Aortic valve surgery and left ventricular assist device: lights and shadows. Letter regarding the article ‘Survival following a concomitant aortic valve procedure during left ventricular assist device surgery: an ISHLT Mechanically Assisted Circulatory Support (IMACS) Registry analysis’
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 11, 2021 Category: Cardiology Authors: Claudia Loardi, Marco Zanobini Tags: Letter to the Editor Source Type: research

Peripheral and Pulmonary Effects of Inorganic ‐Nitrite during Exercise in Heart Failure with Preserved Ejection Fraction
ConclusionSodium nitrite enhances skeletal muscle O2 conductance during exercise as well as pulmonary O2 diffusion, optimizing O2 kinetics in tandem with increased convective O2 delivery through cardiac output augmentation. The favorable combined pulmonary, cardiac and peripheral effects of nitrite may improve exercise tolerance in people with HFpEF and requires further investigation. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 9, 2021 Category: Cardiology Authors: Yogesh N. V. Reddy, Glenn M. Stewart, Masaru Obokata, Katlyn E. Koepp, Barry A. Borlaug Tags: Research Article Source Type: research

Renin ‐angiotensin‐aldosterone inhibitors and COVID‐19: nearing the end of a media‐fuelled controversy
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 9, 2021 Category: Cardiology Authors: Daniela Tomasoni, Mark C Petrie, Marianna Adamo, Marco Metra Tags: Editorial Comment Source Type: research

Oral Sucrosomial iron improves exercise capacity and quality of life in heart failure with reduced ejection fraction and iron deficiency: A non ‐randomized, open‐label, proof‐of‐concept study
AbstractBackgroundOral sucrosomial iron (SI) combines enhanced bioavailability and tolerance compared to conventional oral iron along with similar efficacy compared to intravenous iron in several conditions associated with iron deficiency (ID).Methods and ResultsIn this non ‐randomized, open‐label study, we sought to evaluate prospectively the effects of SI on clinical parameters, exercise capacity and quality of life in 25 heart failure patients with reduced ejection fraction (HFrEF) and ID, treated with SI 28 mg daily for 3 months, in comparison to 25 matched HFrEF controls. All patients were on optimal...
Source: European Journal of Heart Failure - January 9, 2021 Category: Cardiology Authors: Apostolos Karavidas, Efstratios Troganis, George Lazaros, Despina Balta, Ioannis ‐Nektarios Karavidas, Eftihia Polyzogopoulou, John Parissis, Dimitrios Farmakis Tags: Research Article Source Type: research

The advantages, pitfalls and limitations of guideline ‐directed medical therapy in patients with valvular heart disease
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 9, 2021 Category: Cardiology Authors: Harminder Gill, Omar Chehab, Christopher Allen, Tiffany Patterson, Simon Redwood, Ronak Rajani, Bernard Prendergast Tags: Viewpoint Source Type: research

Cardiac Myosin ‐Binding Protein C in the Diagnosis and Risk Stratification of Acute Heart Failure
AbstractAimsCardiac myosin ‐binding protein C (cMyC) seems to be even more sensitive in the quantification of cardiomyocyte injury versus high‐sensitivity cardiac troponin (hs‐cTn), and may therefore have diagnostic and prognostic utility.Methods and resultsIn a prospective multicentre diagnostic study, cMyC, hs ‐cTnT, and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) plasma concentrations were measured in blinded fashion in patients presenting to the emergency department with acute dyspnoea. Two independent cardiologists centrally adjudicated the final diagnosis. Diagnostic accuracy for a cute hear...
Source: European Journal of Heart Failure - January 9, 2021 Category: Cardiology Authors: Nikola Kozhuharov, Desiree Wussler, Thomas Kaier, Ivo Strebel, Samyut Shrestha, Dayana Flores, Albina Nowak, Zaid Sabti, Thomas Nestelberger, Tobias Zimmermann, Joan Walter, Maria Belkin, Eleni Michou, Pedro Lopez Ayala, Danielle M. Gualandr Tags: Research Article Source Type: research

Characterization of NT ‐PROBNP in a large cohort of COVID‐19 patients
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 9, 2021 Category: Cardiology Authors: Juan Caro ‐Codón, Juan R. Rey, Antonio Buño, Angel M. Iniesta, Sandra O. Rosillo, Sergio Castrejon‐Castrejon, Laura Rodriguez‐Sotelo, Luis A. Martinez, Irene Marco, Carlos Merino, Lorena Martin‐Polo, Jose M. Garcia‐Veas, Marcel Mar Tags: Research Article Source Type: research

