Ruthenium-catalyzed selective α-deuteration of aliphatic nitriles using D2O.
Ruthenium-catalyzed selective α-deuteration of aliphatic nitriles using D2O. Chem Commun (Camb). 2018 Jul 19;: Authors: Krishnakumar V, Gunanathan C Abstract Selective catalytic α-deuteration of aliphatic nitriles using deuterium oxide as a deuterium source is reported. A PNP-ruthenium pincer complex catalyzed the α-deuteration of aliphatic nitriles including acetonitrile. Efficient deuteration occurred with a low catalyst load (0.2 to 0.5 mol%) and under mild conditions. A [2+2] cycloadduct formation from nitrile functionality and a deprotonated catalytic intermediate, followed by a...
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Krishnakumar V, Gunanathan C Tags: Chem Commun (Camb) Source Type: research

A neptunium(v)-mediated interwoven transuranium-rotaxane network incorporating a mechanically interlocked [c2]daisy chain unit.
Abstract As an extension of actinide-rotaxane complexes from uranium to transuranium, we report the first crystal structure of a neptunium-rotaxane complex, NRCP-1, in which an interwoven neptunium(v)-rotaxane coordination network incorporating a mechanically-interlocked [c2]daisy chain unit is promoted via the simultaneous coordination of cucurbituril (CB6) and axle molecules in [2]pseudorotaxane to NpV. PMID: 30022209 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Mei L, Xu C, Wu QY, Hu KQ, Yuan LY, Chen J, Xiao CL, Wang SA, Chai ZF, Shi WQ Tags: Chem Commun (Camb) Source Type: research

Maltodextrin recognition by a macrocyclic synthetic lectin.
Abstract A monocyclic "temple" synthetic lectin, with extended electron-rich aromatic surfaces, shows enhanced affinities for carbohydrates in water. The methoxy substituents favour binding to α-linked maltodextrins, against the all-equatorial substrates normally favoured by this family of receptors. PMID: 30022217 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Stewart P, Renney CM, Mooibroek TJ, Ferheen S, Davis AP Tags: Chem Commun (Camb) Source Type: research

Copper-mediated intramolecular aminofluorination of 1,3-dienes by using nucleophilic fluorine reagents.
Abstract A copper-mediated intramolecular aminofluorination of 1,3-dienes is disclosed, in which both AgF and Et3N·3HF can be used as the fluorine source. This protocol provides a variety of pyrrolidines bearing allylic fluorides with excellent regioselectivities and good diastereoselectivities. PMID: 30023991 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Zhang Z, Chen P, Liu G Tags: Chem Commun (Camb) Source Type: research

Supramolecular nanoparticles based on β-CD modified hyaluronic acid for DNA encapsulation and controlled release.
Supramolecular nanoparticles based on β-CD modified hyaluronic acid for DNA encapsulation and controlled release. Chem Commun (Camb). 2018 Jul 19;: Authors: Yang Y, Jia X, Zhang YM, Li N, Liu Y Abstract Supramolecular nanoparticles composed of doubly positively charged adamantane (ADA2+) and β-CD modified hyaluronic acid (HACD) were constructed. When the ester group in ADA2+ was hydrolyzed to a carboxyl group, the quaternary ammonium chain with a positive charge in ADA2+ converted to a "zwitterionic" structure, and the controlled binding and release of pDNA was realized. PMID:...
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Yang Y, Jia X, Zhang YM, Li N, Liu Y Tags: Chem Commun (Camb) Source Type: research

Novel D-A-D based near-infrared probes for the detection of β-amyloid and Tau fibrils in Alzheimer's disease.
Novel D-A-D based near-infrared probes for the detection of β-amyloid and Tau fibrils in Alzheimer's disease. Chem Commun (Camb). 2018 Jul 19;: Authors: Li Y, Wang K, Zhou K, Guo W, Dai B, Liang Y, Dai J, Cui M Abstract Novel D-π-A-π-D probes were investigated for the detection of Aβ plaques and NFTs. The probes displayed remarkable optical properties, and DADNIR-2 possessed high affinity towards Tau and Aβ aggregates (Kd = 0.41 nM and 1.04 nM, respectively) with certain selectivity. DADNIR-2 could penetrate the BBB and label Aβ plaques in vivo. PMID: 30023996 [PubMed - ...
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Li Y, Wang K, Zhou K, Guo W, Dai B, Liang Y, Dai J, Cui M Tags: Chem Commun (Camb) Source Type: research

