Visual stroke symptom triage tool to reduce delays due to limited English proficiency in Emergency department stroke activations
Limited English proficiency (LEP) may contribute to delays in care and worse outcomes in patients hospitalized with stroke. Limited access to interpreter services leads to delays in triage, code activation, imaging evaluations, and treatment. At our Comprehensive Stroke Center, 20% of patients with stroke have a Chinese dialect as a primary language and LEP. We sought to assess differences in stroke activation process times and IV alteplase treatment (IVT) rates between English and LEP (Chinese dialect) patients before and after implementation of a visual stroke symptom (VSS) triage tool. (Source: Journal of Stroke and Cer...
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Lisa M. Scott Tags: Poster 02 Source Type: research

Racial Disparities in Magnetic Resonance Imaging and Perfusion-Diffusion Mismatch
The central concept of mismatch between perfusion and diffusion targets identified by magnetic resonance imaging offers an approximation of the tissue at risk of infarction if reperfusion is not achieved. This measure is becoming increasingly relevant in determining eligibility for and prognosis following thrombolytic and endovascular treatments, particularly at extended time windows. A few studies have shown that Black stroke patients are more likely to suffer small-vessel ischemic strokes and fewer cardioembolic strokes occluding large vessels. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Benjamin Taylor King Tags: Poster 03 Source Type: research

Racial Disparities in Functional Outcomes after Mechanical Thrombectomy for Acute Ischemic Stroke
Previous studies have shown racial disparities in access to treatment and outcomes in ischemic stroke patients. We set out to describe racial disparities in functional outcomes among ischemic stroke patients receiving mechanical thrombectomy. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Erica Marie Jones Tags: Poster 04 Source Type: research

Impact of Race on Patient Outcomes After Stroke Thrombectomy: Single Center Experience
The effect of race on stroke thrombectomy outcomes is poorly defined. Here we analyzed the influence of race on clinical outcomes following stroke thrombectomy at a single urban comprehensive stroke center. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Helio De Paula Carvalho Tags: Poster 05 Source Type: research

Disparities in healthcare coverage among stroke survivors: Results from a nationally representative data set.
This study sought to investigate determinants of healthcare coverage among stroke survivors. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Daudet Ilunga Tshiswaka Tags: Poster 06 Source Type: research

Health-related quality of life, social support, and social networks in African-American stroke survivors with and without aphasia.
Health-related quality of life (HRQL) provides insight into the impact of a health condition on an individual's ability to lead a fulfilling life. Previous research has identified determinants of HRQL in stroke survivors to include communication, mobility, mental/emotional health, role, and social functioning. However, health disparities among minority populations may influence HRQL in stroke survivors with and without aphasia. The aim of this study was to explore the HRQL and social functioning in a homogenous sample of African-Americans with chronic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Davetrina Seles Gadson Tags: Poster 07 Source Type: research

Traditional Vascular Risk Factors Account for Different Proportions of Ischemic Stroke Within Different Gender and Race Groups
Few studies have compared the proportion of ischemic strokes attributable to traditional vascular risk factors (population-attributable risk percent or PAR%) between genders and races. The PAR% is a function of the population prevalence and strength of association of a risk factor. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Elizabeth Aradine Tags: Poster 08 Source Type: research

Patent Foramen Ovale Closure in hospitalized stroke patients in the United: Is there a racial disparity?
Racial disparity in stroke is well documented. Whether such disparity exists in the frequency of Patent Foramen Ovale (PFO) closure among patients with ischemic stroke (IS) is unclear. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Alain Lekoubou Tags: Poster 09 Source Type: research

Impact of Race-Ethnic and Economic Disparities on Rates of Vascular Dementia in the National Inpatient Sample Database from 2006-2014
We have previously reported regional differences in the rates of vascular dementia (VD) in the United States (US), with the West having lower rates of VD diagnosis found in the Healthcare Cost and Utilization Project Nationwide Inpatient Sample (NIS) Database. We aimed to determine if these regional differences were associated with race-ethnic disparities in economic status or prevalence of the stroke risk factors hypertension, diabetes, and hyperlipidemia. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Alexis Netis Simpkins Tags: Poster 10 Source Type: research

Ethnic Differences in Childhood Moyamoya Presentation and Evolution
Emerging evidence suggests that moyamoya natural history differs based on ethnic background and underlying cause. We sought to compare clinical and radiographic presentation and evolution of moyamoya vasculopathy based on ethnic background. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Matsanga Leyila Kaseka Tags: Poster 11 Source Type: research

