Neutralizing antibody responses to SARS-CoV-2 Omicron variants: Post six months following two-dose & amp; three-dose vaccination of ChAdOx1 nCoV-19 or BBV152
CONCLUSIONS: Persistence of NAb responses was comparable in individuals with two- and three-dose groups post six months of vaccination. Among the Omicron sub-variants, XBB.1 showed marked neutralization escape, thus pointing towards an eventual immune escape, which may cause more infections. Further, the correlation of study data with complete clinical profile of the participants along with observations for cell-mediated immunity may provide a clear picture for the sustained protection due to three-dose vaccination as well as hybrid immunity against the newer variants.PMID:38517215 | DOI:10.4103/ijmr.ijmr_948_23 (Source: Indian J Med Res)
Source: Indian J Med Res - March 22, 2024 Category: Research Authors: Pragya D Yadav Viren Sardana Gururaj Rao Deshpande Pradnya V Shinde Jeromie Wesley Vivian Thangaraj Leyanna S George Gajanan N Sapkal Deepak Y Patil Rima R Sahay Anita M Shete Madhavi Joshi Manoj Murhekar Sheela Godbole Nivedita Gupta Satyartha Prakash Ma Source Type: research

Does Lake Louise questionnaire interpret high-altitude headache as acute mountain sickness? Experience in the western Himalayas
CONCLUSIONS: The findings of this study suggest that LLQ has a tendency of overestimating AMS by including HAH cases. Furthermore differential parameters exhibit differences when AMS and HAH are considered separately. Re-inductees showed a lower incidence of HAH and AMS.PMID:38517219 | DOI:10.4103/ijmr.ijmr_2127_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 22, 2024 Category: Research Authors: Abhilash Unnikrishnan Atul Shekhar Dharmendra Kumar Raksha Jaipurkar Gaurav Sikri Krishan Singh Rahul Manral Source Type: research

Neutralizing antibody responses to SARS-CoV-2 Omicron variants: Post six months following two-dose & amp; three-dose vaccination of ChAdOx1 nCoV-19 or BBV152
CONCLUSIONS: Persistence of NAb responses was comparable in individuals with two- and three-dose groups post six months of vaccination. Among the Omicron sub-variants, XBB.1 showed marked neutralization escape, thus pointing towards an eventual immune escape, which may cause more infections. Further, the correlation of study data with complete clinical profile of the participants along with observations for cell-mediated immunity may provide a clear picture for the sustained protection due to three-dose vaccination as well as hybrid immunity against the newer variants.PMID:38517215 | DOI:10.4103/ijmr.ijmr_948_23 (Source: Indian J Med Res)
Source: Indian J Med Res - March 22, 2024 Category: Research Authors: Pragya D Yadav Viren Sardana Gururaj Rao Deshpande Pradnya V Shinde Jeromie Wesley Vivian Thangaraj Leyanna S George Gajanan N Sapkal Deepak Y Patil Rima R Sahay Anita M Shete Madhavi Joshi Manoj Murhekar Sheela Godbole Nivedita Gupta Satyartha Prakash Ma Source Type: research

Does Lake Louise questionnaire interpret high-altitude headache as acute mountain sickness? Experience in the western Himalayas
CONCLUSIONS: The findings of this study suggest that LLQ has a tendency of overestimating AMS by including HAH cases. Furthermore differential parameters exhibit differences when AMS and HAH are considered separately. Re-inductees showed a lower incidence of HAH and AMS.PMID:38517219 | DOI:10.4103/ijmr.ijmr_2127_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 22, 2024 Category: Research Authors: Abhilash Unnikrishnan Atul Shekhar Dharmendra Kumar Raksha Jaipurkar Gaurav Sikri Krishan Singh Rahul Manral Source Type: research

