Genetic characterization of SARS-CoV-2 & implications for epidemiology, diagnostics & vaccines in India.
Genetic characterization of SARS-CoV-2 & implications for epidemiology, diagnostics & vaccines in India. Indian J Med Res. 2020 Sep 08;: Authors: Abraham P, Cherian S, Potdar V PMID: 32896836 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - September 8, 2020 Category: Research Authors: Abraham P, Cherian S, Potdar V Tags: Indian J Med Res Source Type: research

Economics & ethics of the COVID-19 vaccine: How prepared are we?
Economics & ethics of the COVID-19 vaccine: How prepared are we? Indian J Med Res. 2020 Sep 07;: Authors: Gupta I, Baru R PMID: 32896834 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - September 7, 2020 Category: Research Authors: Gupta I, Baru R Tags: Indian J Med Res Source Type: research

HIV self-test during the time of COVID-19, India.
PMID: 32896835 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - September 7, 2020 Category: Research Authors: Rao A Tags: Indian J Med Res Source Type: research

The enigmatic COVID-19 pandemic.
PMID: 32893843 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - September 4, 2020 Category: Research Authors: Bhatia R, Abraham P Tags: Indian J Med Res Source Type: research

Pooled testing for COVID-19 diagnosis by real-time RT-PCR: A multi-site comparative evaluation of 5- & 10-sample pooling.
We report here a comparative analysis of pooled testing for 5- and 10-sample pools by real-time RT-PCR across 10 COVID-19 testing laboratories in India. Methods: : Ten virus research and diagnostic laboratories (VRDLs) testing for COVID-19 by real-time RT-PCR participated in this evaluation. At each laboratory, 100 nasopharyngeal swab samples including 10 positive samples were used to create 5- and 10-sample pools with one positive sample in each pool. RNA extraction and real-time RT-PCR for SARS-CoV-2-specific E gene target were performed for individual positive samples as well as pooled samples. Concordance between ...
Source: Indian J Med Res - September 4, 2020 Category: Research Authors: Praharaj I, Jain A, Singh M, Balakrishnan A, Dhodapkar R, Borkakoty B, Ashok M, Das P, Biswas D, Kalawat U, Turuk J, Sugunan AP, Prakash S, Singh AK, Barathidasan R, Subhadra S, Sabat J, Manjunath MJ, Kanta P, Mudhigeti N, Hazarika R, Mishra H, Abhishek K Tags: Indian J Med Res Source Type: research

Recent developments in COVID-19 therapeutics & current evidence for COVID-19-associated multisystem inflammatory syndrome.
Recent developments in COVID-19 therapeutics & current evidence for COVID-19-associated multisystem inflammatory syndrome. Indian J Med Res. 2020 Aug 31;: Authors: Gupta S, Kaushik A, Sood M PMID: 32883919 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 31, 2020 Category: Research Authors: Gupta S, Kaushik A, Sood M Tags: Indian J Med Res Source Type: research

Authors' response.
, Manesh A, Karthik R, Abraham OC PMID: 32883920 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 31, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Multi-layered masks to combat COVID-19.
PMID: 32859865 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 28, 2020 Category: Research Authors: Rawal A Tags: Indian J Med Res Source Type: research

Neutralizing antibody responses to SARS-CoV-2 in COVID-19 patients.
Abstract Background & objectives: : The global pandemic caused by SARS-CoV-2 virus has challenged public health system worldwide due to the unavailability of approved preventive and therapeutic options. Identification of neutralizing antibodies (NAb) and understanding their role is important. However, the data on kinetics of NAb response among COVID-19 patients are unclear. To understand the NAb response in COVID-19 patients, we compared the findings of microneutralization test (MNT) and plaque reduction neutralization test (PRNT) for the SARS-CoV-2. Further, the kinetics of NAb response among COVID-19 patient...
Source: Indian J Med Res - August 28, 2020 Category: Research Authors: Deshpande GR, Sapkal GN, Tilekar BN, Yadav PD, Gurav Y, Gaikwad S, Kaushal H, Deshpande KS, Kaduskar O, Sarkale P, Baradkar S, Suryawanshi A, Lakra R, Sugunan AP, Balakrishnan A, Abraham P, Salve P, COVID Support Team Tags: Indian J Med Res Source Type: research

Identification of SARS-CoV-2 clusters from symptomatic cases in India.
PMID: 32859867 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 28, 2020 Category: Research Authors: Jain P, Prakash O, Nyayanit DA, Verma AK, Yadav PD, Khan DN, Prakash S, Mishra H, Reddy H, Agarwal A, Bhatt MB, Jain A Tags: Indian J Med Res Source Type: research

