Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis
In conclusion, the 2 different medications have the same efficacy and safety for treating cutaneous leishmaniasis. Pentavalent antimoniate intralesional infiltration treatment is safe, effective, and well tolerated with minimal side effects for Old-World cutaneous leishmaniasis.PMID:38682801 | DOI:10.2340/actadv.v104.35089 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2024 Category: Dermatology Authors: Michal Solomon Ayelet Ollech Felix Pavlotsky Aviv Barzilai Eli Schwartz Sharon Baum Nadav Astman Source Type: research
The Removal of Total Knee Arthroplasty From the Inpatient-Only List has Improved Patient Optimization
CONCLUSION: Outpatient TKA has increased considerably post-IPO removal. As this regulatory change has allowed older patients with increased comorbidities to undergo oTKA, the need for appropriate preoperative optimization has increased. The current data set demonstrates that surgeons have improved preoperative optimization efforts for select modifiable risk factors.PMID:38684134 | DOI:10.5435/JAAOS-D-22-01132 (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - April 29, 2024 Category: Orthopaedics Authors: Niall H Cochrane Billy I Kim William A Jiranek Thorsten M Seyler Michael P Bolognesi Sean P Ryan Source Type: research
From swamp to field: how genes from mangroves and its associates can enhance crop salinity tolerance
Mol Biol Rep. 2024 Apr 29;51(1):598. doi: 10.1007/s11033-024-09539-w.ABSTRACTSalinity stress is a critical challenge in crop production and requires innovative strategies to enhance the salt tolerance of plants. Insights from mangrove species, which are renowned for their adaptability to high-salinity environments, provides valuable genetic targets and resources for improving crops. A significant hurdle in salinity stress is the excessive uptake of sodium ions (Na+) by plant roots, causing disruptions in cellular balance, nutrient deficiencies, and hampered growth. Specific ion transporters and channels play crucial roles ...
Source: Molecular Biology Reports - April 29, 2024 Category: Molecular Biology Authors: Ganesan Govindan Prakash Harini Vinoth Alphonse Madasamy Parani Source Type: research
Achieving long-lived white circularly polarized luminescence from carbonized polymer dots < em > via < /em > phosphorescence resonance energy transfer
This study provides a universal strategy for the convenient and efficient preparation of CPD-based long-lived white CPL materials.PMID:38683641 | DOI:10.1039/d4cc00532e (Source: Chemical Communications)
Source: Chemical Communications - April 29, 2024 Category: Chemistry Authors: Feixiang Wang Yijie Wang Rui Guo Yushuang Wu Shengju Zhou Haibin Xiao Xiaofeng Sun Source Type: research
< em > Fusobacterium nucleatum < /em > -induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer
CONCLUSION: F. nucleatum can promote cancer progression through its inhibitory effect on butyric acid, via the AMPK signaling pathway.PMID:38681125 | PMC:PMC11045493 | DOI:10.3748/wjg.v30.i14.2018 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 29, 2024 Category: Gastroenterology Authors: Qi-Long Wu Xiao-Ting Fang Xin-Xin Wan Qing-Yong Ding Yan-Jun Zhang Ling Ji Yong-Liang Lou Xiang Li Source Type: research
Sodium-Glucose Cotransporter-2 Inhibitors and the Risk for Dialysis and Cardiovascular Disease in Patients With Stage 5 Chronic Kidney Disease
CONCLUSION: This emulated target trial showed that SGLT2i use was associated with a lower risk for dialysis, cardiovascular events, DKA, and AKI than no SGLT2i use in patients with T2D and stage 5 CKD.PRIMARY FUNDING SOURCE: National Health Research Institutes, Taiwan.PMID:38684099 | DOI:10.7326/M23-1874 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 29, 2024 Category: Internal Medicine Authors: Fu-Shun Yen Chii-Min Hwu Jia-Sin Liu Yi-Ling Wu Keong Chong Chih-Cheng Hsu Source Type: research
< em > Fusobacterium nucleatum < /em > -induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer
CONCLUSION: F. nucleatum can promote cancer progression through its inhibitory effect on butyric acid, via the AMPK signaling pathway.PMID:38681125 | PMC:PMC11045493 | DOI:10.3748/wjg.v30.i14.2018 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 29, 2024 Category: Gastroenterology Authors: Qi-Long Wu Xiao-Ting Fang Xin-Xin Wan Qing-Yong Ding Yan-Jun Zhang Ling Ji Yong-Liang Lou Xiang Li Source Type: research
Relationship Between Dietary Intakes and Elevated Diastolic Blood Pressure Among Children: A Cross-Sectional Study Using Wearable Devices
