Do electrical current and laser therapies improve bone remodeling during an orthodontic treatment with corticotomy?
ConclusionsLow-level laser therapy (LLLT) and MC application both improved the process of bone remodeling during orthodontic treatment with corticotomy. Still, electrical current therapy promoted a more effective tooth displacement but presented expected root resorption similar to all experimental treatments.Clinical relevanceIt is important to know the effects of minimally invasive therapies on cellular and molecular elements involved in the bone remodeling of orthodontic treatment associated with corticotomy surgery, in order to reduce the adverse effects in the use of this technique and to establish a safer clinical rou...
Source: Clinical Oral Investigations - February 15, 2019 Category: Dentistry Source Type: research

Relationship between periodontal inflammation and calcium channel blockers induced gingival overgrowth —a cross-sectional study in a Japanese population
AbstractObjectivesPeriodontal inflammation is regarded as a risk factor for drug-induced gingival overgrowth (DIGO). In order to elucidate the involvement of periodontal inflammation in DIGO, the periodontal status of subjects who do not develop DIGO despite receiving causative drugs (non-responders) needs to be examined. Therefore, the aim of the present study which was a pilot study was to assess periodontal inflammatory variables in responders (calcium channel blocker induced-GO patients), non-responders, and patients who did not receive causative drugs (non-consumers).Materials and methodsThe following parameters were ...
Source: Clinical Oral Investigations - February 15, 2019 Category: Dentistry Source Type: research

Different light-activation systems associated with dental bleaching: a systematic review and a network meta-analysis
ConclusionNo type of light-activated in-office bleaching was superior to light-free in-office bleaching for both high- and low-concentrate in-office bleaching gels (PROSPERO —CRD42017078743).Clinical relevanceAlthough many times dental professionals use “laser whitening” as a form of marketing, this study confirmed that no type of light-activation for in-office bleaching can improve the bleaching efficacy. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - February 14, 2019 Category: Dentistry Source Type: research

Effectiveness of the ozone application in two-visit indirect pulp therapy of permanent molars with deep carious lesion: a randomized clinical trial
AbstractObjectivesThe aim of this randomized, three-arm parallel, single-blinded clinical trial was to evaluate the clinical and microbiological effectiveness of the ozone application in two-visit indirect pulp therapy.Materials and methodsOne hundred five lower first molar teeth with deep caries lesion were included and randomly assigned three groups to apply the two-visit indirect pulp therapy. Treatment procedure was applied without any disinfectant (control), with 60-s 2% chlorhexidine digluconate (CHX) or 60-s ozone application. In four different stages (after initial excavation, ozone/CHX application before the tempo...
Source: Clinical Oral Investigations - February 13, 2019 Category: Dentistry Source Type: research

Different surface modifications combined with universal adhesives: the impact on the bonding properties of zirconia to composite resin cement
AbstractObjectiveThe purpose of this study was to analyze the impact of plasma treatment and (universal adhesives) UAs on the bonding properties of zirconia.Material and methodsZirconia specimens (N = 744;n = 186/pretreatment) were prepared, highly polished, and pretreated: (i) plasma (oxygen plasma, 10s, 5 mm), (ii) airborne-particle abrasion (alumina, 50 μm, 0.05 MPa, 5 s, 10 mm), (iii) airborne-particle abrasion + plasma, and (iv) without pretreatment (highly polished surface). Surface ro ughness (Ra) and surface free energy (SFE) were measured (n = 6...
Source: Clinical Oral Investigations - February 12, 2019 Category: Dentistry Source Type: research

Both non-surgical dental treatment and extractions increase the risk of medication-related osteonecrosis of the jaw: case-control study
AbstractObjectivesMedication-related osteonecrosis of the jaws (MRONJ) is a serious condition whose risk factors remain unclear. The aim of this study is to investigate the role of oral health and of dental treatment in the development of MRONJ.Materials and methodsA case-control study was conducted in Brisbane, Australia. Hospital records were used to identify incident cases of MRONJ between January 2010 and March 2017. Cases were individually matched to up to 3 controls according to age, sex, primary disease, and type of antiresorptive therapy. Demographic data, medical histories and public dental records were collected....
Source: Clinical Oral Investigations - February 12, 2019 Category: Dentistry Source Type: research

