Comparison of Premortem Magnetic Resonance Imaging and Postmortem Autopsy Findings of a Cortical Microinfarct
An 85-year-old woman diagnosed with amyotrophic lateral sclerosis died of pneumonia and was autopsied. Magnetic resonance imaging (MRI) performed 16days before death revealed an intracortical high-intensity lesion in her right temporal cortex on three-dimensional (3D)-double inversion recovery (DIR) and 3D-fluid-attenuated inversion recovery (FLAIR) images. Histopathological examination indicated a cortical microinfarct (CMI) juxtaposed to cerebral amyloid angiopathy. Recently, in vivo detection of CMIs using 3D-DIR and 3D-FLAIR on 3-tesla MRI has been reported, and postmortem MRI study confirmed the presence of CMIs. (Sou...
Source: Journal of Stroke and Cerebrovascular Diseases - July 2, 2018 Category: Neurology Authors: Hidehiro Ishikawa, Yuichiro Ii, Atsushi Niwa, Akihiro Shindo, Ai Ito, Keita Matsuura, Ryogen Sasaki, Kenichiro Uno, Masayuki Maeda, Hidekazu Tomimoto Source Type: research

Electroacupuncture Ameliorates Cognitive Impairment and Spontaneous Low-Frequency Brain Activity in Rats with Ischemic Stroke
To evaluate whether electroacupuncture (EA) at Baihui (DU20) and Shenting (DU24) acupoints could improve cognitive function and enhance spontaneous low-frequency brain activity in rats with ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 28, 2018 Category: Neurology Authors: Tao Wen, Xiufeng Zhang, Shengxiang Liang, Zuanfang Li, Xuemei Xing, Weilin Liu, Jing Tao Source Type: research

Delirium in the Acute Phase of Ischemic Stroke: Incidence, Risk Factors, and Effects on Functional Outcome
The aim of this prospective cohort study was to assess the incidence and risk factors of delirium following acute ischemic stroke, as well as its effects on functional outcome. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 28, 2018 Category: Neurology Authors: Jianfeng Qu, Yangkun Chen, Genpei Luo, Huohua Zhong, Weimin Xiao, Hanpeng Yin Source Type: research

Mechanical Thrombectomy: Emerging Technologies and Techniques
The treatment of acute ischemic stroke due to large vessel occlusion (LVO) has revolutionized in the last decade. We sought to compile the most relevant literature published about the evolution in treating this disabling and fatal disease. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 27, 2018 Category: Neurology Authors: Edgar A. Samaniego, Jorge A Roa, Kaustubh Limaye, Harold P. Adams Tags: Review Article Source Type: research

Homocysteine is Associated with Exaggerated Morning Blood Pressure Surge in Patients with Acute Ischemic Stroke
In this study, we aim to investigate the association between Hcy level and ABPM parameters in patients with acute ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 27, 2018 Category: Neurology Authors: Jun-Chao Xie, Ying-Ying Lin, Xiao-Hui Liu, Yi-Chen Zhao, Xiao-Ye Ma, Jia Yu, Xue-Yuan Liu, Yan-Xin Zhao Source Type: research

Endovascular Treatment of Acute Basilar Artery Occlusion: Registro Endovascolare Lombardo Occlusione Basilar Artery (RELOBA) Study Group Experience
Acute basilar artery occlusion (BAO) is considered among the most severe medical emergencies, with very high morbidity and mortality. The aims of this study are to present 5 years experience of 12 centers in Lombardy region on BAO endovascular treatment and to evaluate prognostic factors that may improve clinical outcomes and recanalization rates. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 26, 2018 Category: Neurology Authors: Andrea Giorgianni, Francesco Biraschi, Mariangela Piano, Dikran Mardighian, Roberto Gasparotti, Michele Frigerio, Guglielmo Pero, Luca Quilici, Mario Crispino, Carlo Pellegrino, Marco Pavia, Roberto Peroni, Marco Longoni, Martino Cellerini, Elvis Lafe, Pa Source Type: research

The NAG scale: Noble Predictive Scale for Hematoma Expansion in Intracerebral Hemorrhage
Early hematoma expansion (HE) is not rare in intracerebral hemorrhage (ICH) patients, but detecting those patients with high risk of HE is challenging. The aim of this retrospective study was to investigate the factors associated with HE in acute ICH patients, and to develop a simple predictive scale for HE. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 26, 2018 Category: Neurology Authors: Kenichi Sakuta, Takeo Sato, Teppei Komatsu, Kenichiro Sakai, Yuka Terasawa, Hidetaka Mitsumura, Yasuyuki Iguchi Source Type: research

