Isatin as a 2-aminobenzaldehyde surrogate: transition metal-free efficient synthesis of 2-(2 ′-aminophenyl)benzothiazole derivatives
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00888E, PaperManpreet Singh, Vaishali, Avijit Kumar Paul, Virender Singh A transition metal-free gram-scale strategy has been formulated to access 2-(2 ′-aminophenyl)benzothiazole based luminescent materialsvia the formation of one C –N and two C–S bonds in a single operation. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 3, 2020 Category: Molecular Biology Authors: Manpreet Singh Source Type: research

Novel usage of 2-BTSO2CF2H for metal-free electrophilic difluoroalkanethiolation of indoles
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00872A, CommunicationJun Wei, Kun Bao, Yuan Wang, Rong Sheng, Jinbo Hu 2-BTSO2CF2H was used as an efficient electrophilic –SCF2H synthon for the first time for the metal-free electrophilic difluoromethylthiolation of indoles. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 3, 2020 Category: Molecular Biology Authors: Jun Wei Source Type: research

Organocatalytic enone-azide [3 + 2]-cycloaddition: synthesis of functionally rich C/N-double vinyl 1,2,3-triazoles
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00848F, PaperG. Surendra Reddy, A. Suresh Kumar, Dhevalapally B. Ramachary C/N-Double vinyl-1,2,3-triazoles were furnished in very good yields with excellent selectivity by using an organocatalytic [3 + 2]-cycloaddition of enones with azides under ambient conditions. Many of the vinyl-1,2,3-triazoles have shown medicinal properties. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 3, 2020 Category: Molecular Biology Authors: G. Surendra Reddy Source Type: research

Chemical methods for modification of proteins
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00857E, Review ArticleNeelesh C. Reddy, Mohan Kumar, Rajib Molla, Vishal Rai The library of chemical reactions for C-C and C-heteroatom bond formation is exceptional. The understanding of reactivity and diverse aspects of selectivity facilitates the functional group transformation of high complexity.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 2, 2020 Category: Molecular Biology Authors: Neelesh C. Reddy Source Type: research

Electrochemical regioselective alkylations of [60]fulleroindoline with bulky alkyl bromides
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00876A, PaperYong Yang, Chuang Niu, Muqing Chen, Shangfeng Yang, Guan-Wu Wang The electrochemical alkylations of a [60]fulleroindoline with different bulky alkyl bromides exhibit different reaction behaviors. The hydroalkylation and dialkylation of the electrochemically generated dianionic [60]fulleroindoline with bulky 2,4,6-tris(bromomethyl)mesitylene gives rise... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 2, 2020 Category: Molecular Biology Authors: Yong Yang Source Type: research

Synthesis and Applications of Porphyrin-contained Pillararenes
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00763C, Review ArticleHuacheng Zhang, Jie Han Porphyrin-pillararenes hybrid compounds/systems have attracted much more attention due to their synergistic effect generated by combining two significant macrocycles in supramolecular chemistry together. On one side, porphyrin units could serve... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 2, 2020 Category: Molecular Biology Authors: Huacheng Zhang Source Type: research

Recent Advances in Oximes-participated Synthesis of Isoxazolines
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00963F, Review ArticleJianhua Liao, Lu Ouyang, Qi Jin, Jian Zhang, Renshi Luo Isoxazoline compounds are used as important intermediates for the synthesis of organic molecules which are widely used in the chemical and life science industries. Oximes-participated cyclization has emerged as an... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 2, 2020 Category: Molecular Biology Authors: Jianhua Liao Source Type: research

Synthesis and practical applications of 2-(2-nitroalkyl) pyrroles.
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00956C, Review ArticleAlessandro Palmieri, Marino Petrini Functionalization of pyrroles introducing a 2-nitroalkyl moiety allows the formation of nitro-containing compounds to be used as pivotal intermediates for the synthesis of bioactive compounds. Reaction of pyrroles with nitroalkenes... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 1, 2020 Category: Molecular Biology Authors: Alessandro Palmieri Source Type: research