Polymerization pattern characterization within a resin-based composite cured using different curing units at two distances
AbstractObjectivesTo investigate the relationship of the irradiance-beam-profile areas from six different light-curing units (LCUs) with the degree of conversion (DC), microhardness (KH), and cross-link density (CLD) throughout a resin-based composite (RBC) cured at two clinically relevant distances, and to explore the correlations among them.Materials and methodsA mapping approach was used to measure DC using micro-Raman spectroscopy, KH using a Knoop indentor on a hardness tester, and %KH reduction after ethanol exposure, as an indicator for CLD within a nano-hybrid RBC increment (n = 3) at various depths. ...
Source: Clinical Oral Investigations - February 9, 2019 Category: Dentistry Source Type: research

Visibility, location, and morphology of the primary maxillary sinus ostium and presence of accessory ostia: a retrospective analysis using cone beam computed tomography (CBCT)
ConclusionsMost of the analyzed maxillary sinus cavities in the present population had a patent PMO. Being male and having morphological changes of the sinus mucosa were factors associated with a reduced prevalence of a patent PMO.Clinical relevanceA maxillary sinus with pathological findings of the mucosa seems to have a reduced prevalence of patent PMOs. Therefore, clinicians should take care to assess any clinical and radiographical sign indicating a potential maxillary sinusitis prior to surgical interventions in this region, especially in cases with planned sinus floor elevation. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - February 9, 2019 Category: Dentistry Source Type: research

Microbiological dynamics of red complex bacteria following full-mouth air polishing in periodontally healthy subjects —a randomized clinical pilot study
AbstractObjectivesSuppression of periodontal pathogens in the oral cavity of periodontally healthy individuals may lower the risk for periodontal or periimplant diseases. Therefore, the present study aimed to analyze the effect of supragingival debridement (SD) with adjunctive full mouth glycine powder air polishing (FM-GPAP) on the prevalence of periodontal pathogens in periodontally healthy individuals.Materials and MethodsEighty-seven systemically and periodontally healthy intraoral carriers of red complex bacteria, i.e.,Porphyromonas gingivalis,Tannerella forsythia, andTreponema denticola or other periodontal pathogens...
Source: Clinical Oral Investigations - February 6, 2019 Category: Dentistry Source Type: research

Can lithium disilicate ceramic crowns be fabricated on the basis of CBCT data?
ConclusionsThe marginal fit of EOS and IOS, IOS and CBCT 2, and CBCT 2 and CBCT 1 showed statistical differences. The marginal fit of CBCT 1 and CBCT 2 is within the range of clinical acceptance; however, it is significant inferior to EOS and IOS.Clinical relevanceThe use of a CBCT enables clinicians to digitize conventional impressions. Despite presenting results within clinical acceptable levels, the CBCT base method seems to be inferior to Intra-Oral scans or to scanning gypsum models regarding the resulting accuracy and fit. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - February 6, 2019 Category: Dentistry Source Type: research

Correlation of magnetic resonance imaging grades with cytokine levels of synovial fluid of patients with temporomandibular joint disorders: a cross-sectional study
ConclusionsIn patients with TMJ disorders, MRI grades are strongly correlated with NRS scores and levels of cytokines (IL-8, sIL-6R, and sTNF-RI/II) in the synovial fluid.Clinical relevanceJoint effusion scoring can be a reliable and valid indicator for pathological assessment of TMJ disorders. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - February 6, 2019 Category: Dentistry Source Type: research

Evaluation of the effect of teriparatide therapy on mandibular fracture healing in rats with medication-related osteonecrosis of the jaw
ConclusionTeriparatide therapy successfully improved mandibular fracture healing in rats with MRONJ. However, this study was limited by the use of an animal model whose anatomy, physiology, and drug metabolism might be different from humans.Clinical relevanceThe present study showed that teriparatide therapy may be used adjunctive to surgery in the treatment of mandibular fractures in MRONJ patients. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - February 4, 2019 Category: Dentistry Source Type: research

