Life Style and Behavioural Factors are Associated with Stroke Recurrence Among Survivors of First Episode of Stroke: A Case Control Study
Secondary stroke prevention treatment is associated with an 80% reduction in risk of recurrent stroke. But one out of every four strokes are recurrent. Adherence to pharmacological therapy and strict control of risk factors are essential for prevention of recurrent strokes. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2021 Category: Neurology Authors: S.D. Shani, R.P. Varma, P.S. Sarma, P.N. Sylaja, V. Raman Kutty Source Type: research

Decision Tree Algorithm Identifies Stroke Patients Likely Discharge Home After Rehabilitation Using Functional and Environmental Predictors
The importance of environmental factors for stroke patients to achieve home discharge was not scientifically proven. There are limited studies on the application of the decision tree algorithm with various functional and environmental variables to identify stroke patients with a high possibility of home discharge. The present study aimed to identify the factors, including functional and environmental factors, affecting home discharge after stroke inpatient rehabilitation using the machine learning method. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2021 Category: Neurology Authors: Takeshi Imura, Yuji Iwamoto, Tetsuji Inagawa, Naoki Imada, Ryo Tanaka, Haruki Toda, Yu Inoue, Hayato Araki, Osamu Araki Source Type: research

Efficacy and Safety of the Telestroke Drip-And-Stay Model: A Systematic Review and Meta-Analysis
To compare outcomes between two models of acute ischemic stroke care. Namely 1) “drip-and-stay”, i.e. IV tissue plasminogen activator (tPA) administered at a spoke hospital in a telestroke network, with the patient remaining at the spoke, versus 2) “drip-and-ship”, i.e. tPA administered at a spoke hospital with subsequent patient transfer to a hub hospital, and 3) “hu b”, i.e. tPA and subsequent treatment at a hub hospital. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - February 2, 2021 Category: Neurology Authors: Hena Waseem, Yasir A. Salih, Charles P. Burney, Mark A. Abel, Natalie Riblet, Anthony Kim, Nathaniel Robbins Source Type: research

Sex Differences in Management and Outcomes of Cardioembolic Stroke: Post HOC Analyses of the RELAXED Study
In this study, we examined sex differences as a post hoc analysis of RELAXED (Recurrent Embolism Lessened by rivaroxaban, an anti-X agent, of Early Dosing for acute IS and TIA with atrial fibrillation) Study. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 30, 2021 Category: Neurology Authors: Takashi Okada, Kazutaka Uchida, Fumihiro Sakakibara, Hiroto Kageyama, Masahiro Yasaka, Kazunori Toyoda, Etsuro Mori, Teruyuki Hirano, Toshimitsu Hamasaki, Hiroshi Yamagami, Takehiko Nagao, Shinichiro Uchiyama, Kazuo Minematsu, Shinichi Yoshimura, for the Source Type: research

Adaptive approach to endovascular management of large vessel occlusion during the COVID-19 pandemic
The COVID-19 pandemic has resulted in unprecedented strain on the health care system. An adaptive strategy for the handling of thrombectomy for patients with large vessel occlusion has evolved at our center to optimize patient care while also minimizing risk of virus transmission. The purpose of this study was to evaluate the effects of the new thrombectomy protocol by comparing thrombectomy times and patient outcomes during the pandemic and pre pandemic period. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2021 Category: Neurology Authors: Borna Ethan Tabibian, Sasha G. Howell, Arsalaan Salehani, Ekaterina Bakradze, Mark Harrigan Source Type: research

