A multi-responsive cross-linked supramolecular polymer network constructed by mussel yield coordination interaction and pillar[5]arene-based host-guest complexation.
Abstract Here a novel cross-linked supramolecular polymer network with thermal, pH, and H2S responsiveness was prepared inspired by mussel yield catechol-Fe3+ coordination and pillar[5]arene-based host-guest interactions. PMID: 30310888 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Liu Y, Shangguan L, Shi B Tags: Chem Commun (Camb) Source Type: research

Si nanoflake-assembled blocks towards high initial coulombic efficiency anodes for lithium-ion batteries.
Abstract Assisted by artificial amorphous copper silicate, Si with a flake-like structure was obtained through a facile magnesiothermic reduction. The Si anodes exhibit excellent cyclic performance and rate performance. Particularly, a high initial coulombic efficiency of 85%-89% was obtained due to their greatly reduced surface and internal defects. PMID: 30310889 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Zhou X, Ren Y, Yang J, Ding J, Zhang J, Hu T, Tang J Tags: Chem Commun (Camb) Source Type: research

Quantitative analysis of cell-free synthesized membrane proteins at the stabilized droplet interface bilayer.
We report the functional synthesis and quantification of membrane proteins-α-hemolysin from Staphylococcus aureus and the multidrug transporter EmrE from Escherichia coli-at the stabilized droplet interface bilayer using an in vitro transcription-translation system. The system developed here can expand the list of integral membrane proteins applicable for quantitative functional analysis. PMID: 30310891 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Elfaramawy MA, Fujii S, Uyeda A, Osaki T, Takeuchi S, Kato Y, Watanabe H, Matsuura T Tags: Chem Commun (Camb) Source Type: research

A catalytic one-step synthesis of peptide thioacids: the synthesis of leuprorelin via iterative peptide-fragment coupling reactions.
Abstract A catalytic one-step synthesis of peptide thioacids was developed. The oxygen-sulfur atom exchange reaction converted the carboxy group at the C-terminus of the peptides into a thiocarboxy group with suppressed epimerization. This method was successfully applied to the synthesis of the peptide drug leuprorelin via an iterative fragment-coupling protocol. PMID: 30310900 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Matsumoto T, Sasamoto K, Hirano R, Oisaki K, Kanai M Tags: Chem Commun (Camb) Source Type: research

Bimetallic metal organic frameworks with precisely positioned metal centers for efficient H2 storage.
Abstract We demonstrated that the ratio and position of two different metal ions, Pd and Cu, can be precisely controlled within MOFs through predesigned metal clusters. These MOF structures incorporating Pd-Cu paddle wheel units were synthesised simply by reacting Pd-Cu acetate metal clusters and tritopic organic linkers at room temperature. Pd-Cu open metal sites were found to be uniformly distributed throughout the MOFs with a ca. 1 : 1 ratio. The incorporation of Pd into the MOF structure also led to enhanced affinity towards H2 with Qst values up to 8.9 kJ mol-1. PMID: 30310902 [PubMed - as ...
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Kim D, Song KS, Buyukcakir O, Yildirim T, Coskun A Tags: Chem Commun (Camb) Source Type: research

Regiocontrol in the cobalt-catalyzed hydrosilylation of alkynes.
Abstract Hydrofunctionalizations of unsaturated hydrocarbons are key strategies for the synthesis of functionalized building blocks. Here, we report highly versatile cobalt-catalyzed hydrosilylations of alkynes that operate with minute amounts of the inexpensive, bench-stable pre-catalyst Co(OAc)2·4H2O under mild conditions (0.1-1 mol%, THF, r.t., 1 h). Near-perfect regiocontrol/stereocontrol was induced by the choice of the ligand: bidentate phosphines afforded (E)-β-vinylsilanes; α-vinylsilanes formed with bipyridine ligands. PMID: 30310911 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Wu G, Chakraborty U, Jacobi von Wangelin A Tags: Chem Commun (Camb) Source Type: research