Evaluation of molecular diagnostic test for detection of adult pulmonary tuberculosis: A generic protocol
DISCUSSION: TB diagnosis poses many challenges as it differs with type of disease, age group, clinical settings and type of diagnostic tests/kits used. Globally, different protocols are used by several investigators. This protocol provides standard methods for the validation of molecular tests for diagnosis of adult pulmonary TB, which can be adopted by investigators.PMID:38511943 | DOI:10.4103/ijmr.ijmr_2316_23 (Source: Indian J Med Res)
Source: Indian J Med Res - March 21, 2024 Category: Research Authors: Madhumathi Jayaprakasam Ravindra Mohan Pandey Hansraj Choudhary Sivakumar Shanmugam Gomathi N Sivaramakrishnan Nivedita Gupta Source Type: research

Molecular detection of Orientia tsutsugamushi in ectoparasites & amp; their small mammal hosts captured from scrub typhus endemic areas in Madurai district, India
CONCLUSIONS: The outcome of the present investigations widened our scope on the pathogens present in ectoparasites and rodents/shrews from this area. This will help to formulate the required vector control methods to combat zoonotic diseases.PMID:38494626 | DOI:10.4103/ijmr.ijmr_3530_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 18, 2024 Category: Research Authors: R Govindarajan S Gowri Sankar M Senthil Kumar V Rajamannar R Krishnamoorthi A Alwin Prem Anand Ashwani Kumar P Philip Samuel Source Type: research

Molecular detection of Orientia tsutsugamushi in ectoparasites & amp; their small mammal hosts captured from scrub typhus endemic areas in Madurai district, India
CONCLUSIONS: The outcome of the present investigations widened our scope on the pathogens present in ectoparasites and rodents/shrews from this area. This will help to formulate the required vector control methods to combat zoonotic diseases.PMID:38494626 | DOI:10.4103/ijmr.ijmr_3530_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 18, 2024 Category: Research Authors: R Govindarajan S Gowri Sankar M Senthil Kumar V Rajamannar R Krishnamoorthi A Alwin Prem Anand Ashwani Kumar P Philip Samuel Source Type: research

Molecular detection of Orientia tsutsugamushi in ectoparasites & amp; their small mammal hosts captured from scrub typhus endemic areas in Madurai district, India
CONCLUSIONS: The outcome of the present investigations widened our scope on the pathogens present in ectoparasites and rodents/shrews from this area. This will help to formulate the required vector control methods to combat zoonotic diseases.PMID:38494626 | DOI:10.4103/ijmr.ijmr_3530_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 18, 2024 Category: Research Authors: R Govindarajan S Gowri Sankar M Senthil Kumar V Rajamannar R Krishnamoorthi A Alwin Prem Anand Ashwani Kumar P Philip Samuel Source Type: research

Molecular detection of Orientia tsutsugamushi in ectoparasites & amp; their small mammal hosts captured from scrub typhus endemic areas in Madurai district, India
CONCLUSIONS: The outcome of the present investigations widened our scope on the pathogens present in ectoparasites and rodents/shrews from this area. This will help to formulate the required vector control methods to combat zoonotic diseases.PMID:38494626 | DOI:10.4103/ijmr.ijmr_3530_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 18, 2024 Category: Research Authors: R Govindarajan S Gowri Sankar M Senthil Kumar V Rajamannar R Krishnamoorthi A Alwin Prem Anand Ashwani Kumar P Philip Samuel Source Type: research

Low abundance of healthy bacteria in the gastric microbiota can be a potential biomarker for gastrointestinal diseases: A pilot study
Indian J Med Res. 2024 Mar 14. doi: 10.4103/ijmr.ijmr_864_23. Online ahead of print.NO ABSTRACTPMID:38484125 | DOI:10.4103/ijmr.ijmr_864_23 (Source: Indian J Med Res)
Source: Indian J Med Res - March 14, 2024 Category: Research Authors: Safiya Arfi Prateek Sharma Kunal Das Yogendra Bhaskar Isha Goel Harpreet Singh Rajashree Das Source Type: research