Relationship between the anatomic structures and mandibular posterior teeth for endodontic surgery in a Turkish population: a cone-beam computed tomographic analysis
ConclusionsIt is important to evaluate the parameters such as mandibular buccal and lingual bone thickness, location of the MC and the MF, and root size for atraumatic endodontic surgical approach. Evaluation of these data before endodontic surgery provides guidance to the clinician in the planning of endodontic surgery.Clinical relevanceThe mandibular posterior region, which is difficult to reach with traditional surgical approach, is now easily reached using an operation microscope. For this reason, endodontic surgical procedures have become popular in mandibular posterior teeth. Therefore, the relationship between the m...
Source: Clinical Oral Investigations - February 2, 2019 Category: Dentistry Source Type: research

Impact of type of tooth on outcome of non-surgical root canal treatment
AbstractObjectivesWe assessed the impact of type of tooth on the outcome of root canal treatment (RCT) according to factors potentially weakening the prognosis such as preoperative apical periodontitis (AP) and treatment modality (primary or secondary RCT).Materials and methodsWe scrutinized patient documents including pre- and postoperative radiographs of 640 permanent teeth receiving non-surgical RCT at Helsinki University Clinic in 2008 –2011. Of teeth, 44% were molars, 32% premolars, and 24% anterior teeth. Patients’ mean age was 51.5 years; 51% were male. AP was present in 60.5% of teeth preoperativel...
Source: Clinical Oral Investigations - February 2, 2019 Category: Dentistry Source Type: research

PEKK-made indirect temporary crowns and bridges: a clinical pilot study
ConclusionsPEKK-made temporary restorations offer a good and stable alternative to CoCr-made restorations. They have a high aesthetical advantage over CoCr restoration.Clinical relevanceEsthetic and price-efficient temporary crowns can be offered for the patient during periodontal therapy to improve its success, in particular by improving the oral hygiene. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

Both operator and heat treatment determine the centring ability of Reciproc ® files in vitro
ConclusionsPost-manufacturing heat treatment significantly improved shaping ability of the reciprocating file system Reciproc ®. The observed differences among operators suggest the possibility of further improvement by providing specific training for prospective users.Clinical relevanceMaintenance of root canal curvature may be improved by using post-manufacturing heat-treated instruments, but specific training should be recommended as well. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

Topical pimecrolimus versus betamethasone for oral lichen planus: a randomized clinical trial
AbstractObjectivesOral lichen plans (OLP) is a potentially malignant inflammatory mucocutaneous disease. CD133 is an investigated surface marker for cancer stem-like cells (CSCs) that may be involved in tumor initiation in head and neck carcinomas. We compared short-term clinical effectiveness of topical pimecrolimus as selective inflammatory cytokine release inhibitor with betamethasone cream for erosive/atrophic OLP and investigated the influence of this therapy on CD133 expression.Material and methodsThirty patients were randomly assigned into two equal groups to receive topical pimecrolimus (group I) or betamethasone (...
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

The effect of intraosseous local anesthesia of 4% articaine with 1:100,000 epinephrine on pulpal blood flow and pulpal anesthesia of mandibular molars and canines
AbstractObjectivesThe aim of this study was to determine the effect of intraosseous (IO) anesthesia with 4% articaine and 1:100,000 epinephrine on pulpal blood flow (PBF) and pulpal anesthesia of mandibular first molars and canines in human subjects.Materials and methodsTen healthy volunteers with intact mandibular first molar and canine were given an osteocentral technique of IO injection using the Quick Sleeper 5 system and 4% articaine with 1:100,000 epinephrine at distal site of mandibular first molar. The PBF was monitored by a laser Doppler flowmeter (LDF). Pulpal anesthesia was assessed with an electric pulp tester ...
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

Chronic stress and temporalis muscle activity in TMD patients and controls during sleep: a pilot study in females
AbstractObjectivesThe aim of this study was to assess the correlation between chronic stress and temporalis muscle activity during four nights.Material and methodsForty-four female subjects were recruited in five dental practices located in different areas of the federal state of Saarland, Germany (dental practice network in Saarland). The following inclusion criteria were used: female, aged between 18 and 65, no somatization or depression, and no pain medication, graded chronic pain status
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