Secondary Stroke Prophylaxis with Clopidogrel Produces Sufficient Antiplatelet Response
Antiplatelet therapy is a cornerstone prevention strategy for secondary ischemic stroke (IS) and transient ischemic attack (TIA). Yet, a proportion of patients who receive antiplatelet therapy experience recurrent ischemic cerebrovascular events. A recent meta-analysis found an increased risk of recurrent stroke in clopidogrel- or aspirin-treated patients with ischemic stroke who had high on-treatment platelet reactivity (HTPR). Few studies have focused specifically on clopidogrel HTPR. Therefore, the aim of this study was to examine the relationship between clopidogrel HTPR and recurrent ischemic events in a population of...
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2018 Category: Neurology Authors: Charlotte L ützhøft Rath, Niklas Rye Jørgensen, Troels Wienecke Source Type: research

Racial Difference in Cerebral Microbleed Burden Among a Patient Population in the Mid-South United States
Although intracerebral hemorrhage (ICH) is more common among African-Americans, data on the burden of cerebral microbleeds (CMBs) among different races is limited. The purpose of this study is to compare the number, associated factors, and topography of CMBs between African-American and Caucasian populations in the Mid-South United States. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2018 Category: Neurology Authors: Nariman Noorbakhsh-Sabet, Georgios Tsivgoulis, Shima Shahjouei, Yirui Hu, Nitin Goyal, Andrei V. Alexandrov, Ramin Zand Source Type: research

Influence of Contralateral Carotid Occlusion on Outcomes After Carotid Endarterectomy: A Meta-Analysis
There is a controversy about whether the contralateral carotid occlusion (CO) in patients undergoing carotid endarterectomy (CEA) is associated with worse early and long-term outcomes. The aim of this systematic review and meta-analysis was to investigate the impact of CO on outcomes after CEA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2018 Category: Neurology Authors: Wenlong Cheng, Huijun Lu, Yali Hu Source Type: research

The JAGUAR Score Predicts 1-Month Disability/Death in Ischemic Stroke Patient Ineligible for Recanalization Therapy
Most available scoring system to predict outcome after acute ischemic stroke (AIS) were established in Western countries. We aimed to develop a simple prediction score of 1-month severe disability/death after onset in AIS patients ineligible for recanalization therapy based on readily and widely obtainable on-admission clinical, laboratory and radiological examinations in Asian developing countries. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2018 Category: Neurology Authors: Aryandhito Widhi Nugroho, Hisatomi Arima, Naoyuki Takashima, Takako Fujii, Satoshi Shitara, Naomi Miyamatsu, Yoshihisa Sugimoto, Satoru Nagata, Masaru Komori, Yoshikuni Kita, Katsuyuki Miura, Kazuhiko Nozaki Source Type: research

Association of Urinary Incontinence with Cognition, Transfers and Discharge Destination in Acute Stroke Inpatient Rehabilitation
Acute-stroke prognostic indicators remain controversial including relationship of urinary incontinence with outcomes in cognition, transfers, and discharge destination. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2018 Category: Neurology Authors: David S. Kushner, Doug Johnson-Greene Source Type: research

Arterial Stiffness is Independently Associated with Severity of Carotid Siphon Calcifications in Community-Dwelling Older Adults: The Atahualpa Project
Knowledge on the association between arterial stiffness and intracranial atherosclerosis is limited. Here, we aimed to assess whether the aortic pulse wave velocity (PWV) —used as a surrogate of arterial stiffness—might independently predict severity of carotid siphon calcifications (CSCs), used as a marker of atherosclerosis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 19, 2018 Category: Neurology Authors: Oscar H. Del Brutto, Robertino M. Mera, Aldo F. Costa, Ernesto Pe ñaherrera, Rubén Peñaherrera, Mauricio Zambrano Source Type: research

