RSC - Organic and Biomolecular Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Visible light-induced metal-free cascade denitrogenative borylation and iodination of nitroarenes
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00309H, PaperJun-Wei Li, Tian-Shun Duan, Bing Sun, Fang-Lin Zhang A simple, efficient, green method for converting nitroarenes into haloarenes and arylboronates under light irradiation. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 22, 2024 Category: Molecular Biology Authors: Jun-Wei Li Source Type: research

Biosynthesis of a new skyllamycin in Streptomyces nodosus: a cytochrome P450 forms an epoxide in the cinnamoyl chain
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Yuhao Song, Jose A. Amaya, Vidhi C. Murarka, Hugo Mendez, Mark Hogan, Jimmy Muldoon, Paul Evans, Yannick Ortin, Steven L. Kelly, David C. Lamb, Thomas L. Poulos, Patrick Caffrey Gene disruption identifies a class of cytochrome P450s that form epoxides in acyl chains of substituted cinnamoyl-containing natural products. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 22, 2024 Category: Molecular Biology Authors: Yuhao Song Source Type: research

Diversity-oriented synthesis of indole-fused scaffolds and bis(indolyl)methane from tosyl-protected tryptamine
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00099D, PaperLiang Wang, Xiaopei Song, Fengxia Guo, Lubin Xu, Fangzhi Hu, Feng-Wei Guo, Shuai-Shuai Li Diversity-oriented synthesis of indole-1,2-fused 1,4-benzodiazepines, tetrahydro- β-carbolines, and 2,2′-bis(indolyl)methanes is presented by control of reaction sites. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 22, 2024 Category: Molecular Biology Authors: Liang Wang Source Type: research

Unusual immunosuppressive pyridine-containing, bisnor- (c23), tetranor- (c21) and pentanor- (c20) sesterterpenoids from Tibetan Leucosceptrum canum
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00334A, PaperMan Li, Ling Feng, Han Zhang, Yan-Chun Liu, Ting-Ting Zhou, Yu Zheng, Kai Guo, Yan Liu, Sheng-Hong Li An unusual pyridine-containing sesterterpenoid, leucosceptrodine (1), and five new nor-leucosceptrane sesterterpenoids including bisnor- (C23, 2), tetranor- (C21, 3) and pentanor- (C20, 4 −6) skeletons, were isolated from the leaves of Tibetan... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 22, 2024 Category: Molecular Biology Authors: Man Li Source Type: research

Phosphamide nucleotide analog: A substrate for polymerase synthesis of DNA
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00089G, CommunicationJiong Meng, Qiaqia Guo, Xiaona Zhai, Song Yang, Shuai Wang, Pengcheng Wang, Debin Ji A type of modified nucleotide, deoxynucleotide γ-amidotriphosphates (dNTPγNH2s), exhibited around five times higher stability than that of dNTPs. These phosphamide nucleotides can be utilized by several DNA polymerases, and the... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 22, 2024 Category: Molecular Biology Authors: Jiong Meng Source Type: research

Synthesis of alkynyl sulfides via base-promoted nucleophilic ring-opening of α-bromostyrene sulfonium salt
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00203B, CommunicationJian Wen, Ziyu Wang, Junqi Zhou, Hanmiao Xu, Mengke Su An efficient method for the synthesis of alkynyl sulfides via C(sp3) −S bond cleavage of α-bromostyrene sulfonium salts has been developed. This base-promoted nucleophilic ring-opening pathway that allows for the preparation... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 22, 2024 Category: Molecular Biology Authors: Jian Wen Source Type: research

Photogenerated chlorine radical activates C(sp3) –H bonds of alkylbenzenes to access quinazolinones
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00129J, CommunicationXin-Yao Pan, sun guixia, huang fangping, Wen-Jian Qin, Qinghu Teng, Kai Wang A Fe-catalyzed visible-light induced condensation of alkylbenzenes with anthranilamides has been developed. Upon irradiation, the trivalent iron complex could generate chlorine radical, which successfully abstracted hydrogen of benzylic C –H bonds... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 21, 2024 Category: Molecular Biology Authors: Xin-Yao Pan Source Type: research