Will bacille Calmette-Guerin immunization arrest the COVID-19 pandemic?
PMID: 32859863 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 24, 2020 Category: Research Authors: Ehtesham NZ, Samal J, Ahmad F, Arish M, Naz F, Alam A, Agrawal U, Hasnain SE Tags: Indian J Med Res Source Type: research

Neurological manifestations of COVID-19: A brief review.
Abstract The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been predominantly a respiratory manifestation. Currently, with evolving literature, neurological signs are being increasingly recognized. Studies have reported that SARS-CoV-2 affects all aspects of the nervous system including the central nervous system (CNS), peripheral nervous system (PNS) and the muscular system as well. Not all patients have reverse transcription-polymerase chain reaction positive for the virus in the cerebrospinal fluid, and diagnosing the association of the virus with the myriad of n...
Source: Indian J Med Res - August 24, 2020 Category: Research Authors: Sachdev K, Agrawal S, Ish P, Gupta N, Raheja K Tags: Indian J Med Res Source Type: research

Gargle lavage as a viable alternative to swab for detection of SARS-CoV-2.
Abstract Background & objectives: : Nasopharyngeal and oropharyngeal swab (NPS and OPS) collection is widely accepted as the preferred method for obtaining respiratory samples. However, it has certain disadvantages which may be overcome by gargling. The primary objective of this study was to assess agreement between gargle lavage and swab as an appropriate respiratory sample for the detection of SARS-CoV-2. The secondary objective was to assess the patient acceptability of the two sampling methods. Methods: : It was a cross-sectional study done at a tertiary care hospital in New Delhi, India, on 50 confir...
Source: Indian J Med Res - August 20, 2020 Category: Research Authors: Mittal A, Gupta A, Kumar S, Surjit M, Singh B, Soneja M, Soni KD, Khan AR, Singh K, Naik S, Kumar A, Aggarwal R, Nischal N, Sinha S, Trikha A, Wig N Tags: Indian J Med Res Source Type: research

Epidemiological & clinical characteristics & early outcome of COVID-19 patients in a tertiary care teaching hospital in India: A preliminary analysis.
In this study we describe the epidemiological data, comorbidities, clinical symptoms, severity of illness and early outcome of patients with coronavirus disease 2019 (COVID-19) from a tertiary care teaching hospital in New Delhi, India. Methods: : In this preliminary analysis of a prospective observational study, all adult patients admitted to the screening intensive care unit (ICU) of the institute who fulfilled the WHO case definition of COVID-19 and confirmed to have SARS-CoV-2 infection by reverse transcription-polymerase chain reaction were included. Demographics, clinical data and 24 h outcome were assessed. ...
Source: Indian J Med Res - August 18, 2020 Category: Research Authors: Kayina CA, Haritha D, Soni L, Behera S, Nair PR, Gouri M, Girish K, Deeparaj L, Maitra S, Anand RK, Ray BR, Baidya DK, Subramaniam R Tags: Indian J Med Res Source Type: research

Hydroxychloroquine for prophylaxis in COVID-19: Need to revisit dosing regimen.
PMID: 32811798 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 17, 2020 Category: Research Authors: Pareek A, Bhandari S, Mehta RT Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32811799 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 17, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

A preliminary study on contact tracing & transmission chain in a cluster of 17 cases of severe acute respiratory syndrome coronavirus 2 infection in Basti, Uttar Pradesh, India.
A preliminary study on contact tracing & transmission chain in a cluster of 17 cases of severe acute respiratory syndrome coronavirus 2 infection in Basti, Uttar Pradesh, India. Indian J Med Res. 2020 Aug 17;: Authors: Kant R, Zaman K, Shankar P, Yadav R, RMRC GKP COVID Diagnostic Team Abstract Background & objectives: : Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly, causing unprecedented case fatalities across the world. The first laboratory-confirmed case of COVID-19 and also the first death associated with the disease in the eastern part of Uttar ...
Source: Indian J Med Res - August 17, 2020 Category: Research Authors: Kant R, Zaman K, Shankar P, Yadav R, RMRC GKP COVID Diagnostic Team Tags: Indian J Med Res Source Type: research