Analysis of Mechanical Thrombectomy for Acute Ischemic Stroke on Nights and Weekends Versus Weekdays at Comprehensive Stroke Centers
Treatment of patients outside of normal full-staffing hours has been associated with worse outcomes in multiple medical and surgical conditions [1-4]. Termed the “weekend effect,” such poorer outcomes are presumably due to fewer in-hospital personnel and resources during off-hours [2]. While poorer outcomes have been demonstrated in the treatment of patients presenting with acute ischemic stroke (AIS) on nights/weekends versus weekdays [5-9], the develop ment of comprehensive stroke centers (CSCs) with continuous coverage by stroke neurology, neurointerventional surgery, neurosurgery, and neurocritical care spe...
Source: Journal of Stroke and Cerebrovascular Diseases - January 28, 2021 Category: Neurology Authors: Matthew B. Potts, Ramez N. Abdalla, Pedram Golnari, Madhav Sukumaran, Aaron H. Palmer, Michael C. Hurley, Ali Shaibani, Babak S. Jahromi, Sameer A. Ansari Source Type: research

Negative impact of Interhospital Transfer on Clinical Outcomes of Mechanical Thrombectomy for Fast Progressive Stroke
The time-dependence of the clinical outcome of mechanical thrombectomy is higher in the “fast progressor” in whom cerebral ischemia progresses rapidly. The impact of time-consuming interhospital transfer (IT) on the clinical outcome of such patients is unknown. The effect on clinical outcomes of IT of fast progressors was investigated. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 28, 2021 Category: Neurology Authors: Keigo Shigeta, Takahiro Ota, Junya Kaneko, Katsuya Sato, Rie Aoki, Hiroyuki Jimbo, Yohei Sato, Yoshiaki Kuroshima, Yoshiaki Shiokawa, Teruyuki Hirano, TREAT study group Source Type: research

The Effects of Combining Transcranial Direct Current Stimulation and Gait Training with Functional Electrical Stimulation on Trunk Acceleration During Walking in Patients with Subacute Stroke
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation method that can improve walking function in hemiplegia patients. A meta-analysis of non-invasive brain stimulation demonstrated the beneficial effects of tDCS, such as improving mobility and lower extremity muscle strength in post-stroke patients.1 In particular, applying anodal tDCS over the lower extremity area of the primary motor cortex can significantly improve force steadiness2, as well as motor cortex excitability and function. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 28, 2021 Category: Neurology Authors: Tsubasa Mitsutake, Maiko Sakamoto, Hisato Nakazono, Etsuo Horikawa Source Type: research

The Effects of Unilateral Versus Bilateral Motor Training on Upper Limb Function in Adults with Chronic Stroke: A Systematic Review
Rehabilitation goals for chronic stroke patients are largely focused around regaining functional ability and independence, with particular focus on upper limb motor function. Unilateral and Bilateral motor training may help achieve this. Our objective was to evaluate and compare the effects of unilateral and bilateral motor training on upper limb motor function in chronic stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2021 Category: Neurology Authors: Mark C. Richardson, Craig Tears, Anna Morris, Jenny Alexanders Tags: Review Article Source Type: research

Ameliorative Effects of Combined Revascularization Surgery on Abnormal Collateral Channels in Moyamoya Disease
Abnormal collateral channels, so-called moyamoya vessels, play a critical role to compensate cerebral ischemia, but carry the risk for hemorrhagic stroke in moyamoya disease (MMD). The present study was aimed to clarify if superficial temporal artery to middle cerebral artery (STA-MCA) anastomosis and encephalo-myo-duro-arterio-pericranial synangiosis (EDMAPS) can efficiently regress the abnormal collateral channels in MMD patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2021 Category: Neurology Authors: Shusuke Yamamoto, Daina Kashiwazaki, Haruto Uchino, Hisayasu Saito, Emiko Hori, Naoki Akioka, Naoya Kuwayama, Satoshi Kuroda Source Type: research

Acute Endovascular Revascularization for Patients with Common Carotid Artery Occlusion Apparent on Cervical Magnetic Resonance Angiography
In the endovascular treatment of acute cerebral large-vessel occlusion, cervical magnetic resonance angiography (MRA) is a useful modality for assessing the access route. However, we sometimes encounter cases in which not only the internal carotid artery (ICA), but also the common carotid artery (CCA) is poorly visualized, leading to hesitation over which devices and techniques to choose for revascularization. We retrospectively evaluated such cases, focusing on image findings and treatment results. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2021 Category: Neurology Authors: Hirofumi Asano, Tatsuya Shimizu, Masanori Aihara, Rei Yamaguchi, Kaoru Aishima, Yuhei Yoshimoto Source Type: research