Synthesis of difluoromethylated spiropyrazolones via [3 + 2] cycloaddition of difluoroacetohydrazonoyl bromides with alkylidene pyrazolones
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00044G, PaperYang Feng, Yuanyuan Ren, Duoduo Tang, Ke-Hu Wang, Junjiao Wang, Danfeng Huang, Xiaobo Lv, Yulai Hu Highly functionalized fluoroalkyl spiropyrazolones are synthesizedvia an effective [3 + 2] cycloaddition of di/trifluoromethyl hydrazonoyl bromides and alkylidene pyrazolones in good yields. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 20, 2024 Category: Molecular Biology Authors: Yang Feng Source Type: research

Expanding the scope of the Successive Ring Expansion strategy for macrocycle and medium-sized ring synthesis: unreactive and reactive lactams
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Zhongzhen Yang, Marion Arnoux, Damien Hazelard, Owen Hughes, Joe Nabarro, Adrian Charles Whitwood, Martin A Fascione, Christopher D. Spicer, Philippe Compain, William Paul Unsworth New methods are described that expand the scope of the Successive Ring Expansion (SuRE) with respect to synthetically challenging lactams. A protocol has been developed for use with ‘unreactive’ lactams,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 20, 2024 Category: Molecular Biology Authors: Zhongzhen Yang Source Type: research

Pd(II)-catalyzed cascade annulation of N-substituted anilines with CO, NH4OAc and aldehydes to N1-substituted 2,3-dihydroquinazolin-4(1H)-ones
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00055B, PaperXiaopeng Zhang, Qiuyang Pang, Dan Liu, Zhenhua Guo, Guisheng Zhang N1-substituted 2,3-dihydroquinazolin-4(1H)-ones have been synthesizedvia Pd-catalyzed annulation ofN-substituted anilines with CO, NH4OAc and aldehydes, and the reaction features simple raw materials, high step economy, and good product diversity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 20, 2024 Category: Molecular Biology Authors: Xiaopeng Zhang Source Type: research

Albumin-ruthenium catalyst conjugate for bio-orthogonal uncaging of alloc group
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00234B, PaperKimberly S Taylor, Madison M McMonagle, Schaelee C Guy, Ariana M Human-McKinnon, Shumpei Asamizu, Heidi J Fletcher, Bradley W Davis, Takashi Leo Suyama The employment of antibodies as a targeted drug delivery vehicle has proven successful which is exemplified by the emergence of antibody-drug conjugates (ADCs). However, ADCs are not without their shortcomings.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 20, 2024 Category: Molecular Biology Authors: Kimberly S Taylor Source Type: research

A chloromethyl-triazole fluorescent chemosensor for O6-methylguanine DNA methyltransferase
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00120F, CommunicationSeylan Ayan, Adrian M. Rotaru, Esther G. Kaye, Gabrielle Juneau, Sunit Das, Christopher J. Wilds, Andrew A. Beharry A fluorescent chemosensor for O6-methylguanine DNA methyltransferase derived from a non-pseudosubstrate, covalent inhibitor. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 20, 2024 Category: Molecular Biology Authors: Seylan Ayan Source Type: research

Weakly acidic pH-responsive liposomal content release induced by histidine-modified agents
In this study, to enhance the endosomal pH control of drug release from... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 19, 2024 Category: Molecular Biology Authors: Ayumi Kashiwada Source Type: research

Iodide-umpolung catalytic system for non-traditional amide coupling from nitroalkanes and amines
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00184B, PaperChun-Lin Chen, Tian-Sih Huang, Po-Hsiang Chang, Che-Sheng Hsu Developing a new catalytic system involves reversing the polarity (umpolung) concept to synthesize amide derivatives. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 18, 2024 Category: Molecular Biology Authors: Chun-Lin Chen Source Type: research

Visible-light-induced C –S bond formation in the synthesis of 2,4-disubstituted thiazoles through cascade difunctionalization of acetophenone: a greener approach
Org. Biomol. Chem., 2024, Advance Article DOI: 10.1039/D4OB00096J, PaperKhushbu Rajput, Vishal Singh, Priya Mahaur, Sundaram Singh, Vandana Srivastava A novel approach for the synthesis of 2,4-disubstituted thiazoles from methyl aryl ketones,N-bromo-succinimide (NBS), and thioamide in water as a green reaction medium through visible-light irradiation is reported. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 18, 2024 Category: Molecular Biology Authors: Khushbu Rajput Source Type: research