Chiral supramolecular coordination cages as high-performance inhibitors against amyloid- β aggregation.
Chiral supramolecular coordination cages as high-performance inhibitors against amyloid-β aggregation. Chem Commun (Camb). 2018 Jul 19;: Authors: Bao LY, Hao SJ, Xi SF, Yan X, Zhang HX, Shen R, Gu ZG Abstract Four pairs of chiral supramolecular coordination cages were facilely synthesized, and they could efficiently inhibit amyloid-β (Aβ) aggregation with a high inhibition rate of 0.64-0.86. This research provides a new perspective on the design of chiral Aβ inhibitors using supramolecular metal-organic cages. PMID: 30024578 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Bao LY, Hao SJ, Xi SF, Yan X, Zhang HX, Shen R, Gu ZG Tags: Chem Commun (Camb) Source Type: research

Csp3-H bond functionalization of amines via tunable iminium ions: divergent synthesis of trifluoromethylated arylamines.
Abstract A series of tunable iminium ions, generated in situ by the condensation of 4-trifluoromethyl-p-quinols with cyclic amines, can lead to the divergent synthesis of trifluoromethylated arylamines in a single step via redox-neutral isomerization. The direct α- and β-functionalization of saturated amines can be achieved regioselectively under mild conditions. PMID: 30024583 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 19, 2018 Category: Chemistry Authors: Shi L, Wang M, Pan L, Li Y, Liu Q Tags: Chem Commun (Camb) Source Type: research

Evidence for the synthesis of an unusual high spin (S = 7/2) [Cu-3Fe-4S] cluster in the radical-SAM enzyme RSAD2 (viperin).
Abstract We demonstrate the synthesis and spectroscopic characterization of an unusual high spin (S = 7/2) [Cu-3Fe-4S] cluster in a member of the radical-SAM enzymes. This is the first step in using synthetic [Me-3Fe-4S] clusters for obtaining new insight into the mechanism of radical-SAM catalysis. PMID: 30019036 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Honarmand Ebrahimi K, Silveira C, Todorovic S Tags: Chem Commun (Camb) Source Type: research

Enhancement of photoredox catalytic properties of porphyrinic metal-organic frameworks based on titanium incorporation via post-synthetic modification.
Abstract Porphyrinic metal-organic frameworks could be endowed with greatly improved photocatalytic activity for both oxidation and reduction, based on the incorporation of titanium via a facile cation-exchange strategy. PMID: 30019039 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: He J, Zhang Y, He J, Zeng X, Hou X, Long Z Tags: Chem Commun (Camb) Source Type: research

Synthesis of amphiphilic graphitic silver nanoparticles with inherent internal standards: an efficient strategy for reliable quantitative SERS analysis in common fluids.
Abstract An efficient strategy for reliable quantitative SERS analysis in common fluids was proposed by amphiphilic functionalization of graphitic silver nanoparticles with inherent internal standards by azides, and has the merits of high accuracy, enhanced dispersity and outstanding stability in fluids. PMID: 30019040 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Song ZL, Dai X, Li M, Song Z, Chen Z, Luo X Tags: Chem Commun (Camb) Source Type: research

Two-dimensional tellurium nanosheets for photoacoustic imaging-guided photodynamic therapy.
We report the synthesis of two-dimensional Te nanosheets through a facile liquid exfoliation method. The as-synthesized Te nanosheets can produce reactive oxygen species under light irradiation and show high photoacoustic imaging performance due to their strong near-infrared absorbance, and can be engineered as a nanoplatform for simultaneous photoacoustic imaging and photodynamic therapy. PMID: 30019046 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Lin Y, Wu Y, Wang R, Tao G, Luo PF, Lin X, Huang G, Li J, Yang HH Tags: Chem Commun (Camb) Source Type: research

Schiff-base coordination complexes with plutonium(iv) and cerium(iv).
Abstract PuL2 and CeL2 (L = N,N'-bis[(4,4'-diethylamino)salicylidene]-1,2-phenylenediamine) have been synthesized, and characterized by single crystal X-ray diffraction, UV/vis/NIR spectroscopy, and cyclic voltammetry. These studies reveal the enhanced stabilization of Pu(iv) versus Ce(iv) with this Schiff base, and quasi-reversible redox behaviour only with the plutonium complex. PMID: 30019711 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Klamm BE, Windorff CJ, Marsh ML, Meeker DS, Albrecht-Schmitt TE Tags: Chem Commun (Camb) Source Type: research