Circulating cardiovascular microRNAs in critically ill COVID ‐19 patients Short title: microRNA signatures in COVID‐19
ConclusionIn this exploratory study, inflammation and cardiac myocyte ‐specific miRs were upregulated in critically ill COVID‐19 patients. Importantly, miR profiles were able to differentiate between severely ill, mechanically‐ventilated Influenza‐ARDS and COVID‐19 patients, indicating a rather specific response and cardiac involvement of COVID‐19. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 9, 2021 Category: Cardiology Authors: Ankita Garg, Benjamin Seeliger, Anselm A. Derda, Ke Xiao, Anika Gietz, Kristian Scherf, Kristina Sonnenschein, Isabell Pink, Marius M. Hoeper, Tobias Welte, Johann Bauersachs, Sascha David, Christian B är, Thomas Thum Tags: Research Article Source Type: research

Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double ‐blind, randomized, placebo‐controlled clinical trial
ConclusionIntravenous immunoglobulin therapy does not significantly improve cardiac systolic function or functional capacity beyond standard medical therapy in patients with idiopathic chronic DCM and cardiac B19V persistence.Clinical Trial Registration:ClinicalTrials.gov ID NCT00892112. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 7, 2021 Category: Cardiology Authors: Mark R. Hazebroek, Michiel T.H.M. Henkens, Anne G. Raafs, Job A.J. Verdonschot, Jort J. Merken, Robert M. Dennert, Casper Eurlings, Myrurgia A. Abdul Hamid, Petra F.G. Wolffs, Bjorn Winkens, Hans ‐Peter Brunner‐La Rocca, Christian Knacksted Tags: Research Article Source Type: research

Empagliflozin and renal sodium handling: an intriguing smart osmotic diuretic
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 7, 2021 Category: Cardiology Authors: Wilfried Mullens, Pieter Martens Tags: Editorial Comment Source Type: research

COVID ‐19 acute respiratory distress syndrome: intriguing haemodynamics of an intriguing syndrome
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 7, 2021 Category: Cardiology Authors: Nick Smith, Emmanouil Tampakakis Tags: Editorial Comment Source Type: research

Letter regarding the article ‘Effects of hyperkalaemia and non‐adherence to renin–angiotensin–aldosterone system inhibitor therapy in patients with heart failure in Italy: a propensity‐matched study’
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 5, 2021 Category: Cardiology Authors: Hidenori Moriyama, Takashi Kohno, Shun Kohsaka Tags: Letter to the Editor Source Type: research

Improving female enrolment in randomized clinical trials of heart failure with reduced ejection fraction to ensure evidence ‐based health care recommendations
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 5, 2021 Category: Cardiology Authors: Birke Schneider, Peter Ong Tags: Editorial Comment Source Type: research

SOLOIST ‐WHF and updated meta‐analysis: sodium–glucose co‐transporter 2 inhibitors should be initiated in patients hospitalized with worsening heart failure
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 29, 2020 Category: Cardiology Authors: Kieran F. Docherty, John J.V. McMurray Tags: Viewpoint Source Type: research

A mechanistic rationale for the investigation of SGLT2 inhibitors in HFpEF ‐ Letter regarding the article 'Baseline Characteristics of Patients with Heart Failure with Preserved Ejection Fraction in the EMPEROR‐Preserved Trial'
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 29, 2020 Category: Cardiology Authors: Steffen Pabel, Nazha Hamdani, Samuel Sossalla Tags: Letter to the Editor Source Type: research

The Labyrinth of Nomenclature in Cardiology. Eternal Dilemmas and New Challenges on the Horizon in the Personalized Medicine Era
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 29, 2020 Category: Cardiology Authors: Gherardo Finocchiaro, Gianfranco Sinagra, Michael Papadakis, Gerald Carr ‐White, Antonis Pantazis, Sanjay Sharma, Iacopo Olivotto, Claudio Rapezzi Tags: Viewpoint Source Type: research

The hyperdynamic circulatory profile of patients with COVID ‐19‐related AVDS. Letter regarding the article untitled” Haemodynamic characteristics of COVID‐19 patients with acute respiratory distress syndrome requiring mechanical ventilation. An invasive assessment using right heart catheterization”
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 29, 2020 Category: Cardiology Authors: Yazine Mahjoub, Daniel Oscar Rodenstein, Vincent Jounieaux Tags: Letter to the Editor Source Type: research

Aortic valve surgery and left ventricular assist device: lights and shadows
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 29, 2020 Category: Cardiology Authors: Claudia Loardi, Marco Zanobini Tags: Letter to the Editor Source Type: research

COVID ‐19 ARDS: Intriguing hemodynamics of an intriguing syndrome
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 29, 2020 Category: Cardiology Authors: Nick Smith, Emmanouil Tampakakis Tags: Editorial Comment Source Type: research

Empagliflozin and renal sodium handling; an intriguing smart osmotic diuretic
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 28, 2020 Category: Cardiology Authors: Wilfried Mullens, Pieter Martens Tags: Editorial Comment Source Type: research