SARS-CoV-2 infection among healthcare workers in India: Limitations of the case-control investigation.
PMID: 32773426 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 4, 2020 Category: Research Authors: Niranjan V, Kinnersley N Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773427 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 4, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Prophylactic use of hydroxychloroquine among healthcare workers in a case-control study.
PMID: 32773428 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 4, 2020 Category: Research Authors: Kunte R, Yadav AK, Faujdar DS, Sahu R, Basannar D, Patrikar S, Chatterjee K, Gupta RM, Naithani N Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773429 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 4, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Observations on article on healthcare workers & SARS-CoV-2 infection.
Observations on article on healthcare workers & SARS-CoV-2 infection. Indian J Med Res. 2020 Aug 03;: Authors: Kulkarni AP PMID: 32773422 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 3, 2020 Category: Research Authors: Kulkarni AP Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773423 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 3, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Effect of quantitative real-time RT-PCR reaction sensitivity in determining the efficacy of HCQ prophylaxis for COVID-1.
PMID: 32773424 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 3, 2020 Category: Research Authors: Gouda D, Goudra B Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773425 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - August 3, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Transcriptome & viral growth analysis of SARS-CoV-2-infected Vero CCL-81 cells.
This study was undertaken to understand the transcription pattern of the SARS-CoV-2 genes in the Vero CCL-81 cells during the course of infection. Methods: : Vero CCL-81 cells were infected with the SARS-CoV-2 virus inoculum having a 0.1 multiplicity of infection. The supernatants and cell pellets were harvested after centrifugation at different time points, post-infection. The 50% tissue culture infective dose (TCID 50") and cycle threshold (Ct) values of the E and the RdRp-2 genes were calculated. Next-generation sequencing of the harvested sample was carried out to observe the expression pattern of the virus b...
Source: Indian J Med Res - July 30, 2020 Category: Research Authors: Nyayanit DA, Sarkale P, Baradkar S, Patil S, Yadav PD, Shete-Aich A, Kalele K, Gawande P, Majumdar T, Jain R, Sapkal G Tags: Indian J Med Res Source Type: research

Geographical & seasonal variation in COVID-19 related mortality.
Geographical & seasonal variation in COVID-19 related mortality. Indian J Med Res. 2020 Jul 30;: Authors: Badwe RA, Dikshit R, Chaturvedi P, Gupta S PMID: 32773421 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 30, 2020 Category: Research Authors: Badwe RA, Dikshit R, Chaturvedi P, Gupta S Tags: Indian J Med Res Source Type: research

Observations on healthcare workers & SARS-CoV-2 infection.
Observations on healthcare workers & SARS-CoV-2 infection. Indian J Med Res. 2020 Jul 24;: Authors: Barde P, Sarkate P, Gaikwad N PMID: 32773418 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 24, 2020 Category: Research Authors: Barde P, Sarkate P, Gaikwad N Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773419 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 24, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Quasispecies analysis of the SARS-CoV-2 from representative clinical samples: A preliminary analysis.
PMID: 32773417 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 23, 2020 Category: Research Authors: Nyayanit DA, Yadav PD, Kharde R, Shete-Aich A Tags: Indian J Med Res Source Type: research

Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India.
Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. Indian J Med Res. 2020 Jul 22;: Authors: Mohan A, Tiwari P, Bhatnagar S, Patel A, Maurya A, Dar L, Pahuja S, Garg R, Gupta N, Sahoo B, Gupta R, Meena VP, Vig S, Pandit A, Mittal S, Madan K, Hadda V, Dwivedi T, Choudhary A, Brijwal M, Soneja M, Guleria R, Ratre B, Kumar B, Bhopale S, Panda S, Singh AR, Singh S, Wundavalli L Abstract Background & objectives: : In December 2019, a novel coronavirus (SARS-CoV-2) emerged in China and rapidly spread globally including India. The ch...
Source: Indian J Med Res - July 22, 2020 Category: Research Authors: Mohan A, Tiwari P, Bhatnagar S, Patel A, Maurya A, Dar L, Pahuja S, Garg R, Gupta N, Sahoo B, Gupta R, Meena VP, Vig S, Pandit A, Mittal S, Madan K, Hadda V, Dwivedi T, Choudhary A, Brijwal M, Soneja M, Guleria R, Ratre B, Kumar B, Bhopale S, Panda S, Sin Tags: Indian J Med Res Source Type: research

Hydroxychloroquine for chemoprophylaxis in COVID-19: A case of motivated perception?
PMID: 32773415 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 22, 2020 Category: Research Authors: Manjunath BG, Tyagi D, Chaudhry D, Singh PK Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773416 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 22, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Coronavirus disease 2019 in children: Clinical & epidemiological implications.
Coronavirus disease 2019 in children: Clinical & epidemiological implications. Indian J Med Res. 2020 Jul 17;: Authors: Kuttiatt VS, Abraham PR, Menon RP, Vaidya PC, Rahi M Abstract Despite the global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there are limited data emerging in children. This review provides an update on clinical features, diagnosis, epidemiology, management and prevention of coronavirus disease 2019 (COVID-19) in children. Specific characteristics noted in children and their implications in disease management as well as transmission contr...
Source: Indian J Med Res - July 17, 2020 Category: Research Authors: Kuttiatt VS, Abraham PR, Menon RP, Vaidya PC, Rahi M Tags: Indian J Med Res Source Type: research

