Tuning Structural Characteristics of Corn Stover Through Ammonium and Sodium Sulfite (ASS) Pretreatment for Enhanced Enzymatic Hydrolysis
In this study, we have updated the AFEX pretreatment method; ammonia and sodium sulfite (ASS) can be used to produce a more digestible substrate. The results demonstrate that ASS-pretreated corn stover (CS) yields a higher fermentable sugar yield compared with AFEX pretreatment, even at lower enzyme loadings. Specifically, at an enzyme loading of 12 mg protein/g glucan, ASS-CS achieved 88.8% glucose and 80.6% xylose yield. Characterization analysis reveals that lignin underwent sulfonation during ASS pretreatment. This modification results in a more negative zeta potential for ASS-CS, indicating a reduction in nonproductiv...
Source: Applied Biochemistry and Biotechnology - April 26, 2024 Category: Biochemistry Authors: Xiangxue Chen Shizhong Yang Shuiping Ouyang Xinchuan Yuan Junlin Song Shuai Ding Yuanyuan Sha Rui Zhai Source Type: research
Tropomyosin 2 Regulates Tumor Cell Proliferation, Immune Suppression, and Activation of the JNK Signaling Pathway in Colitis-Associated Cancer (CAC)
CONCLUSIONS: Our results demonstrated that TPM2 knockdown suppressed the proliferation of CAC IECs, enhanced immune suppression on CAC IECs, and inhibited the JNK signaling pathway within the framework of CAC. These findings suggest TPM2 can serve as a potential therapeutic target for CAC treatment.PMID:38665026 | DOI:10.24976/Discov.Med.202436183.73 (Source: Cancer Control)
Source: Cancer Control - April 26, 2024 Category: Cancer & Oncology Authors: Aixi Sun Jian Ge Kaixin Ding Zhiyang Gao Yun Zhang Source Type: research
CLSI-based verification and < em > de novo < /em > establishment of reference intervals for common biochemical assays in Croatian newborns
CONCLUSIONS: The CALIPER reference intervals can be implemented into routine laboratory and clinical practice for the tested newborn population for most of the analyzed assays, while own reference intervals for potassium, magnesium and direct bilirubin have been determined.PMID:38665867 | PMC:PMC11042559 | DOI:10.11613/BM.2024.020705 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Iva Fri ščić Sonja Perkov Andrea Radeljak Jasminka Stipanovi ć-Kastelić Mirjana Mariana Kardum Paro Source Type: research
Total synthesis of jamaicamide B
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Ryosuke Shigeta, Takahiro Suzuki, Kazuki Kaneko, Hiroaki Tanaka, Ibuki Haishima, Kanata Norio, Ayano Tanaka-Yanuma, Toyonobu Usuki Jamaicamide B was isolated from the cyanobacterium Moorea producens in Jamaica and shows neurotoxicity as a sodium channel blocker. This unique mixed peptide-polyketide structure contains a pyrrolinone ring, a β-methoxy... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - April 26, 2024 Category: Molecular Biology Authors: Ryosuke Shigeta Source Type: research
A cohort study of sodium-glucose cotransporter-2 inhibitors after acute kidney injury among Veterans with diabetic kidney disease.
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce the risk for several adverse outcomes among patients with diabetic kidney disease. Yet, optimal timing for SGLT2i after acute kidney injury (AKI) is uncertain, as are the providers responsible for post-AKI SGLT2i initiation. Using a retrospective cohort of United States Veterans with diabetes mellitus type 2 and proteinuria, we examined encounters by provider specialty before SGLT2i initiation and subsequent all-cause mortality after hospitalization with AKI, defined by a 50% or more rise in serum creatinine. (Source: Kidney International)
Source: Kidney International - April 26, 2024 Category: Urology & Nephrology Authors: Daniel P. Murphy, Julian Wolfson, Scott Reule, Kirsten L. Johansen, Areef Ishani, Paul E. Drawz Tags: clinical investigation Source Type: research
Human and camel cystic echinococcosis – a polyclonal antibody-based sandwich ELISA for its serodiagnosis with molecular identification
In conclusion, Sandwich ELISA technique was found to be a potent and sensitive assay for detection of hydatid antigen in both human and camel samples. (Source: Veterinary Research Communications)
Source: Veterinary Research Communications - April 26, 2024 Category: Veterinary Research Source Type: research
Decellularized kidney capsule as a three-dimensional scaffold for tissue regeneration
AbstractTissue regeneration is thought to have considerable promise with the use of scaffolds designed for tissue engineering. Although polymer-based scaffolds for tissue engineering have been used extensively and developed quickly, their ability to mimic the in-vivo milieu, overcome immunogenicity, and have comparable mechanical or biochemical properties has limited their capability for repair. Fortunately, there is a compelling method to get around these challenges thanks to the development of extracellular matrix (ECM) scaffolds made from decellularized tissues. We used ECM decellularized sheep kidney capsule tissue in ...
