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Association between sleep-disordered breathing and post-stroke fatigue in patients with ischemic stroke
Stroke is a leading cause of death and disability worldwide.[1] Post-stroke fatigue (PSF) refers to a self-reported lack of energy or increased need for rest that interferes with daily activities. [2] PSF is a common [3 –5] and often disabling symptom, [6,7] for which no evidence-based treatments exist, [8] and for which a clear pathophysiologic understanding is lacking. [4] Patients with greater PSF have higher rates of institutionalization and mortality, [9] lower likelihood of returning to work, [10] and reduc ed quality of life even after accounting for potential confounders such as depression and functional status. ...
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2024 Category: Neurology Authors: Christopher J. Becker, Lynda D. Lisabeth, Madeline Kwicklis, Xu Shi, Ronald D. Chervin, Erin Case, Devin L. Brown Source Type: research

Dual antiplatelet therapy versus intravenous tissue plasminogen activator with acute minor ischemic stroke: A systematic review and meta-analysis of safety and efficacy
Recent estimates of stroke incidence suggest that there are around 3 million new-onset strokes happening every year, of which nearly 30% are minor strokes 1. Acute ischemic stroke (AIS) is classified as "minor" if the National Institutes of Health Stroke Scale (NIHSS) score is low, usually between 0 and 3 2. However, minor AIS can still have significant clinical consequences as patients may experience long-term disability and may be at risk of recurrent strokes. Therefore, prompt diagnosis and treatment are critical to minimize complications 3. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2024 Category: Neurology Authors: Abdallah Abbas, Abdullah Ashraf Hamad, Mostafa Hossam El Din Moawad, Dalia Kamal Ewis, Rana Ahmed Youssef, Heba Hamouda, Malak A. Hassan, Mohammad Aladawi, Mohamed Elfil, Mostafa Meshref, Fawaz Al-Mufti Source Type: research

Thrombolysis treatment protected impairment of functional ability, quality of life and fatigue seven years after stroke
: We studied quality of life, functional outcome, depression, and fatigue of ischemic stroke patients treated with or without thrombolysis seven years post-stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2024 Category: Neurology Authors: Jaana K. Huhtakangas, Tarja Saaresranta, Moona Huhtakangas, Marianne Haapea, Juha Huhtakangas Source Type: research

The Role of Stroke Care Infrastructure on the Effectiveness of a Hub-and-Spoke Telestroke Model in South Carolina
To examine the relationship between stroke care infrastructure and stroke quality-of-care outcomes at 29 spoke hospitals participating in the hub-and-spoke telestroke network. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2024 Category: Neurology Authors: Mithuna Srinivasan, Amber Scott, Jackie Soo, Meera Sreedhara, Shena Popat, Kincaid Lowe Beasley, Tiara N. Jackson, Amena Abbas, W. Alexander Keaton, Christine Holmstedt, Jillian Harvey, Ryan Kruis, Shay McLeod, Roy Ahn Source Type: research

High fibrinogen-prealbumin ratio (FPR) predicts stroke-associated pneumonia
Stroke-associated pneumonia (SAP) is a common complication in acute ischemic stroke patients, approximately 14% of patients develop SAP after stroke1, 2. SAP is shown to be associated with poor functional prognosis, poor quality of life and early mortality after stroke3. Therefore, it is of great significance for seeking the early identification and treatment of SAP. However, the underlying mechanisms of SAP remain unclear. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2024 Category: Neurology Authors: Huihua Qiu, Xiaoqian Luan, Enci Mei Source Type: research

Pathologic Features of Brain Hemorrhage After Radiation Treatment: Case Series with Somatic Mutation Analysis
Benefits of radiation treatment are severely limited by adverse radiation effects (ARE), also referred to as radionecrosis, with a reported incidence of 5-68% after brain irradiation1. Clinical and imaging definitions have not been consistent2, and the specific prevalence of brain bleeding within the context of ARE is not known. Pathologic substrates and molecular features of hemorrhagic ARE have not been systematically studied3. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2024 Category: Neurology Authors: Roberto J Alcazar-Felix, Abhinav Srinath, Stephanie Hage, Akash Bindal, Andrew Ressler, Peter Pytel, Sammy Allaw, Romuald Girard, Douglas A Marchuk, Issam A Awad, Sean P Polster Source Type: research

Assessment of the Safety and Efficacy of the Zoom (45 and 55) Reperfusion Catheters for Medium and Distal Mechanical Thrombectomies: A Multi-Institutional Study
This study evaluates their utility in medium and distal vessel occlusions. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 24, 2024 Category: Neurology Authors: Tritan Plute, Gautam Nayar, Joshua Weinberg, Alexander Keister, Hussam Abou-Al-Shaar, Alhamza R. Al-Bayati, Raul G. Nogueira, Michael J. Lang, Shahid Nimjee, Bradley Gross Source Type: research

