Breathing easier with a better tracheal stent
(University of Pittsburgh) New research led by the University of Pittsburgh is poised to drastically improve the use of tracheal stents for children with airway obstruction. Researchers demonstrate for the first time the successful use of a completely biodegradable magnesium-alloy tracheal stent that safely degrades and does not require removal. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 15, 2021 Category: International Medicine & Public Health Source Type: news
Mechanisms in the kidney that control magnesium and calcium levels discovered
(Massachusetts General Hospital) The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly absorb magnesium and calcium from urine in the kidney, leading to abnormally low magnesium and calcium blood levels, thereby triggering the parathyroid glands to secrete excess parathyroid hormone that in turn leads to metabolic bone disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 12, 2021 Category: Biology Source Type: news
Cipla recalls over 5.8 lakh packets of gastric ulcer treatment drug in US
The drug major is recalling esomeprazole magnesium for delayed-release oral suspension in unit dose packets in strengths 10 mg, 20 mg and 40 mg in the US market, the latest Enforcement Report by the USFDA said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 10, 2021 Category: Pharmaceuticals Source Type: news
High cholesterol: Magnesium or green tea extract supplements could help lower your levels
HIGH cholesterol is an insidious condition whereby the sufferer remains completely oblivious to the dangers that lies deep within. Left untreated though and serious health risks will ensue. By taking either magnesium or green tea extract supplements your levels can be greatly lowered. (Source: Daily Express - Health)
Source: Daily Express - Health - December 29, 2020 Category: Consumer Health News Source Type: news
Incorporating magnesium-rich foods into your diet helps reduce insulin resistance even if you don’t have diabetes
(Natural News) Magnesium is an essential nutrient that contributes to overall health. It plays a key role in several bodily processes, including the regulation of muscle and nerve function, blood sugar and blood pressure control, protein synthesis and the formation of strong bones. Multiple studies have found that magnesium helps reduce insulin resistance — a major factor in... (Source: NaturalNews.com)
Source: NaturalNews.com - December 22, 2020 Category: Consumer Health News Source Type: news
The latest magnesium studies pave the way for new biomedical materials
(The Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences) Materials used in biomedicine must be characterized by controlled biodegradability, sufficient strength and total absence of toxicity to the human body. The search for such materials is, therefore, not a simple task. In this context, scientists have been interested in magnesium for a long time. Recently, using such techniques as positron annihilation spectroscopy, the researchers were able to demonstrate that magnesium subjected to surface mechanical attrition treatment obtains the properties necessary for a biocompatible material. (Source...
Source: EurekAlert! - Biology - December 17, 2020 Category: Biology Source Type: news
A randomized cohort study of the efficacy of PO magnesium in the treatment of acute concussions in adolescents - Standiford L, O'Daniel M, Hysell M, Trigger C.
INTRODUCTION/STUDY OBJECTIVE: Concussions are becoming a growing concern in society today with one out of every five adolescents being affected. This accounts for 1.6 to 3.8 million emergency department visits annually. The current standard of care involve... (Source: SafetyLit)
Source: SafetyLit - November 30, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
An extremely metal-deficient globular cluster in the Andromeda Galaxy
We report a massive GC in the Andromeda Galaxy (M31), RBC EXT8, that is extremely depleted in heavy elements. Its iron abundance is about 1/800 that of the Sun and about one-third that of the most iron-poor GCs previously known. It is also strongly depleted in magnesium. These measurements challenge the notion of a metallicity floor for GCs and theoretical expectations that massive GCs could not have formed at such low metallicities. (Source: ScienceNOW)
Source: ScienceNOW - November 19, 2020 Category: Science Authors: Larsen, S. S., Romanowsky, A. J., Brodie, J. P., Wasserman, A. Tags: Astronomy reports Source Type: news
Sutab (Sodium Sulfate, Magnesium Sulfate, and Potassium Chloride Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 18, 2020 Category: Drugs & Pharmacology Source Type: news
FDA Approves Sutab (sodium sulfate, magnesium sulfate, and potassium chloride) Tablets for Colonoscopy Preparation
BRAINTREE, Mass., Nov. 10, 2020 /PRNewswire/ -- Sebela Pharmaceuticals® today announces that the U.S. Food and Drug Administration (FDA) approved Sutab® (sodium sulfate, magnesium sulfate, and potassium chloride) tablets. Sutab, a... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - November 10, 2020 Category: Drugs & Pharmacology Source Type: news
Dietitian reveals the nutrient missing from your diet - and the ideal day on a plate to get more
Sydney dietitian Susie Burrell has revealed the importance of magnesium, the key role it plays in the body and how much you need every day. (Source: the Mail online | Health)
Source: the Mail online | Health - November 3, 2020 Category: Consumer Health News Source Type: news
Magnesium is a cheap and natural supplement proven to lower a high blood pressure reading
HIGH blood pressure is a precursor to heart disease so it is imperative to keep it in check. Simple lifestyle tweaks can lower a high reading, including taking a mineral supplement. (Source: Daily Express - Health)
Source: Daily Express - Health - October 22, 2020 Category: Consumer Health News Source Type: news
Review IDs Dietary Factors Linked to Lower CRC Incidence
WEDNESDAY, Sept. 30, 2020 -- Decreased colorectal cancer (CRC) incidence is seen in association with use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), magnesium, folate, and high consumption of fruits and vegetables, fiber, and dairy... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 30, 2020 Category: Pharmaceuticals Source Type: news
Talicia (Omeprazole Magnesium, Amoxicillin and Rifabutin Delayed-release Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 16, 2020 Category: Drugs & Pharmacology Source Type: news
Could magnesium pills be the secret to staying strong in later life?