One-pot synthesis of β-O-4 lignin models via the insertion of stable 2-diazo-1,3-dicarbonyls into O-H bonds
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00800A, PaperRafael M. P. Dias, Gabriela Pilli, Antonio C. B. Burtoloso Lignin is a macromolecule that has received attention as a sustainable source of aromatic compounds. Due to the complex structure, the use of model substrates allows a better understanding of... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 1, 2020 Category: Molecular Biology Authors: Rafael M. P. Dias Source Type: research

Recent advances in the catalytic synthesis of 3-aminooxindoles: An update
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00777C, Review ArticleJasneet Kaur, BanniPreet Kaur, Swapandeep Singh Chimni 3-Substituted-3-aminooxindoles is a versatile scaffold and it is a common core structural motif found in many Natural products and biologically active compounds. In the last few years, the variety of... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - June 1, 2020 Category: Molecular Biology Authors: Jasneet Kaur Source Type: research

Synthesis of protected α-amino acids via decarboxylation amination from malonate derivatives
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00677G, PaperHui Fu, Peihe Li, Zheng Wang, Xiaoying Li, Qipu Dai, Changwen Hu A general and efficient strategy for the synthesis of protected α-amino acids is reported. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 29, 2020 Category: Molecular Biology Authors: Hui Fu Source Type: research

C –H functionalization of quinazolinones by transition metal catalysis
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00742K, Review ArticlePrasanjit Ghosh, Bhaskar Ganguly, Sajal Das Quinazolinone and its derivatives are an important class of heterocyclic scaffolds in pharmaceuticals and natural products. This review provides the recent research advances in the transition metal catalyzed selective C –H bond functionalization of quinazolinone. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 29, 2020 Category: Molecular Biology Authors: Prasanjit Ghosh Source Type: research

Synthesis of paenipeptin C ′ analogues employing solution-phase CLipPA chemistry
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00950D, CommunicationJuliana T. W. Tong, Iman Kavianinia, Scott A. Ferguson, Gregory M. Cook, Paul W. R. Harris, Margaret A. Brimble Thiol –ene CLipPA reaction of a vinyl ester and thiolated peptide for generation of anS-lipidated paenipeptin C ′ analogue with broad spectrum antibacterial activity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 29, 2020 Category: Molecular Biology Authors: Juliana T. W. Tong Source Type: research

Balancing Interactions in Proline-Based Receptors for Chiral Recognition of L-/D-DOPA
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00493F, PaperLin-E Guo, Yu-Xin Tang, Shu-Ying Zhang, Yuan Hong, Xiao-Sheng Yan, Zhao Li, Yun-Bao Jiang Proline based receptors (1-14) attached with phenylboronic acid and benzaldehyde bidning groups at the N-/C- or C-/N-termini of proline residue were created for chiral recognition of L-/D-DOPA, in an attempt... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 29, 2020 Category: Molecular Biology Authors: Lin-E Guo Source Type: research

Divergent synthesis of oxindole derivatives via controllable reaction of isatin-derived para-quinone methides with sulfur ylides
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00979B, Communicationyong you, Bao-Xue Quan, Zhen-Hua Wang, Jian-Qiang Zhao, Weicheng Yuan A catalyst-free and controllable reaction of isatin-derived para-quinone methides with sulfur ylides was developed. This protocol enables the divergent synthesis of two different valuable oxindole derivatives in a broad substrate... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 29, 2020 Category: Molecular Biology Authors: yong you Source Type: research

Reaction of ketone hydrazones with TeCl4: Isolation and reaction of novel divinyl telluride
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00782J, PaperKentaro Okuma, Noriyoshi Ngahora, Yuxuan Qu, Aoi Suetome Reaction of acetophenone hydrazones with TeCl4 in the presence of DBU gave a mixture of divinyl ditellurides and divinyl tellurides, which easily reacted with Cu powder in refluxing toluene to... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 29, 2020 Category: Molecular Biology Authors: Kentaro Okuma Source Type: research