Development of efficient palladium catalysts for alkoxycarbonylation of alkenes.
Abstract Herein, we report a general and efficient Pd-catalysed alkoxycarbonylation of sterically hindered and demanding olefins including a variety of tri-, tetra-substituted and 1,1-disubstituted alkenes. In the presence of 1,3-bis(tert-butyl(pyridin-2-yl)phosphanyl)propane L3 or 1,4-bis(tert-butyl(pyridin-2-yl)phosphanyl)butane L4 the desired esters are obtained in good yields and selectivities. Similar transformation is obtained using tertiary ether as showcased in the carbonylation of MTBE to the corresponding linear ester in high yield and selectivity. PMID: 30311607 [PubMed - as supplied by publisher] ...
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Liu J, Dong K, Franke R, Neumann H, Jackstell R, Beller M Tags: Chem Commun (Camb) Source Type: research

CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins.
Abstract In the context of discovering and quantifying terminal alkyne-based natural products, here we report the combination of CuAAC click chemistry with LC-MS for the detection of polyether toxins (prymnesins) associated with harmful algal blooms. The added-value of the CuAAC-based approach is evident from our ability to detect novel prymnesin-like compounds in algal species with previously uncharacterised toxins. PMID: 30311608 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Hems ES, Wagstaff BA, Saalbach G, Field RA Tags: Chem Commun (Camb) Source Type: research

Catalytic hydrogenation of carboxylic acids using low-valent and high-valent metal complexes.
Abstract Carboxylic acids are ubiquitous in bio-renewable and petrochemical sources of carbon. The hydrogenation of carboxylic acids to alcohols generates water as the only by-product, and thus represents a sustainable method for the production of these alternative energy carriers/platform chemicals on a large scale. Herein, we offer a brief account of the development of this new concept and molecular insights into cationic mononuclear low- and high-valent transition-metal complexes for the hydrogenation of carboxylic acids. PMID: 30311923 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Yoshioka S, Saito S Tags: Chem Commun (Camb) Source Type: research

Hyperpolarized fumarate via parahydrogen.
nnemann K Abstract We produce hyperpolarized [1-13C]fumarate in the proton nuclear spin singlet state by pairwise trans-addition of parahydrogen to a molecular precursor using a ruthenium-based catalyst in water. The proton singlet state is transformed into observable carbon magnetization by radiofrequency pulses to enhance the 13C signal by a factor of 1000 using 50% para-enriched hydrogen gas. PMID: 30311932 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Ripka B, Eills J, Kouřilová H, Leutzsch M, Levitt MH, Münnemann K Tags: Chem Commun (Camb) Source Type: research

Strategic use of CuAlO2 as a sustained release catalyst for production of hydrogen from methanol steam reforming.
Abstract Using the new method of sustained release catalysis, CuAlO2 demonstrates stable catalytic performance for methanol steam reforming (MSR). Importantly, the used catalyst can be completely restored to its original state by a simple calcination treatment, demonstrating the super regenerability of the catalytic system. PMID: 30311934 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Qing S, Hou X, Liu Y, Li L, Wang X, Gao Z, Fan W Tags: Chem Commun (Camb) Source Type: research

The electronic structure of f-element Prussian blue analogs determined by soft X-ray absorption spectroscopy.
In this study, isostructural trivalent lanthanide and tetravalent actinide Prussian blue analogs' valence orbitals are probed by soft X-ray absorption measurements. PMID: 30306148 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Dumas T, Guillaumont D, Moisy P, Shuh DK, Tyliszczak T, Solari PL, Den Auwer C Tags: Chem Commun (Camb) Source Type: research

A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress.
Abstract A novel ratiometric fluorescent probe with high selectivity and sensitivity was designed and developed for bioimaging and biosensing of HBrO in mitochondria. Using this useful tool with low cytotoxicity and good biocompatibility, it was found that O2˙--induced oxidative stress triggered the burst of HBrO in mitochondria. PMID: 30306159 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Huang H, Tian Y Tags: Chem Commun (Camb) Source Type: research