A recently published study from the University of East Anglia, involving 441 people, found a direct link between physical strength in older people and the amount of magnesium in their muscle tissue. (Source: the Mail online | Health)
Source: the Mail online | Health - September 7, 2020 Category: Consumer Health News Source Type: news
Char application restores soil carbon and productivity
(American Society of Agronomy) After two years of char application, researchers find increased soil Carbon, magnesium, and sodium concentrations. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - August 27, 2020 Category: Biology Source Type: news
Featured Review: Interventions for acute severe asthma attacks in children: an overview of Cochrane Reviews
Interventions for acute severe asthma attacks in children: an overview of Cochrane ReviewsAsthma is a common childhood illness that is caused by narrowing of the small air passages in the lungs. This narrowing is due to swelling and inflammation and to muscles around the air passages becoming tighter. An acute asthma attack results in shortness of breath, cough, wheeze, and chest tightness.When children have an asthma attack, the standard treatment is to give steroids to reduce inflammation and swelling (usually given by mouth) and inhaled medications to relax the muscles in the air passages (called " bronchodilators ...
Source: Cochrane News and Events - August 6, 2020 Category: Information Technology Authors: Katie Abbotts Source Type: news
Xywav (Calcium, Magnesium, Potassium, and Sodium Oxybates Oral Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 3, 2020 Category: Drugs & Pharmacology Source Type: news
Xywav (Calcium, Magnesium, Potassium, and Sodium Oxybates Oral Solution) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 29, 2020 Category: Drugs & Pharmacology Source Type: news
Jazz Pharmaceuticals Announces U.S. FDA Approval of Xywav(TM) (calcium, magnesium, potassium, and sodium oxybates) Oral Solution for Cataplexy or Excessive Daytime Sleepiness Associated with Narcolepsy
Xywav is the first FDA approved new treatment option indicated for both cataplexy and excessive daytime sleepiness in people living with narcolepsy in more than 15 years Xywav contains 92 percent less sodium per nightly dose than sodium oxybate, a curre... Biopharmaceuticals, Neurology, FDA Jazz Pharmaceuticals, Xywav, Cataplexy, Narcolepsy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 22, 2020 Category: Pharmaceuticals Source Type: news
FDA Approves Xywav (calcium, magnesium, potassium, and sodium oxybates) Oral Solution for Cataplexy or Excessive Daytime Sleepiness Associated with Narcolepsy
DUBLIN, July 22, 2020 /PRNewswire/ -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that the U.S. Food and Drug Administration (FDA) approved Xywav™ (calcium, magnesium, potassium, and sodium oxybates)... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 22, 2020 Category: Drugs & Pharmacology Source Type: news
A dual antenatal therapy benefits extreme preterm babies better than either alone or none
(University of Alabama at Birmingham) Researchers, led by Samuel Gentle, MD, assistant professor of pediatrics in the University of Alabama at Birmingham School of Medicine, report that antenatal treatment with both magnesium sulfate and corticosteroids together yields an increased benefit for children born at 22 to 26 weeks of gestation, compared to no antenatal treatment or with either therapy alone. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2020 Category: International Medicine & Public Health Source Type: news
Day in, day out: Targeting the daily magnesium " rhythm " can optimize crop yield
(Okayama University) Many processes of photosynthesis, including the intake of magnesium, follow a pattern of variation over 24 hours. In a new study, scientists from Okayama University, Japan and Fujian A& F University, China, tested the effect of this variation on the efficiency of photosynthesis in rice plants. Their findings suggest potential candidates for modification for increasing the yield of rice crops, thereby offering a potential solution to the global food shortage. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 10, 2020 Category: Biology Source Type: news
Best supplements for the heart - the 3p a day capsules to lower your risk of heart attacks
SUPPLEMENTS could be used to improve the health of your heart, as well as to protect against heart attack symptoms and signs. Add these cheap magnesium capsules to your diet to lower your risk of high blood pressure. (Source: Daily Express - Health)
Source: Daily Express - Health - June 25, 2020 Category: Consumer Health News Source Type: news
Aluminum oxide crystal tested as a UV radiation sensor
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Doped with carbon and magnesium, the material becomes thermoluminescent in response to UV radiation. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 2, 2020 Category: Cancer & Oncology Source Type: news
U.S. FDA Approves New Pediatric Formulation of SIRTURO ® (bedaquiline) as Part of Combination Therapy to Treat Children with Pulmonary Multidrug-Resistant Tuberculosis
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received acceler...
