Masthead
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2018 Category: Neurology Source Type: research

Editorial Board
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2018 Category: Neurology Source Type: research

Table of Contents
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2018 Category: Neurology Source Type: research

Safety and Outcome of Endovascular Treatment for Minor Ischemic Stroke: Results From the Multicenter Clinical Registry of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands
Goal: Insufficient data is available about safety and efficacy of endovascular treatment (EVT) in patients with minor stroke symptoms because these patients were excluded from most randomized trials. We aimed to compare characteristics, functional outcome, and complications in patients with minor ischemic stroke National Institutes of Health Stroke Scale score ≤5 (NIHSS score ≤5) and moderate to severe ischemic stroke (NIHSS score ≥6) due to intracranial proximal artery occlusion of the anterior circulation who underwent EVT. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2018 Category: Neurology Authors: R.B. Goldhoorn, Maxim J.H.L. Mulder, Ivo G.H. Jansen, Wim H. van Zwam, Julie Staals, Aad van der Lugt, Diederik W.J. Dippel, Hester F. Lingsma, Jan Albert Vos, Jelis Boiten, Ido R. van den Wijngaard, Charles B.L.M. Majoie, Yvo B.W.E.M. Roos, Robert J. van Source Type: research

A Rare Case of Symptomatic Carotid Stenosis Caused by Mechanical Stimulation by Thyroid Cartilage and Frequent Swimming
Background: Bony structures around the carotid artery such as the styloid process and hyoid bone can cause dissection, compression, plaque formation, and plaque rupture of the carotid artery. To the best of our knowledge, this case is the first finding of thyroid cartilage being the cause of a lesion corresponding to adjacent common carotid artery (CCA) atherosclerosis. Case Description: A 51-year-old man with a history of hypertension and dyslipidemia suddenly experienced right facial numbness and dysphasia while front crawl swimming, which he usually did 3 times weekly. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2018 Category: Neurology Authors: Nobutoshi Kumagai, Yukiko Enomoto, Masafumi Miyai, Yusuke Egashira, Noriyuki Nakayama, Toru Iwama Source Type: research

Contrast-Induced Nephropathy in Ischemic Stroke Patients Undergoing Computed Tomography Angiography: CINISter Study
Goal: Computed tomography angiography (CTA) is a well-tolerated, noninvasive study of the intracranial vascular circulation; however, contrast-induced nephropathy (CIN) has been reported in 5%-7% of patients undergoing CTA. Limited studies have evaluated the risks of CIN in patients undergoing CTA. Our study was designed to evaluate the prevalence and risk factors for CIN in patients with ischemic stroke who receive a CTA. Materials and Methods: Single-center, nested, case-control study of patients with ischemic stroke who received a CTA between June 18, 2012 and January 1, 2016. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2018 Category: Neurology Authors: Anthony Shaun Rowe, Brandon Hawkins, Leslie A. Hamilton, Andrew Ferrell, Jennifer Henry, Brian F. Wiseman, Steven A. Skovran, Mitra S. Mosadegh, Marion E. Hare, Mehmet Kocak, Elizabeth Tolley Source Type: research

Intravenous Thrombolysis After Idarucizumab Application in Acute Stroke Patients —A Potentially Increased Sensitivity of Thrombi to Lysis?
Background: Rapid inactivation of dabigatran by its specific inhibitor idarucizamab allows intravenous thrombolysis (IVT) in patients suffering ischemic stroke while being treated with dabigatran. Only limited data of this approach is available and numerous questions regarding efficacy/safety remain to be answered. Herein, we present the findings from the Slovenian national cohort study. Methods: Retrospective analysis of all stroke patients treated with idarucizumab and IVT (n  = 11) in the period from July 2016 to February 2018 from Slovenian region were analyzed. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2018 Category: Neurology Authors: Janja Pretnar Oblak, Miso Sabovic, Senta Frol Source Type: research

