Association between Angiotensin-Converting Enzyme Inhibitors and Post-Stroke Aspiration Pneumonia
This study aimed to re-evaluate the preventive effect of ACEIs on post-stroke AP, compared with that of angiotensin II receptor blockers (ARBs). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 18, 2019 Category: Neurology Authors: Ryosuke Kumazawa, Taisuke Jo, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga Source Type: research

Extreme Gradient Boosting Model Has a Better Performance in Predicting the Risk of 90-Day Readmissions in Patients with Ischaemic Stroke
Ischemic stroke readmission within 90 days of hospital discharge is an important quality of care metric. The readmission rates of ischemic stroke patients are usually higher than those of patients with other chronic diseases. Our aim was to identify the ischemic stroke readmission risk factors and establish a 90-day readmission prediction model for first-time ischemic stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 15, 2019 Category: Neurology Authors: Yuan Xu, Xinlei Yang, Hui Huang, Chen Peng, Yanqiu Ge, Honghu Wu, Jiajing Wang, Gang Xiong, Yingping Yi Source Type: research

Risk Stratification for Endovascular Treatment in Acute Anterior Circulation Occlusive Stroke
Objective: To develop and validate a novel scoring system for risk stratification in acute anterior circulation large vessel occlusion stroke patients undergoing endovascular treatment. Methods: Subjects were included from a multicenter registry on acute ischemic stroke undergoing thrombectomy in China. Two thirds of the patients were used as the derivation group and the other one third of the patients as the validation group. Multivariable logistic regression was used to generate the scoring system. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 15, 2019 Category: Neurology Authors: Yunyun Xiong, Huaiming Wang, Meng Zhang, Zhiming Zhou, Wei Wang, Xinfeng Liu, Marc Fisher Source Type: research

Stroke Patients' Status Post-Acute Phase of Illness. How Is It and How Ought It to Be: Ain Shams University Experience
Stroke is a leading cause of disability worldwide with a great impact on quality of life. Ain Shams University Hospital is a tertiary center for neurology and a pioneer in offering comprehensive stroke service in the region. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 15, 2019 Category: Neurology Authors: Tamer Roushdy, Alia H. Mansour, Heba M. Khafaga, Abdulrahman Sayed, Mohamed Fathy, Salwa Eltawil, Tamer Emara Source Type: research

Novel Definition of Stroke “Good Responders” Predicts 90-Day Outcome after Thrombolysis
Identifying predictors of good response in thrombolytic-treated stroke is important to clinical care, resource allocation, and research design. We developed a simple, novel measure of “Good Responders” to assess if 2 short-term variables could predict 90-day outcomes after thrombolysis in stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2019 Category: Neurology Authors: Alyssa E. Bautista, Dawn M. Meyer, Brett C. Meyer Source Type: research

Alcohol Intoxication as a Stroke Mimic and the Incidence of Acute Alcohol Intoxication in Stroke
We describe alcohol intoxication as a stroke mimic and the frequency of acute alcohol intoxication among stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2019 Category: Neurology Authors: Laurien T. Hassing, Merelijne A. Verschoof, Hille Koppen Source Type: research

Stroke Mortality Rates and Trends in Romania, 1994-2017
Background and Aim: Romanian national level stroke mortality data is relatively scarce. The current study investigated stroke mortality rates and trends in Romania. Methods: All individual deaths registered in Romania during 1994-2017 were analyzed using an anonymized database, based on death certificates. Stroke crude mortality rates (CMR) and age-standardized mortality rates (ASMR) were calculated and expressed per 100,000 persons-year. Results: Between 1994 and 2017, 6,281,873 persons died in Romania, stroke being registered as the underlying cause of death in 959,319 cases. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2019 Category: Neurology Authors: Sorin Ioacara, Cristina Tiu, Cristina Panea, Horia Nicolae, Elisabeta Sava, Sorina Martin, Simona Fica Source Type: research