Spinal Cord Infarction in a Patient with Immune Thrombocytopenic Purpura
We report the case of a female patient who developed spinal cord infarction during the exacerbation of her ITP. This case suggests a possible association between spinal cord infarction and ITP, which can cause paradoxical thrombosis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 26, 2021 Category: Neurology Authors: Kenta Orimo, Mizuki Ogura, Keiko Hatano, Naoko Saito-Sato, Hideki Nakayama, Tadao Ishida, Hideji Hashida Tags: Case Report Source Type: research

Response to letter by Dr. Mammi et al.
Rima M. Dafer, Nicholas Osteraas, Jose Biller (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 26, 2021 Category: Neurology Source Type: research

Impact of the COVID-19 pandemic on stroke epidemiology and clinical stroke practice in the US
: To examine the impact of the COVID-19 pandemic on stroke, the number of stroke patients, time since last known well (LKW), morbidity, and mortality of stroke patients in Southwest Healthcare System (SHS), California (CA) and the United States (US) were analyzed during 2019 and compared to 2020. Our hypothesis is that there are regional differences in stroke outcome depending on location during the COVID-19 study period which influences stroke epidemiology and clinical stroke practice. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 26, 2021 Category: Neurology Authors: Daniel Friedlich, Tali Newman, Stephanie Bricker Source Type: research

Prediction of Balance After Inpatient Rehabilitation in Stroke Subjects with Severe Balance Alterations at the Admission
Patients with severe motor alterations would be those on who the prediction of the expected motor response after inpatient rehabilitation programs is most required. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 25, 2021 Category: Neurology Authors: Christian Federico Gath, Matias Gabriel Gianella, Lucas Bonamico, Lisandro Olmos, Maria Julieta Russo Source Type: research

Factors Associated with Level of Physical Activity After Minor Stroke
Health authorities recommend physical activity for general health and to prevent cardiovascular events.1,2 Despite this, physical inactivity is the fourth leading risk factor for global mortality.3 Physical activity has been defined as any bodily movement produced by skeletal muscles that results in energy expenditure, consisting of a broad spectre of daily life activities, including exercise, and resulting in physical fitness.4 There is a dose-response effect of the amount of physical activity on health, where higher volumes, both time and intensity, of activity are associated with additional health benefits. (Source: Jou...
Source: Journal of Stroke and Cerebrovascular Diseases - January 25, 2021 Category: Neurology Authors: Charlotta Hamre, Brynjar Fure, Jorunn L ægdheim Helbostad, Torgeir Bruun Wyller, Hege Ihle-Hansen, Georgios Vlachos, Marie Helene Ursin, Gro Gujord Tangen Source Type: research

Predictive Validity of the Scale for the Assessment and Rating of Ataxia for Medium-Term Functional Status in Acute Ataxic Stroke
This study examines the prognostic validity of the Scale for the Assessment and Rating of Ataxia for patients with acute stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 25, 2021 Category: Neurology Authors: Kota Yamauchi, Kenichi Kumagae, Kei Goto, Risa Hagiwara, Yoshiko Uchida, Eisei Harayama, Shota Tanaka, Sota Kuroyama, Yasuhiro Koyanagi, Shuji Arakawa Source Type: research

Clinical, Laboratory and Ultrasonographic Interrelations in Giant Cell Arteritis
Giant cell arteritis (GCA) is the most common form of systemic vasculitis of medium and large arteries in patients older than 50-years old, causing significant morbidity such as transient or permanent visual loss, aortic aneurysm and stroke.1 (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2021 Category: Neurology Authors: Carolina Soares, Andreia Costa, Rosa Santos, Pedro Abreu, Pedro Castro, Elsa Azevedo Source Type: research

