Association between COVID-19 and angiotensin-converting enzyme inhibitors with the spotlight on zinc: an opinion
Ann Med. 2021 Dec;53(1):1673-1675. doi: 10.1080/07853890.2021.1981545.ABSTRACTIn the setting of the raging COVID-19 pandemic, the search for innovative therapeutics is desperately sought after. As we learn more about the characteristics and metabolic health of patients and as our understanding of COVID-19 pathophysiology and treatment progresses, so is our understanding of medication effects that might increase disease severity. As of late, ACE inhibitors have been under investigation for a potential increase in illness severity due to ACE2 upregulation. Given our knowledge of other nutrient-pharmaceutical interactions, co...
Source: Annals of Medicine - September 24, 2021 Category: Internal Medicine Authors: Bashar Khiatah Amylee Amos Deborah Carlson Source Type: research

Protective effect of standardised fruit extract of < em > Garcinia cowa < /em > Roxb. ex Choisy against ethanol induced gastric mucosal lesions in Wistar rats
CONCLUSIONS: Oral administration of GCE at doses of 200 and 400 mg/kg exhibited significant (p
Source: Annals of Medicine - September 24, 2021 Category: Internal Medicine Authors: Prakash Chandra Gupta Ashish Kar Nisha Sharma Prashant Kumar Singh Naba Kumar Goswami Satyanshu Kumar Source Type: research

Infective endocarditis secondary to coagulase-negative staphylococcus revealed by endogenous endophthalmitis: Case report
CONCLUSION: Endogenous endophthalmitis remains an emergency. The search for a source of infection, primarily endocarditis, is systematic. The improvement of the prognosis depends essentially on the eviction and early treatment of infectious foci in people at risk.PMID:34557297 | PMC:PMC8445831 | DOI:10.1016/j.amsu.2021.102788 (Source: Annals of Medicine)
Source: Annals of Medicine - September 24, 2021 Category: Internal Medicine Authors: Hanane Choukrani Anass Maaroufi Boutar Ould Mohamed Sidi Mohamed Ghali Bennouna Abdennasser Drighil Rachida Habbal Source Type: research

Newly acquired factor VIII deficiency in a male Ex-smoker - A case report
CONCLUSION: A key point to successfully treating AHA is to remove inhibitors and stop bleeding. Mortality in patients presenting with AHA is related to the bleeding and hemorrhage, therefore rapid diagnosis and effective treatment are needed.PMID:34557298 | PMC:PMC8445843 | DOI:10.1016/j.amsu.2021.102830 (Source: Annals of Medicine)
Source: Annals of Medicine - September 24, 2021 Category: Internal Medicine Authors: Pratishtha Singh Brian Gorman Nardine Abdelsayed Mohamed Faris Source Type: research

Antimalarials may reduce cancer risk in patients with systemic lupus erythematosus: a systematic review and meta-analysis of prospective studies
CONCLUSION: Results of this meta-analysis showed that antimalarial drugs might be protective factors for cancer in SLE. Hydroxychloroquine might be a protective factor for cancer in SLE patients.KEY MESSAGESAntimalarials might be protective factors for cancer in SLE.Hydroxychloroquine might be a protective factor for cancer in SLE patients.The first article to perform the meta-analysis of antimalarial drugs on the risk of cancer in SLE patients.PMID:34553648 | DOI:10.1080/07853890.2021.1981547 (Source: Annals of Medicine)
Source: Annals of Medicine - September 23, 2021 Category: Internal Medicine Authors: Xian-Bao Li Nv-Wei Cao Xiu-Jie Chu Hao-Yue Zhou Hua Wang Si-Jie Yu Dong-Qing Ye Bao-Zhu Li Source Type: research

Medical students and risk of COVID-19 infection: A descriptive cross-sectional study from the university of Jordan
CONCLUSION: The incidence of positive COVID-19 tests was found to be higher among clinical students as compared to pre-clinical students. Commitment to general health safety precautions did not appear to be protective enough for clinical students. It is fundamental that additional strategies, including access to vaccines, are set, and deficiencies in current protections are identified to maintain students' safety and well-being.PMID:34545306 | PMC:PMC8444353 | DOI:10.1016/j.amsu.2021.102775 (Source: Annals of Medicine)
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Amjad Bani Hani Nader Alaridah Mahmoud Abu Abeeleh Amjad Shatarat Rama Rayyan Amer Kamal Laila Alhafez Rasha Odeh Raed Nael Al-Taher Source Type: research

