Acquired Strabismus in Linear Scleroderma of the Face.
PMID: 31197382 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - June 14, 2019 Category: Dermatology Authors: Martini G, Zannin ME, Rodeghiero F, Dal Pos S, Zulian F Tags: Acta Derm Venereol Source Type: research

Hyperpigmented Plaque on a Farmer's Nose: A Quiz.
PMID: 31197383 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - June 14, 2019 Category: Dermatology Authors: Liu W, Ma JY, Ma DL Tags: Acta Derm Venereol Source Type: research

Extreme Incidence of Skin Cancer in Kidney and Liver Transplant Recipients Living with High Sun Exposure.
PMID: 31197384 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - June 14, 2019 Category: Dermatology Authors: Plasmeijer EI, Jiyad Z, Way M, Marquart L, Miura K, Campbell S, Isbel N, Fawcett J, Ferguson LE, Davis M, Whiteman DC, Soyer HP, O'Rourke P, Green AC Tags: Acta Derm Venereol Source Type: research

Linear Hyperkeratotic Papules on Extremities Together with Oral Ulcers: A Quiz.
nther C PMID: 31197385 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - June 14, 2019 Category: Dermatology Authors: Heyne S, Hägele B, Beissert S, Günther C Tags: Acta Derm Venereol Source Type: research

Actinic Cheilitis: Analysis of Clinical Subtypes, Risk Factors and Associated Signs of Actinic Damage.
S, Suárez Conde I, Pereiro-Ferreirós M PMID: 31197386 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - June 14, 2019 Category: Dermatology Authors: Rodríguez-Blanco I, Flórez Á, Paredes-Suárez C, Rodríguez-Lojo R, González-Vilas D, Ramírez-Santos A, Paradela S, Suárez Conde I, Pereiro-Ferreirós M Tags: Acta Derm Venereol Source Type: research

Association Between Atopic Dermatitis and Cardiovascular Disease: A Nationwide Register-based Case-control Study from Sweden.
In conclusion, in this study, AD was associated with CVD, and this should be kept in mind, especially when managing patients with severe AD. PMID: 31197387 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - June 14, 2019 Category: Dermatology Authors: Ivert LU, Johansson EK, Dal H, Lindelöf B, Wahlgren CF, Bradley M Tags: Acta Derm Venereol Source Type: research

Ulceronecrotic Lesions in a Man with Familial Mediterranean Fever: A Quiz.
PMID: 31141153 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 29, 2019 Category: Dermatology Authors: Toberer F, Hartmann M Tags: Acta Derm Venereol Source Type: research

Four-week Urticaria Activity Score 7 as a Useful Patient-reported Outcome to Assess Chronic Spontaneous Urticaria: A Multicentre Study Evaluation of Adherence and Patients' Perspective.
PMID: 31141154 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 29, 2019 Category: Dermatology Authors: Patruno C, Napolitano M, Ferrucci S, Brambilla L, Hansel K, Corazza M, Schena D, Foti C, Romita P, Gallo R, Stingeni L Tags: Acta Derm Venereol Source Type: research

Non-random Plaque-site Recurrence of Psoriasis in Patients Treated with Dead Sea Climatotherapy.
PMID: 31141155 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 29, 2019 Category: Dermatology Authors: Emmanuel T, Lybaek D, Johansen C, Iversen L Tags: Acta Derm Venereol Source Type: research

Signal Transducer and Activator of Transcription 3 in Keratinocytes Regulates Histaminergic Itch but Not Nonhistaminergic Itch.
PMID: 31141156 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 29, 2019 Category: Dermatology Authors: Hashimoto T, Sakai K, Yosipovitch G, Akiyama T Tags: Acta Derm Venereol Source Type: research

Skin and Soft Tissue Infections Caused by Mycobacterium chelonae: More Common Than Expected?
We report here 5 patients with cutaneous and/or soft tissue infection due to M. chelonae who were diagnosed and treated at our centre. Two of the 5 patients were on immunosuppressive treatment. While clinical presentations differed in each patient, all had a long history of skin lesions. In addition to careful history-taking, tissue biopsies were obtained for mycobacterial culture and histopathological examination. Culture-directed antibiotic therapy was initiated, which resulted in a slow, but continuous, healing of the lesions. In summary, M. chelonae infections are still relatively rare, but should be considered in both...
Source: Acta Dermato-Venereologica - May 29, 2019 Category: Dermatology Authors: Uslu U, Böhm O, Heppt F, Sticherling M Tags: Acta Derm Venereol Source Type: research

