A case of disseminated tuberculosis presenting as a metastasizing tumor, complicated by toxic megacolon caused by Clostridium difficile: Difficulties in diagnosis
Magy Seb. 2024 Apr 2;77(1):15-22. doi: 10.1556/1046.2024.10004. Print 2024 Apr 2.ABSTRACTA mára ritkán előforduló tuberkulózis (tbc) extrapulmonális manifesztációi előrehaladott rosszindulatú daganatok képét utánozhatják, jelentős diagnosztikus dilemmákat okozva. A tbc igazolása gyakorta bonyolult, komplex vizsgálatokat igényel. Egy fiatal vietnámi nőbeteg esetét ismertetjük, aki idült hasi fájdalom, fogyás, fejfájás, bal oldali hemiparesis miatt jelentkezett kórházunkban. Az urgens vizsgálatok hasi folyadékgyülemek, lymphadenopathia és peritonealis carcinosis képe mellett az uterushoz as...
Source: Magyar Sebeszet - April 2, 2024 Category: Surgery Authors: G éza Telek Csaba Pol ányi Fanni F ülöp Hai Anh Thu Nguyen Kriszti án Kónya Ilona Bobek Edit Babarczi Ferenc Ender Source Type: research

Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research

A case of disseminated tuberculosis presenting as a metastasizing tumor, complicated by toxic megacolon caused by Clostridium difficile: Difficulties in diagnosis
Magy Seb. 2024 Apr 2;77(1):15-22. doi: 10.1556/1046.2024.10004. Print 2024 Apr 2.ABSTRACTA mára ritkán előforduló tuberkulózis (tbc) extrapulmonális manifesztációi előrehaladott rosszindulatú daganatok képét utánozhatják, jelentős diagnosztikus dilemmákat okozva. A tbc igazolása gyakorta bonyolult, komplex vizsgálatokat igényel. Egy fiatal vietnámi nőbeteg esetét ismertetjük, aki idült hasi fájdalom, fogyás, fejfájás, bal oldali hemiparesis miatt jelentkezett kórházunkban. Az urgens vizsgálatok hasi folyadékgyülemek, lymphadenopathia és peritonealis carcinosis képe mellett az uterushoz as...
Source: Magyar Sebeszet - April 2, 2024 Category: Surgery Authors: G éza Telek Csaba Pol ányi Fanni F ülöp Hai Anh Thu Nguyen Kriszti án Kónya Ilona Bobek Edit Babarczi Ferenc Ender Source Type: research

Pediatric pneumonia - A clinico-pathological study
CONCLUSION: Neither clinical features nor investigations reliably differentiate between viral and bacterial pneumonia. Autopsy has an important role in providing insights into the pathogenesis of pneumonia and suggests inappropriate antibiotic exposure. No prior Indian studies have been performed to compare the clinical and postmortem findings of pneumonia in children.PMID:38563703 | DOI:10.4103/ijpm.ijpm_700_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Pragati A Sathe Monalisa Dash Pradeep Vaideeswar Sunil Karande Lamk Kadiyani Source Type: research

Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research

A case of disseminated tuberculosis presenting as a metastasizing tumor, complicated by toxic megacolon caused by Clostridium difficile: Difficulties in diagnosis
Magy Seb. 2024 Apr 2;77(1):15-22. doi: 10.1556/1046.2024.10004. Print 2024 Apr 2.ABSTRACTA mára ritkán előforduló tuberkulózis (tbc) extrapulmonális manifesztációi előrehaladott rosszindulatú daganatok képét utánozhatják, jelentős diagnosztikus dilemmákat okozva. A tbc igazolása gyakorta bonyolult, komplex vizsgálatokat igényel. Egy fiatal vietnámi nőbeteg esetét ismertetjük, aki idült hasi fájdalom, fogyás, fejfájás, bal oldali hemiparesis miatt jelentkezett kórházunkban. Az urgens vizsgálatok hasi folyadékgyülemek, lymphadenopathia és peritonealis carcinosis képe mellett az uterushoz as...
Source: Magyar Sebeszet - April 2, 2024 Category: Surgery Authors: G éza Telek Csaba Pol ányi Fanni F ülöp Hai Anh Thu Nguyen Kriszti án Kónya Ilona Bobek Edit Babarczi Ferenc Ender Source Type: research

Pediatric pneumonia - A clinico-pathological study
CONCLUSION: Neither clinical features nor investigations reliably differentiate between viral and bacterial pneumonia. Autopsy has an important role in providing insights into the pathogenesis of pneumonia and suggests inappropriate antibiotic exposure. No prior Indian studies have been performed to compare the clinical and postmortem findings of pneumonia in children.PMID:38563703 | DOI:10.4103/ijpm.ijpm_700_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Pragati A Sathe Monalisa Dash Pradeep Vaideeswar Sunil Karande Lamk Kadiyani Source Type: research

Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research

Pediatric pneumonia - A clinico-pathological study
CONCLUSION: Neither clinical features nor investigations reliably differentiate between viral and bacterial pneumonia. Autopsy has an important role in providing insights into the pathogenesis of pneumonia and suggests inappropriate antibiotic exposure. No prior Indian studies have been performed to compare the clinical and postmortem findings of pneumonia in children.PMID:38563703 | DOI:10.4103/ijpm.ijpm_700_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Pragati A Sathe Monalisa Dash Pradeep Vaideeswar Sunil Karande Lamk Kadiyani Source Type: research