Dynamics of Myocardial Fibrosis After Left Ventricular Assist Device Implantation: Should Speeding Up the Scar Have Us Scared Stiff?
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 28, 2020 Category: Cardiology Authors: Rabea Asleh, Offer Amir, Sudhir S. Kushwaha Tags: Editorial Comment Source Type: research

Effects of dapagliflozin in heart failure with reduced ejection fraction, and COPD: An analysis of DAPA ‐HF
We examined whether the effects of dapagliflozin in DAPA ‐HF were modified by COPD status. The primary outcome was the composite of an episode of worsening heart failure (HF) event or cardiovascular (CV) death.585 (12.3%) of the 4744 patients randomized had a history of COPD. Patients with COPD were more likely to be older men with a history of smoking, worse renal function, and higher baseline NT ‐proBNP, and less likely to be treated with a beta‐blocker or mineralocorticoid receptor antagonist. The incidence of the primary outcome was higher in patients with COPD than in those without 18.9 (95% CI 16.0–22.2) ...
Source: European Journal of Heart Failure - December 23, 2020 Category: Cardiology Authors: Pooja Dewan, Kieran F Docherty, Olof Bengtsson, Rudolf A Boer, Akshay S Desai, Jaroslaw Drozdz, Nathaniel M Hawkins, Silvio E Inzucchi, Masafumi Kitakaze, Lars K øber, Mikail N Kosiborod, Anna M Langkilde, Daniel Lindholm, Felipe A Martinez, Tags: Research Article Source Type: research

The importance of electrocardiographic follow ‐up in heart failure
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 22, 2020 Category: Cardiology Authors: Kevin Vernooy, Hans ‐Peter Brunner‐La Rocca Tags: Editorial Comment Source Type: research

Intravenous Immunoglobulin Therapy in Adult Patients with Chronic Idiopathic Cardiomyopathy and Cardiac Parvovirus B19 persistence
ConclusionIVIg therapy does not significantly improve cardiac systolic function or functional capacity beyond standard medical therapy in patients with idiopathic chronic DCM and cardiac B19V persistence. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 21, 2020 Category: Cardiology Authors: Mark R. Hazebroek, Michiel T.H.M. Henkens, Anne G. Raafs, Job A.J. Verdonschot, Jort J. Merken, Robert M. Dennert, Casper Eurlings, Myrurgia A. Abdul Hamid, Petra F.G. Wolffs, Bjorn Winkens, Hans ‐Peter Brunner‐La Rocca, Christian Knacksted Tags: Research Article Source Type: research

Pulmonary Artery Pulsatility Index Predicts Right Ventricular Myofilament Dysfunction in Advanced Human Heart Failure
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 21, 2020 Category: Cardiology Authors: M. Imran Aslam, Vivek Jani, Brian Lin, Brittany Dunkerly ‐Eyring, Carissa E. Livingston, Abhinay Ramachandran, Mark Ranek, Kenneth C. Bedi, Kenneth B. Margulies, David A. Kass, Steven Hsu Tags: Research Letter Source Type: research

Intravenous Immunoglobulin Therapy in Adult Patients with Chronic Idiopathic Cardiomyopathy and Cardiac Parvovirus B19 persistence
ConclusionIVIg therapy does not significantly improve cardiac systolic function or functional capacity beyond standard medical therapy in patients with idiopathic chronic DCM and cardiac B19V persistence. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 21, 2020 Category: Cardiology Authors: Mark R. Hazebroek, Michiel T.H.M. Henkens, Anne G. Raafs, Job A.J. Verdonschot, Jort J. Merken, Robert M. Dennert, Casper Eurlings, Myrurgia A. Abdul Hamid, Petra F.G. Wolffs, Bjorn Winkens, Hans ‐Peter Brunner‐La Rocca, Christian Knacksted Tags: Research Article Source Type: research

Pulmonary Artery Pulsatility Index Predicts Right Ventricular Myofilament Dysfunction in Advanced Human Heart Failure
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 21, 2020 Category: Cardiology Authors: M. Imran Aslam, Vivek Jani, Brian Lin, Brittany Dunkerly ‐Eyring, Carissa E. Livingston, Abhinay Ramachandran, Mark Ranek, Kenneth C. Bedi, Kenneth B. Margulies, David A. Kass, Steven Hsu Tags: Research Letter Source Type: research

How To Attr ‐Act The Perfect Match?
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 20, 2020 Category: Cardiology Authors: Diana Bonderman Tags: Editorial Comment Source Type: research

Letter regarding the article ‘Efficacy and safety of tafamidis doses in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR‐ACT) and long‐term extension study’
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Thibaud Damy, Marla B. Sultan, Ronald Witteles Tags: Letter to the Editor Source Type: research