Neurological Deficits in Stroke Patients that May Impede the Capacity to Provide Informed Consent for Endovascular Treatment Trials
We assessed the occurrence of neurological deficits that may impede the capacity to provide consent for trial participation in patients with an acute stroke, who are eligible for endovascular treatment (EVT). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2019 Category: Neurology Authors: Paula M. Janssen, Vicky Chalos, Sophie A. van den Berg, Erwin J.O. Kompanje, Paul J. Nederkoorn, Bart H. van der Worp, Wim H. van Zwam, Diederik W.J. Dippel, MR CLEAN Registry Investigators Source Type: research

Race-Ethnic Disparities in 30-Day Readmission After Stroke Among Medicare Beneficiaries in the Florida Stroke Registry
Objective: To examine racial/ethnic disparities in 30-day all-cause readmission after stroke. Methods: Thirty-day all-cause readmission was compared by race/ethnicity among Medicare fee-for-service beneficiaries discharged for ischemic stroke from hospitals in the Florida Stroke Registry from 2010 to 2013. We fit a Cox proportional hazards model that censored for death and adjusted for age, sex, length of stay, discharge home, and comorbidities to assess racial/ethnic differences in readmission. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2019 Category: Neurology Authors: Hannah Gardener, Erica C. Leifheit, Judith H. Lichtman, Kefeng Wang, Yun Wang, Carolina M. Gutierrez, Maria A. Ciliberti-Vargas, Chuanhui Dong, Mary Robichaux, Jose G. Romano, Ralph L. Sacco, Tatjana Rundek, FL-PR CReSD Investigators and Collaborators Source Type: research

A Cross-Sectional Analysis of Differences in Physical Activity Levels between Stroke Belt and Non-Stroke Belt US Adults
Background: The Stroke Belt is a region of the United States with elevated stroke incidence and prevalence of stroke risk factors. Physical inactivity is an important stroke risk factor, but little is known about whether current physical activity levels differ between Stroke Belt and non-Stroke Belt states. In this nationally representative study, we determined whether unadjusted and adjusted physical activity levels differ between the Stroke Belt region and the rest of the United States. Methods: Using 2017 Behavioral Risk Factor Surveillance System data, we conducted bivariate analyses to obtain unadjusted physical activ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2019 Category: Neurology Authors: Phoebe Tran, Lam Tran, Liem Tran Source Type: research

Is Artery Web Seen in Vertebral Artery?
Carotid artery web has been frequently reported. However, the vertebral artery web has been less reported. It is difficult and seldom to diagnose vertebral artery web with noninvasive examinations. Here, we present a case of asymptomatic vertebral artery web diagnosed by ultrasound and confirmed by digital subtraction angiography. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2019 Category: Neurology Authors: Lizhang Chen, Lanxin Du, Xiaorong Wen, Yi Jiang, Fayun Hu, Hongbo Zheng Tags: Case Report Source Type: research

Hemicrania Continua Subsequent to Vertebral Artery Dissection: A Case Report
We herein report the case of a 45-year-old woman who developed a continuous hemicranial headache subsequent to vertebral artery dissection (VAD). After remission of VAD, the patient repeatedly experienced right forehead and temporal region throbbing headache, accompanied by nausea, ocular hyperemia and lacrimation of the right eye, nasal congestion, and rhinorrhea. Magnetic resonance angiography did not reveal the recurrence of dissection. Daily use of indomethacin (190.8 mg/day) showed an excellent effect on the headache, suggesting that the patient had developed hemicrania continua subsequent to VAD. (Source: Journal of ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2019 Category: Neurology Authors: Hiromitsu Tabata, Hiroshi Kitaguchi Source Type: research

Even Faster Door-to-Alteplase Times and Associated Outcomes in Acute Ischemic Stroke
We report a single-center, retrospective assessment of the safety and efficacy of alteplase treatment within 45 minutes. Methods: Five hundred and eighty-six patients were treated with alteplase in our emergency departments (EDs) between January 2014 and October 2016; 368 patients were included for analysis. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2019 Category: Neurology Authors: Sarah Jung, Jamie M. Rosini, Jason T. Nomura, Richard J. Caplan, Jonathan Raser-Schramm Source Type: research