Frailty score does not explain differences in mortality between underweight black and white veterans after stroke
Previous studies suggest being underweight may increase risk of mortality after stroke. Paradoxically, in several studies of U.S. Veterans, black stroke patients have better survival compared to whites, even at lower body mass index (BMI). We hypothesized that frailty status may explain the observed differences. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Lauren Elizabeth Costa Tags: Poster 12 Source Type: research

Racial and Ethnic Disparities in Mortality in US Veterans Following an Incident Subarachnoid Hemorrhage
Blacks and Hispanics have been shown to have higher stroke mortality than Whites. However, few studies have investigated health disparities in post-stroke mortality for specific stroke types, such as subarachnoid hemorrhage (SAH). We analyzed risk of mortality by race/ethnicity after incident SAH in a national sample of stroke patients from the Veteran's Health Administration (VHA). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Laura Michelle Tarko Tags: Poster 13 Source Type: research

Hispanics have higher grade intracerebral hemorrhage compared to non-Hispanics
We set out to determine whether Hispanics have worse intracerebral hemorrhage (ICH) as measured by the ICH score. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Jessica Houck Tags: Poster 14 Source Type: research

Cerebral Small Vessel Disease among US minority Survivors of Intracerebral Hemorrhage
Black and Hispanic survivors of Intracerebral Hemorrhage (ICH) are at higher risk of recurrent intracranial bleeding when compared to their white counterparts. While established differences in hypertension severity after ICH play a role, they do not fully account for this health disparity. MRI-based markers of chronic Cerebral Small Vessel Disease (CSVD) are consistently associated with increased risk of recurrent ICH. We therefore sought to investigate whether differences in CSVD subtype and/or severity exist among self-reported race/ethnicity groups. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Juan Pablo Castello Tags: Poster 15 Source Type: research

Hypertension Severity, Race/Ethnicity and Stroke Recurrence Risk among Oldest Old Intracerebral Hemorrhage Survivors
Oldest old (age ≥80 years) survivors of Intracerebral Hemorrhage (ICH) may be at higher risk for stroke recurrence, reflecting increasing hypertension severity with aging. Because minority ICH survivors (African American and Hispanic) are at higher risk of stroke recurrence, oldest-old individuals in these racial /ethnic groups are likely to be at even higher risk. We sought to determine whether: 1) oldest old ICH survivors are at higher risk for stroke recurrence; and 2) minority oldest-old ICH survivors are at even higher risk for recurrent stroke than age-matched white counterparts. (Source: Journal of Stroke and Cer...
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Axana Rodriguez-Torres Tags: Poster 16 Source Type: research

An Evaluation of Racial Differences in the Classification of Blood Pressure Control after Stroke
Blood pressure (BP) control is important for secondary stroke prevention and there are racial differences in BP control after stroke. BP is often treated based on in-clinic BP measurement; however, casual BP obtained in clinic may be inaccurate. We sought to determine whether race was associated with BP control misclassification in stroke survivors. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Saviour Achilike Tags: Poster 17 Source Type: research

D-dimer and the Risk of Incident Hypertension in Black and White Americans
The underlying causes of hypertension remain ill-defined as are the reasons for the increased risk among black Americans. Research suggests D-dimer, a procoagulant marker higher in black Americans, is a risk marker for hypertension. However, these data are mostly cross-sectional, and the impact on racial disparities in hypertension incidence has not been studied. We hypothesized that those with higher D-dimer levels will be at a higher risk of developing incident hypertension, and D-dimer modifies racial differences in hypertension risk. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Debora Kamin Mukaz Tags: Poster 18 Source Type: research

Reach Out: Recruitment in a multicomponent, mobile health, behavioral intervention to reduce blood pressure in the Emergency Department patient population.
Hypertension is the most important modifiable risk factor for cardiovascular disease and an important contributor to the racial disparities of stroke. The Emergency Department (ED) may represent an opportunity to identify difficult-to-reach hypertensive populations. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Candace Odelia Whit Tags: Poster 19 Source Type: research

Masthead
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Source Type: research

Editorial Board
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Source Type: research

Table of Contents
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Source Type: research

