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Manganese-based MRI contrast agent may be safer alternative to gadolinium-based agents
(Massachusetts General Hospital) A team of Massachusetts General Hospital researchers has developed a manganese-based magnetic resonance imaging contrast agent, a potential alternative to gadolinium-based agents, which carry significant health risks for some patients (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 15, 2017 Category: International Medicine & Public Health Source Type: news

Washington University gets $3.7 million to study neurological disorders
Washington University has received $3.7 million in funding from the National Institutes of Health to study neurological disorders linked to manganese, an element found in smoke from steel production and coal fires. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 16, 2017 Category: American Health Authors: Angela Mueller Source Type: news

Medical News Today: Too much manganese may lower children's IQ
A study suggests that excessive air exposure to manganese may have negative neurodevelopmental effects; high levels of the metal correlate with lower IQ. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 25, 2017 Category: Consumer Health News Tags: Public Health Source Type: news

Medical News Today: Too much manganese may lead to fatal heart infection
New research finds that excessive intake of manganese, an essential nutrient in leafy vegetables, may lead to a Staphylococcus aureus heart infection. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 22, 2017 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Excess dietary manganese promotes staph heart infection
(Vanderbilt University Medical Center) Too much dietary manganese -- an essential trace mineral found in leafy green vegetables, fruits and nuts -- promotes infection of the heart by the bacterium Staphylococcus aureus. The findings, reported this week in Cell Host& Microbe, add to evidence that diet modifies risk for infection and suggest that people who have excess levels of tissue manganese, potentially from dietary supplements, may be at increased risk for staph infection of the heart. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 21, 2017 Category: Infectious Diseases Source Type: news

Higher manganese levels in children correlate with lower IQ scores, UC study finds
(University of Cincinnati Academic Health Center) A study led by environmental health researchers at the University of Cincinnati (UC) College of Medicine finds that children in East Liverpool, Ohio with higher levels of Manganese (Mn) had lower IQ scores. The research appears online in the journal NeuroToxicology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 21, 2017 Category: International Medicine & Public Health Source Type: news

Traces of Tattoo May Reach the Lymph Nodes
WEDNESDAY, Sept. 13, 2017 -- Microscopic particles from tattoos can travel within the body and reach the lymph nodes, researchers say. Along with pigments, tattoo inks contain preservatives and contaminants such as nickel, chromium, manganese and... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 13, 2017 Category: General Medicine Source Type: news

High dislocation density-induced large ductility in deformed and partitioned steels
A wide variety of industrial applications require materials with high strength and ductility. Unfortunately, the strategies for increasing material strength, such as processing to create line defects (dislocations), tend to decrease ductility. We developed a strategy to circumvent this in inexpensive, medium manganese steel. Cold rolling followed by low-temperature tempering developed steel with metastable austenite grains embedded in a highly dislocated martensite matrix. This deformed and partitioned (D and P) process produced dislocation hardening but retained high ductility, both through the glide of intensive mobile d...
Source: ScienceNOW - September 7, 2017 Category: Science Authors: He, B. B., Hu, B., Yen, H. W., Cheng, G. J., Wang, Z. K., Luo, H. W., Huang, M. X. Tags: Engineering, Materials Science reports Source Type: news

Trump ’ s Halt on Coal Mining Study Has Asbestos Implications
The U.S. Department of the Interior has ordered a halt to a study on the public health risks of mountaintop removal mining in Appalachia — an area ripe with natural asbestos deposits. A letter from the Interior Department on Monday directed the National Academies of Sciences, Engineering and Medicine to “cease all work” on the study, citing responsible spending of taxpayer dollars as the reason for the decision. The $1 million National Academies study began in 2016 and was expected to take two years to complete. It aimed to evaluate health risks of a common mining technique for people living near surfac...
Source: Asbestos and Mesothelioma News - August 24, 2017 Category: Environmental Health Authors: Matt Mauney Tags: Appalachian Mountains arsenic asbestos exposure Appalachia asbestos exposure coal mining asbestosis coal mining Bill Price Central Appalachia coal mining Appalachia Donald Trump Environmental Health Perspectives Glenda Owens House Co Source Type: news

Manganese in underground drinking water is cause for concern
(University of California - Riverside) Underground drinking water sources in parts of the US and three Asian countries may not be as safe as previously thought due to high levels of manganese, especially at shallow depths, according to a study led by a researcher at the University of California, Riverside. Manganese, a metal that is required by the body in tiny amounts, can be toxic at elevated levels, particularly in children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 24, 2017 Category: International Medicine & Public Health Source Type: news

Metal-catalyzed electrochemical diazidation of alkenes
We report an operationally simple and environmentally friendly protocol that converts alkenes and sodium azide—both readily available feedstocks—to 1,2-diazides. Powered by electricity and catalyzed by Earth-abundant manganese, this transformation proceeds under mild conditions and exhibits exceptional substrate generality and functional group compatibility. Using standard protocols, the resultant 1,2-diazides can be smoothly reduced to vicinal diamines in a single step, with high chemoselectivity. Mechanistic studies are consistent with metal-mediated azidyl radical transfer as the predominant pathway, enablin...
Source: ScienceNOW - August 10, 2017 Category: Science Authors: Fu, N., Sauer, G. S., Saha, A., Loo, A., Lin, S. Tags: Chemistry reports Source Type: news