Coil Embolization through Collateral Pathway for Ruptured Vertebral Artery Dissecting Aneurysm with Bilateral Vertebral Artery Occlusion
Intracranial vertebral artery dissecting aneurysm (VADA) is a well-known cause of subarachnoid hemorrhage (SAH). Endovascular treatment is now well established as an effective method for treating ruptured VADA, especially in the acute phase of SAH.1,2 Although stent technology has introduced a new strategy in the treatment of VADA, internal trapping of both the affected vertebral artery (VA) and the VADA using detachable coils is still the standard endovascular treatment for the acute phase of ruptured VADAs to prevent re-rupture. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 15, 2018 Category: Neurology Authors: Satoshi Murai, Kenji Sugiu, Tomohito Hishikawa, Masafumi Hiramatsu, Shingo Nishihiro, Naoya Kidani, Yu Takahashi, Isao Date Tags: Case Studies Source Type: research

A Case for Telestroke in Military Medicine: A Retrospective Analysis of Stroke Cost and Outcomes in U.S. Military Health-Care System
This study illustrates the outcome and cost differences between neurology and primary care ischemic stroke admissions to demonstrate a need for telestroke networks within the Military Health System (MHS). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2018 Category: Neurology Authors: Ajal Dave, Kendra Cagniart, Matthew D. Holtkamp Source Type: research

Nonaneurysmal “Pseudo-Subarachnoid Hemorrhage” Computed Tomography Patterns: Challenges in an Acute Decision-Making Heuristics
Acute aneurysmal subarachnoid hemorrhage (SAH) is a medical and neurosurgical emergency from ruptured brain aneurysm. Aneurysmal SAH is identified on brain computed tomography (CT) as increased density of basal cisterns and subarachnoid spaces from acute blood products. Aneurysmal SAH-like pattern on CT appears as an optical illusion effect of hypodense brain parenchyma and/or hyperdense surrounding cerebral cisterns and blood vessels termed as “pseudo-subarachnoid hemorrhage” (pseudo-SAH). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 5, 2018 Category: Neurology Authors: Tasneem F. Hasan, Walter Duarte, Oluwaseun O. Akinduro, Eric D. Goldstein, Rebecca Hurst, Neil Haranhalli, David A. Miller, Robert E. Wharen, Rabih G. Tawk, William D. Freeman Source Type: research

Computerized Training in Poststroke Aphasia: What About the Long-Term Effects? A Randomized Clinical Trial
Poststroke aphasia is a very disabling disorder, which may affect speech expression, comprehension, and reading or writing. Treatment of aphasia should be initiated as soon as possible after the brain injury; however, the improvement of language functions can occur also in the chronic phase. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2018 Category: Neurology Authors: Rosaria De Luca, Bianca Aragona, Simona Leonardi, Michele Torrisi, Bruno Galletti, Franco Galletti, Maria Accorinti, Placido Bramanti, Maria Cristina De Cola Mstat, Rocco Salvatore Calabr ò Source Type: research

Tele-Rehabilitation after Stroke: An Updated Systematic Review of the Literature
Tele-rehabilitation for stroke survivors has emerged as a promising intervention for remotely supervised administration of physical, occupational, speech, and other forms of therapies aimed at improving motor, cognitive, and neuropsychiatric deficits from stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2018 Category: Neurology Authors: Fred S. Sarfo, Uladzislau Ulasavets, Ohene K. Opare-Sem, Bruce Ovbiagele Tags: Review Article Source Type: research

New Prediction Score for Hematoma Expansion and Neurological Deterioration after Spontaneous Intracerebral Hemorrhage: A Hospital-Based Retrospective Cohort Study
To ensure hematoma expansion and neurological deterioration in the management of acute spontaneous intracerebral hemorrhage, accurate prediction is crucial for initial assessment on admission. We conducted this study to develop a new clinical prediction score using only noncontrast computed tomography image and simply measurable variables. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2018 Category: Neurology Authors: Makiko Miyahara, Ryuichi Noda, Shoji Yamaguchi, Yuta Tamai, Masato Inoue, Kouichiro Okamoto, Tetsuo Hara Source Type: research

Conjugate Eye Deviation Caused by Upper Medial Medullary Infarction: A Case Report
Conjugate eye deviation (CED) is defined as a sustained shift in horizontal gaze toward 1 side, together with gaze failure to the other side, caused by lesions in the brainstem, basal ganglia, or cortical frontal eye fields. To date, very few reports have described CED in patients with medullary infarction. A 76-year-old woman presented with sudden onset of vertigo and right hemiparesis, accompanied by CED to the right with gaze palsy to the left. Her brain magnetic resonance imaging showed left upper medial medullary infarction involving the left nucleus prepositus hypoglossi (NPH) and adjacent to the left inferior olivar...
Source: Journal of Stroke and Cerebrovascular Diseases - May 31, 2018 Category: Neurology Authors: Takashi Ogawa, Yuji Ueno, Hikaru Kamo, Nobukazu Miyamoto, Kazuo Yamashiro, Ryota Tanaka, Yasushi Shimo, Nobutaka Hattori Tags: Case Studies Source Type: research