Subacute Elevation of Plasma Level of Caspase-Cleaved Cytokeratin-18 is Associated with Hemorrhagic Transformation and Functional Outcome in Ischemic Stroke
Background: Caspase-cleaved cytokeratin-18 (CCCK-18) is an apoptosis marker. Here, we analyzed the relationship between plasma level of CCCK-18 in the acute and subacute stage of ischemic stroke and early and late functional outcome. Besides, correlation among CCCK-18 and complications, such as hemorrhagic transformation (HT) were also explored. Methods: Plasma concentration of CCCK-18 was investigated in 54 patients at admission and poststroke 72 hours. HT was evaluated by CT scans on 24 poststroke hours. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2018 Category: Neurology Authors: Tihamer Molnar, Kata Borocz, Timea Berki, Laszlo Szapary, Alex Szolics, Jozsef Janszky, Zsolt Illes, Peter Csecsei Source Type: research

Thrombectomy for Stroke at 6-24 hours without Perfusion CT Software for Patient Selection
This study aimed to elucidate the efficacy of thrombectomy 6-24 hours after onset in our patient cohort using conventional imaging mismatch. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2018 Category: Neurology Authors: Junya Tsurukiri, Takahiro Ota, Hiroyuki Jimbo, Eitaro Okumura, Keigo Shigeta, Tatsuo Amano, Masayuki Ueda, Yuji Matsumaru, Yoshiaki Shiokawa, Teruyuki Hirano Source Type: research

Plasma Levels of Brain-Derived Neurotrophic Factor are Associated with Prognosis in the Acute Phase of Ischemic Stroke
Context: Brain-derived neurotrophic factor (BDNF) is a neurotrophin involved in neuronal survival, differentiation, and maturation. Purpose: To evaluate the levels of BDNF in the acute phase of stroke and their potential association with neurological impairment. Methods: Patients in the acute phase of ischemic stroke were evaluated with the following clinical tools: National Institutes of Health Stroke Scale, modified Rankin scale, Gugging Swallowing Screen and Alberta Stroke Program Early CT Score. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 3, 2018 Category: Neurology Authors: Aline Mansueto Mour ão, Laélia Cristina Caseiro Vicente, Mery Natali Silva Abreu, Romeu Vale Sant'Anna, Erica Leandro Marciano Vieira, Leonardo Cruz de Souza, Aline Silva de Miranda, Milene Alvarenga Rachid, Antônio Lucio Teixeira Source Type: research

Angiographic Features of Intracranial Aneurysms in Ecuador
We describe the epidemiologic and angiographic features of ruptured and unruptured IAs in a cohort of patients from Ecuador.Methods: We conducted a retrospective analysis of prospectively acquired databases from 3 different tertiary hospitals over a 3-year period (2014-2017). In a per-patient basis, odd ratios (ORs) of ruptured presentation for each variable using a univariate logistic regression model were calculated. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - December 3, 2018 Category: Neurology Authors: Edgar A. Samaniego, Jorge A. Roa, Braulio Martinez-Burbano, Santiago Ortega-Gutierrez, David M. Hasan, Manuel Jibaja, James C. Torner, Nelson Maldonado Source Type: research

Value-Based Stroke Rehabilitation: Feasibility and Results of Patient-Reported Outcome Measures in the First Year After Stroke
This study aimed to evaluate the feasibility of a broad set of PROMs reflecting similar patient reported health domains as proposed within the International Standard Set of Patient-Centered Outcome Measures After Stroke within the first year after stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2018 Category: Neurology Authors: I.F. Groeneveld, P.H. Goossens, W. van Meijeren-Pont, H.J. Arwert, J.J.L. Meesters, A.D. Rambaran Mishre, F. Van Vree, T.P.M. Vliet Vlieland, SCORE-study group Source Type: research

High-Intensity Interval Training on Neuroplasticity, Balance between Brain-Derived Neurotrophic Factor and Precursor Brain-Derived Neurotrophic Factor in Poststroke Depression Rats
Background: High-intensity interval training (HIIT) improves functional and mental health in the patients with stroke. To investigate the potential mechanisms of HIIT on poststroke depression (PSD). Methods: Wistar rats were randomly divided into control, Sham, PSD, moderate intensity continuous training (MICT), and HIIT groups. After PSD model was successful made, the maximum speed (Smax) and the blood lactate threshold corresponding speed (SLT) were measured. Different intensity training protocols were performed on the MICT and HIIT groups, respectively. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2018 Category: Neurology Authors: Lu Luo, Congqin Li, Yu Deng, Yuyang Wang, Pingping Meng, Qiang Wang Source Type: research

