Intravenous Thrombolysis for Stroke Patients with G6PD Deficiency
No reports regarding the safety of thrombolysis in acute stroke patients with a G6PD deficiency have been published to date. Here we aimed to evaluate the safety of intravenous thrombolysis for G6PD-deficient stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Xiaoyan Wu, Ruying Fu, Yamei Tang, Li Shi, Xiaoming Rong, Jianjun Guo, Jie Li, Qingyu Shen Source Type: research

Unique Angiographic Appearances of Moyamoya Disease Detected with 3-Dimensional Rotational Digital Subtraction Angiography Imaging Showing the Hemodynamic Status
The aim of this study was to identify the unique morphological arterial features in patients with moyamoya disease on 3-dimensional rotational digital subtraction angiography. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Jun Karakama, Tadashi Nariai, Shoko Hara, Shihori Hayashi, Kazutaka Sumita, Motoki Inaji, Yoji Tanaka, Kei Wagatsuma, Kenji Ishii, Shigeru Nemoto, Taketoshi Maehara Source Type: research

Urgent Detection of Acute Type A Aortic Dissection in Hyperacute Ischemic Stroke or Transient Ischemic Attack
Urgent diagnosis of acute Stanford type A aortic dissection (AAD) in patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA) is sometimes challenging. We assessed predictive values for markers of AAD in patients with AIS or TIA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Naoki Tokuda, Masatoshi Koga, Tomoyuki Ohara, Kenji Minatoya, Yoshio Tahara, Masahiro Higashi, Yuichi Miyazaki, Katsufumi Kajimoto, Soichiro Matsubara, Naoki Makita, Yuki Sakamoto, Yasuyuki Iguchi, Toshiki Mizuno, Kazuyuki Nagatsuka, Kazunori Toyoda Source Type: research

The Impacts of Peptic Ulcer on Stroke Recurrence
This study aimed to evaluate the impacts of peptic ulcer on stroke recurrence and mortality. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Zongliang Xu, Ling Wang, Ying Lin, Zhaojun Wang, Yun Zhang, Junrong Li, Shenghua Li, Zusen Ye, Kunxiong Yuan, Wanying Shan, Xinfeng Liu, Xinying Fan, Gelin Xu Source Type: research

Intravenous Thrombolysis for Stroke Patients with G6PD Deficiency
No reports regarding the safety of thrombolysis in acute stroke patients with a G6PD deficiency have been published to date. Here we aimed to evaluate the safety of intravenous thrombolysis for G6PD-deficient stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Xiaoyan Wu, Ruying Fu, Yamei Tang, Li Shi, Xiaoming Rong, Jianjun Guo, Jie Li, Qingyu Shen Source Type: research

Unique Angiographic Appearances of Moyamoya Disease Detected with 3-Dimensional Rotational Digital Subtraction Angiography Imaging Showing the Hemodynamic Status
The aim of this study was to identify the unique morphological arterial features in patients with moyamoya disease on 3-dimensional rotational digital subtraction angiography. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Jun Karakama, Tadashi Nariai, Shoko Hara, Shihori Hayashi, Kazutaka Sumita, Motoki Inaji, Yoji Tanaka, Kei Wagatsuma, Kenji Ishii, Shigeru Nemoto, Taketoshi Maehara Source Type: research

Urgent Detection of Acute Type A Aortic Dissection in Hyperacute Ischemic Stroke or Transient Ischemic Attack
Urgent diagnosis of acute Stanford type A aortic dissection (AAD) in patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA) is sometimes challenging. We assessed predictive values for markers of AAD in patients with AIS or TIA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Naoki Tokuda, Masatoshi Koga, Tomoyuki Ohara, Kenji Minatoya, Yoshio Tahara, Masahiro Higashi, Yuichi Miyazaki, Katsufumi Kajimoto, Soichiro Matsubara, Naoki Makita, Yuki Sakamoto, Yasuyuki Iguchi, Toshiki Mizuno, Kazuyuki Nagatsuka, Kazunori Toyoda Source Type: research