Source: Cell and Tissue Banking - April 26, 2024 Category: Stem Cells Source Type: research
A systematic review and meta-analysis of diagnostic performance of fluorescein-guided sentinel lymph node biopsy in early breast cancer
ConclusionFluorescein-guided SLNB is a viable option for detection of lymph node metastases in clinically node negative patients with early breast cancer. It achieves a high pooled Sentinel Lymph Node Identification Rate (SLN-IR) of 93% with a false negative rate of 5.6% for the detection of axillary lymph node metastasis. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - April 26, 2024 Category: Cancer & Oncology Source Type: research
Evaluation of Rhododendri Mollis Flos and its representative component as a potential analgesic
In conclusion, the chemical substances and biological effects ofR. mole Flos changed significantly before and after processing, and the representative component RJ-VI has the potential to be developed into an effective analgesic.Graphical abstract (Source: Journal of Natural Medicines)
Source: Journal of Natural Medicines - April 26, 2024 Category: Drugs & Pharmacology Source Type: research
Genes, Vol. 15, Pages 555: GhCLCc-1, a Chloride Channel Gene from Upland Cotton, Positively Regulates Salt Tolerance by Modulating the Accumulation of Chloride Ions
gbin Ma
Wei Liu
The ionic toxicity induced by salinization has adverse effects on the growth and development of crops. However, researches on ionic toxicity and salt tolerance in plants have focused primarily on cations such as sodium ions (Na+), with very limited studies on chloride ions (Cl&minus;). Here, we cloned the homologous genes of Arabidopsis thaliana&nbsp;AtCLCc, GhCLCc-1A/D, from upland cotton (Gossypium hirsutum), which were significantly induced by NaCl or KCl treatments. Subcellular localization showed that GhCLCc-1A/D were both localized to the tonoplast. Complementation of Arabidopsis...
Source: Genes - April 26, 2024 Category: Genetics & Stem Cells Authors: Wenhao Li Siqi Gao Yinghao Zhao Yuchen Wu Xiaona Li Jianing Li Wei Zhu Zongbin Ma Wei Liu Tags: Article Source Type: research
The Effect of Sodium-Glucose Transporter 2 Inhibitors on Stroke in Patients With Type 2 Diabetes: A Meta-analysis
To provide an update on the effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on stroke in patients with type 2 diabetes (T2D). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2024 Category: Neurology Authors: Eric Pasqualotto, Farley Reis Rodrigues, Giovana Barros e Silva Ribeiro, Gustavo de Oliveira Almeida, J úlia Camargo Kabariti, Rafael Oliva Morgado Ferreira, Matheus Pedrotti Chavez, Mariana R.C. Clemente, Nicole B. Sur, Daniel G. Di Luca Source Type: research
Comparison of central diabetes insipidus (antidiuretic hormone deficiency) and stalk effect in patients with adamantinomatous and papillary craniopharyngioma
AbstractCraniopharyngioma (CP), a rare benign intracranial tumor, is still a major clinical challenge. There are two major histologic phenotypes: papillary CP (PCP) and adamantinomatous CP (ACP). This research aimed to assess the occurrence of central diabetes insipidus (antidiuretic hormone deficiency), the level of prolactin, and the stalk effect between PCP and ACP subtypes prior to and after surgery. Clinical data of CP patients before and after surgical resection of the tumor were analyzed retrospectively. These patients were divided into PCP and ACP groups, in accordance with the pathologic classification. The data o...
Source: Acta Neurologica Belgica - April 26, 2024 Category: Neurology Source Type: research
Achieving Long-Lived White Circularly Polarized Luminescence from Carbonized Polymer Dots via Phosphorescence Resonance Energy Transfer
Chem. Commun., 2024, Accepted Manuscript DOI: 10.1039/D4CC00532E, CommunicationFeixiang Wang, Yijie Wang, Rui Guo, Yushuang Wu, Shengju Zhou, Haibin Xiao, Xiaofeng Sun Achieving white-light emission, especially long-lived white circularly polarized luminescence is challenging. Herein, chiral phosphorescent carbonized polymer dots (CPDs) have been prepared by using chiral polymer sodium alginate and chiral small... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
Source: RSC - Chem. Commun. latest articles - April 25, 2024 Category: Chemistry Authors: Feixiang Wang Source Type: research
Knockdown of TOP2A suppresses IL ‐17 signaling pathway and alleviates the progression of ulcerative colitis
ConclusionKnockdown of TOP2A alleviated the progression of UC by suppressing inflammation and inhibited IL-17 signaling pathway. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 25, 2024 Category: Allergy & Immunology Authors: Ou Li,
Xuexiao Li,
Jianping He Tags: ORIGINAL ARTICLE Source Type: research
Continuous Flow Electrochemical Synthesis of Olivine ‐Structured NaFePO4 Cathode Material for Sodium‐Ion Batteries from Recycle LiFePO4
Schematic of the working principle of a continuous flow electrochemical solid-liquid coupled reactor for the synthesis of NFP, by which NFP is successfully synthesized at 50% of the theoretical reductant dosage. The binding energy of NaxFePO4 (0< x< 0.95) is calculated to investigate the incomplete insertion of sodium ions during NFP synthesis. AbstractTo mitigate the environmental impact of the improper disposal of spent LiFePO4 batteries and reduce resource waste, the development of LiFePO4 recycling technologies is of paramount importance. Meanwhile, olivine-structured NaFePO4 in sodium-ion batteries has received ...
Source: Small - April 25, 2024 Category: Nanotechnology Authors: Tongtong Gan,
Jiashu Yuan,
Fang Chen,
Guodong Zhang,
Laihao Liu,
Li Zhou,
Yunfang Gao,
Yonggao Xia Tags: Research Article Source Type: research