The Independent Association of Prestroke Psychiatric Symptoms and Acute Phase Delirium with Poststroke Mortality at One Year in Nigeria
Undetected acute phase delirium contributes to high poststroke mortality in sub-Saharan Africa (SSA). The present study adds to existing literature by examining the association of prestroke psychiatric symptoms with poststroke mortality at 3 and 12 months in Nigeria. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2021 Category: Neurology Authors: Akin Ojagbemi, Toyin Bello, Mayowa Owolabi, Olusegun Baiyewu Source Type: research

Relationship Between Acute Neurological Function and Long-Term Prognosis in Patients with Large Arterial Occlusions
To clarify the relationship between early neurological symptoms and long-term functional outcomes of acute ischemic stroke, which would be beneficial for patient management and determining clinical study criteria of novel therapeutic interventions. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2021 Category: Neurology Authors: Kotaro Tatebayashi, Shinichi Yoshimura, Nobuyuki Sakai, Kazutaka Uchida, Hiroto Kageyama, Hiroshi Yamagami, Takeshi Morimoto, RESCUE-Japan Registry 2 investigators Source Type: research

A Less Frequent Etiology of Limb Shaking Syndrome: A Severe Middle Cerebral Artery Stenosis
Limb Shaking Syndrome (LSS) is usually associated with internal carotid occlusion. There are few reported-cases in context of middle cerebral artery stenosis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2021 Category: Neurology Authors: Mikel Vicente-Pascual, Gerard Mauri-Capdevila, Francisco Purroy Tags: Case Report Source Type: research

Effect of Dimethyl Fumarate on the Motor Function and Spatial Arrangement of Primary Motor Cortical Neurons in the Sub-Acute Phase of Stroke in a Rat Model
The therapeutic effects of dimethyl fumarate (DMF) in patients with multiple sclerosis and animal models of neurologic disease were reported. The density and the distribution pattern of motor neurons are important in transmitting the signal and controlling the movement-related functions. The present study evaluated the effects of DMF treatment on the neurological functions, infarct volume, and spatial distribution of the neurons in the primary motor cortex after cerebral ischemia. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2021 Category: Neurology Authors: Maryam Owjfard, Mohammad Reza Bigdeli, Anahid Safari, Masoud Haghani, Mohammad Reza Namavar Source Type: research

Reply to: Response to “measuring the optic nerve sheath diameter with ultrasound in acute middle cerebral artery stroke patients”: For application to Long-Duration Spaceflight (LDSF)
We thank Mohanadass and Church for their interest in using Optic Nerve Sheath Diameter (ONSD) measurements in Acute Middle Cerebral Artery (MCA) stroke patients to evaluate the effect of thrombolytic therapy and identify high-risk patients.1 (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2021 Category: Neurology Authors: Seda G üzeldağ, Gökhan Yılmaz Tags: Letter to the Editor Source Type: research

Post Stroke Outcome: Global Insight into Persisting Sequelae Using the Post Stroke Checklist
Following stroke, individuals commonly experience persisting loss of function. Whilst long-term care should involve continued support for ongoing stroke sequelae, this is often not routinely practiced globally. The Post Stroke Checklist was designed to standardise the process of detecting persisting treatable problems following stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2021 Category: Neurology Authors: John Olver, Shanshan Yang, Bianca Fedele, Jun Ni, Judith Frayne, Guangyu Shen, Dean McKenzie Source Type: research

Time to Stable Therapeutic Range on Initiation of Warfarin as an Indicator of Control
Warfarin remains widely used with a time in therapeutic range (TiTR) above 65% recommended for best outcomes. Patients not achieving or maintaining this warfarin control may be better suited to alternate anticoagulants. Despite this, there is limited data defining a suitable trial time in patients initiating warfarin therapy, therefore the aim of this study was to determine the mean time to stable therapeutic range (TtSTR). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2021 Category: Neurology Authors: Narong Puttasung, Andrew K Davey, Tony Badrick, Shailendra Anoopkumar-Dukie, Nijole Bernaitis Source Type: research

