Lifetime risk of herpes zoster in the population of Beijing, China
CONCLUSIONS: Given an aging population, HZ poses a significant, growing burden on individuals, the society, and healthcare system of China, highlighting the need for preventative measures such as vaccination.PMID:36968763 | PMC:PMC10031117 | DOI:10.1016/j.puhip.2023.100356 (Source: Herpes)
Source: Herpes - March 27, 2023 Category: Infectious Diseases Authors: Christa Lee Nikolaos Giannelos Desmond Curran Hengjin Dong Haiwen Tang Ning Jiang Chiyu Ye Yanfei Yuan Cheryl Ng Source Type: research
Treatment of a large area perioral viral herpes infection following noninvasive ventilation: A case report
CONCLUSION: Through multidisciplinary consultation, the patient's oral and perioral herpes infection was successfully treated with the following combined approach: (1) Application of topical antviral and antibiotic treatments; (2) keeping the wound moist with a wet wound healing strategy; (3) systemic use of oral antiviral drugs; and (4) symptomatic and nutritional supportive care. The patient was discharged from the hospital after successful wound healing.PMID:36969999 | PMC:PMC10037274 | DOI:10.12998/wjcc.v11.i8.1857 (Source: Herpes)
Source: Herpes - March 27, 2023 Category: Infectious Diseases Authors: A-Mao Tang Jia-Ying Xu Rong Wang Yi-Min Li Source Type: research
Rational Use of Microbiological Tests in the Diagnosis of Central Nervous System Infections Using Restrictive Criteria: a Retrospective Study
This study therefore proposes a simple way to reduce unnecessary microbiological testing in the context of CNS infection suspicion.PMID:36971564 | DOI:10.1128/spectrum.03179-22 (Source: Herpes)
Source: Herpes - March 27, 2023 Category: Infectious Diseases Authors: M T Ngo Nsoga F J P érez-Rodriguez A Mamin A G L'Huillier A Cherkaoui L Kaiser M Schibler Source Type: research
Primary Human Herpes Virus-6 causing recalcitrant pyrexia after pilocytic astrocytoma resection
CONCLUSION: Here, we present the first known case of HHV-6 infection detected by FAME following intracranial tumor resection. We propose a modified algorithm for persistent fever of unknown origin which may decrease symptomatic sequelae, minimize additional procedures, and shorten length of ICU stay.PMID:36966536 | DOI:10.1159/000530114 (Source: Herpes)
Source: Herpes - March 26, 2023 Category: Infectious Diseases Authors: Julie L Chan Peyton Nisson Moise Danielpour Jack Green Source Type: research
Associations between severe and notifiable respiratory infections during the first trimester of pregnancy and congenital anomalies at birth: a register-based cohort study
CONCLUSION: This large population-based study found severe acute respiratory infection in first trimester of pregnancy was associated with a higher risk of selected major cardiovascular anomalies in babies. These findings support measures to prevent acute respiratory infections in pregnant women including through vaccination.PMID:36964492 | PMC:PMC10037767 | DOI:10.1186/s12884-023-05514-8 (Source: Herpes)
Source: Herpes - March 25, 2023 Category: Infectious Diseases Authors: Abrar A Chughtai Wen-Qiang He Bette Liu Source Type: research
Viral- and tumor-reactive natural killer cells
Semin Immunol. 2023 Mar 23;67:101749. doi: 10.1016/j.smim.2023.101749. Online ahead of print.ABSTRACTWhen we can understand what natural killer (NK) cells recognize during an encounter with an infectious pathogen or a tumor cell, and when we can understand how the NK cell responds to that encounter, we can then begin to understand the role of NK cells in human health and how to improve upon their role for the prevention and treatment of human disease. In the quest to understand how these cells function in antiviral and antitumoral immunity, there have been previously described mechanisms established for NK cells to partici...
Source: Herpes - March 25, 2023 Category: Infectious Diseases Authors: Jianhua Yu Michael A Caligiuri Source Type: research
Fusion peptide is superior to co-expressing subunits for arming oncolytic herpes virus with interleukin 12
CONCLUSIONS: The results implicate that a fusion-type expression of IL-12 is a method superior to co-expression of separate subunits, due to higher production of functional IL-12 molecules. This study led to the creation of triple-mutated oncolytic HSV-1 armed with human IL-12 currently used in phase 1/2 trial for malignant melanoma.PMID:36966232 | PMC:PMC10039936 | DOI:10.1038/s43856-023-00270-4 (Source: Herpes)
Source: Herpes - March 25, 2023 Category: Infectious Diseases Authors: Hiroshi Fukuhara Yuzuri Tsurumaki Sato Jiangang Hou Miwako Iwai Tomoki Todo Source Type: research
Associations between severe and notifiable respiratory infections during the first trimester of pregnancy and congenital anomalies at birth: a register-based cohort study
CONCLUSION: This large population-based study found severe acute respiratory infection in first trimester of pregnancy was associated with a higher risk of selected major cardiovascular anomalies in babies. These findings support measures to prevent acute respiratory infections in pregnant women including through vaccination.PMID:36964492 | DOI:10.1186/s12884-023-05514-8 (Source: Herpes)
Source: Herpes - March 25, 2023 Category: Infectious Diseases Authors: Abrar A Chughtai Wen-Qiang He Bette Liu Source Type: research
Viral- and tumor-reactive natural killer cells
Semin Immunol. 2023 Mar 23;67:101749. doi: 10.1016/j.smim.2023.101749. Online ahead of print.ABSTRACTWhen we can understand what natural killer (NK) cells recognize during an encounter with an infectious pathogen or a tumor cell, and when we can understand how the NK cell responds to that encounter, we can then begin to understand the role of NK cells in human health and how to improve upon their role for the prevention and treatment of human disease. In the quest to understand how these cells function in antiviral and antitumoral immunity, there have been previously described mechanisms established for NK cells to partici...
