Posterior reversible encephalopathy syndrome: characteristics, diagnostic accuracy, prognostic factors and long-term outcome in a paediatric population
AbstractPosterior reversible leukoencephalopathy syndrome (PRES) is a rare entity among children, characterised by acute neurological symptoms and radiological findings. The role of clinical symptoms and neuroimaging in predicting the prognosis of PRES have not been well-characterised. A retrospective descriptive study of children with PRES, admitted to a Paediatric Intensive Care Unit during a 10-year period, was performed to describe its characteristics, compare the accuracy of computed tomography (CT) scan and MRI on diagnosis and identify prognostic factors on paediatric population. Sixteen cases were identified. Most ...
Source: Acta Neurologica Belgica - October 24, 2021 Category: Neurology Source Type: research

D-dimer elevation after first alemtuzumab administration in a multiple sclerosis patient: case report
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 24, 2021 Category: Neurology Source Type: research

Sporadic Creutzfeldt –Jakob disease as a mimic of progressive supranuclear palsy
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 24, 2021 Category: Neurology Source Type: research

Physical activity level is associated with gait performance and five times sit-to-stand in Parkinson ’s disease individuals
AbstractBackgroundPhysical activity (PA) level is decreased in individuals with Parkinson ´s disease (PD). To increase the PA level improves both motor and non-motor symptoms of this population. It is known that gait performance and five times sit-to-stand (FTSTS) are associated with PA level; therefore, it is of great relevance for rehabilitation purposes to understand whether these va riables may predict PA level of individuals with PD.ObjectiveTo investigate whether gait performance and FTSTS are predictors of PA level.MethodsCross-sectional study with individuals with idiopathic PD modified Hoehn and Yahr staging...
Source: Acta Neurologica Belgica - October 23, 2021 Category: Neurology Source Type: research

Endovascular treatment of posterior inferior cerebellar artery trunk aneurysm
ConclusionFor PICA trunk aneurysms, the treatment choice should be assessed on a case-by-case basis. The rate of permanent morbidity of the EVT is low. EVT is an effective method for treating PICA trunk aneurysms. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 22, 2021 Category: Neurology Source Type: research

Association of ATG5 gene polymorphism with Parkinson ’s disease in a Han Chinese population
ConclusionThese findings suggest that genetic variations in the ATG5 gene and low levels of the ATG5 protein are associated with susceptibility to PD and with cognitive impairment in PD patients. ATG5 could be a potential biomarker to assess the severity and prognosis of PD. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 18, 2021 Category: Neurology Source Type: research

Postpartum ischemic stroke: a successful intravenous thrombolysis
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 18, 2021 Category: Neurology Source Type: research

Association of ATG5 gene polymorphism with Parkinson ’s disease in a Han Chinese population
ConclusionThese findings suggest that genetic variations in the ATG5 gene and low levels of the ATG5 protein are associated with susceptibility to PD and with cognitive impairment in PD patients. ATG5 could be a potential biomarker to assess the severity and prognosis of PD. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 18, 2021 Category: Neurology Source Type: research

Postpartum ischemic stroke: a successful intravenous thrombolysis
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 18, 2021 Category: Neurology Source Type: research

Comment on “Paraneoplastic encephalomyelitis revealing burned-out seminoma”: confirmed case of anti-Kelch-like protein-11 encephalomyelitis
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 15, 2021 Category: Neurology Source Type: research

Clinical management of pediatric chordomas: a comprehensive review
AbstractChordomas are malignant tumors derived from remnants of the notochord. These are extremely rare in pediatric patients, accounting for approximately 5% of all chordomas, with most lesions occupying the cranium. Chordomas also can occupy all levels of the spine, demonstrating a broad spectrum of neurologic presentation. Optimal treatment aims for gross total resection with accompanying radiation therapy to prevent recurrence. Their aggressive and infiltrative nature makes clinical management challenging, involving multiple disciplines and close monitoring to ensure optimal outcomes. This comprehensive review aims to ...
Source: Acta Neurologica Belgica - October 14, 2021 Category: Neurology Source Type: research

Correlation of ATP7B gene mutations with clinical phenotype and radiological features in Indian Wilson disease patients
ConclusionsWD patients in eastern India have significant genotypic and phenotypic diversity. Statistical methods for binary classification show some early promise of detecting common mutations and suggest important covariates, but further studies with larger samples and screening of remaining exons are warranted for understanding the full genetic landscape of Wilson disease. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 13, 2021 Category: Neurology Source Type: research

Isolated intracranial hypertension following SARS-CoV-2 infection in an adolescent boy: a case report
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 11, 2021 Category: Neurology Source Type: research

Clinical and laboratory features of children with tremor: a single-center experience
ConclusionsMost of the cases with tremor can be diagnosed accurately by a detailed medical history, physical and neurological examination. Essential tremor is the most common type of tremor in children. Laboratory tests and imaging methods have limited additional yield in elucidating the etiology. Early recognition of tremor and related signs and symptoms in childhood is important for the detection and treatment of the possible underlying cause. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 7, 2021 Category: Neurology Source Type: research

