Fly and treat: Endovascular treatment of ruptured aneurysms at an insular tertiary center
This study examines a novel protocol implemented in 2016 at Regi ão Autónoma da Madeira, a Portuguese island. It involves the mobilization of experienced neurointerventionalists from high-volume hospitals to provide aSAH treatment. (Methods) We conducted a retrospective analysis on 30 aSAH patients who underwent endovascular treatment at the island center betwe en November 2016 and April 2022. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2023 Category: Neurology Authors: Sofia Almeida Xavier, Alexandra Rodrigues, Torcato Meira, Hugo Mota D ória, Carolina Figueira, José Amorim, Ricardo Pestana, Júlio Nobrega, José Franco, Ângelo Carneiro Source Type: research

Progressive lacunar strokes behave differently from stable ones even at one year —An observational study
Lacunar strokes [LS] caused by occlusion of a single penetrating branch of a larger cerebral artery accounts for 15 –26 % of all ischemic strokes.1 The perforator occlusion causes a small subcortical infarct typically of size less than 20 mm and presents with a well-defined clinical syndrome.2 These strokes are usually of mild-moderate severity3,4 with overall favorable short term outcome. However, in a subgr oup, progression or early neurological deterioration is reported, known as progressive lacunar syndromes [PLS]. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2023 Category: Neurology Authors: K Y Manisha, Raviprasad Varma, P N Sylaja, Sapna Erat Sreedharan Source Type: research

Acute phase supra-aortic intraluminal thrombus signal changes on magnetic resonance angiography: A case series
Intraluminal thrombus (ILT) is a relatively rare cause of stroke. MRI/MRA is increasingly used for stroke patients eligible for acute treatment. Radiological ILT characteristics have never been studied systematically on MRA. We aimed to analyse signal changes and other radiological characteristics of ILT in the acute phase on MRA in a case series of ILT patients. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2023 Category: Neurology Authors: Dimitri Renard, Wilfried Ekue, Anne Wacongne, Teodora Parvu, Eric Thouvenot Source Type: research

Deciphering the contextual barriers to mainstreaming the implementation of stroke thrombolysis in a Ghanaian hospital: Findings from the activate mixed-methods study
Stroke is a significant global health concern, with the majority of stroke-related deaths and disability occurring in Low-middle-income-countries (LMICs), where acute stroke care is subpar.1 The provision of timely and effective acute stroke management is crucial for improving outcomes. Ideally, acute stroke care should be provided by a comprehensive stroke center capable of performing thrombolysis and mechanical thrombectomy.2 However, the reality in LMICs, including Ghana, is that very few facilities meet these recommended standards. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 20, 2023 Category: Neurology Authors: Priscilla Abrafi Opare-Addo, Chris Oppong, Rexford Adu Gyamfi, Minas Aikins, Lawrence Nsohlebna Nsoh, Serwaa Asare-Bediako, Emmanuel Attafuah, Kofi Sarfo, Augustine Kwakye Sampah, Jonathan Boakye Yiadom, Fred Stephen Sarfo Source Type: research

Prevalence of intracranial artery stenosis in a general population using 3D-time of flight magnetic resonance angiography
Intracranial artery stenosis (ICAS) is a common cause of stroke in Asians, Hispanics and African Americans1 –4, with high risk of stroke recurrence.4,5 In Caucasians extracranial carotid artery atherosclerosis has been considered the predominant cause of stroke, whereas ICAS has been of minor importance,5,6 but the real impact of ICAS in western populations may however have been underestimated.7–9 (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 20, 2023 Category: Neurology Authors: Liv-Hege Johnsen, Marit Herder, Torgil Vangberg, J ørgen Gjernes Isaksen, Ellisiv B. Mathiesen Source Type: research

In reply to the Letter to the Editor regarding: Healthcare expenditure trends among adult stroke patients in the United States, 2011-2020
We would like to thank Sterpetti and colleagues for their interest in our study.1 The findings of our study showed that stroke patients incur notably higher healthcare costs in comparison to those who did not experience stroke.1 This disparity is attributed to increased spending on inpatient services, prescription medications, and visits to healthcare providers. These results are concerning because stroke prevalence is projected increase in the future due to both aging population and improved survival rates. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 20, 2023 Category: Neurology Authors: Venkataraghavan Ramamoorthy, Sandeep Appunni, Mukesh Roy, Anshul Saxena, Muni Rubens Tags: Letter to the Editor Source Type: research

A smartphone pupillometry tool for detection of acute large vessel occlusion
Pupillary light reflex (PLR) parameters can be used as quantitative biomarkers of neurological function. Since digital infrared pupillometry is expensive, we sought to examine alterations in PLR parameters using a smartphone quantitative pupillometry platform in subjects with acute ischemic stroke (AIS). (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2023 Category: Neurology Authors: Anthony J. Maxin, Bernice G. Gulek, John Chae, Graham Winston, Philine Weisbeek, Lynn B. McGrath, Michael R. Levitt Source Type: research