Hydroxychloroquine prophylaxis for SARS-CoV-2 infection among healthcare workers.
PMID: 32773410 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 17, 2020 Category: Research Authors: Karim HMR, Ahmed G Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773411 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 17, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

False reassurance or inadequate drug levels?
PMID: 32773412 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 17, 2020 Category: Research Authors: Tirlangi P, Khan AR, Desai D, Soneja M Tags: Indian J Med Res Source Type: research

Authors' response.
T, Singh KJ, Rasaily R, Singh R, Das S, Singh H, Praharaj I, Gangakhedkar RR, Bhargava B, Panda S PMID: 32773413 [PubMed - as supplied by publisher] (Source: Indian J Med Res)
Source: Indian J Med Res - July 17, 2020 Category: Research Authors: Authors' response. Tags: Indian J Med Res Source Type: research

Sickle cell disease: Progress made & challenges ahead.
Sickle cell disease: Progress made & challenges ahead. Indian J Med Res. 2020 Jun;151(6):505-508 Authors: Odame I, Jain D PMID: 32719221 [PubMed - in process] (Source: Indian J Med Res)
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Odame I, Jain D Tags: Indian J Med Res Source Type: research

Epicardial adipose tissue: An anatomic component of obesity & metabolic syndrome in close proximity to myocardium & coronary arteries.
Epicardial adipose tissue: An anatomic component of obesity & metabolic syndrome in close proximity to myocardium & coronary arteries. Indian J Med Res. 2020 Jun;151(6):509-512 Authors: Ndrepepa G PMID: 32719222 [PubMed - in process] (Source: Indian J Med Res)
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Ndrepepa G Tags: Indian J Med Res Source Type: research

White paper on smokeless tobacco & women's health in India.
White paper on smokeless tobacco & women's health in India. Indian J Med Res. 2020 Jun;151(6):513-521 Authors: Singh S, Jain P, Singh PK, Reddy KS, Bhargava B Abstract Smokeless tobacco (SLT) use is widespread across many nations and populations, and India shares more than three-quarters of the global burden of SLT consumption. Tobacco use in India has been largely viewed as a male-dominant behaviour. However, evidence from medical, social and behavioural sciences show significant SLT use among women and young girls. This paper highlights key dimensions of SLT use among women in India including pr...
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Singh S, Jain P, Singh PK, Reddy KS, Bhargava B Tags: Indian J Med Res Source Type: research

Occult drug resistance in tuberculosis: Emerging issues, upcoming challenges & possible solutions.
Occult drug resistance in tuberculosis: Emerging issues, upcoming challenges & possible solutions. Indian J Med Res. 2020 Jun;151(6):522-524 Authors: Mishra B, Mohapatra PR PMID: 32719224 [PubMed - in process] (Source: Indian J Med Res)
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Mishra B, Mohapatra PR Tags: Indian J Med Res Source Type: research

Why there are no effective herbal antidotes against snake venom available in India?
PMID: 32719225 [PubMed - in process] (Source: Indian J Med Res)
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Gomes A, Ghosh S, Gomes A Tags: Indian J Med Res Source Type: research

Allergic bronchopulmonary aspergillosis.
Abstract Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease caused by immunologic reactions initiated against Aspergillus fumigatus colonizing the airways of patients with asthma and cystic fibrosis. The common manifestations include treatment-resistant asthma, transient and fleeting pulmonary opacities and bronchiectasis. It is believed that globally there are about five million cases of ABPA, with India alone accounting for about 1.4 million cases. The occurrence of ABPA among asthmatic patients in special clinics may be as high as 13 per cent. Thus, a high degree of suspicion for ABPA sho...
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Agarwal R, Sehgal IS, Dhooria S, Muthu V, Prasad KT, Bal A, Aggarwal AN, Chakrabarti A Tags: Indian J Med Res Source Type: research

Indian Council of Medical Research's International Collaboration & Partnerships; Health Ministry's Screening Committee: Facts, figures & procedures.
This article summarizes the international partnerships of ICMR as well as the details of guidelines regarding submission of international collaborative research projects for the Health Ministry's Screening Committee (HMSC), which is a mandatory requirement before undertaking such projects. PMID: 32719227 [PubMed - in process] (Source: Indian J Med Res)
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Kumar M, Sandhu H, Roshan R Tags: Indian J Med Res Source Type: research