CONCLUSION: This study indicates that dietary intakes of high saturated fat, copper, and vitamin B12, but not parental blood pressure statuses, determine high diastolic blood pressure among children regardless of daily sodium intake. Early dietary consumption behavioral adaptation should be considered to prevent further hypertension in adulthood.PMID:38682517 | DOI:10.3233/SHTI240024 (Source: Studies in Health Technology and Informatics)
Source: Studies in Health Technology and Informatics - April 29, 2024 Category: Information Technology Authors: Kukiat Tudpor Panthicha Chinnakhot Montira Boonsorn Wiriyaporn Lomthaisong Worrameth Kareechum Charnyuth Sriphuwong Le Ke Nghiep Niruwan Turnbull Source Type: research
Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis
In conclusion, the 2 different medications have the same efficacy and safety for treating cutaneous leishmaniasis. Pentavalent antimoniate intralesional infiltration treatment is safe, effective, and well tolerated with minimal side effects for Old-World cutaneous leishmaniasis.PMID:38682801 | DOI:10.2340/actadv.v104.35089 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2024 Category: Dermatology Authors: Michal Solomon Ayelet Ollech Felix Pavlotsky Aviv Barzilai Eli Schwartz Sharon Baum Nadav Astman Source Type: research
Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis
In conclusion, the 2 different medications have the same efficacy and safety for treating cutaneous leishmaniasis. Pentavalent antimoniate intralesional infiltration treatment is safe, effective, and well tolerated with minimal side effects for Old-World cutaneous leishmaniasis.PMID:38682801 | DOI:10.2340/actadv.v104.35089 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - April 29, 2024 Category: Dermatology Authors: Michal Solomon Ayelet Ollech Felix Pavlotsky Aviv Barzilai Eli Schwartz Sharon Baum Nadav Astman Source Type: research
The Importance of Pseudo Thrombocytopenia Due to Platelet Cold Agglutination before Surgery, What Should We Do? A Case Report
Int J Hematol Oncol Stem Cell Res. 2024 Jan 1;18(1):100-103. doi: 10.18502/ijhoscr.v18i1.14749.ABSTRACTPlatelet cold agglutination (PCA) is a rare in-vitro phenomenon caused by Immunoglobulin M (IgM) autoantibodies, which results in Ethylenediaminetetraacetic Acid (EDTA) independent pseudo thrombocytopenia (PTCP). Its diagnosis is made based on the peripheral blood smear (PBS) examination and pre-test warming blood sample. Here, a case of PTCP secondary to PCA is presented. He was first admitted for pre-surgical tests but his platelet count was low. His blood was taken with EDTA and sodium citrate anticoagulant to rule pre...
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Mohammad Ghorbani Amin Solouki Farhang Soltani Amir Moayedpour Zahra Khoshnegah Source Type: research
Association of sodium –glucose cotransporter 2 inhibitors with changes in comprehensive geriatric assessment in elderly diabetic patients with heart failure: Data from MAGIC‐HF
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 29, 2024 Category: Cardiology Authors: Giuseppe Armentaro,
Velia Cassano,
Valentino Condoleo,
Marcello Magurno,
Marcello Divino,
Carlo Alberto Pastura,
Sofia Miceli,
Raffaele Maio,
Franco Arturi,
Marta Letizia Hribal,
Antonio Brunetti,
Giorgio Sesti,
Giuseppe Massimo Claudio Rosano Tags: Research Letter Source Type: research
Obese or lean: Whom to prescribe sodium –glucose cotransporter 2 inhibitors in heart failure with preserved ejection fraction?
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - April 29, 2024 Category: Cardiology Authors: Kseniya Halavina,
Philipp E. Bartko,
Christian Nitsche Tags: Invited Editorial Source Type: research
Cardioprotective Potential of Sodium-Glucose Co-Transporter-2 Inhibitors in Cancer Patients Treated With Anthracyclines: An Observational Study
This study aims to evaluate the safety and potential of SGLT2i for preventing cardiotoxicity in cancer patients, without pre-existing heart failure (HF), receiving anthracyclines therapy. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 29, 2024 Category: Cardiology Authors: Ayman R. Fath, Mostafa Aglan, Amro Aglan, Robert J. Chilton, Anatole Trakhtenbroit, Odaye A. Al-Shammary, Oduro Oppong-Nkrumah, Daniel J. Lenihan, Susan F. Dent, Prince Otchere Source Type: research
Antimicrobial action, cytotoxicity and erosive potential of hypochlorous acid obtained from an electrolytic device compared with sodium hypochlorite
ConclusionsIt is possible to conclude that HClO obtained from an electrolytic device presented high antimicrobial activity and low cytotoxicity in both tested concentrations. 500 ppm HClO did not display erosion and showed great cleaning ability.Clinical relevanceThe use of 500 ppm hypochlorous acid may reduce unfavorable behavior of sodium hypochlorite whilst maintaining its antimicrobial action. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 29, 2024 Category: Dentistry Source Type: research