In vitro evaluation by quantitative real-time PCR and culturing of the effectiveness of disinfection of multispecies biofilms in root canals by two irrigation systems
AbstractObjectivesThe purpose of this in vitro study was by using quantitative real-time PCR and culturing to determine the effectiveness of two irrigation and cleaning systems in removing multispecies oral biofilms from root canals.Material and methodsTwenty extracted human molars were instrumented to size #15/.02 and then cleaned with the GentleWave (GW) System. The teeth were autoclaved to provide the same sterile baseline. The molars were filled with mixed plaque suspended in BHI and centrifuged to inoculate the biofilms. After 2  weeks of incubation, the teeth were randomly divided into two treatment groups. In G...
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

Structural and histological differences between connective tissue grafts harvested from the lateral palatal mucosa or from the tuberosity area
ConclusionTuberosity grafts had a greater percentage of lamina propria and lower percentage of submucosa. The collagen content in the lamina propria was similar for both groups while the immuno-histochemical profile showed differences in the antibody expression of the epithelial cells.Clinical relevanceTuberosity grafts had more lamina propria and less submocusa, which may be beneficial for volume augmentation. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

2-Methacryloyloxyethyl phosphorylcholine (MPC)-polymer suppresses an increase of oral bacteria: a single-blind, crossover clinical trial
ConclusionsWe suggest that MPC-polymer coating in the oral cavity may suppress the oral bacterial adherence.Clinical relevanceMPC-polymer can be a potent compound for the control of oral microflora to prevent oral infection. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

Relationship between erosive tooth wear and beverage consumption among a group of schoolchildren in Mexico City
ConclusionThe intake of milk and milk-based products could be a dietary means of helping prevent ETW, especially if their consumption could replace sweet carbonated drink consumption.Clinical relevanceKnowing the impact of beverage consumption on ETW helps to provide suitable recommendations for the prevention and control of ETW in order to promote tooth longevity. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 26, 2019 Category: Dentistry Source Type: research

Deep sequencing reveals specific bacterial signatures in the subgingival microbiota of healthy subjects
ConclusionsThe present results clarify the lack of effect of tooth location in the healthy subgingival microbiota. Results may suggest that any subgingival site can demonstrate similar subject-specific microbiota.Clinical relevanceThis investigation offers a better understanding of the uniqueness of the oral microbiome. The present study will facilitate sampling in future subgingival microbiological studies. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 24, 2019 Category: Dentistry Source Type: research

Predictive value of FHIT, p27, and pERK1/ERK2 in salivary gland carcinomas: a retrospective study
AbstractObjectivesThe aim of this study was to investigate the predictive value of the biomarkers FHIT, p27, and pERK1/ERK2 in salivary gland carcinomas.Material and methodsImmunohistochemical staining of FHIT, p27, and pERK1/ERK2 of 265 patients with salivary gland carcinomas was conducted, and associations with clinico-histopathological data, overall survival, and disease-specific survival were examined.ResultsExpression of FHIT (quick score 98.7 vs. 206.4) and p27 (QS 187.3 vs. 244.8) was significantly lower in carcinomas compared to non-tumor control tissue. Loss of FHIT frequently occurred in ACC (55.2%), SDC (68.2%),...
Source: Clinical Oral Investigations - January 23, 2019 Category: Dentistry Source Type: research

Fludroxycortide cream as an alternative therapy for actinic cheilitis
ConclusionsConventional treatment with LS was effective in the remission of some AC lesions, but treatment responses were improved when associated with Fludroxycortide, especially in the more severe cases.Clinical relevanceAs it is a non-invasive therapy leading, in most cases, to adequate clinical results, safety, and tolerability, Fludroxycortide can be considered an effective alternative treatment for AC. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 23, 2019 Category: Dentistry Source Type: research

Following in the footsteps of Hippocrates —interrelation between the incidence of odontogenic abscess and meteorological parameters
ConclusionThis study supports a relationship between the incidence of odontogenic abscess and outdoor temperature, but not atmospheric pressure. A significantly higher frequency of patients with an OA presented at our emergency department on days with (comparably) low and high outdoor temperatures. Furthermore, a significant correlation between incidence and maximum temperature 2  days before presentation was found.Clinical relevanceThe treatment of odontogenic infections has become a significant economic burden to public health care facilities. The results of this study may help to adapt the numbers of doctors/dentis...
Source: Clinical Oral Investigations - January 23, 2019 Category: Dentistry Source Type: research

