Targeting ferroptosis as a prospective therapeutic approach for diabetic nephropathy
Ann Med. 2024 Dec;56(1):2346543. doi: 10.1080/07853890.2024.2346543. Epub 2024 Apr 24.ABSTRACTDiabetic nephropathy (DN) is a severe complication of diabetes mellitus, causing a substantive threat to the public, which receives global concern. However, there are limited drugs targeting the treatment of DN. Owing to this, it is highly crucial to investigate the pathogenesis and potential therapeutic targets of DN. The process of ferroptosis is a type of regulated cell death (RCD) involving the presence of iron, distinct from autophagy, apoptosis, and pyroptosis. A primary mechanism of ferroptosis is associated with iron metab...
Source: Annals of Medicine - April 24, 2024 Category: Internal Medicine Authors: Qinrui Wu Fengjuan Huang Source Type: research
Perceived coaches' health promotion activity, maintenance of participation in sports, and lifestyle habits among emerging adults: a four-year follow-up study
CONCLUSIONS: Perceiving coaches' health promotion activity as frequent was related to maintained participation in organized sports among males. Maintainers were more likely to have more healthy lifestyle habits than nonparticipants and dropouts. There is a need to invest in coaches' health promotion activity when it is infrequent. A more detailed understanding is needed of coaches' health promotion activity that supports both maintained participation in sports, especially among females, and healthy lifestyle habits in emerging adulthood.PMID:38658832 | DOI:10.1080/07853890.2024.2321327 (Source: Annals of Medicine)
Source: Annals of Medicine - April 24, 2024 Category: Internal Medicine Authors: Katja Rinta-Antila Pasi Koski Tuula Aira Olli J Heinonen Raija Korpelainen Jari Parkkari Kai Savonen Kerttu Toivo Arja Uusitalo Maarit Valtonen Tommi Vasankari Jari Villberg Sami Kokko Source Type: research
Fecal microbiota is associated with extraintestinal manifestations in inflammatory bowel disease
CONCLUSIONS: The fecal microbiota in IBD patients with EIMs is distinct from that in IBD patients without EIM and could be important for EIM pathogenesis.PMID:38648495 | PMC:PMC11036898 | DOI:10.1080/07853890.2024.2338244 (Source: Annals of Medicine)
Source: Annals of Medicine - April 22, 2024 Category: Internal Medicine Authors: Sandra Hertz Jacqueline Moltzau Anderson Hans Linde Nielsen Claire Schachtschneider Kathryn E McCauley Mustafa Özçam Lone Larsen Susan V Lynch Henrik Nielsen Source Type: research
Fecal microbiota is associated with extraintestinal manifestations in inflammatory bowel disease
CONCLUSIONS: The fecal microbiota in IBD patients with EIMs is distinct from that in IBD patients without EIM and could be important for EIM pathogenesis.PMID:38648495 | DOI:10.1080/07853890.2024.2338244 (Source: Annals of Medicine)
Source: Annals of Medicine - April 22, 2024 Category: Internal Medicine Authors: Sandra Hertz Jacqueline Moltzau Anderson Hans Linde Nielsen Claire Schachtschneider Kathryn E McCauley Mustafa Özçam Lone Larsen Susan V Lynch Henrik Nielsen Source Type: research
Portable robots for upper-limb rehabilitation after stroke: a systematic review and meta-analysis
CONCLUSION: Although portable upper-limb rehabilitation robots are clinically beneficial, few studies have focused on portability. Further research should focus on modular design so that rehabilitation robots can be decomposed, which benefits remote rehabilitation and household applications.PMID:38640459 | PMC:PMC11034452 | DOI:10.1080/07853890.2024.2337735 (Source: Annals of Medicine)
Source: Annals of Medicine - April 19, 2024 Category: Internal Medicine Authors: Kevin C Tseng Le Wang Chunkai Hsieh Alice M Wong Source Type: research
Moral decision-making at night and the impact of night work with blue-enriched white light or warm white light: a counterbalanced crossover study