Blau Syndrome: Report of a Rare Entity with Congenital Ostium Secundum Atrial Septal Defect in a 7-year-old Chinese Girl.
PMID: 31120540 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 23, 2019 Category: Dermatology Authors: Yang XH, Lin L, Sun JF, Jiang YQ Tags: Acta Derm Venereol Source Type: research

Clinical Efficacy of Oligofructans from Ophiopogon japonicus in Reducing Atopic Dermatitis Flare-ups in Caucasian Patients.
Abstract Atopic dermatitis is a chronic relapsing inflammatory skin disease affecting 15-20% children and 2-10% adults worldwide. Topical treatments include corticosteroids and calcineurin inhibitors, despite frequently observed adverse events such as skin atrophy, itching and burning sensations. Good alternatives that can prolong disease relief in between flare-ups are therefore needed. We conducted a randomized, single-blind, placebo-controlled, multicenter clinical trial in a Caucasian cohort of 104 children and 144 adults with mild-to-moderate atopic dermatitis that applied tested products twice daily for 60 d...
Source: Acta Dermato-Venereologica - May 23, 2019 Category: Dermatology Authors: Mainzer C, le Guillou M, Vyumvuhore R, Chadoutaud B, Bordes S, Closs B Tags: Acta Derm Venereol Source Type: research

A Review of Cutaneous Microdialysis of Inflammatory Dermatoses.
Abstract Microdialysis is a minimally invasive technique to study metabolic, biochemical, and pharmacological events in tissue. Factors that influence microdialyslate collection include molecular weight cutoff of the membrane, perfusion rate, perfusate viscosity, duration of collection, depth of the catheter, length of the tubing and adsorption of hydrophobic molecules to the membrane. To standardize these factors, a robust sampling protocol needs to be established. Microdialysis is applied in healthy and inflamed skin. It enables the in vivo sampling of endogenous and exogenous substances in skin's extracellular ...
Source: Acta Dermato-Venereologica - May 23, 2019 Category: Dermatology Authors: Rea H, Kirby B Tags: Acta Derm Venereol Source Type: research

Novel and Recurrent PNPLA1 Mutations in Spanish Patients with Autosomal Recessive Congenital Ichthyosis; Evidence of a Founder Effect.
This study expands the spectrum of the PNPLA1 disease, which causes variants and demonstrates that the c.417_418delinsTC mutation has founder effects in the Spanish population. PMID: 31120544 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 23, 2019 Category: Dermatology Authors: Esperón-Moldes U, Ginarte Val M, Rodríguez-Pazos L, Fachal L, Azaña JM, Fons MB, Viejo Diaz M, Vega A Tags: Acta Derm Venereol Source Type: research

Satisfaction with Information Provision and Health-related Quality of Life in Basal and Squamous Cell Carcinoma Patients: A Cross-sectional Population-based Study.
PMID: 31120545 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 23, 2019 Category: Dermatology Authors: Waalboer-Spuij R, Hollestein LM, Nijsten TEC, van de Poll-Franse LV Tags: Acta Derm Venereol Source Type: research

Dowling-Degos Disease and Hidradenitis suppurativa. Epidemiological and Clinical Study of 15 patients and Review of the Literature.
lmo J PMID: 31120546 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 23, 2019 Category: Dermatology Authors: Agut-Busquet E, González-Villanueva I, Romani de Gabriel J, Pascual JC, Ribera Pibernat M, Luelmo J Tags: Acta Derm Venereol Source Type: research

Topical Corticosteroid Phobia Among Healthcare Professionals Using the TOPICOP Score.
This study examined corticophobia among healthcare professionals using the Topical Corticosteroid Phobia (TOPICOP) questionnaire. The TOPICOP questionnaire was adapted for use with professionals (TOPICOP-P). Four groups of professionals: pharmacists, paediatricians, general practitioners and dermatologists were observed. The mean global TOPICOP score was 41.9 ± 14.9%. Pharmacists had the highest scores for corticophobia: a global score of 48.5 ± 13.9%, followed by general practitioners, 46.0 ± 13.5%, paediatricians 39.7 ± 14.5%, and dermato...
Source: Acta Dermato-Venereologica - May 17, 2019 Category: Dermatology Authors: Lambrechts L, Gilissen L, Morren MA Tags: Acta Derm Venereol Source Type: research

