RSC - Organic and Biomolecular Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
Visible-light-induced C –S bond formation in the synthesis of 2,4-disubstituted thiazoles through cascade difunctionalization of acetophenone: a greener approach
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00096J, PaperKhushbu Rajput, Vishal Singh, Priya Mahaur, Sundaram Singh, Vandana Srivastava A novel approach for the synthesis of 2,4-disubstituted thiazoles from methyl aryl ketones,N-bromo-succinimide (NBS), and thioamide in water as a green reaction medium through visible-light irradiation is reported. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 18, 2024 Category: Molecular Biology Authors: Khushbu Rajput Source Type: research
Recent advances in spirocyclization of maleimides via transition-metal catalyzed C –H activation
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D3OB01904G, Review ArticleSwadhin Swaraj Acharya, Sagarika Patra, Rojalini Maharana, Manaswini Dash, Liza Mama Barad, Bibhuti Bhusan Parida In recent years, the maleimide scaffold has received a great deal of attention in C –H activation. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 18, 2024 Category: Molecular Biology Authors: Swadhin Swaraj Acharya Source Type: research
Hydrosilylation of nitriles and tertiary amides using a zinc precursor
We report the competent and selective hydrosilylation of nitriles and tertiary amides catalyzed by readily available zinc bis(hexamethyldislazide) under solvent-free and mild conditions, making it a sustainable and desirable alternative... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 18, 2024 Category: Molecular Biology Authors: Tarun K. Panda Source Type: research
Biosynthesis of a new skyllamycin analogue in Streptomyces nodosus: a cytochrome P450 forms an epoxide in the cinnamoyl chain
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Yuhao Song, Jose Amaya, Vidhi C Murarka, Hugo Mendez, Mark Hogan, jimmy muldoon, Paul Evans, Yannick Ortin, Steven Kelly, David Lamb, Thomas Poulos, Patrick Caffrey Activation of a silent gene cluster in Streptomyces nodosus leads to synthesis of a cinnamoyl-containing non-ribosomal peptide (CCNP) that is related to skyllamycins. This novel CCNP was isolated and its... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 18, 2024 Category: Molecular Biology Authors: Yuhao Song Source Type: research
Visible Light-induced Metal-free Cascade Denitrogenative Boryla-tion and Iodination of Nitroarenes
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00309H, PaperFanglin Zhang, JunWei Li, Tian-Shun Duan, Bing Sun An efficient method was developed for one-pot construction of C ‒B and C‒I via visible light-induced transformation from nitroarenes. This protocol relies on the photochemical property of nitroarenes under visible light,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: Fanglin Zhang Source Type: research
Identification of BACE-1 inhibitors through directed C(sp3) –H activation on 5-oxo-pyrrolidine-3-carboxylic acid derivatives
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Lorenzo Baldini, Elena Lenci, Cristina Faggi, Andrea Trabocchi Stereochemically dense 5-oxo-pyrrolidines were obtained by combining the Castagnoli –Cushman reaction with directed Pd-catalyzed C(sp3) –H functionalization and enabling the identification of two BACE-1 enzyme inhibitors with sub-micromolar activity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: Lorenzo Baldini Source Type: research
Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermo-stability and yield
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00211C, Paperyuke cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo Zheng The catalytic activity is undoubtedly a key focus in enzyme engineering, whereas the complicated reaction conditions hindered some enzymes from industrialization, although they have a relative promising activity. This happened... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: yuke cen Source Type: research
Mutasynthesis Generates Nine New Pyrroindomycins
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00239C, PaperZhuhua Wu, Zhengxiang Xia, Zhijun Tang, Ji ’an Li, Wen Liu Pyrroindomycins (PYRs) represent the only spirotetramate natural products discovered in nature, which possess potent activities against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. Their unique structure and impressive biological activities... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: Zhuhua Wu Source Type: research
Identification of reaction sites and chlorinated products of purine bases and nucleosides during chlorination: a computational study
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D3OB02111D, PaperFuhao Zhang, Yonghang Mo, Xiaomin Cao, Yingying Zhou, Yongdong Liu, ru-gang zhong Hypochlorous acid (HOCl) released from activated leukocytes plays a significant role in the human immune system, but also implicates in numerous diseases due to its inappropriate production. Chlorinated nucleobases induce... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: Fuhao Zhang Source Type: research
Selective synthesis of an elusive C-functionalized bis-cyclam through the bis-aminal route and study of its inhibition properties of CXCR4 chemokine receptor
This article presents the controlled synthesis of a rare example of C,C ’-linked bis-cyclam architecture in mild conditions through to the “bis-aminal” route, previously used for the advantageous synthesis of cyclam,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: Marie M Le Roy Source Type: research
Overview of alkyl quercetin lipophenol synthesis and its protective effect against carbonyl stress involved in neurodegeneration
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.L éa Otaegui, Jordan Lehoux, Leo Martin, Laurent Givalois, Thierry Durand, Catherine Desrumaux, Céline Crauste Oxidative stress, and carbonyl stress resulting from the toxicity of small aldehydes, are part of detrimental mechanisms leading to neuronal cell loss involved in the progression of neurodegenerative diseases such... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: L éa Otaegui Source Type: research
Phenyliodine bis(trifluoroacetate) as a Sustainable Reagent: Exploring Its Significance in Organic Synthesis
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D3OB01964K, Review ArticleSunil Kumar Singh, Sumit Kumar, Aditi Arora, Rajesh Kumar, Bhawani Shankar, Brajendra Kumar Singh Iodine-containing molecules have garnered substantial attention in the realm of organic synthesis during recent decades. Higher oxidation state iodine compounds, often denoted as 'hypervalent iodine compounds,' have proven to be... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: Sunil Kumar Singh Source Type: research
Asymmetric synthesis of the fully functionalized six-membered A-ring of siphonol A
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00104D, CommunicationYing Sun, Shaomin Fu, Bo Liu The asymmetric synthesis of the fully functionalized six-membered A-ring of siphonol A is presented. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 14, 2024 Category: Molecular Biology Authors: Ying Sun Source Type: research
Correction and removal of expression of concern: Total synthesis of tubulysin U and N14-desacetoxytubulysin H
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Bohua Long, Cheng Tao, Yinghong Li, Xiaobin Zeng, Meiqun Cao, Zhengzhi Wu To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 14, 2024 Category: Molecular Biology Authors: Bohua Long Source Type: research
A Ni0(cod)(dq) (COD: 1,5-cycloctadiene; DQ: duroquinone) complex as a catalyst precursor for oligothiophene and polythiophene synthesis
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00210E, PaperNaoki Noda, Seiha Yamaoka, Ukyo Ogi, Masaki Horie, Kentaro Okano, Atsunori Mori Ni(cod)(dq) effectively serves as a catalyst precursor for the preparation of well-defined oligothiophenes and polythiophenes. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 14, 2024 Category: Molecular Biology Authors: Naoki Noda Source Type: research