Survival of dental implants and occurrence of mucosal overgrowth in patients with head and neck cancer treated with/without radiotherapy and mucosal graft —two-year follow-up
ConclusionImplant survival was not significantly influenced by radiation therapy in this observational period. In grafted bone, implant survival was significantly inferior than in native bone. Mucosal overgrowth around implants was more common in mucosal grafted areas versus nongrafted.Clinical relevanceThis study demonstrates the impact of grafted bone to dental implant survival rate and mucosal overgrowth. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 25, 2024 Category: Dentistry Source Type: research
3D analysis of condylar and mandibular remodeling one year after intra-oral ramus vertical lengthening osteotomy
ConclusionThis study confirms the overall stability obtained with IORVLO for the correction of PVI.Clinical relevanceThis study aims to precise indication of IORVLO, and to validate the clinical and anatomical stability of results. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 25, 2024 Category: Dentistry Source Type: research
Comparison of suture and sutureless techniques on postoperative complications after third molar surgery: a systematic review
ConclusionThe omission of postoperative sutures in third molar surgeries appears to favor pain and edema outcomes within the first 24 h after the procedure, as well as trismus within the same timeframe.Clinical relevance.Despite the suture being the standard conduct in tooth extractions. The omission of sutures in third molar extractions may favor inflammatory outcomes of pain, edema, and trismus in the immediate postoperative period. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 25, 2024 Category: Dentistry Source Type: research
Occult metastasis is no burden factor in oral squamous cell carcinoma patients when adhering to a standardized approach in neck dissection
ConclusionsOverall, our findings suggest that conducting a standardized approach in ND should be applied in terms of management of the neck in order to maintain survival rates and to prevent neck recurrence in OSCC patients.Clinical relevance.None of the risk factors for occult metastasis can be reliably assessed preoperatively. Although elective ND does not guarantee the complete prevention of neck recurrence, it increases the likelihood of either timely removal of micrometastases or strengthens the justification for adjuvant therapy. Consequently, this approach leads to improvements in clinical outcomes. (Source: Clinica...
Source: Clinical Oral Investigations - January 24, 2024 Category: Dentistry Source Type: research
The tongue microbiome of young patients with chronic kidney disease and their healthy mothers
ConclusionsThe tongue microbiome of the study participants showed no relevant CKD-associated differences compared to their mothers and appears to be a highly preserved niche in the oral cavity. Differences observed in the abundance of individual species in this study could be attributed to the age rather than CKD, even after a mean disease duration of 11 years.Clinical relevanceCKD and its associated metabolic changes appear to have no detectable impact on the resilient tongue microbiome observed in young patients. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 24, 2024 Category: Dentistry Source Type: research
Does malocclusion affect ingestion: a systematic review
ConclusionMalocclusion has a negative impact on ingestion function. During orthodontic consultations, particular interest should be directed towards chewing, biting, and swallowing disorders, which can affect patients ’ nutritional status. This review offers arguments for designing further studies assessing the extent to which malocclusions may affect nutritional status.Clinical relevanceOrthodontic treatment should focus on improving patients ’ ingestion. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 24, 2024 Category: Dentistry Source Type: research
Is there a difference in surgical accuracy following bimaxillary surgery between cleft and non-cleft patients?
ConclusionThe present study demonstrates that high surgical accuracy in maxillary movements can be achieved in both cleft and non-cleft patients using VSP and interocclusal splints.Clinical relevanceOrthognathic cases with cleft can be performed with 3D VSP to obtain a satisfactory surgical accuracy. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 24, 2024 Category: Dentistry Source Type: research
Gingival bleeding as a predictor of handgrip strength —an observational study and a pilot randomized clinical trial
ConclusionTaken together, our findings suggest that gingival bleeding could act as a predictor of handgrip strength and its improvement after non-surgical periodontal therapy.Clinical relevanceGingival bleeding, either as self-perceived or clinically detected, may impact handgrip strength, an important marker of muscle frailty and mortality. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 23, 2024 Category: Dentistry Source Type: research
Salivary Th17 cytokine, human β-defensin 1–3, and salivary scavenger and agglutinin levels in Crohn’s disease
ConclusionsCrohn ’s disease does not relate to salivary antimicrobial hBD 1–3 or SALSA levels. While Crohn’s disease patients have higher salivary Th17 cytokine levels in comparison to systemically healthy controls, an independent association between Crohn’s disease and Th17 cytokine profile is still missing .Clinical relevanceDiminished Th17 cytokine response in Crohn ’s disease, which might be related to genetic susceptibility, can be also visualized in saliva. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 22, 2024 Category: Dentistry Source Type: research
Genetic causal association between rheumatoid arthritis and periodontitis: a bidirectional two-sample Mendelian randomization analysis
ConclusionThis study revealed that there was a genetic causal effect of seropositive RA on PD, suggesting that this subtype of RA patients may require specific clinical attention to prevent the development of PD. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 20, 2024 Category: Dentistry Source Type: research
Molar incisor hypomineralization and oral health-related quality of life: a sample of 8 –12-years-old children
ConclusionsAmong the children with MIH, the OHRQoL was found to be negatively affected. The teeth with the MIH tend to reveal more tooth sensitivity than healthy teeth. Many conditions such as having MIH, and tooth sensitivity might have an impact on the OHRQoL. In addition, more sensitivity to the stimulus was observed in the teeth with lower tooth maturity status; the dental age and dental maturity might have effects on tooth sensitivity.Clinical relevanceConsidering the negative impacts due to MIH, the evaluation of OHRQoL is critical for dentists to employ a well-defined guide in their clinical decisions. (Source: Clin...
Source: Clinical Oral Investigations - January 20, 2024 Category: Dentistry Source Type: research
Effect of the use of bromelain associated with bioactive glass-ceramic on dentin/adhesive interface
ConclusionsBromelain associated with Biosilicate did not affect the BS to SD. In CAD, Br5%Bio decreased immediate BS but had no long-term influence. This association decreased the proteolytic activity.Clinical relevanceBromelain and Biosilicate may enhance the longevity of adhesive restorations by inhibiting endogenous proteases. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 20, 2024 Category: Dentistry Source Type: research
Clinical performance of a glass-hybrid system in comparison with a resin composite in two-surface class II restorations: a 5-year randomised multi-centre study
ConclusionsIn terms of success and survival rates, both the glass-hybrid restorative system and the nano-hybrid resin composite have been shown to perform satisfactorily.Clinical relevanceThe results of this study indicate that EQUIA Forte can be one of the therapeutic options for moderate to large two-surface class II restorations of posterior teeth. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 20, 2024 Category: Dentistry Source Type: research
Salivary metabolomics in patients with oral lichen planus: a preliminary study based on NMR spectroscopy
ConclusionsSalivary tyrosine was of particular interest and a promising finding for the screening of OLP and its progression. Further longitudinal studies are required to establish it as a reliable salivary biomarker in OLP.Clinical relevanceThe salivary metabolic profiling can describe the pathologic characteristics of OLP on non-invasive saliva samples and NMR analysis. Salivary metabolites provide details to considered early detectors and to impact oral health of OLP patients. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 18, 2024 Category: Dentistry Source Type: research
The assessment of halitosis with a new screening tool in medication-related osteonecrosis of the jaw
ConclusionsQuantifying the level of halitosis can be used to screen for MRONJ in patients taking bisphosphonates, such as patients with osteoporosis, prostate cancer, and breast cancer.Clinical RelevanceMRONJ is accompanied by bad breath, and the concentrations of hydrogen sulfide and methyl mercaptan are associated with MRONJ. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - January 17, 2024 Category: Dentistry Source Type: research