Embolic Stroke of Undetermined Source in Saudi Arabia: Prevalence, Patient Characteristics, and Outcomes
Background: Embolic stroke of undetermined source (ESUS) is a newly introduced clinical construct to better characterize cryptogenic stroke. It is associated with considerable morbidity and mortality and a high recurrence rate. It has not previously been investigated in Saudi stroke patients. We aimed to conduct a descriptive analysis of ESUS in Saudi Arabia, including its frequency among patients with acute stroke, characteristics, and outcomes. Methods: We reviewed all ischemic stroke patients admitted to the stroke unit at King Abdulaziz Medical City-Riyadh, Saudi Arabia, from February 2016 to July 2018. (Source: Journa...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2019 Category: Neurology Authors: Ali M. Al Khathaami, Bayan Al Bdah, Abdulmjeed Alnosair, Rayan Alrebdi, Shorug Alwayili, Sulaiman Alhamzah, Abdulkarim Al Turki, Nasser Alotaibi Source Type: research

Response to “Potential Clinical and Radiographic Horizontal Gaze Deviation an Early Sign of Stroke”
We would like to thank Dr. Kattah for commenting on our article “Degree of Conjugate Gaze Deviation on CT Predicts Proximal Vessel Occlusion and May Expedite Endovascular Therapy”. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2019 Category: Neurology Authors: Nan N. Jiang, Crystal Fong, Demetrios J. Sahlas, Sandra Monteiro, Ramiro Larrazabal Tags: Letter to the Editor Source Type: research

Coronary Artery Disease in Patients with Ischemic Stroke and TIA
Ischemic stroke (IS) and coronary artery disease (CAD) share common risk factors and one may be the harbinger of the other. We aimed to study prevalence of symptomatic and asymptomatic CAD in a cohort of consecutive patients with IS and assess its relationship with intracranial and extracranial large artery cerebrovascular disease (LAD). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2019 Category: Neurology Authors: Rohit Bhatia, Gautam Sharma, Chetan Patel, Ajay Garg, Ambuj Roy, Prerna Bali, Nishita Singh, Pranjal Sisodia, Vishnubhatla Sreenivas, M.V. Padma Srivastava, Kameshwar Prasad Source Type: research

Prehospital and Emergency Department-Focused Mission Protocol Improves Thrombolysis Metrics for Suspected Acute Stroke Patients
Background: The Mission Protocol was implemented in 2017 to expedite stroke evaluation and reduce door-to-needle (DTN) times at Zuckerberg San Francisco General Hospital. The key system changes were team-based evaluation of suspected stroke patients at ambulance entrance by an Emergency Department (ED) physician, ED nurse, and neurologist and immediate emergency medical service (EMS) provider transport of patients to CT. Methods: Patients were eligible for a Mission Protocol prehospital stroke activation if an EMS provider found a positive Cincinnati Prehospital Stroke Scale and a last known normal time within 6 hours. (So...
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2019 Category: Neurology Authors: Debbie Y. Madhok, Kevin J. Keenan, Sara B. Cole, Christine Martin, J. Claude Hemphill Source Type: research

Propofol Reduces Inflammatory Brain Injury after Subarachnoid Hemorrhage: Involvement of PI3K/Akt Pathway
Background: Our previous study showed that propofol, one of the widely used anesthetic agents, can attenuate subarachnoid hemorrhage (SAH)-induced early brain injury (EBI) via inhibiting inflammatory and oxidative reaction. However, it is perplexing whether propofol attenuates inflammatory and oxidative reaction through modulating PI3K/Akt pathway. The present study investigated whether PI3K/Akt pathway is involved in propofol's anti-inflammation, antioxidation, and neuroprotection against SAH-induced EBI. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 4, 2019 Category: Neurology Authors: Hua-bin Zhang, Xian-kun Tu, Quan Chen, Song-sheng Shi Source Type: research

