Microwave ‐Induced Structural Engineering and Pt Trapping in 6R‐TaS2 for the Hydrogen Evolution Reaction
6R‐TaS2 is newly discovered as electrocatalyst for the hydrogen evolution reaction, investigating its exfoliated 2D forms, microwave ‐induced structural engineering, and Pt trapping effects. AbstractThe nanoengineering of the structure of transition metal dichalcogenides (TMDs) is widely pursued to develop viable catalysts for the hydrogen evolution reaction (HER) alternative to the precious metallic ones. Metallic group ‐5 TMDs have been demonstrated to be effective catalysts for the HER in acidic media, making affordable real proton exchange membrane water electrolysers. Their key‐plus relies on the fact that bot...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Leyla Najafi, Sebastiano Bellani, Reinier Oropesa ‐Nuñez, Rosaria Brescia, Mirko Prato, Lea Pasquale, Cansunur Demirci, Filippo Drago, Beatriz Martín‐García, Jan Luxa, Liberato Manna, Zdeněk Sofer, Francesco Bonaccorso Tags: Full Paper Source Type: research

Stabilizing γ‐CsPbI3 Perovskite via Phenylethylammonium for Efficient Solar Cells with Open‐Circuit Voltage over 1.3 V
By introducing moderate phenylethylammonium iodide and lead acetate in CsPbI3 perovksite, moiture resistance and charge recombination are optimized. The device achieves a 17% power conversion efficiency, a 1.33 V open ‐circuit voltage (VOC) and the smallest 0.38 VVOC deficit. Meanwhile, the device maintains 94% of its efficiency after 2000 h storage in ambient environment. AbstractCesium lead iodide (CsPbI3) perovskite has gained great attention due to its potential thermal stability and appropriate bandgap (≈1.73  eV) for tandem cells. However, the moisture‐induced thermodynamically unstable phase and large...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Qiufeng Ye, Fei Ma, Yang Zhao, Shiqi Yu, Zema Chu, Pingqi Gao, Xingwang Zhang, Jingbi You Tags: Communication Source Type: research

Bioinspired Functional Black Phosphorus Electrospun Fibers Achieving Recruitment and Biomineralization for Staged Bone Regeneration
A bioinspired bone morphogenetic protein2 (BMP2) ‐modified black phosphorus (BP) electrospun fiber with staged bone regeneration properties via recruiting osteoblast precursor cells to the bone injured site and accelerating biomineralization are developed for effectively promoting critical cranial defect physiological regeneration. BP could not only provide a negative surface and a strong BMP2 loading ability but also promote biomineralization in electrospun fibrous scaffold. AbstractThe ideal bone repair material should firstly recognize and recruit osteoblast precursor cells to initiate the repair process, then promote...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Liang Cheng, Zhijie Chen, Zhengwei Cai, Jingwen Zhao, Min Lu, Jing Liang, Fei Wang, Jin Qi, Wenguo Cui, Lianfu Deng Tags: Full Paper Source Type: research

Subcompartmentalization and Pseudo ‐Division of Model Protocells
An autonomous subcompartmentalization mechanism is reported for protocells which results in the transformation of initial subcompartments to daughter protocells. The process is solely determined by the fundamental materials properties and interfacial events. Similar events may have taken place under early Earth conditions, leading to the development of compartmentalized cells and potentially, primitive division. AbstractMembrane enclosed intracellular compartments have been exclusively associated with the eukaryotes, represented by the highly compartmentalized last eukaryotic common ancestor. Recent evidence showing the pr...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Karolina Spustova, Elif Senem K öksal, Alar Ainla, Irep Gözen Tags: Full Paper Source Type: research

Advances in Multidimensional Cardiac Biosensing Technologies: From Electrophysiology to Mechanical Motion and Contractile Force
This review focuses on the recent advances of biosensing technologies for the 2D and 3D cardiac models with three special properties: electrophysiology, mechanical motion, and contractile force. Moreover, the characteristics, advantages, limitations, and applications of these cardiac biosensing technologies, as well as the future development prospects are also introduced and discussed. AbstractCardiovascular disease is currently a leading killer to human, while drug ‐induced cardiotoxicity remains the main cause of the withdrawal and attrition of drugs. Taking clinical correlation and throughput into account, cardiomyocy...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Xinwei Wei, Liujing Zhuang, Hongbo Li, Chuanjiang He, Hao Wan, Ning Hu, Ping Wang Tags: Review Source Type: research

Transition Metal and Metal –Nx Codoped MOF‐Derived Fenton‐Like Catalysts: A Comparative Study on Single Atoms and Nanoparticles
The Fenton ‐like catalytic activities and efficiencies of Co‐based nanoparticles and single‐atom structures are investigated and compared systematically via engineering catalysts comprising Co‐nanocrystals and atomic Co–Nx codoped carbon nanotubes. Benefiting from the maximized atomic utilization, the atomic Co –Nx centers exhibit much higher reaction kinetic constant and mass activity toward the degradation of bisphenol A, far exceeding the Co nanoparticles. AbstractTo deal with the ever ‐growing toxic benzene‐derived compounds in the water system, extensive efforts have been dedicated for catalyti...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Yun Gao, Chengdong Yang, Mi Zhou, Chao He, Sujiao Cao, Yanping Long, Shuang Li, Yi Lin, Puxin Zhu, Chong Cheng Tags: Full Paper Source Type: research