Serum Neurofilament Light Chain as a Predictive Biomarker for Ischemic Stroke Outcome: A Systematic Review and Meta-analysis
Despite advances in early diagnosis and aggressive management of vascular risk factors, stroke remains the leading cause of death and long-term disability worldwide, and that ischemic stroke accounts for about 85% of all cerebrovascular diseases.1 Only a third of patients who survive an ischemic stroke recovers with minimal or no deficit, whereas the majority remains moderately or severely disabled lifetime.2 With the increasing of life expectancy and aging of the population, care for poststroke patients has become an important social and economic burden. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2020 Category: Neurology Authors: Daoshen Liu, Jing Chen, Xuanying Wang, Jialun Xin, Ruili Cao, Zhirong Liu Source Type: research

Challenges of Thrombolysis in a Developing Country: Characteristics and Outcomes in Peru
Background: The availability of intravenous tissue plasminogen activator (IV-tPA) remains limited worldwide, especially in low-income countries, where the burden of disability due to ischemic stroke is the highest. Aims: To evaluate outcomes and safety of IV-tPA at the only Peruvian reference institute for neurologic diseases. Methods: We conducted a prospective, observational study of stroke patients who received IV-tPA between 2009 and 2016. We assessed characteristics associated with good outcome (modified Rankine scale 0-2) at 3 months using a multivariate regression model; and factors correlated with clinical improvem...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2020 Category: Neurology Authors: Carlos Abanto, Ana Valencia, Pilar Calle, Danny Barrientos, N éstor Flores, María Novoa, Rosa L. Ecos, Jorge Alonso Ramirez, Angela K. Ulrich, Joseph R. Zunt, David L. Tirschwell, Sarah Wahlster Source Type: research

Tilt-Corrected Region Boundaries May Enhance the Alberta Stroke Program Early Computed Tomography Score for Less Experienced Raters
Background: The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is widely used to quantify early ischemic changes in the anterior circulation but has limited inter-rater reliability. Aims: We investigated whether application of 3-dimensional boundaries outlining the ASPECTS regions improves inter-rater reliability and accuracy. Methods: We included all patients from our DEFUSE 2 database who had a pretreatment noncontrast computed tomography scan (NCCT) of acceptable quality. Six raters (2 neuroradiologists, 2 vascular neurologists, and 2 neurology residents) scored ASPECTS of each NCCT without ( “CT...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2020 Category: Neurology Authors: Collin J. Culbertson, S øren Christensen, Michael Mlynash, Jeremy J. Heit, Christian Federau, Christina Mijalski Sells, Catherine Legault, Addason F.H. McCaslin, Katherine Werbaneth, Gregory W. Albers, Maarten G. Lansberg Source Type: research

Botulinum Toxin Type A for Upper Limb Spasticity in Poststroke Patients: A Meta-analysis of Randomized Controlled Trials
Background and Aim: Botulinum toxin type A is considered to be an effective antispasmodic in recent years. We assess the effectiveness of botulinum toxin type A for the treatment of poststroke spasticity in the upper extremity using a meta-analysis. Methods: We searched several databases including PubMed, Web of Science, Embase, and Cochrane database for relevant studies, up until October 2017. All randomized controlled trials of botulinum toxin type A treat poststroke upper limb spasticity published were included. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2020 Category: Neurology Authors: Shiyu Jia, Yang Liu, Liuyan Shen, Xue Liang, Xiaomin Xu, Youdong Wei Source Type: research

Associations of Antithrombotic Timing and Regimen with Ischemic Stroke and Bleeding Complications in Blunt Cerebrovascular Injury
Blunt carotid injuries and vertebral arterial injuries, collectively referred to as blunt cerebrovascular injuries (BCVIs), are generally rare events but are associated with high mortality rates and long-term health effects.1 The long-term effects of BCVI include loss of both cognition and function, including the ability to perform daily cognitive and mobility activities without assistance, recurrent stroke, and need for extensive rehabilitation.2-6 Blunt cerebrovascular injuries have been reported to occur in 0.1-0.7% of all trauma patients in the United States,7-10 although higher rates ( ∼1-2%) have been reported af...
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2020 Category: Neurology Authors: Daniel Barrera, Erica Sercy, Alessandro Orlando, Charles W. Mains, Robert Madayag, Matthew M. Carrick, Allen Tanner, Mark Lieser, David Acuna, James Yon, David Bar-Or Source Type: research

