Preprocedural Neutrophil to Albumin Ratio Predicts In-Stent Restenosis Following Carotid Angioplasty and Stenting
In-stent restenosis (ISR) is unfavorable to the long-term efficacy of carotid angioplasty and stenting (CAS). Inflammation plays a critical role in the development of ISR. The aim of the study was to investigate whether neutrophil to albumin ratio (NAR) is a predictor of ISR in patients undergoing CAS. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2019 Category: Neurology Authors: Huachao Shen, Zhengze Dai, Mengmeng Wang, Shiyuan Gu, Wei Xu, Gelin Xu, Xinfeng Liu Source Type: research

Comparing Outcomes of Patients With Idiopathic Subarachnoid Hemorrhage by Stratifying Perimesencephalic Bleeding Patterns
Background: To determine the clinical outcomes of perimesencephalic subarachnoid hemorrhages based on the computed tomography (CT) bleeding patterns. Methods: This retrospective cohort study included: (1) patients ( ≥18 years) admitted to a comprehensive stroke center (January 2015-May 2018), (2) with angiography-negative, nontraumatic subarachnoid hemorrhage in a perimesencephalic or diffuse bleeding pattern, and (3) had CT imaging performed in less than rqual to 72 hours of symptom onset. Patients were stra tified by location of bleeding on CT: Peri-1: focal prepontine hemorrhage; Peri-2: prepontine with suprasellar c...
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2019 Category: Neurology Authors: Benjamin Atchie, Constance McGraw, Kathryn McCarthy, Rebecca van Vliet, Donald Frei, Alicia Bennett, Russell Bartt, Alessandro Orlando, Jeffrey Wagner, David Bar-Or Source Type: research

Prevalence of Stroke in Fayoum Governorate, Egypt: A Community-Based Study
This study was designed to find out the prevalence of stroke in Fayoum Governorate& to study some associated risk factors. Methods: through this community based cross-sectional study 4784 participants aged more than or equal to 18 years old were enrolled. A multi-stage random sample technique was followed to choose the study sample. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2019 Category: Neurology Authors: Hala A. Shaheen, Wafaa Y. Abdel Wahed, Sharbat T. Hasaneen Source Type: research

Harlequin Syndrome in Acute Thalamic Hemorrhage
We describe a case of Harlequin syndrome with co-existing central first-order Horner syndrome in the setting of a large thalamic hemorrhage with intraventricular extension. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2019 Category: Neurology Authors: Mary Clare McKenna, Poornima Menon, Shane Smyth, Sean Murphy Tags: Case Report Source Type: research

Quality Management Program of Stroke Rehabilitation Using Adherence to Guidelines: A Nationwide Initiative in Japan
In recent years, interest in the quality of medical care has rapidly increased worldwide. However, quality indicators that contribute to establishing standard treatment in stroke medicine, especially rehabilitation, are not well-developed in Japan. Japan has established Kaifukuki (convalescent) rehabilitation wards, and the development of quality indicators for stroke rehabilitation in the convalescent phase is an urgent issue. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2019 Category: Neurology Authors: Seiji Miura, Ryuji Miyata, Shuji Matsumoto, Takahiro Higashi, Yoshinobu Wakisaka, Tetsuro Ago, Takanari Kitazono, Koji Iihara, Megumi Shimodozono Source Type: research

Evaluating the Effect of Comprehensive Intervention on Cerebro-Vascular Function in Population at High Risk of Stroke
Background: Today there exists few intervention researches on cerebro-vascular function in populations at high risk of stroke in China. Methods: Patients more than 40 years old, with at least 1 of stroke risk factors were recruited from outpatient department in 3 hospitals. A quasi-experimental design was performed by assigning participants into 3 groups: comprehensive intervention group, health education group, and control group. Participants in the control group received no intervention but were informed of risk factors of stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 9, 2019 Category: Neurology Authors: Xiangxiang Liu, Yaohua Gu, Yuting Zhang, Yanan Zhang, Xiaodong Tan Source Type: research