Acute Unilateral Masseter Muscle Paralysis Caused by Pontine Infarction
In the present report, we discussed the case of a 57-year-old man with unilateral masticatory muscle weakness, nystagmus, skew deviation and facial hypesthesia due to pontine tegmental infarction. Trigeminal motor neuropathy attributed to brain infarction is very rare. Brain magnetic resonance imaging revealed a small dot-like infarction lesion in the pontine tegmentum. Masticatory muscle weakness was confirmed by an electrophysiological study performed on the day after admission in which there was an incomplete interference pattern without spontaneous denervation activity, suggesting that the patient's masseter muscle wea...
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2021 Category: Neurology Authors: Chonghwee Lee, Taewon Kim Tags: Case Report Source Type: research

Characterizing Blunt Cerebrovascular Injuries and Stroke: A Single Center Retrospective Study
To highlight the occurrence of ischemic stroke after blunt cerebrovascular injuries and discuss the neurologist's role in preventing and managing ischemic strokes in this trauma population. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 20, 2021 Category: Neurology Authors: Lillie Tien, Dan-Victor Giurgiutiu, Erin F. Switzer, Jeffrey A. Switzer Source Type: research

Description of an Association Between Leukocytosis and Clinical Outcomes in Large Hemispheric Infarctions
Large hemispheric infarctions (LHI) are associated with significant morbidity and mortality. Leukocytosis has been observed to directly correlate with stroke severity but has not been specifically described in the LHI population. We hypothesized that patients with LHI and leukocytosis on admission have worse clinical outcomes. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 20, 2021 Category: Neurology Authors: Nandini Abburi, Andrea Sterenstein, Hannah Breit, Sarah Song, Sayona John, Ivan Da Silva, Lauren Koffman Source Type: research

Another ‘BEE’? – Brain-Eye-Ear (BEE) Disease Secondary to HbSC Disease Masquerading as Multiple Sclerosis
We describe a man with hearing loss, visual signs and symptoms, and an accumulating burden of brain lesions, who was treated for a clinical diagnosis of MS for nearly two decades. Genetic testing revealed a unifying diagnosis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 20, 2021 Category: Neurology Authors: Asya Izraelit Wallach, Maria J. Borja, Duan Chen, Rachel Eisenberg, Yasha S. Modi, Cen Zhang, Timothy M. Shepherd, Avindra Nath, Bryan Smith, Jose U. Scher, Catherine Cho, Ilya Kister Tags: Case Report Source Type: research

Response to “Measuring the Optic Nerve Sheath Diameter with Ultrasound in Acute Middle Cerebral Artery Stroke Patients”: For Application to Long-Duration Spaceflight (LDSF)
We thank the authors of the study for their contribution to literature and their insights into the utilisation of optic nerve sheath diameter (ONSD) measurements with regards to therapeutic efficacy of thrombolytic therapy (TT) and identification of complications in populations post-MCA stroke. We would like to introduce the discussion of potential translational benefits of this methodology to the field of long-duration spaceflight (LDSF). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 20, 2021 Category: Neurology Authors: Chloe A. Mohanadass, Lauren E. Church Tags: Letter to the Editor Source Type: research

Reproducible Presyncope Due to Osteophyte Compression Into Transverse Foramen of the C5 Vertebra
Beauty parlor stroke syndrome is characterized by the development of various neurological symptoms during cervical hyperextension, followed by inadequate blood flow through the posterior circulation of the brain. However, there are few reports of beauty parlor stroke syndrome wherein the cause of the posterior circulatory inadequacy has been directly identified. Here we report a case where we could directly detect the origin of the posterior circulatory inadequacy. A 76-year-old Japanese man with hypertension presented with presyncope following cervical retroflexion. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Yuya Kano, Kentaro Yamada, Masahiro Muto, Masahiro Oomura, Noriyuki Matsukawa Tags: Case Report Source Type: research

