Methotrexate in RA: Can Response Be Predicted?
(MedPage Today) -- Yes, using easily available clinical and psychological factors, say researchers (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 20, 2018 Category: Primary Care Source Type: news

Meds Improve Cardiovascular Risk in RA
(MedPage Today) -- Benefits seen for hydroxychloroquine, methotrexate, and tocilizumab (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - June 15, 2018 Category: Cardiology Source Type: news

CleanCision Wins Readers ’ Choice Award in MDEA Competition
There was much pomp and circumstance at the Medical Design Excellence Awards Tuesday as the best technologies were honored at the Jacob K. Javits Convention Center in New York. For one technology, however, it was a strong call of validation. CleanCision, earned the overall Reader’s Choice Award, which spans all categories in the competition. The active cleansing technology also earned the 2018 Medical Device Excellence Award Bronze Medal in the ER and OR Tools Category. CleanCision was developed by San Carlos, CA-based Prescient Medical. “We’re thrilled and we’re honored for validation of what we&rs...
Source: MDDI - June 13, 2018 Category: Medical Devices Authors: Omar Ford Tags: Design Source Type: news

Safe Stopping of Tocilizumab in RA: MTX Helps Safe Stopping of Tocilizumab in RA: MTX Helps
Patients with rheumatoid arthritis who achieve 6 months of remission or low disease activity by taking methotrexate plus tocilizumab can usually stop tocilizumab; restarting is effective if flares occur.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 13, 2018 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Methotrexate Spares Steroids in Asthmatics
Title: Methotrexate Spares Steroids in AsthmaticsCategory: Doctor's& Expert's views on SymptomsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 6/13/2018 2:55:04 PM (Source: MedicineNet Asthma General)
Source: MedicineNet Asthma General - June 13, 2018 Category: Respiratory Medicine Source Type: news

Effect of Filgotinib With and Without Methotrexate in RA Effect of Filgotinib With and Without Methotrexate in RA
Filgotinib alone or as an addition to methotrexate may help rheumatoid arthritis patients realize improvements in patient-reported outcomes.Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 6, 2018 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

' Best Survival Data Ever' in Young T-Cell Leukemia Patients'Best Survival Data Ever' in Young T-Cell Leukemia Patients
Moving nelarabine to the front line and combining it with methotrexate improved 4-year disease-free survival in young patients with T-cell acute lymphoblastic leukemia.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 22, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

RA Therapy: After Methotrexate, Then What?
(MedPage Today) -- Strong preference for anti-TNF therapy despite emerging data (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - May 9, 2018 Category: Rheumatology Source Type: news

4 Trends Advancing Medtech
For the past 20 years, the Medical Design Excellence Awards have celebrated medical products that improve the quality and accessibility of healthcare. Our finalists this year carry on this tradition, while also keeping in step with today’s high-tech digital and consumer trends. With the help of our esteemed jurors, we have identified four key trends in this year’s group of finalists: risk reduction; faster, more-efficient healthcare delivery; the influence of the Internet of Things; and the consumerization of healthcare. We’ve been tracking a few of these trends in past awards programs, so they’re n...
Source: MDDI - April 27, 2018 Category: Medical Devices Authors: Daphne Allen Tags: MD & M East (New York) Design Source Type: news

Methotrexate Sodium Injection (Updated - Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 13, 2018 Category: Drugs & Pharmacology Source Type: news

Risk of Methotrexate Dosing Errors Prompts EMA Review Risk of Methotrexate Dosing Errors Prompts EMA Review
A recent routine assessment found that serious adverse events related to overdose, including fatalities, are still occurring, despite measures already in place to reduce dosing errors.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 13, 2018 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

Uveitis in JIA: Screen All, Treat Early (CME/CE)
(MedPage Today) -- Start with topical steroids, but methotrexate or biologics may be needed (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - April 4, 2018 Category: Pediatrics Source Type: news

Otrexup (Methotrexate Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 29, 2018 Category: Drugs & Pharmacology Source Type: news

2 Weeks Off Methotrexate OK for Flu Vaccine
(MedPage Today) -- Immunogenicity improved with no increase in RA disease activity (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 27, 2018 Category: Infectious Diseases Source Type: news