Application of Neck Circumference in Four-Variable Screening Tool for Early Prediction of Obstructive Sleep Apnea in Acute Ischemic Stroke Patients
Background: The purpose of this study was to validate and pilot the use of the four-variable screening tool (4V) and modified 4V tools to identify acute ischemic stroke and transient ischemic attack (TIA) patients at high risk of obstructive sleep apnea (OSA). Methods: Two modified scales, 4V-1 (ie, using neck circumference instead body mass index, regardless of gender) and 4V-2 (ie, as above but scored differently according to gender) were designed. These tools were used in a consecutive cohort of 124 acute ischemic stroke/TIA patients, together with the 4V-1, 4V-2, 4V, as well as the STOP-BANG, the Berlin questionnaire, ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 9, 2019 Category: Neurology Authors: Lisan Zhang, Tingting Zeng, Yaxing Gui, Yi Sun, Fei Xie, Dan Zhang, Xingyue Hu Source Type: research

Use of Wearable Technology in Remote Evaluation of Acute Stroke Patients: Feasibility and Reliability of a Google Glass-Based Device
Background: Telestroke is an efficient, cost-effective way to standardize care and improve access to immediate neurologic expertise for rural hospitals and other underserved areas. Hands-free wearable technology potentially allows for faster evaluations that fit easily within prehospital workflows and could improve prehospital triage of stroke patients to appropriate receiving stroke centers. The goal of this study is to assess the feasibility and inter-rater reliability of wearable eyeglass video technology in assessing stroke-related neurologic deficits in patients with suspected acute stroke. (Source: Journal of Stroke ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 9, 2019 Category: Neurology Authors: Ali Reza Noorian, Mersedeh Bahr Hosseini, Gilda Avila, Richard Gerardi, Anne-Fleur Andrle, Michael Su, Sidney Starkman, Jeffrey L. Saver, Latisha K. Sharma Source Type: research

Relationship Between Asymptomatic Intracranial Stenosis and Extracranial Arteriosclerotic Findings in Workplace Health Checkups: A Pilot Study
Background: Intracranial arteriosclerotic disease (ICAD) is common in Asians and has been presumed to be largely associated with metabolic syndrome (MetS), but the risks for asymptomatic ICAD detectable in examinations of the brain, among other tests, are not well known. The present study is aimed at identifying the risks for asymptomatic ICAD using data on risk factors obtained in health checkups, including data from magnetic resonance imaging (MRI), chest computed tomography (CT), and neck echography. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 9, 2019 Category: Neurology Authors: Makoto Shiraishi, Yasuhiro Hasegawa, Nobuyoshi Narita, Hitoshi Miyake Source Type: research

Anterior Cerebral Artery Dissection in a Patient With Autosomal Dominant Polycystic Kidney Disease
Intracranial artery dissection secondary to autosomal dominant polycystic kidney disease is far less common than cerebral aneurysm. A 55-year-old man presented a sudden onset of headache and disturbed consciousness caused by ischemic stroke in the bilateral frontal lobes with minor subarachnoid hemorrhage. The bilateral anterior cerebral arteries were firstly occluded and re-perfused with irregular narrowing and dilation in 3 days after stroke onset, indicating dissection. He was diagnosed with autosomal dominant polycystic kidney disease by abdominal CT findings and by his family history though his renal function was almo...
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2019 Category: Neurology Authors: Makiko Tanaka, Junji Takasugi, Jun Hatate, Nobuko Otsuka, Shiro Sugiura, Taiji Itoh, Tsutomu Takahashi Tags: Case Report Source Type: research

Association Between Silent Brain Infarcts and Cognitive Function: A Systematic Review and Meta-Analysis
Background and Purpose: Silent brain infarct (SBI), which has traditionally been considered clinically silent, has been proposed as a subclinical risk marker for future cognitive function decline. Methods: We conducted a systematic review of literature in the Cochrane Library, MEDLINE, EMBASE, and the China National Knowledge Infrastructure database. Results: In the end, 19 case-control studies, comprising 6712 participants, and 3 prospective cohort studies comprising 4433 participants, met all inclusion criteria and were included in the systematic review. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 5, 2019 Category: Neurology Authors: Chunyan Lei, Qionghua Deng, Haijiang Li, Lianmei Zhong Tags: Review Article Source Type: research

