Evaluation of advanced platelet-rich fibrin compared to subepithelial connective tissue graft in the surgical management of interdental papilla recession: a randomized controlled trial
ConclusionBoth CTG and A-PRF were found to be equally effective in increasing deficient IDP height with Han and Takei ’s surgical technique, with no significant difference. Within the current study’s limitations, A-PRF seems to be a viable alternative to CTG in the treatment of GBTs.Clinical relevanceMultilayered A-PRF membrane can be used as a choice in the augmentation of receded papillae, using Han and Takei ’s technique. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 11, 2024 Category: Dentistry Source Type: research
Effect of simvastatin topical use on alveolar bone after tooth extraction: a scoping review
ConclusionsIntra-alveolar simvastatin post-tooth extraction has been to be shown to be effective and safe for preserving alveolar bone, with varied concentrations and carriers, with no significant adverse effects.Clinical relevanceThis review provides critical insights into the effects of simvastatin on alveolar bone regeneration, informing potential benefits and possible challenges associated with its post-extraction application.OSF Registry protocolosf.io/q3bnf (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 10, 2024 Category: Dentistry Source Type: research
The effects of injectable platelet-rich fibrin application on wound healing following gingivectomy and gingivoplasty operations: single-blind, randomized controlled, prospective clinical study
ConclusionsI-PRF applications revealed positive effects on epithelial wound healing after gingivectomy and gingivoplasty operations.Clinical relevancePlatelet concentrates such as I-PRF accelerate wound healing and contribute to the patient ’s comfort and quality of life. I-PRF application may have positive effects on wound healing after gingivectomy and gingivoplasty operations. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 10, 2024 Category: Dentistry Source Type: research
No increased risk of osteonecrosis of the jaw in osteoporotic patients with dental implants: a nationwide cohort study
ConclusionsThe results may suggest that dental implants are not associated with an increased risk of ONJ. A further study on whether dental implants are associated with lower ONJ risk is needed.Clinical relevanceDental implants did not increase the risk of ONJ development in osteoporotic patients, even with a history of bisphosphonates. This may suggest that the risk profiles for ONJ occurrence between selective insertion of dental implants and other dentoalveolar surgery associated with infectious conditions are different. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 9, 2024 Category: Dentistry Source Type: research
East Asian and Southern European craniofacial class III phenotype: two sides of the same coin?
ConclusionsA distinct distribution of Spanish and South Korean participants was observed in the global analysis. Interethnic and interethnic differences were observed, primarily in the cranial base and maxilla size, mandible projection, and craniofacial pattern.Clinical relevanceAccurate phenotyping, reflecting the complexity of skeletal class III phenotype across diverse populations, is critical for improving diagnostic predictability and future personalised treatment protocols. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 9, 2024 Category: Dentistry Source Type: research
Can delta neutrophil index values predict the success of periodontal treatment in patients with periodontitis?
ConclusionConsistent with previous findings in the literature, the patients with periodontitis were determined to have higher levels of DNI, CRP, neutrophils, and WBC, compared to the individuals without periodontitis. Although a decrease was seen in DNI after NSPT, this was not at a significant level.Clinical relevanceDNI is a guide in the evaluation of inflammation at the onset of periodontal disease, but studies with a larger number of cases are needed to use these parameters in the evaluation of treatment success.Trial registrationThis study was retrospectively registered on December 27, 2022, with the number NCT056666...
Source: Clinical Oral Investigations - January 9, 2024 Category: Dentistry Source Type: research
Effect of two irrigating solutions on antimicrobial activity and clinical and radiographic success after endodontic treatment in primary teeth: a randomized clinical trial
ConclusionsOne percent NaOCl and 2% CHX were effective for clinical and radiographic success and antimicrobial activity in primary teeth submitted to pulpectomy.Clinical relevanceStudying the antimicrobial activity and clinical and radiographic outcomes of pulpectomy in primary teeth using NaOCl and CHX as irrigants is clinically relevant because it provides information for optimizing treatment protocols and improving the quality of care for pediatric patients. It contributes to evidence-based practice and can potentially lead to better outcomes, reduced complications, and enhanced patient experiences. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 8, 2024 Category: Dentistry Source Type: research
Effect of adjuvant probiotic therapy (Lactobacillus reuteri) in the treatment of periodontitis associated with diabetes mellitus: clinical, controlled, and randomized study
ConclusionSubgingival instrumentation improved the clinical periodontal parameters in patients with T2DM. The use ofL. reuteri probiotics had no additional effects compared with the placebo; however, there was a positive effect on the lipoprotein subfraction.Clinical relevanceScientific rationale for study: subgingival instrumentation with probiotics may be a proposal for the treatment of periodontitis (P), especially for patients with type 2 diabetes mellitus (T2DM). Principal findings: the use ofL. reuteri probiotics had no additional effects compared with the placebo; however, there was a positive effect on the lipoprot...