Effectiveness of an Interdisciplinary, Nurse Driven In-Hospital Code Stroke Protocol on In-Patient Ischemic Stroke Recognition and Management
Background: In-hospital strokes account for up to nearly 1 in 5 strokes. Clinical outcomes, such as length of stay, disability, and mortality are worse for in-hospital strokes than for those that occur in the community. For a variety of reasons, stroke can be more difficult to recognize and treat in hospitalized patients. Earlier recognition of stroke results in better clinical outcomes, presumably due to faster diagnosis and subsequently, prompt treatment. Methods: This investigation was a retrospective, interrupted time series, observational study of all in-hospital stroke patients between 2008 and 2017. (Source: Journal...
Source: Journal of Stroke and Cerebrovascular Diseases - October 2, 2019 Category: Neurology Authors: Sarah Jane Yang, Th érèse Franco, Nicolai Wallace, Barbara Williams, Craig Blackmore Source Type: research

Repetitive Transcranial Magnetic Stimulation for the Treatment of Lower Limb Dysfunction in Patients Poststroke: A Systematic Review with Meta-Analysis
To investigate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) in recovery of lower limb dysfunction in patients poststroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 2, 2019 Category: Neurology Authors: Mahboubeh Ghayour-Najafabadi, Amir-Hossein Memari, Lida Hosseini, Ardalan Shariat, Joshua A. Cleland Tags: Review Article Source Type: research

Clinical Study of Thirteen Patients with Spinal Cord Infarction
A concept of sensory tracts in the spinal cord has been established in relation to a dorsolateral pathway which is located in the posterior part of the lateral column and conveys the deep sense. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 1, 2019 Category: Neurology Authors: Katsuhiko Ogawa, Takayoshi Akimoto, Makoto Hara, Akihiko Morita, Midori Fujishiro, Yutaka Suzuki, Masayoshi Soma, Satoshi Kamei, Hideto Nakajima Source Type: research

Hyponatremia in Acute Stroke: To Treat or Not to Treat?
Hyponatremia is the most common electrolyte disorder both in hospitalized patients and individuals from the community with a reported incidence mounting up to 30% and 8%, respectively.1,2 Its association with increased risk of mortality has been well-established.3-5 Several meta-analyses have demonstrated that hyponatremia increases mortality in patients with common clinical conditions, such as acute myocardial infarction, heart failure, cirrhosis, and chronic kidney disease,3-5 while “correction” of serum sodium levels improves survival. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 1, 2019 Category: Neurology Authors: Fotios Barkas, George Liamis, Haralampos Milionis Tags: Letter to the Editor Source Type: research

The Effect of Occupation-Based Bilateral Upper Extremity Training in a Medical Setting for Stroke Patients: A Single-Blinded, Pilot Randomized Controlled Trial
Background: Occupation used in occupation-based intervention requires the use of 2 naturally coordinated hands. Objective: To investigate by implementing occupation-based bilateral upper extremity training in medical setting to stroke patients and determine its effect in patients ’ bilateral upper extremity function recovery. Methods: A total of 20 patients were randomly assigned to the experimental group (occupation-based bilateral upper extremity training) or control group (task-based bilateral upper extremity training). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2019 Category: Neurology Authors: Sun Ho Kim, Ji Hyuk Park Source Type: research

Transient Ischemic Attack: Which Determines Diffusion-Weighted Image Positivity?
Diffusion-weighted image (DWI) of magnetic resonance imaging (MRI) can reveal high signal lesion in up to 50% of transient ischemic attack (TIA) patients. However, it is not well-known which factors determine developing DWI positivity. In order to answer this question, we analyzed factors relevant to DWI positivity in TIA patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2019 Category: Neurology Authors: Yosuke Aiba, Ryuji Sakakibara, Fuyuki Tateno, Tsuyoshi Ogata, Takeki Nagao, Hitoshi Terada, Tsutomu Inaoka, Tomoya Nakatsuka Source Type: research

