Patients with oral lichen planus display lower levels of salivary acidic glycoproteins than individuals without oral mucosal disease
ConclusionsPatients with OLP showed a high prevalence of xerostomia and lower levels of salivary acidic type glycoproteins compared to the individuals without oral mucosa disease.Clinical relevanceIt is relevant to investigate the role of acidic glycoproteins in the pathogenesis of OLP. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 20, 2023 Category: Dentistry Source Type: research

Degradation products of resin-based materials detected in saliva in vivo
ConclusionsExposure to residual monomers and degradation products occurs in the first hours after restoration. Monomers are present in saliva shortly after restoration, but degradation products can be detected weeks after the restoration confirming a long-term release.Clinical significanceFuture research should focus more on the release of degradation products from monomers and additives from resin-based materials given their prolonged presence in saliva after restoration. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 5, 2023 Category: Dentistry Source Type: research

Clinical efficacy of endodontic protocols on reducing cultivable bacteria and endotoxin in infected root canal in patients submitted to head and neck radiotherapy: a randomised clinical trial
ConclusionsBiomechanical preparation using a reciprocating system and 2.5% NaOCl in irradiated teeth, followed by the irrigation protocol (APP or PUA), demonstrated efficacy in reducing endodontic contaminants. Ca(OH)2 as intracanal medication should be performed in irradiated patients with infected root canals.Clinical relevanceThis clinical study demonstrated that endodontic treatment in irradiated patients is efficacious at reducing bacterial load and endotoxin levels. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 1, 2023 Category: Dentistry Source Type: research

Influence of bioceramic cones on the quality of root canal filling relative to bond strength and adaptation of the adhesive interface
ConclusionThe bond between sealers and bioceramic gutta percha cones showed higher bond strength values and greater penetration into the dentin tubules.Clinical relevanceThe filling the root canal system with bioceramic sealers should be associated with bioceramic gutta percha cones. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 30, 2023 Category: Dentistry Source Type: research

Frequency and severity of malocclusions in patients with statutory health insurance in a German orthodontic practice in North Rhine Westphalia – a multi-part cross-sectional study over a 20-year period
ConclusionThe distribution of the 6 most frequent and the 5 least frequent KIG classifications was constant over a 20-year-period. Among all possible tooth and jaw misalignment variants, the sagittal classifications"D" and"M" represent the most frequent malocclusions.Clinical relevanceThe results and their comparison with historical data show that both frequency and severity of tooth and jaw misalignment with orthodontic treatment need appear identical for patients with statutory health insurance over a 20-year period. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 29, 2023 Category: Dentistry Source Type: research

Clinical efficacy of Vestibular Incision Subperiosteal Tunnel Access (VISTA) for treatment of multiple gingival recession defects: a systematic review, meta-analysis and meta-regression
ConclusionsThe VISTA technique, particularly with acellular dermal matrix (ADM) or connective tissue graft (CTG) materials, offers superior outcomes compared to the tunneling technique. The capacity of platelet-rich fibrin (PRF) to substitute for connective tissue graft (CTG) in VISTA-root coverage was noteworthy, provided there is adequate keratinized tissue width.Clinical relevanceVISTA in concert with acellular dermal matrix or CTG resulted in improved root coverage, surpassing the outcomes achieved through tunneling. PRF emerged as a viable alternative to CTG, when used in conjunction with VISTA, demonstrating comparab...
Source: Clinical Oral Investigations - November 27, 2023 Category: Dentistry Source Type: research

Impact of two different patient decision aids in prosthodontic consultations: a prospective randomized controlled study
ConclusionsWithin the limitations of this study, the use of a software-based PDA, in particular, can be recommended based on patient satisfaction and was associated with the shortest sessions for consultation.Clinical relevancePatients are routinely faced with a wealth of information in dental offices and may be overwhelmed especially by prosthetic treatment options and decision requirements. Our findings shed some light on the nature of aids that may truly be helpful in the process of shared decision-making.Trial registrationClinicalTrials.gov.Identifier: ISRCTN11472465. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 27, 2023 Category: Dentistry Source Type: research