SetPoint Medical launches arthritis neurostim study
SetPoint Medical said today it launched the pilot trial of its neurostimulation device, looking to explore the system’s ability to to treat patients with drug refractory rheumatoid arthritis. The device is designed to be surgically placed on the vagus nerve to activate the body’s natural inflammatory reflex, the Valencia, Calif.-based company said. “Despite the effectiveness of biologic and targeted agents for the treatment of rheumatoid arthritis, many patients either do not respond, lose therapeutic response or are intolerant to these agents. There remains a real need to develop alternative therapeutic ...
Source: Mass Device - March 26, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Neuromodulation/Neurostimulation SetPoint Medical Source Type: news

Xatmep (Methotrexate Oral Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 26, 2018 Category: Drugs & Pharmacology Source Type: news

JIA Flares Fewer with Longer Inactive Disease
(MedPage Today) -- Study can inform decision-making on stopping methotrexate (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - February 21, 2018 Category: Pediatrics Source Type: news

Etanercept Biosimilar Is Effective, Well-tolerated for Rheumatoid Arthritis Etanercept Biosimilar Is Effective, Well-tolerated for Rheumatoid Arthritis
The biosimilar LBEC0101 is equivalent to etanercept (Enbrel) in treating patients with rheumatoid arthritis (RA) who respond inadequately to methotrexate, according to researchers from Korea and Japan.Reuters Health Information (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - February 20, 2018 Category: Orthopaedics Tags: Rheumatology News Source Type: news

Methotrexate May Help in Chronic Viral Arthritis (CME/CE)
(MedPage Today) -- Some benefits seen after chikungunya virus infection (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 26, 2018 Category: Infectious Diseases Source Type: news

Methotrexate Injection (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - January 25, 2018 Category: Drugs & Pharmacology Source Type: news

6,000-year-old track record for healing leaky gut
When I was traveling in India, I had the privilege of studying Ayurvedic medicine with traditional Master Healers. Surrounded by lakes, oceans and mountains, Kerala, India, is the birthplace of Ayurveda medicine. My plane landed in Mumbai. From there, I made the 800-mile trip to Kerala down on the southwestern-most tip of the Indian peninsula. With origins dating back 6,000 years, Kerala is the birthplace of Ayurvedic medicine. I spent a lot of time at the AyurMana or “ancient healing house.” This is the oldest existing school of Ayurvedic medicine in the world. It was there that I observed how quickly...
Source: Al Sears, MD Natural Remedies - January 17, 2018 Category: Complementary Medicine Authors: Cathy Card Tags: Health Natural Cures anxiety arthritis Cancer celiac disease chronic fatigue depression diabetes digestive issues fibromyalgia leaky gut multiple sclerosis schizophrenia Source Type: news

High-Dose vs Low-Dose Methotrexate in Patients With RA High-Dose vs Low-Dose Methotrexate in Patients With RA
Could higher doses of methotrexate offer additional benefits to patients with early rheumatoid arthritis?Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 9, 2018 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Low-dose Methotrexate: Determinants for Adverse Events Low-dose Methotrexate: Determinants for Adverse Events
What are the relative risks of adverse events in patients exposed to low-dose methotrexate vs. placebo, and what factors might predispose patients to these events?The British Journal of Dermatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 26, 2017 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

FDA OKs Tofacitinib (Xeljanz) for Active Psoriatic Arthritis FDA OKs Tofacitinib (Xeljanz) for Active Psoriatic Arthritis
The JAK inhibitor is indicated for patients who have failed to respond adequately or are intolerant to methotrexate or other disease-modifying antirheumatic drugs.FDA Approvals (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 18, 2017 Category: Allergy & Immunology Tags: Rheumatology News Alert Source Type: news

MTX Doubles Hepatotoxicity Risk in Psoriasis Patients
(MedPage Today) -- But methotrexate does not increase risk of liver disease in patients with rheumatoid arthritis (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 25, 2017 Category: Gastroenterology Source Type: news