Iodine catalyzed reduction of quinolines under mild reaction conditions.
Abstract A reduction of quinolines to synthetically versatile tetrahydroquinoline molecules with I2 and HBpin is described. In the presence of iodine (20 mol%) as a catalyst, reduction of quinolines and other N-heteroarenes proceeded readily with hydroboranes as the reducing reagents. The broad functional-group tolerance, good yields and mild reaction conditions imply high practical utility. PMID: 30019712 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Yang CH, Chen X, Li H, Wei W, Yang Z, Chang J Tags: Chem Commun (Camb) Source Type: research

Silver-catalyzed stereoselective formation of glycosides using glycosyl ynenoates as donors.
Abstract A silver-catalyzed glycosylation reaction employing readily accessible and stable glycosyl ynenoates is developed. This reaction is mostly high yielding and exhibits varying levels of stereoinversion at the anomeric position. Compared to established and versatile Yu's gold catalysis, this chemistry features the use of substantially cheaper AgNTf2. PMID: 30019713 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Dong X, Chen L, Zheng Z, Ma X, Luo Z, Zhang L Tags: Chem Commun (Camb) Source Type: research

Tailored transition metal-doped nickel phosphide nanoparticles for the electrochemical oxygen evolution reaction (OER).
Abstract Foreign transition metals are doped into the hexagonal nickel phosphide structure through a simple and facile bottom-up wet-chemical synthesis process via stabilization with oleylamine, trioctylphosphine (TOP), and trioctylphosphine oxide (TOPO): the as-prepared transition metal-doped nickel phosphide nanoparticles show a high level of doping but create no significant distortion of the crystal structure and morphology against pristine nickel phosphide nanoparticles, which exhibit excellent activity in the electrochemical oxygen evolution reaction (OER), having overpotential as small as 330 mV at 20 mA cm-...
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Man HW, Tsang CS, Li MM, Mo J, Huang B, Lee LYS, Leung YC, Wong KY, Tsang SCE Tags: Chem Commun (Camb) Source Type: research

"Calix[4]-box" cages promote the formation of amide bonds in water in the absence of coupling reagents.
"Calix[4]-box" cages promote the formation of amide bonds in water in the absence of coupling reagents. Chem Commun (Camb). 2018 Jul 18;: Authors: Feng WX, Dai L, Zheng SP, van der Lee A, Su CY, Barboiu M Abstract The present work shows that encapsulation can be used to promote amide bond formation in water under mild conditions, in the absence of carbodiimide coupling agents. PMID: 30019715 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Feng WX, Dai L, Zheng SP, van der Lee A, Su CY, Barboiu M Tags: Chem Commun (Camb) Source Type: research

Remote activation of nanoparticulate biomimetic activity by light triggered pH-jump.
Abstract Herein, we report a facile, efficient and versatile method for the photo-regulation of pH-dependent activities of artificial enzymes by incorporating flash photolysis reagents. Under light excitation, a persistent pH shift is achieved by proton release from photosensitive 2-nitrobenzaldehyde. Following such change, the controlled activation of oxidase-like activity of nanoceria is successfully demonstrated. PMID: 30020279 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Wang X, Gong A, Luo W, Wang H, Lin C, Liu XY, Lin Y Tags: Chem Commun (Camb) Source Type: research

Structural differences between toxic and nontoxic HypF-N oligomers.
Abstract We have studied two misfolded oligomeric forms of the protein HypF-N, which show similar morphologies but very different toxicities. We measured over 80 intermolecular distance-dependent parameters for each oligomer type using FRET, in conjunction with solution- and solid-state NMR and other biophysical techniques. The results indicate that the formation of a highly organised hydrogen bonded core in the toxic oligomers results in the exposure of a larger number of hydrophobic residues than in the nontoxic species, causing the former to form aberrant interactions with cellular components. PMID: 300202...
Source: Chemical Communications - July 18, 2018 Category: Chemistry Authors: Capitini C, Patel JR, Natalello A, D'Andrea C, Relini A, Jarvis JA, Birolo L, Peduzzo A, Vendruscolo M, Matteini P, Dobson CM, De Simone A, Chiti F Tags: Chem Commun (Camb) Source Type: research

