Step emulsification in microfluidic droplet generation: mechanisms and structures.
Abstract The droplet-based microfluidic techniques have been applied widely in functional material synthesis and biomedical information measurements, wherein step emulsification as an integrated system combines the advantages of homogeneity and throughput in monodisperse droplet formation. This paper reviews the mechanisms and classical structures of step emulsification. In terms of droplet formation mechanisms, we describe the droplet size and detachment regimes related to the microchannel geometry. Distinguished by droplet formation, microfluidic step emulsification driven by interfacial tension and centrifugal ...
Source: Chemical Communications - August 3, 2020 Category: Chemistry Authors: Shi Z, Lai X, Sun C, Zhang X, Zhang L, Pu Z, Wang R, Yu H, Li D Tags: Chem Commun (Camb) Source Type: research

Isolated zirconium centres captured from aqueous solution: the structure of zirconium mandelate revealed from NMR crystallography.
Abstract Zirconium tetramandelate (2-hydroxy-2-phenylacetate) has been used for selective gravimetric analysis of zirconium for over 70 years. Herein its crystal structure is reported from synchrotron powder X-ray diffraction and 13C solid-state NMR. The complex is a rare example of isolated zirconium cations, rather than the clusters prevalent in aqueous solutions. PMID: 32744549 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - August 3, 2020 Category: Chemistry Authors: Crosland JM, Corlett EK, Scapens D, Guillou N, Brown SP, Walton RI Tags: Chem Commun (Camb) Source Type: research

A DNAzyme cascade for amplified detection of intracellular miRNA.
Abstract Inspired by the natural enzyme cascade reaction, an artificial DNAzyme cascade system is developed for the amplified detection of intracellular miR-141. The results showed that the method enormously enhanced the readout of the fluorescence signal and achieved a femtomolar detection limit. PMID: 32744553 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - August 3, 2020 Category: Chemistry Authors: Wu Y, Li J, Quan K, Meng X, Yang X, Huang J, Wang K Tags: Chem Commun (Camb) Source Type: research

Oxacalix[4]arene-bridged pillar[5]arene dimers: syntheses, planar chirality and construction of chiral rotaxanes.
Abstract Conformationally fixed oxacalix[4]arene-bridged pillar[5]arene dimers comprising a pair of enantiomers and a meso isomer were designed and synthesized. Furthermore, chiral [2]rotaxanes and [3]rotaxanes were constructed. Two pairs of enantiomers for [2]rotaxanes, one pair of enantiomers and a meso isomer for [3]rotaxanes were found, respectively. PMID: 32744554 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - August 3, 2020 Category: Chemistry Authors: Wan K, Gao SC, Fang X, Xu MY, Yang Y, Xue M Tags: Chem Commun (Camb) Source Type: research

Metal-organic framework (MOF) materials as polymerization catalysts: a review and recent advances.
Abstract Synthetic polymers are ubiquitous across both the industrial and consumer segments of the world economy. Catalysts enable rapid, efficient, selective, and even stereoselective, formation of desired polymers from any of a host of candidate monomers. While numerous molecular catalysts have been shown to be effective for these reactions, separation of the catalysts from reaction products is typically difficult - a potentially problematic complication that suggests instead the use of heterogeneous catalysts. Many of the most effective heterogeneous catalysts, however, comprise supported collections of reactio...
Source: Chemical Communications - August 3, 2020 Category: Chemistry Authors: Goetjen TA, Liu J, Wu Y, Sui J, Zhang X, Hupp JT, Farha OK Tags: Chem Commun (Camb) Source Type: research

Non-canonical lipoproteins with programmable assembly and architecture.
This study demonstrates the promise of expanding the repertoire of PTMs for the development of nanomaterials with a unique assembly and function. PMID: 32734969 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Hossain MS, Maller C, Dai Y, Nangia S, Mozhdehi D Tags: Chem Commun (Camb) Source Type: research