Light-induced cargo release from a cucurbit[8]uril host by means of a sequential logic operation.
hel U Abstract The logically controlled and light-induced release of a tripeptide model cargo from a cucurbit[8]uril host macrocycle by means of a photoswitch was shown in water. This provides a new approach to photoresponsive and selective release in a meaningful pH window. PMID: 30306161 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Romero MA, Fernandes RJ, Moro AJ, Basílio N, Pischel U Tags: Chem Commun (Camb) Source Type: research

Amorphous Y(OH)3-promoted Ru/Y(OH)3 nanohybrids with high durability for electrocatalytic hydrogen evolution in alkaline media.
Abstract A novel Ru/Y(OH)3 nanohybrid with high activity and excellent durability for electrocatalytic hydrogen evolution in alkaline media was developed. The enhanced performance mainly arose from the amorphous Y(OH)3 scaffold that both facilitates water dissociation and enhances the structural stability of Ru/Y(OH)3 due to the strong interaction between Ru and Y(OH)3. PMID: 30306183 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Liu Y, Lu X, Che Z, Zhang C, Han M, Bao J, Dai Z Tags: Chem Commun (Camb) Source Type: research

Exploring the potential and design of zeolite nanosheets as pervaporation membranes for ethanol extraction.
Abstract Molecular dynamics simulations are employed to demonstrate the potential of zeolite nanosheets as pervaporation membranes for ethanol extraction. Our results show that zeolite nanosheets can provide orders of magnitude higher fluxes compared to currently available membranes and achieve outstanding separation factors. The dominant role of membrane surfaces in determining the separation performance is also identified and explored at an atomic level. Developing nanosheet membranes with hydrophobic surfaces and/or with a minimal surface silanol density represents the keys to enable highly selective separation...
Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Zou C, Lin LC Tags: Chem Commun (Camb) Source Type: research

From 1D ordered linear polymers to discrete macrocycles: surface adsorption and pH take control.
Abstract In this work we demonstrate that the surface adsorption and pH play a determining role in controlling the final product of a Schiff base reaction. Either 1D linear polymers or discrete macrocycles can be obtained by tuning the pH and surface confinement. PMID: 30307459 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Cao L, Yu Y, Lei S Tags: Chem Commun (Camb) Source Type: research

One pot ligand exchange method for a highly stable Au-SBA-15 catalyst and its room temperature CO oxidation.
Abstract A modified deposition precipitation (DP) method has been developed to address a fundamental issue of supporting well dispersed Au nanoparticles on silica. Ammonium chloride (NH4Cl) plays an important role in in situ modifying the gold precursor (HAuCl4·3H2O) solution allowing facile deposition of gold NPs in the channels of SBA-15. The Au-SBA-15 catalyst (2.8 wt%) synthesized by this procedure showed 100% conversion for CO oxidation at room temperature with excellent stability at room temperature and high temperature. PMID: 30307460 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 11, 2018 Category: Chemistry Authors: Soni Y, Kavya I, Ajithkumar TG, Vinod CP Tags: Chem Commun (Camb) Source Type: research

Dimensional tailoring of hydrothermally grown zinc oxide nanostructures in a continuous flow micro reactor.
Abstract Dynamic deposition of ZnO nanostructures with varying morphologies (nanorods, nanocones, nanopencils, nanosheets, etc.), diameters, lengths and aerial densities on ITO-PET substrates has been achieved using a continuous flow microreactor in which we maintained a homeostatic zinc concentration and varied the other reactants' concentrations. PMID: 30302446 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Parashar VK, Gijs M Tags: Chem Commun (Camb) Source Type: research

An efficient multifunctional hybrid electrocatalyst: Ni2P nanoparticles on MOF-derived Co,N-doped porous carbon polyhedrons for oxygen reduction and water splitting.
Abstract Ni2P nanoparticles anchored on MOF-derived Co,N-doped porous carbon polyhedrons (Ni2P/CoN-PCP) were successfully prepared. The Ni2P/CoN-PCP catalyst shows excellent trifunctional electrocatalytic performances for the oxygen reduction, oxygen evolution, and hydrogen evolution reactions, attributed to the synergistic effect between active Ni2P nanoparticles and the CoN-PCP support with rich Co-Nx centres, abundant defects and high conductivity. This work demonstrates a superior low-cost electrocatalyst for potential application in fuel cells and water splitting devices. PMID: 30302447 [PubMed - as supp...
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Sun T, Zhang S, Xu L, Wang D, Li Y Tags: Chem Commun (Camb) Source Type: research