Source: Johnson and Johnson - May 27, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
If you work out, you need magnesium: It promotes recovery after strenuous exercise
(Natural News) Magnesium is an essential nutrient that plays an important role in muscular health and recovery. After a grueling workout, you need to replenish your electrolytes and magnesium levels. Magnesium and muscle recovery In a study involving marathon runners, researchers discovered that magnesium was the most highly depleted electrolyte in the participants, with potassium a close second.... (Source: NaturalNews.com)
Source: NaturalNews.com - May 19, 2020 Category: Consumer Health News Source Type: news
Magnesium and osteoporosis: 10 Reasons why magnesium could prevent osteoporosis
(Natural News) Magnesium is an essential mineral that promotes overall well-being. Meeting your daily requirement of magnesium — by eating magnesium-rich foods or taking supplements — also helps keep your bones healthy and prevents the onset of osteoporosis. Research conducted in the U.S. and Europe has found that magnesium helps prevent osteoporosis in both men and... (Source: NaturalNews.com)
Source: NaturalNews.com - May 14, 2020 Category: Consumer Health News Source Type: news
Ronald Reagan ’s Secret Cancer Cure
There’s no faster way to purify your body of viruses, bacteria and fungi — and at the same time ramp up your immune system — than a 125-year-old “cure” banned by the FDA. I’m talking about ozone therapy — and it’s not just good for cleansing your body. You see, ozone — a special “energized” kind of oxygen — can help heal almost any condition. Despite being banned by the FDA back in the 1940s, after more than 60 years of successful use, ozone therapy has saved millions of lives in countries where it has become a commonplace medical treatment. In count...
Source: Al Sears, MD Natural Remedies - May 12, 2020 Category: Complementary Medicine Authors: Dr.A.Sears Tags: Health Source Type: news
Letting chickens get plenty of sunlight may help boost the vitamin D content of their eggs
(Natural News) Vitamin D is a nutrient needed by the body for the absorption of calcium, magnesium and phosphorus. It belongs to a family of cholesterol-derived compounds and has two major forms: vitamin D2, also known as ergocalciferol, and vitamin D3, also called cholecalciferol. Vitamin D is also known by many as the “sunshine vitamin” because it is produced... (Source: NaturalNews.com)
Source: NaturalNews.com - May 7, 2020 Category: Consumer Health News Source Type: news
Best supplements for the heart - the best capsule to protect against high blood pressure
SUPPLEMENTS could be used to improve the health of your heart, as well as to protect against high blood pressure symptoms and signs. Add these cheap magnesium capsules to your diet to lower your risk of heart attacks. (Source: Daily Express - Health)
Source: Daily Express - Health - April 19, 2020 Category: Consumer Health News Source Type: news
Best supplements for tiredness - the 3p a day capsules to prevent fatigue and boost energy
SUPPLEMENTS could be used to prevent tiredness and fatigue symptoms. Add these cheap capsules to your diet to avoid feeling sleepy or drowsy during the day, while also boosting your overall energy. Do you eat enough magnesium-rich foods? (Source: Daily Express - Health)
Source: Daily Express - Health - April 14, 2020 Category: Consumer Health News Source Type: news
Bupivacaine With/Without Magnesium Sulfate for Postop Analgesia Bupivacaine With/Without Magnesium Sulfate for Postop Analgesia
Does the addition of magnesium sulfate as an adjuvant of epidural bupivacaine improve postoperative analgesia over bupivacaine alone?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 13, 2020 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news
What Causes Tachycardia?