Occlusive Disease and Upright Activity in Acute Ischemic Stroke
The impact of out-of-bed upright activity on outcomes in ischemic stroke patients with severe extra- and intracranial stenosis or occlusion is unknown. Using ultrasound findings from a cohort recruited to A Very Early Rehabilitation Trial (AVERT) which compared higher dose very early mobilisation (VEM) to usual care (UC), we aimed to explore the association between occlusive disease and 3-month outcomes and occlusive disease-by-mobilisation treatment interactions. Participants with ischemic stroke, with carotid and transcranial Doppler ultrasounds performed ≤1 week after admission, were included in this single centre su...
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Lilian B. Carvalho, Brian Chambers, Karen Borschmann, Tina Kaffenberger, Leonid Churilov, Vincent Thijs, Julie Bernhardt, AVERT trial collaboration group Source Type: research

Association Between Chronic Inflammatory Diseases and Stroke-Associated Pneumonia – An Epidemiological Study
This study assessed the relationship between chronic inflammatory diseases and stroke-associated pneumonia (SAP). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Layne Dylla, Paco S. Herson, Sharon N. Poisson, John D. Rice, Adit A. Ginde Source Type: research

The Joint Association of Septicemia and Cerebrovascular Diseases with In-Hospital MortalityAmong Patients with Left Ventricular Assist Device in the United States
Currently, about 6.2 million adults in the US are reported to have heart failure, and this prevalence is expected to increase by 46% by 2030.1 The prognosis of advanced heart failure especially, advanced systolic heart failure, has improved tremendously with the advent of implantable mechanical circulatory support devices such as left ventricular assist device (LVAD) which is often used as a bridge to heart transplantation or as a destination therapy.2,3 Indeed, LVAD has improved the 1-year survival of patients with advanced heart disease from 52% to about 85%. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Jessica Lovelace, Obadeh Shabaneh, Noah De La Cruz, Damilola R. Owoade, Chike C. Nwabuo, Nandini Nair, Duke Appiah Source Type: research

Cerebral infarction After Laparoscopic Right Lung Wedge or Segment Resection: A Report of Four Cases
Several cases have been reported of patients who experienced cerebral infarction following thoracoscope left lobectomy. Compared with right lung surgery, the pulmonary veins stump after left lobe surgery were longer and thrombosis was more likely. Besides, cases of cerebral infarction after right lung surgery are rarely reported. Left lobectomy is therefore considered as the main risk factor for postoperative cerebral infarction. However, here we report four cases of cerebral infarction after thoracoscopic wedge or segment resection of right lobe, which cause less damage to the pulmonary vein compared with lobectomy. (Sour...
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Fu-Quan Fang, Xian-Hui Kang, Xiao-Hong Wen, Hai-Ying Kong Tags: Case Report Source Type: research

A Triage Model for Interhospital Transfers of Low Risk Intracerebral Hemorrhage Patients
Spontaneous intracerebral hemorrhage (ICH) has an annual incidence of about 30 per 100,000 adults in the US and continues to carry a high morbidity and mortality.1,2 ICH is a dynamic condition with up to one-third of patients having neurologic deterioration after presentation.3,4 Despite paucity of ICH-specific therapies to improve outcomes, some data suggest that management in specialized neurocritical care units reduces mortality.5 Further, the 2015 American Heart Association (AHA) guidelines recommend acute treatment of ICH at tertiary care centers with “neurology, neuroradiology, neurosurgery, and critical care f...
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Safa Kaleem, Michael W. Lutz, Christian E. Hernandez, Jennifer H. Kang, Michael L. James, Keith E. Dombrowski, Christa B. Swisher, Joshua D. VanDerWerf Source Type: research

Predictors of Quality of Life in Stroke Survivors: A 1-year Follow-Up Study of a Tunisian Sample
Stroke survivors often have impaired quality of live (QOL). There is very little information about the determining factors of QOL of stroke survivors in developing countries managed in public health structures with limited access to state of the art treatments. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 15, 2021 Category: Neurology Authors: Soumaya Boudokhane, Houda Migaou, Amine Kalai, Anis Jellad, Ons Borgi, Arwa Bouden, Asma Sriha Belguith, Zohra Ben Salah Frih Source Type: research

