Urinary lipoarabinomannan in individuals with sputum-negative pulmonary tuberculosis
CONCLUSIONS: The findings of this study suggest that individuals with smear-negative PTB and a urinary LAM value of >0.615 ng/ml were most likely to have microbiological confirmed TB while those with a LAM value <0.615 ng/ml >0.478 ng/ml are less likely and those with a value <0.478 ng/ml are unlikely to have microbiological confirmed TB.PMID:38577859 | DOI:10.4103/ijmr.ijmr_2074_22 (Source: Indian J Med Res)
Source: Indian J Med Res - April 5, 2024 Category: Research Authors: P Ajantha Man Mohan Puri Devika Tayal U Khalid Source Type: research
Diagnosis and management of intraspinal tuberculoma with osseous involvement: a case report
CONCLUSION: Intraspinal tuberculoma should be considered when an intraspinal mass is found with a history of tuberculosis, it can be effectively diagnosed by MRI and treated by the combination of medical and surgical treatments.PMID:38576994 | PMC:PMC10990343 | DOI:10.1097/MS9.0000000000001894 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Song Wu Fei Hu Bing Sun Yuting Yang Wenxin Zhang Yuan Ma Qing Ouyang Source Type: research
Therapeutic Potential of Morin Hydrate Against Rifampicin Induced Hepato and Renotoxicity in Albino Wistar Rats: Modulation of Organ Function, Oxidative Stress and Inflammatory Response
Indian J Clin Biochem. 2024 Apr;39(2):197-206. doi: 10.1007/s12291-023-01145-0. Epub 2023 Aug 4.ABSTRACTTuberculosis (TB) is a challenging public health issue, particularly in poor and developing countries. Rifampicin (RIF) is one of the most common first-line anti-TB drugs but it is known for its adverse effects on the hepato-renal system. The present study investigated the efficacy of morin hydrate (MH) in protecting hepato-renal damage inflicted by RIF in rats. RIF (50 mg/kg), and a combination of RIF (50 mg/kg) and MH (50 mg/kg) were administered orally for 4 weeks in rats. Silymarin (50 mg/kg) was used as a positive c...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Harvesh Kumar Rana Amit Kumar Singh Abhay Kumar Pandey Source Type: research
Protective Role of Vitamin D Against Development of Active Tuberculosis in Close Household Contacts of Pulmonary Tuberculosis Patients: A Prospective Cohort Study
Indian J Clin Biochem. 2024 Apr;39(2):248-256. doi: 10.1007/s12291-022-01110-3. Epub 2023 Jan 12.ABSTRACTVitamin-D is known to promote innate immune responses by acting as a cofactor of VDR for induction of antimicrobial peptides like cathelicidin. Close household contacts of pulmonary tuberculosis patients are at high risk of active infection, Therefore, possible role of vitamin-D in TB prevention through cathelicidin production was studied in high-risk household contacts (HHCs) of pulmonary tuberculosis (PTB) patients. 20 HHCs of PTB patients were recruited and followed up for one year. Levels of vitamin-D (25(OH)D) and ...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Sudhasini Panda Ambrish Tiwari Vivek Kumar Kalpana Luthra Kuldeep Kumar Archana Singh Source Type: research
Tuberculosis in pregnancy and adverse neonatal outcomes in two peruvian hospitals
CONCLUSION: Pulmonary TB in pregnancy was jointly and independently associated with adverse neonatal outcomes, including LBW, prematurity, and being SGA.PMID:38577130 | PMC:PMC10992712 | DOI:10.1016/j.eurox.2024.100304 (Source: Reproductive Biology)
Source: Reproductive Biology - April 5, 2024 Category: Reproduction Medicine Authors: Noelia V Garay-Aguilar Lizbeth R Reynoso-Rosales Anita P Llamo-Vilcherrez Carlos J Toro-Huamanchumo Source Type: research
Urinary lipoarabinomannan in individuals with sputum-negative pulmonary tuberculosis
CONCLUSIONS: The findings of this study suggest that individuals with smear-negative PTB and a urinary LAM value of >0.615 ng/ml were most likely to have microbiological confirmed TB while those with a LAM value <0.615 ng/ml >0.478 ng/ml are less likely and those with a value <0.478 ng/ml are unlikely to have microbiological confirmed TB.PMID:38577859 | DOI:10.4103/ijmr.ijmr_2074_22 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - April 5, 2024 Category: Biomedical Science Authors: P Ajantha Man Mohan Puri Devika Tayal U Khalid Source Type: research
Urinary lipoarabinomannan in individuals with sputum-negative pulmonary tuberculosis
CONCLUSIONS: The findings of this study suggest that individuals with smear-negative PTB and a urinary LAM value of >0.615 ng/ml were most likely to have microbiological confirmed TB while those with a LAM value <0.615 ng/ml >0.478 ng/ml are less likely and those with a value <0.478 ng/ml are unlikely to have microbiological confirmed TB.PMID:38577859 | DOI:10.4103/ijmr.ijmr_2074_22 (Source: Indian J Med Res)
Source: Indian J Med Res - April 5, 2024 Category: Research Authors: P Ajantha Man Mohan Puri Devika Tayal U Khalid Source Type: research
Ruxolitinib associated psoas muscle tuberculosis abscess in a primary myelofibrosis woman: A case report and literature review
Medicine (Baltimore). 2024 Apr 5;103(14):e37653. doi: 10.1097/MD.0000000000037653.ABSTRACTRATIONALE: Primary myelofibrosis is a subtype of myeloproliferative neoplasm that leads to bone marrow fibrosis. Historically, the only curative option for primary myelofibrosis was allogeneic hematopoietic stem cell transplant. Ruxolitinib, a Janus kinase inhibitor, is now used for the treatment of primary myelofibrosis and polycythemia vera. It effectively improves symptoms related to splenomegaly and anemia. However, its association with the development of opportunistic infections has been observed in clinical studies and practical...