Dupilumab versus Cyclosporine for Treatment of Moderate-to-Severe Atopic Dermatitis in Adults: Indirect Comparison Using the Eczema Area and Severity Index.
Eckert L Abstract Dupilumab is approved for uncontrolled moderate-to-severe atopic dermatitis (AD), and cyclosporine for severe AD for ≤ 1 year. The efficacy of these treatments was compared indirectly. Regression models used pooled patient-level data to estimate response (Eczema Area and Severity Index (EASI) EASI-50/EASI-75 at weeks 12-16 and 24-30) to dupilumab 300 mg every 2 weeks (weeks; CHRONOS [NCT02260986]) or cyclosporine (University Medical Center). Models were adjusted for sex, baseline EASI, and thymus and activation-regulated chemokine level. A total of 106 patients received dupilumab (+top...
Source: Acta Dermato-Venereologica - May 17, 2019 Category: Dermatology Authors: Ariëns LFM, Gadkari A, van Os-Medendorp H, Ayyagari R, Terasawa E, Kuznik A, Chen Z, Bégo-Le Bagousse G, Lu Y, Rizova E, Graham NMH, Pirozzi G, De Bruin-Weller M, Eckert L Tags: Acta Derm Venereol Source Type: research

Keratitis-Ichthyosis-Deafness Syndrome: Early Death Caused by the GJB2 Mutation p.Gly12Arg.
ier J PMID: 31099403 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 17, 2019 Category: Dermatology Authors: Godillot C, Severino-Freire M, Michaud V, Boralevi F, Labrèze C, Guigonis V, Onnis G, Morice-Picard F, Mazereeuw-Hautier J Tags: Acta Derm Venereol Source Type: research

Smoking does not Alter the Therapy Response to Systemic Anti-psoriatic Therapies: A Two-country, Multi-centre, Prospective, Non-interventional Study.
Abstract Psoriasis can involve the skin, joints, nails and cardiovascular system and result in a significant impairment in quality of life. Studies have shown a lower response rate in smokers, and smoking is a trigger factor for psoriasis. The aim of this study was therefore to analyse the response to systemic therapies for psoriasis, with a focus on smoking. Prospectively collected data from patients with moderate to severe psoriasis included in the national psoriasis registries for Germany and Switzerland (PsoBest and SDNTT) were analysed. Therapy response was defined as reaching a Psoriasis Area and Severity In...
Source: Acta Dermato-Venereologica - May 17, 2019 Category: Dermatology Authors: Anzengruber F, Augustin M, Radtke MA, Thaci D, Yawalkar N, Streit M, Reich K, Drach M, Sorbe C, French LE, Mrowietz U, Maul JT, Itin PH, Navarini AA Tags: Acta Derm Venereol Source Type: research

Economic Burden of Adult Patients with Moderate to Severe Atopic Dermatitis Indicated for Systemic Treatment.
r M Abstract Given the introduction of new therapies targeting specific immune pathways for atopic dermatitis (AD), information on the economic burden of AD patients is needed. Direct costs (medication use and healthcare resource utilization) and costs of productivity loss were studied in 90 adult patients with AD indicated for systemic treatment. Costs were calculated for patients with controlled (Investigator Global Assessment (IGA) 0-2) and uncontrolled (IGA 3-5) disease at inclusion. Mean (95% confidence interval (95% CI)) total direct costs were €5,191 (€4,382-6,019) per patient per year (PPY), &eur...
Source: Acta Dermato-Venereologica - May 10, 2019 Category: Dermatology Authors: Ariëns LFM, van Nimwegen KJM, Shams M, de Bruin DT, van der Schaft J, van Os-Medendorp H, de Bruin Weller M Tags: Acta Derm Venereol Source Type: research

Autochthonous Cutaneous Larva Migrans in France and Europe.
We report here 5 autochthonous cases in France and give an overview of European autochthonous cases. PMID: 31073620 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 10, 2019 Category: Dermatology Authors: Del Giudice P, Hakimi S, Vandenbos F, Magana C, Hubiche T Tags: Acta Derm Venereol Source Type: research

Effect of Omega-3 Supplementation on Quality of Life in Patients with Psoriasis: A Digital Survey-based Study.
rt JR PMID: 31073621 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 10, 2019 Category: Dermatology Authors: Andersen AD, Almegaard A, Ørsted Schultz AN, Zibert JR Tags: Acta Derm Venereol Source Type: research