Endovascular Treatment for Cavernous Carotid Aneurysms: A Systematic Review and Meta-Analysis
Background and purpose: Coiling and flow diversion are established endovascular techniques for treatment of cavernous carotid aneurysms (CCAs). We performed a systematic review of published series on endovascular treatment of CCAs in order to assess the efficacy and safety between coiling and flow diversion. Methods: We conducted a computerized search of PubMed, MEDLINE, and Web of Science electronic databases for reports on endovascular treatment of CCAs from 1990 to 2019. Comparisons were made in complete occlusion rate, improvement of symptoms rate and intraoperative complication rate between coiling and flow diversion....
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2020 Category: Neurology Authors: Yang Sun, Benlin Wan, Qi Li, Tang Li, Ge Huang, Wenchao Zhang, Jianghua Yang, Xiaoguang Tong Source Type: research

Corrigendum to ‘Comparison of Antiplatelet Therapies for Prevention of Patent Foramen Ovale-Associated Stroke’ [Journal of Stroke and Cerebrovascular Diseases, Vol. 29, No. 4 (April), 2020: 104632]
The authors regret the accidental omission of Professor Roine's middle initial and specification of his affiliations as both the University of Turku and Turku University Hospital. The authors would like to apologise for any inconvenience caused. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2020 Category: Neurology Authors: Scott E. Kasner, Bryan Randall, Grethe Andersen, Helle K. Iversen, Risto O. Roine, Christina Sjostrand, John F. Rhodes, Lars S øndergaard, The Gore REDUCE Study Investigators Tags: Corrigendum Source Type: research

Relationship between Hematoma Volume and Motor Impairment in Putaminal Hemorrhage
Purpose: Computed tomography (CT) is used for initial assessment of patients with suspected stroke. Motor outcome prediction using the initial CT image is important for clinical rehabilitation. However, there is inconsistency in the results reported by the few publications on hematoma volume and motor outcomes in patients with putaminal hemorrhage. To clarify the direction of hematoma and relationship between the hematoma volume and motor outcomes in patients with putaminal hemorrhage using an initial CT image, we evaluated the volume of direction of hematoma in 170 patients in the subacute phase after putaminal hemorrhage...
Source: Journal of Stroke and Cerebrovascular Diseases - April 13, 2020 Category: Neurology Authors: Hitoshi Ohnishi, Kotaro Takeda, Makoto Watanabe, Shinichiro Maeshima, Shigeru Sonoda Source Type: research

Prediction of Persistent Impaired Glucose Tolerance in Patients with Minor Ischemic Stroke or Transient Ischemic Attack
Background: Impaired glucose tolerance (IGT) in patients with ischemic stroke can return to normal, reflecting an acute stress response, or persist. Persistent IGT is associated with an increased risk of recurrent stroke, other cardiovascular diseases and unfavorable outcome after stroke. We aim to validate our previously developed model to identify patients at risk of persistent IGT in an independent data set, and, if necessary, update the model. Methods: The validation data set consisted of 239 nondiabetic patients with a minor ischemic stroke or TIA and IGT in the acute phase (2-hour post-load glucose levels between 7.8...
Source: Journal of Stroke and Cerebrovascular Diseases - April 13, 2020 Category: Neurology Authors: Elizabeth Osei, Heleen M. den Hertog, Susanne Fonville, Paul J.A.M. Brouwers, Laus J.M.M. Mulder, Peter J. Koudstaal, Diederik W.J. Dippel, Adrienne A.M. Zandbergen, Hester F. Lingsma Source Type: research

Ischemic Tolerance Evaluated by Computed Tomography Perfusion during Balloon Test Occlusion
In this study, we evaluated the utility of computed tomography (CT) perfusion during BTO to quantify ischemic tolerance for detecting delayed ischemic stroke. Materials and Methods: Forty-one patients who underwent BTO for the internal carotid artery were included. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2020 Category: Neurology Authors: Tomoyoshi Kuribara, Takeshi Mikami, Satoshi Iihoshi, Kei Miyata, Sangnyon Kim, Yuka Kawata, Katsuya Komatsu, Yusuke Kimura, Rei Enatsu, Yukinori Akiyama, Toru Hirano, Nobuhiro Mikuni Source Type: research