The utilization of hydroxychloroquine to reduce the main signs and symptoms of COVID-19 patients, a cross-sectional study
Ann Med Surg (Lond). 2021 Sep 16:102867. doi: 10.1016/j.amsu.2021.102867. Online ahead of print.ABSTRACTHydroxychloroquine and chloroquine were found to have positive results in some non-randomized clinical trials with more benefit in decreasing the viral load of COVID-19. Hydroxychloroquine (HCQ) is a lysosomotropic and lipophilic drug that can penetrate cell membranes, which accumulates in the acidic lysosomes. The high concentration of alkaline HCQ increases the pH in lysosomes from the normal levels of 4.7-4.8 to 6 which leads to inhibition of lysosomes functions and thus, prevents the entry of coronavirus into cells.O...
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Salem Alsuwaidan Ziad A Memish Faisal Alaklobi Kholood Khan Hamdan N Alajami Source Type: research

Dexamethasone or methylprednisolone therapy in covid-19 pneumonia: A retrospective and comparative study of 513 cases
CONCLUSION: Both steroids are efficient in the management of mild, moderate and severe Covid-19 pneumonia with a clear superiority of dexamethasone especially in severe forms.PMID:34545308 | PMC:PMC8437702 | DOI:10.1016/j.amsu.2021.102858 (Source: Annals of Medicine)
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Sanae El Mezzeoui Ghizlane El Aidouni Manal Merbouh Abderrahim El Kaouini Fatima Zahra Aftiss Samia Berrichi Sara Berrajaa Houssam Bkiyer Naima Abda Brahim Housni Source Type: research

Medical students and risk of COVID-19 infection: A descriptive cross-sectional study from the university of Jordan
CONCLUSION: The incidence of positive COVID-19 tests was found to be higher among clinical students as compared to pre-clinical students. Commitment to general health safety precautions did not appear to be protective enough for clinical students. It is fundamental that additional strategies, including access to vaccines, are set, and deficiencies in current protections are identified to maintain students' safety and well-being.PMID:34545306 | PMC:PMC8444353 | DOI:10.1016/j.amsu.2021.102775 (Source: Annals of Medicine)
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Amjad Bani Hani Nader Alaridah Mahmoud Abu Abeeleh Amjad Shatarat Rama Rayyan Amer Kamal Laila Alhafez Rasha Odeh Raed Nael Al-Taher Source Type: research

The utilization of hydroxychloroquine to reduce the main signs and symptoms of COVID-19 patients, a cross-sectional study
Ann Med Surg (Lond). 2021 Sep 16:102867. doi: 10.1016/j.amsu.2021.102867. Online ahead of print.ABSTRACTHydroxychloroquine and chloroquine were found to have positive results in some non-randomized clinical trials with more benefit in decreasing the viral load of COVID-19. Hydroxychloroquine (HCQ) is a lysosomotropic and lipophilic drug that can penetrate cell membranes, which accumulates in the acidic lysosomes. The high concentration of alkaline HCQ increases the pH in lysosomes from the normal levels of 4.7-4.8 to 6 which leads to inhibition of lysosomes functions and thus, prevents the entry of coronavirus into cells.O...
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Salem Alsuwaidan Ziad A Memish Faisal Alaklobi Kholood Khan Hamdan N Alajami Source Type: research

Dexamethasone or methylprednisolone therapy in covid-19 pneumonia: A retrospective and comparative study of 513 cases
CONCLUSION: Both steroids are efficient in the management of mild, moderate and severe Covid-19 pneumonia with a clear superiority of dexamethasone especially in severe forms.PMID:34545308 | PMC:PMC8437702 | DOI:10.1016/j.amsu.2021.102858 (Source: Annals of Medicine)
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Sanae El Mezzeoui Ghizlane El Aidouni Manal Merbouh Abderrahim El Kaouini Fatima Zahra Aftiss Samia Berrichi Sara Berrajaa Houssam Bkiyer Naima Abda Brahim Housni Source Type: research