Efficient, broadband self-trapped white-light emission from haloplumbate-based metal-organic frameworks.
Abstract Metal-organic frameworks (MOFs) with low-dimensional, deformable haloplumbate secondary building units (SBUs) are an emerging class of intrinsic white-light emitters combining advantageous properties of both MOFs and lead perovskites. Herein, we have successfully synthesized two MOFs with haloplumbate SBUs occupying an extremely high degree of structural strain with local zigzag Pb-X-Pb-X (X = Cl/Br) connectivity located in single-stranded helices. Thus, the electron-phonon coupling in the deformable SBUs affords intrinsic white-light emission and moderately high external photoluminescence quantum efficie...
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Song X, Peng C, Xu X, Yin J, Fei H Tags: Chem Commun (Camb) Source Type: research

Dynamic single-site polysulfide immobilization in long-range disorder Cu-MOFs.
We report the electrochemical amorphization of Cu3(BTC)2 MOFs in polysulfide electrolyte. We unveil the dynamic single-site polysulfide immobilization at the interconvertible Cu2+/Cu+ cation centres upon polysulfide adsorption and desorption, along with the reversible distortion of the Cu-O square planar unit. PMID: 32734980 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Sun J, Lu X, Wu KH, Hou J, Fang R, Hart JN, Zhu S, Chen V, Amal R, Wang DW Tags: Chem Commun (Camb) Source Type: research

Inorganic all-solid-state electrochromic devices with reversible color change between yellow-green and emerald green.
Abstract All-solid-state electrochromic devices with the structure of glass/ITO/WO3/Ta2O5/Li/V2O5/ITO were prepared by an evaporation method. Because of the use of a V2O5 complementary layer, the ECD can achieve obvious color change between yellow-green and emerald green with superior cycling performance up to 5000 cycles, indicating the great potential in smart window applications. PMID: 32734982 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Zhang X, Li W, Chen X, Zhao Y, Wang L, Chen M, Li Z, Li Y Tags: Chem Commun (Camb) Source Type: research

In situ AP-XPS analysis of a Pt thin-film sensor for highly sensitive H2 detection.
Abstract In situ ambient-pressure X-ray photoelectron spectroscopy (AP-XPS) combined with resistivity measurement was performed for a Pt thin-film H2 gas sensor. We experimentally demonstrate that the chemical state of the Pt surface changes under working conditions, and it directly links to the sensing performance. Moreover, the operating principle is discussed at the atomic scale. PMID: 32734986 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Toyoshima R, Tanaka T, Kato T, Uchida K, Kondoh H Tags: Chem Commun (Camb) Source Type: research

Near perfect head-to-head selectivity on the supramolecular photocyclodimerisation of 2-anthracenecarboxylate with self-organised gemini surfactant bilayers.
Abstract Silicificated self-organised crystalline bilayers of gemini surfactants were used as reaction templates for the supramolecular regioselective [4+4] photocyclodimerisation of 2-anthracenecarboxylate in water. A near perfect head-to-head cyclodimer selectivity, up to 97% at room temperature, was achieved with accelerated rate. PMID: 32734996 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Yospanya W, Nishijima M, Araki Y, Buffeteau T, Pouget E, Wada T, Oda R Tags: Chem Commun (Camb) Source Type: research

A dual-ion battery has two sides: the effect of ion-pairs.
Abstract There is mutual interference between the positive and negative electrodes in a dual-ion battery. In Li4Ti5O12/graphite batteries, strong ion-pairs between Li+ and anions may have a detrimental effect on intercalation at both sides: Li+ into Li4Ti5O12, and anions into graphite. PMID: 32735005 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Huang Y, Liang Z, Wang H Tags: Chem Commun (Camb) Source Type: research

Collective enantioselective total synthesis of (+)-sinensilactam A, (+)-lingzhilactone B and (-)-lingzhiol: divergent reactivity of styrene.
Abstract The collective total synthesis of (+)-sinensilactam A, (+)-lingzhilactone B, (+)-lingzhilactone C and (-)-lingzhiol has been accomplished from a common epoxide intermediate 9. Chemoselective epoxy opening with either an aryl or alkene moiety of styrene led to different carbon skeletons, which can be advanced to a divergent and concise total synthesis of four meroterpenoids. PMID: 32735006 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Zhang DW, Fan HL, Zhang W, Li CJ, Luo S, Qin HB Tags: Chem Commun (Camb) Source Type: research