Effects of Neck Radiation on Result of Doppler Sonography of Carotid Arteries in Head and Neck Cancer Patients
The aim of this study was to assess the effects of neck radiation on the results of Doppler sonography of carotid arteries in head and neck cancer patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 15, 2021 Category: Neurology Authors: Ali Akhavan, Maryam Farghadani, Hamid Emami, Zahra Naderi Beni, Afsaneh Naderi Beni Source Type: research

Carotid Revascularization Improves Cognition in Patients With Asymptomatic Carotid Artery Stenosis and Cognitive Decline. Greater Improvement in Younger Patients With More Disordered Neuropsychological Performance
In this study the aim was to assess cognitive changes after carotid artery endarterectomy and stenting, using neuropsychological assessment with MoCA and CANTAB test. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 15, 2021 Category: Neurology Authors: Agnieszka Turowicz, Alina Czapiga, Maciej Malinowski, Jaros ław Majcherek, Andrzej Litarski, Dariusz Janczak Source Type: research

Endovascular and Hybrid Interventions for Extracranial Juxta-Skullbase Carotid Artery Aneurysms: Experience and Long-Term Results
Hybrid and endovascular procedures maybe effective and less invasive alternatives to open surgery for treatment of extracranial carotid artery aneurysm (ECAA), but the optimal management of juxta-skullbase ECAA is controversial. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 15, 2021 Category: Neurology Authors: Jie Jin, Yandong Liu, Xu Shen, Jun Bai, Lefeng Qu Source Type: research

IAT-TiMeS: Intra-Arterial Thrombectomy Transfer Metric Study in Texas
We aim to report intra-arterial thrombectomy transfer metrics for ischemic stroke patients that were transferred to hub hospitals for possible intra-arterial thrombectomy in multiple geographic regions throughout the state of Texas and to identify potential barriers and delays in the intra-arterial thrombectomy transfer process. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 15, 2021 Category: Neurology Authors: Tzu-Ching Wu, Christy Ankrom, Michele Joseph, Alyssa Trevino, Liang Zhu, Steven Warach, Roberta R. Novakovic, Mark P. Goldberg, Lee A. Birnbaum, Osman Mir, Gustavo J. Rodriguez, Yazan J. Alderazi, Ameer E. Hassan, Sean I. Savitz Source Type: research

The Utility of the Markers of Coagulation and Hemostatic Activation Profile in the Management of Embolic Strokes of Undetermined Source
Potential causes of embolic stroke of undetermined source (ESUS) include occult malignancy, venous thrombosis (VTE) with paradoxical embolism, and hypercoagulable disorders. Given the association of markers of coagulation and hemostatic activation (MOCHA) with these causes, the objective of this study was to validate the utility of the MOCHA profile in identifying the underlying cause of stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 14, 2021 Category: Neurology Authors: Michael Liu, Deandrea Ellis, Alexander Duncan, Samir Belagaje, Trina Belair, Laura Henriquez, Srikant Rangaraju, Fadi Nahab Source Type: research

Elevated Levels of Inflammation Markers Predict Poor Outcomes in Acute Ischemic Stroke Patients After Intravenous Thrombolysis
Inflammation is associated with the occurrence and prognosis of ischemic stroke. The aim of this study was to evaluate the association between inflammatory biomarkers and the short-term clinical outcomes of acute ischemic stroke (AIS) patients after intravenous thrombolysis (IVT). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2021 Category: Neurology Authors: Dan Hu, Caixia Ding, Xuemei Jiang, Jing Xiao, Chuanyou Li, Lankun Zhang, Tingting Li, Yun Ji, Yuan Peng, Xun Luo, Lei Sheng, Qingmei Wang, Haoxin Wu Source Type: research