Elucidating Influence of Mg ‐ and Cu‐Doping on Electrochemical Properties of O3‐Nax[Fe,Mn]O2 for Na‐Ion Batteries
O3 ‐Na5/6Fe1/3Mn1/2Mg1/6O2 is newly synthesized which delivers a high capacity of 196 mAh g−1 and is applicable to hard carbon // O3 ‐Na5/6Fe1/3Mn1/2Mg1/6O2 Na ‐ion cell. In addition to Mn3+/4+ and Fe3+/4+ redox, oxide ions participate in solid ‐state redox. Furthermore, randomly stacked intergrowth phases based on the ideal OP2‐type phase reversibly appear during sodium insertion and extraction. AbstractAlthough O3 ‐NaFe1/2Mn1/2O2 delivers a large capacity of over 150 mAh g−1 in an aprotic Na cell, its moist ‐air stability and cycle stability are unsatisfactory for practical use. Slightly Na‐de...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Yusuke Yoda, Kei Kubota, Kazutoshi Kuroki, Shinya Suzuki, Keisuke Yamanaka, Toyonari Yaji, Shota Amagasa, Yasuhiro Yamada, Toshiaki Ohta, Shinichi Komaba Tags: Full Paper Source Type: research

Laser Writable Multifunctional van der Waals Heterostructures
Herein, a facile, fast, and versatile laser direct write micro/nanoprocessing technique is utilized to achieve multifunctional nanoelectronic devices (PN diode, NPN, and PNP bipolar junction transistor (BJT)) simultaneously based on one 2D material heterostructure. The current gain of the BJT can be modulated efficiently by the laser writing tunable base width. AbstractAchieving multifunctional van der Waals nanoelectronic devices on one structure is essential for the integration of 2D materials; however, it involves complex architectural designs and manufacturing processes. Herein, a facile, fast, and versatile laser dire...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Bao ‐Wang Su, Xi‐Lin Zhang, Bin‐Wei Yao, Hao‐Wei Guo, De‐Kang Li, Xu‐Dong Chen, Zhi‐Bo Liu, Jian‐Guo Tian Tags: Full Paper Source Type: research

Unexpected Photoinduced Room Temperature Magnetization in Bi2WO6 Nanosheets
The ultraviolet (UV) ‐illumination of the hydrothermally prepared Bi2WO6 nanosheets promotes a yellow ‐green color change and significantly enhanced magnetic signals (saturated magnetization (Ms) increases from 0.002 to 0.12 emu g−1). X ‐ray photoelectron spectroscopy (XPS) results show unexpected W reduction (W6+ to W5+/W4+) and Bi oxidation (Bi3+ to Bi5+) upon UV illumination for the Bi2WO6 nanosheets, indicating a photoexcited Bi to W charge transfer. AbstractThe current investigation in magnetism in 2D materials offers new opportunities for studying spintronics at low dimensions. Here, reversible photoinduc...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Jing Wei, Yuguo Xia, Abdul Qayum, Xiuling Jiao, Dairong Chen, Ting Wang Tags: Full Paper Source Type: research

Hierarchical Structures, with Submillimeter Patterns, Micrometer Wrinkles, and Nanoscale Decorations, Suppress Biofouling and Enable Rapid Droplet Digitization
Hierarchical liquid repellant surfaces suppressing blood adhesion and clot formation, are fabricated though scalable solution ‐based methods. Patterning hydrophilic regions within the liquid repellant surface provide a rapid compartmentalization of solutions into virtual wells. This can be translated into rapid, dip‐based biosensing assays with droplet digitization. AbstractLiquid repellant surfaces have been shown to play a vital role for eliminating thrombosis on medical devices, minimizing blood contamination on common surfaces as well as preventing non ‐specific adhesion. Herein, an all solution‐based, easily s...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Sara M. Imani, Roderick Maclachlan, Yuting Chan, Amid Shakeri, Leyla Soleymani, Tohid F. Didar Tags: Full Paper Source Type: research

Nanoscale Imaging and Control of Volatile and Non ‐Volatile Resistive Switching in VO2
Herein, in opernado X ‐ray nanoimaging is used to follow the evolution of the nanostructure and defect concentration in Mott insulator VO2 during an electrically driven transition. By temporarily inducing the crystal lattice disorder, the switching response of individual nanodomains between volatile and persistent modalities is reversibly modified. This is an important step toward emulating neurons and synapses in a neuromorphic implementation. AbstractControl of the metal ‐insulator phase transition is vital for emerging neuromorphic and memristive technologies. The ability to alter the electrically driven transition ...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Anatoly G. Shabalin, Javier Valle, Nelson Hua, Mathew J. Cherukara, Martin V. Holt, Ivan K. Schuller, Oleg G. Shpyrko Tags: Communication Source Type: research

