The Effect of Sodium-Glucose Transporter 2 Inhibitors on Stroke in Patients With Type 2 Diabetes: A Meta-analysis
To provide an update on the effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on stroke in patients with type 2 diabetes (T2D). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 26, 2024 Category: Neurology Authors: Eric Pasqualotto, Farley Reis Rodrigues, Giovana Barros e Silva Ribeiro, Gustavo de Oliveira Almeida, J úlia Camargo Kabariti, Rafael Oliva Morgado Ferreira, Matheus Pedrotti Chavez, Mariana R.C. Clemente, Nicole B. Sur, Daniel G. Di Luca Source Type: research

Importance of Sex and Gender Differences in Enrollment and Interpretation of Stroke Clinical Trials
This review aims to reinforce the importance of improving sex balance in preclinical trials and sex and gender diversity and proportional balance in clinical trials enrollment and how this influences interpretation of stroke clinical trials. It also aims to identify strategies for improvement in data collection. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 25, 2024 Category: Neurology Authors: Tina M. Burton, Tracy E. Madsen, Rebecca Karb, Karen L. Furie Source Type: research

Association between the quantity of stroke care units and the complement of neurosurgical and neurology specialists in Japan: A retrospective study
Initial treatment in a stroke unit (SU) can reduce the mortality of stroke victims, increase the rate of discharge to home, and decrease the amount of time spent in the hospital. The effectiveness of an SU has also been proven in a meta-analysis. Stroke units have been established in various locations in Europe since 1990, and the medical system for managing the acute phase of stroke has improved1, 2. The Japanese Stroke Association recommends in its Stroke Treatment Guidelines 2021 that acute stroke patients should be treated by a multidisciplinary stroke team in an SU that provides intensive care and early rehabilitation...
Source: Journal of Stroke and Cerebrovascular Diseases - April 24, 2024 Category: Neurology Authors: Kentaro Hara, Masato Kanda, Hiroyo Kuwabara, Yoshio Kobayashi, Takahiro Inoue Source Type: research

A Systematic Review of the Epidemiology and The Public Health Implications of Stroke in Sub-Saharan Africa
With approximately 11 million strokes occurring annually worldwide, and over 6.5 million deaths annually, stroke has made its place as one of the major killers in the world. Although developing countries make up more than 4/5 of the global stroke burden, well-grounded information on stroke epidemiology remains lacking there. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 23, 2024 Category: Neurology Authors: Gisele Abissegue, Seidina Iliasu Yakubu, Aiswarya Seema Ajay, Faatihah Niyi-Odumosu Source Type: research

Application of Interpretable Machine Learning Algorithms to Predict Acute Kidney Injury in Patients with Cerebral Infarction in ICU
This study aimed to explore the application of interpretable machine learning algorithms in predicting AKI in patients with cerebral infarction. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2024 Category: Neurology Authors: Xiaochi Lu, Yi Chen, Gongping Zhang, Xu Zeng, Linjie Lai, Chaojun Qu Source Type: research

Quantitative Imaging for Predicting Hematoma Expansion in Intracerebral Hemorrhage: A Multimodel Comparison
Several studies report that radiomics provides additional information for predicting hematoma expansion in intracerebral hemorrhage (ICH). However, the comparison of diagnostic performance of radiomics for predicting revised hematoma expansion (RHE) remains unclear. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2024 Category: Neurology Authors: Wen-Song Yang, Jia-Yang Liu, Yi-Qing Shen, Xiong-Fei Xie, Shu-Qiang Zhang, Fang-Yu Liu, Jia-Lun Yu, Yong-Bo Ma, Zhong-Song Xiao, Hao-Wei Duan, Qi Li, Shan-Xiong Chen, Peng Xie Source Type: research

Prevalence of symptoms of post stroke depression and anxiety in young adults: a systematic review and meta-analysis
Young adults with stroke have distinct professional and social roles making them vulnerable to symptoms of post-stroke depression (PSD) and post-stroke anxiety (PSA). Prior reviews have examined the prevalence of anxiety and depression in stroke populations. However, there are a lack of studies that have focused on these conditions in young adults. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2024 Category: Neurology Authors: Katrina Hannah D. Ignacio, Ryan T. Muir, Jose Danilo B. Diestro, Nishita Singh, Melody Hope Lim Lee Yu, Omar El Omari, Rana Abdalrahman, Suzanne L. Barker-Collo, Maree L. Hackett, Sean P. Dukelow, Mohammed A. Almekhlafi Source Type: research

Protein kinase C-inhibition reduces critical weight loss and improves functional outcome after experimental subarachnoid haemorrhage
This study was undertaken to analyse functional outcomes up to 14 days after experimental SAH. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2024 Category: Neurology Authors: Jesper P B ömers, Anja Holm, Spyridoula Kazantzi, Professor Lars Edvinsson, Professor Tiit I Mathiesen, Kristian A Haanes Source Type: research