Associations of β-Fibrinogen Polymorphisms with the Risk of Ischemic Stroke: A Meta-analysis
Recently, the roles of β-fibrinogen (FGβ) polymorphisms in ischemic stroke (IS) were intensively analyzed, but the results of these studies were inconsistent. Thus, we performed this study to better assess potential relationship between FGβ polymorphisms and the risk of IS. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 29, 2018 Category: Neurology Authors: Hailong Luo, Xin Li, Aiying Jiang, Benzhuo Zhang, Pengxiang Bi, Yan Dong, Yanqin Guo Source Type: research

Self-perceived and Actual Risk of Further Stroke in Patients with Recurrent Stroke or Recurrent Transient Ischemic Attack in Thailand
Background: The correct perception in patients of their future risk of recurrent stroke may lead to changes in behavior and to successful secondary prevention of stroke. The primary aim was to compare patients ’ perceived risk with the actual risk of further stroke. Methods: This cross-sectional study was carried out in 2 tertiary hospitals in northeast Thailand. Self-perceived risk of further stroke was assessed by validated questionnaire and categorized as low, medium, or high. Actual risk was calcula ted using Stroke Prognosis Instrument II which classified patients into 3 risk groups: low, medium, and high. (Sour...
Source: Journal of Stroke and Cerebrovascular Diseases - November 29, 2018 Category: Neurology Authors: Jittima Saengsuwan, Pathitta Suangpho Source Type: research

Platelet Aggregability as a Predictor of Restenosis Following Carotid Endarterectomy
Background: Antiplatelet drugs are administered before and after carotid endarterectomies (CEAs), but their efficacy for preventing restenosis remains unclear. Hence, this study aimed to identify associations between postoperative restenosis and platelet aggregability in CEA patients. Methods: Thirty-six consecutive CEA patients treated at Tokyo Women's Medical University from May 2013 to March 2015 were included in this retrospective study. Restenosis was defined as a stenosis ratio greater than or equal to 50% per the European Carotid Surgery Trial criteria or peak systolic velocity of 150 cm/s on carotid ultrasound. (So...
Source: Journal of Stroke and Cerebrovascular Diseases - November 29, 2018 Category: Neurology Authors: Yuichi Mochizuki, Tatsuya Ishikawa, Yasuo Aihara, Koji Yamaguchi, Takakazu Kawamata Source Type: research

Acute-Onset Ataxia and Transient Cerebellar Diffusion Restriction Associated with a PRRT2 Mutation
PRRT2 gene mutations cause paroxysmal kinesigenic dyskinesia (PKD), infantile convulsions, hemiplegic migraine, and episodic ataxia. A 21-year-old woman reported an episode of dizziness and ataxic gait occurring after swimming. Brain MRI showed a hyperintense cerebellar lesion on diffusion-weighted imaging (DWI) with decreased apparent diffusion coefficient. The clinical course was favorable. Both clinical and MRI abnormalities regressed. Her brother had presented PKD since adulthood. A C.649dupC PRRT2 truncating mutation was identified in both patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 28, 2018 Category: Neurology Authors: Nicolas Legris, Olivier Chassin, Ghaidaa Nasser, Florence Riant, Elisabeth Tournier-Lasserve, Christian Denier Tags: Case Report Source Type: research

Comparison of Motor Relearning Program versus Bobath Approach for Prevention of Poststroke Apathy: A Randomized Controlled Trial
Background: Apathy is a multidimensional syndrome referring to a primary lack of motivation, frequent in survivors of stroke. And prior studies have demonstrated the negative effect of apathy on recovery from stroke. Methods: A randomized controlled study of acute stroke patients. Four hundred and eighty-eight patients without evidence of apathy or depression at the initial visit were consecutively recruited, 258 males and 230 female. Patients were block randomized into 2 groups. Group A (n  = 245) and Group B (n = 243) had physiotherapy according to Motor Relearning Program and Bobath in the first 4 weeks, respect...
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2018 Category: Neurology Authors: Liping Chen, Siqing Xiong, Yi Liu, Meiqing Lin, Lu Zhu, Renjia Zhong, Jiuhan Zhao, Wenjing Liu, Jirui Wang, Xiuli Shang Source Type: research