A plausible model correlates prebiotic peptide synthesis with the primordial genetic code.
Abstract Aminoacyladenylates (5'-aa-AMPs) are key intermediates in peptide synthesis. Here we report analogs of 5'-aa-AMPs, namely nucleotide amidates (aa-N-NMPs), obtained under Hadean conditions. Significantly, dipeptides were detected from the above reactions and their yields varied with different nucleosides through the formation of different aa-N-NMPs. This model provides both prebiotic peptides and the primordial version of the genetic code through reactions that occurred under potentially prebiotic conditions. PMID: 30014068 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 17, 2018 Category: Chemistry Authors: Ying J, Fu S, Li X, Feng L, Xu P, Liu Y, Gao X, Zhao Y Tags: Chem Commun (Camb) Source Type: research

Tailoring the components and morphology of discharge products towards highly rechargeable Li-CO/CO2 batteries.
Abstract A new non-aqueous Li-CO/CO2 battery with the main discharge products being Li2CO3 and carbon is introduced for the first time. Our findings demonstrate that with the addition of CO, the components and morphology of the discharge products are skillfully tailored, becoming more uniform, with poorer crystallinity and better conductivity. Thanks to these features, the utilization of a cathode in the Li-CO/CO2 battery system is increased and the discharge products are more easily decomposed. These positive effects caused by CO endow the Li-CO/CO2 battery with enhanced electrochemical performances. PMID: 3...
Source: Chemical Communications - July 17, 2018 Category: Chemistry Authors: Ma S, Yao H, Lei D, Guo X, Lu Y, Liu Q, Li Z Tags: Chem Commun (Camb) Source Type: research

Unexpectedly efficient SO2 capture and conversion to sulfur in novel imidazole-based deep eutectic solvents.
Abstract An innovative strategy for sustainable SO2 capture and conversion in novel imidazole-based deep eutectic solvents (DESs) is demonstrated in this work. These DESs exhibit an extremely high SO2 loading capacity (up to 1.39 g g-1) and excellent reversibility (15 recycles). The absorbed SO2 can be rapidly converted in situ to sulphur (up to 99% conversion) in the presence of H2S at room temperature without any additives. PMID: 30014083 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 17, 2018 Category: Chemistry Authors: Zhao T, Liang J, Zhang Y, Wu Y, Hu X Tags: Chem Commun (Camb) Source Type: research

Palladium-catalyzed C(carbonyl)-C bond cleavage of amides: a facile access to phenylcarbamate derivatives with alcohols.
Abstract A sulfur-containing auxiliary enabled palladium-catalyzed C(carbonyl)-C bond activation of amides was reported to form phenylcarbamate derivatives with alcohols. Both alkyl and benzyl alcohols could be employed well with yields up to 85%. Derivations from phenylcarbamates to ureas and thiocarbamates illustrated the potential applications of this sequential C-C cleavage/C-O coupling reaction. PMID: 30015335 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 17, 2018 Category: Chemistry Authors: Yan X, Sun H, Xiang H, Yu DG, Luo D, Zhou X Tags: Chem Commun (Camb) Source Type: research

Sensitive and label-free discrimination of 5-hydroxymethylcytosine and 5-methylcytosine in DNA by ligation-mediated rolling circle amplification.
Abstract We develop a label-free fluorescence method for sensitive discrimination of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) based on the specific oxidation of 5hmC to 5-formylcytosine (5fC) and the subsequent conversion to uracil (U) in combination with ligation-mediated rolling circle amplification (RCA). This method exhibits high sensitivity with a detection limit of as low as 34.8 fM. It can discriminate as low as the 0.01% 5hmC level from the mixture, and exhibits good performance in serum sample analysis as well. PMID: 30015347 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 17, 2018 Category: Chemistry Authors: Wang ZY, Wang M, Zhang Y, Zhang CY Tags: Chem Commun (Camb) Source Type: research

