Age-related increase in live-birth rates of first frozen thaw embryo versus first fresh transfer in initial assisted reproductive technology cycles without PGT
CONCLUSIONS: Overall LBR and CLBR were greater for first FET than fresh transfers with incremental increases in odds of live birth with advancing age, suggesting the presence of a more favorable age-related change in endometrial receptivity present in frozen-thawed cycles. For both DOR and MF cycles, LBR and CLBR after primary transfer were greater for first FET than fresh. However, this was particularly evident in older ages for DOR cycles. This suggests that supraphysiologic stimulation in older DOR cycles may be detrimental to endometrial receptivity, which is in part corrected for in FET cycles.PMID:38615016 | PMC:PMC1...
Source: Reproductive Biology - April 13, 2024 Category: Reproduction Medicine Authors: Sarah F Wang David B Seifer Source Type: research
Corrigendum to 'Transcriptomic profile of GLCs of PCOS women highlights metabolic dysregulation as a plausible contributor to PCOS pathophysiology' Reproductive Biology, Volume 23, Issue 3 (2023), 100787
Reprod Biol. 2024 Apr 13:100885. doi: 10.1016/j.repbio.2024.100885. Online ahead of print.NO ABSTRACTPMID:38614814 | DOI:10.1016/j.repbio.2024.100885 (Source: Reproductive Biology)
Source: Reproductive Biology - April 13, 2024 Category: Reproduction Medicine Authors: Krutika Patil Aalaap Naigaonkar Indira Hinduja Srabani Mukherjee Source Type: research
Age-related increase in live-birth rates of first frozen thaw embryo versus first fresh transfer in initial assisted reproductive technology cycles without PGT
CONCLUSIONS: Overall LBR and CLBR were greater for first FET than fresh transfers with incremental increases in odds of live birth with advancing age, suggesting the presence of a more favorable age-related change in endometrial receptivity present in frozen-thawed cycles. For both DOR and MF cycles, LBR and CLBR after primary transfer were greater for first FET than fresh. However, this was particularly evident in older ages for DOR cycles. This suggests that supraphysiologic stimulation in older DOR cycles may be detrimental to endometrial receptivity, which is in part corrected for in FET cycles.PMID:38615016 | DOI:10.1...
Source: Reproductive Biology - April 13, 2024 Category: Reproduction Medicine Authors: Sarah F Wang David B Seifer Source Type: research
Extended-release versus oral buprenorphine as opioid maintenance treatment during pregnancy-maternal and neonatal outcomes
CONCLUSIONS: Extended-release buprenorphine with steady drug concentration seems to be a promising pharmacotherapy option during pregnancy for mothers. Maternal health during pregnancy may contribute to the well-being of newborns. Larger trials are urgently needed to confirm these results..PMID:38608352 | DOI:10.1016/j.ejogrb.2024.04.003 (Source: Reproductive Biology)
Source: Reproductive Biology - April 12, 2024 Category: Reproduction Medicine Authors: Minna Kanervo Sarimari Tupola Eeva Nikkola Krista Rantakari Hanna Kahila Source Type: research
The Experience of Anaemia and Ingesting Oral Iron Supplementation in Pregnancy: A Qualitative Study
CONCLUSION: In order to successfully reduce the rates of iron deficiency anaemia in pregnancy, it is crucial that all factors affecting compliance with oral iron are considered. Providing women with the important information on the possible consequences of sub optimally treated anaemia may help to improve this public health issue.PMID:38608353 | DOI:10.1016/j.ejogrb.2024.03.005 (Source: Reproductive Biology)
Source: Reproductive Biology - April 12, 2024 Category: Reproduction Medicine Authors: F E O'Toole E Hokey F M McAuliffe J M Walsh Source Type: research
A randomized, prospective, controlled study comparing uterine preserving laparoscopic lateral suspension with mesh versus laparoscopic sacrohysteropexy in the treatment of uterine prolapse
CONCLUSION: Both methods effectively managed apical prolapse with similar outcomes. Objective measurements showed lateral suspension's superiority in reducing bladder descent.PMID:38608354 | DOI:10.1016/j.ejogrb.2024.03.042 (Source: Reproductive Biology)
Source: Reproductive Biology - April 12, 2024 Category: Reproduction Medicine Authors: Ozan Do ğan Murat Yassa Ecem Eren P ınar Birol İlter Niyazi Tu ğ Source Type: research
Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease †
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive tract as well as its successful application of shear wave elastography to reproductive tissues, including the uterus and cervix. We also describe an emerging use of this technology in evaluation of human ovarian stiffness via transvaginal ultrasound. Establishing ovarian stiffness as a clinical biomarker of ovarian aging may have implications for predicting the ovarian reserve and outcomes of Assisted Reproductive Technologies as well as for the assessment of the efficacy of emerging therapeu...