Source: Herpes - April 5, 2024 Category: Infectious Diseases Authors: Chi-Yu Chen Tun-Chieh Chen Source Type: research
Diagnosis and management of intraspinal tuberculoma with osseous involvement: a case report
CONCLUSION: Intraspinal tuberculoma should be considered when an intraspinal mass is found with a history of tuberculosis, it can be effectively diagnosed by MRI and treated by the combination of medical and surgical treatments.PMID:38576994 | PMC:PMC10990343 | DOI:10.1097/MS9.0000000000001894 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Song Wu Fei Hu Bing Sun Yuting Yang Wenxin Zhang Yuan Ma Qing Ouyang Source Type: research
Therapeutic Potential of Morin Hydrate Against Rifampicin Induced Hepato and Renotoxicity in Albino Wistar Rats: Modulation of Organ Function, Oxidative Stress and Inflammatory Response
Indian J Clin Biochem. 2024 Apr;39(2):197-206. doi: 10.1007/s12291-023-01145-0. Epub 2023 Aug 4.ABSTRACTTuberculosis (TB) is a challenging public health issue, particularly in poor and developing countries. Rifampicin (RIF) is one of the most common first-line anti-TB drugs but it is known for its adverse effects on the hepato-renal system. The present study investigated the efficacy of morin hydrate (MH) in protecting hepato-renal damage inflicted by RIF in rats. RIF (50 mg/kg), and a combination of RIF (50 mg/kg) and MH (50 mg/kg) were administered orally for 4 weeks in rats. Silymarin (50 mg/kg) was used as a positive c...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Harvesh Kumar Rana Amit Kumar Singh Abhay Kumar Pandey Source Type: research
Protective Role of Vitamin D Against Development of Active Tuberculosis in Close Household Contacts of Pulmonary Tuberculosis Patients: A Prospective Cohort Study
Indian J Clin Biochem. 2024 Apr;39(2):248-256. doi: 10.1007/s12291-022-01110-3. Epub 2023 Jan 12.ABSTRACTVitamin-D is known to promote innate immune responses by acting as a cofactor of VDR for induction of antimicrobial peptides like cathelicidin. Close household contacts of pulmonary tuberculosis patients are at high risk of active infection, Therefore, possible role of vitamin-D in TB prevention through cathelicidin production was studied in high-risk household contacts (HHCs) of pulmonary tuberculosis (PTB) patients. 20 HHCs of PTB patients were recruited and followed up for one year. Levels of vitamin-D (25(OH)D) and ...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Sudhasini Panda Ambrish Tiwari Vivek Kumar Kalpana Luthra Kuldeep Kumar Archana Singh Source Type: research
Tuberculosis in pregnancy and adverse neonatal outcomes in two peruvian hospitals
CONCLUSION: Pulmonary TB in pregnancy was jointly and independently associated with adverse neonatal outcomes, including LBW, prematurity, and being SGA.PMID:38577130 | PMC:PMC10992712 | DOI:10.1016/j.eurox.2024.100304 (Source: Reproductive Biology)
Source: Reproductive Biology - April 5, 2024 Category: Reproduction Medicine Authors: Noelia V Garay-Aguilar Lizbeth R Reynoso-Rosales Anita P Llamo-Vilcherrez Carlos J Toro-Huamanchumo Source Type: research
Urinary lipoarabinomannan in individuals with sputum-negative pulmonary tuberculosis
CONCLUSIONS: The findings of this study suggest that individuals with smear-negative PTB and a urinary LAM value of >0.615 ng/ml were most likely to have microbiological confirmed TB while those with a LAM value <0.615 ng/ml >0.478 ng/ml are less likely and those with a value <0.478 ng/ml are unlikely to have microbiological confirmed TB.PMID:38577859 | DOI:10.4103/ijmr.ijmr_2074_22 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - April 5, 2024 Category: Biomedical Science Authors: P Ajantha Man Mohan Puri Devika Tayal U Khalid Source Type: research
Urinary lipoarabinomannan in individuals with sputum-negative pulmonary tuberculosis
CONCLUSIONS: The findings of this study suggest that individuals with smear-negative PTB and a urinary LAM value of >0.615 ng/ml were most likely to have microbiological confirmed TB while those with a LAM value <0.615 ng/ml >0.478 ng/ml are less likely and those with a value <0.478 ng/ml are unlikely to have microbiological confirmed TB.PMID:38577859 | DOI:10.4103/ijmr.ijmr_2074_22 (Source: Indian J Med Res)
Source: Indian J Med Res - April 5, 2024 Category: Research Authors: P Ajantha Man Mohan Puri Devika Tayal U Khalid Source Type: research
Diagnosis and management of intraspinal tuberculoma with osseous involvement: a case report
CONCLUSION: Intraspinal tuberculoma should be considered when an intraspinal mass is found with a history of tuberculosis, it can be effectively diagnosed by MRI and treated by the combination of medical and surgical treatments.PMID:38576994 | PMC:PMC10990343 | DOI:10.1097/MS9.0000000000001894 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Song Wu Fei Hu Bing Sun Yuting Yang Wenxin Zhang Yuan Ma Qing Ouyang Source Type: research