Determination of Cerebrovascular Accident Predictors in Patients with New-Onset Atrial Fibrillation After Coronary Artery Bypass Graft Surgery
Postoperative atrial fibrillation (POAF) is associated with an increased risk of short and long-term stroke. Our aim is to identify the independent predictors of cerebrovascular accident (CVA) development in the patients who underwent isolated coronary artery bypass graft (CABG) surgery and developed POAF which lasted within 48  h. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2021 Category: Neurology Authors: Ali Riza Demir, Omer Celik, Begum Uygur, Mustafa Umut Somuncu, Emre Yilmaz, Yalcin Avci, Muhammed Bayram, Mehmet Erturk Source Type: research

Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion
Endovascular thrombectomy (EVT) is highly effective but may also lead to hemorrhagic transformation (HT) and edema, which may be more pronounced in severe ischemia. We sought to determine whether glibenclamide can attenuate HT and edema in a severe ischemia-reperfusion model that reflects EVT. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2021 Category: Neurology Authors: Takahiro Igarashi, Cristina Sastre, Zoe Wolcott, W. Taylor Kimberly Source Type: research

Impact of the Perioperative Blood Pressure on Clinical Outcome after Thrombectomy in Acute Basilar Artery Occlusion
Aim: Optimal blood pressure (BP) management in vertebrobasilar circulation stroke patients undergoing thrombectomy remains undetermined. We  aimed to evaluate the impact of perioperative BP on clinical outcome after MT in acute basilar artery occlusion (BAO) patients. Methods: We retrospectively analyzed all consecutive patients hospitalized with acute basilar artery occlusion administered endovascular treatment within 24 h from Jan uary 2012 to July 2018 in Beijing Tiantan Hospital. BP was measured at regular intervals during the first 24 h after stroke onset, during and after thrombectomy. (Sourc...
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2021 Category: Neurology Authors: Bin Han, Xuan Sun, Raynald Liu, Xu Tong, Baixue Jia, Dapeng Mo, Xiaoqing Li, Gang Luo, Zhongrong Miao Source Type: research

An fMRI, DTI and Neurophysiological Examination of Atypical Organization of Motor Cortex in Ipsilesional Hemisphere Following Post-Stroke Recovery
We report a 61-year-old woman who developed left hemiparesis following a right frontal stroke. She underwent rehabilitation and regained function of the left side of her body. Three years after her first stroke, she developed a large left subdural hematoma and again presented with left hemiparesis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2021 Category: Neurology Authors: Layla Gould, Shaylyn Kress, Josh Neudorf, Katherine Gibb, Amit Persad, Kotoo Meguro, Jonathan Norton, Ron Borowsky Tags: Case Report Source Type: research

Coronavirus Positive Patients Presenting with Stroke-Like Symptoms
Several studies from Wuhan, China have reported neurological manifestations in patients who tested positive for coronavirus disease 2019 (COVID-19). One study reported 214 COVID-19 positive patients, out of which 41.1% had severe infection. 5.7% of patients with severe infection had acute cerebrovascular disease1. Another study looked at 221 COVID-19 positive patients, out of which 5% had ischemic infarcts and 0.5% had cerebral hemorrhage2. A recent study from Mount Sinai Hospital in New York reported five cases of cerebral infarcts due to large vessel occlusion in patients who tested positive for COVID-19. (Source: Journa...
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2021 Category: Neurology Authors: Shaista Alam, Robin N. Dharia, Elan Miller, Fred Rincon, Diana L. Tzeng, Rodney D. Bell Source Type: research

Carotid Endarterectomy is often not Possible after an Unheralded Stroke: Unheralded Stroke in Carotid Artery Stenosis
The ongoing literature recommends carotid endarterectomy (CEA) primarily for patients with neurological symptoms, however CEA can be precluded by the onset of a severe stroke or a total carotid occlusion. The present study aims to evaluate the effect of unheralded strokes in patients with a previously asymptomatic carotid stenosis (ACS) possibly considered for CEA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 8, 2021 Category: Neurology Authors: Rodolfo Pini, Gianluca Faggioli, Antonio Muscari, Cristina Rocchi, Sergio Palermo, Andrea Vacirca, Enrico Gallitto, Mauro Gargiulo Source Type: research

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(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - January 7, 2021 Category: Neurology Source Type: research