Dynamic Cerebral Autoregulation in Preclinical Atherosclerotic Cardiovascular Disease
Objective: The influence of atherosclerotic cardiovascular disease (ASCVD) on cerebral blood flow control is not well known. The aim of this study was to investigate the association between cardiovascular function and dynamic cerebral autoregulation (dCA) in patients with preclinical ASCVD. Methods: A total of 44 participants aged 26-76 years were divided into low- and high-risk groups according to the China assessment of ASCVD risk. The cardiac function was assessed by echocardiography. The beat-to-beat blood pressure and cerebral blood flow velocity were measured at rest. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2020 Category: Neurology Authors: Yumei Liu, Takashi Tarumi, Beibei Liu, Jingzhi Li, Xiaoguang Wu, Nan Zhang, Yang Hua Source Type: research

Stroke Awareness in Patients with Incident Stroke Compared to Patients without Stroke or Ischemic Heart Disease
Background: Stroke awareness is known to influence treatment seeking and risk reduction behavior, but there is limited data from Sri Lanka and South Asia. Aim: To describe stroke awareness in incident stroke patients and to compare with patients without stroke and/or ischemic heart disease (IHD) in a Sri Lankan tertiary-care center. Methods: We studied awareness of stroke in all incident stroke patients admitted to a tertiary-care center in Sri Lanka and compared with a group of age- and sex-matched patients without stroke and/or IHD, over 2 years. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2020 Category: Neurology Authors: Udaya Ranawaka, Chamila Mettananda, Chamila Thilakarathna, Anushka Peiris, Anuradhini Kasturiratna, Yasoma Tilakaratna Source Type: research

Perioperative Stroke and Readmissions Rates in Noncardiac Non-Neurologic Surgery
Background and Aim: Perioperative stroke is a feared and potentially disastrous complication of surgery. Postdischarge care, specifically hospital readmissions, can significantly impact postsurgical recovery and provides a useful metric for quality care. Our primary aim was examining 30-day readmissions for patients who had a perioperative stroke undergoing noncardiac non-neurosurgery. Methods: We analyzed data from the State Inpatient Database, a database of community hospital discharges, in California between 2008 and2011. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 8, 2020 Category: Neurology Authors: Nikita Raman, Khaled Al-Robaidi, Ashutosh Jadhav, Parthasarathy D. Thirumala Source Type: research

Incidence of Hospitalization for Stroke in Queensland, Australia: Younger Adults at Risk
Background: Trends in the incidence of stroke are important for health care planning. Information is particularly scarce in Australia, due to the paucity of studies with access to recent, large-scale, longitudinal datasets. In this paper we investigated the incidence of hospitalization for stroke by sex, age, and subtype in the whole State of Queensland (Australia). Methods: We obtained data of all hospital admissions for stroke in Queensland from 2002 to 2015. Age standardized hospitalization rates for first-ever stroke were calculated along with WHO adjusted rates. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 8, 2020 Category: Neurology Authors: Deanna Anderlini, Guy Wallis, Welber Marinovic Source Type: research

Effectiveness of Home-based rehabilitation in improving physical function of persons with Stroke and other physical disability: A systematic review of randomized controlled trials
A significant number of people with physical disabilities in the world, especially in most developing countries face a lot of impediments. There is a dearth of literature describing the consensus of effectiveness of home-based rehabilitation programs designed specifically for people living with different types of physical disabilities resulting from stroke, Parkinson's and other musculoskeletal conditions. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2020 Category: Neurology Authors: Asmare Yitayeh Gelaw, Balamurugan Janakiraman, Berihu Fisseha Gebremeskel, Hariharasudhan Ravichandran Source Type: research

Tokyo Metropolitan Stroke Emergency Medical Services for Interventional Stroke Treatment: The Tama-REgistry of Acute Thrombectomy (TREAT) Study
It is not clear how patients with large vessel occlusion (LVO) who have undergone mechanical thrombectomy (MT) were transported to hospitals by emergency medical services. Here, we describe the current status of the stroke delivery system in a large city. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 6, 2020 Category: Neurology Authors: Arata Abe, Takahiro Ota, Masayuki Ueda, Tatsuo Amano, Keigo Shigeta, Yuji Matsumaru, Yoshiaki Shiokawa, Teruyuki Hirano Source Type: research

