Exposure to Ambient Particulate Matter during Specific Gestational Periods Produces Adverse Obstetric Consequences in Mice

Conclusions:
Adverse PM2.5-induced outcomes such as PTB and LBW are dependent upon the periods of maternal exposure. The results of these experimental studies could contribute significantly to air pollution policy decisions in the future. https://doi.org/10.1289/EHP1029

Received: 26 August 2016
Revised: 12 December 2016
Accepted: 23 January 2017
Published: 27 July 2017
Address correspondence to J. Zelikoff, Department of Environmental Medicine, New York University School of Medicine, 57 Old Forge Rd., Tuxedo, NY 10987 USA. Telephone: [phone]. Email: [e-mail]
The authors declare they have no actual or potential competing financial interests.
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Introduction
In the United States, ∼11% of all pregnancies result in preterm birth (PTB; birth prior to 37 wk gestation) (March of Dimes 2014). Although the reasons for this outcome are varied, exposure of pregnant women to elevated levels of fine-sized ambient particulate matter (PM2.5) has been identified in numerous epidemiologic studies as a...

Source: EHP Research - July 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research