Catalytic and enantioselective oxa-Piancatelli reaction using a chiral vanadium complex.
i H Abstract An enantioselective oxa-Piancatelli reaction was established for the first time using a chiral vanadium(v) catalyst. The dual Brønsted and Lewis acid properties of the vanadium catalyst afforded 4-hydroxycyclopent-2-enone derivatives in up to 90% yields and with 93 : 7 enantiomeric ratios, as well as>20 : 1 diastereomeric ratios. PMID: 32735309 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 31, 2020 Category: Chemistry Authors: Schober L, Sako M, Takizawa S, Gröger H, Sasai H Tags: Chem Commun (Camb) Source Type: research

Catalytic asymmetric aldehyde prenylation and application in the total synthesis of (-)-rosiridol and (-)-bifurcadiol.
Abstract Chiral phosphoric acid-catalyzed asymmetric aldehyde prenylation has been established using an α,α-dimethyl allyl boronic ester. The transformation provides expedient access to a wide array of aryl, heteroaryl, aryl-substituted alkenyl and primary and secondary aliphatic homoprenyl alcohols with excellent asymmetric induction. The utility of this asymmetric catalysis strategy has been demonstrated through a short and efficient total synthesis of the two natural products (-)-rosiridol and (-)-bifurcadiol. PMID: 32728678 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Zhang YL, Zhao ZN, Li WL, Li JJ, Kalita SJ, Schneider U, Huang YY Tags: Chem Commun (Camb) Source Type: research

A self-powered aptasensor using the capacitor-amplified signal of a photofuel cell and a portable digital multimeter readout.
Abstract A self-powered aptasensor for streptomycin detection was constructed with a photofuel cell combined with a capacitor and a digital multimeter. The sensitivity of the proposed sensor was 8.7 times of that without using a capacitor amplifier circuit. PMID: 32728679 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Chen Y, Ji W, Gao J, Yan K, Zhang J Tags: Chem Commun (Camb) Source Type: research

Cathodic electrogenerated chemiluminescence of tris(2,2'-bipyridine)ruthenium(ii) and peroxydisulfate at pure Ti3C2Tx MXene electrodes.
Abstract We demonstrate the first use of pure films of two-dimensional (2D) transition metal carbides and nitrides (Ti3C2Tx MXene) as an electrode material for electrogenerated chemiluminescence (ECL). The Ti3C2Tx MXene electrodes exhibited excellent electrochemical stability in the cathodic scan range and produced bright reductive-oxidation ECL using peroxydisulfate as a co-reactant with the tris(2,2'-bipyridine)ruthenium(ii) ([Ru(bpy)3]2+) luminophore. PMID: 32728680 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Zhang J, Kerr E, Usman KAS, Doeven EH, Francis PS, Henderson LC, Razal JM Tags: Chem Commun (Camb) Source Type: research

Near-infrared electrochemiluminescence in water through regioselective sulfonation of diaza [4] and [6]helicene dyes.
Abstract A series of water-soluble helicene dyes generating intense electrochemiluminescence (ECL) signal in physiological conditions is reported. Those species were prepared using diaza [4] and [6]helicenes as structural cores modified with sulfonate groups in various positions. Such groups improve their water solubility and can induce a red-shifted emission. Efficient ECL up to the near-infrared is achieved in water, demonstrating a viable strategy for the design of new near-infrared ECL dyes for bioassays and microscopy. PMID: 32728683 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Li H, Duwald R, Pascal S, Voci S, Besnard C, Bosson J, Bouffier L, Lacour J, Sojic N Tags: Chem Commun (Camb) Source Type: research

Red light-triggered photoreduction on a nucleic acid template.
okhir A Abstract Conjugate Sn(iv)(pyropheophorbide a)dichloride-(peptide nucleic acid) catalyzes reduction of azobenzene derivatives in the presence of complementary nucleic acid (NA) upon irridiation with red light (660 nm). This is the first red light-induced NA-templated photoreduction. It is highly sensitive to single mismatches in the NA-template and can detect down to 5 nM NAs. PMID: 32728684 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Dutta S, Rühle J, Schikora M, Deussner-Helfmann N, Heilemann M, Zatsepin T, Duchstein P, Zahn D, Knör G, Mokhir A Tags: Chem Commun (Camb) Source Type: research