Severe Periodontitis Is Associated with Early-Onset Poststroke Depression Status
In this study, we aimed to investigate whether there is an association between severe periodontitis and PSD status in acute ischemic stroke patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2019 Category: Neurology Authors: Weifeng Lin, Li Xiong, Zhi Yang, Xuhui Deng, Jinhua Zhu, Chunchun Chen, Shuxuan Huang, Ying Ma, Feiqi Zhu Source Type: research

Acute Cerebral Infarction in a Patient with Persistent Trigeminal Artery and Homolateral Hypoplasia of Internal Carotid Artery Distal Anastomosis: A Case Report and a Mini Review of the Literature
Persistent primitive trigeminal artery (PPTA) is a rare remnant between the internal carotid artery (ICA) and the basilar artery into adulthood. PPTA generally lacks specific clinical manifestations and occasionally accompanies with other cerebrovascular diseases. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 28, 2019 Category: Neurology Authors: Da-Ping Lyu, Yu Wang, Kai Wang, Ming Yao, Yun-Fan Wu, Zhi-Hua Zhou Source Type: research

Timing of Direct Enteral Tube Placement and Outcomes after Acute Stroke
Background: Direct enteral feeding tube (DET) placement for dysphagia after stroke is associated with poor outcomes. However, the relationship between timing of DET placement and poststroke mortality and disability is unknown. We sought to determine the risk of mortality and severe disability in patients who receive DET at different times after stroke. Methods: We used the Ontario Stroke Registry and linked administrative databases to identify patients with acute ischemic stroke or intracerebral hemorrhage between 2003 and 2013 who received DET (gastrostomy or jejunostomy) during their hospital admission. (Source: Journal ...
Source: Journal of Stroke and Cerebrovascular Diseases - September 28, 2019 Category: Neurology Authors: Raed A. Joundi, Gustavo Saposnik, Rosemary Martino, Jiming Fang, Moira K. Kapral Source Type: research

Transcutaneous Auricular Vagus Nerve Stimulation with Upper Limb Repetitive Task Practice May Improve Sensory Recovery in Chronic Stroke
We report the impact of taVNS paired with a motor intervention, repetitive task practice, on sensory recovery in a cohort of patients with chronic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2019 Category: Neurology Authors: Sheharyar Sajjad Baig, Konstantinos Falidas, Peter J. Laud, Nicola Snowdon, Muhammad Umar Farooq, Ali Ali, Arshad Majid, Jessica N. Redgrave Source Type: research

An Observational Cohort Study Investigating Risk of Malnutrition Using the Malnutrition Universal Screening Tool in Patients with Stroke
Background: Malnutrition in patients hospitalized with a stroke have been assessed using different nutritional screening methods but there is a paucity of data linking risk of malnutrition to clinical outcomes using a validated tool. Aims: To identify the prevalence of malnutrition risk in patients after a stroke and assess the predictive value of the Malnutrition Universal Screening Tool (MUST) on clinical outcomes. Patients and Methods: Using data from electronic records and the Sentinel Stroke National Audit Programme (January 2013 and March 2016), patients aged more than 18 years with confirmed stroke admitted to a ter...
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2019 Category: Neurology Authors: Jana Sremanakova, Sorrel Burden, Yassin Kama, Mathew Gittins, Simon Lal, Craig J. Smith, Shaheen Hamdy Source Type: research

High Intensity Exercise for Walking Competency in Individuals with Stroke: A Systematic Review and Meta-Analysis
Objective: To assess the effects of high intensity exercise on walking competency in individuals with stroke. Data sources: A systematic electronic searching of the PubMed, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL (EBSCOhost), and SPORTSDiscus (EBSCOhost) was initially performed up to June 25, 2019. Study selection: Randomized controlled trials or clinical controlled trials comparing any walking or gait parameters of the high intensity exercise to lower intensity exercise or usual physical activities were included. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2019 Category: Neurology Authors: Lu Luo, Shiqiang Zhu, Luoyi Shi, Peng Wang, Mengying Li, Song Yuan Source Type: research