A Narrative Review of Nonvitamin K Antagonist Oral Anticoagulant Use in Secondary Stroke Prevention
The prevalence of atrial fibrillation (AF), the most common cardiac arrhythmia, increases with age, predisposing elderly patients to an increased risk of embolic stroke. With an increasingly aged population the number of people who experience a stroke every year, overall global burden of stroke, and numbers of stroke survivors and related deaths continue to increase. Anticoagulation with vitamin K antagonists (VKAs) reduces the risk of ischemic stroke in patients with AF; however, increased bleeding risk is well documented, particularly in the elderly. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 5, 2019 Category: Neurology Authors: Valeria Caso, Florian Masuhr Tags: Review Article Source Type: research

The Changing Effect of Blood Pressure on Stroke Outcomes Through Acute to Subacute Stage of Ischemic Stroke
This study explored the associations of blood pressure (BP) with various stroke outcomes and investigated their changes by the elapsed time after stroke onset. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2019 Category: Neurology Authors: Jihoon Kang, Beom Joon Kim, Moon-Ku Han, Hee-Joon Bae Source Type: research

Performance Stability and Interrater Reliability of Culturally Adapted 10-Meter Walking Test for Danes with Neurological Disorders
Background: The 10-meter Walking Test (10MWT) is often used to assess people with, e.g., stroke, but often using different procedures. The aims of this study were to translate the 10MWT into Danish, to determine the number of trials needed to achieve performance stability, and to examine the interrater reliability and agreement of the 10MWT in people with neurological disorders. Methods: Translation followed international recommendations, and evaluated in a consecutive sample of 50 people with a neurological disorder. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 4, 2019 Category: Neurology Authors: Christina Weirum Andersen, Morten Tange Kristensen Source Type: research

Effect of Cigarette Smoking on Functional Outcomes in Patients with Spontaneous Intracerebral Hemorrhage
This study aimed to evaluate the relationship between cigarette smoking and outcomes in patients with spontaneous intracerebral hemorrhage (ICH). Methods: This was a retrospective review of consecutive ICH patients enrolled in the ICH Outcomes Project from 2009 to 2017. Patients with age ≥18 years and baseline modified Rankin Scale (mRS) score 0-2 were included. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 3, 2019 Category: Neurology Authors: Natasha Ironside, Ching-Jen Chen, Josephine Pucci, Edward Sander Connolly Source Type: research

ICU Interventions in Ischemic Stroke Patients Treated Using Liberalized IV-tPA Criteria
Background and Objective: Current standard practice guidelines recommend ICU admission for ischemic stroke patients treated with intravenous tissue plasminogen activator (IV-tPA). More recently, the trend in stroke care is to broaden eligibility for IV thrombolysis. Two examples are a more liberal inclusion criteria known as SMART criteria (sIV-tPA), and the transfer of patients to comprehensive stroke centers (CSC). The present study characterizes ICU interventions in these patients. Understanding which stroke patients that require ICU-level care may allow for placement of patients in the appropriate level of care at hosp...
Source: Journal of Stroke and Cerebrovascular Diseases - July 3, 2019 Category: Neurology Authors: Nick M. Murray, Michael Ke, Alan Yee, Charlene Chen, Christine Wong, Ann Bedenk, Julia Fernandes, Nobl Barazangi, David Tong Source Type: research

Response to “Comments on Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage”
I should like to thank Dr. Montaner for the comments on our previously published paper. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 3, 2019 Category: Neurology Authors: Takashi Inoue, Teiji Tominaga Tags: Letter to the Editor Source Type: research

Stroke Volume Predicts Nocturnal Hypoxemia in the Acute Ischemic Stroke after Intravenous Thrombolysis
The Goal: The aim of the study was to investigate whether stroke volume or the presence of ischemic stroke lesion on follow-up computed tomography 1 day after admission had association with sleep apnea among ischemic stroke patients undergoing thrombolysis. Materials and Methods: We prospectively recruited 110 consecutive ischemic stroke patients and performed computed tomography on admission and after 24 hours after intravenous thrombolysis. Stroke volume was measured from post-thrombolysis computed tomography scans. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 2, 2019 Category: Neurology Authors: Jaana K. Huhtakangas, Tarja Saaresranta, Michaela K. Bode, Risto Bloigu, Juha Huhtakangas Source Type: research