The Impacts of Peptic Ulcer on Stroke Recurrence
This study aimed to evaluate the impacts of peptic ulcer on stroke recurrence and mortality. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2018 Category: Neurology Authors: Zongliang Xu, Ling Wang, Ying Lin, Zhaojun Wang, Yun Zhang, Junrong Li, Shenghua Li, Zusen Ye, Kunxiong Yuan, Wanying Shan, Xinfeng Liu, Xinying Fan, Gelin Xu Source Type: research

Therapeutic Decisions in Atrial Fibrillation for Stroke Prevention: The Role of Aversion to Ambiguity and Physicians' Risk Preferences
Knowledge-to-action gaps influence therapeutic decisions in atrial fibrillation (AF). Physician-related factors are common, but the least studied. We evaluated the prevalence and determinants of physician-related factors and knowledge-to-action gaps among physicians involved in the management of AF patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2018 Category: Neurology Authors: Luciano A. Sposato, Devin Stirling, Gustavo Saposnik Source Type: research

Assessment of Temporomandibular Joint Dysfunction in Patients with Stroke
The aim of this study was to assess temporomandibular joint dysfunction in patients with stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2018 Category: Neurology Authors: Ömer Dursun, Tamer Çankaya Source Type: research

Is the Population Detected by Screening in China Truly at High Risk of Stroke?
The Chinese Stroke Screening and Prevention Project (CSSPP) considers patients with 3 or more risk factors to be at high risk of stroke, and does not quantitatively assess the risk for stroke. However, to detect high-risk groups more efficiently, a health risk appraisal (HRA) model should be used to assess individual risk of stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2018 Category: Neurology Authors: Yuan Wang, Jing Wang, Juan Cheng, Xuan Liang, Xin Li, Wenli Lu Source Type: research

Therapeutic Decisions in Atrial Fibrillation for Stroke Prevention: The Role of Aversion to Ambiguity and Physicians' Risk Preferences
Knowledge-to-action gaps influence therapeutic decisions in atrial fibrillation (AF). Physician-related factors are common, but the least studied. We evaluated the prevalence and determinants of physician-related factors and knowledge-to-action gaps among physicians involved in the management of AF patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2018 Category: Neurology Authors: Luciano A. Sposato, Devin Stirling, Gustavo Saposnik Source Type: research

Assessment of Temporomandibular Joint Dysfunction in Patients with Stroke
The aim of this study was to assess temporomandibular joint dysfunction in patients with stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2018 Category: Neurology Authors: Ömer Dursun, Tamer Çankaya Source Type: research

Is the Population Detected by Screening in China Truly at High Risk of Stroke?
The Chinese Stroke Screening and Prevention Project (CSSPP) considers patients with 3 or more risk factors to be at high risk of stroke, and does not quantitatively assess the risk for stroke. However, to detect high-risk groups more efficiently, a health risk appraisal (HRA) model should be used to assess individual risk of stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2018 Category: Neurology Authors: Yuan Wang, Jing Wang, Juan Cheng, Xuan Liang, Xin Li, Wenli Lu Source Type: research

Ischemic Stroke Secondary to Paradoxical Embolism Through a Pulmonary Arteriovenous Malformation: Case Report and Review of the Literature
We report a 32-year-old man who presented with an abrupt onset of right facial weakness and expressive aphasia. Brain magnetic resonance imaging revealed an acute infarct in the left middle cerebral artery territory and chronic infarcts in the bilateral cerebellar hemispheres. A cardioembolic mechanism was initially considered in the setting of perimyocarditis diagnosed a few months earlier. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 5, 2018 Category: Neurology Authors: Ryan Cappa, Jeanette Du, Joseph F. Carrera, Jimmy V. Berthaud, Andrew M. Southerland Tags: Case Studies Source Type: research

Stroke in Human Immunodeficiency Virus-infected Individuals in Sub-Saharan Africa (SSA): A Systematic Review
Human immunodeficiency virus (HIV) infection is associated with worse outcomes after stroke, but this association is less well-described in sub-Saharan Africa (SSA). We reviewed literature on stroke among people living with HIV (PLWH) in SSA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 5, 2018 Category: Neurology Authors: Amir Abdallah, Jonathan L. Chang, Cumara B. O'Carroll, Abdu Musubire, Felicia C. Chow, Anthony L. Wilson, Mark J. Siedner Source Type: research

