The only kids who need vitamins (spoiler alert: there aren ’t many)
As a pediatrician, I get a lot of questions whether their children should take a multivitamin or other vitamin supplement. Parents think they will make their children healthier — and some think they will make them eat more (they don’t, sorry). Since our bodies need different vitamins to be healthy, they ask, Should I give my child a multivitamin? Not necessarily, actually. It turns out that most children don’t need them, making them an expensive waste of money. They can also be dangerous if children take too many, something that is very possible given that most chewable multivitamins for children taste like candy. An...
Source: Thrive, Children's Hospital Boston - March 23, 2017 Category: Pediatrics Authors: Claire McCarthy Tags: Ask the Expert Health & Wellness Claire McCarthy vitamins Source Type: news

Masonic Charitable Foundation awards grant to microbiome research
The Masonic Charitable Foundation has awarded£90,000 over three years to Arthritis Research UK, to support research into the role of the microbiome in rheumatoid arthritis.The grant will support Dr Frances Williams at King’s College London, to explore whether the mix of bacteria in and on our bodies (known as the microbiome) drives rheumatoid arthritis, or whether changes in these bacteria are a consequence of the disease or the drugs used to treat it.The researchAround 400,000 people in the UK have rheumatoid arthritis but the best drugs available do not work for everyone. We know that the microbiome in people...
Source: Arthritis Research UK - February 27, 2017 Category: Rheumatology Source Type: news

Baricitinib Might Offer Oral Alternative to Adalimumab in RA Baricitinib Might Offer Oral Alternative to Adalimumab in RA
A phase 3 trial in patients with rheumatoid arthritis who did not respond to methotrexate showed that the addition of baricitinib produced significant clinical improvements.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 22, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Arthritis Drugs Get Nod From EMA's CHMP Arthritis Drugs Get Nod From EMA's CHMP
Tofacitinib citrate (Xeljanz), two adalimumab (Humira) biosimilars, and one methotrexate hybrid get thumbs up from EMA committee.International Approvals (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - January 27, 2017 Category: Dermatology Tags: Rheumatology News Alert Source Type: news

Psoriasis and Arthritis Drugs Get Nod From EMA's CHMP Psoriasis and Arthritis Drugs Get Nod From EMA's CHMP
Tofacitinib citrate (Xeljanz), two adalimumab (Humira) biosimilars, and one methotrexate hybrid get thumbs up from EMA committee.International Approvals (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - January 27, 2017 Category: Drugs & Pharmacology Tags: Rheumatology News Alert Source Type: news

What can clinicians learn from therapeutic studies about the treatment of acute oral methotrexate poisoning? - Chan BS, Dawson AH, Buckley NA.
CONTEXT: Methotrexate (MTX) is an anti-folate drug that has been utilized in both malignant and chronic inflammatory conditions. Doctors are often concerned with a potential adverse outcome when managing patients with acute oral MTX poisoning given its pot... (Source: SafetyLit)
Source: SafetyLit - January 21, 2017 Category: Global & Universal Tags: Poisoning Source Type: news

Study Questions High-Dose Methotrexate in Early RA (CME/CE)
But formulation (MedPage Today) -- oral vs subcutaneous -- may make a difference (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 3, 2017 Category: Primary Care Source Type: news

Rheumatrex (Methotrexate Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 3, 2017 Category: Drugs & Pharmacology Source Type: news

Subcutaneous Methotrexate Safe, Effective for Psoriasis Subcutaneous Methotrexate Safe, Effective for Psoriasis
Subcutaneous methotrexate with an intensified 52-week dosing schedule should be considered for patients with psoriasis because of its favorable risk-benefit profile.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 30, 2016 Category: Consumer Health News Tags: Dermatology News Source Type: news

Teenager's psoriasis is cured by a cancer drug methotrexate
Elizabeth Wigmore, 18, from South Wales, has suffered from psoriasis - which caused her intense pain and bleeding - for four years. She now takes methotrexate each week to keep her symptoms at bay. (Source: the Mail online | Health)
Source: the Mail online | Health - December 13, 2016 Category: Consumer Health News Source Type: news

‘Turbocharged artificial intelligence’ could personalize combination therapy in pediatric leukemia
In this study, patient records were obtained on the dosing of 6-mercaptopurine and methotrexate, as well as on the corresponding  absolute neutrophil count, or levels of a subset of white blood cells called neutrophils that are vital for staving off potentially life-threatening infections. These records showed multiple instances where conventional chemotherapy doses caused deviations from acceptable neutrophil levels. Using the personalized medicine technology, individualized three-dimensional maps were generated to determine the optimal 6-mercaptopurine/methotrexate drug ratios.The team members found that their technolog...
Source: UCLA Newsroom: Health Sciences - December 12, 2016 Category: Universities & Medical Training Source Type: news

Tocilizumab in RA With Inadequate Response to Methotrexate Tocilizumab in RA With Inadequate Response to Methotrexate
Does the addition of or switch to tocilizumab provide any additional benefits for rheumatoid arthritis patients who do not sufficiently respond to methotrexate alone?Annals of the Rheumatic Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 7, 2016 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Methotrexate Greatly Underprescribed for U.S. RA Patients (CME/CE)
(MedPage Today) -- The staple DMARD should be utilized longer, at higher doses, and via subcutaneous delivery, researchers say (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - December 2, 2016 Category: Geriatrics Source Type: news

Methotrexate ‘ Dramatically ’ Underused for RA Methotrexate ‘ Dramatically ’ Underused for RA
Methotrexate, the"anchor" drug for rheumatoid arthritis (RA), is"dramatically underutilized in clinical practice," researchers report.Reuters Health Information (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - December 1, 2016 Category: Orthopaedics Tags: Rheumatology News Source Type: news

A case of methotrexate intoxication in a patient with psoriasis who drank beetroot juice during methotrexate treatment - G önül M, Keseroglu H, Hacınecipoğlu F.
We report a 50-year-old woman being treated with methotrexate for psoriasis who developed methotrexate intoxication... (Source: SafetyLit)
Source: SafetyLit - November 25, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news