De Novo Brain Vascular Malformation in an Adult with Hereditary Hemorrhagic Telangiectasia and Juvenile Polyposis Overlap Syndrome
The development of brain vascular malformation (BVM) is rare in adults. The Hereditary Hemorrhagic Telangiectasia (HHT) Clinical Guidelines recommend BVM screening with magnetic resonance imaging (MRI) at the time of diagnosis. However, these guidelines apply broadly to the HHT population and do not account for patients with Mothers Against Decapentaplegic Homolog 4 (MADH4) mutations, often presenting other hypermobility features and cardiovascular anomalies (e.g., Aortic root aneurysms, vascular kinking). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 17, 2024 Category: Neurology Authors: Elisa Guan, Carolina Vazquez, Ana Braslavsky, Cristina H. Besada, Akly Manuel S. Perez, Oscar Peralta, Monaco Ricardo Garc ía, Matteo Baccanelli, Nicolás M. Ciarrocchi, Marcelo M. Serra Tags: Case Report Source Type: research

The Predictive Value of Serum F-actin on the Severity and Early Neurological Deterioration of Acute Ischemic Stroke
F-actin is involved in the progression of ischemic stroke and is associated with the disruption of the blood-brain barrier. In this article, we evaluated serum F-actin as a biomarker in stroke severity and early neurological deterioration (END) in acute ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 17, 2024 Category: Neurology Authors: Jiaqian Li, Binda Wang, Fangyu Dai, Xuelian Kou, Guangyong Wu, Bin Wu, Jie Xu, Lulan Pan, Jingjing Liu, Songbin He, Feng Gao Source Type: research

Health Care-Associated Infections after Surgical Treatment of Ruptured Intracranial Aneurysms
Aneurysmal subarachnoid hemorrhage (SAH) is catastrophic, and microsurgery for ruptured intracranial aneurysms is one of the preventive modalities for rebleeding. However, patients remain at high risk of medical morbidities after surgery, one of the most important of which is health care-associated infections (HAIs). We analyzed the incidence and risk factors of HAIs, as well as their association with the outcomes after surgical treatment of ruptured aneurysms. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2024 Category: Neurology Authors: Yu-Hua Huang, Tsung-Han Lee Source Type: research

Differentiating Ischemic Stroke Patients from Healthy Subjects Using a Large-Scale, Retrospective EEG Database and Machine Learning Methods
We set out to develop a machine learning model capable of distinguishing patients presenting with ischemic stroke from a healthy cohort of subjects. The model relies on a 3-minute resting electroencephalogram (EEG) recording from which features can be computed. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2024 Category: Neurology Authors: William Peterson, Nithya Ramakrishnan, Krag Browder, Nerses Sanossian, Peggy Nguyen, Ezekiel Fink Source Type: research

Systolic Blood Pressure Reduction Strategies in Acute Ischemic Stroke Patients Following Endovascular Thrombectomy: A Systematic Review and Meta-analysis
This study intends to investigate the relationship between reducing SBP and clinical outcomes and to determine the therapeutic efficacy of moderate and intensive SBP reduction post EVT. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2024 Category: Neurology Authors: Mohammed Maan Al-Salihi, Syed A. Gillani, Ram Saha, Mouhammad A. Jumaa, Syed F. Zaidi, Farhan Siddiq, Camilo R. Gomez, Mikael Mazhigi, Adnan I. Qureshi Source Type: research

An algorithm for the National Institute of Health Stroke Scale assessment: a multicenter, two-arm and cluster randomized study
The NIH Stroke Scale (NIHSS) is a validated tool for assessing stroke severity, increasingly used by general practitioners in telemedicine services. Mobile apps may enhance its reliability. We aim to validate a digital platform (SPOKES) for NIHSS assessment in telemedicine and healthcare settings. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2024 Category: Neurology Authors: Joao Brainer Clares de Andrade, Evelyn de Paula Pacheco, Millene Rodrigues Camilo, Carlos Eduardo Lenis Rodriguez, Paula Sanchez Nascimento, Nath ália Souza de Oliveira, Thiago S Carneiro, Renato Andre Castro de Oliveira, Gisele Sampaio Silva Source Type: research

A comparison of endovascular therapy and medical management in patients with large vessel occlusion mild stroke treated between 2015 and 2023: a systematic review and meta-analysis
Endovascular therapy (EVT) is recommended for patients with acute large-vessel occlusion (LVO) However, its efficacy and safety compared to medical management (MM) in patients with a National Institutes of Health Stroke Scale (NIHSS) score of ≤6 remains unclear. This meta-analysis compared EVT with medical MM in patients with large vessel occlusion mild stroke treated between 2015 and 2023, following the publication of the first randomized controlled trial. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 12, 2024 Category: Neurology Authors: Yiqiao Xu, Xin Liu, Hao Li Source Type: research