Break From Methotrexate Boosts Flu Shot Efficacy in RA
With a drug holiday, patients with rheumatoid arthritis could improve their response to influenza vaccinations without increasing disease activity. (Source: CancerNetwork)
Source: CancerNetwork - November 14, 2017 Category: Cancer & Oncology Authors: Mariah Zebrowski Leach, JD, MS Tags: Rheumatoid Arthritis Source Type: news

Break From Methotrexate Boosts Flu Shot Efficacy in RA
With a drug holiday, patients with rheumatoid arthritis could improve their response to influenza vaccinations without increasing disease activity. (Source: ConsultantLive)
Source: ConsultantLive - November 14, 2017 Category: Internal Medicine Authors: Mariah Zebrowski Leach, JD, MS Tags: Rheumatoid Arthritis Source Type: news

Baricitinib Eases Rheumatoid Arthritis Pain Baricitinib Eases Rheumatoid Arthritis Pain
The JAK inhibitor reduced pain in rheumatoid arthritis patients refractory to methotrexate more than a TNF inhibitor, a new analysis of RA-BEAM data shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 8, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Stop Methotrexate in RA Patients for 2 Weeks After Flu Shot Stop Methotrexate in RA Patients for 2 Weeks After Flu Shot
A temporary suspension of methotrexate boosts the immune response to flu vaccination with no increase in rheumatoid arthritis (RA) disease activity, a randomized clinical trial shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 5, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Methotrexate Sodium Injection (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 12, 2017 Category: Drugs & Pharmacology Source Type: news

Hurricane Damage in Puerto Rico Leads to Fears of Drug Shortages Nationwide
Two weeks after Hurricane Maria hit Puerto Rico, manufacturers are scrambling to get their plants back on line and avoid production problems. (Source: NYT Health)
Source: NYT Health - October 4, 2017 Category: Consumer Health News Authors: KATIE THOMAS and SHEILA KAPLAN Tags: Drugs (Pharmaceuticals) Medical Devices Hurricane Maria (2017) Factories and Manufacturing Methotrexate (Drug) Power Failures and Blackouts Labor and Jobs Food and Drug Administration Health and Human Services Department American Society Source Type: news

RA Outcomes with Tocilizumab Surpass Those of Adalimumab, Methotrexate (CME/CE)
(MedPage Today) -- Benefits reflected in both physical and mental scores (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - September 25, 2017 Category: Rheumatology Source Type: news

RA Patient Outcomes with Baricitinib Beat Methotrexate (CME/CE)
(MedPage Today) -- Benefits seen for physical function, fatigue, and quality of life (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - September 21, 2017 Category: Geriatrics Source Type: news

Drug Aimed at Inflammation May Lower Risk of Heart Disease and Cancer
A milestone finding for researchers, the connection of inflammatory responses to such illnesses could open the door to new treatments. (Source: NYT Health)
Source: NYT Health - August 27, 2017 Category: Consumer Health News Authors: DENISE GRADY Tags: Brigham and Women's Hospital Lancet, The (Journal) Heart Lung Cancer Smoking and Tobacco Cholesterol Research Preventive Medicine Stroke Immune System Statins (Cholesterol-Lowering Drugs) Clinical Trials Methotrexate (Drug) Ridke Source Type: news

Studies: Biologic Proves Worth as Monotherapy in RA (CME/CE)
(MedPage Today) -- A replacement for methotrexate in some patients? (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - August 14, 2017 Category: Geriatrics Source Type: news

Arthritis warning: THIS common medication could be linked to deadly liver failure
ARTHRITIS causes symptoms including painful joints and stiffness. One type, rheumatoid arthritis, is often treated with medications that reduce discomfort - but the side effects of the drug methotrexate, can include liver failure. (Source: Daily Express - Health)
Source: Daily Express - Health - August 10, 2017 Category: Consumer Health News Source Type: news

New research shows drug used for arthritis can treat blood cancer
A new study funded by the UK Medical Research Council (MRC) has revealed that the arthritis drug methotrexate (MTX) can be used to treat patients with a type of blood cancer, polycythemia vera (PV). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 6, 2017 Category: Pharmaceuticals Source Type: news