Infratentorial Cerebral Microbleeds in Patients with Cerebral Amyloid Angiopathy
Cerebral microbleeds (CMBs) observed in hypertension-related arteriolosclerosis tend to occur in the supratentorial deep gray matter, whereas those in cerebral amyloid angiopathy (CAA) typically show a supratentorial lobar distribution. Recently, superficial spontaneous cerebellar intracerebral hemorrhage has been shown to be associated with strictly lobar CMBs. Few data exist on infratentorial CMBs in CAA. The purpose of this study was to describe the incidence, number, and characteristics of infratentorial CMBs in patients with CAA. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 31, 2018 Category: Neurology Authors: Dimitri Renard, Lavinia Tatu, Eric Thouvenot Source Type: research

A Case of Posterior Circulation Ischemic Stroke Caused by Heparin-Induced Thrombocytopenia after Detaining Hepatic Arterial Infusion Catheter
In Japan, hepatic arterial infusion chemotherapy (HAIC) using reservoir system is recommended for patients with hepatocellular carcinoma (HCC) whose hepatic spare ability is favorable. Arterial infusion catheter is commonly detained in hepatic artery via femoral or brachial artery. In our hospital, catheter is often inserted by puncturing the left subclavian or brachial artery considering the patient's activities of daily living (ADL) during long-term detaining. However, it rarely causes posterior circulation ischemic stroke because of the left vertebral artery branches on the path of catheter. (Source: Journal of Stroke a...
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2018 Category: Neurology Authors: Koji Hirashita, Atsushi Matsumoto, Satoru Yabuno, Takahiro Kanda, Masatoshi Yunoki, Kimihiro Yoshino Tags: Case Studies Source Type: research

Rate of Stroke Onset While Driving and Subsequent Collision
Road traffic injury is a major public health problem, with 1.3 million people dying annually in road accidents worldwide.1 Rates of death from road injury have also increased over the last 2 decades, and this trend appears to be continuing.2 The World Health Organization has therefore published a global plan to stabilize and to reduce the forecast level of road traffic fatalities around the world by 2020.1 Recently, there have been a number of vehicle collisions resulting from drivers' health problems. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2018 Category: Neurology Authors: Takuya Inoue, Masahito Hitosugi, Hideki Ooba, Itaru Takehara Tags: Letter to the Editor Source Type: research

Clinical Risk Factors in Thrombolysis therapy: Telestroke Versus Nontelestroke
The objective of this study is to determine clinical risk factors associated with exclusion from thrombolysis in telestroke and nontelestroke settings. These risk factors may offer clues for optimization of thrombolysis therapy in acute ischemic stroke population. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2018 Category: Neurology Authors: Thomas I. Nathaniel, Jordan Gainey, Brice Blum, Chelsea Montgomery, Lowther Ervin, Lee Madeline Source Type: research

Can the Amount of Interventions during the Convalescent Phase Predict the Achievement of Independence in Activities of Daily Living in Patients with Stroke? A Retrospective Cohort Study
This study aimed to evaluate the diagnostic performance of the amount of physical, occupational, and speech therapy intervention and optimal timing necessary for activities of daily living (ADL) independence in patients with stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 29, 2018 Category: Neurology Authors: Takuya Umehara, Ryo Tanaka, Miwako Tsunematsu, Katsunori Sugihara, Yasuyuki Moriuchi, Kaori Yata, Kurumi Muranaka, Junko Inoue, Tatsuo Kohriyama, Masayuki Kakehashi Source Type: research

Postapproval Community Hospital Experience in the United States with Left Atrial Appendage Closure Device (Watchman)
To review the procedural safety and postimplantation complications of Watchman device implanted at 2 community hospitals for primary prevention of systemic embolization in patients with nonvalvular atrial fibrillation (NVAF) who were not candidates for long-term oral anticoagulation (OAC). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 29, 2018 Category: Neurology Authors: Koroush Khalighi, Munish Sharma, Rohit Masih, Vadim Levin Source Type: research