Temporal Trends of Sex Differences in Transient Ischemic Attack Incidence Within a Population
Objective: Previously we reported that ischemic stroke incidence is declining over time for men but not women. We sought to describe temporal trends of sex differences in incidence of transient ischemic attack (TIA) within the same large, biracial population. Methods: Among the population of 1.3 million in the Greater Cincinnati Northern Kentucky Stroke Study (GCNKSS) region, TIAs among area residents ( ≥20 years old) were identified at all local hospitals. Out of hospital cases were ascertained using a sampling scheme. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - July 1, 2019 Category: Neurology Authors: Tracy E. Madsen, Jane C. Khoury, Kathleen Alwell, Charles J. Moomaw, Eric Rademacher, Matthew L. Flaherty, Daniel Woo, Felipe De Los Rios La Rosa, Jason Mackey, Sharyl Martini, Simona Ferioli, Opeolu Adeoye, Pooja Khatri, Joseph P. Broderick, Brett M. Kis Source Type: research

Comments on: “Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage”
We have recently read with interest the original article published by Inoue et al1 entitled “Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage.” The authors described the potential use of Lectin-like oxidized Low-Density Lipoprotein Recepor-1 (LOX-1) serum level as a biomarker for intracerebral hemorrhage (ICH). They measure d LOX-1 blood level within first 24 hours after symptoms onset and reported that the biomarker was able to discriminate between ischemic and hemorrhagic strokes (P (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 28, 2019 Category: Neurology Authors: Laura Ramiro, Alba Simats, Anna Penalba, Natalia Gill-Testa, Alejandro Bustamante, Joan Montaner Tags: Letter to the Editor Source Type: research

Stroke Mimics: An Important Source of Bias in Acute Ischemic Stroke Research
We report the characteristics, frequency, and outcomes of stroke mimics treated at our institution. Using our data, we then explore how the inclusion of stroke mimics in stroke outcomes research may be an important source of bias. Methods: We retrospectively identified all patients treated with alteplase in our emergency department from August 2013 to December 2017 for suspected acute ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 28, 2019 Category: Neurology Authors: Ravi Garg, Megan A. Rech, Michael Schneck Source Type: research

Barriers and Facilitators of Stroke Recovery: Perspectives From African Americans With Stroke, Caregivers and Healthcare Professionals
Introduction and Goal: Stroke is a serious health condition that disproportionally affects African-Americans relative to non-Hispanic whites. In the absence of clearly defined reasons for racial disparities in stroke recovery and subsequent stroke outcomes, a critical first step in mitigating poor stroke outcomes is to explore potential barriers and facilitators of poststroke recovery in African-American adults with stroke. The purpose of this study was to qualitatively explore poststroke recovery across the care continuum from the perspective of African-American adults with stroke, caregivers of African-American adults wi...
Source: Journal of Stroke and Cerebrovascular Diseases - June 27, 2019 Category: Neurology Authors: Gayenell S. Magwood, Charles Ellis, Michelle Nichols, Suzanne Perea Burns, Carolyn Jenkins, Michelle Woodbury, Robert Adams Source Type: research

Helicopter Transport for Patients with Cerebral Infarction in Rural Japan
In this study, we evaluated the relationship between helicopter transport and the prognosis of patients with acute cerebral infarction in rural Japan. Methods: This retrospective, observational study included 546 patients with acute cerebral infarction attending Aomori Prefectural Central Hospital, which serves a rural region of Japan. Patients were separated into 2 transport groups: physician-staffed helicopter emergency medical services and ground emergency medical services. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 27, 2019 Category: Neurology Authors: Tatsuya Ueno, Haruo Nishijima, Hiroki Hikichi, Rie Haga, Akira Arai, Chieko Suzuki, Jin-ichi Nunomura, Kyoji Saito, Masahiko Tomiyama Source Type: research

Paradoxical Cerebral Embolism as Initial Manifestation of Chronic Thromboembolic Pulmonary Hypertension: A Case Report
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by chronic thrombi in the pulmonary arteries, causing pulmonary hypertension and right heart failure. Early and accurate diagnosis are essential for successful treatment but are often difficult because clinical signs and symptoms can be nonspecific and risk factors, such as history of venous thromboembolism, may not always be present. Here, we report a case involving a 76-year-old woman who demonstrated paradoxical cerebral embolism as the initial manifestation of CTEPH. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 25, 2019 Category: Neurology Authors: Akira Machida, Itsuki Soejima, Takeshi Bo, Eiichiro Amano, Kiyobumi Ota, Yoshinori Kanno, Tsunekazu Kakuta Tags: Case Report Source Type: research