Primary Sj ögren’s syndrome (pSS)-related cerebellar ataxia: a systematic review and meta-analysis
ConclusionsThe diagnostic approach to a patient with cerebellar ataxia of unknown etiology should include evaluation for an underlying pSS. A thorough history and clinical examination, antibody testing, brain MRI imaging and/or MRS of the cerebellum will assist in establishing the diagnosis. Setting up a joint neuro-rheumatology clinic can be valuable given that rheumatic and neurological diseases share comorbidities. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 5, 2021 Category: Neurology Source Type: research

Determinants of improvement in functional abilities in peripheral neuropathy patients undergoing rehabilitation: the role of Berg Balance Scale items
ConclusionsThe study shows that"unsupported standing" is an important determinant of results of ADL rehabilitation in PN patients and indicates that ability to stand without support for a fairly long time is an essential requirement to achieve with rehabilitation higher gain levels in functional abilities in PN patients. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 5, 2021 Category: Neurology Source Type: research

A new CHD2 variant: not only severe epilepsy —a case report
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 5, 2021 Category: Neurology Source Type: research

Determinants of improvement in functional abilities in peripheral neuropathy patients undergoing rehabilitation: the role of Berg Balance Scale items
ConclusionsThe study shows that"unsupported standing" is an important determinant of results of ADL rehabilitation in PN patients and indicates that ability to stand without support for a fairly long time is an essential requirement to achieve with rehabilitation higher gain levels in functional abilities in PN patients. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 5, 2021 Category: Neurology Source Type: research

A new CHD2 variant: not only severe epilepsy —a case report
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 5, 2021 Category: Neurology Source Type: research

Pediatric cerebral sinus venous thrombosis: clinical characterization of a Portuguese cohort
DiscussionIn this cohort, impairment of consciousness was the most frequent clinical presentation and infections were the most frequent risk factors. The outcome was mainly favorable, with most patients presenting none or mild disability and without recurrences on follow-up. Studies are needed to define the criteria for anticoagulation and its recommended duration in children. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 4, 2021 Category: Neurology Source Type: research

Comment on case series of COVID-19 in patients with myasthenia gravis: a single institution experience by Županić et al.
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 4, 2021 Category: Neurology Source Type: research

Late onset Aicardi –Goutières syndrome case report: a rare white matter disease mimicking as pseudo-enzyme deficiency
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 4, 2021 Category: Neurology Source Type: research

Comment on case series of COVID-19 in patients with myasthenia gravis: a single institution experience by Županić et al.
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 4, 2021 Category: Neurology Source Type: research

Pediatric cerebral sinus venous thrombosis: clinical characterization of a Portuguese cohort
DiscussionIn this cohort, impairment of consciousness was the most frequent clinical presentation and infections were the most frequent risk factors. The outcome was mainly favorable, with most patients presenting none or mild disability and without recurrences on follow-up. Studies are needed to define the criteria for anticoagulation and its recommended duration in children. (Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 4, 2021 Category: Neurology Source Type: research

Late onset Aicardi –Goutières syndrome case report: a rare white matter disease mimicking as pseudo-enzyme deficiency
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 4, 2021 Category: Neurology Source Type: research

Interaction between stroke severity and quality indicators of acute stroke care: a single-center retrospective analysis
AbstractIschemic stroke leads to substantial mortality and morbidity worldwide. Door-to-CT time, door-to-needle time (DNT), and door-to-groin time (DGT) are important quality indicators of stroke care. However, patient characteristics remain important determinants of outcome as well. In this single-center study, we investigated the interaction between these quality indicators and stroke severity regarding long-term functional outcome. All consecutive stroke patients treated at the ZOL stroke center, Genk, Belgium, between 2017 and 2020 were included in this retrospective observational study. Stroke severity was graded as &...
Source: Acta Neurologica Belgica - October 3, 2021 Category: Neurology Source Type: research

Neuralgic amyotrophy with isolated mononeuropathy of the musculocutaneous nerve: a problematic differential diagnosis of cervical radiculopathy
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 2, 2021 Category: Neurology Source Type: research

Guillain –Barré syndrome following Covid-19 immunization: a report of two cases
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - October 1, 2021 Category: Neurology Source Type: research

Rimmed vacuoles in late-onset LAMA2-related limb girdle muscular dystrophy
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

The importance of knowing the typical and atypical imaging findings of Wernicke encephalopathy
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

An uncommon case of thunderclap headache in a patient with Marfan syndrome
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Melkersson –Rosenthal syndrome: a cutaneous guide to a sinister neurological illness
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Foix –Chavany–Marie syndrome due to bilateral opercular ischemic lesions
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Late-onset of primary antiphospholipid syndrome: a case report
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Combination of acute hypertensive striatocapsular hemorrhage and mirror previous asymptomatic slit-like hemorrhage in a young patient: a new radiological clue for cerebral small vessel disease?
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Anti-NMDA receptor encephalitis after yellow fever vaccination: a case report
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Cocaine-induced multifocal leukoencephalopathy
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Intracranial epidural hematoma following lumbar puncture
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Paraneoplastic syndrome or immune-related adverse event? A case of rhomboencephalitis in a patient treated with Pembrolizumab
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Fisher syndrome as an immune-related adverse event after using pembrolizumab but not nivolumab
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research

Corpus callosum infarction in uncontrolled diabetes mellitus
(Source: Acta Neurologica Belgica)
Source: Acta Neurologica Belgica - September 16, 2021 Category: Neurology Source Type: research