Discussion Tachycardia is a rapid heart rate that is above normal for age and level of exertion. Tachycardia is common, particularly sinus tachycardia due to normally encountered circumstances such as pain, fever or exercise. It is usually a normal physiologic process but sustained tachycardia often indicates a potentially abnormal underlying cause. Sinus tachycardia has a rapid heart rate with normal P waves and P-R intervals and variations from moment to moment and respiration. Generally it is not over 200 beats/minute. Vagal stimulation can slow the heart rate; this is a gradual slowing, not an abrupt slowing seen in ...
Source: PediatricEducation.org - March 23, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Magnesium protects against sepsis by blocking gasdermin D N-terminal-induced pyroptosis
Hypomagnesemia is a significant risk factor for critically ill patients to develop sepsis, a life-threatening disease with a mortality rate over 25%. Our clinic data analysis showed that hypomagnesemia is associated with a decreased monocyte count in septic patients. At the cellular level, we found that Mg2+ inhibits pyroptosis. Specifically, Mg2+ limits the oligomerization and membrane localization of gasdermin D N-terminal (GSDMD-NT) upon the activation of either the canonical or noncanonical pyroptotic pathway. Mechanistically, we demonstrated that Ca2+ influx is a prerequisite for the function of GSDMD-NT. Mg2+ blocks ...
Source: Current Awareness Service for Health (CASH) - March 13, 2020 Category: Consumer Health News Source Type: news
New research finds infant cereal consumption is associated with improved nutrient intake
(Pollock Communications) An investigation of infant feeding patterns found infants and toddlers consuming baby cereal, such as rice cereal, had higher intakes of key nutrients of concern, such as calcium, magnesium, iron, zinc and vitamin E. The study illustrates the importance of rice baby cereal in the diets of infants and toddlers in achieving proper nutrition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 10, 2020 Category: International Medicine & Public Health Source Type: news
What Are Some Risk Factors for Cerebral Palsy?
Discussion The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis
Mycobacterium tuberculosis has an unusual outer membrane that lacks canonical porin proteins for the transport of small solutes to the periplasm. We discovered that 3,3-bis-di(methylsulfonyl)propionamide (3bMP1) inhibits the growth of M. tuberculosis, and resistance to this compound is conferred by mutation within a member of the proline-proline-glutamate (PPE) family, PPE51. Deletion of PPE51 rendered M. tuberculosis cells unable to replicate on propionamide, glucose, or glycerol. Growth was restored upon loss of the mycobacterial cell wall component phthiocerol dimycocerosate. Mutants in other proline-glutamate (PE)/PPE ...
Source: ScienceNOW - March 4, 2020 Category: Science Authors: Wang, Q., Boshoff, H. I. M., Harrison, J. R., Ray, P. C., Green, S. R., Wyatt, P. G., Barry, C. E. Tags: Medicine, Diseases reports Source Type: news
The effect of magnesium chloride as an anti-icing agent on tire/road friction coefficient - Leggett TS, Brewer E.
This article reports on the findings of tests designed to measure the effectiveness of magnesium chloride (MgCL ₂) as an anti-icing agent on tire/road friction coefficient. Skid tests under various conditions are conducted using a 1996 Chevrolet Caprice a... (Source: SafetyLit)
Source: SafetyLit - February 18, 2020 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Dry reforming of methane by stable Ni-Mo nanocatalysts on single-crystalline MgO
Large-scale carbon fixation requires high-volume chemicals production from carbon dioxide. Dry reforming of methane could provide an economically feasible route if coke- and sintering-resistant catalysts were developed. Here, we report a molybdenum-doped nickel nanocatalyst that is stabilized at the edges of a single-crystalline magnesium oxide (MgO) support and show quantitative production of synthesis gas from dry reforming of methane. The catalyst runs more than 850 hours of continuous operation under 60 liters per unit mass of catalyst per hour reactive gas flow with no detectable coking. Synchrotron studies also show ...
Source: ScienceNOW - February 12, 2020 Category: Science Authors: Song, Y., Ozdemir, E., Ramesh, S., Adishev, A., Subramanian, S., Harale, A., Albuali, M., Fadhel, B. A., Jamal, A., Moon, D., Choi, S. H., Yavuz, C. T. Tags: Chemistry, Materials Science reports Source Type: news
Structural basis of second-generation HIV integrase inhibitor action and viral resistance
Although second-generation HIV integrase strand-transfer inhibitors (INSTIs) are prescribed throughout the world, the mechanistic basis for the superiority of these drugs is poorly understood. We used single-particle cryo–electron microscopy to visualize the mode of action of the advanced INSTIs dolutegravir and bictegravir at near-atomic resolution. Glutamine-148->histidine (Q148H) and glycine-140->serine (G140S) amino acid substitutions in integrase that result in clinical INSTI failure perturb optimal magnesium ion coordination in the enzyme active site. The expanded chemical scaffolds of second-generation c...