Carotid Webs in Cryptogenic Ischemic Strokes: A Matched Case-Control Study
Background: Young individuals with symptomatic carotid webs may be predisposed to ischemic strokes. However, evidence remains scarce. This investigation reports the frequency of carotid webs among patients with cryptogenic strokes compared to a control group. Methods: Consecutive cryptogenic ischemic strokes and trauma patients were identified. Additional inclusion criteria required age 18-60 years and availability of head/neck computed tomography (CT) angiography. CT angiogram (CTA) neck images were evaluated independently by 2 fellowshiptrained specialists. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2019 Category: Neurology Authors: Song J. Kim, Jason W. Allen, Mehdi Bouslama, Fadi Nahab, Michael R. Frankel, Raul G. Nogueira, Diogo C. Haussen Source Type: research

Cerebral Air Embolism after Esophagogastroduodenoscopy: Insight on Pathophysiology, Epidemiology, Prevention and Treatment
Air embolism is an extremely rare complication that can follow gastrointestinal endoscopy. The most accepted treatment of cerebral air embolism (CAE) is hyperbaric oxygen (HBO). Limited evidence suggests that lidocaine may have a neuroprotective effect. The exact mechanism does not appear to be well elucidated. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2019 Category: Neurology Authors: Malik Ghannam, Azizullah Beran, Dana Ghazaleh, Tanner Ferderer, Brent Berry, Mona Al Banna, Leighton Mohl, Christopher Streib, Tapan Thacker, Ivan Matos Source Type: research

Effect of Known Atrial Fibrillation and Anticoagulation Status on the Prehospital Identification of Large Vessel Occlusion
Introduction: The Cincinnati Prehospital Stroke Severity scale (C-STAT), Los Angeles Motor Scale (LAMS), Rapid Arterial Occlusion Evaluation (RACE) score, and Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scales were designed to aid emergency responder identification of patients with stroke related to large vessel occlusion (LVO). We hypothesized that the addition of a known history of atrial fibrillation (AF) without anticoagulation to currently used scales would improve LVO detection. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2019 Category: Neurology Authors: Parneet Grewal, Sourabh Lahoti, Sushanth Aroor, Kaitlin Snyder, Luther C. Pettigrew, Larry B. Goldstein Source Type: research

Masthead
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2019 Category: Neurology Source Type: research

Editorial Board
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2019 Category: Neurology Source Type: research

Table of Contents
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2019 Category: Neurology Source Type: research

Introducing article numbering to Journal of Stroke and Cerebrovascular Diseases
(Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2019 Category: Neurology Source Type: research

Comparison of Automated CT Perfusion Softwares in Evaluation of Acute Ischemic Stroke
Background and Purpose: Automated imaging software is integral to decision-making in acute ischemic stroke (AIS) during extended time windows. RAPID software is the most widely used and has been validated in landmark endovascular trials. Olea software is another commercially available and FDA-approved software, but has not been studied in AIS trials. We aimed to compare the diagnostic utility and accuracy of RAPID and Olea in everyday clinical practice outside of a clinical trial. Methods: We analyzed prospectively-collected data from a consecutive cohort of 141 patients with suspected AIS who underwent computed tomography...
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2019 Category: Neurology Authors: Yunyun Xiong, Chiwen C. Huang, Marc Fisher, David B. Hackney, Rafeeque A. Bhadelia, Magdy H. Selim Source Type: research

Significant Stroke Knowledge Deficiencies in Community Physician Improved with Stroke 120
Background and Purpose: In the existing model of community health service in China, community general practitioners play important roles in health promotion as well as prehospital stroke recognition and management. We recently engineered Stroke 120 based on FAST for China. This investigation aimed to investigate its acceptance in community physicians and promote their stroke related knowledge. Methods: We conducted an stroke education session to community physicians or family doctors (total of 435 participants), teaching both FAST and Stroke 120. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 24, 2019 Category: Neurology Authors: Xiaochuan Liu, Yingfeng Weng, Renyu Liu, Jing Zhao Source Type: research