A case of disseminated tuberculosis presenting as a metastasizing tumor, complicated by toxic megacolon caused by Clostridium difficile: Difficulties in diagnosis
Magy Seb. 2024 Apr 2;77(1):15-22. doi: 10.1556/1046.2024.10004. Print 2024 Apr 2.ABSTRACTA mára ritkán előforduló tuberkulózis (tbc) extrapulmonális manifesztációi előrehaladott rosszindulatú daganatok képét utánozhatják, jelentős diagnosztikus dilemmákat okozva. A tbc igazolása gyakorta bonyolult, komplex vizsgálatokat igényel. Egy fiatal vietnámi nőbeteg esetét ismertetjük, aki idült hasi fájdalom, fogyás, fejfájás, bal oldali hemiparesis miatt jelentkezett kórházunkban. Az urgens vizsgálatok hasi folyadékgyülemek, lymphadenopathia és peritonealis carcinosis képe mellett az uterushoz as...
Source: Magyar Sebeszet - April 2, 2024 Category: Surgery Authors: G éza Telek Csaba Pol ányi Fanni F ülöp Hai Anh Thu Nguyen Kriszti án Kónya Ilona Bobek Edit Babarczi Ferenc Ender Source Type: research

Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research

High-Dose Isoniazid Lacks EARLY Bactericidal Activity Against Isoniazid-resistant Tuberculosis Mediated by katG Mutations: A Randomized, Phase 2 Clinical Trial
CONCLUSIONS: This study found negligible bactericidal activity of high-dose isoniazid (15-20 mg/kg) in the majority of participants with tuberculosis caused by katG-mutated M.tb. Clinical trial registration available at www.CLINICALTRIALS: gov, ID: NCT01936831.PMID:38564365 | DOI:10.1164/rccm.202311-2004OC (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 2, 2024 Category: Intensive Care Authors: Kamunkhwala Gausi Elisa H Ignatius Veronique De Jager Caryn Upton Soyeon Kim Ashley McKhann Laura Moran Lubbe Wiesner Florian von Groote-Bidlingmaier Philip Marzinek Naadira Vanker Joseph Yvetot Samuel Pierre Susan L Rosenkranz Susan Swindells Andreas H D Source Type: research

High-Dose Isoniazid Lacks EARLY Bactericidal Activity Against Isoniazid-resistant Tuberculosis Mediated by katG Mutations: A Randomized, Phase 2 Clinical Trial
CONCLUSIONS: This study found negligible bactericidal activity of high-dose isoniazid (15-20 mg/kg) in the majority of participants with tuberculosis caused by katG-mutated M.tb. Clinical trial registration available at www.CLINICALTRIALS: gov, ID: NCT01936831.PMID:38564365 | DOI:10.1164/rccm.202311-2004OC (Source: Respiratory Care)
Source: Respiratory Care - April 2, 2024 Category: Respiratory Medicine Authors: Kamunkhwala Gausi Elisa H Ignatius Veronique De Jager Caryn Upton Soyeon Kim Ashley McKhann Laura Moran Lubbe Wiesner Florian von Groote-Bidlingmaier Philip Marzinek Naadira Vanker Joseph Yvetot Samuel Pierre Susan L Rosenkranz Susan Swindells Andreas H D Source Type: research

A case of disseminated tuberculosis presenting as a metastasizing tumor, complicated by toxic megacolon caused by Clostridium difficile: Difficulties in diagnosis
Magy Seb. 2024 Apr 2;77(1):15-22. doi: 10.1556/1046.2024.10004. Print 2024 Apr 2.ABSTRACTA mára ritkán előforduló tuberkulózis (tbc) extrapulmonális manifesztációi előrehaladott rosszindulatú daganatok képét utánozhatják, jelentős diagnosztikus dilemmákat okozva. A tbc igazolása gyakorta bonyolult, komplex vizsgálatokat igényel. Egy fiatal vietnámi nőbeteg esetét ismertetjük, aki idült hasi fájdalom, fogyás, fejfájás, bal oldali hemiparesis miatt jelentkezett kórházunkban. Az urgens vizsgálatok hasi folyadékgyülemek, lymphadenopathia és peritonealis carcinosis képe mellett az uterushoz as...
Source: Magyar Sebeszet - April 2, 2024 Category: Surgery Authors: G éza Telek Csaba Pol ányi Fanni F ülöp Hai Anh Thu Nguyen Kriszti án Kónya Ilona Bobek Edit Babarczi Ferenc Ender Source Type: research

Pediatric pneumonia - A clinico-pathological study
CONCLUSION: Neither clinical features nor investigations reliably differentiate between viral and bacterial pneumonia. Autopsy has an important role in providing insights into the pathogenesis of pneumonia and suggests inappropriate antibiotic exposure. No prior Indian studies have been performed to compare the clinical and postmortem findings of pneumonia in children.PMID:38563703 | DOI:10.4103/ijpm.ijpm_700_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Pragati A Sathe Monalisa Dash Pradeep Vaideeswar Sunil Karande Lamk Kadiyani Source Type: research