Disulphide-Mediated Site-Directed Modification of Proteins
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00861C, CommunicationThorbj ørn B Nielsen, Anders Märcher, Zuzana Drobňáková, Michal Hučko, Milan Štengl, Vojtěch Balšánek, Charlotte Wiberg, Per F Nielsen, Thomas E. Nielsen, Kurt Vesterager Gothelf, Emiliano Cló Methods for chemical modification of native proteins in a controlled fashion are in high demand. Here, a novel protocol that exploits bifunctional reagents for transient targeting of solvent exposed disulphides... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Org...
Source: RSC - Organic and Biomolecular Chemistry - May 28, 2020 Category: Molecular Biology Authors: Thorbj ørn B Nielsen Source Type: research

Palladium-Catalyzed Regioselective Synthesis of B(4,5)- or B(4)-Substituted o-Carboranes Containing α,β-Unsaturated Carbonyls
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00698J, CommunicationChuyi Zhang, Qian Wang, Song Tian, Jianwei Zhang, Jiaoyi Li, Ling Zhou, Jian Lu With the help of carboxylic acid directing group, Pd-catalyzed regioselective synthesis of B(4,5)- or B(4)-substituted o-carboranes containing α,β-unsaturated carbonyls has been reported. The -COOH, removed during the course of the... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 28, 2020 Category: Molecular Biology Authors: Chuyi Zhang Source Type: research

Synthesis of quinazoin-4-ones through an acid ion exchange resin mediated cascade reaction
We report the use of 2-(2-oxazolyl)aniline to prepare quinazolin-4-one derivatives by an acid ion exchange resin mediated cascade reaction ofN-(2-(4,5-dihydrooxazol-2-yl)phenyl)benzamide for the first time. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Huiyong Yang Source Type: research

Rapid access to indole-fused bicyclo[2.2.2]octanones by merging the umpolung strategy and molecular iodine as a green catalyst
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB01038C, CommunicationTakumi Abe, Seiya Hirao We have achieved the one-pot construction of otherwise more difficult to access indole-fused bicyclo[2.2.2]octanones by merging the umpolung strategy and molecular iodine catalyst. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Takumi Abe Source Type: research

Photochemical [2 + 2] cycloaddition reaction of carbonyl compounds with Danishefsky diene
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00921K, PaperDian Agung Pangaribowo, Manabu Abe An efficient oxetane formation has been developed in the photochemical [2 + 2] cycloaddition reaction of benzophenone with Danishefsky diene. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Dian Agung Pangaribowo Source Type: research

Differential scanning fluorimetry (DSF) screen to identify inhibitors of Hsp60 protein –protein interactions
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00928H, CommunicationHao Shao, Keely Oltion, Taia Wu, Jason E. Gestwicki Homo-oligomers are difficult drug targets. Here, Differential Scanning Fluorimetry (DSF) is introduced as a method to identify inhibitors of these systems, by discriminating between oligomers and monomers based on their thermal stability. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Hao Shao Source Type: research

Synthesis of Type 1 Lewis b hexasaccharide antigen structures featuring flexible incorporation of L-[U-13C6]-fucose for NMR binding studies
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00426J, PaperMark Bryan Long, Aisling N í Cheallaigh, Mark Reihill, Stefan Oscarson, Martina Lahmann While13C-labelled proteins are common tools in NMR studies, lack of access to13C-labelled carbohydrate structures has restricted their use. L-fucose is involved in a wide range of physiological and... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Mark Bryan Long Source Type: research

Organocatalytic enone-azide [3+2]-cycloaddition: synthesis of functionally rich C/N-double vinyl 1,2,3-triazoles
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00848F, PaperRamachary Buchi Dhevalapally, Surendra Reddy G., Suresh Kumar Adaveni An enolate-mediated organocatalytic [3+2]-cycloaddition of enones with less reactive vinyl/alkyl/aryl azides is reported at the room temperature for shorter reaction times. The metal-free amine-mediated catalytic conditions of this [3+2]-cycloaddition allowed... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Ramachary Buchi Dhevalapally Source Type: research

One-pot synthesis of porphyrin-based [5]rotaxanes
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00906G, PaperPablo Martinez Bulit, Benjamin H Wilson, Stephen J Loeb A one-pot reaction is used to make a series of [5]rotaxanes. The protocol involves simultaneous threading-followed-by-stoppering to trap a macrocycle (dibenzo[24]crown 8, DB24C8) on an axle to form a mechanically... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Pablo Martinez Bulit Source Type: research