Differences in Ischemic Anterior and Posterior Circulation Strokes: A Clinico-Radiological and Outcome Analysis
Background: There are limited data comparing posterior (PC) and anterior (AC) circulation acute ischemic strokes (AIS). We aimed to identify specific features of PC and AC strokes regarding clinical, etiological, radiological, and outcome factors. Methods: Patients from the Acute STroke Registry and Analysis of Lausanne, a prospective cohort of consecutive AIS, from years 2003 to 2008 were included. The stroke territory was determined by a combination of neuroimaging and clinical symptoms. Patients with uncertain localization or with simultaneous AC and PC strokes were excluded. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2018 Category: Neurology Authors: Elodie Z ürcher, Benjamin Richoz, Mohamed Faouzi, Patrik Michel Source Type: research

Prediabetes and Outcome of Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-analysis
Background: The association of prediabetes and outcome of patients with ischemic stroke or transient ischemic attack (TIA) remains controversial. We performed a systematic review and meta-analysis to assess the association between prediabetes and outcome of ischemic stroke or TIA.Methods: We comprehensively searched the PubMed and Excerpt Medica Database(EMBASE) from their inceptions to August 25, 2017. Studies that reported outcomes of patients with ischemic stroke or TIA and with information on prediabetic states at baseline were included. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 26, 2018 Category: Neurology Authors: Yuesong Pan, Weiqi Chen, Yongjun Wang Source Type: research

Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Rat Brain From Ischemia-Induced Damage
Background: Survival following cardiac arrest (CA) and subsequent cardiopulmonary resuscitation (CPR), to a great extent, depends on brain damage. Adipose-derived stem cells (ADSCs), as a source of paracrine growth factors and the capacity of neural differentiation may reduce this brain damage. Objective: The purpose of this study is to evaluate the protection of ADSCs to brain damage following CPR. Methods: Rats were divided into 3 groups, sham, CA, and ADSCs group. Rats in sham group went through sham surgery. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 25, 2018 Category: Neurology Authors: Bo Gong, Yongpin Dong, Chao He, Weiwei Jiang, Yi Shan, Betty Y. Zhou, Wenfang Li Source Type: research

Temporal Profile of CT and T2*-Weighted Gradient-Echo MRI in a Patient with Unilateral Thalamostriate Vein Thrombosis
Deep cerebral venous system thrombosis (DCVST) is an uncommon variety of thrombosis that accounts for 11% of cases of cerebral venous thrombosis. Thalamostriate vein (TSV) thrombosis is further rare among patients with DCVST. Although patients with cerebral venous thrombosis commonly have characteristic neurological deficits including headache, deterioration of consciousness, and seizures, patients with DCVST do not necessarily show such symptoms. Therefore, diagnose of DCVST is sometimes difficult. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2018 Category: Neurology Authors: Hikaru Kamo, Yuji Ueno, Mizuho Sugiyama, Nobukazu Miyamoto, Kazuo Yamashiro, Ryota Tanaka, Nobutaka Hattori Tags: Letter to the Editor Source Type: research

Modeling the Impact of Transcendental Meditation on Stroke Incidence and Mortality
Meditation has shown promise in clinical trials in reducing systolic blood pressure, one of the main risk factors for stroke. We aim to estimate the potential benefits of popularizing meditation on stroke incidence and mortality in the United States (U.S.). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2018 Category: Neurology Authors: Raj Anil Ambavane, Amin Khademi, Donglan Zhang, Lu Shi Source Type: research

Parity As a Protective Biomarker Against Silent Brain Infarction in Community-Dwelling Older Adults: The Sefuri Study
Background: Although several studies have reported an association between parity and increased risk of stroke, this relationship remains controversial. Aims: The present study aimed to determine whether parity is associated with silent brain infarction (SBI), independent of other confounders. Methods: We analyzed the brain magnetic resonance imaging findings in 576 of community-dwelling older adults with a mean age of 72.1 years. All female participants were asked to provide information regarding the total number of live births, their age at the last parity, and their age at menopause. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2018 Category: Neurology Authors: Hiroshi Yao, Kenji Fukuda, Yuko Araki, Yuki Takashima, Akira Uchino, Takefumi Yuzuriha, Manabu Hashimoto Source Type: research