Baby teeth link autism with metal uptake, in NIEHS-funded study
Baby teeth from children with autism contain more toxic lead and less zinc and manganese than in children without autism, say NIEHS-funded researchers. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - July 4, 2017 Category: Environmental Health Source Type: news

Low levels of manganese in welding fumes cause neurological problems
(Washington University School of Medicine) Welders exposed to airborne manganese at estimated levels under federal occupational safety standards exhibit neurological problems similar to Parkinson's disease, according to new research at Washington University School of Medicine in St. Louis. Further, the more they are exposed to manganese-containing welding fumes, the faster the workers' signs and symptoms worsen. The findings suggest that current safety standards may not adequately protect welders from the dangers of the job. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 28, 2016 Category: Global & Universal Source Type: news

Early exposure to too much manganese causes attention deficits in rats
Too much manganese early in development causes lasting attention deficits and other impairments in rats. Studies of children and adolescents have associated excess manganese in the diet with attention deficits, but confounding factors in those studies have made it impossible to show a cause and effect relationship. The new study is the first to establish a causal link between exposure to elevated manganese in the diet and attentional dysfunction in an animal model. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 23, 2016 Category: Science Source Type: news

Early exposure to manganese causes attention deficits in rats
(University of California - Santa Cruz) Too much manganese early in development causes lasting attention deficits and other impairments in rats. Studies of children and adolescents have associated excess manganese in the diet with attention deficits, but confounding factors in those studies have made it impossible to show a cause and effect relationship. The new study is the first to establish a causal link between exposure to elevated manganese in the diet and attentional dysfunction in an animal model. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 23, 2016 Category: Global & Universal Source Type: news

Neurotoxicity in the NICU: Is Manganese a Villain?Neurotoxicity in the NICU: Is Manganese a Villain?
Many preterm infants are receiving excessive amounts of a known neurotoxin. What's being done about manganese? Medscape Nurses (Source: Medscape Nurses Headlines)
Source: Medscape Nurses Headlines - March 14, 2016 Category: Nursing Tags: Nursing Viewpoint Source Type: news

The best natural sources of manganese
(NaturalNews) Manganese is a trace mineral that is present in only small amounts in our bodies. It is considered an essential nutrient and is responsible for a large number of biological roles, including proper enzyme functioning, wound healing, nutrient absorption and bone development... (Source: NaturalNews.com)
Source: NaturalNews.com - January 9, 2015 Category: Consumer Health News Source Type: news

Childhood exposure to manganese and postural instability in children living near a ferromanganese refinery in southeastern Ohio - Rugless F, Bhattacharya A, Succop P, Dietrich KN, Cox C, Alden J, Kuhnell P, Barnas M, Wright R, Parsons PJ, Praamsma ML, Palmer CD, Beidler C, Wittberg R, Haynes EN.
Airborne manganese (Mn) exposure can result in neurotoxicity and postural instability in occupationally exposed workers, yet few studies have explored the association ambient exposure to Mn in children and postural stability. The goal of this study was to ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - January 11, 2014 Category: Global & Universal Tags: Age: Infants and Children Source Type: news

Nutrition 101: Manganese
(HealthCastle.com) Manganese is a trace mineral present in tiny amounts in the body. It is found mostly in bones, the liver, the kidneys, and the pancreas. Reco​mme​nded Intake The Dietary Reference Intakes (DRI) for manganese are shown below: read more (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians - November 25, 2013 Category: Nutrition Source Type: news

Elevated manganese exposure and school-aged children's behavior: A gender-stratified analysis - Menezes-Filho JA, de Carvalho-Vivas CF, Viana GF, Ferreira JR, Nunes LS, Mergler D, Abreu N.
The objective of the present study was to examine behavioral ... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 19, 2013 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Welding Fume Judge Recommends Dissolving Consolidation Of Manganese Injury Cases
CLEVELAND - The multidistrict litigation created in June 2003 by the Judicial Panel on Multidistrict Litigation in the U.S. District Court for the Northern District of Ohio for personal injury claims allegedly caused by inhalation of welding fumes containing manganese was dissolved March 25 (In re: Welding Fume Products Liability Litigation, No. 03-17000, MDL 1535, N.D. Ohio; See 1/22/13, Page 35). (Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News)
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - April 13, 2013 Category: Medical Law Source Type: news

Property Damage Claims For Manganese Contamination Removed To Ohio Federal Court
TOLEDO, Ohio - The claims of more than 400 plaintiffs joined in a manganese exposure personal injury and property damage action were removed Jan. 18 to the U.S. District Court for the Northern District of Ohio; the steel mill owner defendant was granted in a Feb. 4 marginal order until March 7 to file an answer to the complaint (Michael F. Abrams, et al. v. Nucor Steel Marion Inc., No. 13-137, N.D. Ohio). (Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News)
Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - February 20, 2013 Category: Medical Law Source Type: news