Site-selective modification of proteins using cucurbit[7]uril as supramolecular protection for N-terminal aromatic amino acids
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB01004A, CommunicationAnton A. A. Smith, Caitlin L. Maikawa, Gillie A. Roth, Eric A. Appel Supramolecular protection ofN-terminal aromatic amino acids through complexation with cucurbit[7]uril can enable site-selective protein modification of unfavored motifs. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Anton A. A. Smith Source Type: research

Synthesis of Proteasome Inhibitor 6-Deoxy-Omuralide and Its Enantiomer Using Stereoselective Alkylation of Substituted Proline Ester
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB01053G, PaperFeng Li, Voker J äger A potent 20S proteasome inhibitor, 6-deoxy-omuralide was stereoselectively synthesized in 20 steps with 5.1% overall yield staring from a chiral boron agent and D-glyceraldehyde acetonide. The stereoselective alkylation of the... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Feng Li Source Type: research

Characterization in Aqueous Medium of an FMN Semiquinone Radical Stabilized by the Enzyme-Like Microenvironment of a Modified Polyethyleneimine
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00864H, CommunicationYoan Chevalier, Yvette Lock Toy Ki, Christian Herrero, Didier Le Nouen, Jean-Pierre Mahy, Jean-Philippe Goddard, Fr édéric Avenier The elusive flavin semiquinone intermediate found in flavoproteins such as cryptochromes has been obtained in aqueous solution by single electron reduction of the natural FMN cofactor using sodium ascorbate. This... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Yoan Chevalier Source Type: research

P(NMe2)3 mediated cyclopropanation of α-methylene-β-lactams for rapid syntheses of spirocyclopropyl β-lactams
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00826E, PaperSi-qin Luo, Wei Liu, Banfeng Ruan, Shilu Fan, Huixia Zhu, Wei Tao, Hua Xiao An expedient cyclopropanation of α-methylene-β-lactams with α-keto esters mediated by P(NMe2)3 has been developed. This reaction enables rapid access to a series of functionalized spirocyclopropyl β-lactams in good yields from... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Si-qin Luo Source Type: research

Stereoselective Synthesis of 2,6-Disubstituted Piperidine Alkaloids
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00918K, Review ArticleNikhil Srivastava, LINGAMURTHY MACHA, Hyun-Joon Ha Among the large number of structurally diverse alkaloids, 2,6-disubstituted piperidine and its analogs have often been targeted when exploiting new synthetic techniques perhaps because of their strong pharmacological properties. This... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Nikhil Srivastava Source Type: research

Palladium Catalyzed Asymmetric Allylic Alkylation of Isoquinolinedione Derivatives in the Preparation of Quaternary Carbon Stereocenter
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00765J, CommunicationYingxian Li, CHENG CHENG, Lei Tang, YUAN-YONG YANG A highly enantioselective allylic alkylation of isoquinolinedione derivatives under palladium catalysis was developed in the preparation of quaternary carbon stereocenter. Under standard reaction conditions excellent yields and enantioselectivities were realized... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 27, 2020 Category: Molecular Biology Authors: Yingxian Li Source Type: research

Modular control of L-tryptophan isotopic substitution via an efficient biosynthetic cascade
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00868K, CommunicationClayton M. Thompson, Allwin D. McDonald, Hanming Yang, Silvia Cavagnero, Andrew R. Buller Facile biocatalytic synthesis of isotopically substituted tryptophans. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 26, 2020 Category: Molecular Biology Authors: Clayton M. Thompson Source Type: research

Pyrrole-based anion-responsive π-electronic molecules as fluorescence sensors responsive to multiple stimuli
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00952K, PaperShinya Sugiura, Hiromitsu Maeda Introduction of electron-donating N,N-dimethylaminophenyl groups in dipyrrolyldiketone BF2 complexes as anion-responsive π-electronic molecules resulted in fascinating fluorescence properties. The fluorescence properties, which depended on the degree of photo-induced electron transfer,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 26, 2020 Category: Molecular Biology Authors: Shinya Sugiura Source Type: research