Consecutive one-/two-step relaxation transformations of single-molecule magnets via coupling dinuclear dysprosium compounds with chloride bridges.
Abstract The double chloride-bridged dimer of a dinuclear dysprosium(iii) single-molecule magnet (SMM) was successfully isolated by assembling centrosymmetric dinuclear Dy2 SMMs. Such structural transformation involves the generation and cleavage of chloride bridges and leads to consecutive transformations of one- and two-step slow relaxation of magnetization. PMID: 30302448 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Tian H, Wang BL, Lu J, Liu HT, Su J, Li D, Dou J Tags: Chem Commun (Camb) Source Type: research

From double-shelled grids to supramolecular frameworks.
Abstract Structurally unique double-shelled 4f and 3d-4f supramolecular grids were constructed and assembled into 3D hydrogen-bonded organic frameworks (HOFs), with the 3d-4f heterometallic HOF showing single-molecule magnet (SMM) behaviour. PMID: 30302449 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Wu J, Guo M, Li XL, Zhao L, Sun QF, Layfield RA, Tang J Tags: Chem Commun (Camb) Source Type: research

Rh(iii)-Catalyzed ortho-C-(sp2)-H amidation of ketones and aldehydes under synergistic ligand-accelerated catalysis.
Abstract Rh(iii)-Catalyzed ortho-C-H amidation of ketones and aldehydes under cooperative metal organocatalysis has been utilized for synthesizing various ortho-amidocarbonyl analogs, and the reaction for the aldehyde proceeds at ambient temperature. The aniline derivative 3,5-bis(trifluoromethyl)aniline promotes the amidation reaction via a transient imine directing group. The efficient amidation agent is dioxazolone. The synthetic utility has been demonstrated in the synthesis of quindolinone alkaloids. PMID: 30302452 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Hande AE, Ramesh VB, Prabhu KR Tags: Chem Commun (Camb) Source Type: research

Molecular electronic spin qubits from a spin-frustrated trinuclear copper complex.
s W Abstract The trinuclear copper(ii) complex [Cu3(saltag)(py)6]ClO4 (H5saltag = tris(2-hydroxybenzylidene)triaminoguanidine) was synthesized and characterized by experimental as well as theoretical methods. This complex exhibits a strong antiferromagnetic coupling (J = -298 cm-1) between the copper(ii) ions, mediated by the N-N diazine bridges of the tritopic ligand, leading to a spin-frustrated system. This compound shows a T2 coherence time of 340 ns in frozen pyridine solution, which extends to 591 ns by changing the solvent to pyridine-d5. Hence, the presented compound is a promising candidate as a building ...
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Kintzel B, Böhme M, Liu J, Burkhardt A, Mrozek J, Buchholz A, Ardavan A, Plass W Tags: Chem Commun (Camb) Source Type: research

Organosoluble tetravalent actinide di- and trifluorides.
Abstract Soluble molecular actinide(iv) fluorides can be prepared in high yield via redox or metathesis reactions of silver fluorides with actinide compounds containing ancillary iodide or fluorinated thiolate ligands. Two compounds, (py)4UF2I2·2py and (py)7Th2F5(SC6F5)3·2py were isolated and characterized by conventional methods, powder and low temperature single crystal X-ray diffraction. PMID: 30302458 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Gotthelf G, Stuber MA, Kornienko AY, Emge TJ, Brennan JG Tags: Chem Commun (Camb) Source Type: research