N-acetyl cysteine versus chlorhexidine mouthwashes in prevention and treatment of experimental gingivitis: a randomized, triple-blind, placebo-controlled clinical trial
Conclusions1.25% NAC is marginally effective in prevention and treatment of experimental gingivitis.Clinical relevanceWhen compared with the placebo, NAC showed promising preventive and treatment effects of gingivitis that deserve further development and studies.Trial registrationISRCTN31352091. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 23, 2019 Category: Dentistry Source Type: research

A novel histopathological scoring system for patients with oral squamous cell carcinoma
AbstractObjectivesTumor invasion into blood and/or lymphatic vessels, perineural invasion, and histopathological grading are evaluated to assess the biological aggressiveness of oral squamous cell carcinoma (OSCC). We aim to assess the prognostic impact of a novel scoring system, based upon the aforementioned histological parameters.Materials and methodsRetrospective chart review of 334 patients with treatment-naive squamous cell carcinoma of the oral cavity. Statistical analysis was performed using univariate and multivariate analysis. Histological grade G1 or G2 were assigned 0 points and G3 or G4 1 point. Invasion of th...
Source: Clinical Oral Investigations - January 23, 2019 Category: Dentistry Source Type: research

Changes in proinflammatory gene expression in human whole blood after contact with UV-conditioned implant surfaces
ConclusionsDifferences in the gene expression of proinflammatory cytokines after insertion of UV-conditioned titanium implants can be assessed using a human whole blood test. UV-conditioned implant surfaces apparently suppress the release ofIL1B in vitro.Clinical relevanceThe results of our publication demonstrate that modulation of the early inflammatory response in human whole blood is possible by surface treatment with UV light. In particular, the suppression ofIL1B expression, especially after the initial contact of blood cells, may be beneficial in the osseointegration of titanium implants by positively influence the ...
Source: Clinical Oral Investigations - January 21, 2019 Category: Dentistry Source Type: research

Atraumatic restorative treatment —ART in early childhood caries in babies: 4 years of randomized clinical trial
ConclusionART was effective in handling ECC, with an excellent clinical performance of ART restorations, for both GICs, during the 4  years of follow-up.Clinical relevanceART, with both GIC studied, is an alternative therapy for ECC. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 21, 2019 Category: Dentistry Source Type: research

Three dimensional maxillary growth modeling in newborns
ConclusionsThese findings indicated this method could be used for objective clinical evaluation of maxillary growth.Clinical relevanceThe resulting growth models can be used for growth studies in healthy newborns and for growth and treatment outcome studies in children with cleft lip and palate or other craniofacial anomalies. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 11, 2019 Category: Dentistry Source Type: research

Correction to: Influence of foraminal enlargement on the healing of periapical lesions in rat molars
Figures 2 and 3 in the published version of this article contained a mistake. CCP and DCP should have been FEG and NFEG. Correct figures are presented here. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 11, 2019 Category: Dentistry Source Type: research

Is the dentifrice containing calcium silicate, sodium phosphate, and fluoride able to protect enamel against chemical mechanical wear? An in situ / ex vivo study
AbstractObjectivesThe aim of this study was to investigate the effect of a dentifrice that contains calcium silicate, sodium phosphate, and fluoride on erosive-abrasive enamel wear.Material and MethodsThis randomized, single-blind in situ/ex vivo study was conducted with four crossover phases of 5  days (one group tested per phase). Bovine enamel blocks (n = 256) were allocated to 16 volunteers and 8 groups. The groups under study were test dentifrice, with calcium silicate, sodium phosphate, and 1450 ppm sodium monofluorophosphate; tin dentifrice, with 3500 ppm stannous chloride, 700 ppm ...
Source: Clinical Oral Investigations - January 8, 2019 Category: Dentistry Source Type: research

