Lrp13a and Lrp13b serve as vitellogenin receptors in the ovary of zebrafish †
Biol Reprod. 2024 Apr 24:ioae040. doi: 10.1093/biolre/ioae040. Online ahead of print.ABSTRACTIn oviparous animals, egg yolk is largely derived from vitellogenin, which is taken up from the maternal circulation by the growing oocytes via the vitellogenin receptor. Recently, a novel member of the lipoprotein receptor superfamily termed low-density lipoprotein receptor-related protein 13 was identified and proposed as a candidate of vitellogenin receptor in oviparous animals. However, the roles of low-density lipoprotein receptor-related protein 13 in vitellogenesis are still poorly defined. Here, we investigated the expressi...
Source: Reproductive Biology - April 25, 2024 Category: Reproduction Medicine Authors: Zhiquan Liu Nan Zhang Chuangxin Wang Lina Shi Yixuan Hu Yamei Wang Jianzhen Li Source Type: research

Factors defining developmental competence of bovine oocytes collected for in vitro embryo production
Biol Reprod. 2024 Apr 25:ioae065. doi: 10.1093/biolre/ioae065. Online ahead of print.ABSTRACTDespite the currently relatively low effectiveness of producing bovine embryos in vitro, there is a growing interest in applying this laboratory method in the field of reproduction. Many aspects of the procedure need to be improved. One of the main problems is the inferior developmental competence of in vitro matured oocytes that are collected using the ovum pick-up (OPU) method. The mechanisms of oocyte capacitation and maturation, as well as the in vivo conditions in which they grow and mature, should be carefully analyzed. A del...
Source: Reproductive Biology - April 25, 2024 Category: Reproduction Medicine Authors: Aleksandra Teresa Pytel Krystyna Żyżyńska-Galeńska Zdzis ław Gajewski Krzysztof Papis Source Type: research

Evaluation of serum CA125, HE4 and CA724 and the risk of ovarian malignancy algorithm score in the diagnosis of high-grade serous ovarian cancer
CONCLUSION: The new algorithm using CA125 and BRCA1/2 helped to distinguish between patients with HGSOC and patients with non-HGSOC.PMID:38663180 | DOI:10.1016/j.ejogrb.2024.04.022 (Source: Reproductive Biology)
Source: Reproductive Biology - April 25, 2024 Category: Reproduction Medicine Authors: Deyu Hu Jun Qian Fenghua Yin Bing Wei Jiayu Wang Huijuan Zhang Haiou Yang Source Type: research

Immunomodulation of Ethyl pyruvate on gestational diabetes mellitus in Mice; The impact on Th17/Treg balance
In conclusion, EP could modulate GDM in mice and might be a potential therapeutic strategy candidate for the treatment of patients with GDM.PMID:38663253 | DOI:10.1016/j.repbio.2024.100861 (Source: Reproductive Biology)
Source: Reproductive Biology - April 25, 2024 Category: Reproduction Medicine Authors: Min Zhao Xiuping Bian Li Meng Source Type: research

Perinatal Science International: A new meeting of the European Association of Perinatal Medicine
Eur J Obstet Gynecol Reprod Biol. 2024 Apr 15;297:159-160. doi: 10.1016/j.ejogrb.2024.04.018. Online ahead of print.NO ABSTRACTPMID:38657520 | DOI:10.1016/j.ejogrb.2024.04.018 (Source: Reproductive Biology)
Source: Reproductive Biology - April 24, 2024 Category: Reproduction Medicine Authors: Neena Modi Bo Jacobsson Diogo Ayres de Campos Perinatal Science International Writing Group Source Type: research