CONCLUSION: The results indicate that moral decisions during simulated night work in warm white light, but not blue-enriched white light, become less mature and principle-oriented, and more rule-based compared to daytime, hence blue-enriched white light may function as a moderator. Further studies are needed, and the findings should be tentatively considered.Trial registration: ClinicalTrials.gov (ID: NCT03203538) Registered: 26/06/2017; https://clinicaltrials.gov/study/NCT03203538.PMID:38635448 | PMC:PMC11028009 | DOI:10.1080/07853890.2024.2331054 (Source: Annals of Medicine)
Source: Annals of Medicine - April 18, 2024 Category: Internal Medicine Authors: Erlend Sunde Anette Harris Olav Kjellevold Olsen St åle Pallesen Source Type: research
Moral decision-making at night and the impact of night work with blue-enriched white light or warm white light: a counterbalanced crossover study
CONCLUSION: The results indicate that moral decisions during simulated night work in warm white light, but not blue-enriched white light, become less mature and principle-oriented, and more rule-based compared to daytime, hence blue-enriched white light may function as a moderator. Further studies are needed, and the findings should be tentatively considered.Trial registration: ClinicalTrials.gov (ID: NCT03203538) Registered: 26/06/2017; https://clinicaltrials.gov/study/NCT03203538.PMID:38635448 | DOI:10.1080/07853890.2024.2331054 (Source: Annals of Medicine)
Source: Annals of Medicine - April 18, 2024 Category: Internal Medicine Authors: Erlend Sunde Anette Harris Olav Kjellevold Olsen St åle Pallesen Source Type: research
A systematic review and network meta-analysis on the effectiveness of exercise-based interventions for reducing the injury incidence in youth team-sport players. Part 2: an analysis by movement patterns
The objectives of this network meta-analysis were: (a) to estimate and compare the pooled effects of some injury prevention programs (IPPs) whose exercise-based components were categorized using a movement pattern-specific taxonomy on reducing overall and some specific body regions (lower extremity, thigh, knee, and ankle) injury incidences in youth team sport athletes and (b) to explore the individual effects of these components on the injury incidence rates (IIRs) previously mentioned. Searches were performed in PubMed, Web of Science, SPORTDiscus, and Cochrane Library. Eligible criteria were: exercise-based intervention...
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Francisco Ayala Francisco Javier Robles-Palaz ón Desir ée Blázquez-Rincón Alejandro L ópez-Valenciano Jos é Antonio López-López Mark De Ste Croix Source Type: research
Cohabiting with ulcerative colitis patients decreases differences of gut microbiome between healthy individuals and the patients
Conclusion: Our study revealed that cohabitation with UC patients decreased differences in the gut microbiome between healthy individuals and patients. Not only was the composition and diversity of the microbiota diminished, but active pathways also showed some decline. Furthermore, Firmicutes, Faecalibacterium, and the four related pathways may be associated with the pathological state of the host rather than with human behavior.PMID:38614128 | PMC:PMC11017998 | DOI:10.1080/07853890.2024.2337712 (Source: Annals of Medicine)
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Chen Li Xiaoyan Guo Yan He Jing Wang Jianyu Hao Xinjuan Liu Source Type: research
A systematic review and network meta-analysis on the effectiveness of exercise-based interventions for reducing the injury incidence in youth team-sport players. Part 2: an analysis by movement patterns
The objectives of this network meta-analysis were: (a) to estimate and compare the pooled effects of some injury prevention programs (IPPs) whose exercise-based components were categorized using a movement pattern-specific taxonomy on reducing overall and some specific body regions (lower extremity, thigh, knee, and ankle) injury incidences in youth team sport athletes and (b) to explore the individual effects of these components on the injury incidence rates (IIRs) previously mentioned. Searches were performed in PubMed, Web of Science, SPORTDiscus, and Cochrane Library. Eligible criteria were: exercise-based intervention...