Fluorine Triggered Surface and Lattice Regulation in Anatase TiO2 −xFx Nanocrystals for Ultrafast Pseudocapacitive Sodium Storage
Fluorine triggered surface and lattice regulation are simultaneously realized in anatase TiO2 −xFx nanocrystals, which induce improved electron transfer, affluent active exposed crystal facets, and enlarged diffusion channels for efficient faradaic reaction with fast Na+ insertion/extraction. With greatly improved electrode kinetics, the optimized TiO2 −xFx nanocrystals enable ultrastable and ultrafast pseudocapacitive Na+ storage in the electrode. AbstractSodium ‐ion batteries (SIBs) have been considered as one of the most promising secondary battery techniques for large‐scale energy storage applications. ...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Mingzhu Ni, Da Sun, Xiaohui Zhu, Qiuying Xia, Yang Zhao, Liang Xue, Jianghua Wu, Ce Qiu, Qiubo Guo, Zhengyi Shi, Xiaojing Liu, Gongming Wang, Hui Xia Tags: Full Paper Source Type: research

High ‐Resolution Printable and Elastomeric Conductors from Strain‐Adaptive Assemblies of Metallic Nanoparticles with Low Aspect Ratios
In this study, electronic inks comprising silver nanoparticles (AgNPs) for the high ‐resolution printing of stretchable conductors are reported. AgNPs are synthesized using aqueous polyurethane micelles, which are subsequently disentangled into polymeric chains in isopropanol to stabilize the inks. The ink rheology can be arbitrarily tuned to allow direct‐write printing with a minimum feature width of 3 µm. Owing to the absence of extra surfactants, direct drying of such inks at room temperature provides the stretchable conductors with an initial conductivity of 8846 S cm−1 and conductivity of 1305 S cm&min...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Yu Kang, Guoqi Wang, Sanchuan Zhao, Jiaye Li, Lu Di, Yang Feng, Jun Yin, Jian Zhu Tags: Full Paper Source Type: research

Microwave ‐Induced Structural Engineering and Pt Trapping in 6R‐TaS2 for the Hydrogen Evolution Reaction
6R‐TaS2 is newly discovered as electrocatalyst for the hydrogen evolution reaction, investigating its exfoliated 2D forms, microwave ‐induced structural engineering, and Pt trapping effects. AbstractThe nanoengineering of the structure of transition metal dichalcogenides (TMDs) is widely pursued to develop viable catalysts for the hydrogen evolution reaction (HER) alternative to the precious metallic ones. Metallic group ‐5 TMDs have been demonstrated to be effective catalysts for the HER in acidic media, making affordable real proton exchange membrane water electrolysers. Their key‐plus relies on the fact that bot...
Source: Small - November 23, 2020 Category: Nanotechnology Authors: Leyla Najafi, Sebastiano Bellani, Reinier Oropesa ‐Nuñez, Rosaria Brescia, Mirko Prato, Lea Pasquale, Cansunur Demirci, Filippo Drago, Beatriz Martín‐García, Jan Luxa, Liberato Manna, Zdeněk Sofer, Francesco Bonaccorso Tags: Full Paper Source Type: research

Self ‐Assembly of Soft Cellulose Nanospheres into Colloidal Gel Layers with Enhanced Protein Adsorption Capability for Next‐Generation Immunoassays
Cationic cellulose nanospheres form a uniform, interpenetrated colloidal layer on paper surfaces with high molecular accessibility. Such colloidal layer features significantly higher protein adsorption capacity than typical polymer coatings and can be used to overcome the sensitivity limitations of current immunosensors. AbstractSoft cationic core/shell cellulose nanospheres can deform and interpenetrate allowing their self ‐assembly into densely packed colloidal nanogel layers. Taking advantage of their water‐swelling capacity and molecular accessibility, the nanogels are proposed as a new and promising type of coatin...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Katariina Solin, Marco Beaumont, Sabine Rosenfeldt, Hannes Orelma, Maryam Borghei, Markus Bacher, Martina Opietnik, Orlando J. Rojas Tags: Full Paper Source Type: research

Multi ‐Component Mesocrystalline Nanoparticles with Enhanced Photocatalytic Activity
This study suggests a new nanostructure not only exhibiting material‐dependent properties, but also utilizing synergetic properties of unit nanocrystals, simultaneously. AbstractMesocrystals, consisting of small subunits, have gained research interests owing to their ability to simultaneously modify material ‐specific properties and interactions among subunits. However, despite these unique characteristics, most mesocrystals are composed of a single material, and there is a disjunction between academic discovery and practical application. In this study, the synthesis of multi‐component mesocrystalli ne nanoparticles ...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Min Jun Ko, Bum Chul Park, Thomas Myeongseok Koo, Yoo Sang Jeon, Myeong Soo Kim, Young Keun Kim Tags: Full Paper Source Type: research

Complex Morphogenesis by a Model Intrinsically Disordered Protein
In this study, a model silk‐elastin‐like recombinamer capable of interacting via three non‐covalent interactions, namely hydrophobic, ion‐pairing, and H‐bonding is built. This model material is s hown to self‐assemble into complex stable micrometer‐sized biomorphs. Variation of the block composition, pH, and temperature demonstrates the necessary interplay of all three interactions for the formation of such complex structures. (Source: Small)
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Constancio Gonz ález‐Obeso, Miguel González‐Pérez, João F. Mano, Matilde Alonso, José Carlos Rodríguez‐Cabello Tags: Full Paper Source Type: research