Changes in metabolic acidosis following birth in intensive care unit neonates
CONCLUSIONS: Changes in pH and base excess occurred over a wide range between delivery and the first newborn blood gas in the first 6 h of life, and we identified several factors associated with direction of change. Metabolic acidosis at birth cannot reliably be inferred from neonatal arterial values. Neonatal acidosis, including acidosis following a normal pH and base excess at birth, was associated with morbidity and mortality.PMID:38657521 | DOI:10.1016/j.ejogrb.2024.04.025 (Source: Reproductive Biology)
Source: Reproductive Biology - April 24, 2024 Category: Reproduction Medicine Authors: Natalie T Simon Patricia M Hagan Karilynn M Rockhill Kent D Heyborne Source Type: research

Fresh or frozen day 6 blastocyst transfer: is there still a question?
CONCLUSIONS: Our results indicate that transferring D6 blastocysts in frozen cycles improves the LBR, making it the best embryo transfer strategy for these slow-growing embryos.CLINICAL TRIAL NUMBER: Not applicable.PMID:38659014 | DOI:10.1186/s12958-024-01214-w (Source: Reproductive Biology)
Source: Reproductive Biology - April 24, 2024 Category: Reproduction Medicine Authors: Lucile Ferreux Mathilde Bourdon Ahmed Chargui Julie Firmin Chlo é Maignien Pietro Santulli Catherine Patrat Khaled Pocate-Cheriet Source Type: research

Comparing the efficacy and pregnancy outcome of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis in infertile women: a prospective, randomized, controlled trial study
CONCLUSION: Inserting a balloon or placing an IUD for one or two months can effectively lower the risk of adhesion recurrence and restore the shape of the uterine cavity. While the therapeutic effect of the balloon was superior to that of the IUD, no significant differences were observed in the one-month and two-month IUD groups.TRIAL REGISTRATION: This research was registered in the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/enIndex.aspx ); Clinical trial registry identification number: ChiCTR-IOR-17,011,943 ( http://www.chictr.org.cn/showprojen.aspx?proj=17979 ). Date of trial registration: July 11, 2017....
Source: Reproductive Biology - April 23, 2024 Category: Reproduction Medicine Authors: HaiXia Ding Honghong Zhang Rui Qiao Ningxia Sun Yixuan Ji Wenjuan Pang Wen Li Qing Zhang Source Type: research

Comparing the efficacy and pregnancy outcome of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis in infertile women: a prospective, randomized, controlled trial study
CONCLUSION: Inserting a balloon or placing an IUD for one or two months can effectively lower the risk of adhesion recurrence and restore the shape of the uterine cavity. While the therapeutic effect of the balloon was superior to that of the IUD, no significant differences were observed in the one-month and two-month IUD groups.TRIAL REGISTRATION: This research was registered in the Chinese Clinical Trial Registry ( http://www.chictr.org.cn/enIndex.aspx ); Clinical trial registry identification number: ChiCTR-IOR-17,011,943 ( http://www.chictr.org.cn/showprojen.aspx?proj=17979 ). Date of trial registration: July 11, 2017....
Source: Reproductive Biology - April 23, 2024 Category: Reproduction Medicine Authors: HaiXia Ding Honghong Zhang Rui Qiao Ningxia Sun Yixuan Ji Wenjuan Pang Wen Li Qing Zhang Source Type: research

Molecular mechanism of autophagy and apoptosis in endometriosis: Current understanding and future research directions
CONCLUSION: Endometriotic cells may have acquired antiapoptotic mechanisms through unique intrinsic and extrinsic autophagy pathways to survive in changing environments.PMID:38645639 | PMC:PMC11031673 | DOI:10.1002/rmb2.12577 (Source: Reproductive Biology)
Source: Reproductive Biology - April 22, 2024 Category: Reproduction Medicine Authors: Hiroshi Kobayashi Shogo Imanaka Chiharu Yoshimoto Sho Matsubara Hiroshi Shigetomi Source Type: research