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Francisco Ayala Francisco Javier Robles-Palaz ón Desir ée Blázquez-Rincón Alejandro L ópez-Valenciano Jos é Antonio López-López Mark De Ste Croix Source Type: research
Cohabiting with ulcerative colitis patients decreases differences of gut microbiome between healthy individuals and the patients
Conclusion: Our study revealed that cohabitation with UC patients decreased differences in the gut microbiome between healthy individuals and patients. Not only was the composition and diversity of the microbiota diminished, but active pathways also showed some decline. Furthermore, Firmicutes, Faecalibacterium, and the four related pathways may be associated with the pathological state of the host rather than with human behavior.PMID:38614128 | PMC:PMC11017998 | DOI:10.1080/07853890.2024.2337712 (Source: Annals of Medicine)
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Chen Li Xiaoyan Guo Yan He Jing Wang Jianyu Hao Xinjuan Liu Source Type: research
A systematic review and network meta-analysis on the effectiveness of exercise-based interventions for reducing the injury incidence in youth team-sport players. Part 2: an analysis by movement patterns
The objectives of this network meta-analysis were: (a) to estimate and compare the pooled effects of some injury prevention programs (IPPs) whose exercise-based components were categorized using a movement pattern-specific taxonomy on reducing overall and some specific body regions (lower extremity, thigh, knee, and ankle) injury incidences in youth team sport athletes and (b) to explore the individual effects of these components on the injury incidence rates (IIRs) previously mentioned. Searches were performed in PubMed, Web of Science, SPORTDiscus, and Cochrane Library. Eligible criteria were: exercise-based intervention...
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Francisco Ayala Francisco Javier Robles-Palaz ón Desir ée Blázquez-Rincón Alejandro L ópez-Valenciano Jos é Antonio López-López Mark De Ste Croix Source Type: research
Cohabiting with ulcerative colitis patients decreases differences of gut microbiome between healthy individuals and the patients
Conclusion: Our study revealed that cohabitation with UC patients decreased differences in the gut microbiome between healthy individuals and patients. Not only was the composition and diversity of the microbiota diminished, but active pathways also showed some decline. Furthermore, Firmicutes, Faecalibacterium, and the four related pathways may be associated with the pathological state of the host rather than with human behavior.PMID:38614128 | PMC:PMC11017998 | DOI:10.1080/07853890.2024.2337712 (Source: Annals of Medicine)
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Chen Li Xiaoyan Guo Yan He Jing Wang Jianyu Hao Xinjuan Liu Source Type: research
A systematic review and network meta-analysis on the effectiveness of exercise-based interventions for reducing the injury incidence in youth team-sport players. Part 2: an analysis by movement patterns
The objectives of this network meta-analysis were: (a) to estimate and compare the pooled effects of some injury prevention programs (IPPs) whose exercise-based components were categorized using a movement pattern-specific taxonomy on reducing overall and some specific body regions (lower extremity, thigh, knee, and ankle) injury incidences in youth team sport athletes and (b) to explore the individual effects of these components on the injury incidence rates (IIRs) previously mentioned. Searches were performed in PubMed, Web of Science, SPORTDiscus, and Cochrane Library. Eligible criteria were: exercise-based intervention...
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Francisco Ayala Francisco Javier Robles-Palaz ón Desir ée Blázquez-Rincón Alejandro L ópez-Valenciano Jos é Antonio López-López Mark De Ste Croix Source Type: research
Cohabiting with ulcerative colitis patients decreases differences of gut microbiome between healthy individuals and the patients
Conclusion: Our study revealed that cohabitation with UC patients decreased differences in the gut microbiome between healthy individuals and patients. Not only was the composition and diversity of the microbiota diminished, but active pathways also showed some decline. Furthermore, Firmicutes, Faecalibacterium, and the four related pathways may be associated with the pathological state of the host rather than with human behavior.PMID:38614128 | DOI:10.1080/07853890.2024.2337712 (Source: Annals of Medicine)
Source: Annals of Medicine - April 13, 2024 Category: Internal Medicine Authors: Chen Li Xiaoyan Guo Yan He Jing Wang Jianyu Hao Xinjuan Liu Source Type: research