Letter to the Editor Response
Thank you for your comments. In fact, Healy et al reported an incidence of 10.1% of Atrial High Rate Episodes (AHRE), considering a cut-off of 5 minutes with available electrogram (EGM),1 which is similar to our study (9.3%).2 Paul Ziegler et al did not examine the intracardiac EGM and considered episodes lasting more than 5 minutes. Since EGM was not available, some of these episodes could be false positives results, increasing the incidence of “AHRE” in their study (30%).3 (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2019 Category: Neurology Authors: R. Marinheiro, L. Parreira Tags: Letter to the Editor Source Type: research

Effects of GDNF-Transfected Marrow Stromal Cells on Rats with Intracerebral Hemorrhage
Objective: The present study aimed to investigate the effects of Mesenchymal stem cells/glial cell line derived neurotrophic factor (MSCs/GDNF) transplantation on nerve reconstruction in rats with intracerebral hemorrhage. Methods: GDNF transduction to MSCs was using adenovirus vector pAdEasy-1-pAdTrack-CMV prepared. Intracerebral hemorrhage (ICH) was induced by injection of collagenase and heparin into the caudate putamen. At the third day after a collagenase-induced ICH, adult male SD rats were randomly divided into saline group, MSCs group and MSCs/GDNF group. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2019 Category: Neurology Authors: Li Deng, Xiaoqing Gao, Guangbi Fan, Chaoxian Yang Source Type: research

Association Between Carotid-Cerebral Pulse Wave Velocity and Acute Ischemic Stroke: Clinical Trial Protocol
Pulse wave velocity is commonly regarded as the most effective and noninvasive indicator for evaluating arterial stiffness, while increased arterial stiffness is known to be related to atherosclerosis, which has been proved to play a significant role on the onset of acute ischemic stroke. However, it is still only used in the assessment of central and peripheral arteries. Our previous studies have found that carotid-cerebral pulse wave velocity measured using transcranial Doppler may be a promising method for the assessment of human cerebral arterial stiffness. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2019 Category: Neurology Authors: Xianfan Zeng, Xian Fu, Xuelong Li, Jie Zhou, Shiyan Huang, Xianliang Li, Li Liao, Qingchun Gao Source Type: research

Evaluation of the Intracranial Flow Alteration during Manual Syringe and Continuous Pump Aspiration
While mechanical thrombectomy (MT) has been shown to be effective in the treatment of acute large vessel occlusions, adjunctive measures, such as balloon guide catheters (BGC) and aspiration techniques, are utilized heterogeneously. Clarifying the effects of aspiration applied to the anterior cerebral circulation with proximal flow arrest can shed light on embolic protection during MT. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2019 Category: Neurology Authors: Hideo Okada, Yoshikazu Matsuda, Alex Malisch, Joonho Chung, Daniel M. Heiferman, Demetrius K. Lopes Source Type: research

Postoperative Cerebral Embolism After video-assisted thoracoscopic left upper lobectomy : A Case Report and Literature Review
We present a case of a 55-year-old man without cardiovascular disease history suffering cerebral embolism 2 days after left upper lobectomy. Patient underwent endovascular thrombectomy and discharged hospital 10 days later with proper recovery. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2019 Category: Neurology Authors: Zhu Binbin, Wang Yutao, Zhou Chengwei Tags: Case Report Source Type: research

Effectiveness of Intensive Rehabilitation Therapy on Functional Outcomes After Stroke: A Propensity Score Analysis Based on Japan Rehabilitation Database
This study was a retrospective cohort study. From the database, 6875 patients who were admitted to the convalescent rehabilitation wards with stroke were identified. After excluding 4586 patients, 2325 were eligible for the study. Intensive rehabilitation therapy (IRT) was defined as rehabilitation therapy of more than 15 hours per week by a physical therapist, an occupational therapist, and/or a speech therapist. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2019 Category: Neurology Authors: Tomohiko Kamo, Ryo Momosaki, Keisuke Suzuki, Ryoma Asahi, Masato Azami, Hirofumi Ogihara, Yuusuke Nishida Source Type: research