Masthead
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2018 Category: Neurology Source Type: research

Editorial Board
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2018 Category: Neurology Source Type: research

Table of Contents
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2018 Category: Neurology Source Type: research

Intravenous Thrombolysis in Patients with Acute Ischemic Stroke after a Reversal of Dabigatran Anticoagulation with Idarucizumab: A Real-World Clinical Experience
Intravenous thrombolysis (IVT) is contraindicated in patients with acute ischemic stroke (AIS) using oral anticoagulants. A specific human monoclonal antibody was introduced to reverse immediately the anticoagulation effect of the direct inhibitor of thrombin, dabigatran. Until now, mostly individual cases presenting with successful IVT after a reversal of dabigatran anticoagulation in patients with AIS were published. Thus, we aimed to report real-world data from clinical practice. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2018 Category: Neurology Authors: Daniel Šaňák, Stanislava Jakubíček, David Černík, Roman Herzig, Zdeněk Kunáš, Robert Mikulík, Svatopluk Ostrý, Michal Reif, Vladimír Rohan, Aleš Tomek, Tomáš Veverka Source Type: research

Patent Foramen Ovale Closure in the Setting of Cryptogenic Stroke: A Meta-Analysis of Five Randomized Trials
The clinical benefit of patent foramen ovale (PFO) closure after cryptogenic stroke has been a topic of debate for decades. Recently, 3 randomized controlled trials of PFO closure in patients with cryptogenic stroke demonstrated a significantly reduced risk of recurrent stroke compared with standard medical therapy alone. This meta-analysis was performed to clarify the efficacy of PFO closure for future stroke prevention in this population. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 24, 2018 Category: Neurology Authors: Lohit Garg, Affan Haleem, Shweta Varade, Keithan Sivakumar, Mahek Shah, Brijesh Patel, Manyoo Agarwal, Sahil Agrawal, Megan Leary, Bryan Kluck Source Type: research

Stroke Literacy in a South Brazilian City: A Community Based Survey
This community-based and cross-sectional study was performed in a Brazilian city and aimed to evaluate stroke literacy. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 24, 2018 Category: Neurology Authors: Jamir Pitton Rissardo, Ana Let ícia Fornari Caprara, Ana Lucia Cervi Prado Source Type: research

Bilateral Caudate Nucleus Infarctions Following Upper Gastrointestinal Bleeding
A 75-year-old woman presented with consciousness disturbance accompanied by hematemesis. Brain imaging revealed ischemia in the bilateral caudate nuclei and right cerebral watershed area due to stenosis of the right anterior cerebral artery (ACA) and bilateral internal carotid arteries (ICA), and hypoperfusion in the right caudate nucleus. The patient's only symptom was abulia, which gradually resolved. Further brain scans showed that the ICA stenosis had improved, although the right ACA stenosis persisted. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 24, 2018 Category: Neurology Authors: Kensuke Daida, Nobukazu Miyamoto, Hiromi Takagi, Yuji Ueno, Kazuo Yamashiro, Ryota Tanaka, Nobutaka Hattori Tags: Case Studies Source Type: research

Neovascularization in Vertebral Artery Atheroma —A Dynamic Contrast-Enhanced Magnetic Resonance Imaging-Based Comparative Study in Patients with Symptomatic and Asymptomatic Carotid Artery Disease
This study aimed to explore the systemic nature of atherosclerosis by assessing difference in severity of neovascularization as quantified by DCE-MRI of vertebral arteries (VAs) between patients with symptomatic and asymptomatic carotid artery disease. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 24, 2018 Category: Neurology Authors: Ammara Usman, Jianmin Yuan, Andrew J. Patterson, Martin J. Graves, Kevin Varty, Umar Sadat, Jonathan H. Gillard Source Type: research

Volumetric Distribution of the White Matter Hyper-Intensities in Subject with Mild to Severe Carotid Artery Stenosis: Does the Side Play a Role?
The purpose of this paper was to assess the difference in the distribution of white matter hyperintensities (WMHs) on left and right sides of the brain hemispheres of subjects with mild to severe carotid artery stenosis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2018 Category: Neurology Authors: Luca Saba, Pierleone Lucatelli, Michele Anzidei, Michele di Martino, Jasjit S. Suri, Roberto Montisci Source Type: research