Ischemic Stroke Secondary to Paradoxical Embolism Through a Pulmonary Arteriovenous Malformation: Case Report and Review of the Literature
We report a 32-year-old man who presented with an abrupt onset of right facial weakness and expressive aphasia. Brain magnetic resonance imaging revealed an acute infarct in the left middle cerebral artery territory and chronic infarcts in the bilateral cerebellar hemispheres. A cardioembolic mechanism was initially considered in the setting of perimyocarditis diagnosed a few months earlier. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 5, 2018 Category: Neurology Authors: Ryan Cappa, Jeanette Du, Joseph F. Carrera, Jimmy V. Berthaud, Andrew M. Southerland Tags: Case Studies Source Type: research

Stroke in Human Immunodeficiency Virus-infected Individuals in Sub-Saharan Africa (SSA): A Systematic Review
Human immunodeficiency virus (HIV) infection is associated with worse outcomes after stroke, but this association is less well-described in sub-Saharan Africa (SSA). We reviewed literature on stroke among people living with HIV (PLWH) in SSA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 5, 2018 Category: Neurology Authors: Amir Abdallah, Jonathan L. Chang, Cumara B. O'Carroll, Abdu Musubire, Felicia C. Chow, Anthony L. Wilson, Mark J. Siedner Source Type: research

Comparison of Nicardipine with Clevidipine in the Management of Hypertension in Acute Cerebrovascular Diseases
In acute stroke, hypertension worsens outcomes. Guidelines do not mention a preferred antihypertensive agent. This present study aimed to compare the efficacy and safety of nicardipine and clevidipine in acute stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 4, 2018 Category: Neurology Authors: Zachary Rosenfeldt, Katelyn Conklen, Breck Jones, Don Ferrill, Maithili Deshpande, Fazeel M. Siddiqui Source Type: research

Spontaneous Micro-Aggregation of Platelets Predicts Clinical Outcome in Acute Ischemic Stroke
Spontaneous micro-aggregation of platelets (SMAP) is frequently observed in stroke patients and is a trigger for the additional development of larger thrombi. We tested the hypothesis that SMAP may predict clinical outcome in acute ischemic stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 4, 2018 Category: Neurology Authors: Risa Kudoh, Kasumi Mikami, Maiko Kitajima, Keiko Aizu, Yui Kitajima, Joji Hagii, Hirofumi Metoki, Satoshi Seino, Yoshiko Baba, Minoru Yasujima, Tomohiro Osanai Source Type: research

Comparison of Nicardipine with Clevidipine in the Management of Hypertension in Acute Cerebrovascular Diseases
In acute stroke, hypertension worsens outcomes. Guidelines do not mention a preferred antihypertensive agent. This present study aimed to compare the efficacy and safety of nicardipine and clevidipine in acute stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 4, 2018 Category: Neurology Authors: Zachary Rosenfeldt, Katelyn Conklen, Breck Jones, Don Ferrill, Maithili Deshpande, Fazeel M. Siddiqui Source Type: research

Spontaneous Micro-Aggregation of Platelets Predicts Clinical Outcome in Acute Ischemic Stroke
Spontaneous micro-aggregation of platelets (SMAP) is frequently observed in stroke patients and is a trigger for the additional development of larger thrombi. We tested the hypothesis that SMAP may predict clinical outcome in acute ischemic stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 4, 2018 Category: Neurology Authors: Risa Kudoh, Kasumi Mikami, Maiko Kitajima, Keiko Aizu, Yui Kitajima, Joji Hagii, Hirofumi Metoki, Satoshi Seino, Yoshiko Baba, Minoru Yasujima, Tomohiro Osanai Source Type: research