A new strategy for constructing a disulfide-functionalized ZIF-8 analogue using structure-directing ligand-ligand covalent interaction.
Abstract Inter-ligand van der Waals forces play a key role in the synthesis of different ZIF types. Here we report an unusual case involving covalent inter-ligand interactions through disulfide bond formation in a ZIF-8 analogue. It exhibits high CO2 uptake and stepwise adsorption of light hydrocarbons with potential applications in ethane/ethylene separation. PMID: 30302467 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Gai Y, Chen X, Yang H, Wang Y, Bu X, Feng P Tags: Chem Commun (Camb) Source Type: research

Assisted π-stacking: a strong synergy between weak interactions.
We report assisted π-stacking, a synergy between aromatic π-stacking and n → π* interactions that exhibits an unprecedented strength and thermal stability. Natural bond orbital analysis reveals the non-additive nature of the interaction. PMID: 30302470 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Sao S, Naskar S, Mukhopadhyay N, Das M, Chaudhuri D Tags: Chem Commun (Camb) Source Type: research

Properties and prospects for rhenium(i) tricarbonyl N-heterocyclic carbene complexes.
Abstract Re(i) complexes bound to π-conjugated bidentate N-heterocyclic carbene ligands with formulation Re(CO)3(N^NHC)L (where N^NHC represents an imidazole or benzimidazole carbene ligand conjugated to a N-based heterocycle such as pyridine, pyrimidine, quinoline or quinoxaline) are a relatively new class of complexes belonging to the archetypal family of well known luminescent Re(CO)3(diim)X species (where diim is a conjugated diimine ligand and X is a halogen anion). The complexes Re(CO)3(N^NHC)L are characterised by blue-shifted emission compared to Re(CO)3(diim)X, but with shorter excited state lifetime d...
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Simpson PV, Falasca M, Massi M Tags: Chem Commun (Camb) Source Type: research

π-Conjugated thiolate amplified spectrophotometry nitrite assay with improved sensitivity and accuracy.
π-Conjugated thiolate amplified spectrophotometry nitrite assay with improved sensitivity and accuracy. Chem Commun (Camb). 2018 Oct 10;: Authors: Zhang L, Wu X, Yuan Z, Lu C Abstract We proposed a π-conjugation enhanced molar absorption coefficient strategy that can effectively improve the sensitivity of the spectrophotometry sensing technique. As a case study, the strategy was demonstrated for sensitive nitrite detection based on the typical nitrite-thiol reaction. PMID: 30302484 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Zhang L, Wu X, Yuan Z, Lu C Tags: Chem Commun (Camb) Source Type: research

Divergent synthesis of N-heterocycles by Pd-catalyzed controllable cyclization of vinylethylene carbonates.
Abstract Here, we report a palladium-catalyzed controllable cyclization of vinyl ethylene carbonates that proceeds through formal migration [2+3] and [5+2] cycloadditions, respectively, under mild conditions. The transformation described here affords a series of synthetically versatile 5,7-membered N-heterocycles which are found in natural products and pharmaceuticals with biological and medicinal properties. PMID: 30302489 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Yang Y, Yang W Tags: Chem Commun (Camb) Source Type: research

Selective aerobic oxidation of alkyl aromatics on Bi2MoO6 nanoplates decorated with Pt nanoparticles under visible light irradiation.
This study opens a new window for direct C-H functionalization through the photocatalytic method based on cheap Bi2MoO6 semiconductor materials. PMID: 30303206 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Zhang B, Yang X, Li J, Cheng G Tags: Chem Commun (Camb) Source Type: research

Design of dispersant structures for preparing highly concentrated one-dimensional inorganic molecular chains from V2Se9 crystals.
Abstract We studied dispersants for exfoliating bulk V2Se9 into one dimensional chain units. V2Se9, with a negative zeta potential of -30.1 mV, was acidic and strongly anchored with the amine head of octadecylamine by charge transfer reaction. The steric hindrance by the octadecyl tail promoted the dispersion of V2Se9 to the nano level. PMID: 30303207 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 10, 2018 Category: Chemistry Authors: Chae S, Siddiqa AJ, Kim BJ, Oh S, Choi KH, Kim HY, Lee KH, Yu HK, Choi JY Tags: Chem Commun (Camb) Source Type: research

