Platinum-containing chemotherapy for women before or after surgery for early triple-negative breast cancer
The Cochrane Breast Cancer Group have published reviews on more than 80 topics, and these were added to in September 2023 with a review of platinum-based chemotherapy for women with early stage triple negative breast cancer. In this podcast, Rachel Dear, co-author and breast cancer oncologist based in Sydney, talks with lead author, Sofia Mason from the Garvan Institute of Medical Research in Darlinghurst Australia about the findings. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - September 26, 2023 Category: General Medicine Authors: Cochrane Source Type: podcasts
Why bladder cancer cells that shed their Y chromosome become more aggressive
In this episode:00:45 Why losing the Y chromosome makes bladder cancer more aggressiveLoss of the Y chromosome in bladder cancer cells is associated with increased severity of disease, but the reasons behind this have been unclear. Now researchers show that the loss of this chromosome helps tumour cells evade the immune system. However, this mechanism also makes the cells more vulnerable to certain chemotherapy treatments, and the researchers hope their findings could help improve outcomes for patients in the future.Research article: Abdel-Hafiz et al.07:30 Research HighlightsHow pollution particles ferry influenza virus d...
Source: Nature Podcast - June 21, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts
Coordinated Care to Optimize Treatment in Patients With Diabetes and Cardiovascular Disease, Panitumumab vs Bevacizumab Added to Chemotherapy for Metastatic Colorectal Cancer, USPSTF Recommendation on Screening for Skin Cancer, and more
Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the April 18, 2023, issue. Related Content: Audio Highlights (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - April 18, 2023 Category: General Medicine Authors: JAMA Network Source Type: podcasts
JAMA Oncology : Adjuvant Chemotherapy in Patients With Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy
Interview with Marco Del Chiaro, MD, PhD, author of Association of Adjuvant Chemotherapy in Patients With Resected Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy. Hosted by Jack West, MD. Related Content: Association of Adjuvant Chemotherapy in Patients With Resected Pancreatic Adenocarcinoma After Multiagent Neoadjuvant Chemotherapy (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - December 8, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
Radiotherapy With vs Without Chemotherapy for Nasopharyngeal Carcinoma, Trends in Lipids Concentrations in US Adults, USPSTF Recommendation Statement on Statin Use, and more
Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief of JAMA, the Journal of the American Medical Association, for the August 23/30, 2022 issue. (Source: JAMA: This Week's Audio Commentary)
Source: JAMA: This Week's Audio Commentary - August 23, 2022 Category: General Medicine Authors: JAMA Network Source Type: podcasts
JAMA Oncology : Guideline-Concordant Surgery and Adjuvant Chemotherapy Among Patients With Early-Stage Lung Cancer
Interview with Kenneth L. Kehl, MD, MPH, author of Rates of Guideline-Concordant Surgery and Adjuvant Chemotherapy Among Patients With Early-Stage Lung Cancer in the US ALCHEMIST Study (Alliance A151216). Hosted by Jack West, MD. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - March 17, 2022 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Oncology : Chemoradiotherapy Plus Induction or Consolidation Chemotherapy for Locally Advanced Rectal Cancer
Interview with Emmanouil Fokas, MD, DPhil, author of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer: Long-term Results of the CAO/ARO/AIO-12 Randomized Clinical Trial. Hosted by Jack West, MD. (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - November 18, 2021 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
Which method of determining MGMT promoter methylation best predicts survival in people with glioblastoma treated with temozolomide?
In March 2021, the Cochrane Neuro-Oncology Group published a series of eight new systematic reviews on priority topics for the brain tumour community. These were selected from the most important unanswered questions identified by patients, the public and practitioners. In this podcast, Kathreena Kurian from the University of Bristol in the UK tells us about one of the reviews, which looked at the evidence on tests that might help to predict survival in patients who have received chemotherapy for glioblastoma. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - May 27, 2021 Category: General Medicine Authors: Cochrane Source Type: podcasts
JAMA Surgery : Perioperative Systemic Therapy vs Surgery and HIPEC Alone for Colorectal Peritoneal Metastases
Interview with Ignace H. de Hingh, and Koen P Rovers, authors of Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases: A Phase 2 Randomized Clinical Trial (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - May 19, 2021 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
Prevention of blood clots in non-hospitalised cancer patients receiving chemotherapy
Alongside the hundreds of Cochrane Reviews of treatments for patients with cancer, there are many of ways to reduce the adverse effects of those treatments. In December 2020, we published the third update of one of these, looking at the effects of drugs to prevent venous thromboembolism in patients receiving chemotherapy. Marcello Di Nisio from the University "G. D'Annunzio" of Chieti-Pescara in Italy tells us about the latest findings in this podcast. (Source: Podcasts from The Cochrane Library)
Source: Podcasts from The Cochrane Library - April 23, 2021 Category: General Medicine Authors: Cochrane Source Type: podcasts
JAMA Oncology : Survival and Adjuvant Chemotherapy in Early-Stage NSCLC With vs Without Clinicopathologic Features
Interview with Daniel J Boffa, MD, author of Association of Survival With Adjuvant Chemotherapy Among Patients With Early-Stage Non–Small Cell Lung Cancer With vs Without High-Risk Clinicopathologic Features (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - September 17, 2020 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Oncology : Presence of ctDNA and CTCs After Chemotherapy and Recurrence of Triple-Negative Breast Cancer
Interview with Bryan P. Schneider, MD, and Milan Radovich, PhD, authors of Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer: Preplanned Secondary Analysis of the BRE12-158 Randomized Clinical Trial (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - July 9, 2020 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
JAMA Oncology : Durvalumab With or Without Tremelimumab vs Standard Chemotherapy for Metastatic NSCLC
Interview with Naiyer A. Rizvi, MD, author of Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non–Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial (Source: JAMA Specialty Journals Author Interviews)
Source: JAMA Specialty Journals Author Interviews - April 9, 2020 Category: General Medicine Authors: The JAMA Network Source Type: podcasts