Knowledge, Motivation and Sustainability: Divergent Effects of a Staff Training Program on Residents and Specialists in Acute Stroke Care
Background: To improve the clinical efficiency of acute stroke management, we implemented a new staff training intervention. The training consisted of a case-based discussion of recent thrombolysis cases with the entire neurologic staff for 1 year. Here, we sought to determine whether the effects of this training were sustained after the discontinuation of the intervention. Methods: All thrombolysis cases prior to the intervention (2015, 2016), during the time of training (2017) and after the discontinuation of the training (2018) were recorded and compared. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 4, 2020 Category: Neurology Authors: Caroline C. Klingner, Albrecht G ünther, Stefan Brodoehl, Otto W. Witte, Carsten M. Klingner Source Type: research

Trends in One Month and One Year Hemorrhagic Stroke Case Fatality Rates in the Czech Republic between 1998 and 2015
This retrospective cross-sectional study reports 1 month and 1 year intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) case fatality rates and their temporal trends in the Czech Republic between 1998 and 2015. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 4, 2020 Category: Neurology Authors: Tomas Bryndziar, Petra Sedova, Robert D. Brown, Eva Fiserova, Miroslav Zvolsky, Josef Bednarik, Robert Mikulik Source Type: research

Central Nervous System Fungal Infection-Related Stroke: A Descriptive Study of Mold and Yeast-Associated Ischemic Stroke
We report a single-center retrospective case series of all adult patients who presented with concurrent CNS fungal infection and stroke between 2010 and 2018. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 3, 2020 Category: Neurology Authors: Pravin George, Joanna I. Ramiro, Joao A. Gomes, Christopher R. Newey, Adarsh Bhimraj Source Type: research

Dupilumab for Atopic Dermatitis, a Possible Risk Factor of Juvenile Ischemic Stroke: A Case Report
We report the case of a 20-year-old man with atopic dermatitis treated with dupilumab for half a year, who presented with sudden onset of dizziness, nausea, and slight cerebellar ataxia. Brain magnetic resonance imaging revealed acute infarction in the bicerebellar hemispheres. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 3, 2020 Category: Neurology Authors: Ryo Iwase, Taro Ishiguro, Kyohei Fujita, Satoru Ishibashi, Takanori Yokota Source Type: research

Multiple Cerebral Hemorrhages With Microbleeds in Intravascular Large B-Cell Lymphoma
This is an extremely rare reported case of intravascular large B-cell lymphoma (IVLBCL) presenting with acute hemorrhages and numerous microbleeds. An 80-year-old man presented with consciousness disturbances after convulsion. Computed tomography revealed multiple hemorrhages, and susceptibility-weighted imaging (SWI) demonstrated numerous microbleeds. Brain biopsy showed CD20-positive cells in small vessels; accordingly, IVLBCL was diagnosed. IVLBCL should be considered as a differential diagnosis in multiple cerebral hemorrhages and microbleeds. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2020 Category: Neurology Authors: Masamune Kimura, Satoru Fujiwara, Atsushi Tanaka, Yoshihiro Omura, Daisuke Yamashita, Takuya Hinoda, Nobuyuki Sakai, Nobuo Kohara Tags: Case Report Source Type: research

Acute Psychological Stress is a Trigger for Stroke: A Case-Crossover Study
Conventional risk factors for stroke that have been identified are mostly chronic diseases that explain much of the variation as to who develops stroke. However, these risk factors do not equip us with the means to predict when an event like stroke will occur. It has been observed that acute events like stroke and coronary heart disease are preceded by episodes of acute stress. The present study was undertaken to determine whether acute psychological stress is a potential triggering factor for the occurrence of stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2020 Category: Neurology Authors: Manya Prasad, Pardeep Khanna, V.K. Katyal, Ramesh Verma Source Type: research

Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d
In this study, we explored the neuroprotective effects of miR-219a-5p on brain using an in vitro ischemia model (mouse neuroblastoma N2a cells treated with oxyglucose deprivation and reperfusion), and in vivo cerebral I/R model in mice. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2020 Category: Neurology Authors: Min-Yi Lu, Jin-Rong Wu, Rui-Bing Liang, Yu-Peng Wang, You-Cai Zhu, Zi-Ting Ma, Hao Zhang, Jie Zan, Wen Tan Source Type: research

Augmented Performance Feedback during Robotic Gait Therapy Results in Moderate Intensity Cardiovascular Exercise in Subacute Stroke
Low cardiovascular fitness is common poststroke. Conventional subacute stroke rehabilitation does not meet Australian National Stroke Guidelines for cardiovascular exercise, particularly in mobility-dependent patients. Walking robotics can potentially achieve recommended cardiovascular exercise with these patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2020 Category: Neurology Authors: Nicole Prideaux, Maayken van den Berg, Claire Drummond, Christopher Barr Source Type: research