Enhancement in RNase H activity of a DNA/RNA hybrid duplex using artificial cationic oligopeptides.
This study assessed the effects of artificial cationic oligopeptides on a DNA/RNA hybrid duplex. An oligopeptide containing the octamer of l-2,4-diaminobutyric acid (Dab8) was found to enhance both the RNase A resistance and RNase H activity of the DNA/RNA hybrid, which are important for developing nucleic acid drugs. PMID: 30009294 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Hara RI, Maeda Y, Fujimaki H, Wada T Tags: Chem Commun (Camb) Source Type: research

Room temperature carbon monoxide oxidation based on two-dimensional gold-loaded mesoporous iron oxide nanoflakes.
Abstract In this work, we fabricate a highly effective catalyst for carbon monoxide oxidation based on gold-loaded mesoporous maghemite nanoflakes which exhibit nearly 100% CO conversion and a very high specific activity of 8.41 molCO gAu-1 h-1 at room temperature. Such excellent catalytic activity is promoted by the synergistic cooperation of their high surface area, large pore volume, and mesoporous structure. PMID: 30009299 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Kaneti YV, Tanaka S, Jikihara Y, Nakayama T, Bando Y, Haruta M, Hossain MSA, Golberg D, Yamauchi Y Tags: Chem Commun (Camb) Source Type: research

Molecular adaptation in supramolecular self-assembly: brickwall-type phases of indacene-tetrone on silver surfaces.
Abstract The supramolecular self-assembly of s-indacene-1,3,5,7(2H,6H)-tetrone (INDO4) on Ag(111), Ag(100) and Ag(110) surfaces was studied using scanning tunneling microscopy (STM). Four similar brickwall-type phases were found and in two of them the molecules appeared with distinct alternating contrast. The origin of this effect is discussed in terms of molecular adaptation. PMID: 30009302 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Kalashnyk N, Dumur F, Gigmes D, Clair S Tags: Chem Commun (Camb) Source Type: research

[RuII(tpy)(bpy)Cl]+-Catalyzed reduction of carbon dioxide. Mechanistic insights by carbon-13 kinetic isotope effects.
Abstract In this work, we examine the use of competitive 13C kinetic isotope effects (13C KIEs) on CO2 reduction reactions that produce CO and formic acid as a means to formulate reaction mechanisms. The findings reported here mark a further advancement in the combined 13C KIE measurements and theoretical calculations methodology for probing CO2 conversion reactions. PMID: 30009305 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Schneider TW, Hren MT, Ertem MZ, Angeles-Boza AM Tags: Chem Commun (Camb) Source Type: research

ESIPT-based fluorescence probe for the rapid detection of hypochlorite (HOCl/ClO-).
Abstract ESIPT-based fluorescence probes are emerging as an attractive tool for the detection of biologically relevant analytes owing to their unique photophysical properties. In this work, we have developed an ESIPT-based fluorescence probe (TCBT-OMe) for the detection of HClO/ClO- through the attachment of a bioorthogonal dimethylthiocarbamate linker. TCBT-OMe was shown to rapidly detect HClO/ClO- (30 min to produce a fluorescence response. Test strips containing TCBT-OMe were prepared and were demonstrated as an effective way to detect HClO/ClO- in water. Furthermore, TCBT-OMe was shown to detect exogenously ad...
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Wu L, Yang Q, Liu L, Sedgwick AC, Cresswell AJ, Bull SD, Huang C, James TD Tags: Chem Commun (Camb) Source Type: research

A smart photosensitizer based on a red emitting solution processable porous polymer: generation of reactive oxygen species.
Abstract A novel approach for the fabrication of a solution processable conjugated porous organic polymer (CzBDP) involving a flexible core composed of carbazole and boron dipyrromethene was developed. The red emitting soluble polymer was found to be an excellent probe for the generation of both singlet oxygen and superoxide anion radicals under visible light irradiation. PMID: 30010163 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Bandyopadhyay S, Kundu S, Giri A, Patra A Tags: Chem Commun (Camb) Source Type: research

Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS).
Abstract Through utilizing the depth penetration capabilities of SESORS, multiplexed imaging and classification of three singleplex nanotags and a triplex of nanotags within breast cancer tumour models is reported for the first time through depths of 10 mm using a handheld SORS instrument. PMID: 30010164 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Nicolson F, Jamieson LE, Mabbott S, Plakas K, Shand NC, Detty MR, Graham D, Faulds K Tags: Chem Commun (Camb) Source Type: research