Impact of Stroke Call on the Stroke Neurology Workforce in the United States: Possible Challenges and Opportunities
The Stroke& Vascular Neurology Section of the American Academy of Neurology was charged to identify challenges to the recruitment and retention of stroke neurologists and to make recommendations to address any identified problems. The Section initiated this effort by determining the impact of stroke on-call requirements as a barrier to the recruitment and retention of vascular neurologists. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 3, 2018 Category: Neurology Authors: Edgar J. Kenton, Antonio Culebras, Pierre B. Fayad, Larry B. Goldstein, Brian Kaskie, Enrique C. Leira, Helmi L. Lutsep, Lawrence R. Wechsler, Jos é Biller, Irene L. Katzan, James C. Stevens, David Z. Wang, Nellie Adams, Carolyn Cahill, AAN Vascular Neur Source Type: research

A Reanalysis of Predictors for the Risk of Hemorrhage in Brain Arteriovenous Malformation
Brain arteriovenous malformation (BAVM) is a congenital cerebral vascular disease that characterized with intracranial hemorrhage and epilepsy. It has some risk in current treatments including microsurgery, endovascular, and radiation therapy. Some patients with bAVMs may keep unruptured in their whole life. Whether it should be treated depends on the evaluation of the hemorrhage risk of bAVM. Although previous studies gave many significant predictors, we tried to find some new and more significant predictors in 173 patients with bAVMS by retrospective analysis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 2, 2018 Category: Neurology Authors: Zheng Huang, Kang Peng, Changqing Chen, Feiyue Zeng, Junyu Wang, Fenghua Chen Source Type: research

Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone —Pilot Study
Currently there are no pharmacological therapies for patients with unruptured cerebral aneurysms. Elsewhere we showed that the mineralocorticoid receptor antagonist eplerenone prevented the formation of cerebral aneurysms in our ovariectomized hypertensive aneurysm rat model. The current pilot study evaluated whether it can be used to prevent the growth and rupture of cerebral aneurysms in hypertensive patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 2, 2018 Category: Neurology Authors: Shinji Nagahiro, Yoshiteru Tada, Junichiro Satomi, Tomoya Kinouchi, Kazuyuki Kuwayama, Kenji Yagi, Kohei Nakajima, Nobuhisa Matsushita, Takeshi Miyamoto, Tadashi Yamaguchi, Kenji Shimada, Masaaki Korai, Hideo Mure, Yoshihiro Okayama, Takashi Abe, Masafumi Source Type: research

A Reanalysis of Predictors for the Risk of Hemorrhage in Brain Arteriovenous Malformation
Brain arteriovenous malformation (BAVM) is a congenital cerebral vascular disease that characterized with intracranial hemorrhage and epilepsy. It has some risk in current treatments including microsurgery, endovascular, and radiation therapy. Some patients with bAVMs may keep unruptured in their whole life. Whether it should be treated depends on the evaluation of the hemorrhage risk of bAVM. Although previous studies gave many significant predictors, we tried to find some new and more significant predictors in 173 patients with bAVMS by retrospective analysis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 2, 2018 Category: Neurology Authors: Zheng Huang, Kang Peng, Changqing Chen, Feiyue Zeng, Junyu Wang, Fenghua Chen Source Type: research

Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone —Pilot Study
Currently there are no pharmacological therapies for patients with unruptured cerebral aneurysms. Elsewhere we showed that the mineralocorticoid receptor antagonist eplerenone prevented the formation of cerebral aneurysms in our ovariectomized hypertensive aneurysm rat model. The current pilot study evaluated whether it can be used to prevent the growth and rupture of cerebral aneurysms in hypertensive patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 2, 2018 Category: Neurology Authors: Shinji Nagahiro, Yoshiteru Tada, Junichiro Satomi, Tomoya Kinouchi, Kazuyuki Kuwayama, Kenji Yagi, Kohei Nakajima, Nobuhisa Matsushita, Takeshi Miyamoto, Tadashi Yamaguchi, Kenji Shimada, Masaaki Korai, Hideo Mure, Yoshihiro Okayama, Takashi Abe, Masafumi Source Type: research

