Diagnostic value of cone beam computed tomography for root canal morphology assessment – a micro-CT based comparison
ConclusionSensibility to detect both lateral canals and apical deltas with CBCT was low. These results attest to the fact that minor anatomical changes might be difficult to identify with CBCT imaging, hampering its diagnostic value. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 8, 2024 Category: Dentistry Source Type: research
Clinical and thermographic evaluation after lower third molar extractions and the application of different photobiomodulation protocols: double-blind randomised clinical trial
ConclusionsThe association of the 660 nm with 808 nm, and the increase in energy did not showed more benefits in pain reduction oedema, or acceleration of the closure of the soft tissues of the dental sockets of lower third molars, in the protocols used here.Clinical relevanceThere is no need to combine lasers at wavelengths of 660 and 808 nm to reduce oedema, pain and repair of soft tissues after extraction of lower third molars.Clinical trial registrationThis trial was registered in the Brazilian Registry of Clinical Trials (ReBEC) with the following code: RBR-66pyrh8, on 29th December, 2022. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 8, 2024 Category: Dentistry Source Type: research
Effects of Nd:YAG laser irradiation at different energy densities on dentin bond durability under simulated pulpal pressure
ConclusionsUnder simulated pulp pressure, Nd:YAG laser pretreatment altered the chemical composition of dentin and improved the immediate and long-term bond strength.Clinical relevanceThis study investigated the optimal parameters for Nd:YAG laser pretreatment of dentin, which has potential as a clinical method to strengthen bonding. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 8, 2024 Category: Dentistry Source Type: research
Central giant cell granuloma of the jaws —long-term clinical and radiological outcomes of surgical and pharmacological management
ConclusionsOur analysis indicates better outcomes using a combined approach, including both pharmacological and surgical treatments in large aggressive lesions. Pharmacological treatment resulted in decreased size or well-defined lesions, thus reducing the need for extensive bone resection. Dual treatment with corticosteroids and calcitonin showed no superior outcomes, but a larger cohort should be assessed.Clinical RelevanceThere are several protocols for treatment of central-giant-cell-granuloma lesions, but most are not fully established. It is important to report results that contribute to the establishment of proven p...
Source: Clinical Oral Investigations - March 7, 2024 Category: Dentistry Source Type: research
Immunologic burden links periodontitis to acute coronary syndrome: levels of CD4 + and CD8 + T cells in gingival granulation tissue
ConclusionsThe increased number of CD8 + T-lymphocytes in both group ACS + P and group no ACS + P resulted in a reduction of the CD4 + /CD8 + ratio in gingival tissue when compared with no ACS + G group.Clinical relevanceThe decrease of CD4 + /CD8 + ratio in gingival tissue reflects periodontitis and may be associated with severe adverse outcomes in people with ACS. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 7, 2024 Category: Dentistry Source Type: research
Biomechanical analysis of alveolar bones with compromised quality supporting a 4-unit implant bridge; a possible association with implant-related sequestration (IRS)
ConclusionsOcclusal force applied to poor-quality bone can result in microdamage. Given that unrepaired microdamage may initiate medication-related osteonecrosis of the jaw, long-term occlusal force on fragile bones might be a risk factor.Clinical RelevanceWhen planning implant treatment for patients with compromised bone status, clinical modifications such as strategic placement of implants and optimization of restoration morphology should be considered to reduce excessive strain which might be associated with IRS or PI-MRONJ. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 7, 2024 Category: Dentistry Source Type: research
Deep learning methods for fully automated dental age estimation on orthopantomograms
ConclusionsThe proposed automated framework enhances the dental age estimation process in a fast and standard manner, enabling the reference of any accessible population.Clinical relevanceThe tooth development staging network can facilitate the precise identification of permanent teeth with abnormal growth, improving the effectiveness and comprehensiveness of dental diagnoses using pediatric orthopantomograms. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 7, 2024 Category: Dentistry Source Type: research
Clinical outcomes of narrow- and regular-diameter implants with bone augmentation in the anterior maxilla: a systematic review and meta-analysis
ConclusionThe results indicate that NDIs yield clinical outcomes similar to those of RDIs with bone augmentation in the anterior maxilla over a 36-month follow-up period.Clinical relevanceConsidering the similar clinical outcomes, the shortened treatment duration and more rapid esthetic improvement associated with NDIs may render them preferrable to RDIs with bone augmentation, particularly in this esthetic zone. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 6, 2024 Category: Dentistry Source Type: research
Comparative bioactivity and immunomodulatory potential of the new Bioroot Flow and AH Plus Bioceramic sealer: An in vitro study on hPDLSCs
ConclusionBrF and AHPbcs exhibit adequate and comparable cytocompatibility on hPDLSCs. BrF also promoted the osteo/cementogenic differentiation of hPDLSCs. Both calcium silicate-based sealers favored the downregulation of the inflammatory cytokine IL-6 and the calcified nodule formation from hPDLSCs. BrF exerted a significantly higher influence on cell mineralization than AHPbcs.Clinical relevanceThis is the first study to elucidate the biological properties and immunomodulatory potential of Bioroot Flow and AH Plus Bioceramic Sealer. The results act as supporting evidence for their use in root canal treatment. (Source: Cl...