Medical students and risk of COVID-19 infection: A descriptive cross-sectional study from the university of Jordan
CONCLUSION: The incidence of positive COVID-19 tests was found to be higher among clinical students as compared to pre-clinical students. Commitment to general health safety precautions did not appear to be protective enough for clinical students. It is fundamental that additional strategies, including access to vaccines, are set, and deficiencies in current protections are identified to maintain students' safety and well-being.PMID:34545306 | PMC:PMC8444353 | DOI:10.1016/j.amsu.2021.102775 (Source: Annals of Medicine)
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Amjad Bani Hani Nader Alaridah Mahmoud Abu Abeeleh Amjad Shatarat Rama Rayyan Amer Kamal Laila Alhafez Rasha Odeh Raed Nael Al-Taher Source Type: research

The utilization of hydroxychloroquine to reduce the main signs and symptoms of COVID-19 patients, a cross-sectional study
Ann Med Surg (Lond). 2021 Sep 16:102867. doi: 10.1016/j.amsu.2021.102867. Online ahead of print.ABSTRACTHydroxychloroquine and chloroquine were found to have positive results in some non-randomized clinical trials with more benefit in decreasing the viral load of COVID-19. Hydroxychloroquine (HCQ) is a lysosomotropic and lipophilic drug that can penetrate cell membranes, which accumulates in the acidic lysosomes. The high concentration of alkaline HCQ increases the pH in lysosomes from the normal levels of 4.7-4.8 to 6 which leads to inhibition of lysosomes functions and thus, prevents the entry of coronavirus into cells.O...
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Salem Alsuwaidan Ziad A Memish Faisal Alaklobi Kholood Khan Hamdan N Alajami Source Type: research

Dexamethasone or methylprednisolone therapy in covid-19 pneumonia: A retrospective and comparative study of 513 cases
CONCLUSION: Both steroids are efficient in the management of mild, moderate and severe Covid-19 pneumonia with a clear superiority of dexamethasone especially in severe forms.PMID:34545308 | PMC:PMC8437702 | DOI:10.1016/j.amsu.2021.102858 (Source: Annals of Medicine)
Source: Annals of Medicine - September 21, 2021 Category: Internal Medicine Authors: Sanae El Mezzeoui Ghizlane El Aidouni Manal Merbouh Abderrahim El Kaouini Fatima Zahra Aftiss Samia Berrichi Sara Berrajaa Houssam Bkiyer Naima Abda Brahim Housni Source Type: research

Post-herniorrhaphy extubation technique in pediatric patient with congenital diaphragmatic hernia and VACTERL association: A case report
CONCLUSION: This case report illustrates extubation technique in a post-herniorrhaphy patient with congenital diaphragmatic hernia and VACTERL association. Moreover, several options of extubation techniques can be used for extubation procedure in pediatric patient with CDH.PMID:34540207 | PMC:PMC8437770 | DOI:10.1016/j.amsu.2021.102801 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Diajeng Putri Iracily Desy Rusmawatiningtyas Firdian Makrufardi Intan Fatah Kumara None Nurnaningsih Edy Moeljono Source Type: research

A case report of patellar fracture treated by percutaneous strong suture technique
We report a case of patellar fracture treated with a minimally invasive percutaneous strong suture. The patient is a 57-year-old salesman who fell at work, hit his knee, and came to our hospital complaining of pain. His range of motion was -15° in extension and 60° in flexion. His X-ray results showed a transverse fracture of the right patella with a 3-mm displacement, and surgery was performed 7 days post-injury. A small incision of 1 cm was made distally and proximally on the patella. Two 2.0-mm perforated K-wires were inserted from distal to proximal sides, and the wire was pulled out proximally with FiberWire&r...
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Shinnosuke Hada Muneaki Ishijima Yoshimasa Tomita Source Type: research

Applying digital storytelling in the medical oncology curriculum: Effects on students' achievement and critical thinking
CONCLUSIONS: The study demonstrated that DST promoted CT. We recommend the use of DST to promote CT in clinical education placements.PMID:34540209 | PMC:PMC8441090 | DOI:10.1016/j.amsu.2021.102528 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Afagh Zarei Rita Mojtahedzadeh Aeen Mohammadi John Sandars Seyed Amir Hossein Emami Source Type: research

Hyperleukocytosis-induced stroke and tonsillar herniation: Case report
CONCLUSION: This case demonstrate the value of early recognition and prompt management of posterior circulation ischemic stroke in children with leukemia and hyperleukocytosis at presentation.PMID:34540210 | PMC:PMC8441068 | DOI:10.1016/j.amsu.2021.102776 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Hasan Hashem Baha'eddin A Muhsen Source Type: research