Cytokine Response, Tract-Specific Fractional Anisotropy, and Brain Morphometry in Post-Stroke Cognitive Impairment
Post-stroke cognitive impairment is a clinically heterogeneous condition and its types have a different course and prognosis. The aim of the present study is to address the roles of inflammation, white matter pathology, and brain atrophy in different neuropsychological types of cognitive impairment in the acute period of ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Aleksey Kulesh, Viktor Drobakha, Elena Kuklina, Irina Nekrasova, Vladimir Shestakov Source Type: research

Botulinum Toxin Type A Treatment Combined with Intensive Rehabilitation for Gait Poststroke: A Preliminary Study
To examine the effects of botulinum toxin type A (BoNT-A) treatment combined with intensive rehabilitation for gait compared with intensive rehabilitation alone in patients with chronic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Yuki Uchiyama, Tetsuo Koyama, Yosuke Wada, Masashi Katsutani, Norihiko Kodama, Kazuhisa Domen Source Type: research

Initial Experience with a Flow Redirection Endoluminal Device Stent —A Brazilian Multicenter Study
The endovascular approach has become the therapy of choice for intracranial aneurysms.1-3 However, certain types of cerebral aneurysms, particularly wide-necked, large, and fusiform aneurysms, still pose a treatment challenge.4 The development of flow-diverter (FD) stents has offered the potential of aneurysm occlusion by vessel reconstruction, thus being an excellent choice for treating these complicated lesions. The classic FDs are the Pipeline embolization device (PED; Covidien, Irvine, CA) and the SILK flow diverter (SFD; Balt Extrusion, Montmorency, France), but in recent years, new devices have become available on th...
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Luciano B. Manzato, Rafael B. Santos, Daniela O. Teixeira, Paulo M. Mesquita Filho, N ério D. Azambuja, Leonardo Frighetto, José R. Vanzin Tags: Case Studies Source Type: research

Impact of General Practitioner Transient Ischemic Attack Training on 90-Day Stroke Outcomes: Secondary Analysis of a Cluster Randomized Controlled Trial
Many patients with transient ischemic attack (TIA) receive initial assessments by general practitioners (GPs) who may lack TIA management experience. In a randomized controlled trial (RCT), we showed that electronic decision support for GPs improves patient outcomes and guideline adherence. Some stroke services prefer to improve referrer expertise through TIA/stroke education sessions instead of promoting TIA decision aids or triaging tools. This is a secondary analysis of whether a GP education session influenced TIA management and outcomes. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Annemarei Ranta, Susan Dovey, John Gommans, Murray Tilyard, Mark Weatherall Source Type: research

Paradoxical Association of Symptomatic Local Vasogenic Edema with Global Cerebral Hypoperfusion after Direct Revascularization Surgery for Adult Moyamoya Disease
Superficial temporal artery –middle cerebral artery (STA–MCA) anastomosis is the standard treatment for Moyamoya disease (MMD). Cerebral hyperperfusion syndrome is a potential complication of this procedure and can cause local vasogenic edema and/or delayed intracerebral hemorrhage. Cerebral hypoperfusion is a contradictor y postoperative pathophysiological condition implicated in MMD, but its association with symptomatic local vasogenic edema has not been reported. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Ryosuke Tashiro, Miki Fujimura, Shunji Mugikura, Kuniyasu Niizuma, Hidenori Endo, Toshiki Endo, Teiji Tominaga Tags: Case Studies Source Type: research

Cytokine Response, Tract-Specific Fractional Anisotropy, and Brain Morphometry in Post-Stroke Cognitive Impairment
Post-stroke cognitive impairment is a clinically heterogeneous condition and its types have a different course and prognosis. The aim of the present study is to address the roles of inflammation, white matter pathology, and brain atrophy in different neuropsychological types of cognitive impairment in the acute period of ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Aleksey Kulesh, Viktor Drobakha, Elena Kuklina, Irina Nekrasova, Vladimir Shestakov Source Type: research