Relationship between the Angle of the Posterior Inferior Cerebellar Artery and Cardioembolic Stroke
In patients with unilateral posterior inferior cerebellar artery (PICA) territory infarction, the absence of relevant vessel stenosis may make it difficult to determine the etiology of the infarction. The incidence of cardioembolic (CE) infarction and the factors associated with infarction in such patients remains largely unknown. We hypothesized that the PICA angle would affect the flow direction of embolic sources. Thus, we analyzed the association between high-risk CE sources and the PICA angle. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2018 Category: Neurology Authors: Sang Hun Lee, Jae Hyung Cha, Il Eok Jung, Sung Wook Yu, Ju Sun Moon, Kyung Hee Cho, Kyung Mi Oh, Chi Kyung Kim, Jin-Man Jung Source Type: research

Yield of Echocardiography in the Evaluation of Cerebral Ischemic Events: A Single Center Cohort Study
Background: Echocardiography (ECO) is frequently used as a screening test in patients with acute ischemic brain disease. We aimed to evaluate the additional information and therapeutic impact resulting from ECO in these patients. Methods: We conducted a prospective study performing ECO on consecutive patients with ischemic stroke or transient ischemic attacks, admitted to our centre between February 2013 and May 2017. Results: A total of 696 patients were included (female, 57.3%; mean age, 70 ± 15.3 years). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 22, 2018 Category: Neurology Authors: Alejandro M. Brunser, Rodrigo Iba ñez-Arenas, Martin Larico, Eloy Mansilla, Juan Almeida, Verónica V. Olavarría, Paula Muñoz, Alexis Rojo, Gabriel Cavada, Pablo M. Lavados Source Type: research

Primary Thrombectomy Versus Combined Mechanical Thrombectomy and Intravenous Thrombolysis in Large Vessel Occlusion Acute Ischemic Stroke
Mechanical thrombectomy (MT) in combination with intravenous thrombolysis (IVT) is the standard of care for patients with acute ischemic stroke with anterior circulation large vessel occlusion. The particular benefit of IVT in these patients is unknown. We performed a retrospective analysis of patients submitted to MT at our center between January 2015 and June 2017. Functional outcome was prospectively assessed using modified Rankin scale (mRS) at 3 months. A total of 234 patients were enrolled, 152 (65%) in the combined treatment group and 82 (35%) in the direct MT group. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 22, 2018 Category: Neurology Authors: Mariana Guimar ães Rocha, Andreia Carvalho, Marta Rodrigues, André Cunha, Sofia Figueiredo, António Martins de Campos, Tiago Gregório, Ludovina Paredes, Miguel Veloso, Pedro Barros, Sérgio Castro, Manuel Ribeiro, Henrique Costa Source Type: research

Masthead
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2018 Category: Neurology Source Type: research

Editorial Board
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2018 Category: Neurology Source Type: research

Table of Contents
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2018 Category: Neurology Source Type: research

Asymptomatic Coronary Artery Disease in Japanese Patients With the Acute Ischemic Stroke
To investigate the prevalence and outcomes of asymptomatic coronary artery disease (CAD) in patients with the first episode of ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2018 Category: Neurology Authors: Minoru Tagawa, Shigekazu Takeuchi, Yuichi Nakamura, Makihiko Saeki, Yoshinori Taniguchi, Tsukasa Ohno, Hiroyuki Watanabe, Yukie Ochiai, Kiminori Kato, Masaomi Chinushi, Yoshifusa Aizawa Source Type: research

Different Types of Family History of Stroke and Stroke Risk: Results Based on 655,552 Individuals
Many studies concentrated on the relationships between different types of family history and stroke, but they have not arrived at an unified conclusion. We conducted a comprehensive systematic review to further evaluate the associations. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2018 Category: Neurology Authors: Shumin Yu, Zhixia Su, Junyan Miao, Yuhui Yu, Shihan Zhang, Jiahua Wu, Huiting Zheng, Xueyang Zhang, Shiyao Zhong, Huilin Li, Li Qiao, Jie Liang, Minjie Chu, Tian Tian Source Type: research