Synthesis of Paenipeptin C ʹ Analogues Employing Solution-Phase CLipPA Chemistry
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00950D, CommunicationMargaret A Brimble, Juliana Tong, Iman Kavianinia, Scott A. Ferguson, Greg Cook, Paul Harris We herein report the synthesis of analogues of the antimicrobial lipopeptide, paenipeptin C ˊ, by installing varying lipid moieties using thiol-ene CLipPA (Cysteine Lipidation on a Peptide or Amino Acid) chemistry.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 26, 2020 Category: Molecular Biology Authors: Margaret A Brimble Source Type: research

Remote C –C bond formation via visible light photoredox-catalyzed intramolecular hydrogen atom transfer
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00854K, Review ArticleHui Chen, Shouyun Yu Carbon-carbon bonds comprise major framework of organic molecules, rendering their formation one of the most fundamental transformations in synthetic organic chemistry. Visible light photoredox catalysis has recently been established as... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 26, 2020 Category: Molecular Biology Authors: Hui Chen Source Type: research

Synthesis of aryl ethers of carbohydrates via reaction with arynes: selective O-arylation of trans-vicinal dihydroxyl groups in carbohydrates
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00540A, CommunicationMonika Bhardwaj, Nazar Hussain, Irshad Ahmad Zargar, Ashutosh K. Dash, Debaraj Mukherjee A new method for theO-arylation of carbohydrates under transition metal-free conditions using arynes as an aryl source has been developed. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 23, 2020 Category: Molecular Biology Authors: Monika Bhardwaj Source Type: research

Experimental and theoretical study on the cyclic(alkyl)(amino)carbene-copper catalyzed Friedel –Crafts reaction of N,N-dialkylanilines with styrenes
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/C9OB02734C, PaperWentao Ma, Gaowen Zhai, Xingbang Hu, Youting Wu The Friedel –Crafts reaction of alkalinous substrates is achieved using a copper based catalyst. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 23, 2020 Category: Molecular Biology Authors: Wentao Ma Source Type: research

Hydrogen-bonding-assisted redox-neutral construction of tetrahydroquinolines via hydride transfer
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00521E, PaperXiaoyu Yang, Fangzhi Hu, Liang Wang, Lubin Xu, Shuai-Shuai Li The hydrogen-bonding-assisted construction of tetrahydroquinolines decorated with structurally diverse 3,3 ′-difunctional groups has been realizedvia a hydride transfer-involved three-step cascade reaction in the presence of morpholine. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 23, 2020 Category: Molecular Biology Authors: Xiaoyu Yang Source Type: research

Correction: Asymmetric synthesis of ( −)-solanidine and (−)-tomatidenol
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Yun Wang, Guanxin Huang, Yong Shi, Wei-sheng Tian, Chunlin Zhuang, Fen-Er Chen To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 23, 2020 Category: Molecular Biology Authors: Yun Wang Source Type: research

Novel use of 2-BTSO2CF2H for the metal-free electrophilic difluoromethylthiolation of indoles
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00872A, CommunicationJun Wei, Kun Bao, Yuan Wang, Rong Sheng, Jinbo Hu Electrophilic difluoromethylthiolation of indoles with 2-BTSO2CF2H has been conducted. In the presence of (EtO)2P(O)H and TMSCl, the reaction proceeded in modest to high yields under mild conditions. This is an... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 22, 2020 Category: Molecular Biology Authors: Jun Wei Source Type: research

Understanding the Structures and Aromaticity of Heteroporphyrins with Computations
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00656D, PaperXiaoli Fang, Xiahe Chen, Qunmin Wang, Yun-Fang Yang, Yuan-Bin She Heteroporphyrins are the porphyrin derivatives with replacement of the pyrrolic NH moiety by other heteroatom-containing groups, such as PH, AsH, SiH2, O, S, etc. For all studied heteroporphyrins, the macrocycle... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 22, 2020 Category: Molecular Biology Authors: Xiaoli Fang Source Type: research