Interest in Skin Cancer in Urban Populations: A Retrospective Analysis of Google Search Terms in Nine Large German Cities.
k A Abstract Skin cancer is a major public health issue, which could be reduced through prevention programmes. However, prevention utilization is not very prevalent. It is therefore important to understand individuals' interest in skin cancer. Google AdWords Keyword Planner was used to identify the search volume in 9 German cities between July 2014 and June 2018. From a total of 1,203 identified keywords, 1,047 search terms were related to skin cancer, which had an overall search volume of 3,460,980. Most terms referred to "identifying skin cancer". For melanoma, the number of Google searches per 100,000...
Source: Acta Dermato-Venereologica - May 10, 2019 Category: Dermatology Authors: Tizek L, Schielein MC, Rüth M, Szeimies RM, Philipp-Dormston WG, Braun SA, Hecker C, Eberlein B, Biedermann T, Zink A Tags: Acta Derm Venereol Source Type: research

An Unusual Birthmark on the Scalp: A Quiz.
PMID: 31073623 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 10, 2019 Category: Dermatology Authors: Qian YT, Ma JY, Vano-Galvan S, Liu JW, Liu W, Ma DL Tags: Acta Derm Venereol Source Type: research

Palmoplantar Keratoderma and Woolly Hair Revealing Asymptomatic Arrhythmogenic Cardiomyopathy.
PMID: 31073624 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 10, 2019 Category: Dermatology Authors: Guerra L, Magliozzi M, Baban A, di Mambro C, di Zenzo G, Novelli A, El Hachem M, Zambruno G, Castiglia D Tags: Acta Derm Venereol Source Type: research

Granuloma Faciale Treated Successfully with Colchicine.
PMID: 31045232 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 2, 2019 Category: Dermatology Authors: Ohata C, Nakama T Tags: Acta Derm Venereol Source Type: research

Diagnosis of Mycosis Fungoides Following Administration of Dupilumab for Misdiagnosed Atopic Dermatitis.
PMID: 31045233 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 2, 2019 Category: Dermatology Authors: Chiba T, Nagai T, Osada SI, Manabe M Tags: Acta Derm Venereol Source Type: research

Meningeal Carcinomatosis in Advanced Extramammary Paget's Disease: a Case Report.
PMID: 31045234 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 2, 2019 Category: Dermatology Authors: Watanabe A, Onishi M, Tsunoda K, Amano H Tags: Acta Derm Venereol Source Type: research

Coral-bead Skin Lesions Associated with Erosive Arthritis: A Quiz.
PMID: 31045235 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 2, 2019 Category: Dermatology Authors: Orlando G, Dan G, Pezzetta S, Linder D, Salmaso R Tags: Acta Derm Venereol Source Type: research

Expression of CCR3 and CCR4 Suggests a Poor Prognosis in Mycosis Fungoides and S ézary Syndrome.
Expression of CCR3 and CCR4 Suggests a Poor Prognosis in Mycosis Fungoides and Sézary Syndrome. Acta Derm Venereol. 2019 May 02;: Authors: Shono Y, Suga H, Kamijo H, Fujii H, Oka T, Miyagaki T, Shishido-Takahashi N, Sugaya M, Sato S Abstract Tumor cells in cutaneous T cell lymphoma express limited numbers of chemokine receptors. We investigated the expression patterns of CXCR3, CCR3, CCR4 and CCR10 in mycosis fungoides, Sézary syndrome, lym-phomatoid papulosis and anaplastic large cell lymphoma in 121 skin biopsy samples. CXCR3 was expressed in 86% of mycosis fungoides cases but in no an...
Source: Acta Dermato-Venereologica - May 2, 2019 Category: Dermatology Authors: Shono Y, Suga H, Kamijo H, Fujii H, Oka T, Miyagaki T, Shishido-Takahashi N, Sugaya M, Sato S Tags: Acta Derm Venereol Source Type: research

Progressive Erythroderma without Malignancy in the Skin: A Quiz.
PMID: 31037310 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2019 Category: Dermatology Authors: Irie H, Dainichi T, Kaku Y, Kabashima K Tags: Acta Derm Venereol Source Type: research