Preprocedure Intravenous Recombinant Tissue Plasminogen Activator and Risk of Distal Embolization with Thrombectomy in Acute Ischemic Stroke
Background: Intravenous recombinant tissue plasminogen activator (IV rt-PA) prior to thrombectomy may reduce the risk of intraprocedural distal embolization in acute ischemic stroke patients. Methods: We analyzed the diffusion-weighted imaging acquired with 1.5- or 3-T magnetic resonance imaging (MRI) scans obtained within 24 hours of thrombectomy in consecutive acute ischemic stroke patients. An independent physician identified distal embolization, defined as discrete foci of restricted diffusion independent of the primary area of infarction on MRI scan. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 24, 2019 Category: Neurology Authors: Adnan I. Qureshi, Ahmer Asif, Emrah Aytac, Jahanzeb Liaqat, Erdem Gurkas, Iryna Lobanova, Omar Saeed, Humera Ahsan, Farhan Siddiq, Camilo R. Gomez, Brandi R. French Source Type: research

Cerebral Venous Sinus Thrombosis as a Rare Complication of Systemic Lupus Erythematosus: Subgroup Analysis of the VENOST Study
Systemic lupus erythematosus (SLE) is an unusual risk factor for cerebral venous sinus thrombosis (CVST). As few CVST patients with SLE have been reported, little is known regarding its frequency as an underlying etiology, clinical characteristics, or long-term outcome. We evaluated a large cohort of CVST patients with SLE in a multicenter study of cerebral venous thrombosis, the VENOST study, and their clinical characteristics. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 24, 2019 Category: Neurology Authors: Task ın Duman, Seden Demirci, Derya Uluduz, Hasan Hüseyin Kozak, Serkan Demir, Cemile Handan Mısırlı, Hayriye Küçükoğlu, Nilgün Çınar, Füsun Mayda Domaç, Şerefnur Öztürk, VENOST Study Group, Mehmet Ali Sungur, Vildan Yayla, Ali Yavuz Kara Source Type: research

Corrigendum to ‘Reduced Doses of Direct Oral Anticoagulants in Ischemic Stroke Patients with Nonvalvular Atrial Fibrillation’ [Journal of Stroke and Cerebrovascular Diseases, Volume 28, (2019) 354-359]
The authors regret: (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 24, 2019 Category: Neurology Authors: Ichiro Deguchi, Masaki Takao Source Type: research

Risk of Hyperglycemia and Hypoglycemia in Patients with Acute Ischemic Stroke Based on Continuous Glucose Monitoring
In patients with acute ischemic stroke, current guidelines recommend maintaining blood glucose levels in a range of 140-180 mg/dL and closely monitoring to prevent hypoglycemia ( (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 21, 2019 Category: Neurology Authors: Saki Nukui, Hisanao Akiyama, Kaima Soga, Naoki Takao, Yoko Tsuchihashi, Naoki Iijima, Yasuhiro Hasegawa Source Type: research

Predicting the Risk of Stroke in Chinese Internal Carotid Artery Stenosis Patients Underwent Carotid Artery Stenting: Validation and Improvement of Siena Carotid Artery Stenting Risk Score
Background: Siena carotid artery stenting (CAS) risk score is developed based on Chinese internal carotid artery (ICA) stenosis patients recruited in Italy, whether it is equally applicable in Chinese remains unknown. We aimed to investigate Siena CAS risk score value for predicting stroke risk in ICA stenosis patients underwent CAS and explore additional factors for improving accuracy of scoring system. Methods: Totally 401 patients with ICA stenosis who underwent CAS were enrolled. The clinical data (including patient characteristics, lesion features, and procedure-related features) were collected and the Siena CAS score...
Source: Journal of Stroke and Cerebrovascular Diseases - September 21, 2019 Category: Neurology Authors: Huchuan Zhou, Lin Shen, Fei Wei, Jie Shuai Source Type: research