Rapid Arterial Occlusion Evaluation Scale Agreement between Emergency Medical Services Technicians and Neurologists
Rapid arterial occlusion evaluation (RACE) scale is a valid prehospital tool used to predict large vessel occlusion of major cerebral arteries in patients with suspected acute stroke. RACE scale administered by Emergency medicine services (EMS) technicians in the prehospital setting correlates well with NIH Stroke Scale score after patient arrival at a hospital. Despite this, the RACE scale is often characterized as too difficult for EMS technicians to accurately utilize. There are no data examining RACE scale accuracy in the prehospital setting comparing EMS technicians with neurologists. (Source: Journal of Stroke and Ce...
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2020 Category: Neurology Authors: Christopher T. Hackett, Rahul Rahangdale, Jack Protetch, M. Adeel Saleemi, Sandeep S. Rana, David G. Wright, Robert Fishman, Patty Noah, Ashis H. Tayal Source Type: research

De Novo Renal Artery Stenosis Developed in Initially Normal Renal Arteries during the Long-Term Follow-Up of Patients with Moyamoya Disease
Moyamoya disease is a cerebrovascular disease of unknown origin causing progressive stenosis of the intracranial arteries in the circle of Willis.1,2 Stenoocclusive lesions and the subsequent hemodynamic compromise result in the formation of dilated, fragile collateral vessels at the base of the brain, which are termed moyamoya vessels. The presentation of patients with these lesions varies from asymptomatic to symptoms of headache, epilepsy, and ischemic and hemorrhagic stroke. Patients with moyamoya disease sometimes have concomitant extracranial arterial stenosis3; of all the extracranial arteries reported, the most com...
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2020 Category: Neurology Authors: Shoko Hara, Kazuhide Shimizu, Tadashi Nariai, Mitsuhiro Kishino, Toshifumi Kudo, Tomoyuki Umemoto, Motoki Inaji, Taketoshi Maehara Tags: Case Report Source Type: research

Risk Factors for Poststroke Shoulder Pain: A Systematic Review and Meta-Analysis
Objective: To identify the risk factors identified within 1-month poststroke that predict the onset of poststroke shoulder pain (PSSP) within the first year after stroke. Methods: Five databases (AMED, CINAHL, EMBASE, Medline, and PubMed) were searched from inception to April 2019. Prospective cohort studies that measured a potential risk factor for PSSP within the first month after stroke were included. Two authors independently reviewed and selected articles for inclusion. Risk of bias was assessed using the Quality in Prognosis Studies tool. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2020 Category: Neurology Authors: Richard J. Holmes, Kara J. McManus, Christina Koulouglioti, Beverley Hale Tags: Review Article Source Type: research

A Case of Creutzfeldt-Jakob Disease with Stroke-Like Onset
Creutzfeldt-Jakob disease (CJD) is a prion disease characterized by rapidly progressive dementia that is often followed by behavioral disturbances, ataxia, myoclonus, and akinetic mutism. The initial symptoms of CJD reportedly vary, but the onset is usually gradual. Here, we report a case of CJD with a sudden, stroke-like onset of right hemiparesis to alert readers that CJD can mimic a stroke during its early stage. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2020 Category: Neurology Authors: Kosuke Okamoto, Takato Abe, Yoshiaki Itoh Tags: Case Report Source Type: research

Association between Serum Lipid and Hematoma Expansion after Spontaneous Intracerebral Hemorrhage in Chinese Patients
Intracerebral hemorrhage (ICH) occurs in about 10%-20% of all stroke patients, and the overall incidence is approximately 25 of 100 000 per year1 and is expected to increase, given the increasing age of the population globally. Compared with ischemic stroke, ICH is correlated with a worse outcome, a mortality rate of around 40% and a dearth of effective treatments.1,2 It has been proven that serum lipid plays a vital role in the progression of cardiovascular disease and ischemic stroke.3 Nevertheless, the relationship between serum lipid concentrations and ICH remains unclear. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - March 26, 2020 Category: Neurology Authors: Bin Cai, Lin Peng, Zhi-bin Wang, Mei Zhang, Bin Peng Source Type: research