Intravascular Lymphomatosis Presenting with Spinal Cord Infarction and Recurrent Ischemic Strokes
We report on a 64-year-old man with progressive myelopathy at T6-T7 and recurrent cerebral infarctions. This case is illustrative of the clinical course that is seen in IVL. It aims to present a timeline of imaging findings that demonstrate the progression of disease and characteristic pathology findings. We emphasize the importance of IVL on the differential diagnosis of spinal cord infarction. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2019 Category: Neurology Authors: Stephanie Lyden, Rima M. Dafer Tags: Case Report Source Type: research

High Detection Rate of Atrial Fibrillation With Insertable Cardiac Monitor Implantation in Patients With Cryptogenic Stroke Diagnosed by Magnetic Resonance Imaging
Background: Detection and treatment of atrial fibrillation (AF) is a major goal in preventing secondary stroke. Insertable cardiac monitors (ICMs) are available for diagnosis of arrhythmia monitoring in patients with cryptogenic stroke. Magnetic resonance imaging (MRI)-based diagnostic evaluation for acute ischemic stroke subtype classification is common in Japan and can be useful for specific diagnosis of cryptogenic stroke. Purpose: We aimed to investigate the detection rate of AF with an ICM in patients with cryptogenic stroke who were diagnosed by MRI. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2019 Category: Neurology Authors: Tomonori Iwata, Kenichi Todo, Hiroshi Yamagami, Masafumi Morimoto, Tetsuya Hashimoto, Ryosuke Doijiri, Hiroyuki Furuya Source Type: research

Catastrophic Multiple Microbleeds Caused by Infective Endocarditis Following Intravenous Thrombolysis and Endovascular Thrombectomy
Ischemic stroke is one of the most common complications of infective endocarditis (IE). IE must be considered as one of the causes of acute ischemic stroke (AIS) with emergent large vessel occlusion (ELVO), but early diagnosis of IE is difficult. AIS with ELVO must be treated using endovascular thrombectomy (EVT), with or without intravenous thrombolysis (IVT). IVT for AIS due to IE is not well established and remains controversial because of the risk of intracranial hemorrhage. A 42-year-old man suffered from right hemiparesis and disorientation, and AIS with ELVO was diagnosed. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 20, 2019 Category: Neurology Authors: Ryosuke Maeoka, Ichiro Nakagawa, Hiroyuki Ohnishi, Kenkichi Takahashi, Hiroyuki Nakase, Hideyuki Ohnishi Tags: Case Report Source Type: research

Response to “Letter to the Editor” by Bhattacharyya et al.
We read with great interest the concerns highlighted by Bhattacharyya et al who bring up an important point about the impact of odds ratio (OR) size on the clinical significance. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2019 Category: Neurology Authors: Rakesh Khatri, Mohammad R. Afzal, Mohtashim A. Qureshi, Alberto Maud, Dou Huanyu, Gustavo J. Rodriguez Tags: Letter to the Editor Source Type: research

Meteorological Factors and Seasonal Stroke Rates: A Four-year Comprehensive Study
We report the impact of meteorological variables in extremely hot and arid climate on stroke. Methods: Acute stroke patients admitted from January 2014 to December 2017 were included. The data included demographics, clinical risk factors, temperature, solar radiation, relative humidity, dew point, wind speed, and atmospheric pressure. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2019 Category: Neurology Authors: Abdul Salam, Saadat Kamran, Rubina Bibi, Hesham M. Korashy, Aijaz Parray, Abdulla Al Mannai, Abdulrahman Al Ansari, Krishna Kumar Kanikicharla, Arta Zogaj Gashi, Ashfaq Shuaib Source Type: research

Association Between Cerebral Small Vessel Disease and Central Motor Conduction Time in Patients With Vascular Risk
Background and Purpose: Cerebral small vessel disease (CSVD) is related to motor function disturbance. It includes several types: lacunar infarction, white matter hyperintensity, cerebral microbleeds (CMBs), and enlarged perivascular spaces (EPVS). Transcranial magnetic stimulation (TMS) has been successfully used to evaluate the function of the pyramidal tract. Central motor conduction time (CMCT) is one of the indicators of pyramidal tract dysfunction in motor evoked potential (MEP). The aim of this study was to investigate the association between each type of CSVD and CMCT. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 15, 2019 Category: Neurology Authors: Megumi Kubota, Mutsumi Iijima, Yuka Shirai, Sono Toi, Kazuo Kitagawa Source Type: research