Prevalence and risk factors of psychoactive substance abuse among students in Ethiopia: A systematic review and meta-analysis
CONCLUSION: The review revealed that one-third of the high school and higher education students used different psychoactive substances in Ethiopia.REGISTRATION: This Systematic Review and Meta-Analysis was registered in Prospero international prospective register of systemic reviews (CRD42020146656) on April 28/2020.PMID:34540211 | PMC:PMC8437783 | DOI:10.1016/j.amsu.2021.102790 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Semagn Mekonnen Abate Yigrem Ali Chekol Solomon Yimer Minaye Source Type: research

A blistering new era for bullous pemphigoid: A scoping review of current therapies, ongoing clinical trials, and future directions
Ann Med Surg (Lond). 2021 Sep 4;70:102799. doi: 10.1016/j.amsu.2021.102799. eCollection 2021 Oct.ABSTRACTBullous pemphigoid (BP) is a severe autoimmune blistering skin disorder that primarily causes disease in the older population and is the most prevalent subepidermal variant of the pemphigoid diseases. It manifests as exquisitely pruritic vesiculobullous eruptions and is associated with significant morbidity and mortality. Studies are reporting an increase in prevalence, and, among the elderly, BP is no longer considered to be as rare as previously thought. The pathogenesis involves autoantibodies directed against protei...
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Subaina Naeem Khalid Zeest Ali Khan Muhammad Hamza Ali Talal Almas Tarek Khedro Vikneswaran Raj Nagarajan Source Type: research

Partial replacement of pelvis with the hip joint in osteosarcoma treatment: A case report
CONCLUSION: Using customized 3D-printed prosthesis is a good way for management of pelvic osteosarcoma.PMID:34540213 | PMC:PMC8435817 | DOI:10.1016/j.amsu.2021.102812 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Dung Tran Trung Sang Nguyen Tran Quang Hieu Pham Trung Nam Vu Tu Nang Vo Sy Quyen Thanh Tran Duc Nguyen Tien Dung Tran Thiet Son Pham Thi Viet Dung Nguyen Van Truong Source Type: research

Biliary infection; distribution of species and antibiogram study
CONCLUSION: Cephalosporins as an empirical treatment for biliary infections is not suitable. Aminoglycosides including amikacin and gentamycin are costly beneficial as the first line for empirical antibiotic therapy in selected patients because of their good bacterial sensitivity and low expenses. Imipenem should remain for multidrug resistance species.PMID:34540214 | PMC:PMC8435813 | DOI:10.1016/j.amsu.2021.102822 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Shima Shafagh Seyed Hamed Rohani Abbas Hajian Source Type: research

Optical coherence tomography angiography features of macular neovascularization in wet age-related macular degeneration: A cross-sectional study
CONCLUSION: OCT-A is a non-invasive, safe, and reproducible retinal imaging technique with a high sensitivity of detection of MNV in AMD. It provides useful qualitative and quantitative data. The involvement of OCT-A in the treatment decision for MNV in AMD is linked to identifying the "pattern" of the lesion reflecting its active or inactive status.PMID:34540215 | PMC:PMC8435926 | DOI:10.1016/j.amsu.2021.102826 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Mahjoub Ahmed Ben Mrad Syrine Ben Abdesslem Nadia Mahjoub Anis Zinelabidine Karim Ghorbel Mohamed Mahjoub Hachemi Krifa Fethi Knani Leila Source Type: research

"Childrens are not just "little adults". The rate of medication related problems and its predictors among patients admitted to pediatric ward of southwestern Ethiopian hospital: A prospective observational study
Ann Med Surg (Lond). 2021 Sep 7;70:102827. doi: 10.1016/j.amsu.2021.102827. eCollection 2021 Oct.ABSTRACTBACKGROUND: The rate of medication related problems is high in developing countries due to the complexity of pediatrics medication management. Pediatric population should have their own dosage regimens. The pediatric dosage regimens were derived from the adult dose that might lead to sudden reach of sub or supra-therapeutic doses. As the result, the medication therapy management is difficult in this populations. Despite this, a scanty of studies were conducted on medication related problems among pediatric populations. ...
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Firomsa Bekele Gudisa Bereda Lalisa Tamirat Bonsa Amsalu Geleta Dabala Jabessa Source Type: research