Association between perioperative oral care and postoperative pneumonia after cancer resection: conventional versus high-dimensional propensity score matching analysis
ConclusionsThere was no significant difference in postoperative pneumonia or procedure-related complications between patients with and without perioperative oral care.Clinical relevanceWhile maintaining optimal oral care in cancer patients is an important goal, the present study revealed no significant difference in postoperative outcomes. Further investigations would be needed to determine the effect of perioperative oral care. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 8, 2019 Category: Dentistry Source Type: research

Perceived helpfulness of treatments for myofascial TMD as a function of comorbid widespread pain
ConclusionsOral appliances were as likely to be reported by FM comorbid as FM − women. Oral appliances did not outperform self-management treatments on self-reported improvement of facial pain.Clinical relevanceResults support the use of self-management as first-line treatment for mTMD and potential utility of inquiring about widespread pain for treatment planning. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 8, 2019 Category: Dentistry Source Type: research

The role of immediate versus secondary removal of the odontogenic focus in treatment of deep head and neck space infections. A retrospective analysis of 248 patients
ConclusionSimultaneous removal of infection focus and abscess incision leads to the lowest LOS. If tooth extraction is performed after incision, subsequent focus extraction performed in a second stay shows lower overall-LOS than extraction at the same stay at later stage.Clinical relevanceMultiple factors tend to increase the LOS of patients with severe head and neck infections of odontogenic origin. Our data reveals the role of removal of odontogenic focus and additionally ranks further parameters that influence the LOS. Based on our findings, decisions regarding the surgical treatment can be recommended. (Source: Clinica...
Source: Clinical Oral Investigations - January 8, 2019 Category: Dentistry Source Type: research

Histologic analyses of flapless ridge preservation in sockets with buccal dehiscence defects using two alloplastic bone graft substitutes
AbstractObjectivesTo investigate whether one of two synthetic bone substitute materials used for ridge preservation in the extraction sockets with buccal dehiscence defects was superior regarding new bone formation and ridge preservation and to compare it to sites left for spontaneous healing.Materials and methodsIn sixteen dogs, P3 and P4 were hemi-sectioned and the respective distal roots were extracted. Following the preparation of a mucoperiosteal flap without vertical releasing incisions, 50% of the buccal bone was carefully removed. The extraction sites were randomly assigned either to a ridge preservation procedure ...
Source: Clinical Oral Investigations - January 8, 2019 Category: Dentistry Source Type: research

Sinus augmentation analysis of the gradient of graft consolidation: a split-mouth histomorphometric study
ConclusionOur results support the concept that osteogenesis initiates in regions proximal to the bony walls of the maxillary sinus and may be enhanced by them.Clinical relevanceThe nature of the grafting material had a greater influence on the degree of NB formation in regions distant from the native walls where there is reduced inherent osteogenic potential. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 7, 2019 Category: Dentistry Source Type: research

Comparison of the hospitalization period after microvascular reconstruction flap in trismus patients: free anterolateral thigh flap versus free forearm flap
ConclusionsThe ALT flap is more effective than the RFFF flap to reduce the length of hospitalization in trismus patients.Clinical relevanceThe ALT flap should be considered as a first-line technique in OSCC reconstruction in trismus patient reconstruction. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 7, 2019 Category: Dentistry Source Type: research

Clinical investigation of gustatory and neurosensory alterations following mandibular third molar surgery: an observational prospective study
This study aimed to prospectively observe gustatory and neurosensory alterations following surgical removal of mandibular third molars.Material and methodsA prospective clinical study was conducted with patients who required mandibular third molar extraction, recruited from the Division of Oral and Maxillofacial Surgery at the Federal University of Cear á (Brazil). Age, sex, and radiographic signs were recorded. The outcome variables were the presence or absence of gustatory and neurosensory alterations. The patients were observed preoperatively and at 7, 30, 90, and 180 days postoperatively by using gustatory ...
Source: Clinical Oral Investigations - January 6, 2019 Category: Dentistry Source Type: research

Randomized clinical trial of class II restoration in permanent teeth comparing ART with composite resin after 12  months
ConclusionNo differences in the success rates of class II restorations of ART compared to resin composite, in permanent teeth, were observed after 12  months.Clinic significantHVGIC can safely be used to restore proximal cavities in permanent teeth up to 12  months. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 6, 2019 Category: Dentistry Source Type: research