Safety and Efficacy of Reperfusion Therapies for Acute Ischemic Stroke Patients With Active Malignancy
Background and Purpose: Epidemiological correlations between active malignancy (AM) and acute ischemic stroke (AIS) are well-established. However, the effect of reperfusion strategies, particularly mechanical thrombectomy (MT), has been barely investigated in patients with AIS and AM. We aim to evaluate safety and efficacy of reperfusion strategies in such patients. Materials and Methods: We performed a case-control analysis comparing patients with AM and AIS (AM group) to a group of cancer-free patients with AIS (control group). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 14, 2019 Category: Neurology Authors: Fabrizio Sallustio, Alfredo Paolo Mascolo, Federico Marrama, Giacomo Koch, Fana Alemseged, Alessandro Davoli, Valerio Da Ros, Daniele Morosetti, Daniel Konda, Marina Diomedi Source Type: research

Intracranial Artery Calcium Burden Predicts Recurrent Cerebrovascular Events in Transient Ischaemic Attack Patients
Background: Patients with initial transient ischaemic attack (TIA) subsequently have a higher risk of recurrent TIA or acute ischemic stroke (AIS). The role of scoring intracranial arterial calcification (IAC) in predicting the prevalence of stroke remains unclear. We aim to evaluate if radiological CT calcium score measuring IAC burden could predict future ischemic events in a cohort of TIA patients. Methods: We studied consecutive patients from July 2014 to December 2015 who presented with first episode of TIA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 14, 2019 Category: Neurology Authors: Wan Yee Kong, Benjamin YQ Tan, Eide Sterling Ellis, Nicholas JH Ngiam, Wilson GW Goh, Vijay K Sharma, Bernard PL Chan, Leonard LL Yeo Source Type: research

Effects of Exergame on Patients' Balance and Upper Limb Motor Function after Stroke: A Randomized Controlled Trial
This study is a randomized controlled trial. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2019 Category: Neurology Authors: Patr ícia P.B. Henrique, Eliane L. Colussi, Ana C.B. De Marchi Source Type: research

Masthead
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 12, 2019 Category: Neurology Source Type: research

Editorial Board
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 12, 2019 Category: Neurology Source Type: research

Table of Contents
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 12, 2019 Category: Neurology Source Type: research

Cost Effectiveness of Drive and Retrieve System in Hokkaido for Acute Ischemic Stroke Patient Treatment Using Geographic Information System
This study aims to simulate the cost effectiveness of the drive and retrieve system, which can be a method to enhance equality and cost effectiveness of treatments for acute ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 12, 2019 Category: Neurology Authors: Yasuhiro Morii, Toshiya Osanai, Tomoki Ishikawa, Kensuke Fujiwara, Takumi Tanikawa, Kiyohiro Houkin, Eiichi Kobayashi, Katsuhiko Ogasawara Source Type: research

Radiological Eye Deviation as a Predictor of Large Vessel Occlusion in Acute Ischaemic Stroke
This study sought to determine if radiological eye deviation was associated with LVO. Methods: All AIS patients given intravenous thrombolysis who had acute CTA performed in 2 stroke units were reviewed over 2013-2015 for the presence of LVO. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2019 Category: Neurology Authors: Gavin McCluskey, Annemarie Hunter, Elizabeth Best, Jacqueline McKee, Mark O. McCarron, Ferghal McVerry Source Type: research

Tick-borne Encephalitis: Stroke-like Presentation
We report a unique case of clinical symptoms and radiological findings compatible with a stroke-like inflammatory lesion in the thalamus, suggesting microangiopathy from TBEV. Our case shows that TBEV could be a possible cause of stroke-like lesions. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2019 Category: Neurology Authors: Andreas Eleftheriou, Fredrik Lundin, Evangelos Alexandros Petropoulos Tags: Case Report Source Type: research