Low abundance of healthy bacteria in the gastric microbiota can be a potential biomarker for gastrointestinal diseases: A pilot study
Indian J Med Res. 2024 Mar 14. doi: 10.4103/ijmr.ijmr_864_23. Online ahead of print.NO ABSTRACTPMID:38484125 | DOI:10.4103/ijmr.ijmr_864_23 (Source: Indian J Med Res)
Source: Indian J Med Res - March 14, 2024 Category: Research Authors: Safiya Arfi Prateek Sharma Kunal Das Yogendra Bhaskar Isha Goel Harpreet Singh Rajashree Das Source Type: research

Low abundance of healthy bacteria in the gastric microbiota can be a potential biomarker for gastrointestinal diseases: A pilot study
Indian J Med Res. 2024 Mar 14. doi: 10.4103/ijmr.ijmr_864_23. Online ahead of print.NO ABSTRACTPMID:38484125 | DOI:10.4103/ijmr.ijmr_864_23 (Source: Indian J Med Res)
Source: Indian J Med Res - March 14, 2024 Category: Research Authors: Safiya Arfi Prateek Sharma Kunal Das Yogendra Bhaskar Isha Goel Harpreet Singh Rajashree Das Source Type: research

Evaluation of liver segmental dose threshold for hepatocyte regeneration following liver stereotactic body radiation therapy
CONCLUSIONS: We propose from the findings of this study that in SBRT for large hepatocellular cancer or liver metastases, liver segments should be individually delineated. Furthermore, 3-5 liver segments may be preferentially subjected to <9 Gy to facilitate hepatocyte regeneration. Preferential sparing of uninvolved liver segments may improve outcomes in liver stereotaxyas lower segmental doses were associated with liver regeneration. This may have implications on future liver SBRT planning where segmental doses may be as important as the mean dose.PMID:38442296 | DOI:10.4103/ijmr.ijmr_1171_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 5, 2024 Category: Research Authors: Karishma George Supriya Chopra Karthick Rajamanickam Kishore Joshi Jamema Swamidas Nitin Shetty Reena Engineer Source Type: research

Evaluation of liver segmental dose threshold for hepatocyte regeneration following liver stereotactic body radiation therapy
CONCLUSIONS: We propose from the findings of this study that in SBRT for large hepatocellular cancer or liver metastases, liver segments should be individually delineated. Furthermore, 3-5 liver segments may be preferentially subjected to <9 Gy to facilitate hepatocyte regeneration. Preferential sparing of uninvolved liver segments may improve outcomes in liver stereotaxyas lower segmental doses were associated with liver regeneration. This may have implications on future liver SBRT planning where segmental doses may be as important as the mean dose.PMID:38442296 | DOI:10.4103/ijmr.ijmr_1171_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 5, 2024 Category: Research Authors: Karishma George Supriya Chopra Karthick Rajamanickam Kishore Joshi Jamema Swamidas Nitin Shetty Reena Engineer Source Type: research

Evaluation of liver segmental dose threshold for hepatocyte regeneration following liver stereotactic body radiation therapy
CONCLUSIONS: We propose from the findings of this study that in SBRT for large hepatocellular cancer or liver metastases, liver segments should be individually delineated. Furthermore, 3-5 liver segments may be preferentially subjected to <9 Gy to facilitate hepatocyte regeneration. Preferential sparing of uninvolved liver segments may improve outcomes in liver stereotaxyas lower segmental doses were associated with liver regeneration. This may have implications on future liver SBRT planning where segmental doses may be as important as the mean dose.PMID:38442296 | DOI:10.4103/ijmr.ijmr_1171_21 (Source: Indian J Med Res)
Source: Indian J Med Res - March 5, 2024 Category: Research Authors: Karishma George Supriya Chopra Karthick Rajamanickam Kishore Joshi Jamema Swamidas Nitin Shetty Reena Engineer Source Type: research