Strong metal-support interactions enable highly transparent Pt-Mo2C counter electrodes of bifacial dye-sensitized solar cells.
Abstract Highly transparent and active Pt-Mo2C counter electrodes were successfully fabricated by the strong metal-support interaction, with high dispersity of Pt nanoclusters on Mo2C support, which endowed bifacial dye-sensitized solar cells with a rear-to-front efficiency ratio as high as 0.75. PMID: 32729584 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Wu C, Li R, Wang Y, Lu S, Lin J, Liu Y, Zhang X Tags: Chem Commun (Camb) Source Type: research

FnCas12a/crRNA assisted dumbbell-PCR detection of IsomiRs with terminal and inner sequence variants.
Abstract Herein, we report a FnCas12a/crRNA assisted Dumbbell-PCR method for the detection of isomiRs with double specificity and magnification. The single nucleotide variant of isomiRs in terminals and/or inner sequence could be discriminated by this strategy. Using this method, let-7a isomiRs in MCF-7 and MCF-7R cell lines were analyzed. PMID: 32729588 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Wang J, Bing T, Zhang N, Liu X, Shangguan D Tags: Chem Commun (Camb) Source Type: research

Cation- and anion-ordered rutile-type derivative LiTeO3(OH).
Abstract The first example of both cation- and anion-ordered rutile-type derivative LiTeO3(OH) (= HLiTeO4) has been discovered. LiTeO3(OH) belongs to a non-centrosymmetric space group P21. Both cations (Li+/Te6+) and anions (O2-/OH-) exhibit occupational ordering in LiTeO3(OH). PMID: 32729594 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Fujii K, Yoshida Y, Shan YJ, Tezuka K, Inaguma Y, Yashima M Tags: Chem Commun (Camb) Source Type: research

Full-color natural rubber latex with a photonic nanostructure composite.
Abstract As environmental problems increase, there is an urgent demand for new eco-friendly materials. Natural rubber latex (NRL) is a natural material extracted from rubber trees. But its dyeing process with chemical dyes might result in contamination and environmental degradation. Here, NRL is composited with a photonic crystal (PhC) structure by spin coating for the first time. The polymethyl methacrylate (PMMA) photonic nanostructure has been embedded into NRL to give it colors and provide it with optical functionalities. Colors of the composite could be designed and controlled by the sizes of the nanocolloids...
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Yan D, Qiu L, Meng Z, Shen Y, Xue M, Xu Z, Liu W Tags: Chem Commun (Camb) Source Type: research

Graphene encircled KFeSO4F cathode composite for high energy density potassium-ion batteries.
Abstract Herein, we report on a facile and novel synthesis and multifarious characterizations of the graphene wrapped KFeSO4F (KFSF@G) for the first time. The KFSF@G electrode exhibits admirable electrochemical performance with a high average operating potential of 3.55 V and high reversible discharge capacity of 111.51 mA h g-1. PMID: 32729858 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Dong J, Liao J, He X, Hu Q, Yu Y, Chen C Tags: Chem Commun (Camb) Source Type: research

A large room-temperature entropy change in a new hybrid ferroelastic with an unconventional bond-switching mechanism.
Abstract We showed a reversible bond-switching ferroelastic phase transition at near room temperature in a novel organic-inorganic hybrid, (Me3NNH2)2[Co(CN)6Na(H2O)], to afford a latent heat of 43.7 kJ kg-1 and a large entropy change of 146 J K-1 kg-1. PMID: 32729869 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 30, 2020 Category: Chemistry Authors: Xu WJ, Zeng Y, Yuan W, Zhang WX, Chen XM Tags: Chem Commun (Camb) Source Type: research

A sulfur-containing hetero-octulene: synthesis, host-guest properties, and transistor applications.
Abstract A heterocycloarene derivative (S-Octulene) possessing two sulfur atoms was conveniently synthesized through Bi(OTf)3-catalyzed cyclization from a macrocyclic tetramethoxyethenylated precursor. The physical properties of S-Octulene and its supramolecular host-guest interaction with C60 and C70 were investigated by fluorescence titration and 1H NMR. The solution-processed organic field-effect transistor (OFET) measurements demonstrated that S-Octulene behaved as a p-type semiconductor with a hole mobility exceeding 0.01 cm2 V-1 s-1. Our findings pave a new path to design novel heterocycloarenes for the deve...
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Yang L, Zhang N, Han Y, Zou Y, Qiao Y, Chang D, Zhao Y, Lu X, Wu J, Liu Y Tags: Chem Commun (Camb) Source Type: research