Pathogenic gene expression of epicardial adipose tissue in patients with coronary artery disease.
This study was undertaken to find out the difference in gene expression of epicardial fat in CAD and non-CAD patients. Methods: Twenty seven patients undergoing coronary artery bypass graft (CABG) and 16 controls (non-CAD patients undergoing valvular heart surgeries) were included in the study and their EAT samples were obtained. Gene expressions of uncoupling protein-1, monocyte chemoattractant protein-1 (MCP-1), adiponectin, adenosine A1 receptor (ADORA-1), vascular cell adhesion molecule-1 (VCAM-1) and tumour necrosis factor-alpha (TNF-α) were studied by real-time reverse transcription-polymerase chain reacti...
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Sahasrabuddhe AV, Pitale SU, Sivanesan SD, Deshpande PK, Deshpande SP, Daiwile A Tags: Indian J Med Res Source Type: research

Findings from the 2017 HIV estimation round & trend analysis of key indicators 2010-2017: Evidence for prioritising HIV/AIDS programme in India.
The objective of this study was to describe India's biennial HIV estimation 2017 process, data inputs, tool, methodology and epidemiological assumptions used to generate the HIV estimates and trends of key indicators for 2010-2017 at national and State/Union Territory levels. Methods: Demographic Projection (DemProj) and AIDS Impact Modules (AIM) of Spectrum 5.63 software recommended by the United Nations Programme on HIV and AIDS Global Reference Group on HIV Estimates, Modelling and Projections, were used for generating HIV estimations on key indicators. HIV sentinel surveillance, epidemiological and programme data ...
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Sahu D, Kumar P, Chandra N, Rajan S, Shukla DK, Venkatesh S, Nair S, Kumar A, Singh J, Reddy S, Godbole S, Elangovan A, Saha MK, Rai S, Lakshmi PVM, Gambhir T, Ammassari S, Joshi D, Das A, Bakshi P, Chakraborty S, Palkar A, Singh SK, Reddy DCS, Kant S, Pa Tags: Indian J Med Res Source Type: research

Proactive preparedness for Cat Que virus: An Orthobunyavirus existing in India.
Abstract Background & objectives: The presence of Cat Que virus (CQV) in Culex mosquitoes and pigs has been reported in China and Vietnam. Due to the spread of similar species of the Culex mosquitoes in India, there is a need to understand the replication kinetics of this virus in mosquito models. As a part of preparedness and to identify the presence of this CQV in humans and swine, this study was carried out to develop diagnostic tests. Methods: Serological and molecular diagnostic assays were developed for testing the mosquito population, human and swine serum samples. In this line, RNA-dependent RNA p...
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Shete A, Yadav PD, Gokhale M, Jain R, Pardeshi P, Majumdar T, Mourya DT Tags: Indian J Med Res Source Type: research

Comparison of efficacy of potassium titanyl phosphate laser & diode laser in the management of inferior turbinate hypertrophy: A randomized controlled trial.
This study was undertaken to compare the efficacy of potassium titanyl phosphate (KTP) laser and diode laser in the reduction of the turbinate size. Methods: This randomized controlled trial included 209 patients with ITH. Pre-operative symptoms were assessed based on the Nasal Obstruction Symptom Evaluation (NOSE) score. Diagnostic nasal endoscopy was done to rule out other nasal sinuses. Nasal mucociliary clearance was measured by saccharin transit time (STT). Postoperatively, the NOSE score, STT and complications were assessed at days one and two, at one week, one month and three months. Results: Of the 209 pa...
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Ravichandran SP, Ramasamy K, Parida PK, Alexander A, Ganesan S, Saxena SK Tags: Indian J Med Res Source Type: research

Distribution of carbapenemase genes in clinical isolates of Acinetobacter baumannii & a comparison of MALDI-TOF mass spectrometry-based detection of carbapenemase production with other phenotypic methods.
Distribution of carbapenemase genes in clinical isolates of Acinetobacter baumannii & a comparison of MALDI-TOF mass spectrometry-based detection of carbapenemase production with other phenotypic methods. Indian J Med Res. 2020 Jun;151(6):585-591 Authors: Sharma M, Singhal L, Gautam V, Ray P Abstract Background & objectives: Carbapenemase-producing Acinetobacter baumannii (CRAB) poses a continuous threat to the current antimicrobial era with its alarming spread in critical care settings. The present study was conducted to evaluate the diagnostic potential of phenotypic methods for carbapenemas...
Source: Indian J Med Res - June 1, 2020 Category: Research Authors: Sharma M, Singhal L, Gautam V, Ray P Tags: Indian J Med Res Source Type: research