Synthesis and thermo-responsive behavior of helical polyacetylenes derived from proline.
Abstract A series of optically active helical poly[(S)-2-ethynyl-N-aliphatic acylpyrrolidine] were efficiently synthesized from a commercially available biomass-based starting material, and that bearing a short propionyl substituent exhibited an unexpected lower critical solution temperature in an aqueous solution with a narrow phase-transition window and a small hysteresis. PMID: 30298143 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Shi G, Wang S, Guan X, Zhang J, Wan X Tags: Chem Commun (Camb) Source Type: research

Correction: Fe-Catalyzed three-component carboazidation of alkenes with alkanes and trimethylsilyl azide.
Abstract Correction for 'Fe-Catalyzed three-component carboazidation of alkenes with alkanes and trimethylsilyl azide' by Wei-Yu Li et al., Chem. Commun., 2018, DOI: 10.1039/c8cc05090b. PMID: 30298148 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Li WY, Wu CS, Wang Z, Yang L Tags: Chem Commun (Camb) Source Type: research

LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Abstract The chemical compound LY2874455 has the potential to overcome drug resistance driven by FGFR gatekeeper mutations. X-ray crystallographic studies provide the structural explanation for why this compound is effective against the FGFR gatekeeper mutations. PMID: 30298149 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Wu D, Guo M, Min X, Dai S, Li M, Tan S, Li G, Chen X, Ma Y, Li J, Jiang L, Qu L, Zhou Z, Chen Z, Chen L, Xu G, Chen Y Tags: Chem Commun (Camb) Source Type: research

Cyclic Pt3Ag33 and Pt3Au12Ag21 nanoclusters with M13 icosahedra as building-blocks.
Abstract In this work, we report a controlled self-assembly of three M13 icosahedral building-blocks into cyclic Pt3Ag33 or Pt3Au12Ag21 nanoclusters. Compared to the previously reported Pt2Ag23 and Pt1Ag12 nanoclusters, the Pt3Ag33 nanoclusters exhibit a red-shift in both the optical absorption and photoluminescence due to the assembly of an additional Pt1Ag12 icosahedron. PMID: 30298154 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Yang S, Chai J, Lv Y, Chen T, Wang S, Yu H, Zhu M Tags: Chem Commun (Camb) Source Type: research

Porous coordination/covalent hybridized polymers synthesized from pyridine-zinc coordination compound and their CO2 capture ability, fluorescence and selective response properties.
In this study, we propose the synthesis of a porous coordination/covalent hybridized polymer from di(4-vinylpyridine)-dichloro-zinc (ZnVP2) by "coordination-polymerization" method. The resulting porous polymer demonstrated CO2 capture ability and multi-responsive properties. PMID: 30298158 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Zhang Q, Xiong Y, Liu J, Zhang T, Liu L, Huang Y Tags: Chem Commun (Camb) Source Type: research

Expeditious synthesis of multisubstituted indoles via multiple hydrogen transfers.
Abstract Described herein is the expeditious construction of multi-substituted indole skeletons via multiple hydrogen transfers. When ortho-amino ketoesters were treated with a catalytic amount of TiCl4 in the presence of 1.0 equivalent of dehydrating reagent, three types of hydrogen transfer processes ([1,5]-hydride shift, proton transfer, and [1,2]-hydride shift) occurred to give various 3-alkoxycarbonylindoles. Further study revealed that a [1,2]-alkyl shift instead of a [1,2]-hydride shift proceeded to afford 3-alkylindoles from the substrates with an amino group having tertiary carbons adjacent to a nitrogen ...
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Yoshida T, Mori K Tags: Chem Commun (Camb) Source Type: research

Continuous flow biodiesel production from wet microalgae using a hybrid thin film microfluidic platform.
Abstract A novel continuous flow turbo-thin film device (T2FD) has been developed. The microfluidic platform is effective in high yielding production of biodiesel from wet microalgae at room temperature under continuous flow conditions. These findings open the possibility of cost effective production of biodiesel directly from wet microalgae. PMID: 30298163 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Sitepu EK, Jones DB, Tang Y, Leterme SC, Heimann K, Zhang W, Raston CL Tags: Chem Commun (Camb) Source Type: research