Letter regarding the article “Effects of hyperkalemia and non‐adherence to renin angiotensin aldosterone system inhibitors (RAASi) in patients affected by heart failure in Italy: a propensity‐matched study”
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Hidenori Moriyama, Takashi Kohno, Shun Kohsaka Tags: Letter to the Editor Source Type: research

Is Acute heart failure a distinctive disorder? An analysis from BIOSTAT ‐CHF
ConclusionThe study identifies different characteristics and predictors of outcome in acute HF patients as compared to outpatients with chronic HF developing worsening HF. The markers identified may be useful in better diagnosing acute HF and may become targets for treatment development. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Beth A. Davison, Stefanie Senger, Iziah E. Sama, Gary G. Koch, Alexandre Mebazaa, Kenneth Dickstein, Nilesh J. Samani, Marco Metra, Stefan D. Anker, John G. Cleland, Leong L. Ng, Ify R Mordi, Faiez Zannad, Gerasimos S. Filippatos, Hans L. Hi Tags: Review Source Type: research

Improving female enrolment in randomized clinical trials of HFrEF to ensure evidence ‐based health care recommendations
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Birke Schneider, Peter Ong Tags: Editorial Comment Source Type: research

Arrhythmias in cancer: Rhythm is gonna get you!
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Dimitrios Farmakis, Gerasimos Filippatos Tags: Editorial Comment Source Type: research

Letter regarding the article ‘Efficacy and safety of tafamidis doses in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR‐ACT) and long‐term extension study’
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Thibaud Damy, Marla B. Sultan, Ronald Witteles Tags: Letter to the Editor Source Type: research

Letter regarding the article “Effects of hyperkalemia and non‐adherence to renin angiotensin aldosterone system inhibitors (RAASi) in patients affected by heart failure in Italy: a propensity‐matched study”
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Hidenori Moriyama, Takashi Kohno, Shun Kohsaka Tags: Letter to the Editor Source Type: research

Is Acute heart failure a distinctive disorder? An analysis from BIOSTAT ‐CHF
ConclusionThe study identifies different characteristics and predictors of outcome in acute HF patients as compared to outpatients with chronic HF developing worsening HF. The markers identified may be useful in better diagnosing acute HF and may become targets for treatment development. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Beth A. Davison, Stefanie Senger, Iziah E. Sama, Gary G. Koch, Alexandre Mebazaa, Kenneth Dickstein, Nilesh J. Samani, Marco Metra, Stefan D. Anker, John G. Cleland, Leong L. Ng, Ify R Mordi, Faiez Zannad, Gerasimos S. Filippatos, Hans L. Hi Tags: Review Source Type: research

Improving female enrolment in randomized clinical trials of HFrEF to ensure evidence ‐based health care recommendations
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Birke Schneider, Peter Ong Tags: Editorial Comment Source Type: research

Arrhythmias in cancer: Rhythm is gonna get you!
European Journal of Heart Failure, Accepted Article. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 19, 2020 Category: Cardiology Authors: Dimitrios Farmakis, Gerasimos Filippatos Tags: Editorial Comment Source Type: research

Coronary microvascular dysfunction in heart failure with preserved ejection fraction: not the end but the end of the beginning
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 16, 2020 Category: Cardiology Authors: Domenico D'Amario, Josip A. Borovac, Filippo Crea Tags: Editorial Comment Source Type: research

OUTSTEP ‐HF: Randomised controlled trial comparing short‐term effects of sacubitril/valsartan versus enalapril on daily physical activity in patients with chronic heart failure with reduced ejection fraction
ConclusionAfter 12  weeks of treatment, there was no significant benefit of sacubitril/valsartan on either 6MWT or in daytime physical activity measured by actigraphy compared with enalapril. (ClinicalTrials.gov number, NCT02900378). (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 14, 2020 Category: Cardiology Authors: Massimo F. Piepoli, Rizwan I. Hussain, Josep Comin ‐Colet, Ramon Dosantos, Philippe Ferber, Tiny Jaarsma, Frank Edelmann Tags: Research Article Source Type: research

Patterns of unplanned readmissions after heart failure hospitalization: novel longitudinal perspectives from Australia and New Zealand
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 11, 2020 Category: Cardiology Authors: Christian Madelaire, S øren Lund Kristensen Tags: Editorial Comment Source Type: research

COVID ‐19, myocarditis, and the other side of the bed
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 10, 2020 Category: Cardiology Authors: Emer Joyce Tags: Viewpoint Source Type: research

Worsening renal function after diuresis among heart failure patients with preserved ejection fraction: a dilemma to heart failure management: Reply
European Journal of Heart Failure, EarlyView. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - December 10, 2020 Category: Cardiology Authors: Barry Greenberg, Satit Janvanishstaporn, Siting Feng Tags: Letter to the Editor Source Type: research