Electronic Decision support for Improvement of Contemporary Therapy for Stroke Prevention
Despite ample clinical trial data demonstrating that oral anticoagulation (OAC) treatment is highly effective in reducing stroke for patients with atrial fibrillation (AF), OAC treatment remains underutilized in current clinical practice. Targeting hospitalist and emergency department providers with electronic decision support represents a potential quality improvement opportunity in the use of OAC medication in AF patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2018 Category: Neurology Authors: Seemant Chaturvedi, Adam G. Kelly, Shyam Prabhakaran, Gustavo Saposnik, Lilly Lee, Amer Malik, Christine Boerman, Gayle Serlin, Alejandro M. Mantero Source Type: research

Fish Consumption and Stroke Risk: A Meta-Analysis of Prospective Cohort Studies
Inconsistent results of the association between fish consumption and stroke risk have been indicated in previous epidemiological studies. Therefore, we performed a meta-analysis of prospective cohort studies to estimate the impact of fish consumption on stroke risk. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 20, 2018 Category: Neurology Authors: Wei Zhao, Hui Tang, Xiaodong Yang, Xiaoquan Luo, Xiaoya Wang, Chuan Shao, Jiaquan He Source Type: research

Heterotopic Ossification After Stroke: Clinical Profile and Severity of Ossification
Background and purpose: The aim of this study was to evaluate heterotopic ossification (HO) prevalence after stroke, describing clinical features and investigating predictors of HO and its severity. Methods: A cross-sectional study was carried out in 7 rehabilitation centers (Sarah Network) from 2004 to 2013. Results: Among 17,794 stroke cases, 235 patients (1.3%) presented clinical and radiological evidence of HO. A log-binomial model with robust variance estimated the prevalence ratio of 1.3% in 10 years. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 19, 2018 Category: Neurology Authors: Denise de Aquino Cunha, Sarah Camargos, Val éria Maria de Azeredo Passos, Carla de Meirelles Mello, Luiz Sérgio Vaz, Luciano Romero Soares de Lima Source Type: research

The Headache and Neck Pain in Ischemic Stroke Patients Caused by Cervicocerebral Artery Dissection. A Case-Control Study
The symptom of headache and neck pain is common in patients with cervicocerebral artery dissection (CAD). We attempt to screen ischemic stroke patients with CAD based on the characteristics of the pain. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 16, 2018 Category: Neurology Authors: Yuhan Wang, Wenchao Cheng, Yajun Lian Source Type: research

Pre-Existing Renal Failure Increases In-Hospital Mortality in Patients with Intracerebral Hemorrhage
To determine the clinical outcome for intracerebral hemorrhage (ICH) patients with pre-existing renal failure in the United States. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2018 Category: Neurology Authors: Rakesh Khatri, Mohammad Rauf Afzal, Mohtashim Arbaab Qureshi, Alberto Maud, Dou Huanyu, Gustavo Jose Rodriguez Source Type: research

Acute Corticonuclear Tract Ischemic Stroke with Isolated Central Facial Palsy
The clinical distinction between habitual facial asymmetry, early stage peripheral facial palsy, and isolated central facial palsy is sometimes difficult. The diagnosis of acute central facial palsy is of importance to identify patients for stroke work-up and appropriate treatment. We aimed to evaluate the prevalence and localization of acute ischemic lesions associated with isolated central facial palsy. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 13, 2018 Category: Neurology Authors: Marc E. Wolf, Hans-Werner Rausch, Philipp Eisele, Sonia Habich, Michael Platten, Angelika Alonso Source Type: research

A Regional Network Organization for Thrombectomy for Acute Ischemic Stroke in the Anterior Circulation; Timing, Safety, and Effectiveness
Mechanical thrombectomy (MT) in association with intravenous thrombolysis is recommended for treatment of acute ischemic stroke (AIS), with large vessel occlusion (LVO) in the anterior circulation. Because MT is only available in comprehensive stroke centers (CSC), the challenge of stroke organization is to ensure equitable access to the fastest endovascular suite. Our aim was to evaluate the feasibility, efficacy, and safety of MT in patients initially managed in 1 CSC (mothership), compared with patients first managed in primary stroke center (PSC), and then transferred to the CSC for MT (drip-and-ship). (Source: Journal...
Source: Journal of Stroke and Cerebrovascular Diseases - November 12, 2018 Category: Neurology Authors: Isabelle Mourand, Pauline Malissart, Cyril Dargazanli, Erika Nogue, Stephane Bouly, Nicolas Gaillard, Yassine Boukriche, Lucas Corti, Marie-Christine Picot, Olivier Beaufils, Mohamed Chbicheb, Denis Sablot, Alain Bonafe, Vincent Costalat, Caroline Arquiza Source Type: research

Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage
Correct diagnosis of cerebral stroke type, hemorrhagic or ischemic, is essential in the early stage to establish the optimum treatment. The diagnosis is mainly determined based on imaging studies. Other more available diagnostic methods are desirable, such as blood sample examination. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is very important in vascular dysfunction induced by oxidized low-density lipoprotein, including cell apoptosis. The present study evaluated LOX-1 as a biomarker for cerebral stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 12, 2018 Category: Neurology Authors: Takashi Inoue, Tomohisa Ishida, Tomoo Inoue, Atsushi Saito, Masayuki Ezura, Hiroshi Uenohara, Miki Fujimura, Kenichi Sato, Toshiki Endo, Shunsuke Omodaka, Hidenori Endo, Kuniyasu Niizuma, Teiji Tominaga Source Type: research

Aerobic Training Efficacy in Inflammation, Neurotrophins, and Function in Chronic Stroke Persons: A Randomized Controlled Trial Protocol
Background: Neuroinflammation is an important part of stroke pathophysiology and has both detrimental and beneficial effects after stroke. Besides that the enhancement of neurotrophins seems to be related to improvements in stroke recovery. Evidences suggest that exercise plays a role in modulating anti-inflammatory and neurotrophic effects. However, little is known about its impact in stroke survivors, mainly in chronic stroke. The purpose of this study is to investigate the efficacy of moderate-intensity treadmill exercise in changing inflammatory mediators, interleukin-6 (IL-6), soluble tumor necrosis factor receptors I...
Source: Journal of Stroke and Cerebrovascular Diseases - November 10, 2018 Category: Neurology Authors: Daniela Matos Garcia Oliveira, Larissa Tavares Aguiar, Marcus Vin ícius de Oliveira Limones, Aline Gonçalves Gomes, Luana Cristina da Silva, Christina Danielli Coelho de Morais Faria, Paula Luciana Scalzo Source Type: research

Vagal Nerve Palsy After Transarterial Embolization of Transverse-Sigmoid Dural Arteriovenous Fistula Using Onyx
We report a case of a 70-year-old man who developed a transverse-sigmoid dural arteriovenous fistula (TS-DAVF) that was successfully treated by transarterial embolization (TAE) with Onyx. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 10, 2018 Category: Neurology Authors: Sadayoshi Watanabe, Ichiro Nakahara, Tsuyoshi Ohta, Shoji Matsumoto, Ryota Ishibashi, Izumi Nagata Source Type: research

Positional Vertigo After Isolated Cerebellar Nodulus Stroke: A Report of 3 Cases
We report 3 cases (69-year-old man, 71-year-old man, and 82-year-old woman) of isolated cerebellar nodulus stroke patients, who presented with positional vertigo alone that lasted only for 2-4 days. Brain magnetic resonance imaging helped diagnosing these cases. Although rare, clinicians should be aware of isolated cerebellar nodulus stroke, when facing with patients with paroxysmal vertigo of acute onset. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 10, 2018 Category: Neurology Authors: Fuyuki Tateno, Ryuji Sakakibara Source Type: research

The Hippocratic Doctrine of “the Acute Brain Suffering” as the Brain Stroke
Background: The ancient Greek term "apoplexy" as is repeatedly mentioned by the Hippocratic School of Medicine, included a cluster of diseases, mainly those concerning the central nervous system. The term was wrongfully infiltrated in Western European medicine as synonymous to what is called today a "stroke" of the brain. Objective: While in "Corpus Hippocraticum" the definition of the stroke was rather ambiguous; our study aims to unveil those fragments referring to it, in order to compose the Hippocratic theory of what it stood for "Acute Brain Suffering" (Greek: Οξ&epsi...
Source: Journal of Stroke and Cerebrovascular Diseases - November 9, 2018 Category: Neurology Authors: Gregory Tsoucalas, Theodore G Papaioannou, Marianna Karamanou Source Type: research