Neuroprotective Effects of Tocovid Pretreatment in a Mouse Stroke Model
Tocovid is a new combination of tocotrienols and tocopherol, both of which are neuroprotective agents for preventing cerebral infarction in mice. However, the effects of tocovid on anti-inflammation in ischemic model remain elusive. In the present study, we assessed the effects of Tocovid pretreatment on anti-inflammatory effects after transient middle cerebral occlusion (tMCAO) in mice. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2018 Category: Neurology Authors: Yang Jiao, Jingwei Shang, Yasuyuki Ohta, Hongjing Yan, Xia Liu, Xianghong Li, Ryuta Morihara, Yumiko Nakano, Yusuke Fukui, Xiaowen Shi, Yong Huang, Tian Feng, Mami Takemoto, Kota Sato, Nozomi Hishikawa, Toru Yamashita, Koji Abe Source Type: research

Detection of Subclinical Atherosclerosis in Subclavian Arteries of Subjects with Vascular Risk Factors and Normal Carotid Ultrasound
Most risk scores that use imaging methods to determine the presence of subclinical atherosclerosis assess the carotid and coronary arteries. The value of assessing subclavian arteries to improve the predictive capacity of traditional imaging studies is not known. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2018 Category: Neurology Authors: Federico Rodr íguez Lucci, Elena Schvartz, Roberto Lagos, Lucia Fernández Cisneros, Virginia Pujol Lereis, Sebastian F. Ameriso Source Type: research

Cognitive Impairment, Vulnerability, and Mortality Post Ischemic Stroke: A Five-Year Follow-Up of the Action on Secondary Prevention Interventions and Rehabilitation in Stroke (ASPIRE-S) Cohort
The aim of this study was to examine predictors of mortality in patients 5 years after ischemic stroke, focusing on cognitive impairment, vulnerability, and vascular risk factors assessed at 6 months post stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2018 Category: Neurology Authors: Eva Gaynor, Daniela Rohde, Margaret Large, Lisa Mellon, Patricia Hall, Linda Brewer, Orla Conway, Anne Hickey, Kathleen Bennett, Eamon Dolan, Elizabeth Callaly, David Williams Source Type: research

Association of Short- and Medium-Term Particulate Matter Exposure with Risk of Mortality after Spontaneous Intracerebral Hemorrhage
We investigated the association of short- and medium-term particulate matter (PM) exposure with risk of mortality in patients with spontaneous intracerebral hemorrhage (ICH) identified according to strict etiologic criteria. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2018 Category: Neurology Authors: Stefano Forlivesi, Gianni Turcato, Cecilia Zivelonghi, Massimo Zannoni, Giorgio Ricci, Gianfranco Cervellin, Giuseppe Lippi, Paolo Bovi, Bruno Bonetti, Manuel Cappellari Source Type: research

Association between Homocysteine and Cerebral Small Vessel Disease: A Meta-Analysis
This study aimed to evaluate whether elevated homocysteine levels is associated with risk of different subtypes of cerebral small vessel disease (CSVD) by using meta-analysis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2018 Category: Neurology Authors: Xiangyu Piao, Guangyao Wu, Pei Yang, Jing Shen, Ailing De, Jianlin Wu, Qiumin Qu Source Type: research

Rehabilitation Characteristics in High-Performance Hospitals after Acute Stroke
Rehabilitation characteristics in high-performance hospitals after acute stroke are not clarified. This retrospective observational study aimed to clarify the characteristics of high-performance hospitals in acute stroke rehabilitation. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2018 Category: Neurology Authors: Masashi Sawabe, Ryo Momosaki, Kiyotaka Hasebe, Akira Sawaguchi, Seiji Kasuga, Daichi Asanuma, Shoya Suzuki, Narimi Miyauchi, Masahiro Abo Source Type: research

Modification of Cerebellar Afferent Pathway in the Subacute Phase of Stroke
This study aims to identify the relationship between corticopontocerebellar tract (CPCT) and corticospinal tract (CST) integrity as well as motor function after stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2018 Category: Neurology Authors: Youngkook Kim, Se-Hong Kim, Joon-Sung Kim, Bo Young Hong Source Type: research

Blood Pressure Management after Mechanical Thrombectomy for Acute Ischemic Stroke: A Survey of the StrokeNet Sites
It is unclear what factors providers take into account to determine the target blood pressure (BP) after mechanical thrombectomy (MT) in patients who had acute ischemic stroke. We aimed to understand practice patterns of post-MT BP management across institutions in the United States. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2018 Category: Neurology Authors: Eva A. Mistry, Stephan A. Mayer, Pooja Khatri Source Type: research