Behavioral and metabolic risk factors associated with periodontitis in Brazil, 1990 –2019: a multidimensional analysis for the Global Burden of Disease Study 2019
ConclusionsPeriodontitis has increased in Brazil since 2005, despite the smoking reduction. Sugar-sweetened beverage was the behavioral risk that mostly accompanied the periodontal trend.Clinical relevanceOur results support upstream strategies targeting commercial, social, political, and structural determinants to tackle NCDs and reduce oral health inequities. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 27, 2023 Category: Dentistry Source Type: research

Comparative evaluation of effect of nisin-incorporated ethylenediamine tetraacetic acid and MTAD on endodontic biofilm eradication, smear layer removal, and depth of sealer penetration
ConclusionN-EDTA had negligible cytotoxicity with similar smear layer removal ability, sealer penetration, and better antibiofilm potential than MTAD.Clinical relevanceN-EDTA can serve as a viable alternative endodontic irrigant. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 24, 2023 Category: Dentistry Source Type: research

CO2 laser irradiation combined with fluoridated dentifrice improved its protective effect on caries lesion progression regardless of the acidulated phosphate fluoride gel application: An in situ study
ConclusionAlthough APF promotes the high formation of CaF2 and FAp, the combined use of FD with CO2 laser overcomes the APF effect in inhibiting the progression of artificial caries-like lesions in situ.Clinical significanceUnder the in situ design of this study, remineralization of white spot lesions was achieved through CO2 laser irradiation and daily use of fluoridated dentifrice. Future clinical trials are encouraged to substantiate this finding. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 24, 2023 Category: Dentistry Source Type: research

Convex triangular vs. cylindrical field of view: how does the shape of the FOV affect radiation dose?
ConclusionConvex triangular fields of view delivered slightly lower effective doses than the cylindrical fields of view of similar dimensions in the R100 and X800 CBCT devices.Clinical relevanceUnderstanding the influence of the image geometry formation in effective dose allows optimization to reduce patient dose. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 23, 2023 Category: Dentistry Source Type: research

Effect of glass –ceramic coating versus alumina air-abrasion on the bond strength and residual stress of zirconia
ConclusionsThe DCMhotbond glass –ceramic coated zirconia showed comparable bond strength to the alumina air-abrasion technique.Clinical RelevanceThe DCMhotbond glass –ceramic coating technique is a promising alternative for zirconia surface pre-treatment. However, further investigations are needed before suggesting its clinical use. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 22, 2023 Category: Dentistry Source Type: research

Keratinized tissue augmentation using collagen-based soft tissue substitute with/without epidermal growth factor on buccally positioned implants: a pilot preclinical study
ConclusionAll groups presented increased KT zone, but FGG treatment was more favored. The addition of EGF to CM appeared not to enhance KT formation.Clinical relevanceFGG treatment was more favorable to re-establish the KT zone than other treatment modalities. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 22, 2023 Category: Dentistry Source Type: research

Studying positional changes of the disc-condyle-fossa complex in ADDWoR patients after TMJ disc repositioning surgery
ConclusionsADDWoR leads to forward and downward displacement of the disc relative to the condyle and upward displacement of the condyle relative to the tuberosity. DR surgery improved upon the structural abnormalities of the TMJ complex, for which stability was maintained as determined in the 9 to 12 month postoperative follow-up.Clinic relevanceDR surgery effectively and constantly improves the positional abnormalities of the TMJ complex. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 21, 2023 Category: Dentistry Source Type: research

Intraoral medical devices for sustained drug delivery
ConclusionWe anticipate that with the development of 3D printing and new polymers, the technology of flexible and comfortable devices for prolonged drug delivery in the oral cavity will develop intensively.Clinical relevanceThe presented review is therefore a useful summary of the current technological state, when in fact none of the existing devices has been widely accepted clinically. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - November 20, 2023 Category: Dentistry Source Type: research