TNF Inhibitor Plus Methotrexate Surpassed Monotherapy in PsA TNF Inhibitor Plus Methotrexate Surpassed Monotherapy in PsA
The addition of a TNF inhibitor to the treatment regimen of patients with psoriatic arthritis (PsA) improves the achievement of minimal disease activity, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 10, 2020 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Janssen Announces Submission of Two Applications to U.S. FDA Seeking Approval of SIMPONI ARIA ® (golimumab) for the Treatment of Polyarticular Juvenile Idiopathic Arthritis and Juvenile Psoriatic Arthritis
HORSHAM, PA, April 24, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of two supplemental Biologics License Applications (sBLA) to the U.S. Food and Drug Administration (FDA) seeking approval of SIMPONI ARIA® (golimumab) for the treatment of polyarticular juvenile idiopathic arthritis (pJIA) and juvenile psoriatic arthritis (jPsA), in patients two years of age and older in combination with methotrexate. If approved for these indications, SIMPONI ARIA would be the first anti-tumor necrosis factor (TNF)-alpha biologic agent administered by intravenous infusion available...
Source: Johnson and Johnson - April 24, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
IBD and COVID-19: Hold Certain Meds, AGA Advises
Patients with inflammatory bowel disease (IBD) who develop COVID-19 should stop taking thiopurines, methotrexate, tofacitinib, and biological therapies during the viral illness, according to the AGA. (Source: WebMD Health)
Source: WebMD Health - April 14, 2020 Category: Consumer Health News Source Type: news
Toxicity Due to Combination of Leflunomide and Methotrexate: Toxicity Due to Combination of Leflunomide and Methotrexate:
Therapy with methotrexate and leflunomide in a patient with active rheumatoid arthritis produced an unusual combination of drug-induced thrombotic microangiopathy and liver injury.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 14, 2020 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
Methotrexate Treatment of Chronic Chikungunya Arthritis Methotrexate Treatment of Chronic Chikungunya Arthritis
Is methotrexate a safe and effective therapeutic option for chikungunya-related chronic arthritis? The authors report their experience with this treatment.Journal of Clinical Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 14, 2020 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news
IBD and COVID-19: Hold Certain Meds, AGA Advises IBD and COVID-19: Hold Certain Meds, AGA Advises
Patients with inflammatory bowel disease (IBD) who develop COVID-19 should stop taking thiopurines, methotrexate, tofacitinib, and biological therapies during the viral illness, according to the AGA.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - April 14, 2020 Category: Gastroenterology Tags: Gastroenterology News Source Type: news
Methotrexate vs curettage for low-risk gestational trophoblastic neoplasia
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - March 31, 2020 Category: Drugs & Pharmacology Source Type: news
Roche initiates Phase III clinical trial of Actemra/RoActemra in hospitalised patients with severe COVID-19 pneumonia
Basel, 19 March 2020- Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced we are working with the Food& Drug Administration (FDA) to initiate a randomised, double-blind, placebo-controlled Phase III clinical trial in collaboration with the Biomedical Advanced Research and Development Authority (BARDA), a part of the US Health and Human Services Office of the Assistant Secretary for Preparedness and Response (ASPR), to evaluate the safety and efficacy of Actemra ®/RoActemra® (tocilizumab) plus standard of care in hospitalised adult patients with severe COVID-19 pneumonia compared to placebo plus standard of care. Th...
Source: Roche Media News - March 19, 2020 Category: Pharmaceuticals Source Type: news
Brief Update on Dermatologic Uses of Methotrexate Brief Update on Dermatologic Uses of Methotrexate
This review explores established and emerging clinical indications for methotrexate in dermatological conditions, including psoriasis, blistering diseases, chronic urticaria, slceroderma, and more.Skin Therapy Letter (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 24, 2020 Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news
Study Probes Side Effects of Methotrexate, Used for Psoriasis, Rheumatoid Arthritis
Title: Study Probes Side Effects of Methotrexate, Used for Psoriasis, Rheumatoid ArthritisCategory: Health NewsCreated: 2/18/2020 12:00:00 AMLast Editorial Review: 2/19/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - February 19, 2020 Category: Rheumatology Source Type: news
Risk for Adverse Events Up With Low-Dose Methotrexate
TUESDAY, Feb. 18, 2020 -- Use of low-dose methotrexate (LD-MTX) is associated with increased risks for adverse events (AEs), including skin cancer, and gastrointestinal, pulmonary, infectious, and hematologic AEs, according to research published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 18, 2020 Category: Pharmaceuticals Source Type: news
Study Probes Side Effects of Long-Used Methotrexate
People who took methotrexate had small-to-moderate increases in risks for skin cancer, infections, and gastrointestinal, lung and blood problems, according to the study published Feb. 17 in the Annals of Internal Medicine. (Source: WebMD Health)
Source: WebMD Health - February 18, 2020 Category: Consumer Health News Source Type: news
Study Probes Side Effects of Methotrexate, Used for Psoriasis, Rheumatoid Arthritis
TUESDAY, Feb. 18, 2020 -- Many Americans battling autoimmune illnesses such as rheumatoid arthritis or psoriasis turn to a long-used drug, methotrexate, for relief.
But until now there ' s been little comprehensive research on side effects tied to... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 18, 2020 Category: General Medicine Source Type: news
Biologics Tied to Greater Reduction in Pediatric Psoriasis
MONDAY, Feb. 10, 2020 -- Biologics seem to be associated with greater reduction in psoriasis severity scores and higher drug survival rates than methotrexate in pediatric patients treated in a real-world setting, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 10, 2020 Category: Pharmaceuticals Source Type: news
Reasons for Methotrexate Non-Adherence in Patients With RA Reasons for Methotrexate Non-Adherence in Patients With RA
Why might certain rheumatoid arthritis patients choose not to adhere to methotrexate therapy? Could certain factors predict non-adherence?Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 24, 2020 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news