Controlling Geometry and Flow Through Bacterial Bridges on Patterned Lubricant ‐Infused Surfaces (pLIS)
Here, patterned lubricant infused surfaces (pLIS) are utilized to fabricate connective structure named “bacterial bridges” between bacterial colonies ofPseudomonas aeruginosa by a simple dewetting method. Geometry and distribution of bridges can be controlled. The bacterial bridges have good connectivity to act as bio ‐microfluidic channels to transfer liquids, nutrients, or antibacterial substances between neighboring bacteria clusters. AbstractSpatial control of bacteria and biofilms on surfaces is necessary to understand the biofilm formation and the social interactions between bacterial communities, which...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Wenxi Lei, Peter Krolla, Thomas Schwartz, Pavel A. Levkin Tags: Full Paper Source Type: research

NIR ‐Light‐Activated Ratiometric Fluorescent Hybrid Micelles for High Spatiotemporally Controlled Biological Imaging and Chemotherapy
Near infrared (NIR) ‐light‐activated ratiometric fluorescent hybrid micelles (RFHM) via the co‐assembly of upconversion nanoparticles (UCNPs), doxorubicin (DOX), and UV‐light‐responsive polymer are generated. NIR light, which can be converted to UV light by UCNPs, can not only remotely regulate the ratiometri c fluorescence imaging of RFHM in tumor tissue, but also trigger DOX release from RFHM to inhibit tumor growth. AbstractIntelligent ‐responsive imaging‐therapy strategy has shown great significance for biomedicine. However, it is still a challenge to construct spatiotemporally controlled imaging‐therap...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Yu Chen, Teng Ma, Pei Liu, Jingli Ren, Yuce Li, Hao Jiang, Lianbin Zhang, Jintao Zhu Tags: Full Paper Source Type: research

2D Material Based Advanced Membranes for Separations in Organic Solvents
2D materials are promising material candidates for next ‐generation membranes due to their unique properties. Several 2D materials, including graphene and nongraphene‐based materials, as membrane materials for organic solvent separation, are reviewed. The critical challenges are discussed to provide a perspective on developing novel 2D material membr anes for advancing organic separation techniques. Abstract2D materials have shown high potentials for fabricating next ‐generation membranes. To date, extensive studies have focused on the applications of 2D material membranes in gas and aqueous media. Recently, compelli...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Xiao Sui, Ziwen Yuan, Yanxi Yu, Kunli Goh, Yuan Chen Tags: Review Source Type: research

Self ‐Assembly of Soft Cellulose Nanospheres into Colloidal Gel Layers with Enhanced Protein Adsorption Capability for Next‐Generation Immunoassays
Cationic cellulose nanospheres form a uniform, interpenetrated colloidal layer on paper surfaces with high molecular accessibility. Such colloidal layer features significantly higher protein adsorption capacity than typical polymer coatings and can be used to overcome the sensitivity limitations of current immunosensors. AbstractSoft cationic core/shell cellulose nanospheres can deform and interpenetrate allowing their self ‐assembly into densely packed colloidal nanogel layers. Taking advantage of their water‐swelling capacity and molecular accessibility, the nanogels are proposed as a new and promising type of coatin...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Katariina Solin, Marco Beaumont, Sabine Rosenfeldt, Hannes Orelma, Maryam Borghei, Markus Bacher, Martina Opietnik, Orlando J. Rojas Tags: Full Paper Source Type: research

Multi ‐Component Mesocrystalline Nanoparticles with Enhanced Photocatalytic Activity
This study suggests a new nanostructure not only exhibiting material‐dependent properties, but also utilizing synergetic properties of unit nanocrystals, simultaneously. AbstractMesocrystals, consisting of small subunits, have gained research interests owing to their ability to simultaneously modify material ‐specific properties and interactions among subunits. However, despite these unique characteristics, most mesocrystals are composed of a single material, and there is a disjunction between academic discovery and practical application. In this study, the synthesis of multi‐component mesocrystalli ne nanoparticles ...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Min Jun Ko, Bum Chul Park, Thomas Myeongseok Koo, Yoo Sang Jeon, Myeong Soo Kim, Young Keun Kim Tags: Full Paper Source Type: research

Complex Morphogenesis by a Model Intrinsically Disordered Protein
In this study, a model silk‐elastin‐like recombinamer capable of interacting via three non‐covalent interactions, namely hydrophobic, ion‐pairing, and H‐bonding is built. This model material is s hown to self‐assemble into complex stable micrometer‐sized biomorphs. Variation of the block composition, pH, and temperature demonstrates the necessary interplay of all three interactions for the formation of such complex structures. (Source: Small)
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Constancio Gonz ález‐Obeso, Miguel González‐Pérez, João F. Mano, Matilde Alonso, José Carlos Rodríguez‐Cabello Tags: Full Paper Source Type: research