Botulinum Toxin Type A Treatment Combined with Intensive Rehabilitation for Gait Poststroke: A Preliminary Study
To examine the effects of botulinum toxin type A (BoNT-A) treatment combined with intensive rehabilitation for gait compared with intensive rehabilitation alone in patients with chronic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Yuki Uchiyama, Tetsuo Koyama, Yosuke Wada, Masashi Katsutani, Norihiko Kodama, Kazuhisa Domen Source Type: research

Initial Experience with a Flow Redirection Endoluminal Device Stent —A Brazilian Multicenter Study
The endovascular approach has become the therapy of choice for intracranial aneurysms.1-3 However, certain types of cerebral aneurysms, particularly wide-necked, large, and fusiform aneurysms, still pose a treatment challenge.4 The development of flow-diverter (FD) stents has offered the potential of aneurysm occlusion by vessel reconstruction, thus being an excellent choice for treating these complicated lesions. The classic FDs are the Pipeline embolization device (PED; Covidien, Irvine, CA) and the SILK flow diverter (SFD; Balt Extrusion, Montmorency, France), but in recent years, new devices have become available on th...
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Luciano B. Manzato, Rafael B. Santos, Daniela O. Teixeira, Paulo M. Mesquita Filho, N ério D. Azambuja, Leonardo Frighetto, José R. Vanzin Tags: Case Studies Source Type: research

Impact of General Practitioner Transient Ischemic Attack Training on 90-Day Stroke Outcomes: Secondary Analysis of a Cluster Randomized Controlled Trial
Many patients with transient ischemic attack (TIA) receive initial assessments by general practitioners (GPs) who may lack TIA management experience. In a randomized controlled trial (RCT), we showed that electronic decision support for GPs improves patient outcomes and guideline adherence. Some stroke services prefer to improve referrer expertise through TIA/stroke education sessions instead of promoting TIA decision aids or triaging tools. This is a secondary analysis of whether a GP education session influenced TIA management and outcomes. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Annemarei Ranta, Susan Dovey, John Gommans, Murray Tilyard, Mark Weatherall Source Type: research

Paradoxical Association of Symptomatic Local Vasogenic Edema with Global Cerebral Hypoperfusion after Direct Revascularization Surgery for Adult Moyamoya Disease
Superficial temporal artery –middle cerebral artery (STA–MCA) anastomosis is the standard treatment for Moyamoya disease (MMD). Cerebral hyperperfusion syndrome is a potential complication of this procedure and can cause local vasogenic edema and/or delayed intracerebral hemorrhage. Cerebral hypoperfusion is a contradictor y postoperative pathophysiological condition implicated in MMD, but its association with symptomatic local vasogenic edema has not been reported. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2018 Category: Neurology Authors: Ryosuke Tashiro, Miki Fujimura, Shunji Mugikura, Kuniyasu Niizuma, Hidenori Endo, Toshiki Endo, Teiji Tominaga Tags: Case Studies Source Type: research

Masthead
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2018 Category: Neurology Source Type: research

Editorial Board
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2018 Category: Neurology Source Type: research

Table of Contents
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2018 Category: Neurology Source Type: research

Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Hematoma Expansion of Intracerebral Hemorrhage
Hematoma expansion is an independent risk factor of unfavorable outcome after intracerebral hemorrhage (ICH), which always occurs in the early phase after symptoms onset. The relationship between underlying small vessel disease (SVD) and hematoma expansion was inconsistent in patients with ICH. We aimed to investigate the relationship between magnetic resonance (MR) characteristics of SVD and hematoma expansion in patients with ICH within 72 hours after symptoms onset. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2018 Category: Neurology Authors: Yue Suo, Weiqi Chen, Yuesong Pan, Yujing Peng, Hongyi Yan, Wei Li, Gaifen Liu, Yongjun Wang Source Type: research

Estradiol Protects White Matter of Male C57BL6J Mice against Experimental Chronic Cerebral Hypoperfusion
Estradiol is a sex steroid hormone known to protect the brain against damage related to transient and global cerebral ischemia. In the present study, we leverage an experimental murine model of bilateral carotid artery stenosis (BCAS) to examine the putative effects of estradiol therapy on chronic cerebral hypoperfusion. We hypothesize that long-term estradiol therapy protects against white matter injury and declarative memory deficits associated with chronic cerebral hypoperfusion. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2018 Category: Neurology Authors: Reymundo Dominguez, Madison Zitting, Qinghai Liu, Arati Patel, Robin Babadjouni, Drew M. Hodis, Robert H. Chow, William J. Mack Source Type: research

