Impact of different cephalometric skeletal configurations on anatomic midface parameters in adults
ConclusionsSkeletal configurations have an impact on parameters of the bony skull. Also, measurable adaptations of the muscular phenotype could result.Clinical relevanceThe association between viscerocranial morphology and midface anatomy might be beneficial for tailoring orthodontic appliances to individual anatomy and planning cortically anchored orthodontic appliances. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 29, 2023 Category: Dentistry Source Type: research
The regenerative potential of Tideglusib and CHIR99021 small molecules as potent odontogenic differentiation enhancers of human dental pulp stem cells
ConclusionsBoth small molecules successfully induced odontogenic differentiation of hDPSCs through Wnt/ β-catenin pathway activation.Clinical relevanceThese findings suggest that Tideglusib and CHIR99021 can be applied clinically in pulp regeneration to improve strategies for vital pulp regeneration and to promote dentine repair. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Effects of disinfection with a vinegar-hydrogen peroxide mixture on the surface characteristics of denture acrylic resins
ConclusionsThe VHP mixture was not deleterious to conventional and 3D-printed resin surfaces.Clinical relevanceConventional and 3D printed resin dentures can be disinfected with a VHP mixture in a 1:1 ratio because this mixture does not substantially affect the surface characteristics after 90 daily immersions. On the contrary, sodium hypochlorite, hydrogen peroxide, and vinegar solutions, even in low concentrations, should be used with caution for denture disinfection because they may alter the resin microtopography over time. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Efficacy of injectable platelet-rich fibrin on clinical and biochemical parameters in non-surgical periodontal treatment: a split-mouth randomized controlled trial
ConclusionsEspecially in the test group, the significant increase in VEGF and IL-10 expressions and the decrease in TNF- α levels may have accelerated the periodontal healing observed in the clinical parameters.Clinical relevanceThe result of the present study demonstrated the beneficial effects of adjunctive i-PRF administration during non-surgical periodontal treatment of deep periodontal pockets.Clinical trial registration numberNCT05753631 (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Gingival crevicular fluid levels of apelin correlates with clinical periodontal diagnosis
ConclusionsWithin the limits of this study, it can be suggested that GCF apelin concentration may be a biomarker that can distinguish between healthy periodontal tissues, gingivitis, and periodontitis patients.Clinical relevanceApelin concentration in the gingival crevicular fluid may aid in the diagnosis of periodontal disease. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Do bioactive materials show greater retention rates in restoring permanent teeth than non-bioactive materials? A systematic review and network meta-analysis of randomized controlled trials
ConclusionBioactive restorative materials showed similar good clinical performance in terms of retention similarly to conventional resin composites.Clinical significanceThe findings must be interpreted with caution because many RCT on restorative materials aim to verify the equivalence of new materials over the gold standard material rather than their superiority. The present systematic review also suggests that new RCT with longer follow-up periods are necessary. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Decreased bone mineral density is associated with an increased number of teeth with periodontitis progression: a 5-year retrospective cohort study
ConclusionBaseline BMD in the osteoporosis range increased the risk of having a greater number of teeth with periodontitis progression in specific participant subgroups.Clinical RelevanceDecreased BMD is a potential factor affecting periodontitis progression risk in some individuals. Multidisciplinary approaches in educating and maintaining patients ’ bone-oral health may help improve their quality of life. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Extracapsular dissection via single cervical incision for parotid pleomorphic adenoma
ConclusionsECD via a single transverse cervical incision is a safe approach for benign parotid tumors, yielding excellent functional and disease control outcomes.Clinical relevanceThese findings can provide clinically meaningful minimally invasive recommendations to treat pleomorphic adenoma with minimal complications. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Evaluation of biochemical changes and treatment efficacy in patients with bruxism following botulinum toxin or splint therapy: a randomized clinical trial
ConclusionsStress and inflammatory biomarkers were found to be associated with bruxism. Cortisol levels decreased in people with bruxism after treatment with both occlusal splint and botox.Clinical relevanceBoth splint and botox treatments were effective for bruxism by reducing the stress levels. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
The potential use of ascorbic acid to recover the cellular senescence of lipopolysaccharide-induced human apical papilla cells: an in vitro study
ConclusionsLPS significantly promoted cellular senescence on hAPCs and diminished the cell function capacity. Co-presence of ascorbic acid could impede cellular senescence and possibly improve the regenerative capacity of LPS-induced senescent hAPCsin vitro.Clinical relevanceThe data support thein vitro potential benefit of ascorbic acid on cellular senescence recovery of apical papilla cells. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Pleiotropic effect of intramucosal injection of FTY720 on angiogenesis and tissue healing after free gingival graft surgery: a comparative experimental study in rabbits
ConclusionsThe findings indicate that the angiogenic effects of FTY-720 in the recipient site of free gingival graft can be employed to promote tissue healing and reduce scar tissue presence.Clinical relevanceA significant decrease in epithelial thickness and increase in angiogenesis as well as rete ridge formation score in the FTY-720 group were shown, which can be translated into improved tissue healing and less presence of scar tissue. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Correction to: Postoperative local interventions for the palate as a gingival graft donor area: a scoping review
(Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Retraction Note: Narrow- versus mini-implants at crestal and subcrestal bone levels. Experimental study in beagle dogs at three months
(Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Association between dental visit behavior and mortality: a nationwide longitudinal cohort study from NHANES
ConclusionsPoor dental visit behavior is associated with an increased risk of mortality. Further well-designed studies are needed to confirm the association between professional dental visit and mortality.Clinical relevanceThis study highlights the potential benefits of regular dental visits in maintaining general health. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 27, 2023 Category: Dentistry Source Type: research
A deep learning and radiomics fusion model based on contrast-enhanced computer tomography improves preoperative identification of cervical lymph node metastasis of oral squamous cell carcinoma
ConclusionA fusion model combining radiomics and deep learning approaches outperformed other single-technique models and showed great potential to accurately predict cervical LNM in patients with OSCC.Clinical relevanceThe fusion model can complement the preoperative identification of LNM of OSCC performed by the clinicians. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 27, 2023 Category: Dentistry Source Type: research