Controlling Geometry and Flow Through Bacterial Bridges on Patterned Lubricant ‐Infused Surfaces (pLIS)
Here, patterned lubricant infused surfaces (pLIS) are utilized to fabricate connective structure named “bacterial bridges” between bacterial colonies ofPseudomonas aeruginosa by a simple dewetting method. Geometry and distribution of bridges can be controlled. The bacterial bridges have good connectivity to act as bio ‐microfluidic channels to transfer liquids, nutrients, or antibacterial substances between neighboring bacteria clusters. AbstractSpatial control of bacteria and biofilms on surfaces is necessary to understand the biofilm formation and the social interactions between bacterial communities, which...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Wenxi Lei, Peter Krolla, Thomas Schwartz, Pavel A. Levkin Tags: Full Paper Source Type: research

NIR ‐Light‐Activated Ratiometric Fluorescent Hybrid Micelles for High Spatiotemporally Controlled Biological Imaging and Chemotherapy
Near infrared (NIR) ‐light‐activated ratiometric fluorescent hybrid micelles (RFHM) via the co‐assembly of upconversion nanoparticles (UCNPs), doxorubicin (DOX), and UV‐light‐responsive polymer are generated. NIR light, which can be converted to UV light by UCNPs, can not only remotely regulate the ratiometri c fluorescence imaging of RFHM in tumor tissue, but also trigger DOX release from RFHM to inhibit tumor growth. AbstractIntelligent ‐responsive imaging‐therapy strategy has shown great significance for biomedicine. However, it is still a challenge to construct spatiotemporally controlled imaging‐therap...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Yu Chen, Teng Ma, Pei Liu, Jingli Ren, Yuce Li, Hao Jiang, Lianbin Zhang, Jintao Zhu Tags: Full Paper Source Type: research

2D Material Based Advanced Membranes for Separations in Organic Solvents
2D materials are promising material candidates for next ‐generation membranes due to their unique properties. Several 2D materials, including graphene and nongraphene‐based materials, as membrane materials for organic solvent separation, are reviewed. The critical challenges are discussed to provide a perspective on developing novel 2D material membr anes for advancing organic separation techniques. Abstract2D materials have shown high potentials for fabricating next ‐generation membranes. To date, extensive studies have focused on the applications of 2D material membranes in gas and aqueous media. Recently, compelli...
Source: Small - November 20, 2020 Category: Nanotechnology Authors: Xiao Sui, Ziwen Yuan, Yanxi Yu, Kunli Goh, Yuan Chen Tags: Review Source Type: research

1D/2D Heterostructured Photocatalysts: From Design and Unique Properties to Their Environmental Applications
With the progress of dissimilar dimensional materials, 1D and 2D materials are extensively investigated as heterogeneous photocatalysts, which realize the unique dimensionality ‐dependent advantages and mitigate the disadvantages during environmental and sustainable energy applications. 1D/2D heterojunctions could present rapid carrier transfer along the 1D nanostructures and prevent charge recombination by matching the band potential and interface engineering. AbstractWith the progress of dissimilar dimensional materials, 1D and 2D materials have been extensively investigated as heterogeneous photocatalysts, which reali...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Zuoli He, Jing Zhang, Xuan Li, Shengnan Guan, Mingchong Dai, Shuguang Wang Tags: Review Source Type: research

Hydrogels: The Next Generation Body Materials for Microfluidic Chips?
Can hydrogels become another material choice for the construction of microfluidic chips, particularly biofluidics? Following the loop of “application‐material‐process‐equipment‐device,” the concept of hydrogel‐based microfluidic chips (HMCs) is systematically established concerning three main issues: i) Why choosing hydrogels as the body material for microfluidic chips? ii) How to fabricate HMCs? and iii) In which field s to apply HMCs? AbstractThe integration of microfluidics with biomedical research is confronted with considerable limitations due to its body materials. With high content of water, hy...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Jing Nie, Jianzhong Fu, Yong He Tags: Review Source Type: research

Lithium ‐Ion Batteries: Dual Buffering Inverse Design of Three‐Dimensional Graphene‐Supported Sn‐TiO2 Anodes for Durable Lithium‐Ion Batteries (Small 46/2020)
In article number2004861, Soojin Park, Hyunjung Lee, and co ‐workers present an inverse design for high‐capacity Sn anodes that ensures the structural stability of three‐dimensional freestanding electrodes as incorporated with dual buffers. Outmost TiO2 nanoshells as a mechanically stable passivation layer allow for inward reversible breathing of Sn anodes while macroporous rGO framework provides an open structure for uniform Li ‐ion diffusion and continuous electron pathway to enable fast and durable battery operation. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Jaegeon Ryu, Hyunji Kim, Jieun Kang, Hyunwoo Bark, Soojin Park, Hyunjung Lee Tags: Cover Picture Source Type: research

Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020)
In article number2004345, Bang ‐Ping Jiang, Xing‐Can Shen, and co‐workers develop one type of brand‐new artificial metalloprotein nanoanalogues for enhanced photoimmunotherapy via reasonably integrating “phototherapy‐enzymatic” RuO2 and model antigen ovalbumin. This ushers a prospect of concurrently enhancing photodynamic therapy and reversing the immunosuppressive tumor microenvironment by in situ catalyzing overexpressed H2O2 to produce O2. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Rongtao Huang, Zhaoyang Ding, Bang ‐Ping Jiang, Zilan Luo, Ting Chen, Zhengxi Guo, Shi‐Chen Ji, Hong Liang, Xing‐Can Shen Tags: Back Cover Source Type: research

