Metronomic Chemotherapy in a Real-world Population of Advanced Breast Cancer Patients
Conditions: Breast Cancer Interventions: Drug: cyclophosphamide , methotrexate , vinorelbine ,capecitabine Sponsors: Sun Yat-sen University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
The Comparison the CMV Infection and Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation Between Standard Regimen, Methotrexate Plus Cyclosporin A, and Post-transplant Cyclophosphamide-based Regimen
Conditions: CMV Infection or Reactivation After Allogenic HSCT Sponsors: Siriraj Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
Use of Letrozole for Ectopic Pregnancy
Conditions: Ectopic Pregnancy Interventions: Drug: Letrozole tablets; Drug: Methotrexate Sodium Sponsors: Hospital de Clinicas de Porto Alegre Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Ma-Spore ALL 2020 Study
Conditions: B Lymphoblastic Leukemia Interventions: Drug: Prednisolone; Drug: Dexamethasone; Drug: Vincristine; Drug: Methotrexate; Drug: L-Asparaginase; Drug: Pegylated asparaginase; Drug: Erwinase; Drug: Dasatinib; Drug: Imatinib; Drug: Cyclophosphamide; Drug: Cytarabine; Drug: Mercaptopurine; Drug: Thioguanine; Drug: Rituximab; Drug: Doxorubicin; Drug: Fludarabine Sponsors: National University Hospital, Singapore Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 28, 2024 Category: Research Source Type: clinical trials
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
Conditions: Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia Interventions: Drug: Asparaginase Erwinia chrysanthemi; Procedure: Biospecimen Collection; Biological: Blinatumomab; Procedure: Bone Marrow Aspiration; Drug: Calaspargase Pegol; Procedure: Computed Tomography; Drug: Cyclophosphamide; Drug: Cytarabine; Drug: Daunorubicin; Drug: Dexamethasone; Drug: Doxorubicin; Procedure: Echocardiography; Procedure: FDG-Positron Emission Tomography; Drug: Leucovorin; Procedure: Lumbar Puncture; Procedure: Magnetic Resonance Imaging; Drug: Mercaptopurine; Drug: Methotrexate; Procedure: Multigated Acquisition Sca...
Source: ClinicalTrials.gov - March 19, 2024 Category: Research Source Type: clinical trials
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Conditions: GVHD,Acute; Acute Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders Interventions: Drug: ATG Combined with Tacrolimus and Mini Methotrexate Sponsors: University of Alabama at Birmingham Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials
GAMEC-II, Risk-adapted Protocol for Relapsed Germ Cell Tumours (GCT)
Conditions: Testicular Neoplasms Interventions: Drug: Pegfilgrastim; Drug: Dactinomycin; Drug: Methotrexate; Drug: Etoposide; Drug: Cisplatin; Drug: Epirubicin Sponsors: Queen Mary University of London Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
The efficacy and safety of deucravacitinib compared to methotrexate, in patients with vulvar lichen planus who have failed topical therapy with potent corticosteroids: a study protocol for a single-centre double-blinded randomised controlled trial
DiscussionHigh-quality evidence guiding the management of women with VLP is lacking. Once completed, this will be the first double-blinded RCT to compare systemic treatments in VLP. The results of this study will provide valuable, high-quality data to guide second-line therapy options for VLP that is recalcitrant to potent topical corticosteroids.Trial registrationAustralian New Zealand Clinical Trials Registry ACTRN12623000682640. Registered on 26 June 2023. (Source: Trials)
Source: Trials - March 12, 2024 Category: Research Source Type: clinical trials
Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis
Conditions: Rheumatoid Arthritis Interventions: Drug: Methotrexate Combined With Tofacitinib; Drug: Methotrexate Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Treatment of Ectopic Pregnancy by Low Dose of Methotrexate
Conditions: Ectopic Pregnancy Interventions: Drug: Methotrexate Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.
Conditions: Gout Interventions: Drug: SIBP-R002; Drug: SIBP-R002; Drug: SIBP-R002; Drug: Methotrexate Sponsors: Shanghai Institute Of Biological Products; First Affiliated Hospital Bengbu Medical College; The First Affiliated Hospital of Henan University of Science and Technology; Chengdu Fifth People ' s Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma
Conditions: Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Mixed Phenotype Acute Leukemia Interventions: Drug: Dexamethasone; Drug: Vincristine; Drug: Daunorubicin; Drug: Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine); Drug: Methotrexate; Drug: Cytarabine Sponsors: St. Jude Children ' s Research Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
" Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy "
Conditions: Proliferative Vitreoretinopathy Interventions: Drug: Methotrexate Sponsors: University of Health Sciences Lahore Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
A Post-trial Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate Treatment in Adults With Erosive Hand OA.
Conditions: Hand Osteoarthritis; Erosive Osteoarthritis Interventions: Drug: Methotrexate; Other: No treatment Sponsors: Diakonhjemmet Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases
Conditions: Rheumatoid Arthritis; Psoriatic Arthritis; Psoriasis Interventions: Drug: Silymarin; Drug: Placebo Sponsors: Phramongkutklao College of Medicine and Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