Impaired T1 mapping and Tmax during the first 7 days after ischemic stroke. A retrospective observational study
In acute ischemic stroke, energy expenditure results in swelling of brain cells (cytotoxic edema), which is followed by transvascular cerebral edema (ionic edema and vasogenic edema) and an increase in the total water content of brain tissue1. The degree of brain edema is strongly predictive of patient functional outcomes2. In addition, due to the presence of edema, the volume of the ischemic core is often overestimated3,4. Therefore, evaluating the degree of brain edema is helpful to analyze the evolution of infarction more accurately in patients with ischemic stroke. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2023 Category: Neurology Authors: Lianfang Shen, Xiudi Lu, Huiying Wang, Gemuer Wu, Yu Guo, Shaowei Zheng, Lei Ren, Huanlei Zhang, Lixiang Huang, Bo Ren, Jinxia Zhu, Shuang Xia Source Type: research

Association between switching prescribed drugs for lower urinary tract symptoms and independence of urination in post-stroke patients: A retrospective cohort study
Stroke patients frequently exhibit loss of independence of urination, and their lower urinary tract symptoms change with the phase of stroke. However, it is unclear whether switching prescribed drugs for lower urinary tract symptoms during hospitalization from acute care wards to convalescence rehabilitation wards affects patients' independence of urination at discharge. It is also unclear whether the impact of switching varies by stroke type. This retrospective cohort study aimed to examine these issues. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2023 Category: Neurology Authors: Koyomi Sumiya, Miho Shogenji, Yasunori Ikenaga, Yoru Ogawa, Kohei Hirako, Arimi Fujita, Tsutomu Shimada, Masako Hashimoto, Akio Masuda, Takehito Nagamoto, Ikumi Tamai, Hisayuki Ogura, Tadashi Toyama, Takashi Wada, Yoshimichi Sai Source Type: research

Effect of rehabilitation motivation on improving activities of daily living in subacute stroke patients
To determine the effect of rehabilitation motivation on activities of daily living improvement in subacute stroke patients starting intensive rehabilitation. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 13, 2023 Category: Neurology Authors: Shinnosuke Ishida, Hiroaki Harashima, Satoshi Miyano, Kennosuke Kawama Source Type: research

Hyperbaric oxygen improves cerebral ischemia-reperfusion injury in rats via inhibition of ferroptosis
In this study, we aimed to establish a rat model of cerebral ischemia-reperfusion, explore the possible role of ferroptosis in the pathogenesis of CIRI, and observe the effect of HBO on ferroptosis-mediated CIRI. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 13, 2023 Category: Neurology Authors: Wan Chen, Xing Zhou, Mingyu Meng, Xiaorong Pan, Luying Huang, Chunxia Chen Source Type: research

Can mechanical thrombectomy be effective in deep cerebral venous thrombosis worsening on anticoagulant? Insight from two cases
Cerebral venous thrombosis (CVT) is a rare condition whose clinical presentation can range from simple headaches to severe impairment of alertness. Some clinical forms, such as involvement of the deep venous system, are associated with a poorer clinical prognosis despite well-managed anticoagulation. The role and timing of rescue mechanical thrombectomy for these patients is not well established. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 13, 2023 Category: Neurology Authors: Marine Glineur, Anne Dusart, Nicolas Cavez, Illario Tancredi, Flavio Bellante Tags: Case Report Source Type: research

Continuity and Change in Baseline Stroke Knowledge across the world: Second Wave of FAST Heroes campaign implementation
In this work we present the results of the implementation of a globally representative educational school-based stroke awareness programme, FAST (Face, Arm, Speech, Time) Heroes during the second year of education (wave 2). We aimed to observe changes in baseline stroke knowledge between wave 1 and wave 2, distinguish the more fine-grained effect of the campaign on society, and evaluate changes before and after the implementation of wave 2. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 13, 2023 Category: Neurology Authors: Jan van der Merwe, Kalliopi Tsakpounidou, Maria Baskini, Chris Webb, Christos Keramydas, Sheila Cristina Ouriques Martins, Marianne Elisabeth Klinke, Hariklia Proios Source Type: research

Emergent use of ticagrelor during endovascular reperfusion in large arterial occlusions
We report our experience of Ticagrelor use in revascularization of acute large arterial steno-occlusive disease, describing procedural post-procedure thrombotic events, major hemorrhages, and other clinical outcomes. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - October 12, 2023 Category: Neurology Authors: Song J. Kim, Stephen W. English, Katleen W. Chester, Olivia J. Morgan, Michael R. Frankel, Raul G. Nogueira, Alhamza R. Al-Bayati, Diogo C. Haussen Source Type: research

Relationship between prior statin therapy and radiological features and clinical outcomes of intracerebral hemorrhage
Besides lowering cholesterol level via inhibition of hydroxymethyl-glutaryl-CoA (HMG-CoA) reductase, statins have other putative pleiotropic effects.1 Several preclinical studies suggest that statins exert neuroprotective effects after intracerebral hemorrhage (ICH) by reducing brain edema, accelerating hematoma clearance, and improving neurologic function.2-6 These benefits have been attributed to statin's effects on increased neurogenesis, decreased endothelial inflammatory response and inflammatory cell infiltration in the hematomal and perihematomal brain tissues, increased hematoma reabsorption, protection and mainten...
Source: Journal of Stroke and Cerebrovascular Diseases - October 12, 2023 Category: Neurology Authors: Kun He Lee, Filipa Carvalho, Vasileios-Arsenios Lioutas, Elizabeth Heistand, Alvin S. Das, Sarah Marchina, Ashkan Shoamanesh, Aristeidis H. Katsanos, Amjad Shehadah, Diego Incontri, Magdy Selim Source Type: research