Japanese Versus Non-Japanese Patients with Transient Ischemic Attack or Minor Stroke: Subanalysis of TIA registry.org
TIAregistry.org is an international cohort of patients with transient ischemic attack (TIA) or minor stroke within 7 days before enrollment in the registry. Main analyses of 1-year follow-up data have been reported.5 We conducted subanalysis on the baseline and 1-year follow-up data of Japanese patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2019 Category: Neurology Authors: Shinichiro Uchiyama, Takao Hoshino, Leila Sissani, Monteiro Tavares Linsay, Kenji Kamiyama, Taizen Nakase, Kazuo Kitagawa, Kazuo Minematsu, Kenichi Todo, Yasushi Okada, Jyoji Nakagawara, Ken Nagata, Hiroshi Yamagami, Takenori Yamaguchi, Pierre Amarenco, T Source Type: research

24-Hour Near-Infrared Spectroscopy Monitoring of Acute Ischaemic Stroke Patients Undergoing Thrombolysis or Thrombectomy: A Pilot Study
Monitoring of acute ischaemic stroke patients during thrombolysis or thrombectomy is based mostly on frequent physical examinations, since no objective measurement of cerebrovascular haemodynamics is available in routine clinical practice. Near-infrared spectroscopy (NIRS) is a bed-side, noninvasive assessment tool that could help monitor these patients and potentially guide therapeutic interventions. Our goal in this pilot study was to investigate whether NIRS is a suitable method to monitor leptomeningeal collateral circulation via changes in cortical oxygen saturation in the first 24 hours of acute ischaemic stroke. (So...
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2019 Category: Neurology Authors: Ádám Annus, András Nagy, László Vécsei, Péter Klivényi Source Type: research

Effects of Candesartan in the Acute Phase of Intracerebral Hemorrhage
Background and Purpose: Uncertainty persists over the effects of blood pressure-lowering treatment in acute intracerebral hemorrhage (ICH). We assessed the effects of treatment with candesartan in acute ICH and according to different types of hematoma. Methods: Post-hoc analysis of the Scandinavian Candesartan Acute Stroke Trial, a randomized- and placebo-controlled, double-masked trial of candesartan in patients with any stroke within the acute phase ( (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2019 Category: Neurology Authors: Mirza Jusufovic, Trude Elisabeth Berge, Rui Guo, Shoujiang You, Candice Delcourt, Craig Anderson, Philip M. Bath, Bj örn W. Karlson, Eivind Berge, Else Charlotte Sandset, Scandinavian Candesartan Acute Stroke Trial (SCAST) Study Group Source Type: research

Electroencephalography Measures are Useful for Identifying Large Acute Ischemic Stroke in the Emergency Department
Background: Early diagnosis of stroke optimizes reperfusion therapies, but behavioral measures have incomplete accuracy. Electroencephalogram (EEG) has high sensitivity for immediately detecting brain ischemia. This pilot study aimed to evaluate feasibility and utility of EEG for identifying patients with a large acute ischemic stroke during Emergency Department (ED) evaluation, as these data might be useful in the prehospital setting. Methods: A 3-minute resting EEG was recorded using a dense-array (256-lead) system in patients with suspected acute stroke arriving at the ED of a US Comprehensive Stroke Center. (Source: Jo...
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2019 Category: Neurology Authors: Lauren Shreve, Arshdeep Kaur, Christopher Vo, Jennifer Wu, Jessica M. Cassidy, Andrew Nguyen, Robert J. Zhou, Thuong B. Tran, Derek Z. Yang, Ariana I. Medizade, Bharath Chakravarthy, Wirachin Hoonpongsimanont, Erik Barton, Wengui Yu, Ramesh Srinivasan, St Source Type: research

Collagen-Induced Platelet Aggregates, Diabetes, and Aspirin Therapy Predict Clinical Outcomes in Acute Ischemic Stroke
This study aimed to identify factors that may affect platelet aggregability and their role in clinical outcomes in acute ischemic stroke. Methods: Consecutive acute ischemic stroke patients (n  = 352) who were transferred within 24 hours after its onset were enrolled. Peripheral venous blood was sampled to measure platelet aggregability and other parameters. Results: Mean values of spontaneous small-sized platelet aggregates and collagen- or adenosine diphosphate (ADP)-induced large-s ized aggregates were elevated in acute ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2019 Category: Neurology Authors: Kaho Harima, Sumika Honda, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Toshiko Tomisawa, Joji Hagii, Hirofumi Metoki, Minoru Yasujima, Tomohiro Osanai Source Type: research