Source: Clinical Oral Investigations - January 6, 2024 Category: Dentistry Source Type: research
Analysis of ultra-short implants with different angulations: a retrospective case –control study with 2 to 9 years of follow-up
ConclusionsPBL, success and survival rates of axial ultrashort implants and tilted ultrashort implants are comparable to those of conventional implants.Clinical relevanceThis retrospective study revealed that ultrashort implants, even when placed with an angulation > 17°, can safely be used to support partial fixed prostheses. Further prospective clinical studies with larger samples and prospective design are needed to confirm these findings. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 6, 2024 Category: Dentistry Source Type: research
Comparative effectiveness of types of denture adhesives in enhancing retention and function of complete dentures: a systematic review with network meta-analysis
ConclusionsCream and powder denture adhesives are effective in enhancing the retention of mandibular dentures (Kapur ’s index) and bite force in the premolar/molar region in complete denture wearers (moderate level of certainty of evidence).Clinical relevanceCream and powder denture adhesives are effective in improving the retention and function of complete dentures. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 6, 2024 Category: Dentistry Source Type: research
Hyperbaric oxygen therapy as an adjunct treatment of periodontitis, MRONJ, and ONJ: a systematic literature review
ConclusionsHBO has shown superior efficacy compared to antibiotics as a prophylactic measure in preventing osteoradionecrosis (ORN) in patients with a history of high mandibular irradiation. Clinicians should consider referring such patients for HBO therapy before and after tooth extractions. However, for the surgical excision of existing ORN lesions, HBO therapy does not yield significant benefits but does not negatively impact outcomes either. Regarding the treatment of periodontitis patients, the variability among studies prevents definitive conclusions. HBO therapy as an adjunct to SRP in periodontitis treatment produc...
Source: Clinical Oral Investigations - January 5, 2024 Category: Dentistry Source Type: research
Dental and periodontal dimensions stability after esthetic clinical crown lengthening surgery: a 12 ‐month clinical study
ConclusionsACL procedure was effective. Although some rebound occurred, that was not clinically important. PD tended to reestablish its original length, partially due to a migration of GM during the healing period. Besides, a thickening of supracrestal soft tissues was observed.Clinical relevanceThe present study centers on the factors influencing the stability of periodontal tissues after esthetic crown lengthening, underscoring the procedure ’s influence on esthetics and biology and the need for careful treatment planning. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 5, 2024 Category: Dentistry Source Type: research
Optical clearing agents based on metallic and dielectric nanoparticles for caries diagnostic by optical coherence tomography
This study aimed to assess the effect of titanium dioxide (TiO2) and silver (Ag) nanoparticles dispersed in glycerol or water, serving as optical clearing agents nanocolloids (OCAs-NC), for improving optical coherence tomography (OCT) images and highlighting incipient lesions in ex vivo human teeth.Materials and methodsTwelve human teeth with incipient lesions were divided into seven groups according to the OCA-NC; they were subjected to G1 (air), G2 (glycerol), G3 (TiO2 0.1%), G4 (TiO2 0.01%), G5 (TiO2 0.001%), G6 (AgNO3 10%), and G7 (AgNO3 100%). The OCA-NC was applied to the occlusal surface, and two-dimensional images ...
Source: Clinical Oral Investigations - January 4, 2024 Category: Dentistry Source Type: research
Saliva biofilm-derived outer membrane vesicles regulate biofilm formation and immune response of oral epithelial cells on titanium surfaces
ConclusionHealthy saliva biofilm derived OMVs regulate the activity and pathogen composition of biofilms formed on titanium, while modulating the secretion of pro-inflammation factors of oral epithelial cells grown on titanium surfaces.Clinical relevanceHealthy saliva biofilm OMVs may regulate the early biofilm formation on abutment surfaces and modulate epithelial cell immune response, which may alter the peri-implant niche and participate in the pathogenesis of peri-implant disease. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 4, 2024 Category: Dentistry Source Type: research
Evaluation of the impact of orthodontists ’ smile with malocclusions on social media and professional credibility
ConclusionOrthodontists with an IOTN grade 1 rating were perceived as more competent, reliable, and professional, thus making it more likely for laypeople to choose them as their preferred providers.Clinical relevanceThe smiles of professionals play a significant role in laypeople ’s decision to choose them as their orthodontist, and strategic utilization of social media can effectively deliver health information to a larger audience in a faster and more direct manner. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 4, 2024 Category: Dentistry Source Type: research