Viewing early life without labels: optical approaches for imaging the early embryo
Biol Reprod. 2024 Apr 22:ioae062. doi: 10.1093/biolre/ioae062. Online ahead of print.ABSTRACTEmbryo quality is an important determinant of successful implantation and a resultant live birth. Current clinical approaches for evaluating embryo quality rely on subjective morphology assessments or an invasive biopsy for genetic testing. However, both approaches can be inherently inaccurate and crucially, fail to improve the live birth rate following the transfer of in vitro produced embryos. Optical imaging offers a potential non-invasive and accurate avenue for assessing embryo viability. Recent advances in various label-free ...
Source: Reproductive Biology - April 22, 2024 Category: Reproduction Medicine Authors: Darren J X Chow Tiffany C Y Tan Avinash Upadhya Megan Lim Kishan Dholakia Kylie R Dunning Source Type: research

HMGB1 regulates autophagy of placental trophoblast through ERK signaling pathway
CONCLUSIONS: HMGB1 participates in the regulation of autophagy through the ERK signaling pathway and affects placental development.PMID:38647664 | DOI:10.1093/biolre/ioae064 (Source: Reproductive Biology)
Source: Reproductive Biology - April 22, 2024 Category: Reproduction Medicine Authors: Ming-Rui Li En-Xiang Chen Zhuo-Hang Li Hong-Lan Song Yi Zhang Fang-Fang Li You-Long Xie Jing Tang Yu-Bin Ding Li-Juan Fu Source Type: research

Pregnancy and acromegaly: clinical outcomes of retrospectively analysed data from the German acromegaly registry
CONCLUSION: Pregnancies in women with acromegaly are possible and the course of pregnancy is in general safe for mother and child both with and without specific treatment for acromegaly. The prevalence of concomitant metabolic diseases such as gestational diabetes is comparable to the prevalence in healthy pregnant women. Nevertheless, larger studies with more data in pregnant patients with acromegaly are needed to provide safe and effective care for pregnant women with this condition.PMID:38650041 | PMC:PMC11034139 | DOI:10.1186/s12958-024-01207-9 (Source: Reproductive Biology)
Source: Reproductive Biology - April 22, 2024 Category: Reproduction Medicine Authors: Anke T önjes Marleen W ürfel Marcus Quinkler Ulrich J Knappe J ürgen Honegger Nina Krause-Joppig Konrad Bacher Timo Deutschbein Sylv ère Störmann Jochen Schopohl Sebastian M Meyh öfer participants of the German Acromegaly Registry Source Type: research

Effects of MEK1/2 inhibitor U0126 on FGF10-enhanced buffalo oocyte maturation in vitro
Reprod Biol. 2024 Apr 20;24(2):100883. doi: 10.1016/j.repbio.2024.100883. Online ahead of print.ABSTRACTFibroblast growth factor 10 (FGF10) plays critical roles in oocyte maturation and embryonic development; however, the specific pathway by which FGF10 promotes in vitro maturation of buffalo oocytes remains elusive. The present study was aimed at investigating the mechanism underlying effects of the FGF10-mediated extracellular regulated protein kinases (ERK) pathway on oocyte maturation and embryonic development in vitro. MEK1/2 (mitogen-activated protein kinase kinase) inhibitor U0126, alone or in combination with FGF10...
Source: Reproductive Biology - April 21, 2024 Category: Reproduction Medicine Authors: Shanshan Du Yanxin Wang Fenghua Lu Wenting Zhou Source Type: research

Vaginal foreign body in the pediatric patient: A systematic review
CONCLUSION: A swift and accurate diagnosis is crucial, with clinical examination and ultrasonography playing pivotal roles. Vaginoscopy is the gold standard for definitive diagnosis and therapy. Attention should be given to a potential context of sexual abuse.PMID:38643730 | DOI:10.1016/j.ejogrb.2024.04.019 (Source: Reproductive Biology)
Source: Reproductive Biology - April 21, 2024 Category: Reproduction Medicine Authors: E Umans M Boogaerts B Vergauwe A Verest S Van Calenbergh Source Type: research