Shikonin attenuates cerebral ischemia/reperfusion injury via inhibiting NOD2/RIP2/NF- κB-mediated microglia polarization and neuroinflammation
Ischemic stroke is well-established as the second most common cause of morbidity and mortality worldwide, posing a significant threat to human health 1, 2. Restoring cerebral blood supply by revascularization is the most effective treatment for ischemic stroke 3. Currently, administration of tissue plasminogen activator (tPA) or mechanical thrombectomy to restore brain reperfusion is the standard treatment strategy for ischemic patients 4. Nevertheless, the proportion of individuals who benefit from these interventions is less than 10% owing to strict indications and short time window problems 5. (Source: Journal of Stroke...
Source: Journal of Stroke and Cerebrovascular Diseases - March 23, 2024 Category: Neurology Authors: Ya Yang, Yuxiang Fei, Xuejiao Xu, Jun Yao, Jianing Wang, Chao Liu, Haiyan Ding Source Type: research

Correlation between lesion location and dysphagia characteristics in post-stroke patients
To assess the correlation between lesion location and swallowing function characteristics in post-stroke dysphagia (PSD) patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 22, 2024 Category: Neurology Authors: Qing-lu Yang, Yang Chen, Xue-jie Wang, Hui-ying Qiu, Meng-ting Chen, Xu-hui Zhou, Chu-yao Jian, Shao-feng Zhao Source Type: research

The discovery of GGT1 as a novel gene for ischemic stroke conferring protection against disease risk in non-smokers and non-abusers of alcohol
According to the Global Stroke Factsheet 20221, the lifetime risk of developing stroke has increased by 50% in the last 17 years. Ischemic stroke is the most common stroke type caused by a thrombotic or embolic event that causes a decrease in blood flow to the brain, leading to hypoxia and necrosis of the brain tissue2,3. Increased death rates and long-term disability due to ischemic stroke in recent decades, especially in the working-age population4, require the improvement of existing methods for early diagnosis and treatment of patients with cerebrovascular disease and the implementation of effective primary prevention ...
Source: Journal of Stroke and Cerebrovascular Diseases - March 22, 2024 Category: Neurology Authors: Maria Solodilova, Elena Drozdova, Iuliia Azarova, Elena Klyosova, Marina Bykanova, Olga Bushueva, Anna Polonikova, Mikhail Churnosov, Alexey Polonikov Source Type: research

Genetically predicted high serum sex hormone-binding globulin levels are associated with lower ischemic stroke risk: a sex-stratified Mendelian randomization study
Cross-sectional and cohort studies have found insufficient evidence of a causal relationship between sex hormone-binding globulin and ischemic stroke, only associations. Here, we performed a sex-stratified, bidirectional, two-sample Mendelian randomization analysis to evaluate whether a causal relationship exists between sex hormone-binding globulin and ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 22, 2024 Category: Neurology Authors: Wei Sun, Yuan Wang, Cancan Li, Xuefan Yao, Xiao Wu, Aini He, Benke Zhao, Xiaoqin Huang, Haiqing Song Source Type: research

Identification of Differentially Expressed Autophagy-related Genes in cases of Intracranial Aneurysm: Bioinformatics Analysis
This study aimed to examine and validate potential autophagy-related genes (ARGs) in cases of IA using bioinformatics analysis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2024 Category: Neurology Authors: Han Zhou, Yangcheng Song, Chao Wang, Quanzhou Zhu, Yugong Feng Source Type: research

Outcomes of Acute Ischemic Stroke Among Patients with Renal Cell Carcinoma: A Nationwide Analysis
Renal cell carcinoma (RCC) has been associated with an increased risk for acute ischemic stroke (AIS). As individuals with cancer who experience AIS tend to face higher mortality rates compared to AIS patients without cancer, recognizing the implications of RCC in AIS is crucial for identifying high-risk patients for major complications and directing management strategies. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2024 Category: Neurology Authors: Galadu Subah, Sabrina Zeller, Aarti Jain, Emma Bloom, Saya Mieth, Nimrod Gozum, Austin Li, Fangyi Lin, Anaz Uddin, Stuart Brill, Tarik Al-Bermani, Gurmeen Kaur, Chirag D. Gandhi, Fawaz Al-Mufti Source Type: research

Factors Associated with Clopidogrel Resistance and Clinical Outcomes in Ischemic Cerebrovascular Disease: A Retrospective Study
Clopidogrel resistance may lead to the recurrence of cerebrovascular diseases. We aimed to identify potential factors associated with clopidogrel resistance and evaluate the clinical outcomes of the patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 19, 2024 Category: Neurology Authors: Yanzi Wu, Huachao Shen, Biyang Cai, Chen Chen, Qiong Yin, Yulei Zhao, Guohua Zhou Source Type: research

Optimal intraventricular hemorrhage volume cutoff for predicting poor outcome in patients with intracerebral hemorrhage
The prognosis of patients with spontaneous intracerebral hemorrhage (ICH) is often influenced by hematoma volume, a well-established predictor of poor outcome. However, the optimal intraventricular hemorrhage (IVH) volume cutoff for predicting poor outcome remains unknown. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 19, 2024 Category: Neurology Authors: Lan Deng, Jiang-Tao Zhang, Xin-Ni Lv, Zuo-Qiao Li, Chu Chen, Xiao Hu, Hao Yin, Tian-Nan Yang, Zhe-Hao Zhang, Qi Li Source Type: research