Amethyrin-type expanded porphyrins that display anti-aromatic character upon protonation.
Abstract The use of protonation to switch nonaromatic expanded porphyrins to their corresponding anti-aromatic forms has not been widely explored. Here, we show that free-base pyriamethyrin and dipyriamethyrin display nonaromatic character, as inferred from NMR spectroscopic analyses, their optical properties, and theoretical calculations. Addition of two protons extends the π - conjugation of these amethyrin analogues and yields formally anti-aromatic systems. PMID: 32724979 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Root HD, Mangel DN, Brewster JT, Zafar H, Samia A, Henkelman G, Sessler JL Tags: Chem Commun (Camb) Source Type: research

Facile preparation of a stable 3D host for lithium metal anodes.
Abstract A facile strategy was developed to stablize 3D hosts for lithium metal anodes in carbonate electrolytes, which enables lithium metal batteries with improved Coulombic efficiency (∼99%) and prolonged cycle lifespan (96% retention over 300 cycles) under the conditions of high areal loading (3 mA h cm-2) and low N/P ratio (4). PMID: 32724993 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Jiang Z, Jin L, Zeng Z, Xie J Tags: Chem Commun (Camb) Source Type: research

Novel triazole nucleoside analogues promote anticancer activity via both apoptosis and autophagy.
Abstract Novel nucleoside derivatives were developed using the strategy of "terminal N,N-dimethylation" to impart tertiary amines to a 1,2,4-triazole nucleoside. The obtained lead compounds displayed significantly improved anticancer activity with dual mechanisms of cell death via apoptosis and autophagy, offering a fresh perspective to searching for new anticancer candidates. PMID: 32724994 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Zhang Y, Liu X, Lin Y, Lian B, Lan W, Iovanna JL, Liu X, Peng L, Xia Y Tags: Chem Commun (Camb) Source Type: research

Engineering bimetal Cu, Co sites on 3D N-doped porous carbon nanosheets for enhanced oxygen reduction electrocatalysis.
Abstract 3D mesoporous Cu,Co-N-C nanosheet architectures are fabricated, showing greatly enhanced catalytic activity and stability in the ORR relative to their mono-metallic counterparts. Such superiority results from the synergistic interplay of their bimetallic sites, which can offer more accessible active sites and efficiently modulate their surface/interface electronic structures. PMID: 32724995 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Lu L, Liu Y, Fan J, Wang L, Lin Y, Xu D, Dai Z, Han M Tags: Chem Commun (Camb) Source Type: research

Correction: Cryptand-imidazolium supported total synthesis of the lasso peptide BI-32169 and its d-enantiomer.
Abstract Correction for 'Cryptand-imidazolium supported total synthesis of the lasso peptide BI-32169 and its d-enantiomer' by Ming Chen et al., Chem. Commun., 2019, 55, 3323-3326, DOI: 10.1039/C8CC10301A. PMID: 32724996 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Chen M, Wang S, Yu X Tags: Chem Commun (Camb) Source Type: research

Highly enantioselective addition of aliphatic aldehydes to 2-hydroxychalcone enabled by cooperative organocatalysts.
Abstract Herein, we developed an enantioselective addition of aliphatic aldehydes to 2-hydroxychalcone promoted by cooperative organocatalysts, giving access to hybrid flavonoids in excellent enantioselectivities. This reaction took advantage of cycloisomerization of 2-hydroxychalcone to form a transient flavylium under the irradiation of 24 W CFL, which was trapped by the in situ generated chiral enamine intermediate. The synergistic action of chiral phosphoric acid secured the excellent outcome of this reaction by ion-pairing with the transient flavylium. PMID: 32724997 [PubMed - as supplied by publisher] (...
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Hu J, Gao YQ, Xu D, Chen L, Wen W, Hou Y, Chen L, Xie W Tags: Chem Commun (Camb) Source Type: research