The effect of stone and patient characteristics in predicting extra-corporal shock wave lithotripsy success rate: A cross sectional study
CONCLUSIONS: This study shows that determination of stone density and stone size on CT KUB pre ESWL can help to predict the outcome of ESWL. We propose that stone density
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Mohammad Al-Zubi Ammar Al Sleibi Basel Mazen Elayan Subhi Zahi Al-Issawi Morad Bani-Hani Adel Alsharei Jad AlSmadi Saleh Abualhaj Ala' Y Ibrahim Source Type: research

Incidence of secondary rupture after abdominal aortic aneurysms (endovascular vs. open surgical repair)
Ann Med Surg (Lond). 2021 Sep 9;70:102831. doi: 10.1016/j.amsu.2021.102831. eCollection 2021 Oct.ABSTRACTA best evidence topic has been constructed using a described protocol. The three-part question addressed was: In patients with Infrarenal abdominal aortic aneurysm (AAA), Does endovascular abdominal aortic repair (EVAR), AS compared to open surgical repair (OSR), has lower secondary rupture rates? The outcomes assessed were the secondary rupture rate in both techniques. The best evidence showed that The OSR has statistically significant lower secondary rupture rates than the EVAR.PMID:34540218 | PMC:PMC8435911 | DOI:10....
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Ahmed Abdel Rahim Rashid Ibrahim Lu Yao Ahmed Khalf Mohammed Ismail Source Type: research

Vitiligo and pregnancy: How do each affect the other?
Ann Med Surg (Lond). 2021 Sep 8;70:102833. doi: 10.1016/j.amsu.2021.102833. eCollection 2021 Oct.ABSTRACTVitiligo is one of the dermatomes affecting the melanocytes resulting in their destruction and subsequent patchy depigmentation of the skin. It is postulated to occur due to an autoimmune problem. Despite being a disease with limited systemic involvement and lack of mortality, it has a severe psychological impact. It may have a powerfully negative effect on a patient's quality of life. The relationship between vitiligo and pregnancy is not widely acknowledged. It may be associated with adverse pregnancy outcomes such as...
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Mohsen M A Abdelhafez Karim A M Ahmed Nicholas Tze Ping Pang Dg Marshita Pg Baharuddin Win Win Than Fairrul Kadir Mohammad Saffree Jeffree Firdaus Hayati Source Type: research

A challenging diagnosis and management of Herlyn-Werner-Wunderlich Syndrome in low-resource Settings: A case report complicated with hydronephrosis
CONCLUSION: although MRI is the gold standard for establishing the diagnosis and preoperative planning, ultrasound and CT scan can be an alternative, less expensive, and reliable approach. In addition, Laparoscopy or vaginoscopy may not be available in these countries. Therefore, correcting the anomalies can be achieved with laparotomy, which results in acceptable outcomes without any complications.PMID:34540220 | PMC:PMC8437768 | DOI:10.1016/j.amsu.2021.102843 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Sami Jomaa Kenana Tawashi Fatima Alzhraa All Rass Eyad Abdallah Nazih Tawashi Source Type: research

Association of soluble ST2 and infarct location within 12-24  h in STEMI: A cross-sectional study
CONCLUSION: sST2 was not associated with infarct location within 12-24 h onset of STEMI. This results suggest that infarct location might not responsible for the elevation of serum sST2 levels in acute phase of STEMI.PMID:34540221 | PMC:PMC8435924 | DOI:10.1016/j.amsu.2021.102844 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Sem David Timothy Anggoro Budi Hartopo Vita Yanti Anggraeni Firdian Makrufardi Source Type: research

Rapid severe sepsis from < em > Pseudomonas fluorescens/putida < /em > bacteremia due to skin and soft tissue infection - A case report
CONCLUSION: Our case highlights an immunocompetent patient with rapid progressive sepsis and associated multisystem organ failure. We emphasize the importance of early recognition in these patients and treatment with appropriate antimicrobial therapy followed by source control.PMID:34540222 | PMC:PMC8437775 | DOI:10.1016/j.amsu.2021.102845 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Pratishtha Singh Andreas Montano Adam Bostick Source Type: research

Formation of the upper gastrointestinal tract for patients who underwent total esophago-gastrectomy due to caustic ingestion: Case series
CONCLUSIONS: The ileum-right colon segment is a part that can be used to reconstruct the upper gastrointestinal tract following esophago-gastrectomy.PMID:34540223 | PMC:PMC8435914 | DOI:10.1016/j.amsu.2021.102846 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Tran Manh Hung Thi Phuong Thao Tran Nguyen Trung Kien Tran Thi Phuong Source Type: research