Tumor Targeting: A Strategy for Tumor Targeting by Higher ‐Order Glycan Pattern Recognition: Synthesis and In Vitro and In Vivo Properties of Glycoalbumins Conjugated with Four Different N‐Glycan Molecules (Small 46/2020)
In article number2004831, Almira Kurbangalieva, Katsunori Tanaka, and co ‐workers successfully apply the glycan pattern recognition mechanisms for developing a promising cancer targeting strategy in both cell‐ and mouse‐based experiments. The use of the very fast, selective and effective RIKEN click reaction allows to synthesize and screen various structurally well ‐defined glycoalbumins containing four different N‐glycan structures in a very short time, as novel diagnostic, prophylactic, and therapeutic agents. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Ivan Smirnov, Regina Sibgatullina, Sayaka Urano, Tsuyoshi Tahara, Peni Ahmadi, Yasuyoshi Watanabe, Ambara R. Pradipta, Almira Kurbangalieva, Katsunori Tanaka Tags: Inside Back Cover Source Type: research

Metamaterials: Liquid Metal ‐Polymer Microlattice Metamaterials with High Fracture Toughness and Damage Recoverability (Small 46/2020)
Liquid metal ‐based metamaterials show great potential in soft robots, flexible electronics and biomedical applications. In article number2004190, Yang Lu and co ‐workers report gallium (Ga)‐filled microlattice metamaterials fabricated by projection micro‐stereolithography (PμSL) 3D printing, which exhibit exceptional toughness and recoverability due to the tunable properties of Ga at relatively low temperatures, offering new insights for design and m anufacturing of mechanical metamaterials. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Wenqiang Zhang, Juzheng Chen, Xiang Li, Yang Lu Tags: Frontispiece Source Type: research

Multiplexed Immunosensors: An Electrodeposited MXene ‐Ti3C2Tx Nanosheets Functionalized by Task‐Specific Ionic Liquid for Simultaneous and Multiplexed Detection of Bladder Cancer Biomarkers (Small 46/2020)
In article number2002517, Jae Yeong Park and co ‐workers successfully demonstrate a green, facile, and cost‐effective one‐pot deposition mechanism of 2D MXene‐Ti3C2Tx onto gold interdigitated microelectrode within few minutes via electroplating (termed ElectroMXenition). This versatile solution ‐based technique enables the deposition of low‐cost, large‐area, and high‐quality MXene onto conductive electrodes, which is applicable to not only biosensing, but also electronics, optoelectronics, catalysis, and renewable energy. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Md. Sharifuzzaman, Sharat Chandra Barman, Md. Abu Zahed, Sudeep Sharma, Hyosang Yoon, Joong San Nah, Hyunsik Kim, Jae Yeong Park Tags: Inside Front Cover Source Type: research

Bottom ‐Up Synthesis of MoS2/CNTs Hollow Polyhedron with 1T/2H Hybrid Phase for Superior Potassium‐Ion Storage
Small, Volume 16, Issue 46, November 19, 2020. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Kuan Wu, Xu Cao, Minyue Li, Bo Lei, Jing Zhan, Minghong Wu Tags: Correction Source Type: research

Masthead: (Small 46/2020)
Small, Volume 16, Issue 46, November 19, 2020. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Tags: Masthead Source Type: research

Dual Buffering Inverse Design of Three ‐Dimensional Graphene‐Supported Sn‐TiO2 Anodes for Durable Lithium‐Ion Batteries
Inverse design for high ‐capacity Sn anodes ensures the structural stability of 3D freestanding electrodes as incorporated with dual buffers. Outmost TiO2 nanoshells as a mechanically stable passivation layer allow for inward reversible breathing of Sn anodes while macroporous rGO framework provides an open structure for uniform lithium ‐ion diffusion and continuous electron pathway to enable fast and durable battery operation. AbstractStable battery operation involving high ‐capacity electrode materials such as tin (Sn) has been plagued by dimensional instability‐driven battery degradation despite the potentially ...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Jaegeon Ryu, Hyunji Kim, Jieun Kang, Hyunwoo Bark, Soojin Park, Hyunjung Lee Tags: Full Paper Source Type: research

Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth
In this study, one type of brand ‐new artificial metalloprotein nanoanalogues is developed via reasonable integration of a “phototherapy‐enzymatic” RuO2 and a model antigen, ovalbumin (OVA) for enhanced PIT of cancers, namely, RuO2‐hybridized OVA nanoanalogues (RuO2@OVA NAs). The RuO2@OVA NAs exhibit remarkable photothermal/photodynamic capabilities under the near ‐infrared light irradiation. More importantly, the photoacoustic imaging and immunofluorescence staining confirm that RuO2@OVA NAs can remarkably alleviate hypoxia via in situ catalysis of hydrogen peroxide overexpressed in the TME to produce ...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Rongtao Huang, Zhaoyang Ding, Bang ‐Ping Jiang, Zilan Luo, Ting Chen, Zhengxi Guo, Shi‐Chen Ji, Hong Liang, Xing‐Can Shen Tags: Full Paper Source Type: research

Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells
Controlled synthesis of high aspect ratio gold nanotubes (AuNTs) is developed to generate AuNTs with tailorable wall thickness microstructure and strong near infrared absorption. Uptake and trafficking studies in primary mesothelial cells demonstrate that these AuNTs escape lysosomal confinement and reside in the perinuclear region, where they have potential to function as cytosolic plasmonic nanoagents. AbstractThe generation of effective and safe nanoagents for biological applications requires their physicochemical characteristics to be tunable, and their cellular interactions to be well characterized. Here, the controll...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Sunjie Ye, Arsalan A. Azad, Joseph E. Chambers, Alison J. Beckett, Lucien Roach, Samuel C. T. Moorcroft, Zabeada Aslam, Ian A. Prior, Alexander F. Markham, P. Louise Coletta, Stefan J. Marciniak, Stephen D. Evans Tags: Full Paper Source Type: research

A Robust and Low ‐Power Bismuth Doped Tin Oxide Memristor Derived from Coaxial Conductive Filaments
A bismuth doped tin oxide memristor with ITO/Bi:SnO2/TiN structure has been fabricated. With the content of 4.8% Bi doping, the self ‐compliance current, switching voltage and operating current of Bi:SnO2 memristor are remarkably smaller than that of ITO/SnO2/TiN device. It is found that the bismuth atoms surround the surface of SnO2 crystals to form the coaxial Bi conductive filament. AbstractMemristor, processing data storage and logic operation all ‐in‐one, is an advanced configuration for next generation computer. In this work, a bismuth doped tin oxide (Bi:SnO2) memristor with ITO/Bi:SnO2/TiN structure has been ...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Yanxin Liu, Cong Ye, Kuan ‐Chang Chang, Lei Li, Bei Jiang, Chen Xia, Lei Liu, Xin Zhang, Xinyi Liu, Tian Xia, Zehui Peng, Guangsen Cao, Gong Cheng, Shanwu Ke, Jiahong Wang Tags: Full Paper Source Type: research

Investigating the Mechanism of Cyclodextrins in the Treatment of Niemann ‐Pick Disease Type C Using Crosslinked 2‐Hydroxypropyl‐β‐cyclodextrin
In conclusion, stable polymerized HPβCDs can elucidate CDs’ mechanism of action while the use of MRIg‐FUS warrants further investigation, as it may be key to harnessing CDs full th erapeutic potential in the NPC treatment. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Dario Carradori, Hsintsung Chen, Beat Werner, Aagam S. Shah, Chiara Leonardi, Mattia Usuelli, Raffaele Mezzenga, Frances Platt, Jean ‐Christophe Leroux Tags: Full Paper Source Type: research

A Strategy for Tumor Targeting by Higher ‐Order Glycan Pattern Recognition: Synthesis and In Vitro and In Vivo Properties of Glycoalbumins Conjugated with Four Different N‐Glycan Molecules
Very fast and selective RIKEN click reaction allows to synthesize and screen various structurally well ‐defined glycoalbumins containing four differentN‐glycan structures in a very short time. Pattern recognition mechanisms for cell targeting in mice represent a novel and promising strategy for diagnostic, prophylactic, and therapeutic agents for various diseases, including cancers. AbstractNatural glycoconjugates that form glycocalyx play important roles in various biological processes based on cell surface recognition through pattern recognition mechanisms. This work represents a new synthesis ‐based screening stra...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Ivan Smirnov, Regina Sibgatullina, Sayaka Urano, Tsuyoshi Tahara, Peni Ahmadi, Yasuyoshi Watanabe, Ambara R. Pradipta, Almira Kurbangalieva, Katsunori Tanaka Tags: Full Paper Source Type: research

Multidimensional Anisotropic Architectures on Polymeric Microparticles
A multidimensional anisotropic framework is established to design next ‐generation suspended miniaturized systems. Here, SU‐8 microparticles are fabricated within a 15D anisotropic space. Their physical attributes are constructed via photolithography. Subsequently, the microparticles are patterned with soft‐lithography forming (bio)molecular and nanoparticle moti fs, consolidating pattern anisotropies while endowing distinct chemical and surface coverage signatures for bespoke multiplexing, Janus, and barcoding applications. AbstractNext generation life science technologies will require the integration of building bl...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Juan Pablo Agusil, Mar ía Isabel Arjona, Marta Duch, Naüm Fusté, José A. Plaza Tags: Full Paper Source Type: research

Liquid Metal ‐Polymer Microlattice Metamaterials with High Fracture Toughness and Damage Recoverability
Gallium ‐based liquid metal‐polymer microlattice metamaterials are fabricated by projection micro‐stereolithography (PμSL) 3D printing and vacuum filling, exhibiting exceptional toughness and recoverability. They can essentially recover original shape upon severe fractures due to the tunable properti es of gallium at a relatively low temperature range, offering new insights into design and manufacturing mechanical metamaterials for soft robots, flexible electronics, and biomedical applications. AbstractBiological materials exhibit excellent fracture toughness due to their ability to dissipate energy during crack p...
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Wenqiang Zhang, Juzheng Chen, Xiang Li, Yang Lu Tags: Communication Source Type: research