Natural-abundance 17O NMR spectroscopy of magnetically aligned lipid nanodiscs.
Abstract Natural-abundance 17O NMR experiments are used to investigate the hydrated water in magnetically aligned synthetic polymer based lipid-nanodiscs. Residual quadrupole couplings (RQCs) measured from the observed five 17O (central and satellite) transitions, and molecular dynamics simulations, are used to probe the ordering of water molecules across the lipid bilayer. PMID: 32724998 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Ravula T, Sahoo BR, Dai X, Ramamoorthy A Tags: Chem Commun (Camb) Source Type: research

Terminal-oxidant-free photocatalytic C-H alkylations of heteroarenes with alkylsilicates as alkyl radical precursors.
This study demonstrates that alkylsilicates can be used in photocatalytic radical chemistry under acidic conditions. PMID: 32725001 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Ikarashi G, Morofuji T, Kano N Tags: Chem Commun (Camb) Source Type: research

Nickel(ii)-catalyzed asymmetric thio-Claisen rearrangement of α-diazo pyrazoleamides with thioindoles.
Nickel(ii)-catalyzed asymmetric thio-Claisen rearrangement of α-diazo pyrazoleamides with thioindoles. Chem Commun (Camb). 2020 Jul 29;: Authors: Yang W, Lin X, Zhang Y, Cao W, Liu X, Feng X Abstract A nickel(ii) catalyzed enantioselective thio-Claisen rearrangement of α-diazo pyrazoleamides with thioindoles was realized with modified chiral N,N'-dioxide ligands, affording a variety of C3-substituted indole derivatives in high yields (up to 95%) with excellent enantioselectivities (up to 96% ee) under mild reaction conditions. A possible transition state model was proposed based on previou...
Source: Chemical Communications - July 29, 2020 Category: Chemistry Authors: Yang W, Lin X, Zhang Y, Cao W, Liu X, Feng X Tags: Chem Commun (Camb) Source Type: research

Selective and high yield transformation of glycerol to lactic acid using NNN pincer ruthenium catalysts.
Abstract The conversion of glycerol selectively to lactic acid has been accomplished in high yields (ca. 90%) by using a NNN pincer-Ru catalyst. DFT explains the role of the Ru-P bond and sterics in favoring the catalysis. PMID: 32720651 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: Dutta M, Das K, Prathapa SJ, Srivastava HK, Kumar A Tags: Chem Commun (Camb) Source Type: research

N,N-Diethyl-3-methylbenzamide (DEET) acts as a metal-organic framework synthesis solvent with phase-directing capabilities.
Abstract Metal-organic frameworks (MOFs) are generally synthesized in toxic formamide solvents. Greener solvents would lower production barriers and facilitate applications such as drug delivery. N,N-Diethyl-3-methylbenzamide (DEET), the most widely used insect repellent, is shown to serve this role. Furthermore, DEET-loaded MOFs can be leveraged in controlled-release insect repellent formulations. PMID: 32720652 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: Dodson RA, Kalenak AP, Du Bois DR, Gill-Ljunghammer SL, Matzger AJ Tags: Chem Commun (Camb) Source Type: research

Boron-hyperdoped silicon for the selective oxidative dehydrogenation of propane to propylene.
Abstract Boron containing catalysts have great potential in the oxidative dehydrogenation of propane. Herein, a series of 15, 25 and 42 at% boron-hyperdoped silicon catalysts synthesized by laser pyrolysis was studied. Boron-hyperdoped silicon samples showed>6 times higher propylene productivity than commercial h-BN at 450 °C. PMID: 32720653 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: Chen J, Rohani P, Karakalos SG, Lance MJ, Toops TJ, Swihart MT, Kyriakidou EA Tags: Chem Commun (Camb) Source Type: research

Efficient construction of a stable linear gene based on a TNA loop modified primer pair for gene delivery.
Abstract A terminal-closed linear gene with strong exonuclease resistance and serum stability was successfully constructed by polymerase chain reaction (PCR) with an α-l-threose nucleic acid (TNA) loop modified primer pair, which can be used as an efficient gene expression system in eukaryotic cells for gene delivery. PMID: 32720666 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: Lu X, Wu X, Wu T, Han L, Liu J, Ding B Tags: Chem Commun (Camb) Source Type: research