Water-Based Exercise on Functioning and Quality of Life in Poststroke Persons: A Systematic Review and Meta-Analysis
Objective: To investigate the effects of water-based exercise on functioning and quality of life in poststroke persons. Data Sources: We searched the following electronic database: MEDLINE, PeDro, Scielo, and the Cochrane Central Register of Controlled Trials up to September 2018 Study Selection: Only randomized controlled trials were included. Two review authors screened the titles and abstracts and selected the trials independently. Data Extraction: Two review authors independently extracted data of the included trials, using standard data-extraction model. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 18, 2019 Category: Neurology Authors: Micheli B. Saquetto, C ássio M. da Silva, Bruno P. Martinez, Cristiano da Conceição Sena, Sarah S. Pontes, Mayra T.C. da Paixão, Mansueto Gomes Neto Tags: Review Article Source Type: research

Effects of the Interaction among Motor Functions on Self-care in Individuals with Stroke
No study to date has focused on what combinations of motor functions are strongly associated with self-care independence in individuals with stroke. The purpose of this study is to clarify the impact of motor function interactions on self-care independence in individuals with stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 18, 2019 Category: Neurology Authors: Takaaki Fujita, Kazuaki Iokawa, Toshimasa Sone, Kazuhiro Yamane, Yuichi Yamamoto, Yoko Ohira, Koji Otsuki Source Type: research

Association of Ultrasonography and MRI Findings with Stroke Recurrence: Differences Between Patients with Past Histories of Atherothrombotic Versus Lacunar Infarctions
This study investigated the association of MRI and ultrasonography findings with stroke recurrence in patients with past histories of atherothrombotic infarctions (ATIs) or lacunar infarctions (LIs). Methods: We prospectively analyzed the incidence of stroke recurrence. Deep and lobar cerebral microbleeds (MBs), asymptomatic lacunae, asymptomatic intracerebral hemorrhages (ICHs), severe white matter lesions (WML), and intima-media thickness (IMT) were investigated on enrollment. Stroke recurrence rates were compared by using the log-rank test. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 18, 2019 Category: Neurology Authors: Toshio Imaizumi, Shigeru Inamura, Aya Kanno, Tatsufumi Nomura, Sang Nyon Kim Source Type: research

Causes, Predictors, and Trends of Unplanned Readmissions after Elective Endovascular Embolization of Cerebral Aneurysms
Background: 30- and 90-day readmissions (dRA) are being increasingly scrutinized as quality metrics for hospital and provider performances. Little information regarding risk factors for readmission after elective endovascular treatment (EVT) of an unruptured cerebral aneurysm (UCA) is available. Methods: The Nationwide Readmissions Database was used to identify patients who underwent elective endovascular embolization of an unruptured aneurysm between 2010 and 2014. The primary outcomes of interest were unplanned readmissions occurring within 30 or 90 days of discharge. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 18, 2019 Category: Neurology Authors: Haydn Hoffman, Matthew Protas, Lawrence S. Chin Source Type: research

Potential Clinical and Radiographic Horizontal Gaze Deviation an Early Sign of Stroke
The recent article from Jiang et al “Degree of Conjugate Gaze Deviation on CT Predicts Proximal Vessel Occlusion and May Expedite Endovascular Therapy,” Journal of Stroke and Cerebrovascular Disease 2019; 28:1093-10981 provides valuable information that may lead to early stroke intervention. They found that radiographic horizontal gaze deviation (h-CGD) detected by CTA is frequently associated with a proximal arterial occlusion (either ICA or proximal segments of the MCA); the h-CGD was always ipsilesional. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2019 Category: Neurology Authors: Jorge C. Kattah Tags: Letter to the Editor Source Type: research

Alcohol-Related Hospital Encounters Trigger Thrombotic and Hemorrhagic Vascular Events
We investigated the associations between alcohol-related emergency department visits and hospitalizations and vascular events including acute ischemic stroke, intracerebral hemorrhage (ICH), and subarachnoid hemorrhage. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2019 Category: Neurology Authors: Caroline Gentile, Laura Stein, Mandip S. Dhamoon Source Type: research