Mesoporous S doped Fe-N-C materials as highly active oxygen reduction reaction catalyst.
Abstract Mesoporous Fe, S, N doped carbon (m-FeSNC) materials have been successfully synthesized by pyrolysis of polymerized o-phenylenediamine using binary initiators. It exhibited high electrocatalytic activity towards oxygen reduction reaction, and zinc-air battery with higher performance has been fabricated using m-FeSNC than using commercial Pt/C. PMID: 30298164 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Guan Z, Zhang X, Chen W, Pei J, Liu D, Xue Y, Zhu W, Zhuang Z Tags: Chem Commun (Camb) Source Type: research

The growth and fluorescence of phthalocyanine monolayers, thin films and multilayers on hexagonal boron nitride.
Abstract Free-base phthalocyanine forms distinct interfacial phases and thin films on hexagonal boron nitride including a monolayer arrangement as determined using high resolution atomic force microscopy. The phases reveal significant differences in photoluminescence with an intense peak for monolayer coverages of flat-lying molecules which is red-shifted in agreement with theoretical models. PMID: 30298868 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Alkhamisi M, Korolkov VV, Nizovtsev AS, Kerfoot J, Taniguchi T, Watanabe K, Besley NA, Besley E, Beton PH Tags: Chem Commun (Camb) Source Type: research

Intramolecular interaction suggests an autosuppression mechanism for the innate immune adaptor protein MyD88.
Abstract MyD88 (myeloid differentiation factor 88) is an important protein in innate immunity. Two structural domains of MyD88 have been well characterized separately, but the global architecture of full-length MyD88 remained unclear. Here, we propose an autosuppressive mechanism of MyD88 regulated by the intramolecular interaction between the two domains. PMID: 30298869 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Uno M, Watanabe-Nakayama T, Konno H, Akagi KI, Tsutsumi N, Fukao T, Shirakawa M, Ohnishi H, Tochio H Tags: Chem Commun (Camb) Source Type: research

A lotus-inspired janus hybrid film enabled by interfacial self-assembly and in situ asymmetric modification.
Abstract A lotus leaf inspired Janus hybrid film was exquisitely fabricated through a self-assembly process at the air/water interface with subsequent in situ asymmetric modification at the oil/water interface. The interfacial asymmetric decoration strategy thus provides a novel pathway for achieving a 2D Janus hybrid film with asymmetric wettability and functionality. PMID: 30298870 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Liang Y, Shi J, Xiao P, He J, Ni F, Zhang J, Huang Y, Huang CF, Chen T Tags: Chem Commun (Camb) Source Type: research

Rational design of a lipid-droplet-polarity based fluorescent probe for potential cancer diagnosis.
Abstract A robust fluorescent probe CTPA has been rationally designed for cancer diagnosis by monitoring lipid drop (LD) polarity and number variation. With the outstanding properties of CTPA, we have shown that the diagnosis of cancer can be achieved not only at the cellular levels but also in organs and living mice for the first time. PMID: 30298871 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Yin J, Peng M, Ma Y, Guo R, Lin W Tags: Chem Commun (Camb) Source Type: research

Conformationally flexible arylethynyl bis-urea receptors bind disparate oxoanions with similar, high affinities.
Abstract Conformationally flexible hosts with relatively small binding pockets are seldom shown to bind oxoanions preferentially over other guests. Herein, we disclose the binding of diprotic, monoprotic, and aprotic tetrahedral oxoanions with three different pyridylethynyl bis-urea scaffolds. In less polar solvent, the trend in association constants appears to be heavily influenced by solvation and entropic effects. However, in a more polar solvent, the trend in association constants matches that of the pKa of the conjugate acid of the anionic guest, as expected for H-bond donating hosts. PMID: 30298881 [Pub...
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Eytel LM, Brueckner AC, Lohrman JA, Haley MM, Cheong PH, Johnson DW Tags: Chem Commun (Camb) Source Type: research