Lithium ‐Ion Batteries: Dual Buffering Inverse Design of Three‐Dimensional Graphene‐Supported Sn‐TiO2 Anodes for Durable Lithium‐Ion Batteries (Small 46/2020)
In article number2004861, Soojin Park, Hyunjung Lee, and co ‐workers present an inverse design for high‐capacity Sn anodes that ensures the structural stability of three‐dimensional freestanding electrodes as incorporated with dual buffers. Outmost TiO2 nanoshells as a mechanically stable passivation layer allow for inward reversible breathing of Sn anodes while macroporous rGO framework provides an open structure for uniform Li ‐ion diffusion and continuous electron pathway to enable fast and durable battery operation. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Jaegeon Ryu, Hyunji Kim, Jieun Kang, Hyunwoo Bark, Soojin Park, Hyunjung Lee Tags: Cover Picture Source Type: research

Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020)
In article number2004345, Bang ‐Ping Jiang, Xing‐Can Shen, and co‐workers develop one type of brand‐new artificial metalloprotein nanoanalogues for enhanced photoimmunotherapy via reasonably integrating “phototherapy‐enzymatic” RuO2 and model antigen ovalbumin. This ushers a prospect of concurrently enhancing photodynamic therapy and reversing the immunosuppressive tumor microenvironment by in situ catalyzing overexpressed H2O2 to produce O2. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Rongtao Huang, Zhaoyang Ding, Bang ‐Ping Jiang, Zilan Luo, Ting Chen, Zhengxi Guo, Shi‐Chen Ji, Hong Liang, Xing‐Can Shen Tags: Back Cover Source Type: research

Tumor Targeting: A Strategy for Tumor Targeting by Higher ‐Order Glycan Pattern Recognition: Synthesis and In Vitro and In Vivo Properties of Glycoalbumins Conjugated with Four Different N‐Glycan Molecules (Small 46/2020)
In article number2004831, Almira Kurbangalieva, Katsunori Tanaka, and co ‐workers successfully apply the glycan pattern recognition mechanisms for developing a promising cancer targeting strategy in both cell‐ and mouse‐based experiments. The use of the very fast, selective and effective RIKEN click reaction allows to synthesize and screen various structurally well ‐defined glycoalbumins containing four different N‐glycan structures in a very short time, as novel diagnostic, prophylactic, and therapeutic agents. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Ivan Smirnov, Regina Sibgatullina, Sayaka Urano, Tsuyoshi Tahara, Peni Ahmadi, Yasuyoshi Watanabe, Ambara R. Pradipta, Almira Kurbangalieva, Katsunori Tanaka Tags: Inside Back Cover Source Type: research

Metamaterials: Liquid Metal ‐Polymer Microlattice Metamaterials with High Fracture Toughness and Damage Recoverability (Small 46/2020)
Liquid metal ‐based metamaterials show great potential in soft robots, flexible electronics and biomedical applications. In article number2004190, Yang Lu and co ‐workers report gallium (Ga)‐filled microlattice metamaterials fabricated by projection micro‐stereolithography (PμSL) 3D printing, which exhibit exceptional toughness and recoverability due to the tunable properties of Ga at relatively low temperatures, offering new insights for design and m anufacturing of mechanical metamaterials. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Wenqiang Zhang, Juzheng Chen, Xiang Li, Yang Lu Tags: Frontispiece Source Type: research

Multiplexed Immunosensors: An Electrodeposited MXene ‐Ti3C2Tx Nanosheets Functionalized by Task‐Specific Ionic Liquid for Simultaneous and Multiplexed Detection of Bladder Cancer Biomarkers (Small 46/2020)
In article number2002517, Jae Yeong Park and co ‐workers successfully demonstrate a green, facile, and cost‐effective one‐pot deposition mechanism of 2D MXene‐Ti3C2Tx onto gold interdigitated microelectrode within few minutes via electroplating (termed ElectroMXenition). This versatile solution ‐based technique enables the deposition of low‐cost, large‐area, and high‐quality MXene onto conductive electrodes, which is applicable to not only biosensing, but also electronics, optoelectronics, catalysis, and renewable energy. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Md. Sharifuzzaman, Sharat Chandra Barman, Md. Abu Zahed, Sudeep Sharma, Hyosang Yoon, Joong San Nah, Hyunsik Kim, Jae Yeong Park Tags: Inside Front Cover Source Type: research

Bottom ‐Up Synthesis of MoS2/CNTs Hollow Polyhedron with 1T/2H Hybrid Phase for Superior Potassium‐Ion Storage
Small, Volume 16, Issue 46, November 19, 2020. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Authors: Kuan Wu, Xu Cao, Minyue Li, Bo Lei, Jing Zhan, Minghong Wu Tags: Correction Source Type: research

Masthead: (Small 46/2020)
Small, Volume 16, Issue 46, November 19, 2020. (Source: Small)
Source: Small - November 19, 2020 Category: Nanotechnology Tags: Masthead Source Type: research