Source: Herpes - March 25, 2023 Category: Infectious Diseases Authors: Jianhua Yu Michael A Caligiuri Source Type: research
Fusion peptide is superior to co-expressing subunits for arming oncolytic herpes virus with interleukin 12
CONCLUSIONS: The results implicate that a fusion-type expression of IL-12 is a method superior to co-expression of separate subunits, due to higher production of functional IL-12 molecules. This study led to the creation of triple-mutated oncolytic HSV-1 armed with human IL-12 currently used in phase 1/2 trial for malignant melanoma.PMID:36966232 | DOI:10.1038/s43856-023-00270-4 (Source: Herpes)
Source: Herpes - March 25, 2023 Category: Infectious Diseases Authors: Hiroshi Fukuhara Yuzuri Tsurumaki Sato Jiangang Hou Miwako Iwai Tomoki Todo Source Type: research
Design, synthesis, antiviral activities of ferulic acid derivatives
Front Pharmacol. 2023 Mar 3;14:1133655. doi: 10.3389/fphar.2023.1133655. eCollection 2023.ABSTRACTA series of novel ferulic acid derivatives were designed and synthesized, and the twenty-one compounds were evaluated for their antiviral activities against Respiratory syncytial virus (RSV), herpes simplex virus type 1 (HSV-1), and enterovirus type 71 (EV71). These derivatives with the core structure of diphenyl acrylic acids had cis-trans isomers, which were confirmed by 1H NMR, HPLC, and UV-vis spectra for the first time. The A5 had a selective effect against RSV but no work on herpes simplex virus type 1 and enterovirus ty...
Source: Herpes - March 24, 2023 Category: Infectious Diseases Authors: Jin-Long Mao Lei Wang Shu-Jie Chen Bin Yan Li-Ying Xun Rui-Cheng Li Pei-Chen Wang Qi-Tao Zhao Source Type: research
The incidence of infection in tumor and eye fluid system, and specific humoral immunity to herpes viruses in patients with uveal melanoma
CONCLUSION: Our findings suggest the possible participation of EBV in the oncogenesis of the uveal tract and emphasize the need for further in-depth study of this problem.PMID:36961234 | DOI:10.36233/0507-4088-154 (Source: Herpes)
Source: Herpes - March 24, 2023 Category: Infectious Diseases Authors: E V Svetlova N V Balatskaya S V Saakyan A A Zharov G I Krichevskaya I V Svirina N S Izmailova E B Myakoshina Source Type: research
Fluorothymidine PET/CT Identifies a Case of Herpes Simplex Virus Esophagitis
Radiol Imaging Cancer. 2023 Mar;5(2):e220141. doi: 10.1148/rycan.220141.NO ABSTRACTPMID:36961315 | DOI:10.1148/rycan.220141 (Source: Herpes)
Source: Herpes - March 24, 2023 Category: Infectious Diseases Authors: Joshua Glover Ajay Nadig Sara Vesely Deepika Neelakantan Kirsten M Williams Jennifer Holter-Chakrabarty Source Type: research
Practice trends in pediatric sudden sensorineural hearing loss management: An unresolved diagnosis
CONCLUSIONS: Most pediatric otolaryngologists treat SSNHL with systemic steroids. The remainder of the diagnostic and management paradigm varies significantly, highlighting the need to systematically define which treatment optimizes outcomes in this population.PMID:36963235 | DOI:10.1016/j.amjoto.2023.103845 (Source: Herpes)
Source: Herpes - March 24, 2023 Category: Infectious Diseases Authors: Kimberly Luu Amber D Shaffer David H Chi Source Type: research
Immunoregulatory actions of calf thymus extract (TFX ®) in vitro in relation to its effect on expression of mitogen activated protein kinases
Int Immunopharmacol. 2023 Mar 22;118:109995. doi: 10.1016/j.intimp.2023.109995. Online ahead of print.ABSTRACTThe in vitro immunotropic actions of a calf thymus extract - thymus factor X (TFX®) preparation were investigated. The preparation did not lower the viability of the A549 epithelial cell line and mouse bone marrow cells in the investigated concentration range. TFX® exhibited a co-stimulatory action of concanavalin A (Con A)-induced mouse thymocyte proliferation and partially restored the mitogen-induced proliferation capability of mouse thymocytes exposed to hydrocortisone (HC). The preparation also inhibited Her...
Source: Herpes - March 24, 2023 Category: Infectious Diseases Authors: Micha ł Zimecki Iwona Kochanowska Ewa Zaczy ńska Maja Koci ęba Jolanta Artym Aleksandra Zambrowicz Magdalena Matwiejczyk Monika Besman Karol Kuchar Aleksander Skotnicki Source Type: research