Essential but sparse collagen hydroxylysyl post-translational modifications detected by DNP NMR.
Abstract The sparse but functionally essential post-translational collagen modification 5-hydroxylysine can undergo further transformations, including crosslinking, O-glycosylation, and glycation. Dynamic nuclear polarization (DNP) and stable isotope enriched lysine incorporation provide sufficient solid-state NMR sensitivity to identify these adducts directly in skin and vascular smooth muscle cell extracellular matrix (ECM), without extraction procedures, by comparison with chemical shifts of model compounds. Thus, DNP provides access to the elucidation of structural consequences of collagen modifications in int...
Source: Chemical Communications - October 9, 2018 Category: Chemistry Authors: Chow WY, Li R, Goldberga I, Reid DG, Rajan R, Clark J, Oschkinat H, Duer MJ, Hayward R, Shanahan CM Tags: Chem Commun (Camb) Source Type: research

Selective monoalkylation of p-tert-butylcalix-[4]-arene in a methyl carbonate ionic liquid.
Abstract Methyl carbonate ionic liquids are shown to readily mono-deprotonate p-tert-butylcalix-[4]-arenes initiating the formation of an organic mono-anionic p-tert-butylcalix-[4]-arate salt, methanol and carbon dioxide. These calix-[4]-arate salts have been successfully used in alkylation reactions with dialkyl sulfates and alkyl halides to form a mono-alkylated single product with high yield. This method avoids the common use of alkali metal bases such as caesium fluoride hence providing a safer and more selective synthetic route. PMID: 30294733 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 8, 2018 Category: Chemistry Authors: Whiteside RE, Gunaratne HQN, Muzio AFV, Nockemann P Tags: Chem Commun (Camb) Source Type: research

A four-state fluorescent molecular switch.
Abstract Four distinct fluorescent states are achieved in a single Weak-Link Approach (WLA) construct bearing pyrene and tetraphenylethene moieties. The fluorescence of the compound in both the solution and solid phases can be manipulated through reversible coordination chemistry at the PtII center. PMID: 30294737 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 8, 2018 Category: Chemistry Authors: Liu Y, Zhou J, Wasielewski MR, Xing H, Mirkin CA Tags: Chem Commun (Camb) Source Type: research

Intermolecular π-hole/n→π* interactions with carbon monoxide ligands in crystal structures.
Intermolecular π-hole/n→π* interactions with carbon monoxide ligands in crystal structures. Chem Commun (Camb). 2018 Oct 08;: Authors: Doppert MT, van Overeem H, Mooibroek TJ Abstract A thorough analysis of the Cambridge Structure Database reveals that intermolecular π-hole/n→π* interactions with carbon monoxide ligands are abundant in the solid state and somewhat directional, particularly with fac-like M(CO)3 fragments (P
Source: Chemical Communications - October 8, 2018 Category: Chemistry Authors: Doppert MT, van Overeem H, Mooibroek TJ Tags: Chem Commun (Camb) Source Type: research

Square-planar Co(iii) in {O4} coordination: large ZFS and reactivity with ROS.
Abstract Oxidation of distorted square-planar perfluoropinacolate Co compound [CoII(pinF)2]2-, 1, to [CoIII(pinF)2]1-, 2, is reported. Rigidly square-planar 2 has an intermediate-spin, S = 1, ground state and very large zero-field splitting (ZFS) with D = 67.2 cm-1; |E| = 18.0 cm-1, (E/D = 0.27), g⊥ = 2.10, g‖ = 2.25 and χTIP = 1950 × 10-6 cm3 mol-1. This Co(iii) species, 2, reacts with ROS to oxidise two (pinF)2- ligands to form tetrahedral [CoII(Hpfa)4]2-, 3. PMID: 30294742 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - October 8, 2018 Category: Chemistry Authors: Steele JL, Tahsini L, Sun C, Elinburg JK, Kotyk CM, McNeely J, Stoian SA, Dragulescu-Andrasi A, Ozarowski A, Ozerov M, Krzystek J, Telser J, Bacon JW, Golen JA, Rheingold AL, Doerrer LH Tags: Chem Commun (Camb) Source Type: research