type: news

FDA OKs Novel BiTE Agent for Small Cell Lung Cancer
(MedPage Today) -- The FDA has granted accelerated approval to tarlatamab (Imdelltra) as a third-line option for patients with extensive-stage small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. Approval... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - May 17, 2024 Category: American Health Source Type: news

Atezolizumab Plus Chemo Falters in Rapidly Relapsing TNBC
(MedPage Today) -- Combining atezolizumab (Tecentriq) with chemotherapy for patients with rapidly relapsing, PD-L1-positive triple-negative breast cancer (TNBC) failed to significantly improve overall survival (OS) compared with chemotherapy alone... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - May 16, 2024 Category: Hematology Source Type: news

FDA grants accelerated approval to tarlatamab-dlle for extensive stage small cell lung cancer
On May 16, 2024, the Food and Drug Administration granted accelerated approval to tarlatamab-dlle (Imdelltra, Amgen, Inc.) for extensive stage small cell lung cancer (ES-SCLC) with disease progression on or after platinum-based chemotherapy. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 16, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Why Do Certain Patients With Pancreatic Cancer Skip Surgery? Why Do Certain Patients With Pancreatic Cancer Skip Surgery?
Weight loss during preoperative chemotherapy was one factor associated with reduced odds of undergoing surgical resection for pancreatic cancer.Medscape Medical News (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - May 16, 2024 Category: Surgery Tags: Hematology-Oncology Clinical Summary Source Type: news

Why Do Certain Patients With PDAC Forgo Surgery? Why Do Certain Patients With PDAC Forgo Surgery?
Weight loss during preoperative chemotherapy was one factor associated with reduced odds of undergoing surgical resection for pancreatic cancer.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 16, 2024 Category: Consumer Health News Tags: Hematology-Oncology Clinical Summary Source Type: news

Lymphoma: Know Your Treatment Options
THURSDAY, May 16, 2024 -- For anyone newly diagnosed with blood cancers known as lymphomas, their first question might be: What treatments can help? Of course, there have been big advances in chemotherapy against the disease, but treatments now go... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 16, 2024 Category: General Medicine Source Type: news

Immunotherapy Before and After Surgery Boosts Lung Cancer Survival
THURSDAY, May 16, 2024 -- Immunotherapy can boost the survival of early-stage lung cancer patients eligible for surgery when it’s combined with chemotherapy, a new clinical trial reports. Those who got immunotherapy before and after surgery... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 16, 2024 Category: General Medicine Source Type: news

Perioperative Nivolumab Boosts EFS in Resectable Lung Cancer
(MedPage Today) -- Adding nivolumab (Opdivo) to neoadjuvant chemotherapy followed by adjuvant treatment with the PD-1 inhibitor alone significantly increased event-free survival (EFS) for patients with resectable non-small cell lung cancer (NSCLC... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - May 16, 2024 Category: Hematology Source Type: news

King Charles cancer: Experts reveal why cancer patients lose taste after chemotherapy
EXCLUSIVE: This side effect can result in weight loss and even damage to your teeth and mouth, experts said. (Source: Daily Express - Health)
Source: Daily Express - Health - May 15, 2024 Category: Consumer Health News Source Type: news

ARRS: More chemo response details needed in breast MRI reporting
Several neoadjuvant chemotherapy response characteristics are often left out of breast MRI reports, suggest findings presented May 7 at the American Roentgen Ray Society (ARRS) annual meeting. In a talk delivered at the conference, Sheida Ebrahimi, MD, from the University of California, San Diego presented her team’s study, which showed that little to no reports indicate the timing of chemotherapy, changes in background parenchymal enhancement (BPE), and the type of response in the findings section. “This single-institution, quality improvement project suggests that there is an opportunity to improve the reporting of...
Source: AuntMinnie.com Headlines - May 15, 2024 Category: Radiology Authors: Amerigo Allegretto Tags: MRI Womens Imaging Source Type: news

Donepezil Flunks Test for Chemotherapy-Related Cognitive Impairment
(MedPage Today) -- The acetylcholinesterase inhibitor donepezil (Aricept) failed to improve chemotherapy-related cognitive impairment (CRCI) in breast cancer survivors, a placebo-controlled trial showed. After 24 weeks of treatment, performance... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - May 14, 2024 Category: Psychiatry Source Type: news

Novel inhibitor insights offer pathway to preventing PXR-associated drug resistance
Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize external chemicals, including drugs. This causes a significant drop in the effectiveness of chemotherapy, antivirals and other pharmaceuticals. Blocking the PXR activity is notoriously difficult, as many drugs that bind the protein, whether intentionally or unintentionally, activate it. Scientists at St. Jude Children’s Research Hospital have leveraged chemical and structural studies in the design of PXR inhibitors to better unde...
Source: World Pharma News - May 14, 2024 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Fighting lymphoma: Treatment options include alternatives to chemotherapy, expert explains
Editor's Note: May 28 is World Blood Cancer Day ROCHESTER, Minn. — Chemotherapy is usually the first treatment doctors try to treat lymphoma, including the two most common forms: non-Hodgkin and Hodgkin. But alternatives to chemotherapy are developing, as first-line treatments and as backup options, explains Stephen Ansell, M.D., Ph.D., hematology chair and hem atologic oncologist at the Mayo Clinic Comprehensive Cancer Center. Lymphoma is a blood cancer that begins when a germ-fighting white blood cell,… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 14, 2024 Category: Databases & Libraries Source Type: news