ALKBH5-induced demethylation of mono- and dimethylated adenosine.
l T Abstract RNA contains methylated A-base derivatives. A methylation to m6A and then demethylation regulate homeostasis in mRNA. It is assumed that m6A is mainly demethylated by the α-ketoglutarate dependent oxidase ALKBH5. Here we show that ALKBH5 also demethylates the dimethylated adenosine m62A, which is a non-canonical base present in ribosomal RNA. PMID: 30010678 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: Ensfelder TT, Kurz MQ, Iwan K, Geiger S, Matheisl S, Müller M, Beckmann R, Carell T Tags: Chem Commun (Camb) Source Type: research

UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids.
Abstract The regiospecific glycosylation of pentacyclic triterpenoids by UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, is highlighted. UGT73F17 exhibited strict substrate specificity toward the carboxyl group at C-30/C-29 of pentacyclic triterpenoids, and showed high promiscuity to sugar donors. UGT73F17 represents the first identified triterpenoid 30/29-O-glycosyltransferase, and could be used as an effective biocatalyst to synthesize glycosyl ester saponins. PMID: 30010690 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 16, 2018 Category: Chemistry Authors: He J, Chen K, Hu ZM, Li K, Song W, Yu LY, Leung CH, Ma DL, Qiao X, Ye M Tags: Chem Commun (Camb) Source Type: research

Electrochemical N2 fixation to NH3 under ambient conditions: Mo2N nanorod as a highly efficient and selective catalyst.
Abstract A highly attractive, but still a key challenge, is the development of earth-abundant electrocatalysts for efficient NH3 electrosynthesis via the N2 reduction reaction (NRR). In this communication, we report the development of a Mo2N nanorod as a highly efficient and selective NRR electrocatalyst for artificial N2 fixation in acidic electrolytes under ambient conditions. In 0.1 M HCl, this catalyst achieved a high Faradaic efficiency of 4.5% with a NH3 yield of 78.4 μg h-1 mgcat.-1 at -0.3 V vs. a reversible hydrogen electrode, thus outperforming most reported NRR electrocatalysts under ambient conditio...
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Ren X, Cui G, Chen L, Xie F, Wei Q, Tian Z, Sun X Tags: Chem Commun (Camb) Source Type: research

DNA logic assembly powered by a triplex-helix molecular switch for extracellular pH imaging.
Abstract We demonstrate a strategy for pH-programmable self-assembly of DNA nanostructures by taking advantage of the pH dependence of reverse Hoogsteen interactions for a triplex-helix molecular switch. This strategy is successfully applied to the construction of molecular logic gates and imaging of extracellular pH. PMID: 30003199 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Qi H, Yue S, Bi S, Ding C, Song W Tags: Chem Commun (Camb) Source Type: research

Exquisite sensitivity of the ligand field to solvation and donor polarisability in coordinatively saturated lanthanide complexes.
Abstract Crystallographic, emission and NMR studies of a series of C3-symmetric, nine-coordinate substituted pyridyl triazacyclononane Yb(iii) and Eu(iii) complexes reveal the impact of local solvation and ligand dipolar polarisability on ligand field strength, leading to dramatic variations in pseudocontact NMR shifts and emission spectral profiles, giving new guidance for responsive NMR and spectral probe design. PMID: 30003200 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Mason K, Harnden AC, Patrick CW, Poh AWJ, Batsanov AS, Suturina EA, Vonci M, McInnes EJL, Chilton NF, Parker D Tags: Chem Commun (Camb) Source Type: research

Three-dimensional layered double hydroxide membranes: fabrication technique, growth mechanism, and enhanced photocatalytic activity.
o S Abstract Novel three-dimensional ZnAl-LDH/AAO and NiAl-LDH/AAO membranes using porous anodic aluminum oxide (AAO) templates as a substrate and an Al3+ source were successfully fabricated via a simple precipitant-free in situ growth technique. These membranes with uniform layered double hydroxide (LDH) plates on the outer and inner surfaces exhibit enhanced activities in photocatalysis. PMID: 30003201 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Xue L, Lü Z, Cheng Y, Sun X, Lin H, Xiao X, Liu X, Zhuo S Tags: Chem Commun (Camb) Source Type: research