Source: Reproductive Biology - April 12, 2024 Category: Reproduction Medicine Authors: Emily J Zaniker Man Zhang Lydia Hughes Lizellen La Follette Tomiris Atazhanova Alexis Trofimchuk Elnur Babayev Francesca E Duncan Source Type: research
Prenatal chromosomal microarray analysis and karyotyping in fetuses with isolated choroid plexus cyst: A retrospective case-control study
CONCLUSIONS: The presence of iCPC on ultrasound examination suggests a potential indication for genetic counseling. Karyotyping and chromosomal microarray analysis may be considered for fetuses with iCPC. It is important to be aware of the limitations of non-invasive prenatal testing, as there is a possibility of residual risk.PMID:38603985 | DOI:10.1016/j.ejogrb.2024.04.002 (Source: Reproductive Biology)
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Linlin Wang Ping Liang Pingshan Pan Jiasun Su Jiayi Qin Zhaoxia Chen Dongbing Huang Weijia Sun Pengshu Song Hongwei Wei Source Type: research
N-terminal prohormone of brain natriuretic peptide in gestational hypertension and preeclampsia - State of the art
Eur J Obstet Gynecol Reprod Biol. 2024 Apr 9;297:96-105. doi: 10.1016/j.ejogrb.2024.04.007. Online ahead of print.ABSTRACTN-terminal prohormone of brain natriuretic peptide (NT-proBNP) is a non-active prohormone secreted by ventricular cardiomyocytes into the circulation in response to ventricle overload, mainly due to increased blood volume. The changes in NT-proBNP levels during pregnancy have been investigated in multiple studies. In the case of hypertensive disorders of pregnancy, increased vasoconstriction leads to increased blood pressure and afterload. Together with the volume overload of pregnancy, it leads to high...
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Natalia Ros ół Grzegorz Procyk Joanna Kacperczyk-Bartnik Marcin Grabowski Aleksandra G ąsecka Source Type: research
Intrauterine infusion of platelet-rich plasma improves fibrosis by transforming growth factor beta 1/Smad pathway in a rat intrauterine adhesion model
This study aims to elucidate the effects of Platelet-rich plasma (PRP) in fibrosis development in intrauterine adhesion (IUA), and the associated underlying mechanisms are also explored, which are expected to be a potential therapeutic scheme for IUA. In this research, PRP was obtained and prepared from the peripheral venous blood of rats. A rat model was induced by mechanical injury. Further, PRP was directly injected into the uterus for treatment. The appearance and shape of the uterus were assessed based on the tissues harvested. The fibrosis biomarker levels were analyzed. The transforming growth factor beta 1 (TGF-β1...