Novel DSP Spectrin 6 Region Variant Causes Neonatal Erythroderma, Failure to Thrive, Severe Herpes Simplex Infections and Brain Lesions.
We report here a patient with a novel DSP spectrin region (SR) 6 variant c.1756C>T, p.(His586Tyr), novel features of brain lesions and severe recurrent mucocutaneous herpes simplex virus infections, with a favourable response to ustekinumab. Through a review of reported cases of heterozygous variants in DSP SR6 (n = 15) and homozygous or compound heterozygous variants in DSG1 (n = 12) and SAM-like phenotype, we highlight phenotypic variability. Woolly hair, nail abnormalities and cardiomyopathy characterize patients with DSP variants, while elevated immunoglobulin E and food allergies are fre...
Source: Acta Dermato-Venereologica - April 29, 2019 Category: Dermatology Authors: Vakkilainen S, Puhakka L, Klemetti P, Heiskanen K, Seppänen M, Muona M, Posseme C, Darragh D, Väisänen T, Elomaa O, Palomäki M, Saxén H, Ranki A, Hannula-Jouppi K Tags: Acta Derm Venereol Source Type: research

Non-Healing Erythematous, Ulcerated Lesion On The Hand: A Quiz.
PMID: 31037312 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2019 Category: Dermatology Authors: Chlebicka I, Stefaniak A, Woźniak Z, Szepietowski JC Tags: Acta Derm Venereol Source Type: research

Yellowish Nodules on the Vulva in a 6-year-old Girl: A Quiz.
non A PMID: 31037313 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2019 Category: Dermatology Authors: Ackerman M, Maruani A, Estève E, Kerdraon R, Finon A Tags: Acta Derm Venereol Source Type: research

Interdigital Hyalohyphomycosis Caused by Members of the Fusarium solani Species Complex.
PMID: 31037314 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2019 Category: Dermatology Authors: Noguchi H, Matsumoto T, Hiruma M, Kimura U, Yaguchi T, Hirose M, Fukushima S, Ihn H Tags: Acta Derm Venereol Source Type: research

Two Cancer Patients Receiving Dupilumab for Treatment of Atopic Dermatitis.
PMID: 31037315 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2019 Category: Dermatology Authors: Fowler E, Rosen J, Lev-Tov H, Yosipovitch G Tags: Acta Derm Venereol Source Type: research

Therapeutic Efficacy of Etretinate on Cutaneous-type Adult T-cell Leukemia-Lymphoma.
Abstract Cutaneous-type adult T-cell leukemia-lymphoma is treated with antiviral or skin-directed therapy. Medications that are used to treat skin lesions of cutaneous T-cell lymphomas are also used for the cutaneous-type adult T-cell leukemia-lymphoma. Etretinate, a synthetic retinoid, has been used for treating cutaneous T-cell lymphomas; however, its clinical effectiveness for the treatment of cutaneous-type adult T-cell leukemia-lymphoma has not been fully studied. We conducted a retrospective assessment of the efficacy and safety of etretinate in 9 patients with cutaneous-type adult T-cell leukemia-lymphoma. ...
Source: Acta Dermato-Venereologica - April 16, 2019 Category: Dermatology Authors: Yonekura K, Takeda K, Kawakami N, Kanzaki T, Kanekura T, Utsunomiya A Tags: Acta Derm Venereol Source Type: research

Secukinumab Provides Rapid Relief From Itching and Pain in Patients With Moderate-to-Severe Psoriasis: Patient Symptom Diary Data From Two Phase 3, Randomized, Placebo-Controlled Clinical Trials.
PMID: 31017248 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 16, 2019 Category: Dermatology Authors: Yosipovitch G, Soung J, Weiss J, Muscianisi E, Meng X, Gilloteau I, Elewski BE Tags: Acta Derm Venereol Source Type: research

Vitiligo Repigmentation with Melanoma Progression During Pembrolizumab Treatment.
PMID: 31017249 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 16, 2019 Category: Dermatology Authors: Nardin C, Pelletier F, Puzenat E, Aubin F Tags: Acta Derm Venereol Source Type: research

IL-17A Inhibitor Switching - Efficacy of Ixekizumab Following Secukinumab Failure. A Single-Center Experience.
We report the experience (2017-2018) of a tertiary medical center with interleukin-17A-inhibitor switch in patients with moderate-to-severe psoriasis. Patient-, disease- and outcome-related data were retrospectively collected from the electronic files of 25 patients switched to ixekizumab following secukinumab failure. Mean ± standard deviation patient age was 56.7 ± 12.2 years. Mean baseline Psoriasis Area and Severity Index was 25. Secukinumab was discontinued due to primary failure in 7 patients and secondary failure in 18. Ixekizumab was administered for 7.3 ±&thi...
Source: Acta Dermato-Venereologica - April 16, 2019 Category: Dermatology Authors: Sherman S, Cohen ES, Amitay-Laish I, Hodak E, Pavlovsky L Tags: Acta Derm Venereol Source Type: research