Anion-enhanced solvophobic effects in organic solvent.
Abstract The influence of salts on the solvophobic interactions of two non-polar surfaces in organic solvent was examined using a series of molecular balances. Specific anion effects were observed that followed the Hofmeister series and enhanced the solvophobic effect up to two-fold. PMID: 30003202 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Maier JM, Li P, Ritchey JS, Yehl CJ, Shimizu KD Tags: Chem Commun (Camb) Source Type: research

Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure d(-)-tartaric acid.
Abstract Crystal structure determination and mutagenesis analysis of a cis-epoxysuccinate hydrolase which produces enantiomerically pure d(-)-tartaric acids revealed a zinc ion and essential residues in the stereoselective mechanism for the catalytic reaction of the small mirror symmetric substrate. PMID: 30003205 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Dong S, Liu X, Cui GZ, Cui Q, Wang X, Feng Y Tags: Chem Commun (Camb) Source Type: research

CO2-Switchable-hydrophilicity membrane (CO2-SHM) triggered by electric potential: faster switching time along with efficient oil/water separation.
We report a membrane that can be reversibly switched between a hydrophilic state and a hydrophobic state simply by alternately bubbling CO2 into and passing electric potential (EP) through a solution in contact with the membrane. The prepared membrane could be effectively used for oil/water separation. PMID: 30003210 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Rezaee Shirin-Abadi A, Gorji M, Rezaee S, Jessop PG, Cunningham MF Tags: Chem Commun (Camb) Source Type: research

Visible-light circular dichroism of colourless chiral organic compounds enabled by interfacial charge-transfer transitions.
We report the visible-light circular dichroism (CD) of colourless organic compounds based on interfacial charge-transfer (ICT) transitions with TiO2 nanoparticles. We employed three kinds of colourless chiral compounds, l-ascorbic acid, d-ascorbic acid, and l-noradrenaline. These compounds showed a broad ICT band in the visible region between 400 and 600 nm upon their chemisorption on TiO2 nanoparticles. l-Ascorbic acid and l-noradrenaline adsorbed on the TiO2 nanoparticles showed positive and negative CD signals in the visible region, respectively. d-Ascorbic acid, which is the enantiomer of l-ascorbic acid, exhibited pos...
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Fujisawa JI, Kaneko N, Eda T, Hanaya M Tags: Chem Commun (Camb) Source Type: research

Pollen-like ZIF-8 colloidosomes via emulsion templating and etching.
We report a one-pot emulsion-templating strategy for the preparation of ZIF-8 microcapsules both in the presence and absence of surfactants. Capsule diameter is tuneable in the range 1-10 μm, and they can be post-synthetically etched with excess imidazole to form hierarchical architectures resembling Oleaceae pollen grains. PMID: 30003213 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Lupica-Spagnolo L, Ward DJ, Marie JJ, Lymperopoulou S, Bradshaw D Tags: Chem Commun (Camb) Source Type: research

Squaryl group modified phosphoglycolipid analogs as potential modulators of GPR55.
In this study, we developed synthetic access to a novel class of LPGlc analogues featuring a squaryl diamide group as surrogate for the phosphodiester. We report the facile synthesis of a series of LPGlc analogues, their GPR dependent biological activity and a systematic analysis of the structure-activity relationship in regards to GPR55 modulation. The lead compound featuring identical configuration at all stereocenters compared to natural LPGlc exhibits an activity to repel axons of dorsal root ganglion (DGR) nociceptive neurons. PMID: 30003214 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Ding F, Guy AT, Greimel P, Hirabayashi Y, Kamiguchi H, Ito Y Tags: Chem Commun (Camb) Source Type: research

A squaramide-based metal-organic framework as a luminescent sensor for the detection of lactose in aqueous solution and in milk.
Abstract A novel squaramide-containing metal-organic framework (MOF) has been designed and synthesized, which represents the first example of the luminescence selective detection of lactose over other monosaccharides and disaccharides. It was also used for the quantitative determination of lactose in milk. PMID: 30004540 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 13, 2018 Category: Chemistry Authors: Jiang M, Li P, Wu P, Zhang F, Tian X, Deng C, Wang J Tags: Chem Commun (Camb) Source Type: research