NIR-emitting squaraine J-aggregate nanosheets.
r F Abstract Click chemistry and Yamamoto coupling afforded an S-shaped π-scaffold composed of two directly connected dicyanomethylene-substituted squaraine dyes. This bis(squaraine) self-assembles into nanosheets in a cooperative self-assembly process, affording an absorption maximum at 886 nm and a fluorescence peak at 904 nm due to strong J-type exciton coupling. PMID: 32720667 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: Shen CA, Würthner F Tags: Chem Commun (Camb) Source Type: research

A 1-to-2 demultiplexer hybrid nanocarrier for cargo delivery and activation.
rtínez-Máñez R Abstract A biocomputing strategy implemented in hybrid nanocarriers for controlled cargo delivery is described. The nanodevice consists of enzyme-functionalized Janus Au-mesoporous silica nanoparticles, which behave as an electronic demultiplexer (DEMUX). The nanocarrier is capable of reading molecular information from the environment (lactose) and selecting one of two possible outputs (galactose production or 4-methylumbellilferone release and activation) depending on the presence of an addressing input (NAD+). PMID: 32720668 [PubMed - as supplied by publisher] (Source: Ch...
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: de Luis B, García-Fernández A, Llopis-Lorente A, Villalonga R, Sancenón F, Martínez-Máñez R Tags: Chem Commun (Camb) Source Type: research

A two-photon responsive naphthyl tagged p-hydroxyphenacyl based drug delivery system: uncaging of anti-cancer drug in the phototherapeutic window with real-time monitoring.
We report a two-photon responsive drug delivery system (DDS), namely, p-hydroxyphenacyl-naphthalene-chlorambucil (pHP-Naph-Cbl), having a two-photon absorption (TPA) cross-section of ≥20 GM in the phototherapeutic window (700 nm). Our DDS exhibited both AIE and ESIPT phenomena, which were utilized for the real-time monitoring of anti-cancer drug release. PMID: 32720950 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: Singh AK, Kundu M, Roy S, Roy B, Shah SS, Nair AV, Pal B, Mondal M, Singh NDP Tags: Chem Commun (Camb) Source Type: research

(NH4)3[B(OH)3]2(COOH)3: a graphite-like UV nonlinear optical material with a large birefringence via structural optimization.
Abstract A novel noncentrosymmetric (NCS) metal-free formic-borate, (NH4)3[B(OH)3]2(COOH)3, has been discovered, which exhibits an infrequent graphite-like structure. The alliance of two types of π-conjugated planar anions BO33- and COOH- produced an optimized layered structure to maximize the anisotropic polarizability, resulting in an extremely large birefringence (0.156@546 nm), larger than that of the classical commercial UV birefringent material α-BBO (0.122@546 nm). This strategy that structural optimization could enhance birefringence will guide the discovery of large birefringence materials, espec...
Source: Chemical Communications - July 28, 2020 Category: Chemistry Authors: Deng Y, Wang L, Ge Y, Huang L, Gao D, Bi J, Zou G Tags: Chem Commun (Camb) Source Type: research

Enhanced ionic photocurrent generation through a homogeneous graphene derivative composite membrane.
We report an enhanced light-harvesting two-dimensional nanofluidic system based on a homogeneous graphene derivative nanocomposite membrane, and demonstrate an enhanced proton flow upon asymmetric light illumination. The maximum photocurrent is achieved by appropriately sandwiching graphene oxide quantum dots for adjusting the interlayer spacing of the membrane and reinforcing the membrane potential. PMID: 32716018 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 27, 2020 Category: Chemistry Authors: Zhang Y, Zhao G, Zhu H, Jiang L Tags: Chem Commun (Camb) Source Type: research

Taking advantage of the aromatisation of 7-diethylamino-4-methyl-3,4-dihydrocoumarin in the fluorescence sensing of superoxide anion.
Abstract The aromatisation of 7-diethylamino-3,4-dihydrocoumarin provides an alternative fluorescent probing technique to selectively detect the concentration of superoxide anion in solution. In addition, we reported the advantage of evaluating O2˙- sensing probes in anhydrous DMSO instead of in aqueous buffers when using KO2 as the surrogate of O2˙-. PMID: 32716414 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 27, 2020 Category: Chemistry Authors: Wang Y, Han J, Xu Y, Gao Y, Wen H, Cui H Tags: Chem Commun (Camb) Source Type: research