Systemic Lupus Erythematosus with Familial Mediterranean Fever: Case Report and Review of Literature.
PMID: 31017251 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 16, 2019 Category: Dermatology Authors: Kokubu H, Ida H, Tanaka T, Fujimoto N Tags: Acta Derm Venereol Source Type: research

Sunbed Use Increases Cutaneous Squamous Cell Carcinoma Risk in Women: A Large-scale, Prospective Study in Sweden.
Abstract The incidence of cutaneous squamous cell carcinoma has increased rapidly in Sweden in the past decades. Here, we present a prospective study of the Melanoma in Southern Sweden (MISS)-cohort, with 29,460 participating women in southern Sweden that investigates the risk factors for cutaneous squamous cell carcinoma. Data on the host and skin cancer risk factors were collected through questionnaires and then matched with the National Cancer Registry. Statistical analyses were based on uni- and multivariable Cox proportional hazards models, using age as the time-scale. We found that sunbed use (hazard ratio (...
Source: Acta Dermato-Venereologica - April 16, 2019 Category: Dermatology Authors: Christensen GB, Ingvar C, Hartman LW, Olsson H, Nielsen K Tags: Acta Derm Venereol Source Type: research

Dupilumab Improved Alopecia Areata in a Patient with Atopic Dermatitis: A Case Report.
PMID: 30938821 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 2, 2019 Category: Dermatology Authors: Uchida H, Kamata M, Watanabe A, Agematsu A, Nagata M, Fukaya S, Hayashi K, Fukuyasu A, Tanaka T, Ishikawa T, Ohnishi T, Tada Y Tags: Acta Derm Venereol Source Type: research

Mucosal Lichen Planus Mimicking Mucosal Lesions in Stevens-Johnson Syndrome after Nivolumab Therapy.
PMID: 30938822 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 2, 2019 Category: Dermatology Authors: Miyagawa F, Nakajima A, Ohyama SI, Aoki Y, Nishikawa M, Nakamura Y, Hashimoto T, Asada H Tags: Acta Derm Venereol Source Type: research

Itch in Patients with Acute Heart Failure.
PMID: 30938823 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 2, 2019 Category: Dermatology Authors: Ponikowska M, Biegus J, Zymlinski R, Szepietowski JC Tags: Acta Derm Venereol Source Type: research

Mutation in FAM111B Causes Hereditary Fibrosing Poikiloderma with Tendon Contracture, Myopathy, and Pulmonary Fibrosis.
PMID: 30938824 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 2, 2019 Category: Dermatology Authors: Chen F, Zheng L, Li Y, Li H, Yao Z, Li M Tags: Acta Derm Venereol Source Type: research

Erythropoietic Protoporphyria in a Japanese Population.
Abstract Erythropoietic protoporphyria is caused by a partial deficiency of ferrochelatase, which is the last enzyme in the heme biosynthesis pathway. In a typical erythropoietic protoporphyria, photosensitivity initially appears, following the first exposure to the sun in early infancy or childhood. Erythropoietic protoporphyria has been reported worldwide, but there is a regional variation in its epidemiology. Approximately 20% of the Japanese patients were recognized to have symptoms of erythropoietic protoporphyria after 10 years of age. Physicians occasionally encounter Japanese patients with erythropoietic p...
Source: Acta Dermato-Venereologica - April 2, 2019 Category: Dermatology Authors: Mizawa M, Makino T, Nakano H, Sawamura D, Shimizu T Tags: Acta Derm Venereol Source Type: research

Sensory Qualities Point to Different Structural and Functional Skin Patterns in Chronic Pruritus Patients. A Translational Explorative Study.
r S Abstract Chronic pruritus (CP) is often accompanied by paresthetic sensations like warmth, burning and stinging. The aim of this study was to analyze, whether divergent sensations are linked to structural and functional skin alterations in clinically diagnosed CP patients. Clinical responses to capsaicin, histamine, and to thermal and mechanical stimulation, intraepidermal nerve fiber density, and epidermal expression of transient receptor potential (TRP)-channels were investigated in healthy controls, and in CP patients, reporting either warmth (CP-W) or neuropathic sensations (CP-N). In CP-W, pinprick hypera...
Source: Acta Dermato-Venereologica - April 2, 2019 Category: Dermatology Authors: Hidding J, Agelopoulos K, Pereira MP, Conrad H, Hatt H, Lotts T, Osada N, Pogatzki-Zahn E, Schmelz M, Ständer S Tags: Acta Derm Venereol Source Type: research