Fungal burn wound infection caused by < em > Fusarium dimerum < /em > : A case series on a rare etiology
CONCLUSION: Considering the sparse literature that is available regarding Fusarium infection in burn victims, this study aims to improve the knowledge surrounding different facets of this disease including its epidemiology, diagnosis, management, and the need to maintain high suspicion of this fungal disease in burn patients.PMID:34540224 | PMC:PMC8435921 | DOI:10.1016/j.amsu.2021.102848 (Source: Annals of Medicine)
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Subaina Naeem Khalid Nousheen Rizwan Zeest Ali Khan Ali Najam Amin Moazzam Khan Talal Almas Tarek Khedro Vikneswaran Raj Nagarajan Abdulaziz Alshamlan Amin Gronfula Rahaf Alshehri Source Type: research

Concerns and reflections on the second wave of COVID-19 in Argentina: A perspective by general surgery residents
Ann Med Surg (Lond). 2021 Oct;70:102860. doi: 10.1016/j.amsu.2021.102860. Epub 2021 Sep 14.ABSTRACTIn Argentina, the second wave of COVID-19, which started in May, clearly differentiates us from the rest of the Latin American countries, whose current growth may be the announcement of the expected autumn-winter expansion. There is a lot of uncertainty about how the pandemic will evolve, which contrasts with the expectations that had been generated in society after the end of the confinement, both of the control of the health system and access to effective vaccines. Thus, a group of surgeons in training raised a series of co...
Source: Annals of Medicine - September 20, 2021 Category: Internal Medicine Authors: Ren é M Palacios Huatuco Julian E Lia ño Gonzalo M Bono Gabriel A Gonz ález Vargas Lucas Panichelli Rafael Pereyra Ferrero Mar ía S Ponce Beti Source Type: research

Influence of changes in body fat on clinical outcomes in a general population: a 12-year follow-up report on the Ansan-Ansung cohort in the Korean Genome Environment Study
Ann Med. 2021 Dec;53(1):1646-1658. doi: 10.1080/07853890.2021.1976416.ABSTRACTBACKGROUND: The impact of the changes in the obesity status on mortality has not been established; thus, we investigated the long-term influence of body fat (BF) changes on all-cause deaths and cardiovascular outcomes in a general population.METHODS: A total of 8374 participants were observed for 12 years. BF was measured at least two times using a bioimpedance method. The causes of death were acquired from the nationwide database. A major adverse cardiovascular event (MACE) was defined as a composite of myocardial infarction, coronary artery dis...
Source: Annals of Medicine - September 17, 2021 Category: Internal Medicine Authors: Byung Sik Kim Yonggu Lee Hyun-Jin Kim Jeong-Hun Shin Jin-Kyu Park Hwan-Cheol Park Young-Hyo Lim Jinho Shin Source Type: research

Another lost tribe: Quantifying the experience of international medical graduates applying for a national training number (NTN) in the United Kingdom with a cross-sectional study
CONCLUSION: Obtaining an NTN remains a crucial goal among IMGs in the UK, despite the obstacles and repeated failures in doing so.PMID:34527230 | PMC:PMC8433111 | DOI:10.1016/j.amsu.2021.102665 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Islam Noaman Adeel Abbas Dhahri Elsamoual Mohammed Source Type: research

Transfer factor treatment in management of peritonitis condition: An experimental study in rat
CONCLUSIONS: Transfer factors increased the phagocytic activity of macrophages in a Wistar rat model of peritonitis. This suggests that transfer factors could have a role as an immunomodulatory treatment for peritonitis.PMID:34527231 | PMC:PMC8433118 | DOI:10.1016/j.amsu.2021.102755 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Tommy Rubiyanto Habar Andi Asadul Islam Mochammad Hatta None Warsinggih Ahmad Mahmudi Muhammad Nasrum Massi Agussalim Bukhari Dikki Drajat Kusmayadi Rizki Diposarosa Asrul Mappiwali Source Type: research