Source: Clinical Oral Investigations - March 5, 2024 Category: Dentistry Source Type: research
Maternal periodontitis may cause lower birth weight in children: genetic evidence from a comprehensive Mendelian randomization study on periodontitis and pregnancy
ConclusionsThis Mendelian Randomization study underscores the genetic influence of periodontitis on specific adverse pregnancy outcomes, particularly concerning labor duration and lower birth weight deliveries.Clinical relevanceOur study emphasizes the critical importance of maintaining periodontal health during pregnancy and offers genetic evidence supporting these associations. Further investigation is required to delve deeper into the specific underlying mechanisms. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 5, 2024 Category: Dentistry Source Type: research
Removal of fiber posts using conventional versus guided endodontics: a comparative study of dentin loss and complications
ConclusionsCompared to the conventional freehand technique, GE resulted in significantly less radicular dentin loss, a few deviations but no perforations.Clinical relevanceGuided endodontics can improve the speed and safety of fiber post removal without root perforation. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 4, 2024 Category: Dentistry Source Type: research
Relationships between functional temporomandibular joint space and disc morphology, position, and condylar osseous condition in patients with temporomandibular disorder
ConclusionsCondylar displacement causes joint space alterations while exerting compressive pressure on both the disc and condyle.Clinical relevanceProper condylar positioning within the fossa is recommended to ensure sufficient articular disc accommodation. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 4, 2024 Category: Dentistry Source Type: research
Evaluation of the effect of extraction in comparison to distalization on the maxillary third molars in class II malocclusion: a retrospective study
ConclusionSignificant uprighting and occlusal positioning of the maxillary third molars occurred in the premolar extraction treatment group when compared to the distalization treatment group. The results of the current study highlight the importance of recognizing maxillary third molars during orthodontic treatment planning of Class II malocclusion cases. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 4, 2024 Category: Dentistry Source Type: research
Effect of sodium hypochlorite gel on bacteria associated with periodontal disease
ConclusionMixing of the components should be made in a timeframe of 20 min before applications. An optimization of the composition of the NaOCl formulation might be possible and should be a topic in further in vitro studies.Clinical relevanceThe AA-NaOCl gel formulation can be mixed up to 20 min before application. Further, the study indicates that the composition of the NaOCl gel formulation can be optimized. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 2, 2024 Category: Dentistry Source Type: research
Machine learning-based medical imaging diagnosis in patients with temporomandibular disorders: a diagnostic test accuracy systematic review and meta-analysis
ConclusionsMost studies had high risks of bias in Patient Selection and Index Test. Some algorithms are relatively satisfactory and might be promising in intelligent diagnosis. Overall, more high-quality studies and more types of algorithms should be conducted in the future.Clinical relevanceWe evaluated the diagnostic accuracy of the existing models and provided clinicians with much advice about the selection of algorithms. This study stated the promising orientation of future research, and we believe it will promote the intelligent diagnosis of TMDs. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - March 2, 2024 Category: Dentistry Source Type: research