Phenylene-bridged cross-conjugated 1,2,3-trisilacyclopentadienes.
Abstract 1,2,3-Trisilacyclopentadienes are obtained from the reactions of cyclotrisilene c-Si3R4 (R = iPr3C6H2) with phenyl and diphenyl acetylene, respectively. With 1,4-diethynyl benzene the cross-conjugated bridging of two of the Si3C2 cycles by a para-phenylene linker is achieved. UV/vis spectroscopy indicates a small but significant effect of cross-conjugation, which is confirmed by TD-DFT calculations. The formation mechanism of the 1,2,3-trisilacyclopentadienes is elucidated by VT NMR. PMID: 29998230 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 12, 2018 Category: Chemistry Authors: Zhao H, Klemmer L, Cowley MJ, Majumdar M, Huch V, Zimmer M, Scheschkewitz D Tags: Chem Commun (Camb) Source Type: research

Recovery of xenon from air over ZIF-8 membranes.
Abstract Continuous ZIF-8 membranes effectively separated air/Xe gas mixtures. These membranes showed air permeances as high as 3.94 × 10-8 mol m-2 s-1 Pa-1 and separation selectivities as high as 12.4 for an air/Xe molar feed composition of 9 : 1. These membranes separated air from Xe via molecular sieving, preferential adsorption, and diffusivity differences. PMID: 29998232 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 12, 2018 Category: Chemistry Authors: Wu T, Lucero J, Sinnwell MA, Thallapally PK, Carreon MA Tags: Chem Commun (Camb) Source Type: research

Copper-catalyzed decarboxylative propargylation/hydroamination reactions: access to C3 β-ketoester-functionalized indoles.
Copper-catalyzed decarboxylative propargylation/hydroamination reactions: access to C3 β-ketoester-functionalized indoles. Chem Commun (Camb). 2018 Jul 12;: Authors: Wang S, Liu M, Chen X, Wang H, Zhai H Abstract A copper-catalyzed reaction of ethynyl benzoxazinanones with readily accessible β-ketoesters via a decarboxylative propargylation/hydroamination sequence has been developed. This protocol furnished a diverse range of C3 β-ketoester-functionalized indoles in good to excellent yields. PMID: 29998241 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 12, 2018 Category: Chemistry Authors: Wang S, Liu M, Chen X, Wang H, Zhai H Tags: Chem Commun (Camb) Source Type: research

A versatile strategy for ultrathin SnS2 nanosheets confined in a N-doped graphene sheet composite for high performance lithium and sodium-ion batteries.
Abstract In this work, few-layer SnS2 nanosheets confined in a nitrogen-doped graphene sheet composite (SnS2/NGS) are successfully synthesized via a facile thermal decomposition method. SnS2/NGS demonstrates sufficient nitrogen-doping and full graphene encapsulation. When evaluated as an anode material for lithium/sodium-ion batteries, it exhibits an excellent electrochemical performance. PMID: 29998261 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 12, 2018 Category: Chemistry Authors: Tao S, Wu D, Chen S, Qian B, Chu W, Song L Tags: Chem Commun (Camb) Source Type: research

Nucleus-targeted DNA tetrahedron as a nanocarrier of metal complexes for enhanced glioma therapy.
Abstract A negatively-charged and nucleus-targeted DNA tetrahedron is rationally designed and used as a nanocarrier of positively-charged metal complexes. This tetrahedron speeds up the translocation of metal complexes into the cell nucleus, and inhibits the growth and invasion of glioma cells by triggering vascular mimicry-associated signaling pathways, thus achieving precise glioma treatment. PMID: 29998263 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 12, 2018 Category: Chemistry Authors: Tian Y, Huang Y, Gao P, Chen T Tags: Chem Commun (Camb) Source Type: research

TiO(OH)2 can exceed the critical limit of conventional CO2 sorbents: modification needed for high capacity and selectivity.
Abstract High-performance CO2 sorbents typically contain both alkaline compounds and inert supporting materials. The convention is broken by TiO(OH)2. The CO2 sorption capacity of nanostructured TiO(OH)2 reaches 6.1 mmol g-1, while its CO2 sorption selectivity for CO2/N2 mixtures is much higher than that of state-of-the-art sorbents, activated carbon and zeolite, which is another surprise. PMID: 29998264 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - July 12, 2018 Category: Chemistry Authors: Wu F, Dellenback PA, Toan S, Russell CK, Fan M Tags: Chem Commun (Camb) Source Type: research