Morphometric micro-CT study of contralateral mandibular incisors
ConclusionsThe findings of this study further establish the significant similarities between contralateral mandibular incisors, reinforcing their suitability as a reliable substrate for root canal comparison studies.Clinical relevanceThe absence of statistically significant differences between contralateral pairs in normalized parameters underscores their potential as a reliable reference point for root canal comparison studies in clinical dentistry. Furthermore, our findings emphasize the importance of individualized treatment planning, considering the natural symmetry in mandibular incisors to enhance clinical decision-m...
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

The impact of COVID-19 pandemic in patients with a diagnosis of Oral Lichen Planus: Pain perception and psychological profile analysis
ConclusionsThese findings highlight the potential interplay between psychological stress and oral health conditions, emphasizing the need for a comprehensive understanding of OLP's complex etiology and its response to external stressors.Clinical relevanceMultidisciplinary care strategies to address both physical and psychological aspects of OLP patients is recommended following the present findings. Further research is warranted to confirm these observations in larger multicenter studies and to guide tailored guidance approaches for OLP patients during challenging times. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

Dental caries prevalence and severity positively associate with AMY1 gene copy number
ConclusionTC and CS were positively related to the AMY1GCN.Clinical relevanceDental caries has a high prevalence and a multifactorial etiology and has been related to a genetic component. Indeed, the salivary enzyme alpha-amylase could play a significant role in caries susceptibility, considering that its codifying gene (AMY1) can show variation in its gene copy number. This can be considered an important factor for the development of caries at a genetic level. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

Modified submandibular mandibulotomy approach versus lip-splitting approach in tongue cancer surgery: a retrospective paired-cohort study
ConclusionThe MSMM approach without lip-splitting achieves similar tumor control, better aesthetic results, and QOL compared to LSM approach. It is a safe and effective surgical approach for patients with TSCC.Clinical relevanceThe MSMM approach without lip-splitting is oncological safety in tongue cancer surgery and is scrutinized as one part of the treatment concept for better aesthetic results. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

The association of aldehyde exposure with the risk of periodontitis: NHANES 2013 –2014
ConclusionsIsopentanaldehyde and propanaldehyde are positively associated with the risk of periodontitis.Clinical relevancePeriodontitis may be associated with exposure to mixed aldehyde. This study emphasizes the important role of aldehydes in primary prevention of periodontitis. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

The influence of truncated-conical implant length on primary stability in maxillary and mandibular regions: an in vitro study using polyurethane blocks
ConclusionsThese results demonstrated that the implant ’s length mainly influences the IT and RT values in the polyurethane blocks that mimic the mandibular region of the bone, resulting in higher values for the 3p S implants, while the RFA values remained unaffected. However, in the lowest density block simulating the maxillary bone, 3p L implants ex hibited significantly higher ISQ values.Clinical relevanceTherefore, our data offer valuable insights into the biomechanical behavior of these implants, which could be clinically beneficial for enhancing surgical planning. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

Systematic review and meta-analysis of randomized controlled trials evaluating the efficacy of non-surgical periodontal treatment in patients with concurrent systemic conditions
ConclusionCompared to the untreated controls, NSPT notably reduced mean PD, mean CAL, and %BOP while increasing %PD  ≤ 3 mm in patients with concurrent systemic conditions. These findings suggest that NSPT is also an effective procedure in managing periodontitis in patients with concurrent systemic conditions.Trial registrationThis systematic review was registered under the protocol registration number CRD42021241517/PROSPERO. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

Encapsulation of a novel peptide derived from histatin-1 in liposomes against initial enamel caries in vitro and in vivo
ConclusionAs a safe and effective application model, DK5-Lips could significantly promote the remineralization of initial enamel caries both in vitro and in vivo.Clinical relevanceThe potential of liposome utilization as vehicle for oral delivery of functional peptides may provide a new way for enamel restoration. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

Biological evaluation of indirect restorations in endodontically treated posterior teeth with deeply located proximal margins following deep margin elevation versus surgical crown lengthening: a randomized controlled trial
ConclusionsDME and CL are considered clinically successful with favorable biologic responses.Clinical relevanceThe deep margin elevation approach could provide a more conservative solution when relocating deeply seated cervical margins in a more coronal position. DME reduced the number of visits and time needed for the restoration of endodontically treated teeth. Surgical crown lengthening remains a gold standard procedure in the re-establishment of the supracrestal tissue attachment, especially in cases where cervical margins are beyond the elevation capacity. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 26, 2023 Category: Dentistry Source Type: research

A novel approach for gingiva thickness measurements around lower anterior teeth by means of dental magnetic resonance imaging
ConclusionDental MRI successfully visualizes delicate structures like the gingiva in the anterior mandible and achieves a high correlation with superimposed CBCT scans, with clinically acceptable deviations.Clinical relevanceThe present study helps to establish dental MRI as a radiation-free alternative to conventional radiographic methods. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 23, 2023 Category: Dentistry Source Type: research

Clinical outcomes of zirconia implants: a systematic review and meta-analysis
ConclusionZirconia implants present high 10-year CSR and short-term low MBL.The review was registered in PROSPERO (CRD42022342055).Clinical relevanceThe clinical outcomes observed for zirconia dental implants are very promising, although these have not yet been extensively studied as titanium alloy implants. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 23, 2023 Category: Dentistry Source Type: research

Racial inequality in complete dental prosthesis delivered: can public services reduce inequities?
ConclusionsAlthough municipalities with a DSC, and with more OHTs offer better access to complete dental prosthesis for blacks, racial inequality still impacts the delivery of the service. Primary and secondary healthcare services may even exacerbate this.Clinical relevancePolicymakers should monitor racial inequities in healthcare services. The currently unmet needs of black people are critical, especially in cities with more OHTs and/or increased proportions of black people. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 23, 2023 Category: Dentistry Source Type: research

Optimizing the use of low-frequency ultrasound for bacterial detachment of in vivo biofilms in dental research —a methodological study
ConclusionsWith the use of low-frequency, low-intensity ultrasound, significantly higher bacterial counts and diversity can be reached. A shorter sonication time of 1 min shows the best results overall.Clinical relevanceThis standardization is recommended to study initial oral biofilms aged up to 24 h to maximize the outcome of experiments and lead to better comparability of studies. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 23, 2023 Category: Dentistry Source Type: research

Influence of crestal and sub-crestal implant position on development of peri-implant diseases: a 5-year retrospective analysis
ConclusionsWithin the limitation of the present study, the clinical and radiographic outcomes showed that the percentage of peri-implant mucositis and peri-implantitis was not statistically significant for both groups after 5  years follow-up.Clinical relevanceThe outcomes of present study clinically demonstrated that a deep position of implant shoulder did not provide any benefits. On the contrary, it may be considered a possible risk indicator for implant diseases. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 23, 2023 Category: Dentistry Source Type: research

Females with painful temporomandibular disorders present higher intracortical facilitation relative to pain-free controls
ConclusionsFemales with TMD exhibit heightened motor cortex intracortical facilitation in the hand representation, potentially indicating altered cortical excitability beyond the motor face area. This suggests a role for cortical excitability in TMD pathophysiology, influenced by psychosocial factors.Clinical relevanceUnderstanding cortical excitability in TMD may inform targeted interventions. Psychosocial variables may play a role in cortical excitability, emphasizing the multidimensional nature of TMD-related pain. Further research is needed to confirm and expand upon these findings, with potential implications for the ...
Source: Clinical Oral Investigations - December 22, 2023 Category: Dentistry Source Type: research