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Hongwen Yang Wenmin Zhang Jingchuan Fang Zhihan Tang Yanni Zhou Hongzhen Hu Miao Miao Yu Yao Source Type: research
Immunotherapy combined with targeted therapy in advanced small cell carcinoma of the ovary of hypercalcemic type: A case of overall survival lasting for over 5 years
Eur J Obstet Gynecol Reprod Biol. 2024 Apr 6:S0301-2115(24)00168-4. doi: 10.1016/j.ejogrb.2024.04.001. Online ahead of print.ABSTRACTSmall cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but highly aggressive ovarian malignant neoplasm lacking a unified clinical management process. Most patients are diagnosed at an advanced stage and have an extremely poor prognosis with an overall probability of survival less than 10 %. Here, we describe the case of a patient with advanced SCCOHT achieved a survival of over 5 years after receiving multiple cycles of immunotherapy combined with anti-angiogenic therapy or...
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Yi Gao Li Zang Yingfei Ye Fenghua Ma Mingyi Kang Kewei Zheng Yu Kang Haitao Wang Congjian Xu Source Type: research
Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression
CONCLUSION: Our study demonstrated that cisplatin could induce ferroptosis in granulosa cells, while EnSCs could inhibit ferroptosis and thus exert repair effects on the cisplatin-induced injury model both in vivo and in vitro. Meanwhile, Nrf2 was validated to participate in this regulatory process and played an essential role.PMID:38605340 | PMC:PMC11008046 | DOI:10.1186/s12958-024-01208-8 (Source: Reproductive Biology)
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Rumeng Pan Rongli Wang Feiyan Cheng Lihui Wang Zhiwei Cui Jing She Xinyuan Yang Source Type: research
Prenatal chromosomal microarray analysis and karyotyping in fetuses with isolated choroid plexus cyst: A retrospective case-control study
CONCLUSIONS: The presence of iCPC on ultrasound examination suggests a potential indication for genetic counseling. Karyotyping and chromosomal microarray analysis may be considered for fetuses with iCPC. It is important to be aware of the limitations of non-invasive prenatal testing, as there is a possibility of residual risk.PMID:38603985 | DOI:10.1016/j.ejogrb.2024.04.002 (Source: Reproductive Biology)
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Linlin Wang Ping Liang Pingshan Pan Jiasun Su Jiayi Qin Zhaoxia Chen Dongbing Huang Weijia Sun Pengshu Song Hongwei Wei Source Type: research
N-terminal prohormone of brain natriuretic peptide in gestational hypertension and preeclampsia - State of the art
Eur J Obstet Gynecol Reprod Biol. 2024 Apr 9;297:96-105. doi: 10.1016/j.ejogrb.2024.04.007. Online ahead of print.ABSTRACTN-terminal prohormone of brain natriuretic peptide (NT-proBNP) is a non-active prohormone secreted by ventricular cardiomyocytes into the circulation in response to ventricle overload, mainly due to increased blood volume. The changes in NT-proBNP levels during pregnancy have been investigated in multiple studies. In the case of hypertensive disorders of pregnancy, increased vasoconstriction leads to increased blood pressure and afterload. Together with the volume overload of pregnancy, it leads to high...
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Natalia Ros ół Grzegorz Procyk Joanna Kacperczyk-Bartnik Marcin Grabowski Aleksandra G ąsecka Source Type: research
Intrauterine infusion of platelet-rich plasma improves fibrosis by transforming growth factor beta 1/Smad pathway in a rat intrauterine adhesion model
This study aims to elucidate the effects of Platelet-rich plasma (PRP) in fibrosis development in intrauterine adhesion (IUA), and the associated underlying mechanisms are also explored, which are expected to be a potential therapeutic scheme for IUA. In this research, PRP was obtained and prepared from the peripheral venous blood of rats. A rat model was induced by mechanical injury. Further, PRP was directly injected into the uterus for treatment. The appearance and shape of the uterus were assessed based on the tissues harvested. The fibrosis biomarker levels were analyzed. The transforming growth factor beta 1 (TGF-β1...
Source: Reproductive Biology - April 11, 2024 Category: Reproduction Medicine Authors: Hongwen Yang Wenmin Zhang Jingchuan Fang Zhihan Tang Yanni Zhou Hongzhen Hu Miao Miao Yu Yao Source Type: research