Effect of Stride Management Assist Gait Training for Poststroke Hemiplegia: A Single Center, Open-Label, Randomized Controlled Trial
Poststroke gait disorders negatively impact activities of daily living. Rehabilitation for stroke patients is aimed at improving their walking ability, balance, and quality of life. Robot-assisted gait training (RAGT) is associated with an increased number of task-specific exercises, which may benefit poststroke motor learning. We investigated the effects of RAGT using Stride Management Assist (SMA, which increases walk ratio by inducing hip-joint flexion and extension) in subacute stroke patients with hemiplegia. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 9, 2018 Category: Neurology Authors: Naojiro Tanaka, Shinro Matsushita, Yasushi Sonoda, Yoshikatsu Maruta, Yuta Fujitaka, Masashi Sato, Miki Simomori, Rhyuki Onaka, Keiji Harada, Takashi Hirata, Shoji Kinoshita, Takatsugu Okamoto, Hitoshi Okamura Source Type: research

Risk Factors for Hemorrhagic and Cardioembolic Complications of Intracerebral Hemorrhage Associated with Anticoagulants
This study investigated hemorrhagic and cardioembolic events and risk factors in intracerebral hemorrhage patients taking anticoagulants. Methods: The clinical data of 65 consecutive intracerebral hemorrhage patients taking anticoagulants were retrospectively reviewed. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2018 Category: Neurology Authors: Sho Osawa, Tatsuya Shimizu, Tadashige Kano, Ryosuke Shintoku, Hiroya Fujimaki, Ken Asakura Source Type: research

The Influence of Weather on the Incidence of Primary Spontaneous Intracerebral Hemorrhage
Intracerebral hemorrhage has been associated with changes in various weather conditions. The primary aim of this study was to examine the collective influence of temperature, barometric pressure, and dew point temperature on the incidence of primary spontaneous intracerebral hemorrhage (sICH). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2018 Category: Neurology Authors: Rajeev Kumar Garg, Bichun Ouyang, Vishal Pandya, Raquel Garcia-Cano, Ivan Da Silva, Deborah Hall, Sayona John, Thomas Pritchett Bleck, Max Berkelhammer Source Type: research

The Role of Personalized Virtual Reality in Education for Patients Post Stroke —A Qualitative Case Series
Background: Education is essential to promote prevention of recurrent stroke and maximize rehabilitation; however, current techniques are limited and many patients remain dissatisfied. Virtual reality (VR) may provide an alternative way of conveying complex information through a more universal language. Aim: To develop and conduct preliminary assessments on the use of a guided and personalized 3D visualization education session via VR, for stroke survivors and primary caregivers. Methods: Four poststroke patients and their 4 primary caregivers completed the 3D visualization education session as well as pre- and postinterve...
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2018 Category: Neurology Authors: Angelica G Thompson-Butel, Christine T Shiner, John McGhee, Benjamin John Bailey, Pascal Bou-Haidar, Michael McCorriston, Steven G Faux Source Type: research

Hospital Quality Metrics: “America's Best Hospitals” and Outcomes After Ischemic Stroke
Background: Developing quality metrics to assess hospital-level care and outcomes is increasingly popular in the United States. The U.S. News& World Report ranking of “America's Best Hospitals” is an existing, popular hospital-profiling system, but it is unknown whether top-ranked hospitals in their report have better outcomes according to other hospital quality metrics such as the Centers for Medicare and Medicaid Services (CMS) publicly reported 30-day stro ke measures. Methods: The analysis was based on the 2015-2016 U.S. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2018 Category: Neurology Authors: Judith H. Lichtman, Erica C. Leifheit, Yun Wang, Larry B. Goldstein Source Type: research

Impact of Elevated Hemoglobin A1c Levels on Functional Outcome in Patients with Acute Ischemic Stroke
Background: The association between hemoglobin A1c (HbA1c) and clinical outcomes of acute ischemic stroke is uncertain. We aimed to evaluate the association between initial hemoglobin A1c level and clinical outcome after acute ischemic stroke.Methods: A total of 408 patients with first-ever acute ischemic stroke were included in this study. We divided the patients into three groups according to HbA1c level: low HbA1c level (HbA1c (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2018 Category: Neurology Authors: Hong Wang, Yifan cheng, Siyan Chen, Xianmei Li, Zhenguo Zhu, Wanli Zhang Source Type: research