Therapeutic Effects of Pretreatment with Tocovid on Oxidative Stress in Postischemic Mice Brain
Dietary supplement is an attempt to reduce the risk of ischemic stroke in high-risk population. A new mixed vitamin E-Tocovid that mainly contains tocotrienols other than tocopherol, attenuated the progression of white matter lesions by oral in humans. However, the effect of Tocovid on ischemic stroke has not been examined. In the present study, we assessed the therapeutic effects of Tocovid pretreatment on transient middle cerebral artery occlusion (tMCAO) in mice. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2018 Category: Neurology Authors: Jingwei Shang, Hongjing Yan, Yang Jiao, Yasuyuki Ohta, Xia Liu, Xianghong Li, Ryuta Morihara, Yumiko Nakano, Yusuke Fukui, Xiaowen Shi, Yong Huang, Tian Feng, Mami Takemoto, Kota Sato, Nozomi Hishikawa, Toru Yamashita, Koji Abe Source Type: research

Post-stroke Movement Disorders: The Clinical, Neuroanatomic, and Demographic Portrait of 284 Published Cases
Abnormal movements are a relatively uncommon complication of strokes. Besides the known correlation between stroke location and certain movement disorders, there remain uncertainties about the collective effects of age and stroke mechanism on phenomenology, onset latency, and outcome of abnormal movements. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2018 Category: Neurology Authors: Ritika Suri, Federico Rodriguez-Porcel, Kelly Donohue, Erin Jesse, Lilia Lovera, Alok Kumar Dwivedi, Alberto J. Espay Source Type: research

Associated with Ischemic Stroke Risk Reduction after Endoscopic Thoracic Sympathectomy for Palmar Sweating
Endoscopic thoracic sympathectomy (ETS) was performed to cure palmar hyperhidrosis (PH). After ETS, blood pressure decreased, and cerebral flow velocity increased within 1 month. However, no studies distinguish between subsequent ischemic and hemorrhagic stroke following ETS for PH. The association between stroke type and PH after ETS must be evaluated. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2018 Category: Neurology Authors: Chun-Gu Cheng, Chun-An Cheng, Wu-Chien Chien, Chi-Hsiang Chung, Jiunn-Tay Lee Source Type: research

Acute Stroke Patients with Newly Diagnosed Diabetes Mellitus Have Poorer Outcomes than Those with Previously Diagnosed Diabetes Mellitus
This study aims to determine the prevalence of NDDM in the ASPs and to compare the outcome in NDDM and previously diagnosed DM (PDDM) in Cameroon. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2018 Category: Neurology Authors: Yacouba Njankouo Mapoure, Hamadou Ba, Chia Mark Ayeah, Caroline Kenmegne, Henry Namme Luma, Alfred Kongnyu Njamnshi Source Type: research

Telestroke Adoption Among Community Hospitals in North Carolina: A Cross-Sectional Study
This study identifies community and hospital characteristics associated with adoption of telestroke among acute care hospitals in North Carolina (NC). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2018 Category: Neurology Authors: Christopher M. Shea, Amir Alishahi Tabriz, Kea Turner, Steve North, Kristin L. Reiter Source Type: research

Gender Gap and Risk Factors for Poor Stroke Outcomes: A Single Hospital-Based Prospective Cohort Study
This study intended to investigate whether etiological stroke subtypes and their corresponding major risk factors have differential effects on outcomes between genders. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2018 Category: Neurology Authors: Kuo-Hua Hung, Jerry Cheng-Yen Lai, Kuang-Nan Hsu, Chihmin Hu, Hung-Chang Chang, Cheng-Neng Chen, He-Shu Ku, Ming-Shiang Yang, Pei-Hao Chen Source Type: research

Antithrombotic Therapy Strategy for Cancer-Associated Ischemic Stroke: A Case Series of 26 Patients
The risk of complications from thromboembolism is increased for patients with malignancy. Cancer-associated stroke is also a serious issue with regard to the management of patients with cancer because stroke incidence often causes disabilities that affect daily life and cancer treatment strategy. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2018 Category: Neurology Authors: Hiroyuki Naito, Tomohisa Nezu, Naohisa Hosomi, Shiro Aoki, Hiroki Ueno, Kazuhide Ochi, Hirofumi Maruyama Tags: Case Studies Source Type: research