Letter to the Editor replying to Armen Nersesyan about the article published in Clinical Oral Investigations tilted “Smoking increases the frequency of micronuclei in the oral mucosa of adults relative to non-smokers—a systematic review and meta-analysis”
(Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 6, 2019 Category: Dentistry Source Type: research

Re: Does smoking habit increase the micronuclei frequency in the oral mucosa of adults compared to non-smokers? A systematic review and meta-analysis. de Geus et al., Clin Oral Investig. 2018 Jan; 22(1):81 –91
(Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 5, 2019 Category: Dentistry Source Type: research

Is there a relationship of negative oral health beliefs with dental fear and anxiety regarding diverse dental patient groups? A systematic review and meta-analysis
AbstractObjectivesThis systematic review and meta-analysis aimed to critically appraise the evidence on the relationship of oral health beliefs with dental fear and anxiety in distinct patient groups.Materials and methodsObservational studies were retrieved by Cochrane, Embase Search, Portal BVS, Clinical Trials, Ovid, Open Gray, PubMed, Scopus, and Web of Science, and they were manually checked for the inclusion of additional articles of interest. The assessment of quality of studies was performed by the application of three different versions of the Newcastle-Ottawa Scale, for cohort, case-control, and cross-sectional st...
Source: Clinical Oral Investigations - January 5, 2019 Category: Dentistry Source Type: research

Genotoxic effects in oral mucosal cells caused by the use of orthodontic fixed appliances in patients after short and long periods of treatment
This study aimed to evaluate the genotoxic effects in the oral epithelial cells of patients undergoing fixed orthodontic treatment and to compare these to a control group without treatment. The null hypothesis to be tested is that corrective orthodontic treatment at different periods does not cause genotoxic effects in patients.Material and methodsAn observational cross-sectional study including 74 patients enrolled in corrective orthodontic treatment and 21 control patients, between 11 and 35  years of age, of both genders, participated in the research. Patients undergoing treatment were divided into four treatment g...
Source: Clinical Oral Investigations - January 5, 2019 Category: Dentistry Source Type: research

Accuracy of tactile assessment in order to detect proximal cavitation of caries lesions in vitro
AbstractObjectivesDiscriminating non-cavitated from cavitated proximal lesions without tooth separation is only limitedly possible using visual-radiographic assessment alone. We evaluated how additional tactile assessment might increase the accuracy of this discrimination in vitro.MethodsSurface integrity of 46 primary molars with proximal lesions extending radiographically into outer third of dentin (ICDAS-codes: 2n = 34, 3n = 8 and 5n = 4) were mounted in groups of two in manikin heads and independently assessed by three examiners using visual-radiographic and additional tactile ...
Source: Clinical Oral Investigations - January 5, 2019 Category: Dentistry Source Type: research

How far do calcium release measurements properly reflect its multiple roles in dental tissue mineralization?
(Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 5, 2019 Category: Dentistry Source Type: research

Correction to: Influence of surface treatment on osseointegration of dental implants: histological, histomorphometric and radiological analysis in vivo
Dear Professor Dr. Matthias Hannig. Editor-in-Chief Clinical Oral Investigations. Following the publication of our paper by Calvo Guirado et al, 2015 [1] in Clinical Oral Investigations, it came to light that a certain part of the text at the materials and methods and results sections were similar. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 4, 2019 Category: Dentistry Source Type: research

Smartphone-assisted monitoring of masticatory muscle activity in freely moving individuals
AbstractObjectivesTo test a smartphone-assisted wireless device for assessing electromyographic (EMG) activity of the masseter muscle in freely moving individuals undertaking routine activities.Materials and MethodsEMG activity was detected unilaterally from the masseter muscle in 12 volunteers using surface electrodes connected to both a smartphone-assisted wireless EMG device and a fixed-wired EMG equipment (reference standard). After performing a series of standardized tasks in the laboratory, participants wore the wireless device for 8  h while performing their normal routine.ResultsThe wireless device reliably de...
Source: Clinical Oral Investigations - January 4, 2019 Category: Dentistry Source Type: research