Cervical spine dislocation on ankylosing spondylitis: A case report
Ann Med Surg (Lond). 2021 Sep 4;69:102766. doi: 10.1016/j.amsu.2021.102766. eCollection 2021 Sep.ABSTRACTTreatment of cervical spine fracture in patients with ankylosing spondylitis is difficult. Biomechanical changes related to ossified ankylosing spondylitis spine make cervical spine fractures highly unstable. They cover the entire width of the spine inducing. multidirectional instability and the risk of neurological injuries. Treatment is more difficult that in the nonossified spine. Different treatments have been proposed including anterior stabilization, posterior stabilization, or both. This paper present a case of a...
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Tarik Mesbahi Marouane Makhchoune Reda Mouine Abederrahmane Rafiq Abdelhakim Lakhdar Source Type: research

Hybrid management of aneurysmal vascular ring and a Kommerell's diverticulum in an adult: Case report
CONCLUSION: A multidisciplinary team effort is key. Hybrid management of aneurysmal congenital vascular rings in high risk adults offers an attractive management alternative to conventional surgery.PMID:34527233 | PMC:PMC8433116 | DOI:10.1016/j.amsu.2021.102778 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Dambuza Nyamande Siphosenkosi M Mazibuko Source Type: research

Characterization of Crohn's disease patients in Egypt: Risk factors for postoperative recurrence (A cohort study)
CONCLUSIONS: Age at diagnosis, age at operation, ileal location of Crohn's disease can significantly predict postoperative recurrence. Also, postoperative biological therapy can significantly decrease the incidence of postoperative recurrence.PMID:34527234 | PMC:PMC8430268 | DOI:10.1016/j.amsu.2021.102781 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Shimaa Kamel Mohamed Sakr Waleed Hamed Mohamed Eltabbakh Ahmed Sherief Heba Rashad Yasser Elghamrini Ahmed Elbaz Source Type: research

Ectoparasitosis, a rare cause of severe iron deficiency anemia: A case report
Ann Med Surg (Lond). 2021 Sep 6;69:102784. doi: 10.1016/j.amsu.2021.102784. eCollection 2021 Sep.ABSTRACTPediculosis is a common condition caused by an infestation of head and body louse (ectoparasites) and remains a public health concern. Generally, infestation presents as pruritus in children and has a benign course, but there have been a handful of cases reported in the literature describing severe iron deficiency anemia (IDA) in high-risk groups such as children, history of psychiatric disorder including depression, and low socioeconomic status. Though an uncommonly encountered etiology of anemia, the aim of this case ...
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Nuzhat Batool David Song Jonathan Vincent M Reyes Saad Ahmad Arigirios Skulkidis Talal Almas Tarek Khedro Maritza Brown Source Type: research

Living with someone else's penis: The lived experiences of two South African penile allograft recipients: A descriptive phenomenological study
CONCLUSION: This study emphasises the necessity of offering penile transplantation as treatment for penile loss as this is not only life enhancing but lifesaving, especially within the South African context.PMID:34527236 | PMC:PMC8430241 | DOI:10.1016/j.amsu.2021.102794 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Andr é van der Merwe Yoesrie Toefy Mohammed Rafique Moosa Heidi van Deventer Chantelle J Scott Source Type: research

A rare occurrence of psoas abscess with uterine didelphys and renal agenesis: A case report
CONCLUSION: This case highlights the possibility of psoas abscess as a primary presentation of Mullerian duct anomaly. Further, a differential of uterine didelphys should be considered in every reproductive age female presenting with recurrent pelvic infection.PMID:34527237 | PMC:PMC8429909 | DOI:10.1016/j.amsu.2021.102802 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Sujit Kumar Mandal Shreeja Shikhrakar Binit Upadhaya Regmi Shiba Bam Source Type: research

Incidental finding of congenital pericardial defect during vats bullectomy. Tips and tricks to avoid blunder
In conclusion, no surgical intervention is required in cases of congenital pericardial defect, unless the patient is symptomatic due to complications. If detected incidentally during cardiac or thoracic surgery, the best may be to leave it alone.PMID:34527238 | PMC:PMC8429913 | DOI:10.1016/j.amsu.2021.102806 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Guo Hou Loo Hafiz Ismail Muhammad Ishamuddin Ismail Nur Ayub Bin Md Ali Mohd Ramzisham Bin Abdul Rahman Hairulfaizi Haron Source Type: research