Association between Delirium and Prehospitalization Medication in Poststroke Patients
Medication is an important risk factor for delirium; however, the association between delirium and prehospitalization medication is unclear. We investigated the association between prestroke medication and poststroke delirium. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2018 Category: Neurology Authors: Ryuichiro Hosoya, Yohei Sato, Emika Ishida, Haruna Shibamoto, Seiichi Hino, Hiroaki Yokote, Tomoyuki Kamata Source Type: research

Intracranial Large and Medium Artery Atherosclerotic Disease and Stroke
Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide and is associated with a high risk of stroke recurrence. We sought to perform a literature review of the epidemiology, pathophysiology, and treatment options. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2018 Category: Neurology Authors: Sami Al Kasab, Colin P. Derdeyn, Waldo R. Guerrero, Kaustubh Limaye, Amir Shaban, Harold P. Adams Tags: Review Article Source Type: research

Response to Letter to the Editor Regarding “Yield of Computed Tomography (CT) Angiography in Patients with Acute Headache, Normal Neurological Examination, and Normal Non Contrast CT: A Meta-Analysis.”
Thank you for the interesting letter concerning the outcomes and conclusions of our article “Yield of Computed Tomography (CT) Angiography in Patients with Acute Headache, Normal Neurological Examination and Normal Non Contrast CT: A Meta-Analysis”. We would like to respond and clarify, as some of the uttered concerns are ours as well, as we had already stipulated in our discussion. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2018 Category: Neurology Authors: Imanda M.E. Alons, Ben F.J. Goudsmit, Korne Jellema, Marianne A.A. van Walderveen, Marieke J.H. Wermer, Ale Algra Tags: Letter to the Editor Source Type: research

Thrombosed Aneurysm of the Posterior Inferior Cerebellar Artery and Lateral Medullary Ischemia as the Initial Presentation of Polyarteritis Nodosa: Case Report and Literature Review
A 27-year-old woman with a previously undiagnosed polyarteritis nodosa (PAN) developed lateral medullary stroke related to a thrombosed posterior inferior cerebellar artery (PICA)-origin aneurysm. A concurrent thrombosis of the PICA was identified on high-resolution 3-dimensional CUBE T1 magnetic resonance imaging sequence at 3  T. Body computed tomography angiography, magnetic resonance imaging–magnetic resonance angiography, and digital angiography revealed multiple tiny aneurysms of the visceral arteries and bilateral kidney infarcts. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2018 Category: Neurology Authors: Monique Boukobza, Antoine Dossier, Jean-Pierre Laissy Tags: Case Studies Source Type: research

Estradiol Protects White Matter of Male C57BL6J Mice against Experimental Chronic Cerebral Hypoperfusion
Estradiol is a sex steroid hormone known to protect the brain against damage related to transient and global cerebral ischemia. In the present study, we leverage an experimental murine model of bilateral carotid artery stenosis (BCAS) to examine the putative effects of estradiol therapy on chronic cerebral hypoperfusion. We hypothesize that long-term estradiol therapy protects against white matter injury and declarative memory deficits associated with chronic cerebral hypoperfusion. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2018 Category: Neurology Authors: Reymundo Dominguez, Madison Zitting, Qinghai Liu, Arati Patel, Robin Babadjouni, Drew M. Hodis, Robert H. Chow, William J. Mack Source Type: research

Association between Delirium and Prehospitalization Medication in Poststroke Patients
Medication is an important risk factor for delirium; however, the association between delirium and prehospitalization medication is unclear. We investigated the association between prestroke medication and poststroke delirium. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2018 Category: Neurology Authors: Ryuichiro Hosoya, Yohei Sato, Emika Ishida, Haruna Shibamoto, Seiichi Hino, Hiroaki Yokote, Tomoyuki Kamata Source Type: research