Structural evidence for a reaction intermediate mimic in the active site of a sulfite dehydrogenase.
Abstract By combining X-ray crystallography, electron paramagnetic resonance techniques and density functional theory-based modelling, we provide evidence for a direct coordination of the product analogue, phosphate, to the molybdenum active site of a sulfite dehydrogenase. This interaction is mimicking the still experimentally uncharacterized reaction intermediate proposed to arise during the catalytic cycle of this class of enzymes. This work opens new perspectives for further deciphering the reaction mechanism of this nearly ubiquitous class of oxidoreductases. PMID: 32716419 [PubMed - as supplied by publi...
Source: Chemical Communications - July 27, 2020 Category: Chemistry Authors: Djeghader A, Rossotti M, Abdulkarim S, Biaso F, Gerbaud G, Nitschke W, Schoepp-Cothenet B, Soulimane T, Grimaldi S Tags: Chem Commun (Camb) Source Type: research

A structurally precise AgxAu25-x nanocluster based cancer theranostic platform with tri-targeting/in situ O2-generation/aggregation enhanced fluorescence imaging/photothermal-photodynamic therapies.
Abstract The photothermal and photodynamic performances of structurally precise oil-soluble AgxAu25-x (x ≤ 13) nanoclusters were first explored and they were solubilized into new assemblies to form a versatile cancer theranostic platform with tri-targeting/in situ O2-generation/aggregation enhanced fluorescence imaging/photothermal-photodynamic therapy effects, which will provide an important reference for precision theranostics at the atomic level in future. PMID: 32716421 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 27, 2020 Category: Chemistry Authors: Yang Y, Zhou Y, Wang S, Wang X, Liu X, Xie A, Shen Y, Zhu M Tags: Chem Commun (Camb) Source Type: research

Iron Fenton oxidation of 2'-deoxyguanosine in physiological bicarbonate buffer yields products consistent with the reactive oxygen species carbonate radical anion not the hydroxyl radical.
Abstract Product analysis from the iron Fenton oxidation of 2'-deoxyguanosine found reactions in bicarbonate buffer yield 8-oxo-2'-deoxyguanosine and spiroiminodihyantoin consistent with CO3˙-. Reactions in phosphate buffer furnished high yields of sugar oxidation products consistent with HO˙. These observations change the view of DNA oxidation products from the iron-Fenton reaction. PMID: 32716425 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 27, 2020 Category: Chemistry Authors: Fleming AM, Burrows CJ Tags: Chem Commun (Camb) Source Type: research

Guidelines for designing highly concentrated electrolytes for low temperature applications.
min J Abstract The redefinition of the commonly named "water-in-salt" clarifies the operating temperatures of the state-of-the-art LiTFSI-based aqueous solutions. An in-depth study shows its mismatch for low temperature applications. In contrast, the recommended strategy is to design an electrolyte with an invariant composition, as exemplified by the eutectic water/LiNO3 that is able to electrochemically cycle down to -23 °C. PMID: 32716427 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 27, 2020 Category: Chemistry Authors: Ah-Lung G, Flamme B, Ghamouss F, Maréchal M, Jacquemin J Tags: Chem Commun (Camb) Source Type: research

The [2+2] cycloaddition product of perhalogenated cyclopentadienyl cations: structural characterization of salts of the [C10Cl10]2+ and [C10Br10]2+ dications.
i M Abstract Instead of monomeric cyclopentadienyl cations, the low-temperature reaction of hexachloro- and hexabromocyclo-pentadiene (C5Cl6 and C5Br6) with powerful Lewis acids SbF5 and AsF5 in SO2ClF yields salts of perhalogenated dications [C10Cl10][Sb3F16]2 and [C10Br10][As2F11]2 which are characterized via single crystal X-ray diffraction and NMR spectroscopy. Additionally, this reactivity is rationalized by quantum-chemical calculations. PMID: 32716428 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 27, 2020 Category: Chemistry Authors: Rupf SM, Pröhm P, Malischewski M Tags: Chem Commun (Camb) Source Type: research