Myasthenia gravis in an old woman discovered during sedation for diagnostic digestive fibroscopy: Case report
Conclusion: Myasthenia can occur in perioperative settings outside the usual circumstances. The prognosis depends on early and adapted management.PMID:34527239 | PMC:PMC8429920 | DOI:10.1016/j.amsu.2021.102809 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: None Habibou Rabiou Idi Djibadje Haboubacar El Fakhr Kaoutar Liberat Musoni Hanane Ezzouine Boubaker Charra Source Type: research

Management of oro-antral fistula: Two case reports and review
We report in this article two-succefull cases of oro-antral fistula managed with buccal fat pad.PMID:34527240 | PMC:PMC8429925 | DOI:10.1016/j.amsu.2021.102817 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Samir Mainassara Chekaraou Laila Benjelloun Karima El Harti Source Type: research

Managing misdiagnosed gingival squamous cell carcinoma (GSCC) with occult symptoms: A report of two cases
CONCLUSION: Despite the rare incidence of Gingival squamous cell carcinoma (GSCC), clinicians should consider GSCC while investigating any localized lesion with nonspecific oral symptoms.PMID:34527241 | PMC:PMC8429914 | DOI:10.1016/j.amsu.2021.102820 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Fatima Alzhra Hanifa Aya Zazo Mohammad Kamel Fares Mohamad AlHashemi Bashar Bazkke Bakr Haddad Ammar Niazi Source Type: research

Factors associated with knowledge towards postoperative nausea and vomiting management among health professionals in referral Hospitals of Northwest Ethiopia. A multi-center cross-sectional study
Ann Med Surg (Lond). 2021 Sep 8;69:102825. doi: 10.1016/j.amsu.2021.102825. eCollection 2021 Sep.ABSTRACTBACKGROUND: Knowledge of health care professionals on postoperative nausea and vomiting (PONV) and antiemetic prescription trends affects patient's outcome after surgery and anesthesia and also patient and family satisfaction. Hence, knowing the knowledge status of health professionals towards PONV management is vital for the optimal care of surgical patients. Therefore, the study aimed to assess the knowledge and factors associated with PONV management among health professionals in referral hospitals of Northwest Ethio...
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Yewlsew Fentie Alle Hailu Yimer Tawuye Tadesse Belayneh Abraham Tarekegn Mersha Tikuneh Yetneberk Source Type: research

Totally endoscopic resection of epicardial cardiac haemangioma under on-pump beating heart
CONCLUSION: Totally endoscopic resection of CH under ON-BH is a safe, effective procedure, which can be adopted in similar cases.PMID:34527243 | PMC:PMC8433115 | DOI:10.1016/j.amsu.2021.102838 (Source: Annals of Medicine)
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Huu Cong Nguyen Dat Thanh Pham Source Type: research

Performance of fractional exhaled nitric oxide in predicting response to inhaled corticosteroids in chronic cough: a meta-analysis
Ann Med. 2021 Dec;53(1):1659-1672. doi: 10.1080/07853890.2021.1979242.ABSTRACTBackground. Chronic cough is a disabling condition with a high proportion of diagnostic and therapeutic failures. Fractional exhaled nitric oxide (FeNO) has been considered a useful biomarker for predicting inhaled corticosteroids (ICS) response. We evaluated the relationship between FeNO and ICS response in chronic cough by performing a systematic review with meta-analysis.Methods. PubMed, Web of Science, Scopus and EMBASE databases were systematically searched. Differences were expressed as Odds Ratio (OR) with 95% confidence intervals (95%CI)....
Source: Annals of Medicine - September 16, 2021 Category: Internal Medicine Authors: Pasquale Ambrosino Mariasofia Accardo Marco Mosella Antimo Papa Salvatore Fuschillo Giorgio Alfredo Spedicato Andrea Motta Mauro Maniscalco Source Type: research

Synthol systemic complications: Hypercalcemia and pulmonary granulomatosis. A case report
CONCLUSION: Synthol injection for body contouring may be a cause of extensive local and pulmonary foreign body granulomatosis leading to calcitriol mediated hypercalcemia. History of cosmetic injections should not be disregarded during history taking.PMID:34522373 | PMC:PMC8426527 | DOI:10.1016/j.amsu.2021.102771 (Source: Annals of Medicine)
Source: Annals of Medicine - September 15, 2021 Category: Internal Medicine Authors: Mersad Alimoradi Ahmad Chahal Elie El-Rassi Karim Daher Gazy Sakr Source Type: research