MTX-induced Hypersensitivity Pneumonitis After 30 Years of Use MTX-induced Hypersensitivity Pneumonitis After 30 Years of Use
Methotrexate pneumonitis is not uncommon, but most frequently occurs within the first year of treatment. Could this patient's hypersensitivity pneumonitis be due to her 30 years on MTX?Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 31, 2017 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Evaluation of toxicity after acute accidental methotrexate ingestions in children under 6 years old: a 16-year multi-center review - Hays H, Beuhler MC, Spiller HA, Weber J, Mowry JB, Ryan ML, Spiller NE, Webb A.
CONTEXT: There is little data on the frequency of adverse events following acute methotrexate ingestions in pediatric patients. Likewise, recommendations for observation length, site and management strategies in this population are not well established. Th... (Source: SafetyLit)
Source: SafetyLit - July 25, 2017 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Can Methotrexate Cause Growths on Your Wrist?
Title: Can Methotrexate Cause Growths on Your Wrist?Category: Doctor's& Expert's views on SymptomsCreated: 7/21/2017 12:00:00 AMLast Editorial Review: 7/21/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 21, 2017 Category: Rheumatology Source Type: news

Nausea Common with Methotrexate in JIA (CME/CE)
(MedPage Today) -- Mitigating strategies include folate supplementation, anti-emetics (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - July 1, 2017 Category: Consumer Health News Source Type: news

Filgotinib Combined With MTX in Patients With Active RA Filgotinib Combined With MTX in Patients With Active RA
The addition of filgotinib may be an effective option for patients with active rheumatoid arthritis who did not sufficiently respond to methotrexate alone.Annals of the Rheumatic Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 21, 2017 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Fish as Medicine for Rheumatoid Arthritis
Eating fish may help reduce the joint pain and swelling of rheumatoid arthritis, a new study has found. (Source: NYT Health)
Source: NYT Health - June 21, 2017 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Fish and Other Marine Life Rheumatoid Arthritis Joints (Body Part) Methotrexate (Drug) Source Type: news

Tocilizumab Triumphs in Methotrexate Combo for RA Tocilizumab Triumphs in Methotrexate Combo for RA
It is not always clear which biologic to add to methotrexate for rheumatoid arthritis, but a new comparison between tocilizumab and a number of TNF inhibitors has some suggestions.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 20, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Rasuvo (Methotrexate Non-pyrogenic Solution for a Single Subcutaneous Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 31, 2017 Category: Drugs & Pharmacology Source Type: news

Moderate Alcohol Intake OK for RA Patients on Methotrexate
(MedPage Today) -- Patients on higher doses of meds may still need to abstain (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 30, 2017 Category: Primary Care Source Type: news

Triple Therapy More Cost-Effective Than MTX + Biologic in RA Triple Therapy More Cost-Effective Than MTX + Biologic in RA
Switching patients with MTX-resistant RA to triple-drug therapy (methotrexate, hydroxychloroquine, sulfasalazine) was recommended before changing to more expensive biologic therapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 30, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

In Rheumatoid Arthritis, Adding a Biologic Agent Before Trying Triple Therapy Likely Not Cost-Effective (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH For patients with active rheumatoid arthritis despite methotrexate therapy, adding a biologic agent (e.g., etanercept) before trying triple therapy would lead to substantial cost increases without much … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 30, 2017 Category: Primary Care Source Type: news

Biologics before triple therapy not cost effective for rheumatoid arthritis
(American College of Physicians) Stepping up to biologic therapy when methotrexate monotherapy fails offers minimal incremental benefit over using a combination of drugs known as triple therapy, yet incurs large costs for treating rheumatoid arthritis (RA). Results of a comprehensive cost-effectiveness analysis suggest that patients who have RA and no contraindications to triple therapy should use it prior to a biologic as the next regimen. The study is published in Annals of Internal Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 29, 2017 Category: International Medicine & Public Health Source Type: news

FDA Approves Sarilumab for Adults With Rheumatoid Arthritis FDA Approves Sarilumab for Adults With Rheumatoid Arthritis
The drug will be marketed in self-injectible prefilled syringes and pens to be used once every 2 weeks. It offers an alternative to drugs such as methotrexate.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 23, 2017 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news