Source: ScienceNOW - February 12, 2020 Category: Science Authors: Cook, N. J., Li, W., Berta, D., Badaoui, M., Ballandras-Colas, A., Nans, A., Kotecha, A., Rosta, E., Engelman, A. N., Cherepanov, P. Tags: Biochemistry, Microbiology reports Source Type: news
Janssen to Highlight Depth of Solid Tumor Portfolio at ASCO GU
RARITAN, N.J., February 3, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today multiple data presentations from a robust solid tumor portfolio that will be featured at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco. Company-sponsored data presentations will include clinical results for ERLEADA® (apalutamide) and niraparib in prostate cancer; and BALVERSA™ (erdafitinib) in bladder cancer. “We are committed to improving outcomes in patients with prostate and bladder cancer where high unmet...
Source: Johnson and Johnson - February 3, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
Magnesium Disorders Up Hypocalcemia Risk After Thyroidectomy Magnesium Disorders Up Hypocalcemia Risk After Thyroidectomy
Hypocalcemia occurred in nearly 20% of patients following thyroidectomy in the large study, however, most cases resolved at 1 year.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - January 17, 2020 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
Magnesium Inversely Linked to Risk for Coronary Heart Disease
FRIDAY, Dec. 27, 2019 -- For postmenopausal women, dietary magnesium is inversely associated with fatal coronary heart disease (CHD), according to a study published online Dec. 12 in the Journal of Women's Health. Jason Li, D.O., from the Alpert... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 27, 2019 Category: Pharmaceuticals Source Type: news
Could higher magnesium intake reduce fatal coronary heart disease risk in women?
(Mary Ann Liebert, Inc./Genetic Engineering News) A new prospective study based on data from the Women's Health Initiative found a potential inverse association between dietary magnesium and fatal coronary heart disease in postmenopausal women. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 23, 2019 Category: International Medicine & Public Health Source Type: news
Magnetic measurements on micrometer-sized samples under high pressure using designed NV centers
We report a method for spatially resolved optical magnetometry based on imaging a layer of nitrogen-vacancy (NV) centers created at the surface of a diamond anvil. We illustrate the method using two sets of measurements realized at room temperature and low temperature, respectively: the pressure evolution of the magnetization of an iron bead up to 30 gigapascals showing the iron ferromagnetic collapse and the detection of the superconducting transition of magnesium dibromide at 7 gigapascals. (Source: ScienceNOW)
Source: ScienceNOW - December 11, 2019 Category: Science Authors: Lesik, M., Plisson, T., Toraille, L., Renaud, J., Occelli, F., Schmidt, M., Salord, O., Delobbe, A., Debuisschert, T., Rondin, L., Loubeyre, P., Roch, J.-F. Tags: Physics reports Source Type: news
Zydus Cadila files NDA for Saroglitazar Magnesium
NASH is a progressive disease of the liver and a significant unmet medical need. There are currently no treatments available for the treatment of NASH. aroglitazar Mg has previously demonstrated improvement in both liver enzymes along with favorable effects on lipid and glycemic indices in patients with nonalcoholic fatty liver disease in Phase II clinical trials. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 4, 2019 Category: Pharmaceuticals Source Type: news
Not getting enough magnesium? You might be at risk of heart disease, depression
(Natural News) Being deficient in nutrients comes with serious health risks. Having low levels of magnesium, for instance, can increase your risk of cardiovascular diseases and depression. In a study published in the journal Atherosclerosis, researchers found that people with low magnesium levels are at risk of developing peripheral artery disease (PAD). When the participants... (Source: NaturalNews.com)
Source: NaturalNews.com - November 27, 2019 Category: Consumer Health News Source Type: news
Host resistance factor SLC11A1 restricts Salmonella growth through magnesium deprivation
The pleiotropic host resistance factor SLC11A1 (NRAMP1) defends against diverse intracellular pathogens in mammals by yet-unknown mechanisms. We compared Salmonella infection of coisogenic mice with different SLC11A1 alleles. SLC11A1 reduced Salmonella replication and triggered up-regulation of uptake systems for divalent metal cations but no other stress responses. SLC11A1 modestly diminished iron availability and acutely restricted Salmonella access to magnesium. Growth of Salmonella cells in the presence of SLC11A1 was highly heterogeneous and inversely correlated with expression of the crucial magnesium transporter gen...
Source: ScienceNOW - November 20, 2019 Category: Science Authors: Cunrath, O., Bumann, D. Tags: Immunology, Microbiology reports Source Type: news