A novel one-pot method for the stereoselective synthesis of tetrahydropyrimidinones in a low melting mixture
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00697A, CommunicationPramila Devi, Mallikharjuna Rao Lambu, Sundarababu Baskaran A metal free method for the stereoselective synthesis of tetrahydropyrimidinone from a vinyl arene has been developed using a low melting mixture as a novel reaction medium. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Pramila Devi Source Type: research

Asymmetric N-aminoalkylation of 3-substituted indoles by N-protected N,O-acetals: an access to chiral propargyl aminals
Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00795A, CommunicationJunxian Yang, Zeyuan He, Liang Hong, Wangsheng Sun, Rui Wang A direct enantioselective N1 aminoalkylation of 3-substituted indoles is efficiently catalyzed by a phosphoric acid catalyst under mild conditions, which could be applied to the modification of tryptophan containing oligopeptides. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Junxian Yang Source Type: research

Synthesis of unsymmetrical disulfides via PPh3-mediated reductive coupling of thiophenols with sulfonyl chlorides
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00804D, PaperDungai Wang, Xiao Liang, Mingteng Xiong, Heping Zhu, Yifeng Zhou, Yuanjiang Pan A facile and rapid synthesis of unsymmetrical aryl disulfides using PPh3-mediated reductive coupling of thiophenols with aryl sulfonyl chlorides was described. Good functional group tolerance and scalability were achieved in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Dungai Wang Source Type: research

Photochemical [2+2] Cycloaddition Reaction of Carbonyl Compounds with Danishefsky Diene
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00921K, PaperManabu Abe, Dian Agung Pangaribowo Danishefsky diene, trans-1-methoxy-3-trimethylsilyloxy-buta-1,3-diene, has been utilized in organic synthesis in thermal reactions for a long time. The purpose of this study is to investigate the photochemical reaction of ketones with... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Manabu Abe Source Type: research

Enantioselective Synthesis Enabled by Visible Light Photocatalysis
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00759E, Review ArticleBor-Cherng Hong Enantioselective photoreactions have been synthetic challenge for decades. With the continuous development of modern visible light photocatalysis and asymmetric catalysis, remarkable advances have been achieved through the synergistic action of... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Bor-Cherng Hong Source Type: research

C-H Functionalization of Quinazolinone by Transition Metal Catalysis
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00742K, Review ArticlePrasanjit Ghosh, Bhaskar Ganguly, Sajal Das Quinazolinone and its congeners are ubiquitous structural motifs found in numerous natural products due to their wide application as anticancer, antiviral, anti-inflammatory, antifloate and antitumor agents etc. Previously, synthetic community... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Prasanjit Ghosh Source Type: research

Differential Scanning Fluorimetry (DSF) Screen to Identify Inhibitors of Hsp60 Protein-Protein Interactions
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00928H, CommunicationHao Shao, Keely Oltion, Taia Wu, Jason E. Gestwicki There are relatively few methods available for discovering inhibitors of the protein-protein interactions (PPIs) that hold together homo-oligomers. We envisioned that Differential Scanning Fluorimetry (DSF) might be a versatile way... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Hao Shao Source Type: research

Rapid access to indole-fused bicyclo[2.2.2]octanones by merging umpolung strategy and molecular iodine as a green catalyst
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB01038C, CommunicationTakumi Abe, Seiya Hirao One-pot synthesis of indole-fused bicyclo[2.2.2]octanones from DiMeOIN and 2-cyclohexen-1-one are accomplished under iodine catalyst. This simple and metal-free conditions provides a practical tool to construct Csp3-rich complex molecules via oxidative... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Takumi Abe Source Type: research

Palladium-catalyzed Asymmetric Dearomative Cyclization in Natural Product Synthesis
Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/D0OB00818D, Review ArticleZhuo Wang Asymmetric catalysis is a rapidly growing field in modern organic chemistry and has been indispensable for the synthesis of enantioenriched materials to meet demands from the academies to pharmaceutical industries.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - May 21, 2020 Category: Molecular Biology Authors: Zhuo Wang Source Type: research