Guideline ‐directed medical therapy for heart failure: The key ingredient for successful in‐hospital and post‐discharge care
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 31, 2024 Category: Cardiology Authors: Muhammad Shahzeb Khan, Gregg C. Fonarow, Stephen J. Greene Tags: Invited Editorial Source Type: research

Natriuretic peptides  – Biomarker companions through thick and thin
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 30, 2024 Category: Cardiology Authors: Micha T. Maeder Tags: Invited Editorial Source Type: research

Expanding the knowledge on transthyretin p.V142I variant ‐related cardiomyopathy
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 29, 2024 Category: Cardiology Authors: Emanuele Monda, Giuseppe Limongelli Tags: Invited Editorial Source Type: research

Deep phenotyping of p.(V142I) ‐associated variant transthyretin amyloid cardiomyopathy: Distinct from wild‐type transthyretin amyloidosis?
Conclusionp.(V142I)-ATTRv-CM has an aggressive phenotype characterized by myocyte loss and widespread myocardial infiltration which may account for frequent biventricular failure and poor prognosis in this ATTR-CM genotypic subgroup. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 28, 2024 Category: Cardiology Authors: Yousuf Razvi, Adam Ioannou, Rishi K. Patel, Liza Chacko, Nina Karia, Mattia Riefolo, Aldostefano Porcari, Muhammad Umaid Rauf, Neasa Starr, Sashiananthan Ganesananthan, Iona Blakeney, Nandita Kaza, Stefano Filisetti, Roos Eline Bolhuis, Doro Tags: Research Article Source Type: research

Atrial myopathy and heart failure with preserved ejection fraction: When a label does more harm than good?
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 28, 2024 Category: Cardiology Authors: Pierpaolo Pellicori, John G.F. Cleland Tags: Invited Editorial Source Type: research

Advantage of uptitration of foundational heart failure drugs in heart failure with reduced ejection fraction and low blood pressure
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 25, 2024 Category: Cardiology Authors: Roger Hullin Tags: Invited Editorial Source Type: research

Integration of implantable device therapy in patients with heart failure. A clinical consensus statement from the Heart Failure Association (HFA) and European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC)
Implantable devices form an integral part of the management of patients with heart failure (HF) and provide adjunctive therapies in addition to cornerstone drug treatment. Although the number of these devices is growing, only few are supported by robust evidence. Current devices aim to improve haemodynamics, improve reverse remodelling, or provide electrical therapy. A number of these devices have guideline recommendations and some have been shown to improve outcomes such as cardiac resynchronization therapy, implantable cardioverter-defibrillators and long-term mechanical support. For others, more evidence is still needed...
Source: European Journal of Heart Failure - January 25, 2024 Category: Cardiology Authors: Wilfried Mullens, Jeroen Dauw, Finn Gustafsson, Alexandre Mebazaa, Jan Steffel, Klaus K. Witte, Victoria Delgado, Cecilia Linde, Kevin Vernooy, Stefan D. Anker, Ovidiu Chioncel, Davor Milicic, Gerd Hasenfu ß, Piotr Ponikowski, Ralph Stephan Tags: Position Paper Source Type: research

Efficacy and safety of CDR132L in patients with reduced left ventricular ejection fraction after myocardial infarction: Rationale and design of the HF ‐REVERT trial
ConclusionThe HF-REVERT trial may underpin the concept of miR-132 inhibition to prevent or reverse cardiac remodelling in post-MI HF. The results will inform the design of subsequent outcome trials to test CDR132L in HF. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 25, 2024 Category: Cardiology Authors: Johann Bauersachs, Scott D. Solomon, Stefan D. Anker, Isabel Antorrena ‐Miranda, Sandor Batkai, Janika Viereck, Steffen Rump, Gerasimos Filippatos, Ulrich Granzer, Piotr Ponikowski, Rudolf A. de Boer, Orly Vardeny, Wilfried Hauke, Thomas Th Tags: Study Design Source Type: research

Phenotypic characterization of heart failure with preserved ejection fraction. Letter regarding the article ‘Disproportionate exercise‐induced pulmonary hypertension in relation to cardiac output in heart failure with preserved ejection fraction: A non‐invasive echocardiographic study’
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 23, 2024 Category: Cardiology Authors: Ajay Kumar Jha Tags: LETTER TO THE EDITOR Source Type: research

Issue Information
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 23, 2024 Category: Cardiology Tags: ISSUE INFORMATION Source Type: research

December 2023 at a glance: Focus on medical therapy in chronic and acute heart failure
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 23, 2024 Category: Cardiology Authors: Daniela Tomasoni, Marianna Adamo, Marco Metra Tags: INTRODUCTION Source Type: research

Myocardial sodium –glucose cotransporter 2 expression and cardiac remodelling in patients with severe aortic stenosis: The BIO‐AS study
ConclusionIn patients with LF-LG AS, SGLT2 gene and protein were hyper-expressed in cardiomyocytes and associated with myocardial fibrosis, inflammation, and oxidative stress. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 22, 2024 Category: Cardiology Authors: Lucia Scisciola, Pasquale Paolisso, Marta Belmonte, Emanuele Gallinoro, Leen Delrue, Fatemeh Taktaz, Rosaria Anna Fontanella, Ivan Degrieck, Ada Pesapane, Filip Casselman, Armando Puocci, Martina Franzese, Frank Van Praet, Michele Torella, R Tags: Research Article Source Type: research

Neuromodulation interventions in the management of heart failure
AbstractDespite remarkable improvements in the management of heart failure (HF), HF remains one of the most rapidly growing cardiovascular condition resulting in a substantial burden on healthcare systems worldwide. In clinical practice, however, a relevant proportion of patients are treated with suboptimal combinations and doses lower than those recommended in the current guidelines. Against this background, it remains important to identify new targets and investigate additional therapeutic options to alleviate symptoms and potentially improve prognosis in HF. Therefore, non-pharmacological interventions targeting autonom...
Source: European Journal of Heart Failure - January 22, 2024 Category: Cardiology Authors: Amr Abdin, Lucas Lauder, Marat Fudim, William T. Abraham, Stefan D. Anker, Michael B öhm, Felix Mahfoud Tags: Review Article Source Type: research

Worsening heart failure comes into focus, chronic heart failure takes a backseat
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 22, 2024 Category: Cardiology Authors: Maribel Gonz ález‐Del‐Hoyo, Xavier Rossello Tags: Invited Editorial Source Type: research

Breaking down peripartum cardiomyopathy: A learning adventure. Letter regarding the article ‘Outcomes at 1 year in women with peripartum cardiomyopathy: Findings from the ESC EORP PPCM Registry’
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - January 22, 2024 Category: Cardiology Authors: Andreas S. Papazoglou, Ana Rita Leite Tags: Letter to the Editor Source Type: research